Roger D. Spealman - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 

154 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Gauthier JM, Lin A, Nic Dhonnchadha BÁ, Spealman RD, Man HY, Kantak KM. Environmental enrichment facilitates cocaine-cue extinction, deters reacquisition of cocaine self-administration and alters AMPAR GluA1 expression and phosphorylation. Addiction Biology. PMID 26384129 DOI: 10.1111/adb.12313  1
2015 Rüedi-Bettschen D, Spealman RD, Platt DM. Attenuation of cocaine-induced reinstatement of drug seeking in squirrel monkeys by direct and indirect activation of 5-HT2C receptors. Psychopharmacology. 232: 2959-68. PMID 25877746 DOI: 10.1007/s00213-015-3932-z  1
2015 Hallett PJ, Deleidi M, Astradsson A, Smith GA, Cooper O, Osborn TM, Sundberg M, Moore MA, Perez-Torres E, Brownell AL, Schumacher JM, Spealman RD, Isacson O. Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson's disease. Cell Stem Cell. 16: 269-74. PMID 25732245 DOI: 10.1016/j.stem.2015.01.018  1
2013 Sundberg M, Bogetofte H, Lawson T, Jansson J, Smith G, Astradsson A, Moore M, Osborn T, Cooper O, Spealman R, Hallett P, Isacson O. Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons. Stem Cells (Dayton, Ohio). 31: 1548-62. PMID 23666606 DOI: 10.1002/stem.1415  1
2012 Achat-Mendes C, Nic Dhonnchadha BÁ, Platt DM, Kantak KM, Spealman RD. Glycine transporter-1 inhibition preceding extinction training inhibits reacquisition of cocaine seeking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2837-45. PMID 22948980 DOI: 10.1038/npp.2012.155  1
2012 Achat-Mendes C, Platt DM, Spealman RD. Antagonism of metabotropic glutamate 1 receptors attenuates behavioral effects of cocaine and methamphetamine in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 343: 214-24. PMID 22815535 DOI: 10.1124/jpet.112.196295  1
2012 Nic Dhonnchadha BÁ, Pinard E, Alberati D, Wettstein JG, Spealman RD, Kantak KM. Inhibiting glycine transporter-1 facilitates cocaine-cue extinction and attenuates reacquisition of cocaine-seeking behavior. Drug and Alcohol Dependence. 122: 119-26. PMID 21992874 DOI: 10.1016/j.drugalcdep.2011.09.017  1
2011 Platt DM, Carey G, Spealman RD. Models of neurological disease (substance abuse): self-administration in monkeys. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit10.5. PMID 22382996 DOI: 10.1002/0471141755.ph1005s56  1
2010 Xu TX, Ma Q, Spealman RD, Yao WD. Amphetamine modulation of long-term potentiation in the prefrontal cortex: dose dependency, monoaminergic contributions, and paradoxical rescue in hyperdopaminergic mutant. Journal of Neurochemistry. 115: 1643-54. PMID 20969573 DOI: 10.1111/j.1471-4159.2010.07073.x  1
2010 Achat-Mendes C, Grundt P, Cao J, Platt DM, Newman AH, Spealman RD. Dopamine D3 and D2 receptor mechanisms in the abuse-related behavioral effects of cocaine: studies with preferential antagonists in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 334: 556-65. PMID 20494958 DOI: 10.1124/jpet.110.167619  1
2010 Platt DM, Rowlett JK, Spealman RD. Asymmetric generalization and interaction profiles in rhesus monkeys discriminating intravenous cocaine or intravenous heroin from vehicle. The Journal of Pharmacology and Experimental Therapeutics. 332: 985-95. PMID 19965959 DOI: 10.1124/jpet.109.162941  1
2010 Rüedi-Bettschen D, Rowlett JK, Spealman RD, Platt DM. Attenuation of cocaine-induced reinstatement of drug seeking in squirrel monkeys: kappa opioid and serotonergic mechanisms. Psychopharmacology. 210: 169-77. PMID 19859697 DOI: 10.1007/s00213-009-1705-2  1
2010 Nic Dhonnchadha BA, Szalay JJ, Achat-Mendes C, Platt DM, Otto MW, Spealman RD, Kantak KM. D-cycloserine deters reacquisition of cocaine self-administration by augmenting extinction learning. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 357-67. PMID 19741593 DOI: 10.1038/npp.2009.139  1
2009 Xu TX, Sotnikova TD, Liang C, Zhang J, Jung JU, Spealman RD, Gainetdinov RR, Yao WD. Hyperdopaminergic tone erodes prefrontal long-term potential via a D2 receptor-operated protein phosphatase gate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14086-99. PMID 19906957 DOI: 10.1523/JNEUROSCI.0974-09.2009  1
2009 Achat-Mendes C, Platt DM, Newman AH, Spealman RD. The dopamine D3 receptor partial agonist CJB 090 inhibits the discriminative stimulus but not the reinforcing or priming effects of cocaine in squirrel monkeys. Psychopharmacology. 206: 73-84. PMID 19513698 DOI: 10.1007/s00213-009-1581-9  1
