Cecilia M. Giachelli - Publications

Affiliations: 
Bioengineering University of Washington, Seattle, Seattle, WA 
Area:
Biomedical Engineering, Molecular Biology, Immunology

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Purwaningrum M, Giachelli CM, Osathanon T, Rattanapuchpong S, Sawangmake C. Dissecting specific Wnt components governing osteogenic differentiation potential by human periodontal ligament stem cells through interleukin-6. Scientific Reports. 13: 9055. PMID 37270571 DOI: 10.1038/s41598-023-35569-8  0.585
2018 Yamada S, Leaf EM, Chia JJ, Cox TC, Speer MY, Giachelli CM. PiT-2, a type III sodium-dependent phosphate transporter, protects against vascular calcification in mice with chronic kidney disease fed a high-phosphate diet. Kidney International. PMID 30041812 DOI: 10.1016/J.Kint.2018.05.015  0.381
2018 Durham AL, Speer MY, Scatena M, Giachelli CM, Shanahan CM. Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness. Cardiovascular Research. 114: 590-600. PMID 29514202 DOI: 10.1093/Cvr/Cvy010  0.391
2017 Jackson MF, Scatena M, Giachelli CM. Osteoclast precursors do not express CD68: results from CD68 promoter-driven RANK transgenic mice. Febs Letters. PMID 28173622 DOI: 10.1002/1873-3468.12588  0.325
2016 Yamada S, Giachelli CM. Vascular calcification in CKD-MBD: Roles for phosphate, FGF23, and Klotho. Bone. PMID 27847254 DOI: 10.1016/J.Bone.2016.11.012  0.361
2016 Lin ME, Chen TM, Wallingford MC, Nguyen NB, Yamada S, Sawangmake C, Zhang J, Speer MY, Giachelli CM. Runx2 Deletion in Smooth muscle Cells Inhibits Vascular Osteochondrogenesis and Calcification but not Atherosclerotic Lesion Formation. Cardiovascular Research. PMID 27671804 DOI: 10.1093/Cvr/Cvw205  0.381
2016 Paloian NJ, Leaf EM, Giachelli CM. Osteopontin protects against high phosphate-induced nephrocalcinosis and vascular calcification. Kidney International. 89: 1027-36. PMID 27083280 DOI: 10.1016/J.Kint.2015.12.046  0.338
2016 Wallingford MC, Chia J, Leaf EM, Borgeia S, Chavkin NW, Sawangmake C, Marro K, Cox TC, Speer MY, Giachelli CM. SLC20A2 deficiency in mice leads to elevated phosphate levels in cerbrospinal fluid and glymphatic pathway-associated arteriolar calcification, and recapitulates human idiopathic basal ganglia calcification. Brain Pathology (Zurich, Switzerland). PMID 26822507 DOI: 10.1111/Bpa.12362  0.368
2015 Eaton K, Yang H, Giachelli C, Scatena M. Engineering Macrophages to Control the Inflammatory Response and Angiogenesis. Experimental Cell Research. PMID 26610863 DOI: 10.1016/J.Yexcr.2015.11.021  0.364
2015 Lin ME, Chen T, Leaf EM, Speer MY, Giachelli CM. Runx2 Expression in Smooth Muscle Cells Is Required for Arterial Medial Calcification in Mice. The American Journal of Pathology. 185: 1958-69. PMID 25987250 DOI: 10.1016/J.Ajpath.2015.03.020  0.338
2015 Chavkin NW, Chia JJ, Crouthamel MH, Giachelli CM. Phosphate uptake-independent signaling functions of the type III sodium-dependent phosphate transporter, PiT-1, in vascular smooth muscle cells. Experimental Cell Research. 333: 39-48. PMID 25684711 DOI: 10.1016/J.Yexcr.2015.02.002  0.374
2014 Paloian NJ, Giachelli CM. A current understanding of vascular calcification in CKD. American Journal of Physiology. Renal Physiology. 307: F891-900. PMID 25143458 DOI: 10.1152/Ajprenal.00163.2014  0.317
2014 Wallingford MC, Giachelli CM. Loss of PiT-1 results in abnormal endocytosis in the yolk sac visceral endoderm. Mechanisms of Development. 133: 189-202. PMID 25138534 DOI: 10.1016/J.Mod.2014.08.001  0.33
2014 Tung JC, Paige SL, Ratner BD, Murry CE, Giachelli CM. Engineered biomaterials control differentiation and proliferation of human-embryonic-stem-cell-derived cardiomyocytes via timed Notch activation. Stem Cell Reports. 2: 271-81. PMID 24672751 DOI: 10.1016/J.Stemcr.2014.01.011  0.666
2013 Rementer CW, Wu M, Buranaphatthana W, Yang HY, Scatena M, Giachelli CM. An inducible, ligand-independent receptor activator of NF-κB gene to control osteoclast differentiation from monocytic precursors. Plos One. 8: e84465. PMID 24386387 DOI: 10.1371/Journal.Pone.0084465  0.405
2013 Crouthamel MH, Lau WL, Leaf EM, Chavkin NW, Wallingford MC, Peterson DF, Li X, Liu Y, Chin MT, Levi M, Giachelli CM. Sodium-dependent phosphate cotransporters and phosphate-induced calcification of vascular smooth muscle cells: redundant roles for PiT-1 and PiT-2. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2625-32. PMID 23968976 DOI: 10.1161/Atvbaha.113.302249  0.414
