Lawrence D. Middaugh - Publications

Medical University of South Carolina, Charleston, SC, United States 

127 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Karakostas T, Hsiang S, Boger H, Middaugh L, Granholm AC. Three-dimensional rodent motion analysis and neurodegenerative disorders. Journal of Neuroscience Methods. 231: 31-7. PMID 24129039 DOI: 10.1016/J.Jneumeth.2013.09.009  1
2013 Griffin WC, McGovern RW, Bell GH, Randall PK, Middaugh LD, Patrick KS. Interactive effects of methylphenidate and alcohol on discrimination, conditioned place preference and motor coordination in C57BL/6J mice. Psychopharmacology. 225: 613-25. PMID 22955568 DOI: 10.1007/S00213-012-2849-Z  1
2012 Griffin WC, Nguyen SA, Deleon CP, Middaugh LD. Effects of vigabatrin, an irreversible GABA transaminase inhibitor, on ethanol reinforcement and ethanol discriminative stimuli in mice. Behavioural Pharmacology. 23: 178-90. PMID 22336593 DOI: 10.1097/Fbp.0B013E3283512C56  1
2012 Littrell OM, Pomerleau F, Huettl P, Surgener S, McGinty JF, Middaugh LD, Granholm AC, Gerhardt GA, Boger HA. Enhanced dopamine transporter activity in middle-aged Gdnf heterozygous mice. Neurobiology of Aging. 33: 427.e1-14. PMID 21144620 DOI: 10.1016/J.Neurobiolaging.2010.10.013  1
2011 McGovern RW, Middaugh LD, Patrick KS, Griffin WC. The discriminative stimulus properties of methylphenidate in C57BL/6J mice. Behavioural Pharmacology. 22: 14-22. PMID 21160424 DOI: 10.1097/Fbp.0B013E3283423D92  1
2011 Granholm AC, Zaman V, Godbee J, Smith M, Ramadan R, Umphlet C, Randall P, Bhat NR, Rohrer B, Middaugh LD, Boger HA. Prenatal LPS increases inflammation in the substantia nigra of Gdnf heterozygous mice. Brain Pathology (Zurich, Switzerland). 21: 330-48. PMID 20969653 DOI: 10.1111/J.1750-3639.2010.00457.X  1
2011 Boger HA, Mannangatti P, Samuvel DJ, Saylor AJ, Bender TS, McGinty JF, Fortress AM, Zaman V, Huang P, Middaugh LD, Randall PK, Jayanthi LD, Rohrer B, Helke KL, Granholm AC, et al. Effects of brain-derived neurotrophic factor on dopaminergic function and motor behavior during aging. Genes, Brain, and Behavior. 10: 186-98. PMID 20860702 DOI: 10.1111/J.1601-183X.2010.00654.X  1
2010 Griffin WC, Novak AJ, Middaugh LD, Patrick KS. The interactive effects of methylphenidate and ethanol on ethanol consumption and locomotor activity in mice. Pharmacology, Biochemistry, and Behavior. 95: 267-72. PMID 20122954 DOI: 10.1016/J.Pbb.2010.01.009  1
2010 Boger HA, Granholm AC, McGinty JF, Middaugh LD. A dual-hit animal model for age-related parkinsonism. Progress in Neurobiology. 90: 217-29. PMID 19853012 DOI: 10.1016/J.Pneurobio.2009.10.013  1
2009 Boger HA, Middaugh LD, Granholm AC, McGinty JF. Minocycline restores striatal tyrosine hydroxylase in GDNF heterozygous mice but not in methamphetamine-treated mice. Neurobiology of Disease. 33: 459-66. PMID 19110059 DOI: 10.1016/J.Nbd.2008.11.013  1
2009 Griffin WC, Lopez MF, Yanke AB, Middaugh LD, Becker HC. Repeated cycles of chronic intermittent ethanol exposure in mice increases voluntary ethanol drinking and ethanol concentrations in the nucleus accumbens. Psychopharmacology. 201: 569-80. PMID 18791704 DOI: 10.1007/S00213-008-1324-3  1
2008 Zaman V, Boger HA, Granholm AC, Rohrer B, Moore A, Buhusi M, Gerhardt GA, Hoffer BJ, Middaugh LD. The nigrostriatal dopamine system of aging GFRalpha-1 heterozygous mice: neurochemistry, morphology and behavior. The European Journal of Neuroscience. 28: 1557-68. PMID 18973577 DOI: 10.1111/J.1460-9568.2008.06456.X  1
2008 Boger HA, Middaugh LD, Zaman V, Hoffer B, Granholm AC. Differential effects of the dopamine neurotoxin MPTP in animals with a partial deletion of the GDNF receptor, GFR alpha1, gene. Brain Research. 1241: 18-28. PMID 18822276 DOI: 10.1016/J.Brainres.2008.09.011  1