2009 Astradsson A, Jenkins BG, Choi JK, Hallett PJ, Levesque MA, McDowell JS, Brownell AL, Spealman RD, Isacson O. The blood-brain barrier is intact after levodopa-induced dyskinesias in parkinsonian primates--evidence from in vivo neuroimaging studies. Neurobiology of Disease. 35: 348-51. PMID 19501164 DOI: 10.1016/j.nbd.2009.05.018  1
2009 Achat-Mendes C, Valdez GR, Platt DM, Rowlett JK, Spealman RD. Intravenous self-administration of etonitazene alone and combined with cocaine in rhesus monkeys: comparison with heroin and antagonism by naltrexone and naloxonazine. Psychopharmacology. 204: 489-98. PMID 19225763 DOI: 10.1007/s00213-009-1480-0  1
2008 Platt DM, Rowlett JK, Spealman RD. Attenuation of cocaine self-administration in squirrel monkeys following repeated administration of the mGluR5 antagonist MPEP: comparison with dizocilpine. Psychopharmacology. 200: 167-76. PMID 18509621 DOI: 10.1007/s00213-008-1191-y  1
2008 Yao WD, Spealman RD, Zhang J. Dopaminergic signaling in dendritic spines. Biochemical Pharmacology. 75: 2055-69. PMID 18353279 DOI: 10.1016/j.bcp.2008.01.018  1
2008 Haney M, Spealman R. Controversies in translational research: drug self-administration. Psychopharmacology. 199: 403-19. PMID 18283437 DOI: 10.1007/s00213-008-1079-x  1
2008 Rocha BA, Bergman J, Comer SD, Haney M, Spealman RD. Development of medications for heroin and cocaine addiction and regulatory aspects of abuse liability testing Animal and Translational Models For Cns Drug Discovery. 3: 221-270. DOI: 10.1016/B978-0-12-373861-5.00027-8  1
2007 Valdez GR, Platt DM, Rowlett JK, Rüedi-Bettschen D, Spealman RD. Kappa agonist-induced reinstatement of cocaine seeking in squirrel monkeys: a role for opioid and stress-related mechanisms. The Journal of Pharmacology and Experimental Therapeutics. 323: 525-33. PMID 17702903 DOI: 10.1124/jpet.107.125484  1
2007 Platt DM, Rowlett JK, Spealman RD. Noradrenergic mechanisms in cocaine-induced reinstatement of drug seeking in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 322: 894-902. PMID 17505018 DOI: 10.1124/jpet.107.121806  1
2007 Rowlett JK, Platt DM, Yao WD, Spealman RD. Modulation of heroin and cocaine self-administration by dopamine D1- and D2-like receptor agonists in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 321: 1135-43. PMID 17351103 DOI: 10.1124/jpet.107.120766  1
2006 Adewale AS, Platt DM, Spealman RD. Pharmacological stimulation of group ii metabotropic glutamate receptors reduces cocaine self-administration and cocaine-induced reinstatement of drug seeking in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 318: 922-31. PMID 16675638 DOI: 10.1124/jpet.106.105387  1
2005 Platt DM, Carey G, Spealman RD. Intravenous self-administration techniques in monkeys. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 9.21. PMID 18428630 DOI: 10.1002/0471142301.ns0921s32  1
2005 Platt DM, Duggan A, Spealman RD, Cook JM, Li X, Yin W, Rowlett JK. Contribution of alpha 1GABAA and alpha 5GABAA receptor subtypes to the discriminative stimulus effects of ethanol in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 313: 658-67. PMID 15650112 DOI: 10.1124/jpet.104.080275  1
2005 Rowlett JK, Rodefer JS, Spealman RD. Self-Administration of cocaine-opioid combinations by rhesus monkeys: evaluation of the role of mu receptor efficacy using labor supply analysis. The Journal of Pharmacology and Experimental Therapeutics. 312: 1289-97. PMID 15550572 DOI: 10.1124/jpet.104.076646  1
2005 Lee B, Platt DM, Rowlett JK, Adewale AS, Spealman RD. Attenuation of behavioral effects of cocaine by the Metabotropic Glutamate Receptor 5 Antagonist 2-Methyl-6-(phenylethynyl)-pyridine in squirrel monkeys: comparison with dizocilpine. The Journal of Pharmacology and Experimental Therapeutics. 312: 1232-40. PMID 15550570 DOI: 10.1124/jpet.104.078733  1
2004 Spealman RD, Lee B, Tiefenbacher S, Platt DM, Rowlett JK, Khroyan TV. Triggers of relapse: nonhuman primate models of reinstated cocaine seeking. Nebraska Symposium On Motivation. Nebraska Symposium On Motivation. 50: 57-84. PMID 15160638  1
2004 Rowlett JK, Platt DM, Spealman RD. Cocaine-like discriminative stimulus effects of heroin: modulation by selective monoamine transport inhibitors. The Journal of Pharmacology and Experimental Therapeutics. 310: 342-8. PMID 14985417 DOI: 10.1124/jpet.104.065631  1
2004 Lee B, Tiefenbacher S, Platt DM, Spealman RD. Pharmacological blockade of alpha2-adrenoceptors induces reinstatement of cocaine-seeking behavior in squirrel monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 686-93. PMID 14872205 DOI: 10.1038/sj.npp.1300391  1
