Ramesh Raghupathi - Publications

Affiliations: 
Drexel University, Philadelphia, PA, United States 

120 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hanlon LA, Raghupathi R, Huh JW. Depletion of microglia immediately following traumatic brain injury in the pediatric rat: Implications for cellular and behavioral pathology. Experimental Neurology. PMID 30980832 DOI: 10.1016/j.expneurol.2019.04.004  0.48
2018 Huh JW, Raghupathi R. Therapeutic strategies to target acute and long-term sequelae of pediatric traumatic brain injury. Neuropharmacology. PMID 29933010 DOI: 10.1016/j.neuropharm.2018.06.025  0.48
2017 Raghupathi R, Huh JW. Age-at-injury effects of microglial activation following traumatic brain injury: implications for treatment strategies. Neural Regeneration Research. 12: 741-742. PMID 28616025 DOI: 10.4103/1673-5374.206639  0.48
2016 Fischer I, Haas C, Raghupathi R, Jin Y. Spinal cord concussion: studying the potential risks of repetitive injury. Neural Regeneration Research. 11: 58-60. PMID 26981079 DOI: 10.4103/1673-5374.169634  1
2016 Lamprecht MR, Elkin BS, Kesavabhotla K, Crary JF, Hammers JL, Huh JW, Raghupathi R, Morrison Iii B. Strong correlation of genome-wide expression after traumatic brain injury in vitro and in vivo implicates a role for SORLA. Journal of Neurotrauma. PMID 26919808 DOI: 10.1089/neu.2015.4306  0.48
2016 Hanlon LA, Huh JW, Raghupathi R. Minocycline Transiently Reduces Microglia/Macrophage Activation but Exacerbates Cognitive Deficits Following Repetitive Traumatic Brain Injury in the Neonatal Rat. Journal of Neuropathology and Experimental Neurology. PMID 26825312 DOI: 10.1093/jnen/nlv021  1
2015 Wang H, Sang N, Zhang C, Raghupathi R, Tanzi RE, Saunders A. Correction to Cathepsin L Mediates the Degradation of Novel APP C-Terminal Fragments. Biochemistry. PMID 26348101 DOI: 10.1021/acs.biochem.5b00968  0.88
2015 Fontana AC, Fox DP, Zoubroulis A, Mortensen OV, Raghupathi R. Neuroprotective effects of the glutamate transporter activator, MS-153, following traumatic brain injury in the adult rat. Journal of Neurotrauma. PMID 26200170 DOI: 10.1089/neu.2015.4079  1
2015 Margulies SS, Anderson GD, Atif F, Badaut J, Clark RS, Empey P, Guseva M, Hoane MR, Huh JW, Pauly JR, Raghupathi R, Scheff S, Stein D, Tang H, Hicks M. Combination Therapies for Traumatic Brain Injury: Retrospective Considerations. Journal of Neurotrauma. PMID 25970337 DOI: 10.1089/neu.2014.3855  1
2015 Wang H, Sang N, Zhang C, Raghupathi R, Tanzi RE, Saunders A. Cathepsin L Mediates the Degradation of Novel APP C-Terminal Fragments. Biochemistry. 54: 2806-16. PMID 25910068 DOI: 10.1021/acs.biochem.5b00329  1
2014 Lowing JL, Susick LL, Caruso JP, Provenzano AM, Raghupathi R, Conti AC. Experimental traumatic brain injury alters ethanol consumption and sensitivity. Journal of Neurotrauma. 31: 1700-10. PMID 24934382 DOI: 10.1089/neu.2013.3286  1
2013 Mallard C, Raghupathi R. Preface. Developmental Neuroscience. 35: 87. PMID 23796853 DOI: 10.1159/000353264  1
2012 Dileonardi AM, Huh JW, Raghupathi R. Differential effects of FK506 on structural and functional axonal deficits after diffuse brain injury in the immature rat. Journal of Neuropathology and Experimental Neurology. 71: 959-72. PMID 23095847 DOI: 10.1097/NEN.0b013e31826f5876  1
2011 Armstead WM, Raghupathi R. Endothelin and the neurovascular unit in pediatric traumatic brain injury. Neurological Research. 33: 127-32. PMID 21801587 DOI: 10.1179/016164111X12881719352138  1
2011 Creed JA, DiLeonardi AM, Fox DP, Tessler AR, Raghupathi R. Concussive brain trauma in the mouse results in acute cognitive deficits and sustained impairment of axonal function. Journal of Neurotrauma. 28: 547-63. PMID 21299360 DOI: 10.1089/neu.2010.1729  1
2011 Huh JW, Widing AG, Raghupathi R. Differential effects of injury severity on cognition and cellular pathology after contusive brain trauma in the immature rat. Journal of Neurotrauma. 28: 245-57. PMID 21091272 DOI: 10.1089/neu.2010.1639  1
