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Joel D. Boerckel, Ph.D. - Publications

Affiliations: 
2011 Georgia Institute of Technology, Atlanta, GA 
Area:
Biomedical Engineering, Mechanical Engineering, Biomechanics Biophysics
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Collins JM, Lang A, Parisi C, Moharrer Y, Nijsure MP, Thomas Kim JH, Ahmed S, Szeto GL, Qin L, Gottardi R, Dyment NA, Nowlan NC, Boerckel JD. YAP and TAZ couple osteoblast precursor mobilization to angiogenesis and mechanoregulation in murine bone development. Developmental Cell. PMID 38141609 DOI: 10.1016/j.devcel.2023.11.029  0.415
2023 Yao L, Lu J, Zhong L, Wei Y, Gui T, Wang L, Ahn J, Boerckel JD, Rux D, Mundy C, Qin L, Pacifici M. Activin A marks a novel progenitor cell population during fracture healing and reveals a therapeutic strategy. Elife. 12. PMID 38079220 DOI: 10.7554/eLife.89822  0.377
2023 Lang A, Benn A, Wolter A, Balcaen T, Collins J, Kerckhofs G, Zwijsen A, Boerckel JD. Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis during long bone growth. Biorxiv : the Preprint Server For Biology. PMID 36712097 DOI: 10.1101/2023.01.07.522994  0.38
2023 Collins JM, Lang A, Parisi C, Moharrer Y, Nijsure MP, Kim JHT, Szeto GL, Qin L, Gottardi RL, Dyment NA, Nowlan NC, Boerckel JD. YAP and TAZ couple osteoblast precursor mobilization to angiogenesis and mechanoregulated bone development. Biorxiv : the Preprint Server For Biology. PMID 36711590 DOI: 10.1101/2023.01.20.524918  0.403
2021 Moharrer Y, Boerckel JD. Tunnels in the rock: Dynamics of osteocyte morphogenesis. Bone. 153: 116104. PMID 34245936 DOI: 10.1016/j.bone.2021.116104  0.353
2021 Moharrer Y, Boerckel JD. Tunnels in the rock: Dynamics of osteocyte morphogenesis. Bone. 153: 116104. PMID 34245936 DOI: 10.1016/j.bone.2021.116104  0.353
2021 McDermott AM, Eastburn EA, Kelly DJ, Boerckel JD. Effects of chondrogenic priming duration on mechanoregulation of engineered cartilage. Journal of Biomechanics. 125: 110580. PMID 34198021 DOI: 10.1016/j.jbiomech.2021.110580  0.342
2021 Herberg S, Varghai D, Alt DS, Dang PN, Park H, Cheng Y, Shin JY, Dikina AD, Boerckel JD, Rolle MW, Alsberg E. Scaffold-free human mesenchymal stem cell construct geometry regulates long bone regeneration. Communications Biology. 4: 89. PMID 33469154 DOI: 10.1038/s42003-020-01576-y  0.555
2020 Ruehle MA, Eastburn EA, LaBelle SA, Krishnan L, Weiss JA, Boerckel JD, Wood LB, Guldberg RE, Willett NJ. Extracellular matrix compression temporally regulates microvascular angiogenesis. Science Advances. 6. PMID 32937368 DOI: 10.1126/Sciadv.Abb6351  0.489
2020 Kegelman CD, Nijsure MP, Moharrer Y, Pearson HB, Dawahare JH, Jordan KM, Qin L, Boerckel JD. YAP and TAZ promote periosteal osteoblast precursor expansion and differentiation for fracture repair. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 32835424 DOI: 10.1002/Jbmr.4166  0.481
2019 Kegelman CD, Coulombe JC, Jordan KM, Horan DJ, Qin L, Robling AG, Ferguson VL, Bellido TM, Boerckel JD. YAP and TAZ Mediate Osteocyte Perilacunar/Canalicular Remodeling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31610061 DOI: 10.1002/Jbmr.3876  0.539
2019 Herberg S, McDermott AM, Dang PN, Alt DS, Tang R, Dawahare JH, Varghai D, Shin JY, McMillan A, Dikina AD, He F, Lee YB, Cheng Y, Umemori K, Wong PC, ... ... Boerckel JD, et al. Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair. Science Advances. 5: eaax2476. PMID 31489377 DOI: 10.1126/Sciadv.Aax2476  0.561
2019 McDermott AM, Herberg S, Mason DE, Collins JM, Pearson HB, Dawahare JH, Tang R, Patwa AN, Grinstaff MW, Kelly DJ, Alsberg E, Boerckel JD. Recapitulating bone development through engineered mesenchymal condensations and mechanical cues for tissue regeneration. Science Translational Medicine. 11. PMID 31167930 DOI: 10.1126/Scitranslmed.Aav7756  0.646
