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Alison H. Harrill, Ph.D. - Publications

Affiliations: 
2009 Toxicology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Toxicology
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Skelly DA, Czechanski A, Byers C, Aydin S, Spruce C, Olivier C, Choi K, Gatti DM, Raghupathy N, Keele GR, Stanton A, Vincent M, Dion S, Greenstein I, Pankratz M, ... ... Harrill AH, et al. Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency. Cell Stem Cell. PMID 32795400 DOI: 10.1016/J.Stem.2020.07.005  0.365
2020 You D, Lyn-Cook LE, Gatti DM, Bell N, Mayeux PR, James LP, Mattes WB, Larson GJ, Harrill AH. Nitrosative stress and lipid homeostasis as a mechanism for zileuton hepatotoxicity and resistance in genetically sensitive mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32170957 DOI: 10.1093/Toxsci/Kfaa037  0.419
2020 Harrill AH, Sanders AP. Urinary MicroRNAs in Environmental Health: Biomarkers of Emergent Kidney Injury and Disease. Current Environmental Health Reports. PMID 32166731 DOI: 10.1007/S40572-020-00271-8  0.303
2017 Harrill AH, Lin H, Tobacyk J, C Seely J. Mouse population-based evaluation of urinary protein and miRNA biomarker performance associated with cisplatin renal injury. Experimental Biology and Medicine (Maywood, N.J.). 1535370217740854. PMID 29110506 DOI: 10.1177/1535370217740854  0.413
2017 Harrill AH, McAllister KA. New Rodent Population Models May Inform Human Health Risk Assessment and Identification of Genetic Susceptibility to Environmental Exposures. Environmental Health Perspectives. 125: 086002. PMID 28886592 DOI: 10.1289/Ehp1274  0.322
2016 Harrill AH, Moggs JG, Adkins KK, Augustin HG, Johnson RC, Leach MW. A Synopsis of the "Influence of Epigenetics, Genetics, and Immunology" Session Part A at the 35th Annual Society of Toxicologic Pathology Symposium. Toxicologic Pathology. PMID 27708198 DOI: 10.1177/0192623316670781  0.365
2016 Harrill AH, McCullough SD, Wood CE, Kahle JJ, Chorley BN. MicroRNA Biomarkers of Toxicity in Biological Matrices. Toxicological Sciences : An Official Journal of the Society of Toxicology. 152: 264-72. PMID 27462126 DOI: 10.1093/Toxsci/Kfw090  0.316
2015 Church RJ, Otieno M, McDuffie JE, Singh B, Sonee M, Hall L, Watkins PB, Ellinger-Ziegelbauer H, Harrill AH. Beyond miR-122: Identification of microRNA alterations in blood during a time course of hepatobiliary injury and biliary hyperplasia in rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26614776 DOI: 10.1093/Toxsci/Kfv260  0.302
2015 Shi Q, Yang X, Mattes WB, Mendrick DL, Harrill AH, Beger RD. Circulating mitochondrial biomarkers for drug-induced liver injury. Biomarkers in Medicine. PMID 26507261 DOI: 10.2217/Bmm.15.59  0.352
2015 Miousse IR, Currie R, Datta K, Ellinger-Ziegelbauer H, French JE, Harrill AH, Koturbash I, Lawton M, Mann D, Meehan RR, Moggs JG, O'Lone R, Rasoulpour RJ, Pera RA, Thompson K. Importance of investigating epigenetic alterations for industry and regulators: an appraisal of current efforts by the Health and Environmental Sciences Institute. Toxicology. PMID 26134581 DOI: 10.1016/J.Tox.2015.06.009  0.341
2015 Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, ... ... Harrill AH, et al. A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2. Plos Genetics. 11: e1004850. PMID 25679959 DOI: 10.1371/Journal.Pgen.1004850  0.527
2015 Church RJ, Gatti DM, Urban TJ, Long N, Yang X, Shi Q, Eaddy JS, Mosedale M, Ballard S, Churchill GA, Navarro V, Watkins PB, Threadgill DW, Harrill AH. Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 76: 19-26. PMID 25446466 DOI: 10.1016/J.Fct.2014.11.008  0.563
2014 Singhal R, Harrill AH, Menguy-Vacheron F, Jayyosi Z, Benzerdjeb H, Watkins PB. Benign elevations in serum aminotransferases and biomarkers of hepatotoxicity in healthy volunteers treated with cholestyramine. Bmc Pharmacology & Toxicology. 15: 42. PMID 25086653 DOI: 10.1186/2050-6511-15-42  0.366