2010 Tomasevic G, Raghupathi R, Scherbel U, Wieloch T, McIntosh TK. Deletion of the p53 tumor suppressor gene improves neuromotor function but does not attenuate regional neuronal cell loss following experimental brain trauma in mice. Journal of Neuroscience Research. 88: 3414-23. PMID 20890990 DOI: 10.1002/jnr.22491  1
2010 Kilbaugh TJ, Friess SH, Raghupathi R, Huh JW. Sedation and analgesia in children with developmental disabilities and neurologic disorders. International Journal of Pediatrics. 2010. PMID 20706547 DOI: 10.1155/2010/189142  0.48
2010 Saatman KE, Creed J, Raghupathi R. Calpain as a therapeutic target in traumatic brain injury. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 7: 31-42. PMID 20129495 DOI: 10.1016/j.nurt.2009.11.002  1
2009 Huh JW, Raghupathi R. New concepts in treatment of pediatric traumatic brain injury. Anesthesiology Clinics. 27: 213-40. PMID 19703674 DOI: 10.1016/j.anclin.2009.05.006  1
2009 DiLeonardi AM, Huh JW, Raghupathi R. Impaired axonal transport and neurofilament compaction occur in separate populations of injured axons following diffuse brain injury in the immature rat. Brain Research. 1263: 174-82. PMID 19368848 DOI: 10.1016/j.brainres.2009.01.021  1
2008 Huh JW, Widing AG, Raghupathi R. Midline brain injury in the immature rat induces sustained cognitive deficits, bihemispheric axonal injury and neurodegeneration. Experimental Neurology. 213: 84-92. PMID 18599043 DOI: 10.1016/j.expneurol.2008.05.009  1
2008 Conte V, Raghupathi R, Watson DJ, Fujimoto S, Royo NC, Marklund N, Stocchetti N, McIntosh TK. TrkB gene transfer does not alter hippocampal neuronal loss and cognitive deficits following traumatic brain injury in mice. Restorative Neurology and Neuroscience. 26: 45-56. PMID 18431005  1
2007 Raghupathi R, Huh JW. Diffuse brain injury in the immature rat: evidence for an age-at-injury effect on cognitive function and histopathologic damage. Journal of Neurotrauma. 24: 1596-608. PMID 17970623 DOI: 10.1089/neu.2007.3790  1
2007 Huh JW, Raghupathi R. Chronic cognitive deficits and long-term histopathological alterations following contusive brain injury in the immature rat. Journal of Neurotrauma. 24: 1460-74. PMID 17892408 DOI: 10.1089/neu.2006.3787  1
2007 Serbest G, Burkhardt MF, Siman R, Raghupathi R, Saatman KE. Temporal profiles of cytoskeletal protein loss following traumatic axonal injury in mice. Neurochemical Research. 32: 2006-14. PMID 17401646 DOI: 10.1007/s11064-007-9318-9  1
2007 Huh JW, Widing AG, Raghupathi R. Basic science; repetitive mild non-contusive brain trauma in immature rats exacerbates traumatic axonal injury and axonal calpain activation: a preliminary report. Journal of Neurotrauma. 24: 15-27. PMID 17263667 DOI: 10.1089/neu.2006.0072  1
2007 Shimizu S, Khan MZ, Hippensteel RL, Parkar A, Raghupathi R, Meucci O. Role of the transcription factor E2F1 in CXCR4-mediated neurotoxicity and HIV neuropathology. Neurobiology of Disease. 25: 17-26. PMID 17011204 DOI: 10.1016/j.nbd.2006.08.004  1
2006 Johnson VE, Murray L, Raghupathi R, Stewart J, Nicoll JA, MacKinnon MA, McIntosh TK, Graham DI. No evidence for the presence of apolipoprotein epsilon4, interleukin-lalpha allele 2 and interleukin-1beta allele 2 cause an increase in programmed cell death following traumatic brain injury in humans. Clinical Neuropathology. 25: 255-64. PMID 17140155  1
2006 Levchakov A, Linder-Ganz E, Raghupathi R, Margulies SS, Gefen A. Computational studies of strain exposures in neonate and mature rat brains during closed head impact. Journal of Neurotrauma. 23: 1570-80. PMID 17020491 DOI: 10.1089/neu.2006.23.1570  1
2006 Martin HA, Woodson A, Christian CW, Helfaer MA, Raghupathi R, Huh JW. Shaken baby syndrome. Critical Care Nursing Clinics of North America. 18: 279-86. PMID 16962449 DOI: 10.1016/j.ccell.2006.05.001  1
2006 Huh JW, Franklin MA, Widing AG, Raghupathi R. Regionally distinct patterns of calpain activation and traumatic axonal injury following contusive brain injury in immature rats. Developmental Neuroscience. 28: 466-76. PMID 16943669 DOI: 10.1159/000094172  1
