John W. Regan - Publications

Affiliations: 
Neuroscience University of Arizona, Tucson, AZ 
Area:
Neuroscience Biology, Pharmacology, Cell Biology

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Year Citation  Score
2022 Kitagawa K, Hamaguchi A, Fukushima K, Nakano Y, Regan JW, Mashimo M, Fujino H. Down-regulation of the expression of cyclooxygenase-2 and prostaglandin E by interleukin-4 is mediated via a reduction in the expression of prostanoid EP4 receptors in HCA-7 human colon cancer cells. European Journal of Pharmacology. 920: 174863. PMID 35240193 DOI: 10.1016/j.ejphar.2022.174863  0.32
2022 Fukushima K, Senoo K, Kurata N, Regan JW, Fujino H. The Gαs-protein-mediated pathway may be steadily stimulated by prostanoid EP2 receptors, but not by EP4 receptors. Febs Open Bio. PMID 35124898 DOI: 10.1002/2211-5463.13378  0.487
2021 Okura I, Hasuoka N, Senoo K, Suganami A, Fukushima K, Regan JW, Mashimo M, Murayama T, Tamura Y, Fujino H. The differential functional coupling of phosphodiesterase 4 to human DP and EP2 prostanoid receptors stimulated with PGD or PGE. Pharmacological Reports : Pr. PMID 33786738 DOI: 10.1007/s43440-021-00247-x  0.481
2020 Endo S, Suganami A, Fukushima K, Senoo K, Araki Y, Regan JW, Mashimo M, Tamura Y, Fujino H. 15-keto-PGEacts as a biased/partial agonist to terminate PGE-evoked signaling. The Journal of Biological Chemistry. PMID 32727851 DOI: 10.1074/Jbc.Ra120.013988  0.552
2020 Kitagawa K, Hamaguchi A, Mashimo M, Regan JW, Fukushima K, Fujino H. Interleukin-4 may suppress expression of E-type prostanoid receptor4 in human colorectal cancer HCA-7 cells. Proceedings For Annual Meeting of the Japanese Pharmacological Society. 93: 2-P-246. DOI: 10.1254/jpssuppl.93.0_2-p-246  0.323
2019 Kurata N, Tokashiki N, Fukushima K, Misao T, Hasuoka N, Kitagawa K, Mashimo M, Regan JW, Murayama T, Fujino H. Short chain fatty acid butyrate uptake reduces expressions of prostanoid EP receptors and their mediation of cyclooxygenase-2 induction in HCA-7 human colon cancer cells. European Journal of Pharmacology. 853: 308-315. PMID 30980797 DOI: 10.1016/J.Ejphar.2019.04.014  0.444
2018 Seira N, Yamagata K, Fukushima K, Araki Y, Kurata N, Yanagisawa N, Mashimo M, Nakamura H, Regan JW, Murayama T, Fujino H. Cellular density-dependent increases in HIF-1α compete with c-Myc to down-regulate human EP4 receptor promoter activity through Sp-1-binding region. Pharmacology Research & Perspectives. 6: e00441. PMID 30455960 DOI: 10.1002/Prp2.441  0.548
2017 Araki Y, Suganami A, Endo S, Masuda Y, Fukushima K, Regan JW, Murayama T, Tamura Y, Fujino H. PGE1 and E3 show lower efficacies than E2 to β-catenin-mediated activity as biased ligands of EP4 prostanoid receptors. Febs Letters. PMID 28986997 DOI: 10.1002/1873-3468.12878  0.429
2016 Suganami A, Fujino H, Okura I, Yanagisawa N, Sugiyama H, Regan JW, Tamura Y, Murayama T. Human DP and EP2 prostanoid receptors take on distinct forms depending on the diverse binding of different ligands. The Febs Journal. PMID 27636113 DOI: 10.1111/Febs.13899  0.576
2015 Fujino H, Seira N, Kurata N, Araki Y, Nakamura H, Regan JW, Murayama T. Prostaglandin E2-stimulated prostanoid EP4 receptors induce prolonged de novo prostaglandin E2 synthesis through biphasic phosphorylation of extracellular signal-regulated kinases mediated by activation of protein kinase A in HCA-7 human colon cancer cells. European Journal of Pharmacology. PMID 26518053 DOI: 10.1016/J.Ejphar.2015.10.044  0.565
2015 Otake S, Yoshida K, Seira N, Sanchez CM, Regan JW, Fujino H, Murayama T. Cellular density-dependent down-regulation of EP4 prostanoid receptors via the up-regulation of hypoxia-inducible factor-1α in HCA-7 human colon cancer cells. Pharmacology Research & Perspectives. 3: e00083. PMID 25692008 DOI: 10.1002/Prp2.83  0.544
2014 Oyama S, Fujino H, Yamazaki R, Okura I, Regan JW, Awata A, Arai T, Murayama T. A novel indole compound, AWT-489, inhibits prostaglandin D2-induced CD55 expression by acting on DP prostanoid receptors as an antagonist in LS174T human colon cancer cells. Archives of Biochemistry and Biophysics. 541: 21-9. PMID 24239863 DOI: 10.1016/J.Abb.2013.10.023  0.459
2013 DiSalvo D, Kuzmich D, Bentzien J, Regan J, Kukulka A, Fadra-Khan T, Nelson R, Harcken C, Thomson D, Nabozny G. Substituted phenyl as a steroid A-ring mimetic: providing agonist activity to a class of arylsulfonamide nonsteroidal glucocorticoid ligands. Bioorganic & Medicinal Chemistry Letters. 23: 6645-9. PMID 24239189 DOI: 10.1016/j.bmcl.2013.10.047  0.314
2013 Yoshida K, Fujino H, Otake S, Seira N, Regan JW, Murayama T. Induction of cyclooxygenase-2 expression by prostaglandin E2 stimulation of the prostanoid EP4 receptor via coupling to Gαi and transactivation of the epidermal growth factor receptor in HCA-7 human colon cancer cells. European Journal of Pharmacology. 718: 408-17. PMID 23973650 DOI: 10.1016/J.Ejphar.2013.08.002  0.531
2012 Ji R, Sanchez CM, Chou CL, Chen XB, Woodward DF, Regan JW. Prostanoid EP₁ receptors mediate up-regulation of the orphan nuclear receptor Nurr1 by cAMP-independent activation of protein kinase A, CREB and NF-κB. British Journal of Pharmacology. 166: 1033-46. PMID 22188298 DOI: 10.1111/J.1476-5381.2011.01817.X  0.678
2011 Fujino H, Toyomura K, Chen XB, Regan JW, Murayama T. Prostaglandin E₂ regulates cellular migration via induction of vascular endothelial growth factor receptor-1 in HCA-7 human colon cancer cells. Biochemical Pharmacology. 81: 379-87. PMID 21070749 DOI: 10.1016/J.Bcp.2010.11.001  0.483
2011 Salinthone S, Schillace RV, Tsang C, Regan JW, Bourdette DN, Carr DW. Lipoic acid stimulates cAMP production via G protein-coupled receptor-dependent and -independent mechanisms. The Journal of Nutritional Biochemistry. 22: 681-90. PMID 21036588 DOI: 10.1016/J.Jnutbio.2010.05.008  0.414
2010 Fujino H, Murayama T, Regan JW. Assessment of constitutive activity in E-type prostanoid receptors. Methods in Enzymology. 484: 95-107. PMID 21036228 DOI: 10.1016/B978-0-12-381298-8.00005-8  0.542
2010 Chandramouli A, Mercado-Pimentel ME, Hutchinson A, Gibadulinová A, Olson ER, Dickinson S, Shañas R, Davenport J, Owens J, Bhattacharyya AK, Regan JW, Pastorekova S, Arumugam T, Logsdon CD, Nelson MA. The induction of S100p expression by the Prostaglandin E₂ (PGE₂)/EP4 receptor signaling pathway in colon cancer cells. Cancer Biology & Therapy. 10: 1056-66. PMID 20890108 DOI: 10.4161/Cbt.10.10.13373  0.543