2004 Platt DM, Rowlett JK, Izenwasser S, Spealman RD. Opioid partial agonist effects of 3-O-methylnaltrexone in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 308: 1030-9. PMID 14634035 DOI: 10.1124/jpet.103.060962  1
2003 Madras BK, Fahey MA, Miller GM, De La Garza R, Goulet M, Spealman RD, Meltzer PC, George SR, O'Dowd BF, Bonab AA, Livni E, Fischman AJ. Non-amine-based dopamine transporter (reuptake) inhibitors retain properties of amine-based progenitors. European Journal of Pharmacology. 479: 41-51. PMID 14612136 DOI: 10.1016/j.ejphar.2003.08.055  1
2003 Tiefenbacher S, Lee B, Meyer JS, Spealman RD. Noninvasive technique for the repeated sampling of salivary free cortisol in awake, unrestrained squirrel monkeys. American Journal of Primatology. 60: 69-75. PMID 12784287 DOI: 10.1002/ajp.10080  1
2003 Lee B, Tiefenbacher S, Platt DM, Spealman RD. Role of the hypothalamic-pituitary-adrenal axis in reinstatement of cocaine-seeking behavior in squirrel monkeys. Psychopharmacology. 168: 177-83. PMID 12652344 DOI: 10.1007/s00213-003-1391-4  1
2003 Khroyan TV, Platt DM, Rowlett JK, Spealman RD. Attenuation of relapse to cocaine seeking by dopamine D1 receptor agonists and antagonists in non-human primates. Psychopharmacology. 168: 124-31. PMID 12607074 DOI: 10.1007/s00213-002-1365-y  1
2003 Platt DM, Rodefer JS, Rowlett JK, Spealman RD. Suppression of cocaine- and food-maintained behavior by the D2-like receptor partial agonist terguride in squirrel monkeys. Psychopharmacology. 166: 298-305. PMID 12589523 DOI: 10.1007/s00213-002-1347-0  1
2003 Rowlett JK, Spealman RD, Lelas S, Cook JM, Yin W. Discriminative stimulus effects of zolpidem in squirrel monkeys: role of GABA(A)/alpha1 receptors. Psychopharmacology. 165: 209-15. PMID 12420154 DOI: 10.1007/s00213-002-1275-z  1
2002 Rowlett JK, Rodefer JS, Spealman RD. Self-administration of cocaine, alfentanil, and nalbuphine under progressive-ratio schedules: consumer demand and labor supply analyses of relative reinforcing effectiveness. Experimental and Clinical Psychopharmacology. 10: 367-75. PMID 12498333 DOI: 10.1037//1064-1297.10.4.367  1
2002 Platt DM, Rowlett JK, Spealman RD, Cook J, Ma C. Selective antagonism of the ataxic effects of zolpidem and triazolam by the GABAA/alpha1-preferring antagonist beta-CCt in squirrel monkeys. Psychopharmacology. 164: 151-9. PMID 12404077 DOI: 10.1007/s00213-002-1189-9  1
2002 Platt DM, Rowlett JK, Spealman RD. Behavioral effects of cocaine and dopaminergic strategies for preclinical medication development. Psychopharmacology. 163: 265-82. PMID 12373428 DOI: 10.1007/s00213-002-1137-8  1
2002 Lelas S, Rowlett JK, Spealman RD, Cook JM, Ma C, Li X, Yin W. Role of GABAA/benzodiazepine receptors containing alpha 1 and alpha 5 subunits in the discriminative stimulus effects of triazolam in squirrel monkeys. Psychopharmacology. 161: 180-8. PMID 11981598 DOI: 10.1007/s00213-002-1037-y  1
2002 Park WK, Bari AA, Jey AR, Anderson SM, Spealman RD, Rowlett JK, Pierce RC. Cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing AMPA receptor-mediated glutamate transmission in the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2916-25. PMID 11923456  1
2001 Lelas S, Rowlett JK, Spealman RD. Isobolographic analysis of chlordiazepoxide and triazolam combinations in squirrel monkeys discriminating triazolam. Psychopharmacology. 158: 181-9. PMID 11702092 DOI: 10.1007/s002130100868  1
2001 Rowlett JK, Spealman RD, Platt DM. Similar enhancement of the discriminative stimulus effects of cocaine and GBR 12909 by heroin in squirrel monkeys. Psychopharmacology. 157: 313-9. PMID 11605088 DOI: 10.1007/s002130100797  1
2001 Platt DM, Rowlett JK, Spealman RD. Colitis-induced alterations in adrenergic control of circular smooth muscle in vitro in rats Journal of Pharmacology and Experimental Therapeutics. 299: 768-774. PMID 11602693  1
2001 Platt DM, Rowlett JK, Spealman RD. Discriminative stimulus effects of intravenous heroin and its metabolites in rhesus monkeys: opioid and dopaminergic mechanisms. The Journal of Pharmacology and Experimental Therapeutics. 299: 760-7. PMID 11602692  0.56
2001 Platt DM, Rowlett JK, Spealman RD. Modulation of cocaine and food self-administration by low- and high-efficacy D1 agonists in squirrel monkeys. Psychopharmacology. 157: 208-16. PMID 11594448 DOI: 10.1007/s002130100779  1