2007 Boger HA, Middaugh LD, Patrick KS, Ramamoorthy S, Denehy ED, Zhu H, Pacchioni AM, Granholm AC, McGinty JF. Long-term consequences of methamphetamine exposure in young adults are exacerbated in glial cell line-derived neurotrophic factor heterozygous mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8816-25. PMID 17699663 DOI: 10.1523/Jneurosci.1067-07.2007  1
2007 Griffin WC, Randall PK, Middaugh LD. Intravenous cocaine self-administration: individual differences in male and female C57BL/6J mice. Pharmacology, Biochemistry, and Behavior. 87: 267-79. PMID 17561241 DOI: 10.1016/J.Pbb.2007.04.023  1
2007 Cook-Easterwood J, Middaugh LD, Griffin WC, Khan I, Tyor WR. Highly active antiretroviral therapy of cognitive dysfunction and neuronal abnormalities in SCID mice with HIV encephalitis. Experimental Neurology. 205: 506-12. PMID 17442303 DOI: 10.1016/J.Expneurol.2007.03.007  1
2007 Griffin WC, Middaugh LD, Becker HC. Voluntary ethanol drinking in mice and ethanol concentrations in the nucleus accumbens. Brain Research. 1138: 208-13. PMID 17275791 DOI: 10.1016/J.Brainres.2006.12.071  1
2007 Williard RL, Middaugh LD, Zhu HJ, Patrick KS. Methylphenidate and its ethanol transesterification metabolite ethylphenidate: brain disposition, monoamine transporters and motor activity. Behavioural Pharmacology. 18: 39-51. PMID 17218796 DOI: 10.1097/Fbp.0B013E3280143226  1
2007 Griffin WC, Middaugh LD, Tyor WR. Chronic cocaine exposure in the SCID mouse model of HIV encephalitis. Brain Research. 1134: 214-9. PMID 17189621 DOI: 10.1016/J.Brainres.2006.11.059  1
2007 Nguyen SA, Malcolm R, Middaugh LD. Topiramate reduces ethanol consumption by C57BL/6 mice. Synapse (New York, N.Y.). 61: 150-6. PMID 17146766 DOI: 10.1002/Syn.20350  1
2006 Melendez RI, Middaugh LD, Kalivas PW. Development of an alcohol deprivation and escalation effect in C57BL/6J mice. Alcoholism, Clinical and Experimental Research. 30: 2017-25. PMID 17117967 DOI: 10.1111/J.1530-0277.2006.00248.X  1
2006 Boger HA, Middaugh LD, Huang P, Zaman V, Smith AC, Hoffer BJ, Tomac AC, Granholm AC. A partial GDNF depletion leads to earlier age-related deterioration of motor function and tyrosine hydroxylase expression in the substantia nigra. Experimental Neurology. 202: 336-47. PMID 16889771 DOI: 10.1016/J.Expneurol.2006.06.006  1
2006 Lominac KD, Kapasova Z, Hannun RA, Patterson C, Middaugh LD, Szumlinski KK. Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: potential insight into their anti-addictive properties. Drug and Alcohol Dependence. 85: 142-56. PMID 16697125 DOI: 10.1016/J.Drugalcdep.2006.04.003  1
2006 Zhu HJ, Wang JS, DeVane CL, Williard RL, Donovan JL, Middaugh LD, Gibson BB, Patrick KS, Markowitz JS. The role of the polymorphic efflux transporter P-glycoprotein on the brain accumulation of d-methylphenidate and d-amphetamine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1116-21. PMID 16621932 DOI: 10.1124/Dmd.106.009605  1
2006 Wiren KM, Hashimoto JG, Alele PE, Devaud LL, Price KL, Middaugh LD, Grant KA, Finn DA. Impact of sex: determination of alcohol neuroadaptation and reinforcement. Alcoholism, Clinical and Experimental Research. 30: 233-42. PMID 16441272 DOI: 10.1111/J.1530-0277.2006.00032.X  1
2006 Griffin WC, Boger HA, Granholm AC, Middaugh LD. Partial deletion of glial cell line-derived neurotrophic factor (GDNF) in mice: Effects on sucrose reward and striatal GDNF concentrations. Brain Research. 1068: 257-60. PMID 16364262 DOI: 10.1016/J.Brainres.2005.10.080  1
2006 Griffin WC, Middaugh LD. The influence of sex on extracellular dopamine and locomotor activity in C57BL/6J mice before and after acute cocaine challenge. Synapse (New York, N.Y.). 59: 74-81. PMID 16270301 DOI: 10.1002/Syn.20218  1
