Edward M. De Robertis - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 

159/261 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Azbazdar Y, Pera EM, De Robertis EM. Head organizer: Cerberus and IGF cooperate in brain induction in Xenopus embryos. Cells & Development. 203897. PMID 38109998 DOI: 10.1016/j.cdev.2023.203897  0.767
2023 Azbazdar Y, De Robertis EM. The early dorsal signal in vertebrate embryos requires endolysosomal membrane trafficking. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2300179. PMID 37983969 DOI: 10.1002/bies.202300179  0.336
2023 Azbazdar Y, Tejeda-Munoz N, Monka JC, Dayrit A, Binder G, Ozhan G, De Robertis EM. Addition of exogenous diacylglycerol enhances Wnt/β-catenin signaling through stimulation of macropinocytosis. Iscience. 26: 108075. PMID 37860772 DOI: 10.1016/j.isci.2023.108075  0.355
2023 Tejeda-Muñoz N, Azbazdar Y, Monka J, Binder G, Dayrit A, Ayala R, O'Brien N, De Robertis EM. The PMA Phorbol Ester Tumor Promoter Increases Canonical Wnt Signaling Via Macropinocytosis. Biorxiv : the Preprint Server For Biology. PMID 37333286 DOI: 10.1101/2023.06.02.543509  0.323
2022 Tejeda-Muñoz N, De Robertis EM. Lysosomes are required for early dorsal signaling in the embryo. Proceedings of the National Academy of Sciences of the United States of America. 119: e2201008119. PMID 35446621 DOI: 10.1073/pnas.2201008119  0.384
2022 Tejeda-Muñoz N, Morselli M, Moriyama Y, Sheladiya P, Pellegrini M, De Robertis EM. Canonical Wnt signaling induces focal adhesion and Integrin beta-1 endocytosis. Iscience. 25: 104123. PMID 35402867 DOI: 10.1016/j.isci.2022.104123  0.365
2022 Tejeda-Muñoz N, De Robertis EM. Wnt, GSK3, and Macropinocytosis. Sub-Cellular Biochemistry. 98: 169-187. PMID 35378708 DOI: 10.1007/978-3-030-94004-1_9  0.363
2021 Albrecht LV, Tejeda-Muñoz N, De Robertis EM. Cell Biology of Canonical Wnt Signaling. Annual Review of Cell and Developmental Biology. PMID 34196570 DOI: 10.1146/annurev-cellbio-120319-023657  0.365
2021 Zhang F, Zhu X, Wang P, He Q, Huang H, Zheng T, Li Y, Jia H, Xu L, Zhao H, Colozza G, Tao Q, De Robertis EM, Ding Y. The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in . Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33975953 DOI: 10.1073/pnas.2100342118  0.448
2021 De Robertis EM, Gurdon JB. A Brief History of in Biology. Cold Spring Harbor Protocols. PMID 33785561 DOI: 10.1101/pdb.top107615  0.532
2020 Colozza G, Jami-Alahmadi Y, Dsouza A, Tejeda-Muñoz N, Albrecht LV, Sosa EA, Wohlschlegel JA, De Robertis EM. Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway. Scientific Reports. 10: 21555. PMID 33299006 DOI: 10.1038/s41598-020-78019-5  0.385
2020 Colozza G, De Robertis EM. Dact-4 is a Xenopus laevis Spemann organizer gene related to the Dapper/Frodo antagonist of β-catenin family of proteins. Gene Expression Patterns : Gep. 38: 119153. PMID 33186756 DOI: 10.1016/j.gep.2020.119153  0.328
2020 Albrecht LV, Tejeda-Muñoz N, Bui MH, Cicchetto AC, Di Biagio D, Colozza G, Schmid E, Piccolo S, Christofk HR, De Robertis EM. GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery. Cell Reports. 32: 107973. PMID 32726636 DOI: 10.1016/J.Celrep.2020.107973  0.602
2019 Sosa EA, Moriyama Y, Ding Y, Tejeda-Muñoz N, Colozza G, De Robertis EM. Transcriptome analysis of regeneration during Xenopus laevis experimental twinning. The International Journal of Developmental Biology. 63: 301-309. PMID 31250914 DOI: 10.1387/ijdb.190006ed  0.323
2019 Tejeda-Muñoz N, Albrecht LV, Bui MH, De Robertis EM. Wnt canonical pathway activates macropinocytosis and lysosomal degradation of extracellular proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 31061124 DOI: 10.1073/pnas.1903506116  0.366
2018 Ding Y, Colozza G, Sosa EA, Moriyama Y, Rundle S, Salwinski L, De Robertis EM. Bighead is a Wnt antagonist secreted by the Spemann organizer that promotes Lrp6 endocytosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30209221 DOI: 10.1073/pnas.1812117115  0.451
2018 Albrecht LV, Ploper D, Tejeda-Muñoz N, De Robertis EM. Arginine methylation is required for canonical Wnt signaling and endolysosomal trafficking. Proceedings of the National Academy of Sciences of the United States of America. PMID 29773710 DOI: 10.1073/pnas.1804091115  0.341
2017 Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C. Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. Developmental Cell. 43: 71-82.e6. PMID 29017031 DOI: 10.1016/J.Devcel.2017.09.011  0.618
2017 De Robertis EM, Moriyama Y, Colozza G. Generation of animal form by the Chordin/Tolloid/BMP gradient: 100 years after D'Arcy Thompson. Development, Growth & Differentiation. PMID 28815565 DOI: 10.1111/dgd.12388  0.327
2017 Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MD, Zhang K, Merkurjev D, De Robertis EM. Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28348214 DOI: 10.1073/pnas.1700766114  0.339
2016 Ding Y, Colozza G, Zhang K, Moriyama Y, Ploper D, Sosa EA, Benitez MD, De Robertis EM. Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula. Developmental Biology. PMID 27016259 DOI: 10.1016/j.ydbio.2016.02.032  0.305
2015 De Robertis EM, Ploper D. Sperm Motility Requires Wnt/GSK3 Stabilization of Proteins. Developmental Cell. 35: 401-402. PMID 26609954 DOI: 10.1016/j.devcel.2015.11.009  0.349
2015 Blum M, De Robertis EM, Wallingford JB, Niehrs C. Morpholinos: Antisense and Sensibility. Developmental Cell. 35: 145-9. PMID 26506304 DOI: 10.1016/J.Devcel.2015.09.017  0.66
2015 Bier E, De Robertis EM. BMP gradients: A paradigm for morphogen-mediated developmental patterning Science. 348. PMID 26113727 DOI: 10.1126/science.aaa5838  0.364
2015 Kim H, Vick P, Hedtke J, Ploper D, De Robertis EM. Wnt Signaling Translocates Lys48-Linked Polyubiquitinated Proteins to the Lysosomal Pathway. Cell Reports. 11: 1151-9. PMID 26004177 DOI: 10.1016/j.celrep.2015.04.048  0.324
2015 Ploper D, De Robertis EM. The MITF family of transcription factors: Role in endolysosomal biogenesis, Wnt signaling, and oncogenesis. Pharmacological Research. 99: 36-43. PMID 26003288 DOI: 10.1016/j.phrs.2015.04.006  0.352
2015 Ploper D, Taelman VF, Robert L, Perez BS, Titz B, Chen HW, Graeber TG, von Euw E, Ribas A, De Robertis EM. MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells. Proceedings of the National Academy of Sciences of the United States of America. 112: E420-9. PMID 25605940 DOI: 10.1073/pnas.1424576112  0.408
2015 Kim H, Vick P, Hedtke J, Ploper D, De Robertis EM. Wnt Signaling Translocates Lys48-Linked Polyubiquitinated Proteins to the Lysosomal Pathway Cell Reports. 11: 1151-1159. DOI: 10.1016/j.celrep.2015.04.048  0.336
2014 Demagny H, Araki T, De Robertis EM. The tumor suppressor Smad4/DPC4 is regulated by phosphorylations that integrate FGF, Wnt, and TGF-β signaling. Cell Reports. 9: 688-700. PMID 25373906 DOI: 10.1016/j.celrep.2014.09.020  0.324
2014 De Robertis EM, Niehrs C. Herbert Steinbeisser: a life with the Xenopus embryo. The International Journal of Developmental Biology. 58: 299-302. PMID 25354448 DOI: 10.1387/Ijdb.140117Ed  0.45
