Dorothy Hanck - Publications

Affiliations: 
Neurobiology University of Chicago, Chicago, IL 
Area:
Neuroscience Biology

80 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Sheets MF, Fozzard HA, Hanck DA. Important Role of Asparagines in Coupling the Pore and Votage-Sensor Domain in Voltage-Gated Sodium Channels. Biophysical Journal. 109: 2277-86. PMID 26636939 DOI: 10.1016/j.bpj.2015.10.012  1
2013 Sheets MF, Chen T, Hanck DA. Outward stabilization of the voltage sensor in domain II but not domain I speeds inactivation of voltage-gated sodium channels. American Journal of Physiology. Heart and Circulatory Physiology. 305: H1213-21. PMID 23893162 DOI: 10.1152/ajpheart.00225.2013  1
2011 Fozzard HA, Sheets MF, Hanck DA. The sodium channel as a target for local anesthetic drugs. Frontiers in Pharmacology. 2: 68. PMID 22053156 DOI: 10.3389/fphar.2011.00068  1
2011 Lipkind GM, Fozzard HA, Hanck DA. A molecular model of the inner pore of the Ca channel in its open state. Channels (Austin, Tex.). 5: 482-8. PMID 22020562 DOI: 10.4161/chan.5.6.18354  1
2011 Li D, Herrera S, Bubula N, Nikitina E, Palmer AA, Hanck DA, Loweth JA, Vezina P. Casein kinase 1 enables nucleus accumbens amphetamine-induced locomotion by regulating AMPA receptor phosphorylation. Journal of Neurochemistry. 118: 237-47. PMID 21564097 DOI: 10.1111/J.1471-4159.2011.07308.X  1
2011 Bergson P, Lipkind G, Lee SP, Duban ME, Hanck DA. Verapamil block of T-type calcium channels. Molecular Pharmacology. 79: 411-9. PMID 21149638 DOI: 10.1124/mol.110.069492  1
2011 Sheets MF, Chen T, Hanck DA. Lidocaine partially depolarizes the S4 segment in domain IV of the sodium channel. PflüGers Archiv : European Journal of Physiology. 461: 91-7. PMID 20981437 DOI: 10.1007/s00424-010-0894-1  1
2010 Fozzard H, Hanck D. In memoriam. Morton Arnsdorf: 1940-2010. Circulation Research. 107: 446-7. PMID 20839390 DOI: 10.1161/Circresaha.110.227967  1
2010 Sheets MF, Fozzard HA, Lipkind GM, Hanck DA. Sodium channel molecular conformations and antiarrhythmic drug affinity. Trends in Cardiovascular Medicine. 20: 16-21. PMID 20685573 DOI: 10.1016/j.tcm.2010.03.002  1
2010 Edgerton GB, Blumenthal KM, Hanck DA. Inhibition of the activation pathway of the T-type calcium channel Ca(V)3.1 by ProTxII. Toxicon : Official Journal of the International Society On Toxinology. 56: 624-36. PMID 20600227 DOI: 10.1016/J.Toxicon.2010.06.009  1
2009 Hanck DA, Nikitina E, McNulty MM, Fozzard HA, Lipkind GM, Sheets MF. Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity. Circulation Research. 105: 492-9. PMID 19661462 DOI: 10.1161/Circresaha.109.198572  1
2009 Kyle JW, Berthoud VM, Kurutz J, Minogue PJ, Greenspan M, Hanck DA, Beyer EC. The N terminus of connexin37 contains an alpha-helix that is required for channel function. The Journal of Biological Chemistry. 284: 20418-27. PMID 19478091 DOI: 10.1074/jbc.M109.016907  1
2008 Kyle JW, Minogue PJ, Thomas BC, Domowicz DA, Berthoud VM, Hanck DA, Beyer EC. An intact connexin N-terminus is required for function but not gap junction formation. Journal of Cell Science. 121: 2744-50. PMID 18664489 DOI: 10.1242/jcs.032482  1
2008 Edgerton GB, Blumenthal KM, Hanck DA. Evidence for multiple effects of ProTxII on activation gating in Na(V)1.5. Toxicon : Official Journal of the International Society On Toxinology. 52: 489-500. PMID 18657562 DOI: 10.1016/J.Toxicon.2008.06.023  1
2008 Bittner KC, Hanck DA. The relationship between single-channel and whole-cell conductance in the T-type Ca2+ channel CaV3.1. Biophysical Journal. 95: 931-41. PMID 18375519 DOI: 10.1529/Biophysj.107.128124  1