2005 Szumlinski KK, Lominac KD, Oleson EB, Walker JK, Mason A, Dehoff MH, Klugmann M, Klugman M, Cagle S, Welt K, During M, Worley PF, Middaugh LD, Kalivas PW. Homer2 is necessary for EtOH-induced neuroplasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7054-61. PMID 16049182 DOI: 10.1523/Jneurosci.1529-05.2005  1
2005 Szumlinski KK, Lominac KD, Frys KA, Middaugh LD. Genetic variation in heroin-induced changes in behaviour: effects of B6 strain dose on conditioned reward and locomotor sensitization in 129-B6 hybrid mice. Genes, Brain, and Behavior. 4: 324-36. PMID 16011579 DOI: 10.1111/J.1601-183X.2004.00111.X  1
2005 Cook JE, Dasgupta S, Middaugh LD, Terry EC, Gorry PR, Wesselingh SL, Tyor WR. Highly active antiretroviral therapy and human immunodeficiency virus encephalitis. Annals of Neurology. 57: 795-803. PMID 15852478 DOI: 10.1002/Ana.20479  1
2005 Patrick KS, Williard RL, VanWert AL, Dowd JJ, Oatis JE, Middaugh LD. Synthesis and pharmacology of ethylphenidate enantiomers: the human transesterification metabolite of methylphenidate and ethanol. Journal of Medicinal Chemistry. 48: 2876-81. PMID 15828826 DOI: 10.1021/Jm0490989  1
2005 Nguyen SA, Deleon CP, Malcolm RJ, Middaugh LD. Tiagabine reduces ethanol reward in C57BL/6 mice under acute and chronic administration regimens. Synapse (New York, N.Y.). 56: 135-46. PMID 15765538 DOI: 10.1002/Syn.20138  1
2004 Price KL, Middaugh LD. The dopamine D1 antagonist reduces ethanol reward for C57BL/6 mice. Alcoholism, Clinical and Experimental Research. 28: 1666-75. PMID 15547453 DOI: 10.1097/01.Alc.0000145783.39748.E6  1
2004 Szumlinski KK, Dehoff MH, Kang SH, Frys KA, Lominac KD, Klugmann M, Rohrer J, Griffin W, Toda S, Champtiaux NP, Berry T, Tu JC, Shealy SE, During MJ, Middaugh LD, et al. Homer proteins regulate sensitivity to cocaine. Neuron. 43: 401-13. PMID 15294147 DOI: 10.1016/J.Neuron.2004.07.019  1
2004 Griffin WC, Middaugh LD, Cook JE, Tyor WR. The severe combined immunodeficient (SCID) mouse model of human immunodeficiency virus encephalitis: deficits in cognitive function. Journal of Neurovirology. 10: 109-15. PMID 15204929 DOI: 10.1080/13550280490428333  1
2004 Becker HC, Crissman AM, Studders S, Kelley BM, Middaugh LD. Differential neurosensitivity to the discriminative stimulus properties of ethanol in C57BL/6J and C3H/He mice. Alcoholism, Clinical and Experimental Research. 28: 712-9. PMID 15166645 DOI: 10.1097/01.Alc.0000125351.09265.F0  1
2003 Zaman V, Li Z, Middaugh L, Ramamoorthy S, Rohrer B, Nelson ME, Tomac AC, Hoffer BJ, Gerhardt GA, Granholm AC. The Noradrenergic System of Aged GDNF Heterozygous Mice. Cell Transplantation. 12: 291-303. PMID 28853928 DOI: 10.3727/000000003108746740  0.36
2003 Middaugh LD, Szumlinski KK, Van Patten Y, Marlowe AL, Kalivas PW. Chronic ethanol consumption by C57BL/6 mice promotes tolerance to its interoceptive cues and increases extracellular dopamine, an effect blocked by naltrexone. Alcoholism, Clinical and Experimental Research. 27: 1892-900. PMID 14691376 DOI: 10.1097/01.Alc.0000099264.36220.48  1
2003 Szumlinski KK, Toda S, Middaugh LD, Worley PF, Kalivas PW. Evidence for a relationship between Group 1 mGluR hypofunction and increased cocaine and ethanol sensitivity in Homer2 null mutant mice. Annals of the New York Academy of Sciences. 1003: 468-71. PMID 14684491 DOI: 10.1196/Annals.1300.055  1
2003 Griffin WC, Middaugh LD. Acquisition of lever pressing for cocaine in C57BL/6J mice: effects of prior Pavlovian conditioning. Pharmacology, Biochemistry, and Behavior. 76: 543-9. PMID 14643854 DOI: 10.1016/J.Pbb.2003.09.010  1
2003 Middaugh LD, Dow-Edwards D, Li AA, Sandler JD, Seed J, Sheets LP, Shuey DL, Slikker W, Weisenburger WP, Wise LD, Selwyn MR. Neurobehavioral assessment: a survey of use and value in safety assessment studies. Toxicological Sciences : An Official Journal of the Society of Toxicology. 76: 250-61. PMID 12915715 DOI: 10.1093/Toxsci/Kfg211  1