2014 Colozza G, De Robertis EM. Maternal syntabulin is required for dorsal axis formation and is a germ plasm component in Xenopus. Differentiation; Research in Biological Diversity. 88: 17-26. PMID 24798204 DOI: 10.1016/j.diff.2014.03.002  0.353
2013 Plouhinec JL, Zakin L, Moriyama Y, De Robertis EM. Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo. Proceedings of the National Academy of Sciences of the United States of America. 110: 20372-9. PMID 24284174 DOI: 10.1073/pnas.1319745110  0.382
2012 Dobrowolski R, Vick P, Ploper D, Gumper I, Snitkin H, Sabatini DD, De Robertis EM. Presenilin deficiency or lysosomal inhibition enhances Wnt signaling through relocalization of GSK3 to the late-endosomal compartment. Cell Reports. 2: 1316-28. PMID 23122960 DOI: 10.1016/J.Celrep.2012.09.026  0.38
2012 Dobrowolski R, De Robertis EM. Endocytic control of growth factor signalling: multivesicular bodies as signalling organelles. Nature Reviews. Molecular Cell Biology. 13: 53-60. PMID 22108513 DOI: 10.1038/nrm3244  0.33
2011 Eivers E, Demagny H, Choi RH, De Robertis EM. Phosphorylation of Mad controls competition between wingless and BMP signaling. Science Signaling. 4: ra68. PMID 21990430 DOI: 10.1126/scisignal.2002034  0.395
2011 Vorwald-Denholtz PP, De Robertis EM. Temporal pattern of the posterior expression of Wingless in Drosophila blastoderm. Gene Expression Patterns : Gep. 11: 456-63. PMID 21821151 DOI: 10.1016/j.gep.2011.07.004  0.314
2011 Ploper D, Lee HX, De Robertis EM. Dorsal-ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases. Developmental Biology. 352: 317-28. PMID 21295563 DOI: 10.1016/j.ydbio.2011.01.029  0.631
2011 De Robertis EM, VanHook AM. Science Signaling Podcast: 11 October 2011 Science Signaling. 4: pc21-pc21. DOI: 10.1126/Scisignal.2002559  0.311
2010 Taelman VF, Dobrowolski R, Plouhinec JL, Fuentealba LC, Vorwald PP, Gumper I, Sabatini DD, De Robertis EM. Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes. Cell. 143: 1136-48. PMID 21183076 DOI: 10.1016/J.Cell.2010.11.034  0.812
2010 Zakin L, Chang EY, Plouhinec JL, De Robertis EM. Crossveinless-2 is required for the relocalization of Chordin protein within the vertebral field in mouse embryos. Developmental Biology. 347: 204-15. PMID 20807528 DOI: 10.1016/j.ydbio.2010.08.025  0.336
2010 De Robertis EM. Wnt signaling in axial patterning and regeneration: lessons from planaria. Science Signaling. 3: pe21. PMID 20571126 DOI: 10.1126/scisignal.3127pe21  0.383
2010 Sander V, Eivers E, Choi RH, De Robertis EM. Drosophila Smad2 opposes Mad signaling during wing vein development. Plos One. 5: e10383. PMID 20442782 DOI: 10.1371/journal.pone.0010383  0.423
2010 Tran U, Zakin L, Schweickert A, Agrawal R, Döger R, Blum M, De Robertis EM, Wessely O. The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity. Development (Cambridge, England). 137: 1107-16. PMID 20215348 DOI: 10.1242/Dev.046045  0.592
2010 Fuentealba LC, Eivers E, Lee HX, De Robertis EM. Integration of BMP, RTK, and wnt signaling through smad1 phosphorylations Handbook of Cell Signaling, 2/E. 2: 1989-1994. DOI: 10.1016/B978-0-12-374145-5.00243-6  0.786
2009 Plouhinec JL, De Robertis EM. Systems biology of the self-regulating morphogenetic gradient of the Xenopus gastrula. Cold Spring Harbor Perspectives in Biology. 1: a001701. PMID 20066084 DOI: 10.1101/cshperspect.a001701  0.395
2009 Eivers E, Demagny H, De Robertis EM. Integration of BMP and Wnt signaling via vertebrate Smad1/5/8 and Drosophila Mad. Cytokine & Growth Factor Reviews. 20: 357-65. PMID 19896409 DOI: 10.1016/j.cytogfr.2009.10.017  0.376
2009 Lee HX, Mendes FA, Plouhinec JL, De Robertis EM. Enzymatic regulation of pattern: BMP4 binds CUB domains of Tolloids and inhibits proteinase activity. Genes & Development. 23: 2551-62. PMID 19884260 DOI: 10.1101/gad.1839309  0.598
2009 De Robertis EM. Spemann's organizer and the self-regulation of embryonic fields. Mechanisms of Development. 126: 925-41. PMID 19733655 DOI: 10.1016/j.mod.2009.08.004  0.408
2009 Eivers E, Fuentealba LC, Sander V, Clemens JC, Hartnett L, De Robertis EM. Mad is required for wingless signaling in wing development and segment patterning in Drosophila. Plos One. 4: e6543. PMID 19657393 DOI: 10.1371/Journal.Pone.0006543  0.778
2008 Zakin L, Metzinger CA, Chang EY, Coffinier C, De Robertis EM. Development of the vertebral morphogenetic field in the mouse: interactions between Crossveinless-2 and Twisted Gastrulation. Developmental Biology. 323: 6-18. PMID 18789316 DOI: 10.1016/j.ydbio.2008.08.019  0.33
2008 Ambrosio AL, Taelman VF, Lee HX, Metzinger CA, Coffinier C, De Robertis EM. Crossveinless-2 Is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning. Developmental Cell. 15: 248-60. PMID 18694564 DOI: 10.1016/j.devcel.2008.06.013  0.619
2008 Eivers E, Fuentealba LC, De Robertis EM. Integrating positional information at the level of Smad1/5/8. Current Opinion in Genetics & Development. 18: 304-10. PMID 18590818 DOI: 10.1016/J.Gde.2008.06.001  0.781
2008 Fuentealba LC, Eivers E, Geissert D, Taelman V, De Robertis EM. Asymmetric mitosis: Unequal segregation of proteins destined for degradation. Proceedings of the National Academy of Sciences of the United States of America. 105: 7732-7. PMID 18511557 DOI: 10.1073/Pnas.0803027105  0.757
2008 Ishibashi H, Matsumura N, Hanafusa H, Matsumoto K, De Robertis EM, Kuroda H. Expression of Siamois and Twin in the blastula Chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos. Mechanisms of Development. 125: 58-66. PMID 18036787 DOI: 10.1016/J.Mod.2007.10.005  0.729
2007 Fuentealba LC, Eivers E, Ikeda A, Hurtado C, Kuroda H, Pera EM, De Robertis EM. Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal. Cell. 131: 980-93. PMID 18045539 DOI: 10.1016/J.Cell.2007.09.027  0.814
2007 Sander V, Reversade B, De Robertis EM. The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning. The Embo Journal. 26: 2955-65. PMID 17525737 DOI: 10.1038/Sj.Emboj.7601705  0.613
2006 De Robertis EM. Spemann's organizer and self-regulation in amphibian embryos. Nature Reviews. Molecular Cell Biology. 7: 296-302. PMID 16482093 DOI: 10.1038/nrm1855  0.374
2006 Lee HX, Ambrosio AL, Reversade B, De Robertis EM. Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases. Cell. 124: 147-59. PMID 16413488 DOI: 10.1016/J.Cell.2005.12.018  0.714
2005 Reversade B, De Robertis EM. Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field. Cell. 123: 1147-60. PMID 16360041 DOI: 10.1016/J.Cell.2005.08.047  0.646
2005 Pera EM, Hou S, Strate I, Wessely O, De Robertis EM. Exploration of the extracellular space by a large-scale secretion screen in the early Xenopus embryo. The International Journal of Developmental Biology. 49: 781-96. PMID 16172975 DOI: 10.1387/ijdb.052003ep  0.742
2005 Reversade B, Kuroda H, Lee H, Mays A, De Robertis EM. Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos. Development (Cambridge, England). 132: 3381-92. PMID 15975940 DOI: 10.1242/Dev.01901  0.821
2005 Wessely O, Kim JI, Tran U, Fuentealba L, De Robertis EM. xBtg-x regulates Wnt/beta-Catenin signaling during early Xenopus development. Developmental Biology. 283: 17-28. PMID 15975429 DOI: 10.1016/J.Ydbio.2005.03.033  0.776