2007 Sheets MF, Hanck DA. Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels. The Journal of Physiology. 582: 317-34. PMID 17510181 DOI: 10.1113/jphysiol.2007.134262  1
2007 McNulty MM, Edgerton GB, Shah RD, Hanck DA, Fozzard HA, Lipkind GM. Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels. The Journal of Physiology. 581: 741-55. PMID 17363383 DOI: 10.1113/Jphysiol.2007.130161  1
2007 Hanck DA, Sheets MF. Site-3 toxins and cardiac sodium channels. Toxicon : Official Journal of the International Society On Toxinology. 49: 181-93. PMID 17092528 DOI: 10.1016/j.toxicon.2006.09.017  1
2006 McNulty MM, Kyle JW, Lipkind GM, Hanck DA. An inner pore residue (Asn406) in the Nav1.5 channel controls slow inactivation and enhances mibefradil block to T-type Ca2+ channel levels. Molecular Pharmacology. 70: 1514-23. PMID 16885209 DOI: 10.1124/Mol.106.027177  1
2006 Khan A, Kyle JW, Hanck DA, Lipkind GM, Fozzard HA. Isoform-dependent interaction of voltage-gated sodium channels with protons Journal of Physiology. 576: 493-501. PMID 16873405 DOI: 10.1113/jphysiol.2006.115659  1
2006 Freeze BS, McNulty MM, Hanck DA. State-dependent verapamil block of the cloned human Ca(v)3.1 T-type Ca(2+) channel. Molecular Pharmacology. 70: 718-26. PMID 16699084 DOI: 10.1124/Mol.106.023473  1
2006 Emerick MC, Stein R, Kunze R, McNulty MM, Regan MR, Hanck DA, Agnew WS. Profiling the array of Ca(v)3.1 variants from the human T-type calcium channel gene CACNA1G: alternative structures, developmental expression, and biophysical variations. Proteins. 64: 320-42. PMID 16671074 DOI: 10.1002/Prot.20877  1
2006 Zhong X, Liu JR, Kyle JW, Hanck DA, Agnew WS. A profile of alternative RNA splicing and transcript variation of CACNA1H, a human T-channel gene candidate for idiopathic generalized epilepsies. Human Molecular Genetics. 15: 1497-512. PMID 16565161 DOI: 10.1093/hmg/ddl068  1
2005 Lam AD, Chikina MD, McNulty MM, Glaaser IW, Hanck DA. Role of Domain IV/S4 outermost arginines in gating of T-type calcium channels. Pflã¼Gers Archiv : European Journal of Physiology. 451: 349-61. PMID 16133267 DOI: 10.1007/S00424-005-1407-5  1
2005 Sheets MF, Hanck DA. Charge immobilization of the voltage sensor in domain IV is independent of sodium current inactivation. The Journal of Physiology. 563: 83-93. PMID 15576449 DOI: 10.1113/jphysiol.2004.077644  1
2004 Sunami A, Tracey A, Glaaser IW, Lipkind GM, Hanck DA, Fozzard HA. Accessibility of mid-segment domain IV S6 residues of the voltage-gated Na+ channel to methanethiosulfonate reagents. The Journal of Physiology. 561: 403-13. PMID 15579536 DOI: 10.1113/jphysiol.2004.067579  1
2004 McNulty MM, Hanck DA. State-dependent mibefradil block of Na+ channels. Molecular Pharmacology. 66: 1652-61. PMID 15562257 DOI: 10.1124/Mol.66.6.1652  1
2004 Puljung MC, Berthoud VM, Beyer EC, Hanck DA. Polyvalent cations constitute the voltage gating particle in human connexin37 hemichannels. The Journal of General Physiology. 124: 587-603. PMID 15504903 DOI: 10.1085/Jgp.200409023  1
2004 Seibert AL, Liu J, Hanck DA, Blumenthal KM. Role of Asn-16 and Ser-19 in anthopleurin B binding. Implications for the electrostatic nature of Na(V) site 3. Biochemistry. 43: 7082-9. PMID 15170345 DOI: 10.1021/Bi0496135  1
2003 Seibert AL, Liu J, Hanck DA, Blumenthal KM. Arg-14 loop of site 3 anemone toxins: effects of glycine replacement on toxin affinity. Biochemistry. 42: 14515-21. PMID 14661964 DOI: 10.1021/Bi035291D  1