2003 Fuchs RA, See RE, Middaugh LD. Conditioned stimulus-induced reinstatement of extinguished cocaine seeking in C57BL/6 mice: a mouse model of drug relapse. Brain Research. 973: 99-106. PMID 12729958 DOI: 10.1016/S0006-8993(03)02560-5  1
2002 Szumlinski KK, Price KL, Frys KA, Middaugh LD. Unconditioned and conditioned factors contribute to the 'reinstatement' of cocaine place conditioning following extinction in C57BL/6 mice. Behavioural Brain Research. 136: 151-60. PMID 12385800 DOI: 10.1016/S0166-4328(02)00102-X  1
2000 Middaugh LD, Bandy AL. Naltrexone effects on ethanol consumption and response to ethanol conditioned cues in C57BL/6 mice. Psychopharmacology. 151: 321-7. PMID 11026738 DOI: 10.1007/S002130000479  1
2000 Middaugh LD, Lee AM, Bandy AL. Ethanol reinforcement in nondeprived mice: effects of abstinence and naltrexone. Alcoholism, Clinical and Experimental Research. 24: 1172-9. PMID 10968654 DOI: 10.1111/J.1530-0277.2000.Tb02080.X  1
2000 Middaugh LD, Kelley BM, Groseclose CH, Cuison ER. Delta-opioid and 5-HT3 receptor antagonist effects on ethanol reward and discrimination in C57BL/6 mice. Pharmacology, Biochemistry, and Behavior. 65: 145-54. PMID 10638648 DOI: 10.1016/S0091-3057(99)00184-7  1
1999 Kelley BM, Middaugh LD. Periadolescent nicotine exposure reduces cocaine reward in adult mice. Journal of Addictive Diseases. 18: 27-39. PMID 10507580 DOI: 10.1300/J069V18N03_04  1
1999 Nocjar C, Middaugh LD, Tavernetti M. Ethanol consumption and place-preference conditioning in the alcohol-preferring C57BL/6 mouse: relationship with motor activity patterns. Alcoholism, Clinical and Experimental Research. 23: 683-92. PMID 10235304 DOI: 10.1111/J.1530-0277.1999.Tb04170.X  1
1999 Middaugh LD, Kelley BM. Operant ethanol reward in C57BL/6 mice: influence of gender and procedural variables. Alcohol (Fayetteville, N.Y.). 17: 185-94. PMID 10231166 DOI: 10.1016/S0741-8329(98)00056-1  1
1999 Middaugh LD, Kelley BM, Bandy AL, McGroarty KK. Ethanol consumption by C57BL/6 mice: influence of gender and procedural variables. Alcohol (Fayetteville, N.Y.). 17: 175-83. PMID 10231165 DOI: 10.1016/S0741-8329(98)00055-X  1
1999 Tyor WR, Middaugh LD. Do alcohol and cocaine abuse alter the course of HIV-associated dementia complex? Journal of Leukocyte Biology. 65: 475-81. PMID 10204576 DOI: 10.1002/Jlb.65.4.475  1
1999 Middaugh LD, Kelley BM, Cuison ER, Groseclose CH. Naltrexone effects on ethanol reward and discrimination in C57BL/6 mice. Alcoholism, Clinical and Experimental Research. 23: 456-64. PMID 10195818 DOI: 10.1111/J.1530-0277.1999.Tb04137.X  1
1999 Middaugh LD, Kelley BM, Cuison ER, Groseclose CH. Naltrexone Effects on Ethanol Reward and Discrimination in C57BL/6 Mice Alcoholism: Clinical and Experimental Research. 23: 456-464. DOI: 10.1111/j.1530-0277.1999.tb04137.x  0.44
1998 Avgeropoulos N, Kelley B, Middaugh L, Arrigo S, Persidsky Y, Gendelman HE, Tyor WR. SCID mice with HIV encephalitis develop behavioral abnormalities. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 18: 13-20. PMID 9593453 DOI: 10.1097/00042560-199805010-00003  1
1998 Middaugh LD, McGroarty KK, Groseclose CH, Adinoff B. Cocaine discrimination: relationship to local anesthetics and monoamine uptake inhibitors in C57BL/6 mice. Psychopharmacology. 136: 44-9. PMID 9537681 DOI: 10.1007/S002130050537  1
1998 Groseclose CH, Draughn RA, Tyor WR, Sallee FR, Middaugh LD. Long-term intracranial cannula stabilization in mice with light cured resin composites. Journal of Neuroscience Methods. 79: 31-6. PMID 9531457 DOI: 10.1016/S0165-0270(97)00158-1  1
1997 Kelley BM, Bandy AL, Middaugh LD. A study examining intravenous ethanol-conditioned place preference in C57BL/6J mice. Alcoholism, Clinical and Experimental Research. 21: 1661-6. PMID 9438527 DOI: 10.1111/J.1530-0277.1997.Tb04504.X  1