2005 Kuroda H, Fuentealba L, Ikeda A, Reversade B, De Robertis EM. Default neural induction: neuralization of dissociated Xenopus cells is mediated by Ras/MAPK activation. Genes & Development. 19: 1022-7. PMID 15879552 DOI: 10.1101/Gad.1306605  0.797
2005 Zakin L, Reversade B, Kuroda H, Lyons KM, De Robertis EM. Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. Development (Cambridge, England). 132: 2489-99. PMID 15843411 DOI: 10.1242/Dev.01822  0.778
2004 De Robertis EM, Kuroda H. Dorsal-ventral patterning and neural induction in Xenopus embryos. Annual Review of Cell and Developmental Biology. 20: 285-308. PMID 15473842 DOI: 10.1146/Annurev.Cellbio.20.011403.154124  0.751
2004 Kuroda H, Wessely O, De Robertis EM. Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus. Plos Biology. 2: E92. PMID 15138495 DOI: 10.1371/Journal.Pbio.0020092  0.733
2004 Wessely O, Kim JI, Geissert D, Tran U, De Robertis EM. Analysis of Spemann organizer formation in Xenopus embryos by cDNA macroarrays. Developmental Biology. 269: 552-66. PMID 15110719 DOI: 10.1016/j.ydbio.2004.01.018  0.425
2004 Oelgeschläger M, Tran U, Grubisic K, De Robertis EM. Identification of a second Xenopus twisted gastrulation gene. The International Journal of Developmental Biology. 48: 57-61. PMID 15005575 DOI: 10.1387/ijdb.15005575  0.376
2004 Zakin L, De Robertis EM. Inactivation of mouse Twisted gastrulation reveals its role in promoting Bmp4 activity during forebrain development. Development (Cambridge, England). 131: 413-24. PMID 14681194 DOI: 10.1242/dev.00946  0.382
2003 Pera EM, Ikeda A, Eivers E, De Robertis EM. Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. Genes & Development. 17: 3023-8. PMID 14701872 DOI: 10.1101/gad.1153603  0.77
2003 Oelgeschläger M, Reversade B, Larraín J, Little S, Mullins MC, De Robertis EM. The pro-BMP activity of Twisted gastrulation is independent of BMP binding. Development (Cambridge, England). 130: 4047-56. PMID 12874126 DOI: 10.1242/Dev.00633  0.626
2003 Bachiller D, Klingensmith J, Shneyder N, Tran U, Anderson R, Rossant J, De Robertis EM. The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome. Development (Cambridge, England). 130: 3567-78. PMID 12810603 DOI: 10.1242/Dev.00581  0.349
2003 Pera EM, Martinez SL, Flanagan JJ, Brechner M, Wessely O, De Robertis EM. Darmin is a novel secreted protein expressed during endoderm development in Xenopus. Gene Expression Patterns : Gep. 3: 147-52. PMID 12711541 DOI: 10.1016/S1567-133X(03)00011-5  0.751
2003 Oelgeschläger M, Kuroda H, Reversade B, De Robertis EM. Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos. Developmental Cell. 4: 219-30. PMID 12586065 DOI: 10.1016/S1534-5807(02)00404-5  0.744
2002 Coffinier C, Ketpura N, Tran U, Geissert D, De Robertis EM. Mouse Crossveinless-2 is the vertebrate homolog of a Drosophila extracellular regulator of BMP signaling. Mechanisms of Development. 119: S179-84. PMID 14516682 DOI: 10.1016/S0925-4773(03)00113-8  0.823
2002 Coffinier C, Ketpura N, Tran U, Geissert D, De Robertis EM. Mouse Crossveinless-2 is the vertebrate homolog of a Drosophila extracellular regulator of BMP signaling. Gene Expression Patterns : Gep. 2: 189-94. PMID 12617799 DOI: 10.1016/S0925-4773(02)00420-3  0.823
2002 Abreu JG, Ketpura NI, Reversade B, De Robertis EM. Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta. Nature Cell Biology. 4: 599-604. PMID 12134160 DOI: 10.1038/Ncb826  0.779
2002 Pera EM, Kim JI, Martinez SL, Brechner M, Li SY, Wessely O, De Robertis EM. Isthmin is a novel secreted protein expressed as part of the Fgf-8 synexpression group in the Xenopus midbrain-hindbrain organizer. Mechanisms of Development. 116: 169-72. PMID 12128218 DOI: 10.1016/S0925-4773(02)00123-5  0.767
2002 Garcia Abreu J, Coffinier C, Larraín J, Oelgeschläger M, De Robertis EM. Chordin-like CR domains and the regulation of evolutionarily conserved extracellular signaling systems. Gene. 287: 39-47. PMID 11992721 DOI: 10.1016/S0378-1119(01)00827-7  0.33
2001 Larraín J, Oelgeschläger M, Ketpura NI, Reversade B, Zakin L, De Robertis EM. Proteolytic cleavage of Chordin as a switch for the dual activities of Twisted gastrulation in BMP signaling. Development (Cambridge, England). 128: 4439-47. PMID 11714670  0.826
2001 Pera EM, Wessely O, Li SY, De Robertis EM. Neural and head induction by insulin-like growth factor signals. Developmental Cell. 1: 655-65. PMID 11709186 DOI: 10.1016/S1534-5807(01)00069-7  0.761
2001 Wessely O, Agius E, Oelgeschläger M, Pera EM, De Robertis EM. Neural induction in the absence of mesoderm: beta-catenin-dependent expression of secreted BMP antagonists at the blastula stage in Xenopus. Developmental Biology. 234: 161-73. PMID 11356027 DOI: 10.1006/dbio.2001.0258  0.772
2001 De Robertis EM, Wessely O, Oelgeschläger M, Brizuela B, Pera E, Larraín J, Abreu J, Bachiller D. Molecular mechanisms of cell-cell signaling by the Spemann-Mangold organizer. The International Journal of Developmental Biology. 45: 189-97. PMID 11291846  0.346
2001 Wessely O, Tran U, Zakin L, De Robertis EM. Identification and expression of the mammalian homologue of Bicaudal-C. Mechanisms of Development. 101: 267-70. PMID 11231089 DOI: 10.1016/S0925-4773(00)00568-2  0.301
2001 Coffinier C, Tran U, Larraín J, De Robertis EM. Neuralin-1 is a novel Chordin-related molecule expressed in the mouse neural plate. Mechanisms of Development. 100: 119-22. PMID 11118896 DOI: 10.1016/S0925-4773(00)00507-4  0.346
2000 De Robertis EM, Larraín J, Oelgeschläger M, Wessely O. The establishment of Spemann's organizer and patterning of the vertebrate embryo. Nature Reviews. Genetics. 1: 171-81. PMID 11252746 DOI: 10.1038/35042039  0.352
2000 Pera EM, De Robertis EM. A direct screen for secreted proteins in Xenopus embryos identifies distinct activities for the Wnt antagonists Crescent and Frzb-1. Mechanisms of Development. 96: 183-95. PMID 10960783 DOI: 10.1016/S0925-4773(00)00394-4  0.776
2000 Oelgeschläger M, Larraín J, Geissert D, De Robertis EM. The evolutionarily conserved BMP-binding protein Twisted gastrulation promotes BMP signalling. Nature. 405: 757-63. PMID 10866189 DOI: 10.1038/35015500  0.438
2000 Belo JA, Bachiller D, Agius E, Kemp C, Borges AC, Marques S, Piccolo S, De Robertis EM. Cerberus-like is a secreted BMP and nodal antagonist not essential for mouse development. Genesis (New York, N.Y. : 2000). 26: 265-70. PMID 10748465 DOI: 10.1002/(Sici)1526-968X(200004)26:4<265::Aid-Gene80>3.0.Co;2-4  0.6
2000 Agius E, Oelgeschläger M, Wessely O, Kemp C, De Robertis EM. Endodermal Nodal-related signals and mesoderm induction in Xenopus. Development (Cambridge, England). 127: 1173-83. PMID 10683171  0.39
1999 Konishi Y, Tominaga M, Watanabe Y, Imamura F, Goldfarb A, Maki R, Blum M, De Robertis EM, Tominaga A. GOOSECOID inhibits erythrocyte differentiation by competing with Rb for PU.1 binding in murine cells. Oncogene. 18: 6795-805. PMID 10597288 DOI: 10.1038/Sj.Onc.1203118  0.62
1999 Duprez D, Leyns L, Bonnin MA, Lapointe F, Etchevers H, De Robertis EM, Le Douarin N. Expression of Frzb-1 during chick development. Mechanisms of Development. 89: 179-83. PMID 10559495 DOI: 10.1016/S0925-4773(99)00206-3  0.302