2010 Hutchinson AJ, Coons SC, Chou CL, Xu W, Stamer WD, Woodward DF, Regan JW. Induction of angiogenic immediate early genes by activation of FP prostanoid receptors in cultured human ciliary smooth muscle cells. Current Eye Research. 35: 408-18. PMID 20450254 DOI: 10.3109/02713680903581021  0.451
2010 Ji R, Chou CL, Xu W, Chen XB, Woodward DF, Regan JW. EP1 prostanoid receptor coupling to G i/o up-regulates the expression of hypoxia-inducible factor-1 alpha through activation of a phosphoinositide-3 kinase signaling pathway. Molecular Pharmacology. 77: 1025-36. PMID 20335389 DOI: 10.1124/Mol.110.063933  0.683
2009 Hutchinson AJ, Chou CL, Israel DD, Xu W, Regan JW. Activation of EP2 prostanoid receptors in human glial cell lines stimulates the secretion of BDNF. Neurochemistry International. 54: 439-46. PMID 19428786 DOI: 10.1016/J.Neuint.2009.01.018  0.742
2009 Israel DD, Regan JW. EP(3) prostanoid receptor isoforms utilize distinct mechanisms to regulate ERK 1/2 activation. Biochimica Et Biophysica Acta. 1791: 238-45. PMID 19416642 DOI: 10.1016/J.Bbalip.2009.01.021  0.75
2009 Xu W, Chou CL, Israel DD, Hutchinson AJ, Regan JW. PGF(2alpha) stimulates FP prostanoid receptor mediated crosstalk between Ras/Raf signaling and Tcf transcriptional activation. Biochemical and Biophysical Research Communications. 381: 625-9. PMID 19248765 DOI: 10.1016/J.Bbrc.2009.02.102  0.767
2008 Taniguchi T, Fujino H, Israel DD, Regan JW, Murayama T. Human EP3(I) prostanoid receptor induces VEGF and VEGF receptor-1 mRNA expression. Biochemical and Biophysical Research Communications. 377: 1173-8. PMID 18996083 DOI: 10.1016/J.Bbrc.2008.10.140  0.753
2008 Xu W, Chou CL, Sun H, Fujino H, Chen QM, Regan JW. FP prostanoid receptor-mediated induction of the expression of early growth response factor-1 by activation of a Ras/Raf/mitogen-activated protein kinase signaling cascade. Molecular Pharmacology. 73: 111-8. PMID 17911534 DOI: 10.1124/Mol.107.038778  0.507
2007 Cherukuri DP, Chen XB, Goulet AC, Young RN, Han Y, Heimark RL, Regan JW, Meuillet E, Nelson MA. The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells. Experimental Cell Research. 313: 2969-79. PMID 17631291 DOI: 10.1016/J.Yexcr.2007.06.004  0.51
2007 Fujino H, Chen XB, Regan JW, Murayama T. Indomethacin decreases EP2 prostanoid receptor expression in colon cancer cells. Biochemical and Biophysical Research Communications. 359: 568-73. PMID 17555711 DOI: 10.1016/J.Bbrc.2007.05.145  0.453
2007 Wada M, DeLong CJ, Hong YH, Rieke CJ, Song I, Sidhu RS, Yuan C, Warnock M, Schmaier AH, Yokoyama C, Smyth EM, Wilson SJ, FitzGerald GA, Garavito RM, Sui de X, ... Regan JW, et al. Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products. The Journal of Biological Chemistry. 282: 22254-66. PMID 17519235 DOI: 10.1074/Jbc.M703169200  0.375
2007 Israel DD, Regan JW. Differential signaling pathway activation and gene regulation among three human prostaglandin E3 (EP3) receptors The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A429  0.733
2006 Regan J, Lee TW, Zindell RM, Bekkali Y, Bentzien J, Gilmore T, Hammach A, Kirrane TM, Kukulka AJ, Kuzmich D, Nelson RM, Proudfoot JR, Ralph M, Pelletier J, Souza D, et al. Quinol-4-ones as steroid A-ring mimetics in nonsteroidal dissociated glucocorticoid agonists. Journal of Medicinal Chemistry. 49: 7887-96. PMID 17181172 DOI: 10.1021/jm061273t  0.305
2006 Chen XB, Regan JW. Activation of the human FP prostanoid receptor disrupts mitosis progression and generates aneuploidy and polyploidy Cellular and Molecular Life Sciences. 63: 112-121. PMID 16378246 DOI: 10.1007/S00018-005-5303-0  0.47
2006 Fujino H, Regan JW. EP(4) prostanoid receptor coupling to a pertussis toxin-sensitive inhibitory G protein. Molecular Pharmacology. 69: 5-10. PMID 16204467 DOI: 10.1124/Mol.105.017749  0.547
2005 Fujino H, Salvi S, Regan JW. Differential regulation of phosphorylation of the cAMP response element-binding protein after activation of EP2 and EP4 prostanoid receptors by prostaglandin E2. Molecular Pharmacology. 68: 251-9. PMID 15855407 DOI: 10.1124/Mol.105.011833  0.551
2004 Fujino H, Vielhauer GA, Regan JW. Prostaglandin E2 selectively antagonizes prostaglandin F2alpha-stimulated T-cell factor/beta-catenin signaling pathway by the FPB prostanoid receptor. The Journal of Biological Chemistry. 279: 43386-91. PMID 15280380 DOI: 10.1074/Jbc.M408276200  0.756
2004 Fujino H, Regan JW. Prostaglandin F2alpha amplifies tumor necrosis factor-alpha promoter activity by the FPB prostanoid receptor. Biochemical and Biophysical Research Communications. 317: 1114-20. PMID 15094384 DOI: 10.1016/J.Bbrc.2004.03.167  0.415
2004 Vielhauer GA, Fujino H, Regan JW. Cloning and localization of hFP(S): a six-transmembrane mRNA splice variant of the human FP prostanoid receptor. Archives of Biochemistry and Biophysics. 421: 175-85. PMID 14984197 DOI: 10.1016/J.Abb.2003.10.021  0.785
2003 Regan JW. EP2 and EP4 prostanoid receptor signaling. Life Sciences. 74: 143-53. PMID 14607241 DOI: 10.1016/J.Lfs.2003.09.031  0.565
2003 Fujino H, Regan JW. Prostanoid receptors and phosphatidylinositol 3-kinase: a pathway to cancer? Trends in Pharmacological Sciences. 24: 335-40. PMID 12871665 DOI: 10.1016/S0165-6147(03)00162-7  0.535
2003 Fujino H, Regan JW. Prostaglandin F(2alpha) stimulation of cyclooxygenase-2 promoter activity by the FP(B) prostanoid receptor. European Journal of Pharmacology. 465: 39-41. PMID 12650831 DOI: 10.1016/S0014-2999(03)01485-7  0.531
2003 Fujino H, Xu W, Regan JW. Prostaglandin E2 induced functional expression of early growth response factor-1 by EP4, but not EP2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases. The Journal of Biological Chemistry. 278: 12151-6. PMID 12566441 DOI: 10.1074/Jbc.M212665200  0.574
2003 Porter AC, Svensson SP, Stamer WD, Bahl JJ, Richman JG, Regan JW. Alpha-2 adrenergic receptors stimulate actin organization in developing fetal rat cardiac myocytes. Life Sciences. 72: 1455-66. PMID 12535714 DOI: 10.1016/S0024-3205(02)02381-0  0.415
2002 Weber TJ, Markillie LM, Chrisler WB, Vielhauer GA, Regan JW. Modulation of JB6 mouse epidermal cell transformation response by the prostaglandin F2alpha receptor. Molecular Carcinogenesis. 35: 163-72. PMID 12489107 DOI: 10.1002/Mc.10079  0.768
2002 Fujino H, Srinivasan D, Regan JW. Cellular conditioning and activation of beta-catenin signaling by the FPB prostanoid receptor. The Journal of Biological Chemistry. 277: 48786-95. PMID 12368277 DOI: 10.1074/Jbc.M209393200  0.628
2002 Srinivasan D, Fujino H, Regan JW. Differential internalization of the prostaglandin f(2alpha) receptor isoforms: role of protein kinase C and clathrin. The Journal of Pharmacology and Experimental Therapeutics. 302: 219-24. PMID 12065720 DOI: 10.1124/Jpet.302.1.219  0.696