2013 Wu M, Rementer C, Giachelli CM. Vascular calcification: an update on mechanisms and challenges in treatment. Calcified Tissue International. 93: 365-73. PMID 23456027 DOI: 10.1007/S00223-013-9712-Z  0.352
2013 Scialla JJ, Lau WL, Reilly MP, Isakova T, Yang HY, Crouthamel MH, Chavkin NW, Rahman M, Wahl P, Amaral AP, Hamano T, Master SR, Nessel L, Chai B, Xie D, ... ... Giachelli CM, et al. Fibroblast growth factor 23 is not associated with and does not induce arterial calcification. Kidney International. 83: 1159-68. PMID 23389416 DOI: 10.1038/Ki.2013.3  0.333
2013 Liu L, Sánchez-Bonilla M, Crouthamel M, Giachelli C, Keel S. Mice lacking the sodium-dependent phosphate import protein, PiT1 (SLC20A1), have a severe defect in terminal erythroid differentiation and early B cell development. Experimental Hematology. 41: 432-43.e7. PMID 23376999 DOI: 10.1016/J.Exphem.2013.01.004  0.379
2013 Thomson KS, Korte FS, Giachelli CM, Ratner BD, Regnier M, Scatena M. Prevascularized microtemplated fibrin scaffolds for cardiac tissue engineering applications. Tissue Engineering. Part A. 19: 967-77. PMID 23317311 DOI: 10.1089/Ten.Tea.2012.0286  0.433
2013 Nguyen AT, Gomez D, Bell RD, Campbell JH, Clowes AW, Gabbiani G, Giachelli CM, Parmacek MS, Raines EW, Rusch NJ, Speer MY, Sturek M, Thyberg J, Towler DA, Weiser-Evans MC, et al. Smooth muscle cell plasticity: fact or fiction? Circulation Research. 112: 17-22. PMID 23093573 DOI: 10.1161/Circresaha.112.281048  0.406
2013 Osathanon T, Ritprajak P, Nowwarote N, Manokawinchoke J, Giachelli C, Pavasant P. Surface-bound orientated Jagged-1 enhances osteogenic differentiation of human periodontal ligament-derived mesenchymal stem cells. Journal of Biomedical Materials Research. Part A. 101: 358-67. PMID 22847978 DOI: 10.1002/Jbm.A.34332  0.647
2012 Deuell KA, Callegari A, Giachelli CM, Rosenfeld ME, Scatena M. RANKL enhances macrophage paracrine pro-calcific activity in high phosphate-treated smooth muscle cells: dependence on IL-6 and TNF-α. Journal of Vascular Research. 49: 510-21. PMID 22948607 DOI: 10.1159/000341216  0.37
2012 Lau WL, Leaf EM, Hu MC, Takeno MM, Kuro-o M, Moe OW, Giachelli CM. Vitamin D receptor agonists increase klotho and osteopontin while decreasing aortic calcification in mice with chronic kidney disease fed a high phosphate diet. Kidney International. 82: 1261-70. PMID 22932118 DOI: 10.1038/Ki.2012.322  0.341
2012 Naik V, Leaf EM, Hu JH, Yang HY, Nguyen NB, Giachelli CM, Speer MY. Sources of cells that contribute to atherosclerotic intimal calcification: an in vivo genetic fate mapping study. Cardiovascular Research. 94: 545-54. PMID 22436847 DOI: 10.1093/Cvr/Cvs126  0.356
2012 Kacherovsky N, Harkey MA, Blau CA, Giachelli CM, Pun SH. Combination of Sleeping Beauty transposition and chemically induced dimerization selection for robust production of engineered cells. Nucleic Acids Research. 40: e85. PMID 22402491 DOI: 10.1093/Nar/Gks213  0.329
2012 Liu L, Sanchez-Bonilla M, Crouthamel M, Giachelli C, Keel SB. Murine Terminal Erythroid Differentiation and Early B Development Require the Sodium-Dependent Phosphate Import Protein, PiT1. Blood. 120: 2307-2307. DOI: 10.1182/Blood.V120.21.2307.2307  0.372
2011 Shanahan CM, Crouthamel MH, Kapustin A, Giachelli CM. Arterial calcification in chronic kidney disease: key roles for calcium and phosphate. Circulation Research. 109: 697-711. PMID 21885837 DOI: 10.1161/Circresaha.110.234914  0.342
2011 Lau WL, Pai A, Moe SM, Giachelli CM. Direct effects of phosphate on vascular cell function. Advances in Chronic Kidney Disease. 18: 105-12. PMID 21406295 DOI: 10.1053/J.Ackd.2010.12.002  0.411
2011 Pai A, Leaf EM, El-Abbadi M, Giachelli CM. Elastin degradation and vascular smooth muscle cell phenotype change precede cell loss and arterial medial calcification in a uremic mouse model of chronic kidney disease. The American Journal of Pathology. 178: 764-73. PMID 21281809 DOI: 10.1016/J.Ajpath.2010.10.006  0.377
2011 Liu L, Sanchez-Bonilla M, Wang Y, Crouthamel M, Giachelli C, Keel SB. Mice Lacking the Sodium-Dependent Phosphate Import Protein, Pit-1, Have a Severe Defect in Terminal Erythroid Differentiation Blood. 118: 681-681. DOI: 10.1182/Blood.V118.21.681.681  0.342
2010 Pai AS, Giachelli CM. Matrix remodeling in vascular calcification associated with chronic kidney disease. Journal of the American Society of Nephrology : Jasn. 21: 1637-40. PMID 20798261 DOI: 10.1681/Asn.2010040349  0.326