1999 Borello U, Coletta M, Tajbakhsh S, Leyns L, De Robertis EM, Buckingham M, Cossu G. Transplacental delivery of the Wnt antagonist Frzb1 inhibits development of caudal paraxial mesoderm and skeletal myogenesis in mouse embryos. Development (Cambridge, England). 126: 4247-55. PMID 10477293  0.387
1999 Piccolo S, Agius E, Leyns L, Bhattacharyya S, Grunz H, Bouwmeester T, De Robertis EM. The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals. Nature. 397: 707-10. PMID 10067895 DOI: 10.1038/17820  0.69
1998 Yamamoto A, Amacher SL, Kim SH, Geissert D, Kimmel CB, De Robertis EM. Zebrafish paraxial protocadherin is a downstream target of spadetail involved in morphogenesis of gastrula mesoderm. Development (Cambridge, England). 125: 3389-97. PMID 9693142  0.307
1998 Blumberg B, Kang H, Bolado J, Chen H, Craig AG, Moreno TA, Umesono K, Perlmann T, De Robertis EM, Evans RM. BXR, an embryonic orphan nuclear receptor activated by a novel class of endogenous benzoate metabolites. Genes & Development. 12: 1269-77. PMID 9573044 DOI: 10.1101/Gad.12.9.1269  0.617
1998 Belo JA, Leyns L, Yamada G, De Robertis EM. The prechordal midline of the chondrocranium is defective in Goosecoid-1 mouse mutants. Mechanisms of Development. 72: 15-25. PMID 9533949 DOI: 10.1016/S0925-4773(97)00204-9  0.323
1998 Pillemer G, Epstein M, Blumberg B, Yisraeli JK, De Robertis EM, Steinbeisser H, Fainsod A. Nested expression and sequential downregulation of the Xenopus caudal genes along the anterior-posterior axis. Mechanisms of Development. 71: 193-6. PMID 9507125 DOI: 10.1016/S0925-4773(97)00193-7  0.676
1997 Heanue TA, Johnson RL, Izpisua-Belmonte JC, Stern CD, De Robertis EM, Tabin CJ. Goosecoid misexpression alters the morphology and Hox gene expression of the developing chick limb bud. Mechanisms of Development. 69: 31-7. PMID 9486529 DOI: 10.1016/S0925-4773(97)00149-4  0.311
1997 Belo JA, Bouwmeester T, Leyns L, Kertesz N, Gallo M, Follettie M, De Robertis EM. Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula. Mechanisms of Development. 68: 45-57. PMID 9431803 DOI: 10.1016/S0925-4773(97)00125-1  0.314
1997 Piccolo S, Agius E, Lu B, Goodman S, Dale L, De Robertis EM. Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity. Cell. 91: 407-16. PMID 9363949 DOI: 10.1016/S0092-8674(00)80424-9  0.632
1997 Pfeffer PL, De Robertis EM, Izpisua-Belmonte JC. Crescent, a novel chick gene encoding a Frizzled-like cysteine-rich domain, is expressed in anterior regions during early embryogenesis. The International Journal of Developmental Biology. 41: 449-58. PMID 9240561  0.313
1997 Leyns L, Bouwmeester T, Kim SH, Piccolo S, De Robertis EM. Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer. Cell. 88: 747-56. PMID 9118218 DOI: 10.1016/S0092-8674(00)81921-2  0.642
1997 Sasai Y, De Robertis EM. Ectodermal patterning in vertebrate embryos. Developmental Biology. 182: 5-20. PMID 9073437 DOI: 10.1006/dbio.1996.8445  0.54
1996 Sasai Y, Lu B, Piccolo S, De Robertis EM. Endoderm induction by the organizer-secreted factors chordin and noggin in Xenopus animal caps. The Embo Journal. 15: 4547-55. PMID 8887546 DOI: 10.1002/J.1460-2075.1996.Tb00832.X  0.706
1996 Bouwmeester T, Kim S, Sasai Y, Lu B, De Robertis EM. Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer. Nature. 382: 595-601. PMID 8757128 DOI: 10.1038/382595a0  0.504
1996 Holley SA, Neul JL, Attisano L, Wrana JL, Sasai Y, O'Connor MB, De Robertis EM, Ferguson EL. The Xenopus dorsalizing factor noggin ventralizes Drosophila embryos by preventing DPP from activating its receptor. Cell. 86: 607-17. PMID 8752215 DOI: 10.1016/S0092-8674(00)80134-8  0.574
1996 Piccolo S, Sasai Y, Lu B, De Robertis EM. Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4. Cell. 86: 589-98. PMID 8752213 DOI: 10.1016/S0092-8674(00)80132-4  0.709
1996 Gont LK, Fainsod A, Kim SH, De Robertis EM. Overexpression of the homeobox gene Xnot-2 leads to notochord formation in Xenopus. Developmental Biology. 174: 174-8. PMID 8626017 DOI: 10.1006/Dbio.1996.0061  0.704
1996 De Robertis EM, Sasai Y. A common plan for dorsoventral patterning in Bilateria. Nature. 380: 37-40. PMID 8598900 DOI: 10.1038/380037a0  0.518
1995 Sasai Y, Lu B, Steinbeisser H, De Robertis EM. Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature. 376: 333-6. PMID 7630399 DOI: 10.1038/376333a0  0.584
1995 Holley SA, Jackson PD, Sasai Y, Lu B, De Robertis EM, Hoffmann FM, Ferguson EL. A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin. Nature. 376: 249-53. PMID 7617035 DOI: 10.1038/376249a0  0.555
1995 Steinbeisser H, Fainsod A, Niehrs C, Sasai Y, De Robertis EM. The role of gsc and BMP-4 in dorsal-ventral patterning of the marginal zone in Xenopus: a loss-of-function study using antisense RNA. The Embo Journal. 14: 5230-43. PMID 7489713  0.536
1995 Sasal Y, Lu B, Steinbelsser H, De Robertis EM. Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature. 378: 419. PMID 7477384 DOI: 10.1038/378419a0  0.347
1995 Sasai Y, Lu B, Steinbeisser H, De Robertis EM. Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature. 377: 757. PMID 7477270 DOI: 10.1038/377757a0  0.544
1994 Sasai Y, Lu B, Steinbeisser H, Geissert D, Gont LK, De Robertis EM. Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell. 79: 779-90. PMID 8001117 DOI: 10.1016/0092-8674(94)90068-X  0.576
1994 Fainsod A, Steinbeisser H, De Robertis EM. On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo. The Embo Journal. 13: 5015-25. PMID 7957067  0.379
1994 Blum M, De Robertis EM, Kojis T, Heinzmann C, Klisak I, Geissert D, Sparkes RS. Molecular cloning of the human homeobox gene goosecoid (GSC) and mapping of the gene to human chromosome 14q32.1. Genomics. 21: 388-93. PMID 7916327 DOI: 10.1006/Geno.1994.1281  0.585
1994 Niehrs C, Steinbeisser H, De Robertis EM. Mesodermal patterning by a gradient of the vertebrate homeobox gene goosecoid. Science (New York, N.Y.). 263: 817-20. PMID 7905664 DOI: 10.1126/SCIENCE.7905664  0.559
1994 Schulte-Merker S, Hammerschmidt M, Beuchle D, Cho KW, De Robertis EM, Nüsslein-Volhard C. Expression of zebrafish goosecoid and no tail gene products in wild-type and mutant no tail embryos. Development (Cambridge, England). 120: 843-52. PMID 7600961  0.603
1993 Niehrs C, Keller R, Cho KW, De Robertis EM. The homeobox gene goosecoid controls cell migration in Xenopus embryos. Cell. 72: 491-503. PMID 8095000 DOI: 10.1016/0092-8674(93)90069-3  0.574
1993 Bittner D, De Robertis EM, Cho KW. Characterization of the Xenopus Hox 2.4 gene and identification of control elements in its intron. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 196: 11-24. PMID 7916675 DOI: 10.1002/aja.1001960103  0.334
1993 Steinbeisser H, De Robertis EM, Ku M, Kessler DS, Melton DA. Xenopus axis formation: induction of goosecoid by injected Xwnt-8 and activin mRNAs. Development (Cambridge, England). 118: 499-507. PMID 7900991  0.558
1993 Steinbeisser H, De Robertis EM. Xenopus goosecoid: a gene expressed in the prechordal plate that has dorsalizing activity. Comptes Rendus De L'Acadã©Mie Des Sciences. Sã©Rie Iii, Sciences De La Vie. 316: 959-71. PMID 7521271  0.339