1997 Kelley BM, Groseclose CH, Middaugh LD. Prenatal cocaine exposure increases the reinforcing strength of oral ethanol in C57 mice. Neurotoxicology and Teratology. 19: 391-8. PMID 9380006 DOI: 10.1016/S0892-0362(97)00022-6  1
1997 Altman-Hamamdzic S, Groseclose C, Ma JX, Hamamdzic D, Vrindavanam NS, Middaugh LD, Parratto NP, Sallee FR. Expression of beta-galactosidase in mouse brain: utilization of a novel nonreplicative Sindbis virus vector as a neuronal gene delivery system. Gene Therapy. 4: 815-22. PMID 9338010 DOI: 10.1038/  1
1997 Kelley BM, Bandy AL, Middaugh LD. A novel chronic and detachable indwelling jugular catheterization procedure for mice. Physiology & Behavior. 62: 163-7. PMID 9226357 DOI: 10.1016/S0031-9384(97)00029-2  1
1997 Halberda JP, Middaugh LD, Gard BE, Jackson BP. DAD1- and DAD2-like agonist effects on motor activity of C57 mice: differences compared to rats. Synapse (New York, N.Y.). 26: 81-92. PMID 9097408 DOI: 10.1002/(Sici)1098-2396(199705)26:1<81::Aid-Syn9>3.0.Co;2-A  1
1997 Groseclose CH, Middaugh LD. The discrimination and durability of an ethanol cue in young and mid-aged female mice. Alcohol (Fayetteville, N.Y.). 14: 191-7. PMID 9085721 DOI: 10.1016/S0741-8329(96)00145-0  1
1997 Kelley BM, Bandy AE, Middaugh LD. A Study Examining Intravenous Ethanol-Conditioned Place Preference in C57BL/6J Mice Alcoholism: Clinical and Experimental Research. 21: 1661-1666. DOI: 10.1111/j.1530-0277.1997.tb04504.x  0.44
1996 Kelley BM, Middaugh LD. Ethanol self-administration and motor deficits in adults C57BL/6J mice exposed prenatally to cocaine. Pharmacology, Biochemistry, and Behavior. 55: 575-84. PMID 8981588 DOI: 10.1016/S0091-3057(96)00289-4  1
1996 Middaugh LD, Boggan WO, Bingel SA, Patrick KS, Xu W. A murine model of prenatal cocaine exposure: effects on the mother and the fetus. Pharmacology, Biochemistry, and Behavior. 55: 565-74. PMID 8981587 DOI: 10.1016/S0091-3057(96)00250-X  1
1996 Miller SR, Middaugh LD, Boggan WO, Patrick KS. Cocaine concentrations in fetal C57BL/6 mouse brain relative to maternal brain and plasma. Neurotoxicology and Teratology. 18: 645-9. PMID 8947941 DOI: 10.1016/S0892-0362(96)00076-1  1
1996 Middaugh LD, Nussbaum R, Ludwicka A, Bolster MB, Silver RM. Cognitive deficits in a murine model of the eosinophilia-myalgia syndrome: a preliminary report. Neurotoxicology and Teratology. 18: 595-601. PMID 8888024 DOI: 10.1016/0892-0362(96)00078-5  1
1996 Xu W, Tyor WR, Middaugh LD, Boggan WO. Cocaine/sex type effects on T lymphocytes: a preliminary report. Drug and Chemical Toxicology. 19: 109-19. PMID 8804556 DOI: 10.3109/01480549609002200  1
1996 Boggan WO, Xu W, Shepherd CL, Middaugh LD. Effects of prenatal ethanol exposure on dopamine systems in C57BL/6J mice. Neurotoxicology and Teratology. 18: 41-8. PMID 8700042 DOI: 10.1016/0892-0362(95)02027-6  1
1995 Gentry GD, Merritt CJ, Middaugh LD. Effects of prenatal maternal ethanol on male offspring progressive-ratio performance and response to amphetamine. Neurotoxicology and Teratology. 17: 673-7. PMID 8747749 DOI: 10.1016/0892-0362(95)02011-X  1
1995 Middaugh LD, Boggan WO. Perinatal maternal ethanol effects on pregnant mice and on offspring viability and growth: influences of exposure time and weaning diet. Alcoholism, Clinical and Experimental Research. 19: 1351-8. PMID 8561314 DOI: 10.1111/J.1530-0277.1995.Tb01624.X  1
1994 Middaugh LD, Boggan WO, Shepherd CL. Prenatal ethanol effects and dopamine systems of adult C57 male mice. Neurotoxicology and Teratology. 16: 207-12. PMID 7914346 DOI: 10.1016/0892-0362(94)90119-8  1
1993 Patrick KS, Boggan WO, Miller SR, Middaugh LD. Gas chromatographic-mass spectrometric determination of plasma and brain cocaine in mice. Journal of Chromatography. 621: 89-94. PMID 8308092 DOI: 10.1016/0378-4347(93)80080-N  1