2010 Lau WL, Festing MH, Giachelli CM. Phosphate and vascular calcification: Emerging role of the sodium-dependent phosphate co-transporter PiT-1. Thrombosis and Haemostasis. 104: 464-70. PMID 20664908 DOI: 10.1160/Th09-12-0814  0.391
2010 Yao Y, Bennett BJ, Wang X, Rosenfeld ME, Giachelli C, Lusis AJ, Boström KI. Inhibition of bone morphogenetic proteins protects against atherosclerosis and vascular calcification. Circulation Research. 107: 485-94. PMID 20576934 DOI: 10.1161/Circresaha.110.219071  0.316
2010 Speer MY, Li X, Hiremath PG, Giachelli CM. Runx2/Cbfa1, but not loss of myocardin, is required for smooth muscle cell lineage reprogramming toward osteochondrogenesis. Journal of Cellular Biochemistry. 110: 935-47. PMID 20564193 DOI: 10.1002/Jcb.22607  0.418
2010 Thomson KS, Robinson G, Korte FS, Giachelli C, Ratner BD, Scatena M, Regnier M. Cell-Seeded Fibrin Scaffolds for Cardiac Tissue Engineering Biophysical Journal. 98: 718a. DOI: 10.1016/J.Bpj.2009.12.3936  0.428
2009 Ahmad PJ, Trcka D, Xue S, Franco C, Speer MY, Giachelli CM, Bendeck MP. Discoidin domain receptor-1 deficiency attenuates atherosclerotic calcification and smooth muscle cell-mediated mineralization. The American Journal of Pathology. 175: 2686-96. PMID 19893047 DOI: 10.2353/Ajpath.2009.080734  0.427
2009 Festing MH, Speer MY, Yang HY, Giachelli CM. Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1. Genesis (New York, N.Y. : 2000). 47: 858-63. PMID 19882669 DOI: 10.1002/Dvg.20577  0.365
2009 Lund SA, Giachelli CM, Scatena M. The role of osteopontin in inflammatory processes. Journal of Cell Communication and Signaling. 3: 311-22. PMID 19798593 DOI: 10.1007/S12079-009-0068-0  0.332
2009 Osathanon T, Giachelli CM, Somerman MJ. Immobilization of alkaline phosphatase on microporous nanofibrous fibrin scaffolds for bone tissue engineering. Biomaterials. 30: 4513-21. PMID 19501906 DOI: 10.1016/J.Biomaterials.2009.05.022  0.645
2009 El-Abbadi MM, Pai AS, Leaf EM, Yang HY, Bartley BA, Quan KK, Ingalls CM, Liao HW, Giachelli CM. Phosphate feeding induces arterial medial calcification in uremic mice: role of serum phosphorus, fibroblast growth factor-23, and osteopontin. Kidney International. 75: 1297-307. PMID 19322138 DOI: 10.1038/Ki.2009.83  0.336
2009 Speer MY, Yang HY, Brabb T, Leaf E, Look A, Lin WL, Frutkin A, Dichek D, Giachelli CM. Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries. Circulation Research. 104: 733-41. PMID 19197075 DOI: 10.1161/Circresaha.108.183053  0.436
2009 Giachelli CM. The emerging role of phosphate in vascular calcification. Kidney International. 75: 890-7. PMID 19145240 DOI: 10.1038/Ki.2008.644  0.383
2009 McGonigle JS, Giachelli CM, Scatena M. Osteoprotegerin and RANKL differentially regulate angiogenesis and endothelial cell function. Angiogenesis. 12: 35-46. PMID 19105036 DOI: 10.1007/S10456-008-9127-Z  0.376
2009 Beckstead BL, Tung JC, Liang KJ, Tavakkol Z, Usui ML, Olerud JE, Giachelli CM. Methods to promote Notch signaling at the biomaterial interface and evaluation in a rafted organ culture model. Journal of Biomedical Materials Research. Part A. 91: 436-46. PMID 18985776 DOI: 10.1002/Jbm.A.32214  0.759
2009 Rajachar RM, Tung E, Truong AQ, Look A, Giachelli CM. Role of carbonic anhydrase II in ectopic calcification. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 18: 77-82. PMID 18402839 DOI: 10.1016/J.Carpath.2007.11.004  0.33
2009 Chang MW, Osathanon T, Giachelli C. Treating heterotopic ossification with shockwaves. The Journal of the Acoustical Society of America. 125: 2649-2649. DOI: 10.1121/1.4784138  0.588
2008 Osathanon T, Linnes ML, Rajachar RM, Ratner BD, Somerman MJ, Giachelli CM. Microporous nanofibrous fibrin-based scaffolds for bone tissue engineering. Biomaterials. 29: 4091-9. PMID 18640716 DOI: 10.1016/J.Biomaterials.2008.06.030  0.656
2008 Bhrany AD, Lien CJ, Beckstead BL, Futran ND, Muni NH, Giachelli CM, Ratner BD. Crosslinking of an oesophagus acellular matrix tissue scaffold. Journal of Tissue Engineering and Regenerative Medicine. 2: 365-72. PMID 18618611 DOI: 10.1002/Term.105  0.776
2008 Rajachar RM, Truong AQ, Giachelli CM. The influence of surface mineral and osteopontin on the formation and function of murine bone marrow-derived osteoclasts. Journal of Materials Science. Materials in Medicine. 19: 3279-85. PMID 18483788 DOI: 10.1007/S10856-008-3455-9  0.365