2006 Saatman KE, Feeko KJ, Pape RL, Raghupathi R. Differential behavioral and histopathological responses to graded cortical impact injury in mice. Journal of Neurotrauma. 23: 1241-53. PMID 16928182 DOI: 10.1089/neu.2006.23.1241  1
2006 DeRidder MN, Simon MJ, Siman R, Auberson YP, Raghupathi R, Meaney DF. Traumatic mechanical injury to the hippocampus in vitro causes regional caspase-3 and calpain activation that is influenced by NMDA receptor subunit composition. Neurobiology of Disease. 22: 165-76. PMID 16356733 DOI: 10.1016/j.nbd.2005.10.011  1
2005 Tkacs NC, Pan Y, Raghupathi R, Dunn-Meynell AA, Levin BE. Cortical Fluoro-Jade staining and blunted adrenomedullary response to hypoglycemia after noncoma hypoglycemia in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 1645-55. PMID 15902194 DOI: 10.1038/sj.jcbfm.9600152  1
2005 Longhi L, Saatman KE, Fujimoto S, Raghupathi R, Meaney DF, Davis J, McMillan B S A, Conte V, Laurer HL, Stein S, Stocchetti N, McIntosh TK. Temporal window of vulnerability to repetitive experimental concussive brain injury. Neurosurgery. 56: 364-74; discussion 3. PMID 15670384 DOI: 10.1227/01.NEU.0000149008.73513.44  1
2005 Gefen A, Levchakov A, Linder-Ganz E, Margulies SS, Raghupathi R. Strain distribution in brain tissue of rats subjected to closed head injury is age-dependent Proceedings of the 2005 Summer Bioengineering Conference. 2005: 141-142.  1
2004 Longhi L, Watson DJ, Saatman KE, Thompson HJ, Zhang C, Fujimoto S, Royo N, Castelbuono D, Raghupathi R, Trojanowski JQ, Lee VM, Wolfe JH, Stocchetti N, McIntosh TK. Ex vivo gene therapy using targeted engraftment of NGF-expressing human NT2N neurons attenuates cognitive deficits following traumatic brain injury in mice. Journal of Neurotrauma. 21: 1723-36. PMID 15684764 DOI: 10.1089/neu.2004.21.1723  1
2004 Strauss KI, Narayan RK, Raghupathi R. Common patterns of bcl-2 family gene expression in two traumatic brain injury models. Neurotoxicity Research. 6: 333-42. PMID 15545017 DOI: 10.1007/BF03033444  1
2004 Lenzlinger PM, Saatman KE, Hoover RC, Cheney JA, Bareyre FM, Raghupathi R, Arnold LD, McIntosh TK. Inhibition of vascular endothelial growth factor receptor (VEGFR) signaling by BSF476921 attenuates regional cerebral edema following traumatic brain injury in rats. Restorative Neurology and Neuroscience. 22: 73-9. PMID 15272142  1
2004 Otori T, Friedland JC, Sinson G, McIntosh TK, Raghupathi R, Welsh FA. Traumatic brain injury elevates glycogen and induces tolerance to ischemia in rat brain. Journal of Neurotrauma. 21: 707-18. PMID 15253799 DOI: 10.1089/0897715041269623  1
2004 Raghupathi R. Cell death mechanisms following traumatic brain injury. Brain Pathology (Zurich, Switzerland). 14: 215-22. PMID 15193035  1
2004 Raghupathi R, Mehr MF, Helfaer MA, Margulies SS. Traumatic axonal injury is exacerbated following repetitive closed head injury in the neonatal pig. Journal of Neurotrauma. 21: 307-16. PMID 15115605 DOI: 10.1089/089771504322972095  1
2004 Wilson S, Raghupathi R, Saatman KE, MacKinnon MA, McIntosh TK, Graham DI. Continued in situ DNA fragmentation of microglia/macrophages in white matter weeks and months after traumatic brain injury. Journal of Neurotrauma. 21: 239-50. PMID 15115599 DOI: 10.1089/089771504322972031  1
2004 Marciano PG, Brettschneider J, Manduchi E, Davis JE, Eastman S, Raghupathi R, Saatman KE, Speed TP, Stoeckert CJ, Eberwine JH, McIntosh TK. Neuron-specific mRNA complexity responses during hippocampal apoptosis after traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2866-76. PMID 15044525 DOI: 10.1523/JNEUROSCI.5051-03.2004  1
2003 Gefen A, Gefen N, Zhu Q, Raghupathi R, Margulies SS. Age-dependent changes in material properties of the brain and braincase of the rat. Journal of Neurotrauma. 20: 1163-77. PMID 14651804 DOI: 10.1089/089771503770802853  1