2002 Anthony TL, Fujino H, Pierce KL, Yool AJ, Regan JW. Differential regulation of Ca(2+)-dependent Cl- currents by FP prostanoid receptor isoforms in Xenopus oocytes. Biochemical Pharmacology. 63: 1797-806. PMID 12034364 DOI: 10.1016/S0006-2952(02)00953-X  0.507
2002 Huang Y, Stamer WD, Anthony TL, Kumar DV, St John PA, Regan JW. Expression of alpha(2)-adrenergic receptor subtypes in prenatal rat spinal cord. Brain Research. Developmental Brain Research. 133: 93-104. PMID 11882340 DOI: 10.1016/S0165-3806(02)00275-4  0.348
2002 Fujino H, West KA, Regan JW. Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2. The Journal of Biological Chemistry. 277: 2614-9. PMID 11706038 DOI: 10.1074/Jbc.M109440200  0.526
2001 Thompson EJ, Gupta A, Vielhauer GA, Regan JW, Bowden GT. The growth of malignant keratinocytes depends on signaling through the PGE(2) receptor EP1. Neoplasia (New York, N.Y.). 3: 402-10. PMID 11687951 DOI: 10.1038/Sj.Neo.7900182  0.729
2001 Ostrom RS, Gregorian C, Drenan RM, Xiang Y, Regan JW, Insel PA. Receptor number and caveolar co-localization determine receptor coupling efficiency to adenylyl cyclase. The Journal of Biological Chemistry. 276: 42063-9. PMID 11533056 DOI: 10.1074/Jbc.M105348200  0.473
2001 Fujino H, Regan JW. FP Prostanoid Receptor Activation of a T-cell Factor/β-Catenin Signaling Pathway Journal of Biological Chemistry. 276: 12489-12492. PMID 11278257 DOI: 10.1074/Jbc.C100039200  0.516
2000 Woodward DF, Krauss AH, Chen J, Gil DW, Kedzie KM, Protzman CE, Shi L, Chen R, Krauss HA, Bogardus A, Dinh HT, Wheeler LA, Andrews SW, Burk RM, Gac T, ... ... Regan JW, et al. Replacement of the carboxylic acid group of prostaglandin f(2alpha) with a hydroxyl or methoxy substituent provides biologically unique compounds. British Journal of Pharmacology. 130: 1933-43. PMID 10952685 DOI: 10.1038/Sj.Bjp.0703462  0.424
2000 Fujino H, Pierce KL, Srinivasan D, Protzman CE, Krauss AH, Woodward DF, Regan JW. Delayed reversal of shape change in cells expressing FP(B) prostanoid receptors. Possible role of receptor resensitization. The Journal of Biological Chemistry. 275: 29907-14. PMID 10893233 DOI: 10.1074/Jbc.M003467200  0.686
2000 Anthony TL, Pierce KL, Regan JW. Characterization of ep prostanoid receptor subtypes in primary cultures of bovine ciliary epithelial cells by immunofluorescent microscopy and functional studies. Current Eye Research. 20: 394-404. PMID 10855034 DOI: 10.1076/0271-3683(200005)2051-1Ft394  0.524
2000 Fujino H, Srinivasan D, Pierce KL, Regan JW. Differential regulation of prostaglandin F(2alpha) receptor isoforms by protein kinase C. Molecular Pharmacology. 57: 353-8. PMID 10648645  0.647
1999 Pierce KL, Fujino H, Srinivasan D, Regan JW. Activation of FP prostanoid receptor isoforms leads to Rho-mediated changes in cell morphology and in the cell cytoskeleton. The Journal of Biological Chemistry. 274: 35944-9. PMID 10585482 DOI: 10.1074/Jbc.274.50.35944  0.691
1999 Fraeyman N, Vanscheeuwijck P, Wang JM, Huang Y, De Potter WP, Regan JW. Changes in the expression of a2-adrenergic receptor subtypes during maturation of neuronal cells from fetal pig superior cervical ganglia Developmental Brain Research. 116: 127-132. PMID 10521556 DOI: 10.1016/S0165-3806(99)00078-4  0.384
1999 Hoyer PB, Marion SL, Stine I, Rueda BR, Hamernik DL, Regan JW, Wise ME. Ovine prostaglandin F2alpha receptor: steroid influence on steady-state levels of luteal mRNA. Endocrine. 10: 105-11. PMID 10451218 DOI: 10.1385/Endo:10:2:105  0.489
1998 Kedzie KM, Donello JE, Krauss HA, Regan JW, Gil DW. A single amino-acid substitution in the EP2 prostaglandin receptor confers responsiveness to prostacyclin analogs Molecular Pharmacology. 54: 584-590. PMID 9730918 DOI: 10.1124/Mol.54.3.584  0.542
1998 Pierce KL, Regan JW. Prostanoid receptor heterogeneity through alternative mRNA splicing. Life Sciences. 62: 1479-83. PMID 9585122 DOI: 10.1016/S0024-3205(98)00093-9  0.579
1998 Richman JG, Regan JW. α2-adrenergic receptors increase cell migration and decrease F-actin labeling in rat aortic smooth muscle cells American Journal of Physiology - Cell Physiology. 274: C654-C662. PMID 9530096 DOI: 10.1152/Ajpcell.1998.274.3.C654  0.422
1998 Anthony TL, Pierce KL, Stamer WD, Regan JW. Prostaglandin F2 alpha receptors in the human trabecular meshwork. Investigative Ophthalmology & Visual Science. 39: 315-21. PMID 9477988  0.347
1998 Regan JW, Richman JG. α2-Adrenergic receptors stimulate cell migration and decrease cytoskeletal organization in rat aortic smooth muscle cells Faseb Journal. 12: A700.  0.304
1997 LeVan TD, Dow SB, Chase PB, Bloom JW, Regan JW, Cunningham E, Halonen M. Evidence for platelet-activating factor receptor subtypes on human polymorphonuclear leukocyte membranes. Biochemical Pharmacology. 54: 1007-12. PMID 9374421 DOI: 10.1016/S0006-2952(97)00249-9  0.539
1997 Svensson SPS, Porter AC, Regan JW. Cloning and functional expression of guinea pig atrial α2-adrenergic receptor subtypes Annals of the New York Academy of Sciences. 812: 171-173. PMID 9186732 DOI: 10.1111/J.1749-6632.1997.Tb48162.X  0.505
1997 Woodward DF, Regan JW, Lake S, Ocklind A. The molecular biology and ocular distribution of prostanoid receptors Survey of Ophthalmology. 41: S15-S21. PMID 9154272 DOI: 10.1016/S0039-6257(97)80003-3  0.556
1997 Pierce KL, Bailey TJ, Hoyer PB, Gil DW, Woodward DF, Regan JW. Cloning of a carboxyl-terminal isoform of the prostanoid FP receptor. The Journal of Biological Chemistry. 272: 883-7. PMID 8995377 DOI: 10.1074/Jbc.272.2.883  0.457
1996 Chase PB, Yang JM, Thompson FH, Halonen M, Regan JW. Regional mapping of the human platelet-activating factor receptor gene (PTAFR) to 1p35-->p34.3 by fluorescence in situ hybridization. Cytogenetics and Cell Genetics. 72: 205-7. PMID 8978777 DOI: 10.1159/000134190  0.401
1996 Stamer WD, Huang Y, Seftor RE, Svensson SS, Snyder RW, Regan JW. Cultured human trabecular meshwork cells express functional alpha 2A adrenergic receptors. Investigative Ophthalmology & Visual Science. 37: 2426-33. PMID 8933759  0.365
1996 Svensson SPS, Bailey TJ, Porter AC, Richman JG, Regan JW. Heterologous expression of the cloned guinea pig α2A, α2B, and α2C adrenoceptor subtypes: Radioligand binding and functional coupling to a cAMP-responsive reporter gene Biochemical Pharmacology. 51: 291-300. PMID 8573196 DOI: 10.1016/0006-2952(95)02179-5  0.426
