Richard B. Carter - Publications

Merck Research Laboratories, Boston, MA, United States 
behavioral pharmacology, drug discovery, drug development

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Witkin JM, Gleason SD, Carter RB, Dykstra LA. Obituary: J. David LEander, Ph.D. : (April 8, 1944-November 14, 2014). Psychopharmacology. 232: 1175-6. PMID 25697862 DOI: 10.1007/S00213-015-3885-2  0.76
2006 Ilyin VI, Pomonis JD, Whiteside GT, Harrison JE, Pearson MS, Mark L, Turchin PI, Gottshall S, Carter RB, Nguyen P, Hogenkamp DJ, Olanrewaju S, Benjamin E, Woodward RM. Pharmacology of 2-[4-(4-chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide: a potent, broad-spectrum state-dependent sodium channel blocker for treating pain states. The Journal of Pharmacology and Experimental Therapeutics. 318: 1083-93. PMID 16728593 DOI: 10.1124/Jpet.106.104737  1
2005 Ilyin VI, Hodges DD, Whittemore ER, Carter RB, Cai SX, Woodward RM. V102862 (Co 102862): a potent, broad-spectrum state-dependent blocker of mammalian voltage-gated sodium channels. British Journal of Pharmacology. 144: 801-12. PMID 15778702 DOI: 10.1038/Sj.Bjp.0706058  1
2004 Shao B, Victory S, Ilyin VI, Goehring RR, Sun Q, Hogenkamp D, Hodges DD, Islam K, Sha D, Zhang C, Nguyen P, Robledo S, Sakellaropoulos G, Carter RB. Phenoxyphenyl pyridines as novel state-dependent, high-potency sodium channel inhibitors. Journal of Medicinal Chemistry. 47: 4277-85. PMID 15293999 DOI: 10.1021/Jm040048D  1
2004 Yang J, Gharagozloo P, Yao J, Ilyin VI, Carter RB, Nguyen P, Robledo S, Woodward RM, Hogenkamp DJ. 3-(4-phenoxyphenyl)pyrazoles: a novel class of sodium channel blockers. Journal of Medicinal Chemistry. 47: 1547-52. PMID 14998340 DOI: 10.1021/Jm030498Q  1
2003 Kaminski RM, Gasior M, Carter RB, Witkin JM. Protective efficacy of neuroactive steroids against cocaine kindled-seizures in mice. European Journal of Pharmacology. 474: 217-22. PMID 12921865 DOI: 10.1016/S0014-2999(03)02086-7  1
2003 Mattson RJ, Catt JD, Sloan CP, Gao Q, Carter RB, Gentile A, Mahle CD, Matos FF, McGovern R, VanderMaelen CP, Yocca FD. Development of a presynaptic 5-HT1A antagonist. Bioorganic & Medicinal Chemistry Letters. 13: 285-8. PMID 12482441 DOI: 10.1016/S0960-894X(02)00879-X  1
2001 Vanover KE, Hogenkamp DJ, Lan NC, Gee KW, Carter RB. Behavioral characterization of Co 134444 (3alpha-hydroxy-21-(1'-imidazolyl)-3beta-methoxymethyl-5alpha- pregnan-20-one), a novel sedative-hypnotic neuroactive steroid. Psychopharmacology. 155: 285-91. PMID 11432691 DOI: 10.1007/S002130100695  1
2000 Vanover KE, Rosenzweig-Lipson S, Hawkinson JE, Lan NC, Belluzzi JD, Stein L, Barrett JE, Wood PL, Carter RB. Characterization of the anxiolytic properties of a novel neuroactive steroid, Co 2-6749 (GMA-839; WAY-141839; 3alpha, 21-dihydroxy-3beta-trifluoromethyl-19-nor-5beta-pregnan-20-one), a selective modulator of gamma-aminobutyric acid(A) receptors. The Journal of Pharmacology and Experimental Therapeutics. 295: 337-45. PMID 10991999  1
2000 Ungard JT, Beekman M, Gasior M, Carter RB, Dijkstra D, Witkin JM. Modification of behavioral effects of drugs in mice by neuroactive steroids. Psychopharmacology. 148: 336-43. PMID 10928304 DOI: 10.1007/S002130050060  1