2001 Lelas S, Rowlett JK, Spealman RD. Triazolam discrimination in squirrel monkeys distinguishes high-efficacy agonists from other benzodiazepines and non-benzodiazepine drugs. Psychopharmacology. 154: 96-104. PMID 11292012 DOI: 10.1007/s002130000615  1
2000 Rowlett JK, Lelas S, Spealman RD. Transduction of the discriminative stimulus effects of zolpidem by GABA(A)/alpha1 receptors. European Journal of Pharmacology. 406: R9-R10. PMID 11011051 DOI: 10.1016/S0014-2999(00)00669-5  1
2000 Lelas S, Spealman RD, Rowlett JK. Using behavior to elucidate receptor mechanisms: a review of the discriminative stimulus effects of benzodiazepines. Experimental and Clinical Psychopharmacology. 8: 294-311. PMID 10975618 DOI: 10.1037//1064-1297.8.3.294  1
2000 Spealman RD, Khroyan TV, Barrett-Larimore RL, Rowlett JK, Platt DM. Dopaminergic mechanisms in relapse to cocaine-seeking behavior. Implications for medications development. Annals of the New York Academy of Sciences. 909: 273-4. PMID 10911940  1
2000 Rowlett JK, Spealman RD, Platt DM. Cocaine-like discriminative stimulus effects of heroin in squirrel monkeys: role of active metabolites and opioid receptor mechanisms. Psychopharmacology. 150: 191-9. PMID 10907672 DOI: 10.1007/s002130000427  1
2000 Khroyan TV, Barrett-Larimore RL, Rowlett JK, Spealman RD. Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine-seeking behavior: effects of selective antagonists and agonists. The Journal of Pharmacology and Experimental Therapeutics. 294: 680-7. PMID 10900248  1
2000 Platt DM, Rowlett JK, Spealman RD. Dissociation of cocaine-antagonist properties and motoric effects of the D1 receptor partial agonists SKF 83959 and SKF 77434. The Journal of Pharmacology and Experimental Therapeutics. 293: 1017-26. PMID 10869406  1
1999 Kantak KM, Riberdy A, Spealman RD. Cocaine-opioid interactions in groups of rats trained to discriminate different doses of cocaine. Psychopharmacology. 147: 257-65. PMID 10639683 DOI: 10.1007/s002130051165  1
1999 Rowlett JK, Spealman RD, Lelas S. Discriminative stimulus effects of zolpidem in squirrel monkeys: comparison with conventional benzodiazepines and sedative-hypnotics. The Journal of Pharmacology and Experimental Therapeutics. 291: 1233-41. PMID 10565847  1
1999 Spealman RD, Barrett-Larimore RL, Rowlett JK, Platt DM, Khroyan TV. Pharmacological and environmental determinants of relapse to cocaine-seeking behavior. Pharmacology, Biochemistry, and Behavior. 64: 327-36. PMID 10515309 DOI: 10.1016/S0091-3057(99)00049-0  1
1999 Platt DM, Grech DM, Rowlett JK, Spealman RD. Discriminative stimulus effects of morphine in squirrel monkeys: stimulants, opioids, and stimulant-opioid combinations. The Journal of Pharmacology and Experimental Therapeutics. 290: 1092-100. PMID 10454482  1
1998 Rowlett JK, Spealman RD. Opioid enhancement of the discriminative stimulus effects of cocaine: evidence for involvement of mu and delta opioid receptors. Psychopharmacology. 140: 217-24. PMID 9860113 DOI: 10.1007/s002130050760  1
1998 Brownell AL, Jenkins BG, Elmaleh DR, Deacon TW, Spealman RD, Isacson O. Combined PET/MRS brain studies show dynamic and long-term physiological changes in a primate model of Parkinson disease. Nature Medicine. 4: 1308-12. PMID 9809556 DOI: 10.1038/3300  1
1997 Spealman RD, Bergman J, Rosenzweig-Lipson S. Differential modulation of behavioral effects of cocaine by low- and high-efficacy D1 agonists. Psychopharmacology. 133: 283-92. PMID 9361335 DOI: 10.1007/s002130050403  1
1997 Howell LL, Coffin VL, Spealman RD. Behavioral and physiological effects of xanthines in nonhuman primates. Psychopharmacology. 129: 1-14. PMID 9122357 DOI: 10.1007/s002130050155  1
1996 Spealman RD. Dopamine D3 receptor agonists partially reproduce the discriminative stimulus effects of cocaine in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 278: 1128-37. PMID 8819495  1
1996 Bergman J, Spealman RD, Madras BK, Rosenzweig-Lipson S. Agonist efficacy and the behavioral effects of dopamine D1 receptor ligands: drug interaction studies in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 276: 942-50. PMID 8786574  1
1996 Grech DM, Spealman RD, Bergman J. Self-administration of D1 receptor agonists by squirrel monkeys. Psychopharmacology. 125: 97-104. PMID 8783382 DOI: 10.1007/BF02249407  1
1995 Bergman J, Rosenzweig-Lipson S, Spealman RD. Differential effects of dopamine D1 and D2 receptor agonists on schedule-controlled behavior of squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 273: 40-8. PMID 7714795  1