2003 Huh JW, Raghupathi R, Laurer HL, Helfaer MA, Saatman KE. Transient loss of microtubule-associated protein 2 immunoreactivity after moderate brain injury in mice. Journal of Neurotrauma. 20: 975-84. PMID 14588114 DOI: 10.1089/089771503770195821  1
2003 Raghupathi R, Muir JK, Fulp CT, Pittman RN, McIntosh TK. Acute activation of mitogen-activated protein kinases following traumatic brain injury in the rat: implications for posttraumatic cell death. Experimental Neurology. 183: 438-48. PMID 14552884 DOI: 10.1016/S0014-4886(03)00166-3  1
2003 Raghupathi R, Strauss KI, Zhang C, Krajewski S, Reed JC, McIntosh TK. Temporal alterations in cellular Bax:Bcl-2 ratio following traumatic brain injury in the rat. Journal of Neurotrauma. 20: 421-35. PMID 12803975 DOI: 10.1089/089771503765355504  1
2003 Thompson HJ, Tkacs NC, Saatman KE, Raghupathi R, McIntosh TK. Hyperthermia following traumatic brain injury: a critical evaluation. Neurobiology of Disease. 12: 163-73. PMID 12742737 DOI: 10.1016/S0969-9961(02)00030-X  1
2003 Lifshitz J, Friberg H, Neumar RW, Raghupathi R, Welsh FA, Janmey P, Saatman KE, Wieloch T, Grady MS, McIntosh TK. Structural and functional damage sustained by mitochondria after traumatic brain injury in the rat: evidence for differentially sensitive populations in the cortex and hippocampus. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 219-31. PMID 12571453  1
2002 Riess P, Zhang C, Saatman KE, Laurer HL, Longhi LG, Raghupathi R, Lenzlinger PM, Lifshitz J, Boockvar J, Neugebauer E, Snyder EY, McIntosh TK. Transplanted neural stem cells survive, differentiate, and improve neurological motor function after experimental traumatic brain injury. Neurosurgery. 51: 1043-52; discussion . PMID 12234415 DOI: 10.1097/00006123-200210000-00035  1
2002 Laurer HL, Ritting AN, Russ AB, Bareyre FM, Raghupathi R, Saatman KE. Effects of underwater sound exposure on neurological function and brain histology. Ultrasound in Medicine & Biology. 28: 965-73. PMID 12208341 DOI: 10.1016/S0301-5629(02)00526-4  1
2002 Raghupathi R, Margulies SS. Traumatic axonal injury after closed head injury in the neonatal pig. Journal of Neurotrauma. 19: 843-53. PMID 12184854 DOI: 10.1089/08977150260190438  1
2002 Fowler J, MacKinnon MA, Raghupathi R, Saatman KE, McIntosh TK, Graham DI. Age does not influence DNA fragmentation in the hippocampus after fatal traumatic brain injury in young and aged humans compared with controls. Clinical Neuropathology. 21: 156-62. PMID 12143927  1
2002 Huh JW, Laurer HL, Raghupathi R, Helfaer MA, Saatman KE. Rapid loss and partial recovery of neurofilament immunostaining following focal brain injury in mice. Experimental Neurology. 175: 198-208. PMID 12009772 DOI: 10.1006/exnr.2002.7880  1
2002 Raghupathi R, Conti AC, Graham DI, Krajewski S, Reed JC, Grady MS, Trojanowski JQ, McIntosh TK. Mild traumatic brain injury induces apoptotic cell death in the cortex that is preceded by decreases in cellular Bcl-2 immunoreactivity. Neuroscience. 110: 605-16. PMID 11934469 DOI: 10.1016/S0306-4522(01)00461-4  1
2001 Marciano P, Eberwine JH, Raghupathi R, McIntosh TK. The assessment of genomic alterations using DNA arrays following traumatic brain injury: a review. Restorative Neurology and Neuroscience. 18: 105-13. PMID 11847433  1
2001 Williams S, Raghupathi R, MacKinnon MA, McIntosh TK, Saatman KE, Graham DI. In situ DNA fragmentation occurs in white matter up to 12 months after head injury in man. Acta Neuropathologica. 102: 581-90. PMID 11761718  1
2001 Laurer HL, Bareyre FM, Lee VM, Trojanowski JQ, Longhi L, Hoover R, Saatman KE, Raghupathi R, Hoshino S, Grady MS, McIntosh TK. Mild head injury increasing the brain's vulnerability to a second concussive impact. Journal of Neurosurgery. 95: 859-70. PMID 11702878 DOI: 10.3171/jns.2001.95.5.0859  1
2001 Longhi L, Saatman KE, Raghupathi R, Laurer HL, Lenzlinger PM, Riess P, Neugebauer E, Trojanowski JQ, Lee VM, Grady MS, Graham DI, McIntosh TK. A review and rationale for the use of genetically engineered animals in the study of traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 1241-58. PMID 11702040 DOI: 10.1097/00004647-200111000-00001  1