2000 Vanover KE, Suruki M, Huber M, Wilent WB, Carter RB. Neuroactive steroids attenuate cocaine-induced sucrose intake in rats, but not cocaine-induced hyperactivity in mice. Psychopharmacology. 149: 269-76. PMID 10823408 DOI: 10.1007/s002139900350  1
2000 Gasior M, Ungard JT, Beekman M, Carter RB, Witkin JM. Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure-kindled mice: comparison with diazepam and valproate. Neuropharmacology. 39: 1184-96. PMID 10760361 DOI: 10.1016/S0028-3908(99)00190-2  1
1999 Vanover KE, Edgar DM, Seidel WF, Hogenkamp DJ, Fick DB, Lan NC, Gee KW, Carter RB. Response-rate suppression in operant paradigm as predictor of soporific potency in rats and identification of three novel sedative-hypnotic neuroactive steroids. The Journal of Pharmacology and Experimental Therapeutics. 291: 1317-23. PMID 10565857  1
1999 Vanover KE, Robledo S, Huber M, Carter RB. Pharmacological evaluation of a modified conflict procedure: punished drinking in non-water-deprived rats. Psychopharmacology. 145: 333-41. PMID 10494583 DOI: 10.1007/S002130051066  1
1999 Rowlett JK, Winger G, Carter RB, Wood PL, Woods JH, Woolverton WL. Reinforcing and discriminative stimulus effects of the neuroactive steroids pregnanolone and Co 8-7071 in rhesus monkeys. Psychopharmacology. 145: 205-12. PMID 10463322 DOI: 10.1007/S002130051050  1
1999 Gasior M, Carter RB, Witkin JM. Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders. Trends in Pharmacological Sciences. 20: 107-12. PMID 10203866 DOI: 10.1016/S0165-6147(99)01318-8  1
1999 Vanover KE, Suruki M, Robledo S, Huber M, Wieland S, Lan NC, Gee KW, Wood PL, Carter RB. Positive allosteric modulators of the GABA(A) receptor: differential interaction of benzodiazepines and neuroactive steroids with ethanol. Psychopharmacology. 141: 77-82. PMID 9952068 DOI: 10.1007/S002130050809  1
1998 Hawkinson JE, Acosta-Burruel M, Yang KC, Hogenkamp DJ, Chen JS, Lan NC, Drewe JA, Whittemore ER, Woodward RM, Carter RB, Upasani RB. Substituted 3beta-phenylethynyl derivatives of 3alpha-hydroxy-5alpha-pregnan-20-one: remarkably potent neuroactive steroid modulators of gamma-aminobutyric acidA receptors. The Journal of Pharmacology and Experimental Therapeutics. 287: 198-207. PMID 9765338  1
1998 Wang Y, Konkoy CS, Ilyin VI, Vanover KE, Carter RB, Weber E, Keana JF, Woodward RM, Cai SX. Synthesis of 7,8-(methylenedioxy)-1-phenyl-3,5-dihydro-4H-2, 3-benzodiazepin-4-ones as novel and potent noncompetitive AMPA receptor antagonists. Journal of Medicinal Chemistry. 41: 2621-5. PMID 9651166 DOI: 10.1021/Jm980168J  1
1998 Beekman M, Ungard JT, Gasior M, Carter RB, Dijkstra D, Goldberg SR, Witkin JM. Reversal of behavioral effects of pentylenetetrazol by the neuroactive steroid ganaxolone. The Journal of Pharmacology and Experimental Therapeutics. 284: 868-77. PMID 9495844  1
1998 Gasior M, Beekman M, Carter RB, Goldberg SR, Witkin JM. Antiepileptogenic effects of the novel synthetic neuroactive steroid, ganaxolone, against pentylenetetrazol-induced kindled seizures: Comparison with diazepam and valproate Drug Development Research. 44: 21-33. DOI: 10.1002/(Sici)1098-2299(199805)44:1<21::Aid-Ddr4>3.0.Co;2-R  1
1997 Gasior M, Carter RB, Goldberg SR, Witkin JM. Anticonvulsant and behavioral effects of neuroactive steroids alone and in conjunction with diazepam. The Journal of Pharmacology and Experimental Therapeutics. 282: 543-53. PMID 9262314  1