1992 Niehrs C, De Robertis EM. Vertebrate axis formation. Current Opinion in Genetics & Development. 2: 550-5. PMID 1356042 DOI: 10.1016/S0959-437X(05)80170-4  0.553
1992 Blum M, Gaunt SJ, Cho KW, Steinbeisser H, Blumberg B, Bittner D, De Robertis EM. Gastrulation in the mouse: the role of the homeobox gene goosecoid. Cell. 69: 1097-106. PMID 1352187 DOI: 10.1016/0092-8674(92)90632-M  0.75
1992 Blumberg B, Mangelsdorf DJ, Dyck JA, Bittner DA, Evans RM, De Robertis EM. Multiple retinoid-responsive receptors in a single cell: families of retinoid "X" receptors and retinoic acid receptors in the Xenopus egg. Proceedings of the National Academy of Sciences of the United States of America. 89: 2321-5. PMID 1312717 DOI: 10.1073/Pnas.89.6.2321  0.625
1992 Jegalian BG, Miller RW, Wright CV, Blum M, De Robertis EM. A Hox 3.3-lacZ transgene expressed in developing limbs. Mechanisms of Development. 39: 171-80. PMID 1292571 DOI: 10.1016/0925-4773(92)90044-K  0.59
1991 Cho KW, Blumberg B, Steinbeisser H, De Robertis EM. Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid. Cell. 67: 1111-20. PMID 1684739 DOI: 10.1016/0092-8674(91)90288-A  0.597
1991 Blumberg B, Wright CV, De Robertis EM, Cho KW. Organizer-specific homeobox genes in Xenopus laevis embryos. Science (New York, N.Y.). 253: 194-6. PMID 1677215 DOI: 10.1126/Science.1677215  0.59
1990 Molven A, Wright CV, Bremiller R, De Robertis EM, Kimmel CB. Expression of a homeobox gene product in normal and mutant zebrafish embryos: evolution of the tetrapod body plan. Development (Cambridge, England). 109: 279-88. PMID 1976086  0.305
1989 Wright CV, Schnegelsberg P, De Robertis EM. XlHbox 8: a novel Xenopus homeo protein restricted to a narrow band of endoderm. Development (Cambridge, England). 105: 787-94. PMID 2574662  0.316
1989 Oliver G, Sidell N, Fiske W, Heinzmann C, Mohandas T, Sparkes RS, De Robertis EM. Complementary homeo protein gradients in developing limb buds. Genes & Development. 3: 641-50. PMID 2568311  0.315
1989 Wright CV, Cho KW, Oliver G, De Robertis EM. Vertebrate homeodomain proteins: families of region-specific transcription factors. Trends in Biochemical Sciences. 14: 52-6. PMID 2565051 DOI: 10.1016/0968-0004(89)90043-1  0.309
1988 Cho KW, Goetz J, Wright CV, Fritz A, Hardwicke J, De Robertis EM. Differential utilization of the same reading frame in a Xenopus homeobox gene encodes two related proteins sharing the same DNA-binding specificity. The Embo Journal. 7: 2139-49. PMID 2901347  0.312
1988 Oliver G, Wright CV, Hardwicke J, De Robertis EM. Differential antero-posterior expression of two proteins encoded by a homeobox gene in Xenopus and mouse embryos. The Embo Journal. 7: 3199-209. PMID 2460338  0.358
1987 Bürglin TR, Mattaj IW, Newmeyer DD, Zeller R, De Robertis EM. Cloning of nucleoplasmin from Xenopus laevis oocytes and analysis of its developmental expression. Genes & Development. 1: 97-107. PMID 3428591 DOI: 10.1101/Gad.1.1.97  0.722
1987 Bürglin TR, De Robertis EM. The nuclear migration signal of Xenopus laevis nucleoplasmin. The Embo Journal. 6: 2617-25. PMID 3119324  0.35
1987 Sharpe CR, Fritz A, De Robertis EM, Gurdon JB. A homeobox-containing marker of posterior neural differentiation shows the importance of predetermination in neural induction. Cell. 50: 749-58. PMID 2441873 DOI: 10.1016/0092-8674(87)90333-3  0.541
1985 Mattaj IW, De Robertis EM. Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins. Cell. 40: 111-8. PMID 2578319 DOI: 10.1016/0092-8674(85)90314-9  0.547
1985 Mattaj IW, Lienhard S, Jiricny J, De Robertis EM. An enhancer-like sequence within the Xenopus U2 gene promoter facilitates the formation of stable transcription complexes. Nature. 316: 163-7. PMID 2409453 DOI: 10.1038/316163a0  0.514
1984 Shepherd JC, McGinnis W, Carrasco AE, De Robertis EM, Gehring WJ. Fly and frog homoeo domains show homologies with yeast mating type regulatory proteins. Nature. 310: 70-1. PMID 6429549 DOI: 10.1038/310070a0  0.661
1984 Carrasco AE, McGinnis W, Gehring WJ, De Robertis EM. Cloning of an X. laevis gene expressed during early embryogenesis coding for a peptide region homologous to Drosophila homeotic genes. Cell. 37: 409-14. PMID 6327066 DOI: 10.1016/0092-8674(84)90371-4  0.67
1983 Zeller R, Nyffenegger T, De Robertis EM. Nucleocytoplasmic distribution of snRNPs and stockpiled snRNA-binding proteins during oogenesis and early development in Xenopus laevis. Cell. 32: 425-34. PMID 6186395 DOI: 10.1016/0092-8674(83)90462-2  0.611
1980 Melton DA, Cortese R, de Robertis EM, Trendelenburg MF, Gurdon JB. Gene injection into amphibian oocytes. Results and Problems in Cell Differentiation. 11: 8-14. PMID 7444205 DOI: 10.1007/978-3-540-38267-6_2  0.635
1980 Mills AD, Laskey RA, Black P, De Robertis EM. An acidic protein which assembles nucleosomes in vitro is the most abundant protein in Xenopus oocyte nuclei. Journal of Molecular Biology. 139: 561-8. PMID 7441745 DOI: 10.1016/0022-2836(80)90148-5  0.542
1980 Melton DA, De Robertis EM, Cortese R. Order and intracellular location of the events involved in the maturation of a spliced tRNA. Nature. 284: 143-8. PMID 6987526 DOI: 10.1038/284143a0  0.469
1979 De Robertis EM, Gurdon JB. Gene transplantation and the analysis of development. Scientific American. 241: 74-82. PMID 504982 DOI: 10.1038/Scientificamerican1279-74  0.429
1979 Gurdon JB, Laskey RA, De Robertis EM, Partington GA. Reprogramming of transplanted nuclei in amphibia. International Review of Cytology. Supplement. 161-78. PMID 385535  0.58
1979 Gurdon JB, Melton DA, De Robertis EM. Genetics in an oocyte. Ciba Foundation Symposium. 63-80. PMID 289482 DOI: 10.1002/9780470720486.ch5  0.594
1978 De Robertis EM, Longthorne RF, Gurdon JB. Intracellular migration of nuclear proteins in Xenopus oocytes. Nature. 272: 254-6. PMID 564468 DOI: 10.1038/272254A0  0.536
1978 De Robertis EM, Partington GA, Gurdon JB. Selective gene expression by somatic nuclei injected into amphibian oocytes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 283: 375-7. PMID 26084 DOI: 10.1098/Rstb.1978.0040  0.512
1978 Gurdon JB, Wyllie AH, De Robertis EM. The transcription and translation of DNA injected into oocytes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 283: 367-72. PMID 26082 DOI: 10.1098/Rstb.1978.0038  0.484
1977 De Robertis EM, Partington GA, Longthorne RF, Gurdon JB. Somatic nuclei in amphibian oocytes: evidence for selective gene expression. Journal of Embryology and Experimental Morphology. 40: 199-214. PMID 562385  0.529
1977 de Robertis EM, Gurdon JB, Partington GA, Mertz JE, Laskey RA. Injected amphibian oocytes: a living test tube for the study of eukaryotic gene transcription? Biochemical Society Symposium. 181-91. PMID 339919  0.763
1977 De Robertis EM, Gurdon JB. Gene activation in somatic nuclei after injection into amphibian oocytes. Proceedings of the National Academy of Sciences of the United States of America. 74: 2470-4. PMID 267940 DOI: 10.1073/Pnas.74.6.2470  0.526
1977 De Robertis EM, Mertz JE. Coupled transcription-translation of DNA injected into Xenopus oocytes. Cell. 12: 175-82. PMID 198138 DOI: 10.1016/0092-8674(77)90195-7  0.593