2001 Riess P, Bareyre FM, Saatman KE, Cheney JA, Lifshitz J, Raghupathi R, Grady MS, Neugebauer E, McIntosh TK. Effects of chronic, post-injury Cyclosporin A administration on motor and sensorimotor function following severe, experimental traumatic brain injury. Restorative Neurology and Neuroscience. 18: 1-8. PMID 11673665  1
2001 Shaw K, MacKinnon MA, Raghupathi R, Saatman KE, Mclntosh TK, Graham DI. TUNEL-positive staining in white and grey matter after fatal head injury in man. Clinical Neuropathology. 20: 106-12. PMID 11430493  1
2001 Bain AC, Raghupathi R, Meaney DF. Dynamic stretch correlates to both morphological abnormalities and electrophysiological impairment in a model of traumatic axonal injury. Journal of Neurotrauma. 18: 499-511. PMID 11393253 DOI: 10.1089/089771501300227305  1
2001 LaPlaca MC, Zhang J, Raghupathi R, Li JH, Smith F, Bareyre FM, Snyder SH, Graham DI, McIntosh TK. Pharmacologic inhibition of poly(ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats. Journal of Neurotrauma. 18: 369-76. PMID 11336438 DOI: 10.1089/089771501750170912  1
2001 Cheney JA, Weisser JD, Bareyre FM, Laurer HL, Saatman KE, Raghupathi R, Gribkoff V, Starrett JE, McIntosh TK. The maxi-K channel opener BMS-204352 attenuates regional cerebral edema and neurologic motor impairment after experimental brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 396-403. PMID 11323525 DOI: 10.1097/00004647-200104000-00008  1
2001 Bareyre FM, Raghupathi R, Saatman KE, McIntosh TK. DNase I disinhibition is predominantly associated with actin hyperpolymerization after traumatic brain injury. Journal of Neurochemistry. 77: 173-81. PMID 11279273 DOI: 10.1046/j.1471-4159.2001.00215.x  1
2000 O'Dell DM, Muir JK, Zhang C, Bareyre FM, Saatman KE, Raghupathi R, Welsh F, McIntosh TK. Lubeluzole treatment does not attenuate neurobehavioral dysfunction or CA3 hippocampal neuronal loss following traumatic brain injury in rats. Restorative Neurology and Neuroscience. 16: 127-134. PMID 12671215  1
2000 Bareyre FM, Saatman KE, Raghupathi R, McIntosh TK. Postinjury treatment with magnesium chloride attenuates cortical damage after traumatic brain injury in rats. Journal of Neurotrauma. 17: 1029-39. PMID 11101206  1
2000 Durham SR, Raghupathi R, Helfaer MA, Marwaha S, Duhaime AC. Age-related differences in acute physiologic response to focal traumatic brain injury in piglets. Pediatric Neurosurgery. 33: 76-82. PMID 11070433  1
2000 Raghupathi R, Graham DI, McIntosh TK. Apoptosis after traumatic brain injury. Journal of Neurotrauma. 17: 927-38. PMID 11063058  1
2000 Smith FM, Raghupathi R, MacKinnon MA, McIntosh TK, Saatman KE, Meaney DF, Graham DI. TUNEL-positive staining of surface contusions after fatal head injury in man. Acta Neuropathologica. 100: 537-45. PMID 11045676 DOI: 10.1007/s004010000222  1
2000 Blaha GR, Raghupathi R, Saatman KE, McIntosh TK. Brain-derived neurotrophic factor administration after traumatic brain injury in the rat does not protect against behavioral or histological deficits. Neuroscience. 99: 483-93. PMID 11029540 DOI: 10.1016/S0306-4522(00)00214-1  1
2000 Strauss KI, Barbe MF, Marshall RM, Raghupathi R, Mehta S, Narayan RK. Prolonged cyclooxygenase-2 induction in neurons and glia following traumatic brain injury in the rat. Journal of Neurotrauma. 17: 695-711. PMID 10972245  1
2000 Duhaime AC, Margulies SS, Durham SR, O'Rourke MM, Golden JA, Marwaha S, Raghupathi R. Maturation-dependent response of the piglet brain to scaled cortical impact. Journal of Neurosurgery. 93: 455-62. PMID 10969944 DOI: 10.3171/jns.2000.93.3.0455  1
2000 Galvin JE, Nakamura M, McIntosh TK, Saatman KE, Sampathu D, Raghupathi R, Lee VM, Trojanowski JQ. Neurofilament-rich intraneuronal inclusions exacerbate neurodegenerative sequelae of brain trauma in NFH/LacZ transgenic mice. Experimental Neurology. 165: 77-89. PMID 10964487 DOI: 10.1006/exnr.2000.7461  1