2003 Sheets MF, Hanck DA. Molecular action of lidocaine on the voltage sensors of sodium channels. The Journal of General Physiology. 121: 163-75. PMID 12566542 DOI: 10.1085/jgp.20028651  1
2002 Sheets MF, Hanck DA. The outermost lysine in the S4 of domain III contributes little to the gating charge in sodium channels. Biophysical Journal. 82: 3048-55. PMID 12023227 DOI: 10.1016/S0006-3495(02)75645-2  1
2000 Martin RL, Lee JH, Cribbs LL, Perez-Reyes E, Hanck DA. Mibefradil block of cloned T-type calcium channels. The Journal of Pharmacology and Experimental Therapeutics. 295: 302-8. PMID 10991994  1
2000 Martin RL, Pittendrigh B, Liu J, Reenan R, ffrench-Constant R, Hanck DA. Point mutations in domain III of a Drosophila neuronal Na channel confer resistance to allethrin. Insect Biochemistry and Molecular Biology. 30: 1051-9. PMID 10989292 DOI: 10.1016/S0965-1748(00)00080-1  1
2000 Hanck DA, Makielski JC, Sheets MF. Lidocaine alters activation gating of cardiac Na channels. PflüGers Archiv : European Journal of Physiology. 439: 814-21. PMID 10784357 DOI: 10.1007/S004249900217  1
2000 Sheets MF, Kyle JW, Hanck DA. The role of the putative inactivation lid in sodium channel gating current immobilization. The Journal of General Physiology. 115: 609-20. PMID 10779318 DOI: 10.1085/jgp.115.5.609  1
1999 Sheets MF, Kyle JW, Kallen RG, Hanck DA. The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4. Biophysical Journal. 77: 747-57. PMID 10423423 DOI: 10.1016/S0006-3495(99)76929-8  1
1999 Benzinger GR, Tonkovich GS, Hanck DA. Augmentation of recovery from inactivation by site-3 Na channel toxins. A single-channel and whole-cell study of persistent currents Journal of General Physiology. 113: 333-346. PMID 9925828 DOI: 10.1085/jgp.113.2.333  1
1999 Sheets MF, Hanck DA. Gating of skeletal and cardiac muscle sodium channels in mammalian cells. The Journal of Physiology. 514: 425-36. PMID 9852324 DOI: 10.1111/j.1469-7793.1999.425ae.x  1
1998 Hanck D. Heartthrobs Science. 279: 1004. PMID 9490476 DOI: 10.1126/science.279.5353.1004  1
1998 Millonas MM, Hanck DA. Nonequilibrium response spectroscopy of voltage-sensitive ion channel gating Biophysical Journal. 74: 210-229. PMID 9449324  1
1998 Benzinger GR, Kyle JW, Blumenthal KM, Hanck DA. A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B Journal of Biological Chemistry. 273: 80-84. PMID 9417050 DOI: 10.1074/jbc.273.1.80  1
1998 Millonas MM, Hanck DA. Nonequilibrium response spectroscopy and the molecular kinetics of proteins Physical Review Letters. 80: 401-404.  1
1997 Richard Benzinger G, Drum CL, Chen LQ, Kallen RG, Hanck DA. Differences in the binding sites of two site-3 sodium channel toxins Pflugers Archiv European Journal of Physiology. 434: 742-749. PMID 9306007 DOI: 10.1007/S004240050460  1
1996 Zeng D, Kyle JW, Martin RL, Ambler KS, Hanck D. Cardiac sodium channels expressed in a peripheral neurotumor-derived cell line, RT4-B8 American Journal of Physiology - Cell Physiology. 270. PMID 8967455  1
1996 Kelso GJ, Drum CL, Hanck DA, Blumenthal KM. Role for Pro-13 in directing high-affinity binding of anthopleurin B to the voltage-sensitive sodium channel Biochemistry. 35: 14157-14164. PMID 8916901 DOI: 10.1021/Bi961584D  1
1996 Sheets MF, Kyle JW, Krueger S, Hanck DA. Optimization of a mammalian expression system for the measurement of sodium channel gating currents. The American Journal of Physiology. 271: C1001-6. PMID 8843731  1