2008 Li X, Yang HY, Giachelli CM. BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells. Atherosclerosis. 199: 271-7. PMID 18179800 DOI: 10.1016/J.Atherosclerosis.2007.11.031  0.432
2008 Li X, El-Abbadi M, Giachelli CM. 87: Active Vitamin D Analogues Do Not Directly Affect Vascular Smooth Muscle Cell Calcification, but Induce a Procalcific to Anticalcific Paracrine Switch in Co-Cultured Human Macrophages American Journal of Kidney Diseases. 51: B49. DOI: 10.1053/J.Ajkd.2008.02.093  0.347
2007 Linnes MP, Ratner BD, Giachelli CM. A fibrinogen-based precision microporous scaffold for tissue engineering. Biomaterials. 28: 5298-306. PMID 17765302 DOI: 10.1016/J.Biomaterials.2007.08.020  0.407
2007 Scatena M, Liaw L, Giachelli CM. Osteopontin: a multifunctional molecule regulating chronic inflammation and vascular disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2302-9. PMID 17717292 DOI: 10.1161/Atvbaha.107.144824  0.363
2007 Saul JM, Linnes MP, Ratner BD, Giachelli CM, Pun SH. Delivery of non-viral gene carriers from sphere-templated fibrin scaffolds for sustained transgene expression. Biomaterials. 28: 4705-16. PMID 17675152 DOI: 10.1016/J.Biomaterials.2007.07.026  0.349
2007 Li X, Giachelli CM. Sodium-dependent phosphate cotransporters and vascular calcification. Current Opinion in Nephrology and Hypertension. 16: 325-8. PMID 17565274 DOI: 10.1097/Mnh.0B013E3281C55Ef1  0.322
2007 El-Abbadi M, Giachelli CM. Mechanisms of vascular calcification. Advances in Chronic Kidney Disease. 14: 54-66. PMID 17200044 DOI: 10.1053/J.Ackd.2006.10.007  0.345
2007 Raggi P, Giachelli C, Bellasi A. Interaction of vascular and bone disease in patients with normal renal function and patients undergoing dialysis. Nature Clinical Practice. Cardiovascular Medicine. 4: 26-33. PMID 17180147 DOI: 10.1038/Ncpcardio0725  0.341
2007 Ketteler M, Giachelli C. Novel insights into vascular calcification. Kidney International. Supplement. S5-9. PMID 17136112 DOI: 10.1038/Sj.Ki.5001996  0.377
2006 Fukano Y, Knowles NG, Usui ML, Underwood RA, Hauch KD, Marshall AJ, Ratner BD, Giachelli C, Carter WG, Fleckman P, Olerud JE. Characterization of an in vitro model for evaluating the interface between skin and percutaneous biomaterials. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 14: 484-91. PMID 16939578 DOI: 10.1111/J.1743-6109.2006.00138.X  0.355
2006 Rice J, Courter DL, Giachelli CM, Scatena M. Molecular mediators of alphavbeta3-induced endothelial cell survival. Journal of Vascular Research. 43: 422-36. PMID 16888388 DOI: 10.1159/000094884  0.321
2006 Beckstead BL, Santosa DM, Giachelli CM. Mimicking cell-cell interactions at the biomaterial-cell interface for control of stem cell differentiation. Journal of Biomedical Materials Research. Part A. 79: 94-103. PMID 16758464 DOI: 10.1002/Jbm.A.30760  0.78
2006 Bhrany AD, Beckstead BL, Lang TC, Farwell DG, Giachelli CM, Ratner BD. Development of an esophagus acellular matrix tissue scaffold. Tissue Engineering. 12: 319-30. PMID 16548690 DOI: 10.1089/Ten.2006.12.319  0.787
2006 Li X, Yang HY, Giachelli CM. Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification. Circulation Research. 98: 905-12. PMID 16527991 DOI: 10.1161/01.Res.0000216409.20863.E7  0.418
2005 Giachelli CM. Inducers and inhibitors of biomineralization: Lessons from pathological calcification Orthodontics and Craniofacial Research. 8: 229-231. PMID 16238602 DOI: 10.1111/J.1601-6343.2005.00345.X  0.432
2005 Tsai AT, Rice J, Scatena M, Liaw L, Ratner BD, Giachelli CM. The role of osteopontin in foreign body giant cell formation. Biomaterials. 26: 5835-43. PMID 15949549 DOI: 10.1016/J.Biomaterials.2005.03.003  0.348
2005 Liu L, Chen S, Giachelli CM, Ratner BD, Jiang S. Controlling osteopontin orientation on surfaces to modulate endothelial cell adhesion. Journal of Biomedical Materials Research. Part A. 74: 23-31. PMID 15920735 DOI: 10.1002/Jbm.A.30221  0.361
2005 Beckstead BL, Pan S, Bhrany AD, Bratt-Leal AM, Ratner BD, Giachelli CM. Esophageal epithelial cell interaction with synthetic and natural scaffolds for tissue engineering. Biomaterials. 26: 6217-28. PMID 15913763 DOI: 10.1016/J.Biomaterials.2005.04.010  0.786
2005 Giachelli CM, Speer MY, Li X, Rajachar RM, Yang H. Regulation of vascular calcification: roles of phosphate and osteopontin. Circulation Research. 96: 717-22. PMID 15831823 DOI: 10.1161/01.Res.0000161997.24797.C0  0.37