1992 Hale RL, Randall CL, Becker HC, Middaugh LD. The effect of prenatal ethanol exposure on scentmarking in the C57BL/6J and C3H/He mouse strains. Alcohol (Fayetteville, N.Y.). 9: 287-92. PMID 1637494 DOI: 10.1016/0741-8329(92)90068-L  1
1992 Middaugh LD, Frackelton WF, Boggan WO, Onofrio A, Shepherd CL. Gender differences in the effects of ethanol on C57BL/6 mice. Alcohol (Fayetteville, N.Y.). 9: 257-60. PMID 1605893 DOI: 10.1016/0741-8329(92)90062-F  1
1992 Bao K, Middaugh LD, Becker HC, Shepherd CL. Effects of Ro 15-4513 and ethanol on operant behavior of male and female C57BL/6 mice. Alcohol (Fayetteville, N.Y.). 9: 193-8. PMID 1605885 DOI: 10.1016/0741-8329(92)90052-C  1
1992 Middaugh LD, Gentry GD. Prenatal ethanol effects on reward efficacy for adult mice are gestation stage specific. Neurotoxicology and Teratology. 14: 365-70. PMID 1454046 DOI: 10.1016/0892-0362(92)90044-B  1
1992 Middaugh LD, Bao K, Shepherd CL. Comparative effects of ethanol on motor activity and operant behavior. Pharmacology, Biochemistry, and Behavior. 43: 625-9. PMID 1438501 DOI: 10.1016/0091-3057(92)90202-Q  1
1991 Middaugh LD, Boggan WO. Postnatal growth deficits in prenatal ethanol-exposed mice: characteristics and critical periods. Alcoholism, Clinical and Experimental Research. 15: 919-26. PMID 1789388 DOI: 10.1111/J.1530-0277.1991.Tb05189.X  1
1991 Middaugh LD, Bao K, Becker HC, Daniel SS. Effects of Ro 15-4513 on ethanol discrimination in C57BL/6 mice. Pharmacology, Biochemistry, and Behavior. 38: 763-7. PMID 1651516 DOI: 10.1016/0091-3057(91)90239-X  1
1990 Adams J, Vorhees CV, Middaugh LD. Developmental neurotoxicity of anticonvulsants: human and animal evidence on phenytoin. Neurotoxicology and Teratology. 12: 203-14. PMID 2196420 DOI: 10.1016/0892-0362(90)90092-Q  1
1989 Boggan W, Middaugh L. Effect of central injection of phencyclidine on QNB accumulation and motor activity European Journal of Pharmacology. 166: 123-129. PMID 2792187 DOI: 10.1016/0014-2999(89)90051-4  1
1989 Middaugh LD. Prenatal amphetamine effects on behavior: possible mediation by brain monoamines. Annals of the New York Academy of Sciences. 562: 308-18. PMID 2662861 DOI: 10.1111/J.1749-6632.1989.Tb21028.X  1
1989 Boggan WO, Monroe B, Turner WR, Upshur J, Middaugh LD. Effect of prenatal ethanol administration on the urogenital system of mice. Alcoholism, Clinical and Experimental Research. 13: 206-8. PMID 2658657 DOI: 10.1111/J.1530-0277.1989.Tb00312.X  1
1989 Middaugh LD, Favara JP, Boggan WO. Ethanol stimulation after chronic exposure in C57 mice. Pharmacology, Biochemistry, and Behavior. 34: 331-5. PMID 2622989 DOI: 10.1016/0091-3057(89)90321-3  1
1989 Boggan WO, Middaugh LD, Faught K. Effect of dopaminergic drugs on enhancement of the binding of quinuclidinyl benzilate by phencyclidine in vivo. Neuropharmacology. 28: 617-24. PMID 2569176 DOI: 10.1016/0028-3908(89)90141-X  1
1989 BECKER HC, RANDALL CL, MIDDAUGH LD. Behavioral Teratogenic Effects of Ethanol in Mice Annals of the New York Academy of Sciences. 562: 340-341. DOI: 10.1111/J.1749-6632.1989.Tb21031.X  0.92
1988 Middaugh LD, Randall CL, Favara JP. Prenatal ethanol exposure in C57 mice: effects on pregnancy and offspring development. Neurotoxicology and Teratology. 10: 175-80. PMID 3398826 DOI: 10.1016/0892-0362(88)90082-7  1
1988 Gentry GD, Middaugh LD. Prenatal ethanol weakens the efficacy of reinforcers for adult mice. Teratology. 37: 135-44. PMID 3353863 DOI: 10.1002/Tera.1420370206  1
1988 Frackelton WH, Middaugh LD. Automated acquisition and analysis of animal behavior data utilizing an Apple IIe. Physiology & Behavior. 43: 253-7. PMID 3212066 DOI: 10.1016/0031-9384(88)90249-1  1
1988 Boggan WO, Faught K, Boyd S, Middaugh LD. Parametric studies on phencyclidine enhancement of 3H quinuclidinyl benzilate accumulation in vivo. Pharmacology, Biochemistry, and Behavior. 30: 31-5. PMID 3174753 DOI: 10.1016/0091-3057(88)90421-2  1