1995 Spealman RD. Discriminative stimulus effects of cocaine in squirrel monkeys: lack of antagonism by the dopamine D2 partial agonists terguride, SDZ 208-911, and SDZ 208-912. Pharmacology, Biochemistry, and Behavior. 51: 661-5. PMID 7675840 DOI: 10.1016/0091-3057(94)00434-K  1
1995 Kantak KM, Edwards MA, Spealman RD. Effects of N-methyl-D-aspartate antagonists in rats discriminating different doses of cocaine: comparison with direct and indirect dopamine agonists. The Journal of Pharmacology and Experimental Therapeutics. 274: 657-65. PMID 7636725  1
1995 Spealman RD. Noradrenergic involvement in the discriminative stimulus effects of cocaine in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 275: 53-62. PMID 7562595  1
1994 Wüllner U, Pakzaban P, Brownell AL, Hantraye P, Burns L, Shoup T, Elmaleh D, Petto AJ, Spealman RD, Brownell GL. Dopamine terminal loss and onset of motor symptoms in MPTP-treated monkeys: a positron emission tomography study with 11C-CFT. Experimental Neurology. 126: 305-9. PMID 7925829 DOI: 10.1006/exnr.1994.1069  1
1994 Spealman RD, Bergman J. Opioid modulation of the discriminative stimulus effects of cocaine: Comparison of μ, κ and δ agonists in squirrel monkeys discriminating low doses of cocaine Behavioural Pharmacology. 5: 21-31.  1
1993 Spealman RD. Modification of behavioral effects of cocaine by selective serotonin and dopamine uptake inhibitors in squirrel monkeys. Psychopharmacology. 112: 93-9. PMID 7871015 DOI: 10.1007/BF02247368  1
1993 Kantak KM, Spealman RD. Effects of magnesium chloride in rats and squirrel monkeys trained to discriminate different doses of cocaine Nida Research Monograph Series. 254.  1
1993 Bergman J, Hesterberg P, Spealman RD. Modification of the behavioral effects of cocaine by opioids in squirrel monkeys Nida Research Monograph Series. 235.  1
1992 Hantraye P, Brownell AL, Elmaleh D, Spealman RD, Wüllner U, Brownell GL, Madras BK, Isacson O. Dopamine fiber detection by [11C]-CFT and PET in a primate model of parkinsonism. Neuroreport. 3: 265-8. PMID 1515582  1
1992 Spealman RD. Failure of cholecystokinin antagonists to modify the discriminative stimulus effects of cocaine. Pharmacology, Biochemistry, and Behavior. 43: 613-6. PMID 1438498 DOI: 10.1016/0091-3057(92)90199-P  1
1992 Spealman RD. Use of cocaine-discrimination techniques for preclinical evaluation of candidate therapeutics for cocaine dependence. Nida Research Monograph. 119: 175-9. PMID 1435975  1
1992 Rosenzweig-Lipson S, Bergman J, Spealman RD, Madras BK. Stereoselective behavioral effects of Lu 19-005 in monkeys: relation to binding at cocaine recognition sites. Psychopharmacology. 107: 186-94. PMID 1377395 DOI: 10.1007/BF02245136  1
1992 Spealman RD, Bergman J, Madras BK, Kamien JB, Melia KF. Role of D1 and D2 dopamine receptors in the behavioral effects of cocaine. Neurochemistry International. 20: 147S-152S. PMID 1365414 DOI: 10.1016/0197-0186(92)90228-J  1
1992 Spealman RD, Bergman J. Modulation of the discriminative stimulus effects of cocaine by mu and kappa opioids. The Journal of Pharmacology and Experimental Therapeutics. 261: 607-15. PMID 1315861  1
1991 Bergman J, Madras BK, Spealman RD. Behavioral effects of D1 and D2 dopamine receptor antagonists in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 258: 910-7. PMID 1890625  1
1991 Kaufman MJ, Spealman RD, Madras BK. Distribution of cocaine recognition sites in monkey brain: I. In vitro autoradiography with [3H]CFT. Synapse (New York, N.Y.). 9: 177-87. PMID 1776130 DOI: 10.1002/syn.890090304  1
1991 Spealman RD, Bergman J, Madras BK. Self-administration of the high-affinity cocaine analog 2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane. Pharmacology, Biochemistry, and Behavior. 39: 1011-3. PMID 1763097 DOI: 10.1016/0091-3057(91)90067-C  1
1991 Spealman RD, Bergman J, Madras BK, Melia KF. Discriminative stimulus effects of cocaine in squirrel monkeys: involvement of dopamine receptor subtypes. The Journal of Pharmacology and Experimental Therapeutics. 258: 945-53. PMID 1679852  1
1991 Melia KF, Spealman RD. Pharmacological characterization of the discriminative-stimulus effects of GBR 12909. The Journal of Pharmacology and Experimental Therapeutics. 258: 626-32. PMID 1678014  1
1990 Howell LL, Morse WH, Spealman RD. Respiratory effects of xanthines and adenosine analogs in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 254: 786-91. PMID 2395111  1