2005 Speer MY, Chien YC, Quan M, Yang HY, Vali H, McKee MD, Giachelli CM. Smooth muscle cells deficient in osteopontin have enhanced susceptibility to calcification in vitro. Cardiovascular Research. 66: 324-33. PMID 15820201 DOI: 10.1016/J.Cardiores.2005.01.023  0.378
2005 Ohri R, Tung E, Rajachar R, Giachelli CM. Mitigation of ectopic calcification in osteopontin-deficient mice by exogenous osteopontin. Calcified Tissue International. 76: 307-15. PMID 15812576 DOI: 10.1007/S00223-004-0071-7  0.741
2005 Courter DL, Lomas L, Scatena M, Giachelli CM. Src kinase activity is required for integrin alphaVbeta3-mediated activation of nuclear factor-kappaB. The Journal of Biological Chemistry. 280: 12145-51. PMID 15695822 DOI: 10.1074/Jbc.M412555200  0.315
2005 Bhrany A, Futran ND, Lien C, Muni NH, Irvin CA, Ratner BD, Giachelli CM. Cross-Linking of an Esophagus Acellular Matrix Tissue-Scaffold Otolaryngology-Head and Neck Surgery. 133. DOI: 10.1016/J.Otohns.2005.05.234  0.333
2005 Hahn SK, Ohri R, Giachelli CM. Anti-calcification of bovine pericardium for bioprosthetic heart valves after surface modification with hyaluronic acid derivatives Biotechnology and Bioprocess Engineering. 10: 218-224. DOI: 10.1007/Bf02932016  0.723
2004 Giachelli CM. Vascular calcification mechanisms. Journal of the American Society of Nephrology : Jasn. 15: 2959-64. PMID 15579497 DOI: 10.1097/01.Asn.0000145894.57533.C4  0.348
2004 Kyriakides TR, Foster MJ, Keeney GE, Tsai A, Giachelli CM, Clark-Lewis I, Rollins BJ, Bornstein P. The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation. The American Journal of Pathology. 165: 2157-66. PMID 15579457 DOI: 10.1016/S0002-9440(10)63265-8  0.341
2004 Yang H, Curinga G, Giachelli CM. Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro. Kidney International. 66: 2293-9. PMID 15569318 DOI: 10.1111/J.1523-1755.2004.66015.X  0.753
2004 Giachelli CM. Mechanisms of vascular calcification in uremia. Seminars in Nephrology. 24: 401-2. PMID 15490398 DOI: 10.1016/J.Semnephrol.2004.06.005  0.365
2004 Fischer JW, Steitz SA, Johnson PY, Burke A, Kolodgie F, Virmani R, Giachelli C, Wight TN. Decorin promotes aortic smooth muscle cell calcification and colocalizes to calcified regions in human atherosclerotic lesions. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 2391-6. PMID 15472131 DOI: 10.1161/01.Atv.0000147029.63303.28  0.372
2004 Ohri R, Hahn SK, Hoffman AS, Stayton PS, Giachelli CM. Hyaluronic acid grafting mitigates calcification of glutaraldehyde-fixed bovine pericardium. Journal of Biomedical Materials Research. Part A. 70: 328-34. PMID 15227678 DOI: 10.1002/Jbm.A.30088  0.731
2004 Martin SM, Schwartz JL, Giachelli CM, Ratner BD. Enhancing the biological activity of immobilized osteopontin using a type-1 collagen affinity coating. Journal of Biomedical Materials Research. Part A. 70: 10-9. PMID 15174104 DOI: 10.1002/Jbm.A.30052  0.652
2004 Pritzker LB, Scatena M, Giachelli CM. The role of osteoprotegerin and tumor necrosis factor-related apoptosis-inducing ligand in human microvascular endothelial cell survival. Molecular Biology of the Cell. 15: 2834-41. PMID 15064358 DOI: 10.1091/Mbc.E04-01-0059  0.335
2004 Speer MY, Giachelli CM. Regulation of cardiovascular calcification. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 13: 63-70. PMID 15033154 DOI: 10.1016/S1054-8807(03)00130-3  0.33
2004 Speer MY, Chien Y, Quan M, McKee MD, Giachelli CM. OSTEOPONTIN INHIBITS SMOOTH MUSCLE CELL CALCIFICATION VIA AN AUTOCRINE MECHANISM THAT MAY INVOLVE BOTH RGD-DEPENDENT AND -INDEPENDENT PATHWAYS Cardiovascular Pathology. 13: 187. DOI: 10.1016/J.Carpath.2004.03.562  0.342
2004 Li X, Giachelli CM. THE ROLE OF TYPE III SODIUM-DEPENDENT PHOSPHATE COTRANSPORTER PIT-1 IN SMOOTH MUSCLE CELL CALCIFICATION Cardiovascular Pathology. 13: 185. DOI: 10.1016/J.Carpath.2004.03.557  0.338
2004 McGonigle J, Giachelli C, Scatena M. OSTEOPROTEGERIN PROMOTES ENDOTHELIAL CELL SURVIVAL AND ANGIOGENESIS Cardiovascular Pathology. 13: 181-182. DOI: 10.1016/J.Carpath.2004.03.546  0.337
2004 Speer MY, Giachelli CM. PHENOTYPIC MODULATION OF SMOOTH MUSCLE CELLS IN CALCIFIED ARTERIES: AN ON-AND-OFF EFFECT ASSOCIATED WITH CULTURE ENVIRONMENT Cardiovascular Pathology. 13: 162. DOI: 10.1016/J.Carpath.2004.03.489  0.327
2004 Scatena M, Pritzker L, Giachelli CM. OSTEOPROTEGERIN AN AVB3-INDUCED ENDOTHELIAL CELL SURVIVAL MOLECULE Cardiovascular Pathology. 13: 3-4. DOI: 10.1016/J.Carpath.2004.03.004  0.322