1996 Pierce KL, Yool AJ, Moyer PB, Gil DW, Woodward DE, Regan JW. Cloning of a novel isoform of the sheep FP prostaglandin receptor Proceedings of the Western Pharmacology Society. 39: 104.  0.475
1995 Stamer WD, Seftor RE, Snyder RW, Regan JW. Cultured human trabecular meshwork cells express aquaporin-1 water channels. Current Eye Research. 14: 1095-1100. PMID 8974838 DOI: 10.3109/02713689508995815  0.3
1995 Woodward DF, Bogardus AM, Donello JE, Fairbairn CE, Gil DW, Kedzie KM, Burke JA, Kharlamb A, Runde E, Andrews SW, Pierce KL, Regan JW. Molecular characterization and ocular hypotensive properties of the prostanoid EP2 receptor Journal of Ocular Pharmacology and Therapeutics. 11: 447-454. PMID 8590276  0.506
1995 Burkey TH, Regan JW. Activation of Mitogen-Activated Protein Kinase by the Human Prostaglandin EP3A Receptor Biochemical and Biophysical Research Communications. 211: 152-158. PMID 7779081 DOI: 10.1006/Bbrc.1995.1790  0.437
1995 Graves PE, Pierce KL, Bailey TJ, Rueda BR, Gil DW, Woodward DF, Yool AJ, Hoyer PB, Regan JW. Cloning of a receptor for prostaglandin F2 alpha from the ovine corpus luteum. Endocrinology. 136: 3430-6. PMID 7628379 DOI: 10.1210/Endo.136.8.7628379  0.513
1995 Bylund DB, Regan JW, Faber JE, Hieble JP, Triggle CR, Ruffolo RR. Vascular alpha-adrenoceptors: from the gene to the human. Canadian Journal of Physiology and Pharmacology. 73: 533-43. PMID 7585318 DOI: 10.1139/y95-068  0.34
1995 Woodward DF, Pepperl DJ, Burkey TH, Regan JW. 6-isopropoxy-9-oxoxanthene-2-carboxylic acid (AH 6809), a human EP2 receptor antagonist Biochemical Pharmacology. 50: 1731-1733. PMID 7503778 DOI: 10.1016/0006-2952(95)02035-7  0.56
1995 Huang Y, Gil DW, Vanscheeuwijck P, Stamer WD, Regan JW. Localization of alpha 2-adrenergic receptor subtypes in the anterior segment of the human eye with selective antibodies. Investigative Ophthalmology & Visual Science. 36: 2729-39. PMID 7499095  0.344
1995 Pierce KL, Gil DW, Woodward DF, Regan JW. Cloning of human prostanoid receptors. Trends in Pharmacological Sciences. 16: 253-6. PMID 7482980 DOI: 10.1016/S0165-6147(00)89035-5  0.533
1994 Regan JW, Bailey TJ, Pepperl DJ, Pierce KL, Bogardus AM, Donello JE, Fairbairn CE, Kedzie KM, Woodward DF, Gil DW. Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype. Molecular Pharmacology. 46: 213-20. PMID 8078484  0.484
1994 Regan JW, Bailey TJ, Donello JE, Pierce KL, Pepperl DJ, Zhang D, Kedzie KM, Fairbairn CE, Bogardus AM, Woodward DF. Molecular cloning and expression of human EP3 receptors: evidence of three variants with differing carboxyl termini. British Journal of Pharmacology. 112: 377-85. PMID 8075855 DOI: 10.1111/J.1476-5381.1994.Tb13082.X  0.522
1994 Chase PB, Regan JW, Halonen M. Evidence for an intron in the 5'-untranslated region of a human PAF receptor gene Journal of Lipid Mediators and Cell Signalling. 10: 81-82.  0.364
1993 Chase PB, Halonen M, Regan JW. Cloning of a human platelet-activating factor receptor gene: evidence for an intron in the 5'-untranslated region. American Journal of Respiratory Cell and Molecular Biology. 8: 240-4. PMID 8383507 DOI: 10.1165/Ajrcmb/8.3.240  0.416
1993 Vanscheeuwijck P, Huang Y, Schullery D, Regan JW. Antibodies to a Human α2-C10 Adrenergic Receptor Fusion Protein Confirm the Cytoplasmic Orientation of the V-VI Loop Biochemical and Biophysical Research Communications. 190: 340-346. PMID 8381272 DOI: 10.1006/Bbrc.1993.1053  0.456
1993 Pepperl DJ, Regan JW. Selective coupling of α2-adrenergic receptor subtypes to cyclic AMP-dependent reporter gene expression in transiently transfected JEG-3 cells Molecular Pharmacology. 44: 802-809. PMID 8232231  0.382
1993 Svensson SPS, Bailey TJ, Pepperl DJ, Grundstrom N, Ala-Uotila S, Scheinin M, Karlsson JOG, Regan JW. Cloning and expression of a fish α2-adrenoceptor British Journal of Pharmacology. 110: 54-60. PMID 7693288 DOI: 10.1111/J.1476-5381.1993.Tb13771.X  0.574
1992 Perälä M, Hirvonen H, Kalimo H, Ala-Uotila S, Regan JW, Akerman KE, Scheinin M. Differential expression of two alpha 2-adrenergic receptor subtype mRNAs in human tissues. Brain Research. Molecular Brain Research. 16: 57-63. PMID 1334200 DOI: 10.1016/0169-328X(92)90193-F  0.613
1992 Marjamäki A, Ala-Uotila S, Luomala K, Perälä M, Jansson C, Jalkanen M, Regan JW, Scheinin M. Stable expression of recombinant human α2-adrenoceptor subtypes in two mammalian cell lines: characterization with [3H]rauwolscine binding, inhibition of adenylate cyclase and RNase protection assay Bba - Molecular Cell Research. 1134: 169-177. PMID 1313304 DOI: 10.1016/0167-4889(92)90041-9  0.652
1991 Kurose H, Regan JW, Caron MG, Lefkowitz RJ. Functional interactions of recombinant alpha 2 adrenergic receptor subtypes and G proteins in reconstituted phospholipid vesicles. Biochemistry. 30: 3335-41. PMID 1849000 DOI: 10.1021/Bi00227A024  0.749
1991 Maze M, Regan JW. Role of signal transduction in anesthetic action. α2 adrenergic agonists Annals of the New York Academy of Sciences. 625: 409-422. PMID 1711813 DOI: 10.1111/J.1749-6632.1991.Tb33868.X  0.418
1991 Parola AL, Stump DG, Pepperl DJ, Krueger KE, Regan JW, Laird HE. Cloning and expression of a pharmacologically unique bovine peripheral-type benzodiazepine receptor isoquinoline binding protein. The Journal of Biological Chemistry. 266: 14082-7. PMID 1649835  0.307
1991 Onorato JJ, Palczewski K, Regan JW, Caron MG, Lefkowitz RJ, Benovic JL. Role of acidic amino acids in peptide substrates of the β-adrenergic receptor kinase and rhodopsin kinase Biochemistry®. 30: 5118-5125. PMID 1645191 DOI: 10.1021/Bi00235A002  0.681
1990 Lorenz W, Lomasney JW, Collins S, Regan JW, Caron MG, Lefkowitz RJ. Expression of three α2-adrenergic receptor subtypes in rat tissues: Implications for α2 receptor classification Molecular Pharmacology. 38: 599-603. PMID 2172770  0.403
1990 Lomasney JW, Lorenz W, Allen LF, Klng K, Regan JW, Yang-Fengh TL, Caron MG, Lefkowitz RJ. Expansion of the α2-adrenergic receptor family: Cloning and characterization of a human α2-adrenergic receptor subtype, the gene for which is located on chromosome 2 Proceedings of the National Academy of Sciences of the United States of America. 87: 5094-5098. PMID 2164221 DOI: 10.1073/Pnas.87.13.5094  0.797
1990 Michel MC, Regan JW, Gerhardt MA, Neubig RR, Insel PA, Motulsky HJ. Nonadrenergic [3H]idazoxan binding sites are physically distinct from alpha 2-adrenergic receptors. Molecular Pharmacology. 37: 65-8. PMID 2153910  0.386
1990 Cotecchia S, Kobilka BK, Daniel KW, Nolan RD, Lapetina EY, Caron MG, Lefkowitz RJ, Regan JW. Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells. The Journal of Biological Chemistry. 265: 63-9. PMID 2152928  0.677