1997 Edgar DM, Seidel WF, Gee KW, Lan NC, Field G, Xia H, Hawkinson JE, Wieland S, Carter RB, Wood PL. CCD-3693: an orally bioavailable analog of the endogenous neuroactive steroid, pregnanolone, demonstrates potent sedative hypnotic actions in the rat. The Journal of Pharmacology and Experimental Therapeutics. 282: 420-9. PMID 9223583  1
1997 Carter RB, Wood PL, Wieland S, Hawkinson JE, Belelli D, Lambert JJ, White HS, Wolf HH, Mirsadeghi S, Tahir SH, Bolger MB, Lan NC, Gee KW. Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor. The Journal of Pharmacology and Experimental Therapeutics. 280: 1284-95. PMID 9067315  1
1997 Upasani RB, Yang KC, Acosta-Burruel M, Konkoy CS, McLellan JA, Woodward RM, Lan NC, Carter RB, Hawkinson JE. 3 alpha-Hydroxy-3 beta-(phenylethynyl)-5 beta-pregnan-20-ones: synthesis and pharmacological activity of neuroactive steroids with high affinity for GABAA receptors. Journal of Medicinal Chemistry. 40: 73-84. PMID 9016330 DOI: 10.1021/Jm9605344  1
1995 Taylor DP, Carter RB, Eison AS, Mullins UL, Smith HL, Torrente JR, Wright RN, Yocca FD. Pharmacology and neurochemistry of nefazodone, a novel antidepressant drug. The Journal of Clinical Psychiatry. 56: 3-11. PMID 7649970  1
1991 Carter RB, Francis WR. Capsaicin desensitization to plasma extravasation evoked by antidromic C-fiber stimulation is not associated with antinociception in the rat. Neuroscience Letters. 127: 43-5. PMID 1881616 DOI: 10.1016/0304-3940(91)90890-6  1
1991 Carter RB. Differentiating analgesic and non-analgesic drug activities on rat hot plate: effect of behavioral endpoint. Pain. 47: 211-20. PMID 1762817 DOI: 10.1016/0304-3959(91)90207-E  1
1991 Carter RB. Topical capsaicin in the treatment of cutaneous disorders Drug Development Research. 22: 109-123.  1
1990 Katz JL, Dworkin SI, Dykstra LA, Carter RB, Witkin JM. Some behavioral effects of repeated d-amphetamine administrations Drug Development Research. 20: 31-41. DOI: 10.1002/Ddr.430200105  1
1985 Carter RB, Dykstra LA. Effects of picenadol (LY150720) and its stereoisomers on electric shock titration in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 234: 299-306. PMID 4020674  1
1985 Carter RB, Thompson DM. Effects of phencyclidine (PCP), lysergic acid diethylamide (LSD) and methylenedioxyamphetamine (MDA) on acquisition of response sequences Federation Proceedings. 44: No. 1833.  1
1984 Carter RB, Leander JD. Comparison of the effects of naloxone and picrotoxin on schedule-controlled responding in the pigeon: possible GABA-antagonistic effects of naloxone. The Journal of Pharmacology and Experimental Therapeutics. 230: 40-6. PMID 6747830  1
1984 Ervin GN, Carter RB, Webster EL, Moore SI, Cooper BR. Evidence that taste aversion learning induced by l-5-hydroxytryptophan is mediated peripherally. Pharmacology, Biochemistry, and Behavior. 20: 799-802. PMID 6610880 DOI: 10.1016/0091-3057(84)90202-8  1
1984 Leander JD, Carter RB. Effects of norepinephrine and serotonin uptake inhibitors on the schedule-controlled behavior of the pigeon. Pharmacology, Biochemistry, and Behavior. 20: 391-5. PMID 6608736 DOI: 10.1016/0091-3057(84)90277-6  1
1984 Carter RB, Dykstra LA. Quantitative analysis of the interaction between the agonist and antagonist isomers of picenadol (LY150720) on electric shock titration in the squirrel monkey. European Journal of Pharmacology. 106: 469-76. PMID 6519173 DOI: 10.1016/0014-2999(84)90050-5  1