2003 Cuy JL, Beckstead BL, Brown CD, Hoffman AS, Giachelli CM. Adhesive protein interactions with chitosan: consequences for valve endothelial cell growth on tissue-engineering materials. Journal of Biomedical Materials Research. Part A. 67: 538-47. PMID 14566796 DOI: 10.1002/Jbm.A.10095  0.785
2003 Martin SM, Ganapathy R, Kim TK, Leach-Scampavia D, Giachelli CM, Ratner BD. Characterization and analysis of osteopontin-immobilized poly(2-hydroxyethyl methacrylate) surfaces. Journal of Biomedical Materials Research. Part A. 67: 334-43. PMID 14517893 DOI: 10.1002/Jbm.A.10060  0.613
2003 Gilbert M, Giachelli CM, Stayton PS. Biomimetic peptides that engage specific integrin-dependent signaling pathways and bind to calcium phosphate surfaces. Journal of Biomedical Materials Research. Part A. 67: 69-77. PMID 14517863 DOI: 10.1002/Jbm.A.10053  0.339
2003 Giachelli CM. Vascular calcification: in vitro evidence for the role of inorganic phosphate. Journal of the American Society of Nephrology : Jasn. 14: S300-4. PMID 12939385 DOI: 10.1097/01.Asn.0000081663.52165.66  0.431
2003 Ismail JA, Poppa V, Kemper LE, Scatena M, Giachelli CM, Coffin JD, Murry CE. Immunohistologic labeling of murine endothelium. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 12: 82-90. PMID 12684163 DOI: 10.1016/S1054-8807(02)00166-7  0.377
2002 Steitz SA, Speer MY, McKee MD, Liaw L, Almeida M, Yang H, Giachelli CM. Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification. The American Journal of Pathology. 161: 2035-46. PMID 12466120 DOI: 10.1016/S0002-9440(10)64482-3  0.401
2002 Speer MY, McKee MD, Guldberg RE, Liaw L, Yang HY, Tung E, Karsenty G, Giachelli CM. Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo. The Journal of Experimental Medicine. 196: 1047-55. PMID 12391016 DOI: 10.1084/Jem.20020911  0.365
2002 Mazzali M, Hughes J, Dantas M, Liaw L, Steitz S, Alpers CE, Pichler RH, Lan HY, Giachelli CM, Shankland SJ, Couser WG, Johnson RJ. Effects of cyclosporine in osteopontin null mice. Kidney International. 62: 78-85. PMID 12081566 DOI: 10.1046/J.1523-1755.2002.00408.X  0.331
2002 Dichtl W, Ares MP, Jönson AN, Jovinge S, Pachinger O, Giachelli CM, Hamsten A, Eriksson P, Nilsson J. Linoleic acid-stimulated vascular adhesion molecule-1 expression in endothelial cells depends on nuclear factor-kappaB activation. Metabolism: Clinical and Experimental. 51: 327-33. PMID 11887169 DOI: 10.1053/Meta.2002.29963  0.372
2002 Scatena M, Giachelli C. The alpha(v)beta3 integrin, NF-kappaB, osteoprotegerin endothelial cell survival pathway. Potential role in angiogenesis. Trends in Cardiovascular Medicine. 12: 83-8. PMID 11852256 DOI: 10.1016/S1050-1738(01)00151-7  0.401
2001 Steitz SA, Speer MY, Curinga G, Yang HY, Haynes P, Aebersold R, Schinke T, Karsenty G, Giachelli CM. Smooth muscle cell phenotypic transition associated with calcification: Upregulation of Cbfa1 and downregulation of smooth muscle lineage markers Circulation Research. 89: 1147-1154. PMID 11739279 DOI: 10.1161/Hh2401.101070  0.78
2001 Giachelli CM, Jono S, Shioi A, Nishizawa Y, Mori K, Morii H. Vascular calcification and inorganic phosphate American Journal of Kidney Diseases. 38. PMID 11576919 DOI: 10.1053/Ajkd.2001.27394  0.391
2001 Hudkins KL, Le QC, Segerer S, Johnson RJ, Davis CL, Giachelli CM, Alpers CE. Osteopontin expression in human cyclosporine toxicity Kidney International. 60: 635-640. PMID 11473646 DOI: 10.1046/J.1523-1755.2001.060002635.X  0.328
2001 Giachelli CM. Ectopic calcification: New concepts in cellular regulation Zeitschrift Fur Kardiologie. 90: 31-37. PMID 11374030  0.348
2000 Giachelli CM, Steitz S. Osteopontin: a versatile regulator of inflammation and biomineralization Matrix Biology. 19: 615-622. PMID 11102750 DOI: 10.1016/S0945-053X(00)00108-6  0.421
2000 Jono S, McKee MD, Murry CE, Shioi A, Nishizawa Y, Mori K, Morii H, Giachelli CM. Phosphate regulation of vascular smooth muscle cell calcification Circulation Research. 87. PMID 11009570 DOI: 10.1161/01.Res.87.7.E10  0.417
2000 Bendeck MP, Irvin C, Reidy M, Smith L, Mulholland D, Horton M, Giachelli CM. Smooth muscle cell matrix metalloproteinase production is stimulated via α(v)/β3 integrin Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 1467-1472. PMID 10845859 DOI: 10.1161/01.Atv.20.6.1467  0.307
2000 Malyankar UM, Scatena M, Suchland KL, Yun TJ, Clark EA, Giachelli CM. Osteoprotegerin is an α(v)β3-induced, NF-κB-dependent survival factor for endothelial cells Journal of Biological Chemistry. 275: 20959-20962. PMID 10811631 DOI: 10.1074/Jbc.C000290200  0.344