1990 Seuwen K, Magnaldo I, Kobilka BK, Caron MG, Regan JW, Lefkowitz RJ, Pouysségur J. Alpha 2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human alpha 2-adrenergic receptor gene. Cell Regulation. 1: 445-51. PMID 1981685 DOI: 10.1091/Mbc.1.6.445  0.758
1990 Seuwen K, Magnaldo I, Kobilka BK, Caron MG, Regan JW, Lefkowitz RJ, Pouysségur J. α2-Adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human α2-adrenergic receptor gene Molecular Biology of the Cell. 1: 445-451.  0.552
1989 Hoehe MR, Berrettini WH, Regan JW. A biallelic RFLP of the human α2-C4 adrenergic receptor gene (ADRA2RL2) localized on the short arm of chromosome 4 and encoding the putative α2B receptor is identified with Bsu 36 I, using a 1.5 kb probe (p ADRA2RL2) Nucleic Acids Research. 17: 10148. PMID 2574850 DOI: 10.1093/Nar/17.23.10148  0.488
1989 Fargin A, Raymond JR, Regan JW, Cotecchia S, Lefkowitz RJ, Caron MG. Effector coupling mechanisms of the cloned 5-HT1A receptor Journal of Biological Chemistry. 264: 14848-14852. PMID 2549039  0.417
1989 Matsui H, Lefkowitz RJ, Caron MG, Regan JW. Localization of the fourth membrane spanning domain as a ligand binding site in the human platelet α2-adrenergic receptor Biochemistry. 28: 4125-4130. PMID 2546589 DOI: 10.1021/Bi00435A075  0.774
1989 Catterall WA, Kobilka BK, Kobilka TS, Daniels KW, Regan JW, Caran MG, Lefkowitz RJ. Analysis of ligand binding specificity of receptor chimeras Science. 243: 236-237. PMID 2536189 DOI: 10.1126/SCIENCE.2536189  0.569
1989 Raymond JR, Fargin A, Lohse MJ, Regan JW, Senogles SE, Lefkowitz RJ, Caron MG. Identification of the ligand-binding subunit of the human 5-hydroxytryptamine1A receptor with N-(p-azido-m-[125I] iodophenethyl)spiperone, a high affinity radioiodinated photoaffinity probe. Molecular Pharmacology. 36: 15-21. PMID 2526292  0.57
1989 Kobilka BK, Kobilka TS, Daniels KW, Regan JW, Caran MG, Lefkowitz RJ. Response:Analysis of ligand binding specificity of receptor chimeras Science. 243: 237-237. DOI: 10.1126/Science.243.4888.237  0.671
1989 Matsui H, Lefkowitz RJ, Caron MG, Regan JW. Localization of the fourth membrane spanning domain as a ligand binding site in the human platelet .alpha.2-adrenergic receptor [Erratum to document cited in CA110(21):187980z] Biochemistry. 28: 5702-5702. DOI: 10.1021/Bi00439A054  0.748
1989 Caron MG, Kobilka BK, Bouvier M, Hausdorff WP, Benovic JL, Lohse M, Cotecchia S, Regan JW, Fargin A, Raymond JR, Lefkowitz RJ. Catecholamine Receptors: Structure, Function, and Regulation Recent Progress in Hormone Research. 48: 195-200. DOI: 10.1007/978-3-642-75022-9_21  0.774
1988 Lefkowitz RJ, Kobilka BK, Benovic JL, Bouvier M, Cotecchia S, Hausdorff WP, Dohlman HG, Regan JW, Caron MG. Molecular biology of adrenergic receptors. Cold Spring Harbor Symposia On Quantitative Biology. 53: 507-14. PMID 2855490 DOI: 10.1101/Sqb.1988.053.01.058  0.797
1988 O'Dowd BF, Hnatowich M, Regan JW, Leader WM, Caron MG, Lefkowitz RJ. Site-directed mutagenesis of the cytoplasmic domains of the human β2-adrenergic receptor. Localization of regions involved in G protein-receptor coupling Journal of Biological Chemistry. 263: 15985-15992. PMID 2846532  0.442
1988 Regan JW, Kobilka TS, Yang-Feng TL, Caron MG, Lefkowitz RJ, Kobilka BK. Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype. Proceedings of the National Academy of Sciences of the United States of America. 85: 6301-5. PMID 2842764 DOI: 10.1073/Pnas.85.17.6301  0.776
1988 Kobilka BK, Kobilka TS, Daniel K, Regan JW, Caron MG, Lefkowitz RJ. Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity. Science (New York, N.Y.). 240: 1310-6. PMID 2836950 DOI: 10.1126/Science.2836950  0.766
1987 Benovic JL, Regan JW, Matsui H, Mayor F, Cotecchia S, Leeb-Lundberg LMF, Caron MG, Lefkowitz RJ. Agonist-dependent phosphorylation of the α2-adrenergic receptor by the β-adrenergic receptor kinase Journal of Biological Chemistry. 262: 17251-17253. PMID 2826414  0.709
1987 Kobilka BK, Matsui H, Kobilka TS, Yang-Feng TL, Francke U, Caron MG, Lefkowitz RJ, Regan JW. Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor. Science (New York, N.Y.). 238: 650-6. PMID 2823383 DOI: 10.1126/Science.2823383  0.813
1986 Hiroyasu N, Regan JW, Lefkowitz RJ. Chemical modification of α2-adrenoceptors. Possible role for tyrosine in the ligand binding site Biochemical Pharmacology. 35: 4089-4094. PMID 3022750 DOI: 10.1016/0006-2952(86)90033-X  0.573
1986 Regan JW, Raymond JR, Lefkowitz RJ, DeMarinis RM. Photoaffinity labeling of human platelet and rabbit kidney α2-adrenoceptors with [3H]SKF 102229 Biochemical and Biophysical Research Communications. 137: 606-613. PMID 3015124 DOI: 10.1016/0006-291X(86)91121-6  0.482
1986 Lomasney JW, Leeb-Lundberg LMF, Cotecchia S, Regan JW, DeBernardis JF, Caron MG, Lefkowitz RJ. Mammalian α1-adrenergic receptor. Purification and characterization of the native receptor ligand binding subunit Journal of Biological Chemistry. 261: 7710-7716. PMID 3011796  0.439
1986 Cerione RA, Regan JW, Nakata H, Codina J, Benovic JL, Gierschik P, Somers RL, Spiegel AM, Birnbaumer L, Lefkowitz RJ. Functional reconstitution of the alpha 2-adrenergic receptor with guanine nucleotide regulatory proteins in phospholipid vesicles. The Journal of Biological Chemistry. 261: 3901-9. PMID 3005307  0.394
1986 Regan JW, Nakata H, DeMarinis RM, Caron MG, Lefkowitz RJ. Purification and characterization of the human platelet α2-adrenergic receptor Journal of Biological Chemistry. 261: 3894-3900. PMID 3005306  0.439
1985 Regan JW, DeMarinis RM, Lefkowitz RJ. Arylazide photoaffinity probe for α2-adrenoceptors Biochemical Pharmacology. 34: 3667-3672. PMID 2864929 DOI: 10.1016/0006-2952(85)90228-X  0.515
1984 DeMarinis RM, Krog AJ, Shah DH, Lafferty J, Holden KG, Hieble JP, Matthews WD, Regan JW, Lefkowitz RJ, Caron MG. Development of an affinity ligand for purification of α2-adrenoceptors from human platelet membranes Journal of Medicinal Chemistry. 27: 918-921. PMID 6330361 DOI: 10.1002/Chin.198448242  0.646
1984 Regan JW, DeMarinis RM, Caron MG, Lefkowitz RJ. Identification of the subunit-binding site of α2-adrenergic receptors using [3H]phenoxybenzamine Journal of Biological Chemistry. 259: 7864-7869. PMID 6330087  0.437
1984 DeMarinis R, Krog A, Shah D, Lafferty J, Holden K, Hieble J, Matthews W, Regan J, Lefkowitz R, Caron M. Additions and Corrections-Development of an Affinity Ligand for Purification of Adrenoceptors from Human Platelet Membranes Journal of Medicinal Chemistry. 27: 1753-1753. DOI: 10.1021/Jm00378A603  0.582