1988 Middaugh LD, Favara JP, Boggan WO, Stringer AJ. Discriminative properties of phencyclidine in mice: generalization to ketamine and monohydroxy metabolites. Psychopharmacology. 96: 381-4. PMID 3146772 DOI: 10.1007/Bf00216066  1
1988 Middaugh LD, Ayers KL. Effects of ethanol on mature offspring of mice given ethanol during pregnancy. Alcoholism, Clinical and Experimental Research. 12: 388-93. PMID 3044168 DOI: 10.1111/J.1530-0277.1988.Tb00213.X  1
1987 Buckholtz NS, Middaugh LD. Effects of caffeine and L-phenylisopropyladenosine on locomotor activity of mice. Pharmacology, Biochemistry, and Behavior. 28: 179-85. PMID 3685054 DOI: 10.1016/0091-3057(87)90211-5  1
1987 Middaugh LD, Boggan WO, Randall CL. Stimulatory effects of ethanol in C57BL/6 mice. Pharmacology, Biochemistry, and Behavior. 27: 421-4. PMID 3659065 DOI: 10.1016/0091-3057(87)90343-1  0.72
1987 Boggan WO, Stringer AJ, Faught K, Middaugh LD. Effect of phencyclidine and two monohydroxy metabolites on 3H QNB binding in vivo in rats. Pharmacology, Biochemistry, and Behavior. 26: 847-9. PMID 3602041 DOI: 10.1016/0091-3057(87)90620-4  1
1987 Boggan WO, Middaugh LD. Doubtful role for phencyclidine metabolites in PCP enhancement of QNB binding. Pharmacology, Biochemistry, and Behavior. 26: 671-6. PMID 3602029 DOI: 10.1016/0091-3057(87)90594-6  1
1986 Middaugh LD. Phenobarbital during pregnancy in mouse and man. Neurotoxicology. 7: 287-301. PMID 3785754  1
1985 Buckholtz NS, Freedman DX, Middaugh LD. Daily LSD administration selectively decreases serotonin2 receptor binding in rat brain. European Journal of Pharmacology. 109: 421-5. PMID 3987809 DOI: 10.1016/0014-2999(85)90407-8  1
1985 Middaugh LD, Zemp JW. Dopaminergic mediation of long-term behavioral effects of in utero drug exposure. Neurobehavioral Toxicology and Teratology. 7: 685-9. PMID 3835467  1
1985 Randall CL, Becker HC, Middaugh LD. Effect of prenatal ethanol exposure on activity and shuttle avoidance behavior in adult C57 mice. Alcohol and Drug Research. 6: 351-60. PMID 3834928  1
1983 Middaugh LD, Zemp JW, Boggan WO. Pregnancy increases reactivity of mice to phenobarbital. Science (New York, N.Y.). 220: 534-6. PMID 6836299  1
1983 Middaugh LD, Kapetanovic IM, Sweeney DJ, Ingram DK. Methadone in brain and its effects on locomotor activity of young and aged mice. Neurobiology of Aging. 4: 321-6. PMID 6672639 DOI: 10.1016/0197-4580(83)90009-X  1
1983 Middaugh LD, Ingram DK, Reynolds MA. Methadone effects on locomotor activity of young and aged mice. Neurobiology of Aging. 4: 157-61. PMID 6633785 DOI: 10.1016/0197-4580(83)90041-6  1
1981 Middaugh LD, Blackwell LA, Boggan WO, Zemp JW. Brain concentrations of phenobarbital and behavioral activation or depression. Pharmacology, Biochemistry, and Behavior. 15: 723-8. PMID 7312908 DOI: 10.1016/0091-3057(81)90012-5  1
1981 Middaugh LD, Simpson LW, Thomas TN, Zemp JW. Prenatal maternal phenobarbital increases reactivity and retards habituation of mature offspring to environmental stimuli. Psychopharmacology. 74: 349-52. PMID 6794080 DOI: 10.1007/Bf00432745  1
1981 Middaugh LD, Thomas TN, Simpson LW, Zemp JW. Effects of prenatal maternal injections of phenobarbital on brain neurotransmitters and behavior of young C57 mice. Neurobehavioral Toxicology and Teratology. 3: 271-5. PMID 6117021  1
1981 Platt GE, Middaugh LD. Effect of septal damage on methadone-induced disruption of an operant response in DBA/2J mice Federation Proceedings. 40: 351.  1
1980 Middaugh LD, Simpson LW. Prenatal maternal methadone effects on pregnant C57BL/6 mice and their offspring Neurobehavioral Toxicology and Teratology. 2: 307-313.  1