1976 Gurdon JB, Partington GA, De Robertis EM. Injected nuclei in frog oocytes:RNA synthesis and protein exchange. Journal of Embryology and Experimental Morphology. 36: 541-53. PMID 1010978  0.444
1976 Gurdon JB, De Robertis EM, Partington G. Injected nuclei in frog oocytes provide a living cell system for the study of transcriptional control. Nature. 260: 116-20. PMID 943701 DOI: 10.1038/260116A0  0.474
Low-probability matches (unlikely to be authored by this person)
2000 Yamamoto A, Kemp C, Bachiller D, Geissert D, De Robertis EM. Mouse paraxial protocadherin is expressed in trunk mesoderm and is not essential for mouse development. Genesis (New York, N.Y. : 2000). 27: 49-57. PMID 10890978 DOI: 10.1002/1526-968X(200006)27:2<49::AID-GENE10>3.0.CO;2-7  0.297
2001 De Robertis EM, Bouwmeester T. New twists on embryonic patterning. EMBO workshop: embryonic organizer signaling: the next frontiers. Embo Reports. 2: 661-5. PMID 11493592 DOI: 10.1093/embo-reports/kve163  0.297
2016 Demagny H, De Robertis EM. Smad4/DPC4: A barrier against tumor progression driven by RTK/Ras/Erk and Wnt/GSK3 signaling. Molecular & Cellular Oncology. 3: e989133. PMID 27308623 DOI: 10.4161/23723556.2014.989133  0.297
1988 Fritz A, De Robertis EM. Xenopus homeobox-containing cDNAs expressed in early development. Nucleic Acids Research. 16: 1453-69. PMID 2894634 DOI: 10.1093/nar/16.4.1453  0.295
1990 Livingston BD, De Robertis EM, Paulson JC. Expression of beta-galactoside alpha 2,6 sialyltransferase blocks synthesis of polysialic acid in Xenopus embryos. Glycobiology. 1: 39-44. PMID 2136379 DOI: 10.1093/Glycob/1.1.39  0.294
2019 Albrecht LV, Bui MH, De Robertis EM. Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30679275 DOI: 10.1073/pnas.1820161116  0.292
1991 Niehrs C, De Robertis EM. Ectopic expression of a homeobox gene changes cell fate in Xenopus embryos in a position-specific manner. The Embo Journal. 10: 3621-9. PMID 1682146  0.292
1995 Yamada G, Mansouri A, Torres M, Stuart ET, Blum M, Schultz M, De Robertis EM, Gruss P. Targeted mutation of the murine goosecoid gene results in craniofacial defects and neonatal death. Development (Cambridge, England). 121: 2917-22. PMID 7555718  0.289
1988 Oliver G, Wright CV, Hardwicke J, De Robertis EM. A gradient of homeodomain protein in developing forelimbs of Xenopus and mouse embryos. Cell. 55: 1017-24. PMID 2904837 DOI: 10.1016/0092-8674(88)90246-2  0.288
2002 Wessely O, De Robertis EM. Neural plate patterning by secreted signals. Neuron. 33: 489-91. PMID 11856521 DOI: 10.1016/S0896-6273(02)00596-2  0.287
1999 Agius PE, Piccolo S, De Robertis EM. [The head inducer Cerberus in a multivalent extracellular inhibitor]. Journal De La Sociã©Tã© De Biologie. 193: 347-54. PMID 10689616  0.283
2004 Unterseher F, Hefele JA, Giehl K, De Robertis EM, Wedlich D, Schambony A. Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK. The Embo Journal. 23: 3259-69. PMID 15297873 DOI: 10.1038/sj.emboj.7600332  0.281
1991 Cho KW, Morita EA, Wright CV, De Robertis EM. Overexpression of a homeodomain protein confers axis-forming activity to uncommitted Xenopus embryonic cells. Cell. 65: 55-64. PMID 1672833 DOI: 10.1016/0092-8674(91)90407-P  0.281
1992 Leroy P, De Robertis EM. Effects of lithium chloride and retinoic acid on the expression of genes from the Xenopus laevis Hox 2 complex. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 194: 21-32. PMID 1384809 DOI: 10.1002/aja.1001940104  0.28
2010 Zakin L, De Robertis EM. Extracellular regulation of BMP signaling. Current Biology : Cb. 20: R89-92. PMID 20144774 DOI: 10.1016/j.cub.2009.11.021  0.276
1989 Wright CV, Cho KW, Hardwicke J, Collins RH, De Robertis EM. Interference with function of a homeobox gene in Xenopus embryos produces malformations of the anterior spinal cord. Cell. 59: 81-93. PMID 2477158 DOI: 10.1016/0092-8674(89)90871-4  0.274
2000 Wessely O, De Robertis EM. The Xenopus homologue of Bicaudal-C is a localized maternal mRNA that can induce endoderm formation. Development (Cambridge, England). 127: 2053-62. PMID 10769230  0.274
2000 Larraín J, Bachiller D, Lu B, Agius E, Piccolo S, De Robertis EM. BMP-binding modules in chordin: a model for signalling regulation in the extracellular space. Development (Cambridge, England). 127: 821-30. PMID 10648240  0.273
2001 Brizuela BJ, Wessely O, De Robertis EM. Overexpression of the Xenopus tight-junction protein claudin causes randomization of the left-right body axis. Developmental Biology. 230: 217-29. PMID 11161574 DOI: 10.1006/dbio.2000.0116  0.27
2000 Kim SH, Jen WC, De Robertis EM, Kintner C. The protocadherin PAPC establishes segmental boundaries during somitogenesis in xenopus embryos. Current Biology : Cb. 10: 821-30. PMID 10899001 DOI: 10.1016/S0960-9822(00)00580-7  0.269
1990 Jegalian BG, De Robertis EM. The Xenopus laevis Hox 2.1 homeodomain protein is expressed in a narrow band of the hindbrain. The International Journal of Developmental Biology. 34: 453-6. PMID 1981142  0.269
2023 Tejeda-Munoz N, Azbazdar Y, Monka J, Binder G, Dayrit A, Ayala R, O'Brien N, De Robertis EM. The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis. Elife. 12. PMID 37902809 DOI: 10.7554/eLife.89141  0.265
1993 Gaunt SJ, Blum M, De Robertis EM. Expression of the mouse goosecoid gene during mid-embryogenesis may mark mesenchymal cell lineages in the developing head, limbs and body wall. Development (Cambridge, England). 117: 769-78. PMID 8101169  0.262
1993 Gont LK, Steinbeisser H, Blumberg B, de Robertis EM. Tail formation as a continuation of gastrulation: the multiple cell populations of the Xenopus tailbud derive from the late blastopore lip. Development (Cambridge, England). 119: 991-1004. PMID 7916680  0.26
2007 Hurtado C, De Robertis EM. Neural induction in the absence of organizer in salamanders is mediated by MAPK. Developmental Biology. 307: 282-9. PMID 17540356 DOI: 10.1016/j.ydbio.2007.04.049  0.259
2007 Plouhinec JL, De Robertis EM. Systems biology of embryonic morphogens. Molecular Biosystems. 3: 454-7. PMID 17579769 DOI: 10.1039/b701571b  0.253
2015 Ploper D, De Robertis EM. The MITF family of transcription factors: Role in endolysosomal biogenesis, Wnt signaling, and oncogenesis Pharmacological Research. 99: 36-43. DOI: 10.1016/j.phrs.2015.04.006  0.253
2011 Plouhinec JL, Zakin L, De Robertis EM. Systems control of BMP morphogen flow in vertebrate embryos. Current Opinion in Genetics & Development. 21: 696-703. PMID 21937218 DOI: 10.1016/j.gde.2011.09.001  0.251
1993 Jones FS, Holst BD, Minowa O, De Robertis EM, Edelman GM. Binding and transcriptional activation of the promoter for the neural cell adhesion molecule by HoxC6 (Hox-3.3). Proceedings of the National Academy of Sciences of the United States of America. 90: 6557-61. PMID 8393570 DOI: 10.1073/Pnas.90.14.6557  0.25
2016 Demagny H, De Robertis EM. Point mutations in the tumor suppressor Smad4/DPC4 enhance its phosphorylation by GSK3 and reversibly inactivate TGF-β signaling. Molecular & Cellular Oncology. 3: e1025181. PMID 27308538 DOI: 10.1080/23723556.2015.1025181  0.249