1982 Regan JW, Barden N, Lefkowitz RJ, Caron MG, DeMarinis RM, Krog AJ, Holden KG, Matthews WD, Hieble JP. Affinity chromatography of human platelet α 2-adrenergic receptors Proceedings of the National Academy of Sciences of the United States of America. 79: 7223-7227. PMID 6130523 DOI: 10.1073/Pnas.79.23.7223  0.69
1980 Regan JW, Roeske WR, Yamamura HI. 3H-flunitrazepam binding to bovine retina and the effect of GABA thereon Neuropharmacology. 19: 413-414. PMID 6104311 DOI: 10.1016/0028-3908(80)90195-1  0.369
Low-probability matches (unlikely to be authored by this person)
1980 Regan JW, Roeske WR, Yamamura HI. The effect of GABA on the binding of 3H-flunitrazepam in mouse brains during development Brain Research Bulletin. 5: 857-860. DOI: 10.1016/0361-9230(80)90144-6  0.299
2020 Endo S, Senoo K, Takano H, Araki Y, Regan JW, Fukushima K, Fujino H. 15-keto-prostaglandin E2, the metabolite of prostaglandin E2, may work as biased agonist for EP2 and EP4 receptors. Proceedings For Annual Meeting of the Japanese Pharmacological Society. 93: 3-P-353. DOI: 10.1254/jpssuppl.93.0_3-p-353  0.299
1992 Sun L, Schulte N, Pettinger P, Regan JW, Pettinger WA. The frequency of ??2-adrenoceptor restriction fragment length polymorphisms in normotensive and hypertensive humans Journal of Hypertension. 10: 1011???1016. DOI: 10.1097/00004872-199209000-00015  0.297
2000 Anthony TL, Brooks HL, Boassa D, Leonov S, Yanochko GM, Regan JW, Yool AJ. Cloned human aquaporin-1 is a cyclic GMP-gated ion channel. Molecular Pharmacology. 57: 576-88. PMID 10692499 DOI: 10.1124/Mol.57.3.576  0.293
2017 Seira N, Yanagisawa N, Suganami A, Honda T, Wasai M, Regan JW, Fukushima K, Yamaguchi N, Tamura Y, Arai T, Murayama T, Fujino H. Anti-cancer Effects of MW-03, a Novel Indole Compound, by Inducing 15-Hydroxyprostaglandin Dehydrogenase and Cellular Growth Inhibition in the LS174T Human Colon Cancer Cell Line. Biological & Pharmaceutical Bulletin. 40: 1806-1812. PMID 28966256 DOI: 10.1248/Bpb.B17-00458  0.292
2008 Regan J. Editorial: The medicinal chemistry of agents targeting the nuclear hormone receptor Current Topics in Medicinal Chemistry. 8: 727. PMID 18537691 DOI: 10.2174/156802608784535057  0.288
1995 Rueda BR, Botros IW, Pierce KL, Regan JW, Hoyer PB. Comparison of mRNA levels for the PGF(2α) receptor (FP) during luteolysis and early pregnancy in the ovine corpus luteum. Endocrine. 3: 781-7. PMID 21153121 DOI: 10.1007/Bf02935681  0.286
1994 Benezra M, Ben-Sasson SA, Regan J, Chang M, Bar-Shavit R, Vlodavsky I. Antiproliferative activity to vascular smooth muscle cells and receptor binding of heparin-mimicking polyaromatic anionic compounds. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 14: 1992-9. PMID 7981190 DOI: 10.1161/01.ATV.14.12.1992  0.284
1996 Stamer WD, Snyder RW, Burkey TH, Regan JW. Activation of α2A-adrenergic receptors in human trabecular meshwork cells stimulates MAP kinase activity Investigative Ophthalmology and Visual Science. 37: S206.  0.282
1996 Yool AJ, Stamer WD, Regan JW. Forskolin stimulation of water and cation permeability in aquaporin 1 water channels. Science (New York, N.Y.). 273: 1216-8. PMID 8703053 DOI: 10.1126/Science.273.5279.1216  0.27
1988 Daly RN, Sulpizio AC, Levitt B, DeMarinis RM, Regan JW, Ruffolo RR, Hieble JP. Evidence for heterogeneity between pre- and postjunctional alpha-2 adrenoceptors using 9-substituted 3-benzazepines Journal of Pharmacology and Experimental Therapeutics. 247: 122-128. PMID 2902209  0.261
1992 Sun L, McArdle S, Chun M, Wolff DW, Schulte N, Regan JW, Pettinger WA. Mapping of a Dde I RELP of the .ALPHA.2-Adrenoceptor Gene and the Correlation of Genotype with Blood Pressure in the F2 Rats of SHR-WKY Cross. Hypertension Research. 15: 143-148. DOI: 10.1291/Hypres.15.143  0.26
1981 Regan JW, Yamamura HI, Yamada S, Roeske WR. High affinity renal [3H]flunitrazepam binding: Characterization, localization, and alteration in hypertension Life Sciences. 28: 991-998. PMID 6111733 DOI: 10.1016/0024-3205(81)90744-X  0.26
1976 Regan JW, Bjeldanes LF. Metabolism of (+)-limonene in rats Journal of Agricultural and Food Chemistry. 24: 377-380. PMID 815305 DOI: 10.1021/Jf60204A031  0.238
1980 Regan JW, Roeske WR, Yamamura HI. The benzodiazepine receptor: Its development and its modulation by γ-aminobutyric acid Journal of Pharmacology and Experimental Therapeutics. 212: 137-143. PMID 7351621  0.237
1980 Regan JW, Yamamura HI, Yamada S, Roeske WR. Renal benzodiazepine binding increases during deoxycorticosterone/salt hypertension in rats European Journal of Pharmacology. 67: 167-168. PMID 7418732 DOI: 10.1016/0014-2999(80)90029-1  0.223
1992 R. Martin A, Yang Y, L. Nelson D, Regan J. Synthesis of Some 5-Substituted Indoles Heterocycles. 34: 1169. DOI: 10.3987/Com-92-6009  0.218
1980 Regan JW, Morris MM, Nao B, Bjeldanes LF. Metabolism of limonene-1,2-epoxide in the rat Xenobiotica. 10: 859-861. PMID 7210698 DOI: 10.3109/00498258009033819  0.216
1974 Mainoya JR, Bern HA, Regan JW. Influence of ovine prolactin on transport of fluid and sodium chloride by the mammalian intestine and gall bladder Journal of Endocrinology. 63: 311-317. PMID 4443693 DOI: 10.1677/Joe.0.0630311  0.198
1981 Regan JW, Roeske WR, Malick JB, Yamamura SH, Yamamura HI. γ-Aminobutyric acid enhancement of CL 218,872 affinity and evidence of benzodiazepine receptor heterogeneity Molecular Pharmacology. 20: 477-483. PMID 6276709  0.187
1993 Agarwal A, Pearson PP, Taylor EW, Li HB, Dahlgren T, Herslöf M, Yang Y, Lambert G, Nelson DL, Regan JW. Three-dimensional quantitative structure-activity relationships of 5-HT receptor binding data for tetrahydropyridinylindole derivatives: a comparison of the Hansch and CoMFA methods. Journal of Medicinal Chemistry. 36: 4006-14. PMID 8258822 DOI: 10.1021/Jm00077A003  0.181
1991 Kedzie KM, Balfour CA, Escobar GY, Grimm SW, He YA, Pepperl DJ, Regan JW, Stevens JC, Halpert JR. Molecular basis for a functionally unique cytochrome P450IIB1 variant. The Journal of Biological Chemistry. 266: 22515-21. PMID 1718996  0.175
2002 Pargellis C, Tong L, Churchill L, Cirillo PF, Gilmore T, Graham AG, Grob PM, Hickey ER, Moss N, Pav S, Regan J. Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site. Nature Structural Biology. 9: 268-72. PMID 11896401 DOI: 10.1038/Nsb770  0.174
2003 Regan J, Capolino A, Cirillo PF, Gilmore T, Graham AG, Hickey E, Kroe RR, Madwed J, Moriak M, Nelson R, Pargellis CA, Swinamer A, Torcellini C, Tsang M, Moss N. Structure-activity relationships of the p38alpha MAP kinase inhibitor 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796). Journal of Medicinal Chemistry. 46: 4676-86. PMID 14561087 DOI: 10.1021/Jm030121K  0.143