2019 Pearson HB, Mason DE, Kegelman CD, Zhao L, Dawahare JH, Kacena MA, Boerckel JD. Effects of BMP-2 on neovascularization during large bone defect regeneration. Tissue Engineering. Part A. PMID 30973074 DOI: 10.1089/Ten.Tea.2018.0326  0.568
2019 Mason DE, Collins JM, Dawahare JH, Nguyen TD, Lin Y, Voytik-Harbin SL, Zorlutuna P, Yoder MC, Boerckel JD. YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility. The Journal of Cell Biology. PMID 30737263 DOI: 10.1083/Jcb.201806065  0.305
2019 Wang L, Tower RJ, Chandra A, Yao L, Tong W, Xiong Z, Tang K, Zhang Y, Liu XS, Boerckel JD, Guo X, Ahn J, Qin L. Periosteal Mesenchymal Progenitor Dysfunction and Extraskeletally-Derived Fibrosis Contribute to Atrophic Fracture Nonunion. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 30602062 DOI: 10.1002/Jbmr.3626  0.447
2018 Kegelman CD, Mason DE, Dawahare JH, Horan DJ, Vigil GD, Howard SS, Robling AG, Bellido TM, Boerckel JD. Skeletal cell YAP and TAZ combinatorially promote bone development. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201700872R. PMID 29401582 DOI: 10.1096/Fj.201700872R  0.523
2017 Curtis KJ, Coughlin TR, Mason DE, Boerckel JD, Niebur GL. Bone marrow mechanotransduction in porcine explants alters kinase activation and enhances trabecular bone formation in the absence of osteocyte signaling. Bone. 107: 78-87. PMID 29154967 DOI: 10.1016/J.Bone.2017.11.007  0.545
2017 Marcucio RS, Qin L, Alsberg E, Boerckel JD. Reverse engineering development: crosstalk opportunities between developmental biology and tissue engineering. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 28660712 DOI: 10.1002/Jor.23636  0.419
2016 Coughlin T, Moreno RR, Mason D, Nystrom L, Boerckel J, Niebur G, Littlepage LE. Bone: A Fertile Soil for Cancer Metastasis. Current Drug Targets. PMID 28025941 DOI: 10.2174/1389450117666161226121650  0.528
2016 McDermott AM, Mason DE, Lin AS, Guldberg RE, Boerckel JD. Influence of structural load-bearing scaffolds on mechanical load- and BMP-2-mediated bone regeneration. Journal of the Mechanical Behavior of Biomedical Materials. 62: 169-181. PMID 27208510 DOI: 10.1016/J.Jmbbm.2016.05.010  0.723
2016 Meagher MJ, Weiss-Bilka HE, Best ME, Boerckel JD, Wagner DR, Roeder RK. Acellular Hydroxyapatite-Collagen Scaffolds Support Angiogenesis and Osteogenic Gene Expression in an Ectopic Murine Model: Effects of Hydroxyapatite Volume Fraction. Journal of Biomedical Materials Research. Part A. PMID 27112109 DOI: 10.1002/Jbm.A.35760  0.433
2016 Xie Y, Rustom LE, McDermott AM, Boerckel JD, Johnson AJ, Alleyne AG, Hoelzle DJ. Net shape fabrication of calcium phosphate scaffolds with multiple material domains. Biofabrication. 8: 015005. PMID 26744897 DOI: 10.1088/1758-5090/8/1/015005  0.375
2015 Griffin KS, Davis KM, McKinley TO, Anglen JO, Chu TMG, Boerckel JD, Kacena MA. Evolution of Bone Grafting: Bone Grafts and Tissue Engineering Strategies for Vascularized Bone Regeneration Clinical Reviews in Bone and Mineral Metabolism. DOI: 10.1007/S12018-015-9194-9  0.615
2014 Boerckel JD, Mason DE, McDermott AM, Alsberg E. Microcomputed tomography: approaches and applications in bioengineering. Stem Cell Research & Therapy. 5: 144. PMID 25689288 DOI: 10.1186/Scrt534  0.442
2014 Uhrig BA, Clements IP, Boerckel JD, Huebsch N, Bellamkonda RV, Guldberg RE. Characterization of a composite injury model of severe lower limb bone and nerve trauma. Journal of Tissue Engineering and Regenerative Medicine. 8: 432-41. PMID 22689452 DOI: 10.1002/Term.1537  0.647
2013 Uhrig BA, Boerckel JD, Willett NJ, Li MT, Huebsch N, Guldberg RE. Recovery from hind limb ischemia enhances rhBMP-2-mediated segmental bone defect repair in a rat composite injury model. Bone. 55: 410-7. PMID 23664918 DOI: 10.1016/J.Bone.2013.04.027  0.684