2000 Jono S, Peinado C, Giachelli CM. Phosphorylation of osteopontin is required for inhibition of vascular smooth muscle cell calcification Journal of Biological Chemistry. 275: 20197-20203. PMID 10766759 DOI: 10.1074/Jbc.M909174199  0.367
2000 Gilbert M, Shaw WJ, Long JR, Nelson K, Drobny GP, Giachelli CM, Stayton PS. Chimeric peptides of statherin and osteopontin that bind hydroxyapatite and mediate cell adhesion. The Journal of Biological Chemistry. 275: 16213-8. PMID 10748043 DOI: 10.1074/Jbc.M001773200  0.327
2000 Garrison MD, McDevitt TC, Luginbühl R, Giachelli CM, Stayton P, Ratner BD. Quantitative interrogation of micropatterned biomolecules by surface force microscopy Ultramicroscopy. 82: 193-202. PMID 10741670 DOI: 10.1016/S0304-3991(99)00150-3  0.332
2000 Hudkins KL, Giachelli CM, Eitner F, Couser WG, Johnson RJ, Alpers CE. Osteopontin expression in human crescentic glomerulonephritis Kidney International. 57: 105-116. PMID 10620192 DOI: 10.1046/J.1523-1755.2000.00813.X  0.374
1999 Ophascharoensuk V, Giachelli CM, Gordon K, Hughes J, Pichler R, Brown P, Liaw L, Schmidt R, Shankland SJ, Alpers CE, Couser WG, Johnson RJ. Obstructive uropathy in the mouse: Role of osteopontin in interstitial fibrosis and apoptosis Kidney International. 56: 571-580. PMID 10432396 DOI: 10.1046/J.1523-1755.1999.00580.X  0.335
1999 Malyankar UM, Hanson R, Schwartz SM, Ridall AL, Giachelli CM. Upstream stimulatory factor 1 regulates osteopontin expression in smooth muscle cells Experimental Cell Research. 250: 535-547. PMID 10413606 DOI: 10.1006/Excr.1999.4537  0.386
1999 Giachelli CM. Ectopic calcification: Gathering hard facts about soft tissue mineralization American Journal of Pathology. 154: 671-675. PMID 10079244 DOI: 10.1016/S0002-9440(10)65313-8  0.364
1999 Wada T, McKee MD, Steitz S, Giachelli CM. Calcification of vascular smooth muscle cell cultures: Inhibition by osteopontin Circulation Research. 84: 166-178. PMID 9933248 DOI: 10.1161/01.Res.84.2.166  0.426
1998 Thomas SE, Lombardi D, Giachelli C, Bohle A, Johnson RJ. Osteopontin expression, tubulointerstitial disease, and essential hypertension American Journal of Hypertension. 11: 954-961. PMID 9715788 DOI: 10.1016/S0895-7061(98)00091-0  0.322
1998 Smith LL, Giachelli CM. Structural requirements for α9β1-mediated adhesion and migration to thrombin-cleaved osteopontin Experimental Cell Research. 242: 351-360. PMID 9665832 DOI: 10.1006/Excr.1998.4108  0.343
1998 Scatena M, Almeida M, Chaisson ML, Fausto N, Nicosia RF, Giachelli CM. NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival. The Journal of Cell Biology. 141: 1083-93. PMID 9585425 DOI: 10.1083/Jcb.141.4.1083  0.32
1997 Graf K, Do YS, Ashizawa N, Meehan WP, Giachelli CM, Marboe CC, Fleck E, Hsueh WA. Myocardial osteopontin expression is associated with left ventricular hypertrophy Circulation. 96: 3063-3071. PMID 9386176 DOI: 10.1161/01.Cir.96.9.3063  0.304
1997 Malyankar UM, Almeida M, Johnson RJ, Pichler RH, Giachelli CM. Osteopontin regulation in cultured rat renal epithelial cells Kidney International. 51: 1766-1773. PMID 9186865 DOI: 10.1038/Ki.1997.243  0.369
1997 Liaw L, Lombardi DM, Almeida MM, Schwartz SM, DeBlois D, Giachelli CM. Neutralizing antibodies directed against osteopontin inhibit rat carotid neointimal thickening after endothelial denudation Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 188-193. PMID 9012655 DOI: 10.1161/01.Atv.17.1.188  0.335
1997 Giachelli CM, Scatena M, Wada T. Osteopontin: Potential roles in vascular function and dystrophic calcification Journal of Bone and Mineral Metabolism. 15: 179-183. DOI: 10.1007/Bf02491379  0.307
1996 DeBlois D, Lombardi DM, Su EJ, Clowes AW, Schwartz SM, Giachelli CM. Angiotensin II induction of osteopontin expression and DNA replication in rat arteries Hypertension. 28: 1055-1063. PMID 8952596 DOI: 10.1161/01.Hyp.28.6.1055  0.361
1996 Ashizawa N, Graf K, Do YS, Nunohiro T, Giachelli CM, Meehan WP, Tuan TL, Hsueh WA. Osteopontin is produced by rat cardiac fibroblasts and mediates A(II)- induced DNA synthesis and collagen gel contraction Journal of Clinical Investigation. 98: 2218-2227. PMID 8941637 DOI: 10.1172/Jci119031  0.33
1996 Smith LL, Cheung HK, Lingg LE, Chen J, Sheppard D, Pytela R, Giachelli CM. Osteopontin N-terminal domain contains a cryptic adhesive sequence recognized by α9β1 integrin Journal of Biological Chemistry. 271: 28485-28491. PMID 8910476 DOI: 10.1074/Jbc.271.45.28485  0.333
