Year |
Citation |
Score |
2022 |
Jacobsen MT, Spaltenstein P, Giesler RJ, Chou DH, Kay MS. Improved Handling of Peptide Segments Using Side Chain-Based "Helping Hand" Solubilizing Tools. Methods in Molecular Biology (Clifton, N.J.). 2530: 81-107. PMID 35761044 DOI: 10.1007/978-1-0716-2489-0_7 |
0.386 |
|
2021 |
Giesler RJ, Spaltenstein P, Jacobsen MT, Xu W, Maqueda M, Kay MS. A glutamic acid-based traceless linker to address challenging chemical protein syntheses. Organic & Biomolecular Chemistry. 19: 8821-8829. PMID 34585207 DOI: 10.1039/d1ob01611c |
0.428 |
|
2020 |
Nishimura Y, Francis JN, Donau OK, Jesteadt E, Sadjadpour R, Smith AR, Seaman MS, Welch BD, Martin MA, Kay MS. Prevention and treatment of SHIVAD8 infection in rhesus macaques by a potent d-peptide HIV entry inhibitor. Proceedings of the National Academy of Sciences of the United States of America. PMID 32820072 DOI: 10.1073/Pnas.2009700117 |
0.599 |
|
2020 |
Ladinsky MS, Gnanapragasam PNP, Yang Z, West AP, Kay MS, Bjorkman PJ. Electron tomography visualization of HIV-1 fusion with target cells using inhibitors to trap the prehairpin intermediate. Elife. 9. PMID 32697193 DOI: 10.7554/Elife.58411 |
0.482 |
|
2020 |
Ladinsky MS, Gnanapragasam PN, Yang Z, West AP, Kay MS, Bjorkman PJ. Author response: Electron tomography visualization of HIV-1 fusion with target cells using fusion inhibitors to trap the pre-hairpin intermediate Elife. DOI: 10.7554/Elife.58411.Sa2 |
0.424 |
|
2019 |
Fulcher JM, Petersen ME, Giesler RJ, Cruz ZS, Eckert DM, Francis JN, Kawamoto EM, Jacobsen MT, Kay MS. Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag. Organic & Biomolecular Chemistry. PMID 31793605 DOI: 10.1039/C9Ob02012H |
0.701 |
|
2019 |
Smith AR, Weinstock MT, Siglin AE, Whitby FG, Francis JN, Hill CP, Eckert DM, Root MJ, Kay MS. Characterization of resistance to a potent D-peptide HIV entry inhibitor. Retrovirology. 16: 28. PMID 31640718 DOI: 10.1186/S12977-019-0489-7 |
0.767 |
|
2019 |
Han H, Fulcher JM, Dandey VP, Iwasa JH, Sundquist WI, Kay MS, Shen PS, Hill CP. Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases. Elife. 8. PMID 31184588 DOI: 10.7554/Elife.44071 |
0.475 |
|
2019 |
Han H, Fulcher JM, Dandey VP, Iwasa JH, Sundquist WI, Kay MS, Shen PS, Hill CP. Author response: Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases Elife. DOI: 10.7554/Elife.44071.061 |
0.439 |
|
2018 |
Disotuar MM, Petersen ME, Nogueira JM, Kay MS, Chou DH. Synthesis of hydrophobic insulin-based peptides using a helping hand strategy. Organic & Biomolecular Chemistry. PMID 29947407 DOI: 10.1039/C8Ob01212A |
0.411 |
|
2018 |
Redman JS, Francis JN, Marquardt R, Papac D, Mueller AL, Eckert DM, Welch BD, Kay MS. Pharmacokinetic and chemical synthesis optimization of a potent D-peptide HIV entry inhibitor suitable for extended-release delivery. Molecular Pharmaceutics. PMID 29436835 DOI: 10.1021/Acs.Molpharmaceut.7B01004 |
0.757 |
|
2017 |
Jacobsen MT, Erickson PW, Kay MS. Aligator: A computational tool for optimizing total chemical synthesis of large proteins. Bioorganic & Medicinal Chemistry. PMID 28651912 DOI: 10.1016/J.Bmc.2017.05.061 |
0.383 |
|
2016 |
Jacobsen MT, Petersen ME, Ye X, Galibert M, Lorimer GH, Aucagne V, Kay MS. A Helping Hand to Overcome Solubility Challenges in Chemical Protein Synthesis. Journal of the American Chemical Society. PMID 27532670 DOI: 10.1021/Jacs.6B05719 |
0.506 |
|
2016 |
Petersen ME, Jacobsen MT, Kay MS. Synthesis of tumor necrosis factor α for use as a mirror-image phage display target. Organic & Biomolecular Chemistry. PMID 27211891 DOI: 10.1039/C6Ob00824K |
0.428 |
|
2015 |
Clinton TR, Weinstock MT, Jacobsen MT, Szabo-Fresnais N, Pandya MJ, Whitby FG, Herbert AS, Prugar LI, McKinnon R, Hill CP, Welch BD, Dye JM, Eckert DM, Kay MS. Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets. Protein Science : a Publication of the Protein Society. 24: 446-63. PMID 25287718 DOI: 10.1002/Pro.2578 |
0.507 |
|
2014 |
Weinstock MT, Jacobsen MT, Kay MS. Synthesis and folding of a mirror-image enzyme reveals ambidextrous chaperone activity. Proceedings of the National Academy of Sciences of the United States of America. 111: 11679-84. PMID 25071217 DOI: 10.1073/Pnas.1410900111 |
0.354 |
|
2013 |