2014 Mosedale M, Wu H, Kurtz CL, Schmidt SP, Adkins K, Harrill AH. Dysregulation of protein degradation pathways may mediate the liver injury and phospholipidosis associated with a cationic amphiphilic antibiotic drug. Toxicology and Applied Pharmacology. 280: 21-9. PMID 24967691 DOI: 10.1016/J.Taap.2014.06.013  0.465
2014 Church RJ, Wu H, Mosedale M, Sumner SJ, Pathmasiri W, Kurtz CL, Pletcher MT, Eaddy JS, Pandher K, Singer M, Batheja A, Watkins PB, Adkins K, Harrill AH. A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 140: 481-92. PMID 24848797 DOI: 10.1093/Toxsci/Kfu094  0.456
2014 Harrill AH, Eaddy JS, Rose K, Cullen JM, Ramanathan L, Wanaski S, Collins S, Ho Y, Watkins PB, Lecluyse EL. Liver biomarker and in vitro assessment confirm the hepatic origin of aminotransferase elevations lacking histopathological correlate in beagle dogs treated with GABAA receptor antagonist NP260. Toxicology and Applied Pharmacology. 277: 131-7. PMID 24699182 DOI: 10.1016/J.Taap.2014.03.015  0.374
2014 Thulin P, Nordahl G, Gry M, Yimer G, Aklillu E, Makonnen E, Aderaye G, Lindquist L, Mattsson CM, Ekblom B, Antoine DJ, Park BK, Linder S, Harrill AH, Watkins PB, et al. Keratin-18 and microRNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts. Liver International : Official Journal of the International Association For the Study of the Liver. 34: 367-78. PMID 24118944 DOI: 10.1111/Liv.12322  0.386
2014 Church RJ, McDuffie JE, Sonee M, Otieno M, Ma JY, Liu X, Watkins PB, Harrill AH. MicroRNA-34c-3p is an early predictive biomarker for doxorubicin-induced glomerular injury progression in male Sprague-Dawley rats Toxicology Research. 3: 384-394. DOI: 10.1039/C4Tx00051J  0.342
2014 Antoine DJ, Harrill AH, Watkins PB, Park BK. Safety biomarkers for drug-induced liver injury-current status and future perspectives Toxicology Research. 3: 75-85. DOI: 10.1039/C3Tx50077B  0.393
2012 Harrill AH, Desmet KD, Wolf KK, Bridges AS, Eaddy JS, Kurtz CL, Hall JE, Paine MF, Tidwell RR, Watkins PB. A mouse diversity panel approach reveals the potential for clinical kidney injury due to DB289 not predicted by classical rodent models. Toxicological Sciences : An Official Journal of the Society of Toxicology. 130: 416-26. PMID 22940726 DOI: 10.1093/Toxsci/Kfs238  0.405
2012 Howell BA, Yang Y, Kumar R, Woodhead JL, Harrill AH, Clewell HJ, Andersen ME, Siler SQ, Watkins PB. In vitro to in vivo extrapolation and species response comparisons for drug-induced liver injury (DILI) using DILIsymâ„¢: a mechanistic, mathematical model of DILI. Journal of Pharmacokinetics and Pharmacodynamics. 39: 527-41. PMID 22875368 DOI: 10.1007/S10928-012-9266-0  0.369
2012 Harrill AH, Roach J, Fier I, Eaddy JS, Kurtz CL, Antoine DJ, Spencer DM, Kishimoto TK, Pisetsky DS, Park BK, Watkins PB. The effects of heparins on the liver: Application of mechanistic serum biomarkers in a randomized study in healthy volunteers Clinical Pharmacology and Therapeutics. 92: 214-220. PMID 22739141 DOI: 10.1038/Clpt.2012.40  0.352
2009 Gatti DM, Harrill AH, Wright FA, Threadgill DW, Rusyn I. Replication and narrowing of gene expression quantitative trait loci using inbred mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 437-46. PMID 19609828 DOI: 10.1007/S00335-009-9199-0  0.536
2009 Harrill AH, Ross PK, Gatti DM, Threadgill DW, Rusyn I. Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel. Toxicological Sciences : An Official Journal of the Society of Toxicology. 110: 235-43. PMID 19420014 DOI: 10.1093/Toxsci/Kfp096  0.585
2009 Harrill AH, Watkins PB, Su S, Ross PK, Harbourt DE, Stylianou IM, Boorman GA, Russo MW, Sackler RS, Harris SC, Smith PC, Tennant R, Bogue M, Paigen K, Harris C, et al. Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans. Genome Research. 19: 1507-15. PMID 19416960 DOI: 10.1101/Gr.090241.108  0.584
2008 Harrill AH, Rusyn I. Systems biology and functional genomics approaches for the identification of cellular responses to drug toxicity. Expert Opinion On Drug Metabolism & Toxicology. 4: 1379-89. PMID 18950280 DOI: 10.1517/17425255.4.11.1379  0.371
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