1996 Bendeck MP, Regenass S, David Tom W, Giachelli CM, Schwartz SM, Hart C, Reidy MA. Differential expression of α1 type VIII collagen in injured platelet- derived growth factor-BB-stimulated rat carotid arteries Circulation Research. 79: 524-531. PMID 8781485 DOI: 10.1161/01.Res.79.3.524  0.381
1996 Murry CE, Bartosek T, Giachelli CM, Alpers CE, Schwartz SM. Platelet-derived growth factor-A mRNA expression in fetal, normal adult, and atherosclerotic human aortas: Analysis by competitive polymerase chain reaction Circulation. 93: 1095-1106. PMID 8653829 DOI: 10.1161/01.Cir.93.6.1095  0.321
1996 Miano JM, Firulli AB, Olson EN, Hara P, Giachelli CM, Schwartz SM. Restricted expression of homeobox genes distinguishes fetal from adult human smooth muscle cells Proceedings of the National Academy of Sciences of the United States of America. 93: 900-905. PMID 8570656 DOI: 10.1073/Pnas.93.2.900  0.339
1995 Giachelli CM, Schwartz SM, Liaw L. Molecular and cellular biology of osteopontin Potential role in cardiovascular disease. Trends in Cardiovascular Medicine. 5: 88-95. PMID 21232243 DOI: 10.1016/1050-1738(95)00005-T  0.332
1995 Thayer JM, Giachelli CM, Mirkes PE, Schwartz SM. Expression of osteopontin in the head process late in gastrulation in the rat Journal of Experimental Zoology. 272: 240-244. PMID 7790844 DOI: 10.1002/Jez.1402720309  0.394
1995 Giachelli CM, Liaw L, Murry CE, Schwartz SM, Almeida M. Osteopontin expression in cardiovascular diseases Annals of the New York Academy of Sciences. 760: 109-126. PMID 7785890 DOI: 10.1111/J.1749-6632.1995.Tb44624.X  0.372
1995 Lindner V, Giachelli CM, Schwartz SM, Reidy MA. A subpopulation of smooth muscle cells in injured rat arteries expresses platelet-derived growth factor-B chain mRNA Circulation Research. 76: 951-957. PMID 7758166 DOI: 10.1161/01.Res.76.6.951  0.338
1995 Eddy AA, Giachelli CM, McCulloch L, Liu E. Renal expression of genes that promote interstitial inflammation and fibrosis in rats with protein-overload proteinuria Kidney International. 47: 1546-1557. PMID 7643523 DOI: 10.1038/Ki.1995.218  0.338
1995 Hoshiga M, Alpers CE, Smith LL, Giachelli CM, Schwartz SM. αvβ3 integrin expression in normal and atherosclerotic artery Circulation Research. 77: 1129-1135. PMID 7586225 DOI: 10.1161/01.Res.77.6.1129  0.336
1995 Young BA, Burdmann EA, Johnson RJ, Alpers CE, Giachelli CM, Eng E, Andoh T, Bennett WM, Couser WG, Lindsley J, Duyn J. Cellular proliferation and macrophage influx precede interstitial fibrosis in cyclosporine nephrotoxicity Kidney International. 48: 439-448. PMID 7564111 DOI: 10.1038/Ki.1995.312  0.32
1995 Liaw L, Lindner V, Schwartz SM, Chambers AF, Giachelli CM. Osteopontin and β3 integrin are coordinately expressed in regenerating endothelium in vivo and stimulate Arg-Gly-Asp-dependent endothelial migration in vitro Circulation Research. 77: 665-672. PMID 7554111 DOI: 10.1161/01.Res.77.4.665  0.379
1995 Liaw L, Skinner MP, Raines EW, Ross R, Cheresh DA, Schwartz SM, Giachelli CM. The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins: Role of αvβ3 in smooth muscle cell migration to osteopontin in vitro Journal of Clinical Investigation. 95: 713-724. PMID 7532190 DOI: 10.1172/Jci117718  0.401
1994 Liaw L, Almeida M, Hart CE, Schwartz SM, Giachelli CM. Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro. Circulation Research. 74: 214-24. PMID 8293561 DOI: 10.1161/01.Res.74.2.214  0.419
1994 O'Brien ER, Garvin MR, Stewart DK, Hinohara T, Simpson JB, Schwartz SM, Giachelli CM. Osteopontin is synthesized by macrophage, smooth muscle, and endothelial cells in primary and restenotic human coronary atherosclerotic plaques. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 14: 1648-56. PMID 7918316 DOI: 10.1161/01.Atv.14.10.1648  0.386
1993 Giachelli CM, Bae N, Almeida M, Denhardt DT, Alpers CE, Schwartz SM. Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques Journal of Clinical Investigation. 92: 1686-1696. PMID 8408622 DOI: 10.1172/Jci116755  0.32
1991 Giachelli C, Bae N, Lombardi D, Majesky M, Schwartz S. Molecular cloning and characterization of 2B7, a rat mRNA which distinguishes smooth muscle cell phenotypes in vitro and is identical to osteopontin (secreted phosphoprotein I, 2aR). Biochemical and Biophysical Research Communications. 177: 867-73. PMID 1828666 DOI: 10.1016/0006-291X(91)91870-I  0.324
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