1990 Chuong CM, Oliver G, Ting SA, Jegalian BG, Chen HM, De Robertis EM. Gradients of homeoproteins in developing feather buds. Development (Cambridge, England). 110: 1021-30. PMID 2100252  0.249
1987 Wright CV, Cho KW, Fritz A, Bürglin TR, De Robertis EM. A Xenopus laevis gene encodes both homeobox-containing and homeobox-less transcripts. The Embo Journal. 6: 4083-94. PMID 2894983  0.248
1993 Izpisúa-Belmonte JC, De Robertis EM, Storey KG, Stern CD. The homeobox gene goosecoid and the origin of organizer cells in the early chick blastoderm. Cell. 74: 645-59. PMID 7916659 DOI: 10.1016/0092-8674(93)90512-O  0.244
1989 De Robertis EM, Oliver G, Wright CV. Determination of axial polarity in the vertebrate embryo: homeodomain proteins and homeogenetic induction. Cell. 57: 189-91. PMID 2564812 DOI: 10.1016/0092-8674(89)90954-9  0.241
1992 Jones FS, Prediger EA, Bittner DA, De Robertis EM, Edelman GM. Cell adhesion molecules as targets for Hox genes: neural cell adhesion molecule promoter activity is modulated by cotransfection with Hox-2.5 and -2.4. Proceedings of the National Academy of Sciences of the United States of America. 89: 2086-90. PMID 1347944 DOI: 10.1073/Pnas.89.6.2086  0.239
2018 Moriyama Y, De Robertis EM. Embryonic regeneration by relocalization of the Spemann organizer during twinning in . Proceedings of the National Academy of Sciences of the United States of America. PMID 29686106 DOI: 10.1073/pnas.1802749115  0.233
1990 Cho KW, De Robertis EM. Differential activation of Xenopus homeo box genes by mesoderm-inducing growth factors and retinoic acid. Genes & Development. 4: 1910-6. PMID 1980476  0.231
1990 Oliver G, De Robertis EM, Wolpert L, Tickle C. Expression of a homeobox gene in the chick wing bud following application of retinoic acid and grafts of polarizing region tissue. The Embo Journal. 9: 3093-9. PMID 1976508  0.225
1992 Jegalian BG, De Robertis EM. Homeotic transformations in the mouse induced by overexpression of a human Hox3.3 transgene. Cell. 71: 901-10. PMID 1360874 DOI: 10.1016/0092-8674(92)90387-R  0.223
2016 De Robertis EM, Moriyama Y. The Chordin Morphogenetic Pathway. Current Topics in Developmental Biology. 116: 231-45. PMID 26970622 DOI: 10.1016/bs.ctdb.2015.10.003  0.222
2015 De Robertis EM, Moriyama Y. The Chordin Morphogenetic Pathway Current Topics in Developmental Biology. DOI: 10.1016/bs.ctdb.2015.10.003  0.222
1994 De Robertis EM, Fainsod A, Gont LK, Steinbeisser H. The evolution of vertebrate gastrulation. Development (Cambridge, England). Supplement. 117-24. PMID 7579512  0.221
1992 Storey KG, Crossley JM, De Robertis EM, Norris WE, Stern CD. Neural induction and regionalisation in the chick embryo. Development (Cambridge, England). 114: 729-41. PMID 1618139  0.217
2022 De Robertis EM, Tejeda-Muñoz N. Evo-Devo of Urbilateria and its larval forms. Developmental Biology. 487: 10-20. PMID 35443190 DOI: 10.1016/j.ydbio.2022.04.003  0.216
2023 Sosa E, De Robertis EM. The developmental gene Chordin is amplified and expressed in human cancers. Molecular & Cellular Oncology. 10: 2218147. PMID 37260544 DOI: 10.1080/23723556.2023.2218147  0.215
2003 Larraín J, Brown C, De Robertis EM. Integrin-alpha3 mediates binding of Chordin to the cell surface and promotes its endocytosis. Embo Reports. 4: 813-8. PMID 12897802 DOI: 10.1038/sj.embor.embor902  0.215
1997 De Robertis EM, Kim S, Leyns L, Piccolo S, Bachiller D, Agius E, Belo JA, Yamamoto A, Hainski-Brousseau A, Brizuela B, Wessely O, Lu B, Bouwmeester T. Patterning by genes expressed in Spemann's organizer. Cold Spring Harbor Symposia On Quantitative Biology. 62: 169-75. PMID 9598349  0.205
1990 Wright CV, Morita EA, Wilkin DJ, De Robertis EM. The Xenopus XIHbox 6 homeo protein, a marker of posterior neural induction, is expressed in proliferating neurons. Development (Cambridge, England). 109: 225-34. PMID 1976504  0.204
1995 Holley SA, Jackson PD, Sasal Y, Lu B, De Robertis EM, Hoffmann FM, Ferguson EL. A conserved system for dorsal - ventral patterning in insects and vertebrates involving sog and chordin Nature. 376: XII-253.  0.204
1994 Pfeffer PL, De Robertis EM. Regional specificity of RAR gamma isoforms in Xenopus development. Mechanisms of Development. 45: 147-53. PMID 8199051 DOI: 10.1016/0925-4773(94)90028-0  0.204
1999 Zhu L, Belo JA, De Robertis EM, Stern CD. Goosecoid regulates the neural inducing strength of the mouse node. Developmental Biology. 216: 276-81. PMID 10588878 DOI: 10.1006/Dbio.1999.9508  0.202
2007 Yasuda S, Tanaka H, Sugiura H, Okamura K, Sakaguchi T, Tran U, Takemiya T, Mizoguchi A, Yagita Y, Sakurai T, De Robertis EM, Yamagata K. Activity-induced protocadherin arcadlin regulates dendritic spine number by triggering N-cadherin endocytosis via TAO2beta and p38 MAP kinases. Neuron. 56: 456-71. PMID 17988630 DOI: 10.1016/J.Neuron.2007.08.020  0.198
1991 De Robertis EM, Morita EA, Cho KW. Gradient fields and homeobox genes. Development (Cambridge, England). 112: 669-78. PMID 1682124  0.197
1976 Wyllie AH, De Robertis EM. High tyrosinase activity in albino Xenopus laevis oocytes. Journal of Embryology and Experimental Morphology. 36: 555-9. PMID 827598  0.188
1979 De Robertis EM, Olson MV. Transcription and processing of cloned yeast tyrosine tRNA genes microinjected into frog oocytes. Nature. 278: 137-43. PMID 368655 DOI: 10.1038/278137A0  0.187
1989 Fritz AF, Cho KW, Wright CV, Jegalian BG, De Robertis EM. Duplicated homeobox genes in Xenopus. Developmental Biology. 131: 584-8. PMID 2563247 DOI: 10.1016/S0012-1606(89)80029-6  0.187
1984 Zeller R, Carri MT, Mattaj IW, De Robertis EM. Xenopus laevis U1 snRNA genes: characterisation of transcriptionally active genes reveals major and minor repeated gene families. The Embo Journal. 3: 1075-81. PMID 6203742  0.185
1979 De Robertis EM. Probing the program of gene expression utilized in early development. Archivos De Biologã­a Y Medicina Experimentales. 12: 325-9. PMID 95388  0.184
2013 De Robertis EM, Colozza G. Development: scaling to size by protease inhibition. Current Biology : Cb. 23: R652-4. PMID 23928082 DOI: 10.1016/j.cub.2013.06.055  0.183
2022 Tejeda-Muñoz N, Monka J, De Robertis EM. Protocol for culturing and imaging of ectodermal cells from Xenopus. Star Protocols. 3: 101455. PMID 35839770 DOI: 10.1016/j.xpro.2022.101455  0.181
2000 Bachiller D, Klingensmith J, Kemp C, Belo JA, Anderson RM, May SR, McMahon JA, McMahon AP, Harland RM, Rossant J, De Robertis EM. The organizer factors Chordin and Noggin are required for mouse forebrain development. Nature. 403: 658-61. PMID 10688202 DOI: 10.1038/35001072  0.18
1982 Nishikura K, Kurjan J, Hall BD, De Robertis EM. Genetic analysis of the processing of a spliced tRNA. The Embo Journal. 1: 263-8. PMID 6926726  0.178
1973 Ezcurra P, De Robertis EM, Judewicz N, Torres H. Interconvertible forms of bacterial RNA polymerase. Basic Life Sciences. 1: 53-62. PMID 4204122 DOI: 10.1007/978-1-4684-0877-5_5  0.174
1984 Fritz A, Parisot R, Newmeyer D, De Robertis EM. Small nuclear U-ribonucleoproteins in Xenopus laevis development. Uncoupled accumulation of the protein and RNA components. Journal of Molecular Biology. 178: 273-85. PMID 6208365 DOI: 10.1016/0022-2836(84)90144-X  0.17