2000 Emery DL, Raghupathi R, Saatman KE, Fischer I, Grady MS, McIntosh TK. Bilateral growth-related protein expression suggests a transient increase in regenerative potential following brain trauma. The Journal of Comparative Neurology. 424: 521-31. PMID 10906717 DOI: 10.1002/1096-9861(20000828)424:3<521::AID-CNE9>3.0.CO;2-8  1
2000 O'Dell DM, Raghupathi R, Crino PB, Eberwine JH, McIntosh TK. Traumatic brain injury alters the molecular fingerprint of TUNEL-positive cortical neurons In vivo: A single-cell analysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 4821-8. PMID 10864939  1
2000 Nakagawa Y, Reed L, Nakamura M, McIntosh TK, Smith DH, Saatman KE, Raghupathi R, Clemens J, Saido TC, Lee VM, Trojanowski JQ. Brain trauma in aged transgenic mice induces regression of established abeta deposits. Experimental Neurology. 163: 244-52. PMID 10785464 DOI: 10.1006/exnr.2000.7375  1
2000 Cheney JA, Brown AL, Bareyre FM, Russ AB, Weisser JD, Ensinger HA, Leusch A, Raghupathi R, Saatman KE. The novel compound LOE 908 attenuates acute neuromotor dysfunction but not cognitive impairment or cortical tissue loss following traumatic brain injury in rats. Journal of Neurotrauma. 17: 83-91. PMID 10674760  1
2000 Graham DI, Raghupathi R, Saatman KE, Meaney D, McIntosh TK. Tissue tears in the white matter after lateral fluid percussion brain injury in the rat: relevance to human brain injury. Acta Neuropathologica. 99: 117-24. PMID 10672317  1
1999 Kurth CD, Priestley M, Golden J, McCann J, Raghupathi R. Regional patterns of neuronal death after deep hypothermic circulatory arrest in newborn pigs. The Journal of Thoracic and Cardiovascular Surgery. 118: 1068-77. PMID 10595980  1
1999 Sanderson KL, Raghupathi R, Saatman KE, Martin D, Miller G, McIntosh TK. Interleukin-1 receptor antagonist attenuates regional neuronal cell death and cognitive dysfunction after experimental brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 1118-25. PMID 10532636 DOI: 10.1097/00004647-199910000-00008  1
1999 Muir JK, Raghupathi R, Emery DL, Bareyre FM, McIntosh TK. Postinjury magnesium treatment attenuates traumatic brain injury-induced cortical induction of p53 mRNA in rats. Experimental Neurology. 159: 584-93. PMID 10506531 DOI: 10.1006/exnr.1999.7187  1
1999 Zhang C, Raghupathi R, Saatman KE, LaPlaca MC, McIntosh TK. Regional and temporal alterations in DNA fragmentation factor (DFF)-like proteins following experimental brain trauma in the rat. Journal of Neurochemistry. 73: 1650-9. PMID 10501212 DOI: 10.1046/j.1471-4159.1999.0731650.x  1
1999 Nakamura M, Raghupathi R, Merry DE, Scherbel U, Saatman KE, Mcintosh TK. Overexpression of Bcl-2 is neuroprotective after experimental brain injury in transgenic mice. The Journal of Comparative Neurology. 412: 681-92. PMID 10464363 DOI: 10.1002/(SICI)1096-9861(19991004)412:4<681::AID-CNE9>3.0.CO;2-F  1
1999 Nakagawa Y, Nakamura M, McIntosh TK, Rodriguez A, Berlin JA, Smith DH, Saatman KE, Raghupathi R, Clemens J, Saido TC, Schmidt ML, Lee VM, Trojanowski JQ. Traumatic brain injury in young, amyloid-beta peptide overexpressing transgenic mice induces marked ipsilateral hippocampal atrophy and diminished Abeta deposition during aging. The Journal of Comparative Neurology. 411: 390-8. PMID 10413774 DOI: 10.1002/(SICI)1096-9861(19990830)411:3<390::AID-CNE3>3.0.CO;2-#  1
1999 Philips MF, Muir JK, Saatman KE, Raghupathi R, Lee VM, Trojanowski JQ, McIntosh TK. Survival and integration of transplanted postmitotic human neurons following experimental brain injury in immunocompetent rats. Journal of Neurosurgery. 90: 116-24. PMID 10413164 DOI: 10.3171/jns.1999.90.1.0116  1
1999 Nakamura M, Saatman KE, Galvin JE, Scherbel U, Raghupathi R, Trojanowski JQ, McIntosh TK. Increased vulnerability of NFH-LacZ transgenic mouse to traumatic brain injury-induced behavioral deficits and cortical damage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 762-70. PMID 10413031 DOI: 10.1097/00004647-199907000-00006  1