1984 Carter RB, Dykstra LA. Effects of LY150720 (picenadol), a novel mixed-action opioid, on schedule-controlled responding in the squirrel monkey. Pharmacology, Biochemistry, and Behavior. 21: 779-86. PMID 6514768 DOI: 10.1016/S0091-3057(84)80019-2  1
1984 Carter RB, Dykstra LA. Effects of LY150720 (picenadol), a novel mixed-action opioid on schedule-controlled responding in the squirrel monkey Federation Proceedings. 43: no. 2702.  1
1982 Witkin JM, Dykstra LA, Carter RB. Acute tolerance to the discriminative stimulus properties of morphine. Pharmacology, Biochemistry, and Behavior. 17: 223-8. PMID 7134234 DOI: 10.1016/0091-3057(82)90073-9  1
1982 Leander JD, Carter RB. Attenuation of normeperidine's suppressing effect on schedule-controlled behavior. European Journal of Pharmacology. 81: 107-10. PMID 7117363 DOI: 10.1016/0014-2999(82)90606-9  1
1982 Carter RB, Leander JD. Discriminative stimulus properties of naloxone. Psychopharmacology. 77: 305-8. PMID 6291084 DOI: 10.1007/Bf00432760  1
1982 Carter RB, Leander JD, Dykstra LA. Contribution of normeperidine to the analgesic effects of meperidine Federation Proceedings. 41: No. 6107.  1
1981 Carter RB, Leander JD. Comparison of serotonergic agonists as inducers of taste aversions Federation Proceedings. 40: 177.  1
1980 Carter RB, Leander JD. Evidence for a peripheral effect of sertonin or metabolites in 5-hydroxytryptophan-induced hypothermia. Neuropharmacology. 19: 777-84. PMID 6968413 DOI: 10.1016/0028-3908(80)90070-2  1
1980 Witkin JM, Carter RB, Dykstra LA. Discriminative stimulus properties of d-amphetamine-pentobarbital combinations. Psychopharmacology. 68: 269-76. PMID 6771810 DOI: 10.1007/BF00428114  1
1980 Carter RB, Harden TK, Leander JD. Effect of meperidine and analogues on 3H-quinuclidinyl benzilate (3H-QNB) binding in rat brain Pharmacologist. 22: No.797.  1
1980 Carter RB, Leander JD. Chronic low-level lead exposure: Effects on schedule-controlled responding revealed by drug challenge Neurobehavioral Toxicology and Teratology. 2: 345-353.  1
1979 Carter RB, Leander JD. Evidence for a peripheral effect of serotonin or metabolites in 5-hydroxytryptophan (5-HTP)-induced hypothermia Federation Proceedings. 38: No. 2430.  1
1978 Carter RB, Dykstra LA, Leander JD, Appel JB. Role of peripheral mechanisms in the behavioral effects of 5-hydroxytryptophan. Pharmacology, Biochemistry, and Behavior. 9: 249-53. PMID 309609 DOI: 10.1016/0091-3057(78)90172-7  1
1978 Carter RB, Appel JB. LSD and 5-HTP: tolerance and cross-tolerance relationships. European Journal of Pharmacology. 50: 145-8. PMID 308008 DOI: 10.1016/0014-2999(78)90010-9  1
1978 Carter RB, Dykstra LA, Leander JD, Appel JB. 5-Hydroxytryptophan (5-HTP) on operant responding: evidence for a peripheral effect Federation Proceedings. 37: No. 3734.  1
1978 Carter RB, Leander JD. Attenuation of the effects of naloxone on schedule-controlled responding of pigeons by pentobarbital Pharmacologist. 20: 408.  1
1976 Carter RB, Appel JB. Blockade of the behavioral effects of 5-HTP by the decarboxylase inhibitor Ro 4-4602. Pharmacology, Biochemistry, and Behavior. 4: 407-9. PMID 935212 DOI: 10.1016/0091-3057(76)90056-3  1
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