Mesquita PM, Srinivasan P, Johnson TJ, Rastogi R, Evans-Strickfaden T, Kay MS, Buckheit KW, Buckheit RW, Smith JM, Kiser PF, Herold BC. Novel preclinical models of topical PrEP pharmacodynamics provide rationale for combination of drugs with complementary properties. Retrovirology. 10: 113. PMID 24156604 DOI: 10.1186/1742-4690-10-113 |
0.396 |
|
2013 |
Pang HB, Hevroni L, Kol N, Eckert DM, Tsvitov M, Kay MS, Rousso I. Virion stiffness regulates immature HIV-1 entry. Retrovirology. 10: 4. PMID 23305456 DOI: 10.1186/1742-4690-10-4 |
0.608 |
|
2013 |
Siglin AE, Francis N, Kay MS, Root MJ. Evolution of HIV-1 Resistance to a Cholesterol-Linked D-Peptide Fusion Inhibitor Biophysical Journal. 104: 90a. DOI: 10.1016/J.Bpj.2012.11.539 |
0.562 |
|
2012 |
Weinstock MT, Francis JN, Redman JS, Kay MS. Protease-resistant peptide design-empowering nature's fragile warriors against HIV. Biopolymers. 98: 431-42. PMID 23203688 DOI: 10.1002/Bip.22073 |
0.755 |
|
2012 |
Francis JN, Redman JS, Eckert DM, Kay MS. Design of a modular tetrameric scaffold for the synthesis of membrane-localized D-peptide inhibitors of HIV-1 entry. Bioconjugate Chemistry. 23: 1252-8. PMID 22545664 DOI: 10.1021/Bc300076F |
0.765 |
|
2011 |
Denton PW, Othieno F, Martinez-Torres F, Zou W, Krisko JF, Fleming E, Zein S, Powell DA, Wahl A, Kwak YT, Welch BD, Kay MS, Payne DA, Gallay P, Appella E, et al. One percent tenofovir applied topically to humanized BLT mice and used according to the CAPRISA 004 experimental design demonstrates partial protection from vaginal HIV infection, validating the BLT model for evaluation of new microbicide candidates. Journal of Virology. 85: 7582-93. PMID 21593172 DOI: 10.1128/Jvi.00537-11 |
0.559 |
|
2010 |
Welch BD, Francis JN, Redman JS, Paul S, Weinstock MT, Reeves JD, Lie YS, Whitby FG, Eckert DM, Hill CP, Root MJ, Kay MS. Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance. Journal of Virology. 84: 11235-44. PMID 20719956 DOI: 10.1128/Jvi.01339-10 |
0.774 |
|
2010 |
Kol N, Tsvitov M, Hevroni L, Wolf SG, Pang HB, Kay MS, Rousso I. The effect of purification method on the completeness of the immature HIV-1 Gag shell. Journal of Virological Methods. 169: 244-7. PMID 20691213 DOI: 10.1016/J.Jviromet.2010.07.035 |
0.632 |
|
2008 |
Eckert DM, Shi Y, Kim S, Welch BD, Kang E, Poff ES, Kay MS. Characterization of the steric defense of the HIV-1 gp41 N-trimer region. Protein Science : a Publication of the Protein Society. 17: 2091-100. PMID 18802030 DOI: 10.1110/Ps.038273.108 |
0.446 |
|
2008 |
De Domenico I, Nemeth E, Nelson JM, Phillips JD, Ajioka RS, Kay MS, Kushner JP, Ganz T, Ward DM, Kaplan J. The hepcidin-binding site on ferroportin is evolutionarily conserved. Cell Metabolism. 8: 146-56. PMID 18680715 DOI: 10.1016/J.Cmet.2008.07.002 |
0.346 |
|
2008 |
Kim S, Pang HB, Kay MS. Peptide mimic of the HIV envelope gp120-gp41 interface. Journal of Molecular Biology. 376: 786-97. PMID 18178220 DOI: 10.1016/J.Jmb.2007.12.001 |
0.585 |
|
2007 |
Welch BD, VanDemark AP, Heroux A, Hill CP, Kay MS. Potent D-peptide inhibitors of HIV-1 entry. Proceedings of the National Academy of Sciences of the United States of America. 104: 16828-33. PMID 17942675 DOI: 10.1073/Pnas.0708109104 |
0.679 |
|
2007 |
Kol N, Shi Y, Tsvitov M, Barlam D, Shneck RZ, Kay MS, Rousso I. A stiffness switch in human immunodeficiency virus. Biophysical Journal. 92: 1777-83. PMID 17158573 DOI: 10.1529/Biophysj.106.093914 |
0.396 |
|
2005 |
Stephens OM, Kim S, Welch BD, Hodsdon ME, Kay MS, Schepartz A. Inhibiting HIV fusion with a beta-peptide foldamer. Journal of the American Chemical Society. 127: 13126-7. PMID 16173723 DOI: 10.1021/Ja053444+ |
0.619 |
|
2005 |
Hamburger AE, Kim S, Welch BD, Kay MS. Steric accessibility of the HIV-1 gp41 N-trimer region. The Journal of Biological Chemistry. 280: 12567-72. PMID 15657041 DOI: 10.1074/Jbc.M412770200 |
0.532 |
|
2003 |
Kay MS. Silent, but deadly--eliminating reservoirs of latent HIV. Trends in Biotechnology. 21: 420-3. PMID 14512225 DOI: 10.1016/J.Tibtech.2003.08.004 |
0.502 |
|
2001 |
Root MJ, Kay MS, Kim PS. Protein design of an HIV-1 entry inhibitor Science. 291: 884-888. PMID 11229405 DOI: 10.1126/Science.1057453 |
0.626 |
|
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