1979 Tolbert LC, Thomas TN, Middaugh LD, Zemp JW. Ascorbate blocks amphetamine-induced turning behavior in rats with unilateral nigro-striatal lesions. Brain Research Bulletin. 4: 43-8. PMID 572739 DOI: 10.1016/0361-9230(79)90056-X  1
1979 Middaugh LD, Boggan WO, Wilson-Burrows C, Zemp JW. Prenatal maternal phenobarbital alters plasma concentrations of corticosterone in developing offspring. Life Sciences. 24: 999-1002. PMID 571948 DOI: 10.1016/0024-3205(79)90318-7  1
1979 Tolbert LC, Thomas TN, Middaugh LD, Zemp JW. Effect of ascorbic acid on neurochemical, behavioral, and physiological systems mediated by catecholamines. Life Sciences. 25: 2189-95. PMID 542096 DOI: 10.1016/0024-3205(79)90091-2  1
1979 Boggan WO, Meyer JS, Middaugh LD, Sparks DL. Ethanol, calcium, and naloxone in mice. Alcoholism, Clinical and Experimental Research. 3: 158-61. PMID 391077 DOI: 10.1111/J.1530-0277.1979.Tb05290.X  1
1978 Middaugh LD, Read E, Boggan WO. Effects of naloxone on ethanol induced alterations of locomotor activity in C57BL/6 mice. Pharmacology, Biochemistry, and Behavior. 9: 157-60. PMID 714965 DOI: 10.1016/0091-3057(78)90158-2  1
1978 Middaugh LD, Santos CA. Effects of methadone on behavior maintained by fixed ratio reinforcement schedules. Pharmacology, Biochemistry, and Behavior. 8: 521-6. PMID 674258 DOI: 10.1016/0091-3057(78)90381-7  1
1977 Tolbert L, Thomas TN, Middaugh LD. Ascorbate attenuates apomorphine induced hypothermia in vivo Pharmacologist. 19: No. 160.  1
1976 Middaugh LD, Zemp JW. Effects of methadone on activity and on brain monoamines in two strains of mice. Pharmacology, Biochemistry, and Behavior. 5: 367-70. PMID 996068 DOI: 10.1016/0091-3057(76)90091-5  1
1976 Middaugh LD, Grover TA, Blackwell LA, Zemp JW. Neurochemical and behavioral effects of diet related perinatal folic acid restriction. Pharmacology, Biochemistry, and Behavior. 5: 129-34. PMID 996047 DOI: 10.1016/0091-3057(76)90027-7  1
1976 Zemp JW, Middaugh LD, Grover TA, Blackwell LA. Effect of dietary folic acid deprivation on folate levels in brain, liver, and plasma of DBA/2J mice Nutrition Reports International. 14: 1-6.  1
1975 Middaugh LD, Santos CA, Zemp JW. Effects of phenobarbital given to pregnant mice on behavior of mature offspring. Developmental Psychobiology. 8: 305-13. PMID 1225697 DOI: 10.1002/Dev.420080404  1
1975 Middaugh LD, Santos CA, Zemp JW. Phenobarbital during pregnancy alters operant behavior of offspring in C57BL/6J mice. Pharmacology, Biochemistry, and Behavior. 3: 1137-9. PMID 1223902 DOI: 10.1016/0091-3057(75)90030-1  1
1975 Zemp JW, Middaugh LD. Some effects of prenatal exposure to d-amphetamine sulfate and phenobarbital on developmental neurochemistry and on behavior. Addictive Diseases. 2: 307-31. PMID 1163369  1
1974 Middaugh LD, Blackwell LA, Santos CA, Zemp JW. Effects of d-amphetamine sulfate given to pregnant mice on activity and on catecholamines in the brains of offspring. Developmental Psychobiology. 7: 429-38. PMID 4426470 DOI: 10.1002/Dev.420070507  1
1972 Middaugh LD, Hurwitz HM, Knapp TM, Huchinson W. The effect of septal lesions in rats on performance of a free-operant avoidance task. Physiology & Behavior. 9: 59-62. PMID 5080157 DOI: 10.1016/0031-9384(72)90265-X  1
1971 Lubar JF, Middaugh LD. Avoidance conditioning in cats with striate and auditory cortex lesions and contrasting effects of peripheral blindness. Journal of Comparative and Physiological Psychology. 76: 26-30. PMID 5559604 DOI: 10.1037/H0031041  0.92
1970 Middaugh LD, Lubar JF. Interaction of septal lesions and experience on the suppression of punished responses. Physiology & Behavior. 5: 233-7. PMID 5525801 DOI: 10.1016/0031-9384(70)90071-5  0.92
1969 Golden GH, Middaugh LD, Lubar JF. Stereotaxic presentation of subcortical aspiration 1 Behavior Research Methods & Instrumentation. 1: 295-297. DOI: 10.3758/Bf03209919  0.92
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