1990 Madras BK, Kamien JB, Fahey MA, Canfield DR, Milius RA, Saha JK, Neumeyer JL, Spealman RD. N-modified fluorophenyltropane analogs of cocaine with high affinity for cocaine receptors. Pharmacology, Biochemistry, and Behavior. 35: 949-53. PMID 2345768 DOI: 10.1016/0091-3057(90)90384-T  1
1990 Canfield DR, Spealman RD, Kaufman MJ, Madras BK. Autoradiographic localization of cocaine binding sites by [3H]CFT ([3H]WIN 35,428) in the monkey brain. Synapse (New York, N.Y.). 6: 189-95. PMID 2237780 DOI: 10.1002/syn.890060211  1
1990 Spealman RD. Antagonism of behavioral effects of cocaine by selective dopamine receptor blockers. Psychopharmacology. 101: 142-5. PMID 1971446 DOI: 10.1007/BF02253732  1
1989 Madras BK, Spealman RD, Fahey MA, Neumeyer JL, Saha JK, Milius RA. Cocaine receptors labeled by [3H]2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane. Molecular Pharmacology. 36: 518-24. PMID 2811854  1
1989 Spealman RD, Madras BK, Bergman J. Effects of cocaine and related drugs in nonhuman primates. II. Stimulant effects on schedule-controlled behavior. The Journal of Pharmacology and Experimental Therapeutics. 251: 142-9. PMID 2795456  1
1989 Bergman J, Madras BK, Johnson SE, Spealman RD. Effects of cocaine and related drugs in nonhuman primates. III. Self-administration by squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 251: 150-5. PMID 2529365  1
1989 Madras BK, Fahey MA, Bergman J, Canfield DR, Spealman RD. Effects of cocaine and related drugs in nonhuman primates. I. [3H]cocaine binding sites in caudate-putamen. The Journal of Pharmacology and Experimental Therapeutics. 251: 131-41. PMID 2529364  1
1989 Coffin VL, Spealman RD. Psychomotor-stimulant effects of 3-isobutyl-1-methylxanthine: comparison with caffeine and 7-(2-chloroethyl) theophylline. European Journal of Pharmacology. 170: 35-40. PMID 2482186 DOI: 10.1016/0014-2999(89)90130-1  1
1988 Spealman RD, Coffin VL. Discriminative-stimulus effects of adenosine analogs: mediation by adenosine A2 receptors. The Journal of Pharmacology and Experimental Therapeutics. 246: 610-8. PMID 3404449  1
1988 Kirby DA, Spealman RD. Attenuation by naloxone of the pressor effects of angiotensin II in conscious cynomolgus monkeys. Life Sciences. 43: 453-8. PMID 3398708 DOI: 10.1016/0024-3205(88)90525-5  1
1988 Wettstein JG, Spealman RD. Distinctive behavioral effects of the pyrazoloquinoline CGS 8216 in squirrel monkeys. Pharmacology, Biochemistry, and Behavior. 29: 741-5. PMID 3137587 DOI: 10.1016/0091-3057(88)90196-7  1
1988 Spealman RD. Psychomotor stimulant effects of methylxanthines in squirrel monkeys: relation to adenosine antagonism. Psychopharmacology. 95: 19-24. PMID 3133696 DOI: 10.1007/BF00212759  1
1988 Madras BK, Fahey MA, Canfield DR, Spealman RD. D1 and D2 dopamine receptors in caudate-putamen of nonhuman primates (Macaca fascicularis). Journal of Neurochemistry. 51: 934-43. PMID 2970527  1
1988 Bergman J, Spealman RD. Behavioral effects of histamine H1 antagonists: comparison with other drugs and modification by haloperidol. The Journal of Pharmacology and Experimental Therapeutics. 245: 471-8. PMID 2896793  1
1988 Wettstein JG, Spealman RD. GABA-related drugs modulate the behavioral effects of lorazepam. Psychopharmacology. 95: 38-42. PMID 2838859 DOI: 10.1007/BF00212763  1
1987 Coffin VL, Spealman RD. Behavioral and cardiovascular effects of analogs of adenosine in cynomolgus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 241: 76-83. PMID 3572798  1
1987 Wettstein JG, Spealman RD. Behavioral effects of the pyrazoloquinoline CGS 9896: agonist and antagonist actions in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 240: 82-7. PMID 3100774  1
1987 Wettstein JG, Spealman RD. Behavioral effects of the beta-carboline derivatives ZK 93423 and ZK 91296 in squirrel monkeys: comparison with lorazepam and suriclone. The Journal of Pharmacology and Experimental Therapeutics. 240: 471-5. PMID 2879907  1
1986 Spealman RD, Coffin VL. Behavioral effects of adenosine analogs in squirrel monkeys: relation to adenosine A2 receptors. Psychopharmacology. 90: 419-21. PMID 3097732 DOI: 10.1007/BF00179203  1
1986 Bergman J, Spealman RD. Some behavioral effects of histamine H1 antagonists in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 239: 104-10. PMID 2876090  1
1986 Wettstein JG, Spealman RD. Behavioral effects of zopiclone, CL 218,872 and diazepam in squirrel monkeys: antagonism by Ro 15-1788 and CGS 8216. The Journal of Pharmacology and Experimental Therapeutics. 238: 522-8. PMID 2874212  1