1996 Dias-Kadambi BL, Combs KA, Drum CL, Hanck DA, Blumenthal KM. The role of exposed tryptophan residues in the activity of the cardiotonic polypeptide anthopleurin B Journal of Biological Chemistry. 271: 23828-23835. PMID 8798612 DOI: 10.1074/Jbc.271.39.23828  1
1996 Fozzard HA, Hanck DA. Structure and function of voltage-dependent sodium channels: Comparison of brain II and cardiac isoforms Physiological Reviews. 76: 887-926. PMID 8757791  1
1996 Dias-Kadambi BL, Drum CL, Hanck DA, Blumenthal KM. Leucine 18, a hydrophobic residue essential for high affinity binding of anthopleurin B to the voltage-sensitive sodium channel Journal of Biological Chemistry. 271: 9422-9428. PMID 8621610 DOI: 10.1074/Jbc.271.16.9422  1
1996 Kelso GJ, Drum CL, Hanck DA, Blumenthal KM. Replacement of individual residues of anthopleurin b with those native to anthopleurin A: A functional analysis Faseb Journal. 10.  1
1995 Sheets MF, Hanck DA. Voltage-dependent open-state inactivation of cardiac sodium channels: gating current studies with Anthopleurin-A toxin. The Journal of General Physiology. 106: 617-40. PMID 8576700 DOI: 10.1085/jgp.106.4.617  1
1995 Hanck DA, Sheets MF. Modification of inactivation in cardiac sodium channels: ionic current studies with Anthopleurin-A toxin. The Journal of General Physiology. 106: 601-16. PMID 8576699 DOI: 10.1085/jgp.106.4.601  1
1995 Ono K, Fozzard HA, Hanck DA. A direct effect of forskolin on sodium channel bursting PflüGers Archiv European Journal of Physiology. 429: 561-569. PMID 7617447 DOI: 10.1007/BF00704162  1
1995 Khera PK, Benzinger GR, Lipkind G, Drum CL, Hanck DA, Blumenthal KM. Multiple cationic residues of anthopleurin B that determine high affinity and channel isoform discrimination Biochemistry. 34: 8533-8541. PMID 7612595 DOI: 10.1021/bi00027a003  1
1995 Lipkind GM, Hanck DA, Fozzard HA. A structural motif for the voltage-gated potassium channel pore Proceedings of the National Academy of Sciences of the United States of America. 92: 9215-9219. PMID 7568104 DOI: 10.1073/pnas.92.20.9215  1
1994 Hanck DA, Makielski JC, Sheets MF. Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study. The Journal of General Physiology. 103: 19-43. PMID 8169596 DOI: 10.1085/Jgp.103.1.19  1
1994 Page E, Goings GE, Upshaw-Earley J, Hanck DA. Endocytosis and uptake of Lucifer yellow by cultured atrial myocytes and isolated intact atria from adult rats: Regulation and subcellular localization Circulation Research. 75: 335-346. PMID 8033344  1
1994 Ono K, Hanck DA, Fozzard HA. Protein kinase a-dependent phosphorylation modulation of cardiac sodium channel kinetics Japanese Heart Journal. 35: 125-126.  1
1993 Ono K, Fozzard HA, Hanck DA. Mechanism of cAMP-dependent modulation of cardiac sodium channel current kinetics Circulation Research. 72: 807-815. PMID 8383015  1
1993 Sheets MF, Hanck DA. Modification of sodium channel inactivation by alpha-chymotrypsin in canine cardiac Purkinje cells. Journal of Cardiovascular Electrophysiology. 4: 686-94. PMID 8305988  1
1993 Page E, Upshaw-Earley J, Goings GE, Hanck DA. Fluid-phase endocytosis by in situ cardiac myocytes of rat atria American Journal of Physiology - Cell Physiology. 265. PMID 8238324  1
1992 El-Sherif N, Fozzard HA, Hanck DA. Dose-dependent modulation of the cardiac sodium channel by sea anemone toxin ATXII Circulation Research. 70: 285-301. PMID 1346508  1
1992 Sheets MF, Hanck DA. Mechanisms of extracellular divalent and trivalent cation block of the sodium current in canine cardiac Purkinje cells. The Journal of Physiology. 454: 299-320. PMID 1335503  1