1999 Scherbel U, Raghupathi R, Nakamura M, Saatman KE, Trojanowski JQ, Neugebauer E, Marino MW, McIntosh TK. Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury. Proceedings of the National Academy of Sciences of the United States of America. 96: 8721-6. PMID 10411942 DOI: 10.1073/pnas.96.15.8721  1
1999 Napieralski JA, Raghupathi R, McIntosh TK. The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury. Brain Research. Molecular Brain Research. 71: 78-86. PMID 10407189 DOI: 10.1016/S0169-328X(99)00155-2  1
1999 Hill-Felberg SJ, McIntosh TK, Oliver DL, Raghupathi R, Barbarese E. Concurrent loss and proliferation of astrocytes following lateral fluid percussion brain injury in the adult rat. Journal of Neuroscience Research. 57: 271-9. PMID 10398305 DOI: 10.1002/(SICI)1097-4547(19990715)57:2<271::AID-JNR13>3.0.CO;2-Z  1
1999 LaPlaca MC, Raghupathi R, Verma A, Pieper AA, Saatman KE, Snyder SH, McIntosh TK. Temporal patterns of poly(ADP-ribose) polymerase activation in the cortex following experimental brain injury in the rat. Journal of Neurochemistry. 73: 205-13. PMID 10386972 DOI: 10.1046/j.1471-4159.1999.0730205.x  1
1999 Muir JK, Raghupathi R, Saatman KE, Wilson CA, Lee VM, Trojanowski JQ, Philips MF, McIntosh TK. Terminally differentiated human neurons survive and integrate following transplantation into the traumatically injured rat brain. Journal of Neurotrauma. 16: 403-14. PMID 10369560  1
1999 Guluma KZ, Saatman KE, Brown A, Raghupathi R, McIntosh TK. Sequential pharmacotherapy with magnesium chloride and basic fibroblast growth factor after fluid percussion brain injury results in less neuromotor efficacy than that achieved with magnesium alone. Journal of Neurotrauma. 16: 311-21. PMID 10225217  1
1999 Steward O, Schauwecker PE, Guth L, Zhang Z, Fujiki M, Inman D, Wrathall J, Kempermann G, Gage FH, Saatman KE, Raghupathi R, McIntosh T. Genetic approaches to neurotrauma research: opportunities and potential pitfalls of murine models. Experimental Neurology. 157: 19-42. PMID 10222106 DOI: 10.1006/exnr.1999.7040  1
1999 Duhaime AC, Raghupathi R. Age-specific therapy for traumatic injury of the immature brain: experimental approaches. Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft FüR Toxikologische Pathologie. 51: 172-7. PMID 10192586 DOI: 10.1016/S0940-2993(99)80091-8  1
1999 Huh J, Saatman KE, Raghupathi R, Laurer HL, Helfaer MA, McIntosh TK. Dephosphorylated neurofilaments are vulnerable following focal traumatic brain injury in mice Critical Care Medicine. 27: A59.  1
1999 Kesavulu V, Keller J, Helfaer MA, McIntosh TK, Welsh F, Raghupathi R. Hypoxic hypoxemia increases mortality and morbidity with mild experimental traumatic brain injury Critical Care Medicine. 27: A63.  1
1998 Raghupathi R, McIntosh TK. Pharmacotherapy for traumatic brain injury: a review. Proceedings of the Western Pharmacology Society. 41: 241-6. PMID 9836300  1
1998 Raghupathi R, Fernandez SC, Murai H, Trusko SP, Scott RW, Nishioka WK, McIntosh TK. BCL-2 overexpression attenuates cortical cell loss after traumatic brain injury in transgenic mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 1259-69. PMID 9809516 DOI: 10.1097/00004647-199811000-00013  1
1998 O'Dell DM, Raghupathi R, Crino PB, Morrison B, Eberwine JH, McIntosh TK. Amplification of mRNAs from single, fixed, TUNEL-positive cells. Biotechniques. 25: 566-8, 570. PMID 9793634  1
1998 McIntosh TK, Saatman KE, Raghupathi R, Graham DI, Smith DH, Lee VM, Trojanowski JQ. The Dorothy Russell Memorial Lecture. The molecular and cellular sequelae of experimental traumatic brain injury: pathogenetic mechanisms. Neuropathology and Applied Neurobiology. 24: 251-67. PMID 9775390 DOI: 10.1046/j.1365-2990.1998.00121.x  1
1998 Smith DH, Nakamura M, McIntosh TK, Wang J, Rodríguez A, Chen XH, Raghupathi R, Saatman KE, Clemens J, Schmidt ML, Lee VM, Trojanowski JQ. Brain trauma induces massive hippocampal neuron death linked to a surge in beta-amyloid levels in mice overexpressing mutant amyloid precursor protein. The American Journal of Pathology. 153: 1005-10. PMID 9736050  1