1999 De Robertis EM. A nose for the embryo: the work of Pieter Nieuwkoop. The International Journal of Developmental Biology. 43: 603-4. PMID 10668969  0.168
1979 de Robertis EM, Black P. Hybrids of Xenopus laevis and Xenopus borealis express proteins from both parents. Developmental Biology. 68: 334-9. PMID 437325  0.167
1996 Catala M, Teillet MA, De Robertis EM, Le Douarin ML. A spinal cord fate map in the avian embryo: while regressing, Hensen's node lays down the notochord and floor plate thus joining the spinal cord lateral walls. Development (Cambridge, England). 122: 2599-610. PMID 8787735  0.164
1986 Newmeyer DD, Lucocq JM, Bürglin TR, De Robertis EM. Assembly in vitro of nuclei active in nuclear protein transport: ATP is required for nucleoplasmin accumulation. The Embo Journal. 5: 501-10. PMID 3709518  0.152
1988 Fritz AF, Martin G, Wright CV, De Robertis EM. Site-specific inversions in repeated Xenopus laevis homeobox gene 2 sequences. Nucleic Acids Research. 16: 9058. PMID 2902559 DOI: 10.1093/nar/16.18.9058  0.148
1996 De Robertis EM, Piccolo S, Lu B, Kim S, Bouwmeester T, Sasai Y. A target gene for organizer homeobox genes Faseb Journal. 10: A1420.  0.147
1981 De Robertis EM, Black P, Nishikura K. Intranuclear location of the tRNA splicing enzymes. Cell. 23: 89-93. PMID 7214528 DOI: 10.1016/0092-8674(81)90273-7  0.146
1983 Bartnik E, de Robertis EM. Mitochondrial transfer RNA genes from fungi (Aspergillus nidulans) and plants (Lupinus luteus) are transcribed in Xenopus laevis oocyte nuclei. Journal of Molecular Biology. 168: 439-44. PMID 6350603 DOI: 10.1016/S0022-2836(83)80027-8  0.145
1995 De Robertis EM. Developmental biology. Dismantling the organizer. Nature. 374: 407-8. PMID 7700346 DOI: 10.1038/374407a0  0.131
2008 De Robertis EM. Evo-devo: variations on ancestral themes. Cell. 132: 185-95. PMID 18243095 DOI: 10.1016/j.cell.2008.01.003  0.129
1968 Narbaitz R, De Robertis EM. Postnatal evolution of steroidogenic cells in the chick ovary. Histochemie. Histochemistry. Histochimie. 15: 187-93. PMID 4246253 DOI: 10.1007/BF00305882  0.127
1985 Mattaj IW, Zeller R, Carrasco AE, Jamrich M, Lienhard S, De Robertis EM. U snRNA gene families in Xenopus laevis. Oxford Surveys On Eukaryotic Genes. 2: 121-40. PMID 3916925  0.127
1990 De Robertis EM, Oliver G, Wright CV. Homeobox genes and the vertebrate body plan. Scientific American. 263: 46-52. PMID 1973846  0.127
1988 De Robertis EM, Burglin TR, Fritz A, Oliver G, Cho K, Wright CV. Sequence conservations in vertebrate homeo-box mRNAs. Archivos De Biologã­a Y Medicina Experimentales. 21: 443-7. PMID 2908262  0.121
2014 De Robertis EM. Yoshiki Sasai 1962-2014. Cell. 158: 1233-5. PMID 25349875  0.12
2014 De Robertis EM. Yoshiki Sasai 1962–2014. Developmental Cell. 30: 509-11. PMID 25340213  0.12
1976 De Robertis EM, Judewicz ND, Torres HN. Regulation of uracil uptake in Escherichia coli by adenosine 3',5'-monophosphate. Biochimica Et Biophysica Acta. 426: 451-63. PMID 178363 DOI: 10.1016/0005-2736(76)90390-4  0.114
1983 De Robertis EM. Nucleocytoplasmic segregation of proteins and RNAs. Cell. 32: 1021-5. PMID 6188533 DOI: 10.1016/0092-8674(83)90285-4  0.112
1970 Narbaitz R, De Robertis EM. Steroid-producing cells in chick intersexual gonads. General and Comparative Endocrinology. 14: 164-9. PMID 5461621 DOI: 10.1016/0016-6480(70)90020-1  0.111
1987 Mattaj IW, Coppard NJ, Brown RS, Clark BF, De Robertis EM. 42S p48--the most abundant protein in previtellogenic Xenopus oocytes--resembles elongation factor 1 alpha structurally and functionally. The Embo Journal. 6: 2409-13. PMID 2444435  0.103
2014 De Robertis EM. Lessons from a great developmental biologist. Differentiation; Research in Biological Diversity. 88: 3-8. PMID 25455202 DOI: 10.1016/j.diff.2013.12.004  0.1
1982 Matter L, Schopfer K, Wilhelm JA, Nyffenegger T, Parisot RF, De Robertis EM. Molecular characterization of ribonucleoprotein antigens bound by antinuclear antibodies. A diagnostic evaluation. Arthritis and Rheumatism. 25: 1278-83. PMID 6753854 DOI: 10.1002/art.1780251102  0.094
1982 De Robertis EM, Lienhard S, Parisot RF. Intracellular transport of microinjected 5S and small nuclear RNAs. Nature. 295: 572-7. PMID 6173771 DOI: 10.1038/295572a0  0.093
1987 Bürglin TR, Wright CV, De Robertis EM. Translational control in homoeobox mRNAs? Nature. 330: 701-2. PMID 2892138 DOI: 10.1038/330701c0  0.08
1993 De Robertis EM, Blum M, Niehrs C, Steinbeisser H. Goosecoid and the organizer Journal of Neuroscience. 13: 167-171.  0.076
1972 Barrantes FJ, La Torre JL, Llorente de Carlin MC, De Robertis E. Studies on proteolipid proteins from cerebral cortex. I. Preparation and some properties. Biochimica Et Biophysica Acta. 263: 368-81. PMID 4337943 DOI: 10.1016/0005-2795(72)90089-X  0.071
1973 Judewicz ND, De Robertis EM, Torres HN. Inhibition of Escherichia coli growth by cyclic adenosine 3', 5'-monophosphate. Biochemical and Biophysical Research Communications. 52: 1257-62. PMID 4352239  0.071
1973 De Robertis EM, Judewicz RD, Torres HN. On the control mechanism of bacterial growth by cyclic adenosine 3',5'-monophosphate. Biochemical and Biophysical Research Communications. 55: 758-64. PMID 4357431 DOI: 10.1016/0006-291X(73)91209-6  0.069
1981 Nishikura K, De Robertis EM. RNA processing in microinjected Xenopus oocytes. Sequential addition of base modifications in the spliced transfer RNA. Journal of Molecular Biology. 145: 405-20. PMID 7196457 DOI: 10.1016/0022-2836(81)90212-6  0.069
2022 De Robertis EM. The impact of developmental biology in the last 100 years. Developmental Biology. 489: 118-121. PMID 35716718 DOI: 10.1016/j.ydbio.2022.06.007  0.061
1972 De Robertis EM, Ezcurra PM, Judewicz ND, Pucci PR, Torres HN. Inhibition of E. coli RNA polymerase by polyadenylic acid. Febs Letters. 25: 175-178. PMID 11946746  0.056
1997 De Robertis EM. Evolving protostomes and deuterostomes Nature. 387: 25.  0.052
1976 Saraceno H, De Robertis E. Isolation by affinity chromatography of a cholinergic proteolipid from Nucleus caudatus. Biochemical and Biophysical Research Communications. 69: 555-61. PMID 1267802 DOI: 10.1016/0006-291X(76)90556-8  0.052
1997 De Robertis EM. Evolutionary biology. The ancestry of segmentation. Nature. 387: 25-6. PMID 9139817 DOI: 10.1038/387025a0  0.044
2008 De Robertis EM. The molecular ancestry of segmentation mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 105: 16411-2. PMID 18948592 DOI: 10.1073/pnas.0808774105  0.043
2023 Ringborg U, von Braun J, Celis J, Baumann M, Berns A, Eggermont A, Heard E, Heitor M, Chandy M, Chen CJ, Costa A, De Lorenzo F, De Robertis EM, Dubee FC, Ernberg I, et al. Strategies to decrease inequalities in cancer therapeutics, care and prevention. Molecular Oncology. PMID 38135904 DOI: 10.1002/1878-0261.13575  0.03
1974 Judewicz ND, De Robertis EM, Torres HN. Control of uracil transport by cyclic AMP in E. coli. Febs Letters. 45: 155-8. PMID 4369888 DOI: 10.1016/0014-5793(74)80834-3  0.03
2008 De Robertis EM. Eddy M. De Robertis. Current Biology : Cb. 18: R318-20. PMID 18561377 DOI: 10.1016/j.cub.2008.02.037  0.01
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