2002 Regan J, Breitfelder S, Cirillo P, Gilmore T, Graham AG, Hickey E, Klaus B, Madwed J, Moriak M, Moss N, Pargellis C, Pav S, Proto A, Swinamer A, Tong L, et al. Pyrazole urea-based inhibitors of p38 MAP kinase: from lead compound to clinical candidate. Journal of Medicinal Chemistry. 45: 2994-3008. PMID 12086485 DOI: 10.1021/Jm020057R  0.139
2003 Cirillo PF, Pargellis C, Regan J. The non-diaryl heterocycle classes of p38 MAP kinase inhibitors. Current Topics in Medicinal Chemistry. 2: 1021-35. PMID 12171569 DOI: 10.2174/1568026023393390  0.136
2011 Betageri R, Gilmore T, Kuzmich D, Kirrane TM, Bentzien J, Wiedenmayer D, Bekkali Y, Regan J, Berry A, Latli B, Kukulka AJ, Fadra TN, Nelson RM, Goldrick S, Zuvela-Jelaska L, et al. Non-steroidal dissociated glucocorticoid agonists: indoles as A-ring mimetics and function-regulating pharmacophores. Bioorganic & Medicinal Chemistry Letters. 21: 6842-51. PMID 21963986 DOI: 10.1016/j.bmcl.2011.09.018  0.135
1996 Stamer WD, Snyder RW, Regan JW. Characterization of the transmembrane orientation of aquaporin-1 using antibodies to recombinant fusion proteins. Biochemistry. 35: 16313-8. PMID 8973206 DOI: 10.1021/bi9619536  0.131
1992 Sun L, Schulte N, Pettinger P, Regan JW, Pettinger WA. The frequency of α2-adrenoceptor restriction fragment length polymorphisms in normotensive and hypertensive humans Journal of Hypertension. 10: 1011-1015. PMID 1357028  0.129
2003 Kroe RR, Regan J, Proto A, Peet GW, Roy T, Landro LD, Fuschetto NG, Pargellis CA, Ingraham RH. Thermal denaturation: a method to rank slow binding, high-affinity P38alpha MAP kinase inhibitors. Journal of Medicinal Chemistry. 46: 4669-75. PMID 14561086 DOI: 10.1021/Jm030120S  0.129
2004 Regan J, Pargellis CA, Cirillo PF, Gilmore T, Hickey ER, Peet GW, Proto A, Swinamer A, Moss N. The kinetics of binding to p38MAP kinase by analogues of BIRB 796. Bioorganic & Medicinal Chemistry Letters. 13: 3101-4. PMID 12941343 DOI: 10.1016/s0960-894x(03)00656-5  0.124
1981 Regan JW, Roeske WR, Ruth WH, Deshmukh P, Yamamura HI. Reductions in retinal γ-aminobutyric acid (GABA) content and in [ 3H]flunitrazepam binding after postnatal monosodium glutamate injections in rats Journal of Pharmacology and Experimental Therapeutics. 218: 791-796. PMID 6267248  0.122
2022 Fan J, Gilmartin K, Octaviano S, Villar F, Remache B, Regan J. Using Human Serum Albumin Binding Affinities as a Proactive Strategy to Affect the Pharmacodynamics and Pharmacokinetics of Preclinical Drug Candidates. Acs Pharmacology & Translational Science. 5: 803-810. PMID 36110380 DOI: 10.1021/acsptsci.2c00115  0.111
2007 Moss N, Breitfelder S, Betageri R, Cirillo PF, Fadra T, Hickey ER, Kirrane T, Kroe RR, Madwed J, Nelson RM, Pargellis CA, Qian KC, Regan J, Swinamer A, Torcellini C. New modifications to the area of pyrazole-naphthyl urea based p38 MAP kinase inhibitors that bind to the adenine/ATP site. Bioorganic & Medicinal Chemistry Letters. 17: 4242-7. PMID 17560108 DOI: 10.1016/J.Bmcl.2007.05.042  0.097
2003 Pargellis C, Regan J. Inhibitors of p38 mitogen-activated protein kinase for the treatment of rheumatoid arthritis. Current Opinion in Investigational Drugs (London, England : 2000). 4: 566-71. PMID 12833650  0.094
2015 Kirchner RM, Corfield PW, Annabi M, Regan J, Speina K, DiProperzio A, Ciaccio JA, Capitani JF. Crystal structure of 2α-(1,1-di-phenyl-eth-yl)-4-methyl-4α,5α-diphenyl-1,3-dioxolane: the result of a non-acid pinacol rearrangement. Acta Crystallographica. Section E, Crystallographic Communications. 71: 1278-82. PMID 26594491 DOI: 10.1107/S2056989015017752  0.079
1982 DANISHEFSKY S, REGAN J. ChemInform Abstract: A MERCURY MEDIATED ROUTE TO THE MITOSENES Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198208201  0.079
1982 DANISHEFSKY S, REGAN J, DOEHNER R. ChemInform Abstract: APPROACHES TO THE SYNTHESIS OF THE MITOMYCINS. A ROUTE TO THE MITOSANES INVOLVING ACTIVATED CYCLOPROPANES Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198218335  0.078
2000 Brooks HL, Regan JW, Yool AJ. Inhibition of aquaporin-1 water permeability by tetraethylammonium: Involvement of the loop E pore region Molecular Pharmacology. 57: 1021-1026. PMID 10779387  0.078
1994 Stamer WD, Snyder RW, Smith BL, Agre P, Regan JW. Localization of aquaporin CHIP in the human eye: implications in the pathogenesis of glaucoma and other disorders of ocular fluid balance. Investigative Ophthalmology & Visual Science. 35: 3867-72. PMID 7523327  0.076
1981 Regan JW, Roeske WR, Ruth W. Reductions in benzodiazepine binding following postnatal monosodium glutamate injections in rats Federation Proceedings. 40: 434.  0.069
2019 Regan J, Karlin-Neumann G. Phasing DNA Markers Using Digital PCR. Methods in Molecular Biology (Clifton, N.J.). 1768: 489-512. PMID 29717461 DOI: 10.1007/978-1-4939-7778-9_28  0.063
1989 Regan JW, Doze VA, Daniel K, Maze M. IS DEXMEDETOMIDINEʼS ANESTHETIC ACTION DEPENDENT ON ISORECEPTOR SELECTIVITY? Anesthesiology. 71: A579. DOI: 10.1097/00000542-198909001-00579  0.061
1993 Huang Y, Vanscheeuwijck P, Regan JW. Precipitation with KCl improves the chemical cross-linking of GST-fusion proteins to agarose after solubilization with SDS Biotechniques. 15: 987+989+992. PMID 8292352  0.057
2014 Hwang VJ, Maar D, Regan J, Angkustsiri K, Simon TJ, Tassone F. Mapping the deletion endpoints in individuals with 22q11.2 deletion syndrome by droplet digital PCR. Bmc Medical Genetics. 15: 106. PMID 25312060 DOI: 10.1186/S12881-014-0106-5  0.052
2016 Smith BD, Bryan GL, Glover SCO, Goldbaum NJ, Turk MJ, Regan J, Wise JH, Schive H, Abel T, Emerick A, O'Shea BW, Anninos P, Hummels CB, Khochfar S. grackle: a chemistry and cooling library for astrophysics Monthly Notices of the Royal Astronomical Society. 466: 2217-2234. DOI: 10.1093/Mnras/Stw3291  0.049
2019 De Bolla P, Jones E, Nulty P, Recchia G, Regan J. The Conceptual Foundations of the Modern Idea of Government in the British Eighteenth Century: A Distributional Concept Analysis International Journal For History, Culture and Modernity. 7. DOI: 10.18352/Hcm.575  0.047
2019 Regan J, Dushaj N, Stinchfield G. Reducing Hexavalent Chromium to Trivalent Chromium with Zero Chemical Footprint: Borohydride Exchange Resin and a Polymer-Supported Base. Acs Omega. 4: 11554-11557. PMID 31460261 DOI: 10.1021/acsomega.9b01194  0.033