1998 Raghupathi R, Grants I, Rosenberg LJ, McIntosh TK, Lucas JH. Increased jun immunoreactivity in an in vitro model of mammalian spinal neuron physical injury. Journal of Neurotrauma. 15: 555-61. PMID 9674558  1
1998 Conti AC, Raghupathi R, Trojanowski JQ, McIntosh TK. Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5663-72. PMID 9671657  1
1998 Zhang C, Raghupathi R, Saatman KE, Smith DH, Stutzmann JM, Wahl F, McIntosh TK. Riluzole attenuates cortical lesion size, but not hippocampal neuronal loss, following traumatic brain injury in the rat. Journal of Neuroscience Research. 52: 342-9. PMID 9590442 DOI: 10.1002/(SICI)1097-4547(19980501)52:3<342::AID-JNR10>3.0.CO;2-8  1
1998 Murai H, Pierce JE, Raghupathi R, Smith DH, Saatman KE, Trojanowski JQ, Lee VM, Loring JF, Eckman C, Younkin S, McIntosh TK. Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury. The Journal of Comparative Neurology. 392: 428-38. PMID 9514508 DOI: 10.1002/(SICI)1096-9861(19980323)392:4<428::AID-CNE2>3.0.CO;2-2  1
1997 Saatman KE, Contreras PC, Smith DH, Raghupathi R, McDermott KL, Fernandez SC, Sanderson KL, Voddi M, McIntosh TK. Insulin-like growth factor-1 (IGF-1) improves both neurological motor and cognitive outcome following experimental brain injury. Experimental Neurology. 147: 418-27. PMID 9344566 DOI: 10.1006/exnr.1997.6629  1
1997 Smith DH, Perri BR, Raghupathi R, Saatman KE, McIntosh TK. Remacemide hydrochloride reduces cortical lesion volume following brain trauma in the rat. Neuroscience Letters. 231: 135-8. PMID 9300640 DOI: 10.1016/S0304-3940(97)00551-X  1
1997 McDermott KL, Raghupathi R, Fernandez SC, Saatman KE, Protter AA, Finklestein SP, Sinson G, Smith DH, McIntosh TK. Delayed administration of basic fibroblast growth factor (bFGF) attenuates cognitive dysfunction following parasagittal fluid percussion brain injury in the rat. Journal of Neurotrauma. 14: 191-200. PMID 9151768  1
1997 Perri BR, Smith DH, Murai H, Sinson G, Saatman KE, Raghupathi R, Bartus RT, McIntosh TK. Metabolic quantification of lesion volume following experimental traumatic brain injury in the rat. Journal of Neurotrauma. 14: 15-22. PMID 9048307  1
1997 Raghupathi R, McIntosh TK. Drugs in the management of acute traumatic brain injury Physical Medicine and Rehabilitation Clinics of North America. 8: 629-649.  1
1997 Mcintosh TK, Saatman KE, Raghupathi R. Calcium and the pathogenesis of traumatic CNS injury: Cellular and molecular mechanisms Neuroscientist. 3: 169-175.  1
1996 Raghupathi R, McIntosh TK. Regionally and temporally distinct patterns of induction of c-fos, c-jun and junB mRNAs following experimental brain injury in the rat. Brain Research. Molecular Brain Research. 37: 134-44. PMID 8738144 DOI: 10.1016/0169-328X(95)00289-5  1
1995 Raghupathi R, McIntosh TK, Smith DH. Cellular responses to experimental brain injury. Brain Pathology (Zurich, Switzerland). 5: 437-42. PMID 8974626  1
1995 McIntosh TK, Raghupathi R. Cell stress genes and acute CNS injury. Neuropathology and Applied Neurobiology. 21: 477-9. PMID 8745233  1
1995 Hayes RL, Yang K, Raghupathi R, McIntosh TK. Changes in gene expression following traumatic brain injury in the rat. Journal of Neurotrauma. 12: 779-90. PMID 8594207  1
1995 Raghupathi R, Welsh FA, Lowenstein DH, Gennarelli TA, McIntosh TK. Regional induction of c-fos and heat shock protein-72 mRNA following fluid-percussion brain injury in the rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 15: 467-73. PMID 7714005 DOI: 10.1038/jcbfm.1995.58  1
1994 Raghupathi RN, Diwan AM. A protocol for protein estimation that gives a nearly constant color yield with simple proteins and nullifies the effects of four known interfering agents: microestimation of peptide groups. Analytical Biochemistry. 219: 356-9. PMID 8080092 DOI: 10.1006/abio.1994.1276  1
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