1992 Hanck DA, Sheets MF. Extracellular divalent and trivalent cation effects on sodium current kinetics in single canine cardiac Purkinje cells. The Journal of Physiology. 454: 267-98. PMID 1335501  1
1992 Hanck DA, Sheets MF. Time-dependent changes in kinetics of Na+ current in single canine cardiac Purkinje cells. The American Journal of Physiology. 262: H1197-207. PMID 1314510  1
1991 Sheets MF, Hanck DA. Atrionatriuretic peptide and calcium-conducting sodium channels. Science (New York, N.Y.). 252: 449-52. PMID 1850170 DOI: 10.1126/Science.1850170  1
1991 Page E, Upshaw-Earley J, Goings GE, Hanck DA. Inhibition of atrial peptide secretion at different stages of the secretory process: Ca2+ dependence American Journal of Physiology - Cell Physiology. 261. PMID 1837420  1
1991 Page E, Upshaw-Earley J, Goings GE, Hanck DA. Effect of external Ca2+ concentration on stretch-augmented natriuretic peptide secretion by rat atria American Journal of Physiology - Cell Physiology. 260. PMID 1826817  1
1991 Makielski JC, Alpert LA, Hanck DA. Two components of use-dependent block of sodium current by lidocaine in voltage clamped cardiac Purkinje cells Journal of Molecular and Cellular Cardiology. 23: 95-102. PMID 1645416 DOI: 10.1016/0022-2828(91)90028-K  1
1990 Hanck DA, Sheets MF, Fozzard HA. Gating currents associated with Na channels in canine cardiac Purkinje cells. The Journal of General Physiology. 95: 439-57. PMID 2157792  1
1990 Scanley BE, Hanck DA, Chay T, Fozzard HA. Kinetic analysis of single sodium channels from canine cardiac Purkinje cells Journal of General Physiology. 95: 411-437. PMID 2157791  1
1989 Alpert LA, Fozzard HA, Hanck DA, Makielski JC. Is there a second external lidocaine binding site on mammalian cardiac cells? American Journal of Physiology - Heart and Circulatory Physiology. 257. PMID 2546451 DOI: 10.1152/Ajpheart.1989.257.1.H79  1
1989 Makielski JC, Hanck DA, Fozzard HA. Ionic channels, arrhythmias and antiarrhythmic drugs Electrocardiology 1988: Proceedings of the Xvth International Congress On Electrocardiology. Ics830. 27-30.  1
1988 Makielski JC, Undrovinas AI, Hanck DA, Sheets MF, Nesterenko VV, Alpert LA, Rosenshtraukh LV, Fozzard HA. Use-dependent block of sodium current by ethmozin in voltage-clamped internally perfused canine cardiac Purkinje cells. Journal of Molecular and Cellular Cardiology. 20: 255-65. PMID 2456399 DOI: 10.1016/S0022-2828(88)80058-0  1
1988 Sheets MF, Hanck DA, Fozzard HA. Nonlinear relation between Vmax and INa in canine cardiac Purkinje cells. Circulation Research. 63: 386-98. PMID 2456164  1
1987 Makielski JC, Sheets MF, Hanck DA, January CT, Fozzard HA. Sodium current in voltage clamped internally perfused canine cardiac Purkinje cells. Biophysical Journal. 52: 1-11. PMID 3607218 DOI: 10.1016/S0006-3495(87)83182-X  1
1987 Fozzard HA, Hanck DA, Makielski JC, Scanley BE, Sheets MF. Sodium channels in cardiac Purkinje cells. Experientia. 43: 1162-8. PMID 2446909 DOI: 10.1007/Bf01945516  1
1987 Sheets MF, Scanley BE, Hanck DA, Makielski JC, Fozzard HA. Open sodium channel properties of single canine cardiac Purkinje cells. Biophysical Journal. 52: 13-22. PMID 2440490 DOI: 10.1016/S0006-3495(87)83183-1  1
1986 Fozzard HA, Friedlander IR, Hanck DA, January CT, Makielski JC, Sheets MF. Sodium currents in single cardiac Purkinje cells. Journal of the American College of Cardiology. 8: 79A-85A. PMID 2423574 DOI: 10.1016/S0735-1097(86)80033-X  1
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