1986 Spealman RD. Disruption of schedule-controlled behavior by Ro 15-1788 one day after acute treatment with benzodiazepines. Psychopharmacology. 88: 398-400. PMID 2870534 DOI: 10.1007/BF00180845  1
1985 Katz JL, Spealman RD, Clark RD. Stereoselective behavioral effects of N-allylnormetazocine in pigeons and squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 232: 452-61. PMID 3968644  1
1985 Spealman RD. Discriminative-stimulus effects of midazolam in squirrel monkeys: comparison with other drugs and antagonism by Ro 15-1788. The Journal of Pharmacology and Experimental Therapeutics. 235: 456-62. PMID 2932547  1
1985 Spealman RD. Effects of some dibenzo-azepines on suppressed and nonsuppressed behavior of squirrel monkeys. Psychopharmacology. 85: 129-32. PMID 2861615 DOI: 10.1007/BF00428400  1
1985 Coffin VL, Spealman RD. Modulation of the behavioral effects of chlordiazepoxide by methylxanthines and analogs of adenosine in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 235: 724-8. PMID 2416907  1
1985 Warren PH, Spealman RD. Tolerance to the behavioral effects of phencyclidine: Cross-tolerance to ketamine and supersensitivity to morphine Federation Proceedings. 44: No. 6194.  1
1985 Wettstein JG, Spealman RD. Behavioral effects of benzodiazepine (BZ) agonist and antagonist combinations in squirrel monkeys Federation Proceedings. 44: No. 2775.  1
1985 Coffin VL, Spealman RD. Behavioral and cardiovascular effects of some adenosine analogs in cynomolgus monkeys Federation Proceedings. 44: No. 1827.  1
1984 Glowa JR, Spealman RD. Behavioral effects of caffeine, N6-(L-phenylisopropyl) adenosine and their combination in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 231: 665-70. PMID 6502521  1
1984 Bergman J, Spealman RD. Reinforcing and rate-increasing effects of histamine H1 antagonists Federation Proceedings. 43: no. 4395.  1
1983 Spealman RD, Kelleher RT, Goldberg SR. Stereoselective behavioral effects of cocaine and a phenyltropane analog. The Journal of Pharmacology and Experimental Therapeutics. 225: 509-14. PMID 6864516  1
1983 Spealman RD, Kelleher RT, Goldberg SR, DeWeese J, Goldberg DM. Behavioral effects of clozapine: comparison with thioridazine, chlorpromazine, haloperidol and chlordiazepoxide in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 224: 127-34. PMID 6848739  1
1983 Goldberg SR, Spealman RD. Suppression of behavior by intravenous injections of nicotine or by electric shocks in squirrel monkeys: effects of chlordiazepoxide and mecamylamine. The Journal of Pharmacology and Experimental Therapeutics. 224: 334-40. PMID 6822959  1
1983 Spealman RD. Maintenance of behavior by postponement of scheduled injections of nicotine in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 227: 154-9. PMID 6684684  1
1983 Goldberg SR, Spealman RD, Risner ME, Henningfield JE. Control of behavior by intravenous nicotine injections in laboratory animals. Pharmacology, Biochemistry, and Behavior. 19: 1011-20. PMID 6657719 DOI: 10.1016/0091-3057(83)90408-2  1
1983 Kirby DA, Spealman RD. Attenuation by naloxone of blood pressure responses to angiotensin II in Macaca fascicularis Federation Proceedings. 42: No. 2082.  1
1982 Spealman RD, Goldberg SR. Maintenance of schedule-controlled behavior by intravenous injections of nicotine in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 223: 402-8. PMID 7131295  1
1982 Goldberg SR, Spealman RD. Maintenance and suppression of behavior by intravenous nicotine injections in squirrel monkeys. Federation Proceedings. 41: 216-20. PMID 7060749  1
1982 McGivney WT, Spealman RD, Kelleher RT. N-allyl-N-normetazocine antagonizes effects of morphine on schedule-controlled behavior Federation Proceedings. 41: No. 4683.  1
1981 Goldberg SR, Spealman RD, Goldberg DM. Persistent behavior at high rates maintained by intravenous self-administration of nicotine. Science (New York, N.Y.). 214: 573-5. PMID 7291998  1
1981 Spealman RD, Kelleher RT, Morse WH, Goldberg SR. Supersensitivity to the behavioral effects of opiate antagonists [proceedings]. Psychopharmacology Bulletin. 17: 54-6. PMID 7232659  1
1981 Spealman RD, Kelleher RT. Self-administration of cocaine derivatives by squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 216: 532-6. PMID 7205634  1
1981 Spealman RD, Goldberg SR, Gardner ML. Behavioral effects of nicotine: schedule-controlled responding by squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 216: 484-91. PMID 7205628  1