2013 Willett NJ, Li MT, Uhrig BA, Boerckel JD, Huebsch N, Lundgren TL, Warren GL, Guldberg RE. Attenuated human bone morphogenetic protein-2-mediated bone regeneration in a rat model of composite bone and muscle injury. Tissue Engineering. Part C, Methods. 19: 316-25. PMID 22992043 DOI: 10.1089/Ten.Tec.2012.0290  0.648
2012 Diab T, Pritchard EM, Uhrig BA, Boerckel JD, Kaplan DL, Guldberg RE. A silk hydrogel-based delivery system of bone morphogenetic protein for the treatment of large bone defects. Journal of the Mechanical Behavior of Biomedical Materials. 11: 123-31. PMID 22658161 DOI: 10.1016/J.Jmbbm.2011.11.007  0.697
2012 Berner A, Boerckel JD, Saifzadeh S, Steck R, Ren J, Vaquette C, Zhang JQ, Nerlich M, Guldberg RE, Hutmacher DW, Woodruff MA. Biomimetic tubular nanofiber mesh and platelet rich plasma-mediated delivery of BMP-7 for large bone defect regeneration. Cell and Tissue Research. 347: 603-12. PMID 22277992 DOI: 10.1007/S00441-011-1298-Z  0.703
2012 Boerckel JD, Kolambkar YM, Stevens HY, Lin AS, Dupont KM, Guldberg RE. Effects of in vivo mechanical loading on large bone defect regeneration. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 30: 1067-75. PMID 22170172 DOI: 10.1002/Jor.22042  0.681
2012 Dupont KM, Boerckel JD, Stevens HY, Diab T, Kolambkar YM, Takahata M, Schwarz EM, Guldberg RE. Synthetic scaffold coating with adeno-associated virus encoding BMP2 to promote endogenous bone repair. Cell and Tissue Research. 347: 575-88. PMID 21695398 DOI: 10.1007/S00441-011-1197-3  0.692
2011 Boerckel JD, Uhrig BA, Willett NJ, Huebsch N, Guldberg RE. Mechanical regulation of vascular growth and tissue regeneration in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: E674-80. PMID 21876139 DOI: 10.1073/Pnas.1107019108  0.686
2011 Johnson MR, Boerckel JD, Dupont KM, Guldberg RE. Functional restoration of critically sized segmental defects with bone morphogenetic protein-2 and heparin treatment. Clinical Orthopaedics and Related Research. 469: 3111-7. PMID 21863396 DOI: 10.1007/S11999-011-2012-X  0.758
2011 Kolambkar YM, Boerckel JD, Dupont KM, Bajin M, Huebsch N, Mooney DJ, Hutmacher DW, Guldberg RE. Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects. Bone. 49: 485-92. PMID 21621027 DOI: 10.1016/J.Bone.2011.05.010  0.697
2011 Boerckel JD, Kolambkar YM, Dupont KM, Uhrig BA, Phelps EA, Stevens HY, García AJ, Guldberg RE. Effects of protein dose and delivery system on BMP-mediated bone regeneration. Biomaterials. 32: 5241-51. PMID 21507479 DOI: 10.1016/J.Biomaterials.2011.03.063  0.631
2011 Kolambkar YM, Dupont KM, Boerckel JD, Huebsch N, Mooney DJ, Hutmacher DW, Guldberg RE. An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects. Biomaterials. 32: 65-74. PMID 20864165 DOI: 10.1016/J.Biomaterials.2010.08.074  0.722
2011 Boerckel JD, Gemmiti CV, Kolambkar YM, Porter BD, Guldberg RE. Physical Stress as a Factor in Tissue Growth and Remodeling Principles of Regenerative Medicine. 493-515. DOI: 10.1016/B978-0-12-381422-7.10028-8  0.581
2010 Dupont KM, Sharma K, Stevens HY, Boerckel JD, García AJ, Guldberg RE. Human stem cell delivery for treatment of large segmental bone defects. Proceedings of the National Academy of Sciences of the United States of America. 107: 3305-10. PMID 20133731 DOI: 10.1073/Pnas.0905444107  0.639
2010 Kolambkar YM, Boerckel JD, Dupont KM, Bajin M, Huebsch N, Mooney DJ, Bellamkonda RV, Garcia AJ, Hutmacher DW, Guldberg RE. Electrospun nanofibers meshes for the repair of bone defects American Association of Textile Chemists and Colorists International Conference 2010. 357-361.  0.635
2009 Boerckel JD, Dupont KM, Kolambkar YM, Lin AS, Guldberg RE. In vivo model for evaluating the effects of mechanical stimulation on tissue-engineered bone repair. Journal of Biomechanical Engineering. 131: 084502. PMID 19604025 DOI: 10.1115/1.3148472  0.713
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