1976 Regan JW, Dekar P. Dissonance from counterattitudinal advocacy to liked and disliked targets Journal of Social Psychology. 99: 63-73. DOI: 10.1080/00224545.1976.9924749  0.031
2010 Regan J, Létant S, Adams K, Nguyen N, Derlet R, Cohen S, Vitalis E, Tammero L, Ortiz J, McBride M, Birch J. A sample-in-answer-out instrument for the detection of multiple respiratory pathogens in unprepared nasopharyngeal swab samples. The Analyst. 135: 2316-22. PMID 20596587 DOI: 10.1039/C0An00223B  0.029
2020 Ferrando SJ, Klepacz L, Lynch S, Shahar S, Dornbush R, Smiley A, Miller I, Tavakkoli M, Regan J, Bartell A. Psychiatric emergencies during the height of the COVID-19 pandemic in the suburban New York City area. Journal of Psychiatric Research. PMID 33158555 DOI: 10.1016/j.jpsychires.2020.10.029  0.028
1964 Seneca H, Peer PM, Regan JW. Chemotherapy of experimental Trypanosoma cruzi infection in mice with l -furaltadone Experimental Parasitology. 15: 479-484. PMID 14242260  0.026
1980 Pearsall DW, Regan JW. DESIGNING, MANUFACTURING AND INSTALLING COAL FIRED STEAM GENERATORS FOR RELIABILITY, AVAILABILITY AND MAINTAINABILITY Report - Stanford University, John a. Blume Earthquake Engineering Center. 5-14.  0.024
1985 Manaker AM, Regan JW, Makuch JA, Dunn GC, Aulisio CJ. DESIGN OF THE 160-MW AFBC DEMONSTRATION UNIT AT TVA'S SHAWNEE STEAM PLANT Proceedings of the International Conference On Fluidized Bed Combustion. 1: 370-383.  0.023
2019 Regan J, Dolores J, Lepore M, Gualano M, Badson J, Zimnoch A, Capitani JF, Fan J. Modified silica gels as recyclable adsorbents of aqueous polycyclic aromatic hydrocarbons Green Chemistry Letters and Reviews. 12: 435-443. DOI: 10.1080/17518253.2019.1687760  0.023
2019 DE BOLLA P, JONES E, NULTY P, RECCHIA G, REGAN J. Distributional Concept Analysis Contributions to the History of Concepts. 14: 66-92. DOI: 10.3167/Choc.2019.140104  0.021
2019 Kerber S, Regan JW, Horn GP, Fent KW, Smith DL. Effect of Firefighting Intervention on Occupant Tenability during a Residential Fire Fire Technology. 55: 2289-2316. DOI: 10.1007/S10694-019-00864-2  0.02
2023 Farina FR, Regan J, Marquez M, An H, O'Loughlin P, Pavithra P, Taddeo M, Knight RC, Bennett M, Lenaert B, Griffith JW. Reducing fear and avoidance of memory loss improves mood and social engagement in community-based older adults: a randomized trial. Bmc Geriatrics. 23: 786. PMID 38030988 DOI: 10.1186/s12877-023-04470-4  0.02
2023 Farina FR, Pavithra P, An H, Marquez M, O'Loughlin P, Regan J, Taddeo M, Bennett M, Lenaert B, Griffith JW. Validation of the Fear and Avoidance of Memory Loss scale in community-based older adults. Alzheimer's & Dementia (Amsterdam, Netherlands). 15: e12432. PMID 37101711 DOI: 10.1002/dad2.12432  0.017
2020 Bolla P, Jones E, Nulty P, Recchia G, Regan J. The Idea of Liberty, 1600-1800: A Distributional Concept Analysis. Journal of the History of Ideas. 81: 381-406. PMID 33416754 DOI: 10.1353/Jhi.2020.0023  0.017
1969 Ormonde NWH, Gray JA, Murdoch J, Wallace E, Brumfitt W, Pursell R, Regan JW. Chronic bacteriuria due to escherichia coli. i. assessment of the value of combined short- and long-term treatment with cycloserine, nitrofurantoin, and sulphadimidine Journal of Infectious Diseases. 120: 82-86. PMID 4896009 DOI: 10.1093/infdis/120.1.82  0.016
1975 Regan JW, Gosselink H, Hubsch J, Ulsh E. Do people have inflated views of their own ability? Journal of Personality and Social Psychology. 31: 295-301. PMID 1123715 DOI: 10.1037/h0076300  0.016
2024 Sevilla JP, Tortorice D, Kantor D, Regan J, Meszaros KH, Beck EC, Begum N, Bloom DE. Lifecycle model-based evaluation of infant 4CMenB vaccination in the UK. The European Journal of Health Economics : Hepac : Health Economics in Prevention and Care. PMID 38182698 DOI: 10.1007/s10198-023-01654-y  0.014
1976 Regan JW. Liking for evaluators: Consistency and self-esteem theories Journal of Experimental Social Psychology. 12: 159-169. DOI: 10.1016/0022-1031(76)90067-6  0.013
2020 Healey R, Jones E, Nulty P, Recchia G, Regan J, Bolla Pd. The Uses of Genre Representations. 149: 73-102. DOI: 10.1525/Rep.2020.149.1.73  0.012
2019 Kerber S, Regan JW, Horn GP, Fent KW, Smith DL. Correction to: Effect of Firefighting Intervention on Occupant Tenability during a Residential Fire Fire Technology. 55: 2317-2317. DOI: 10.1007/S10694-019-00875-Z  0.011
2021 O'Loughlin P, Pavithra P, Regan J, Bennett M, Knight R, Lenaert B, Marquez M, Taddeo M, Griffith J, Shapiro R, Farina F. A Randomized Controlled Trial Investigating the Feasibility of a Low-Intensity Psychological Intervention for Fear of Memory Loss and Quality of Life in Older Adults: Protocol for the Reducing Fear and Avoidance of Memory Loss (REFRAME) Study. Jmir Research Protocols. 10: e30514. PMID 34328428 DOI: 10.2196/30514  0.01
2019 Brummel-Smith C, Bryan G, Butsky I, Corlies L, Emerick A, Forbes J, Fujimoto Y, Goldbaum N, Grete P, Hummels C, Kim J, Koh D, Li M, Li Y, Li X, ... ... Regan J, et al. ENZO: An Adaptive Mesh Refinement Code for Astrophysics (Version 2.6) Journal of Open Source Software. 4: 1636. DOI: 10.21105/joss.01636  0.01
2019 Regan JW. Need to necessity: carriage advertising in the Gilded Age History of Retailing and Consumption. 5: 111-132. DOI: 10.1080/2373518X.2019.1611163  0.01
2017 Abell SK, Suen M, Pease A, Boyle JA, Soldatos G, Regan J, Wallace EM, Teede HJ. Pregnancy Outcomes and Insulin Requirements in Women with Type 1 Diabetes Treated with Continuous Subcutaneous Insulin Infusion and Multiple Daily Injections: Cohort Study. Diabetes Technology & Therapeutics. 19: 280-287. PMID 28282241 DOI: 10.1089/dia.2016.0412  0.01
2016 Abell SK, Boyle JA, de Courten B, Knight M, Ranasinha S, Regan J, Soldatos G, Wallace EM, Zoungas S, Teede HJ. Contemporary type 1 diabetes pregnancy outcomes: impact of obesity and glycaemic control. The Medical Journal of Australia. 205: 162-7. PMID 27510344 DOI: 10.5694/mja16.00443  0.01
2009 Kurtz SM, MacDonald D, Ianuzzi A, van Ooij A, Isaza J, Ross ER, Regan J. The natural history of polyethylene oxidation in total disc replacement. Spine. 34: 2369-77. PMID 19789469 DOI: 10.1097/BRS.0b013e3181b20230  0.01
2008 Regan J. Profitable Contradiction Women: a Cultural Review. 19: 116-119. DOI: 10.1080/09574040801920169  0.01
1971 Regan JW. Guilt, perceived injustice, and altruistic behavior Journal of Personality and Social Psychology. 18: 124-132. PMID 5550433 DOI: 10.1037/h0030712  0.01
1969 Cousins PJ, Regan JW. Clinical evaluation of Babisan in 200 infants Nursing Times. 65: 501-502. PMID 4887720  0.01
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