1981 Gardner ML, Morse WH, Spealman RD, Kelleher RT. Behaviour effects of naltrexone and morphine before and after chronic administration of naltrexone in squirrel monkeys Federation Proceedings. 40: 169.  1
1981 Goldberg SR, Spealman RD, Goldberg DM. High rates of responding maintained by intravenous nicotine injections under a second-order schedule Federation Proceedings. 40: 360.  1
1980 Spealman RD, Katz JL. Some effects of clozapine on punished responding by mice and squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 212: 435-40. PMID 6767017  1
1979 Goldberg SR, Spealman RD, Kelleher RT. Enhancement of drug-seeking behavior by environmental stimuli associated with cocaine or morphine injections. Neuropharmacology. 18: 1015-7. PMID 119167 DOI: 10.1016/0028-3908(79)90169-2  1
1979 Spealman RD, Kelleher RT. Behavioral effects of self-administered cocaine: responding maintained alternately by cocaine and electric shock in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 210: 206-14. PMID 110922  1
1979 Spealman RD, Goldberg SR, Kelleher RT, Morse WH, Goldberg DM, Hakansson CG, Nieforth KA, Lazer ES. Effects of norcocaine and some norcocaine derivatives on schedule-controlled behavior of pigeons and squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 210: 196-205. PMID 110921  1
1979 Spealman RD. Behavior maintained by termination of a schedule of self-administered cocaine. Science (New York, N.Y.). 204: 1231-3. PMID 109920  1
1979 Spealman RD. Comparison of drug effects on responding punished by pressurized air or electric shock delivery in squirrel monkeys: pentobarbital, chlordiazepoxide, d-amphetamine and cocaine. The Journal of Pharmacology and Experimental Therapeutics. 209: 309-15. PMID 108387  1
1979 Spealman RD, Kelleher RT, Goldberg DM. Supersensitivity to the behavioral effects of naloxone and naltrexone after chronic administration in rhesus monkeys, squirrel monkeys and rats Federation Proceedings. 38: No. 2706.  1
1978 Spealman RD. Interactions in multiple schedules: negative induction with squirrel monkeys. Journal of the Experimental Analysis of Behavior. 30: 315-27. PMID 16812112  1
1978 Barrett JE, Spealman RD. Behavior simultaneously maintained by both presentation and termination of noxious stimuli. Journal of the Experimental Analysis of Behavior. 29: 375-83. PMID 16812064  0.96
1978 Spealman RD. Pressurized air as a punisher. Journal of the Experimental Analysis of Behavior. 29: 341-5. PMID 16812061  1
1978 Spealman RD, Katz JL, Witkin JM. Drug effects on responding maintained by stimulus-reinforcer and response-reinforcer contingencies. Journal of the Experimental Analysis of Behavior. 30: 187-96. PMID 702026 DOI: 10.1901/jeab.1978.30-187  1
1978 Spealman RD, Goldberg SR. Drug self-administration by laboratory animals: control by schedules of reinforcement. Annual Review of Pharmacology and Toxicology. 18: 313-39. PMID 348062 DOI: 10.1146/annurev.pa.18.040178.001525  1
1978 Lazer ES, Aggarwal ND, Hite GJ, Nieforth KA, Kelleher RT, Spealman RD, Schuster CR, Wolverton W. Synthesis and biological activity of cocaine analogs I: N-alkylated norcocaine derivatives. Journal of Pharmaceutical Sciences. 67: 1656-8. PMID 102759  1
1978 Goldberg SR, Spealman RD. Control of extended sequences of drug-seeking behavior by environmental stimuli Experimental Brain Research. 32: R16.  1
1978 Spealman RD, Goldberg SR, Kelleher RT. Effects of norcocaine and a norcocaine analog on schedule-controlled behavior of squirrel monkeys Federation Proceedings. 37: No.334.  1
1977 Spealman RD, Goldberg SR, Kelleher RT, Goldberg DM, Charlton JP. Some effects of cocaine and two cocaine analogs on schedule-controlled behavior of squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 202: 500-9. PMID 408481  1
1976 Spealman RD, Goldberg SR, Kelleher RT. Behavioral effects of cocaine and two cocaine analogs in squirrel monkeys Pharmacologist. 18: No.466.  1
1976 Spealman RD. Interactions im multiple schedules: the role of the stimulus reinforcer contingency Journal of the Experimental Analysis of Behavior. 26: 79-93.  1
1974 Spealman RD, Gollub LR. Behavioral interactions in multiple variable-interval schedules. Journal of the Experimental Analysis of Behavior. 22: 471-81. PMID 16811810  1
1974 Spealman RD, Gollub LR. Behavioral interactions in multiple variable interval schedules Journal of the Experimental Analysis of Behavior. 22: 471-481.  1
Show low-probability matches.