Michael W. Schwartz - Publications

Affiliations: 
University of Washington School of Medicine, Seattle, WA, United States 

212 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bentsen MA, Rausch DM, Mirzadeh Z, Muta K, Scarlett JM, Brown JM, Herranz-Pérez V, Baquero AF, Thompson J, Alonge KM, Faber CL, Kaiyala KJ, Bennett C, Pyke C, Ratner C, ... ... Schwartz MW, et al. Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission. Nature Communications. 11: 4458. PMID 32895383 DOI: 10.1038/S41467-020-17720-5  0.323
2020 ALONGE KM, MIRZADEH Z, SCARLETT J, LOGSDON A, BROWN JM, CABRALES E, CHAN CK, KAIYALA K, BENTSEN MA, BANKS WA, GUTTMAN M, WIGHT TN, MORTON GJ, SCHWARTZ MW. 1771-P: Hypothalamic Perineuronal Net Assembly Is Required for Sustained Diabetes Remission Induced by FGF1 Diabetes. 69: 1771-P. DOI: 10.2337/Db20-1771-P  0.314
2020 Alonge KM, Mirzadeh Z, Scarlett JM, Brown JM, Bentsen MA, Logsdon AF, Banks WA, Guttman M, Wight TN, Morton GJ, Schwartz MW. Assembly of Hypothalamic Perineuronal Nets Contributes to Sustained Blood Glucose Lowering by FGF1 Action in the Brain The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05961  0.303
2019 Tateya S, Rizzo-De Leon N, Cheng AM, Dick BP, Lee WJ, Kim ML, O'Brien K, Morton GJ, Schwartz MW, Kim F. The role of vasodilator-stimulated phosphoprotein (VASP) in the control of hepatic gluconeogenic gene expression. Plos One. 14: e0215601. PMID 31017943 DOI: 10.1371/Journal.Pone.0215601  0.314
2019 Hultman K, Scarlett JM, Baquero AF, Cornea A, Zhang Y, Salinas CBG, Brown J, Morton GJ, Whalen EJ, Grove KL, Koegler FH, Schwartz MW, Mercer AJ. The central fibroblast growth factor receptor/beta klotho system: comprehensive mapping in mus musculus and comparisons to non-human primate and human samples using an automated in situ hybridization platform. The Journal of Comparative Neurology. PMID 30809795 DOI: 10.1002/Cne.24668  0.357
2019 Brown JM, Scarlett JM, Matsen ME, Nguyen HT, Secher A, Jorgensen R, Morton GJ, Schwartz MW. The Hypothalamic Arcuate Nucleus-Median Eminence is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1. Diabetes. PMID 30796029 DOI: 10.2337/Db19-0025  0.366
2019 Muta K, Matsen ME, Acharya NK, Stefanovski D, Bergman RN, Schwartz MW, Morton GJ. Glucoregulatory responses to hypothalamic preoptic area cooling. Brain Research. PMID 30610874 DOI: 10.1016/J.Brainres.2019.01.002  0.39
2018 Scarlett JM, Muta K, Brown JM, Rojas JM, Matsen ME, Acharya NK, Secher A, Ingvorsen C, Jorgensen R, Høeg-Jensen T, Stefanovski D, Bergman RN, Piccinini F, Kaiyala KJ, Shiota M, ... ... Schwartz MW, et al. Peripheral Mechanisms Mediating the Sustained Anti-Diabetic Action of FGF1 in the Brain. Diabetes. PMID 30523024 DOI: 10.2337/Db18-0498  0.375
2017 Schwartz MW, Seeley RJ, Zeltser LM, Drewnowski A, Ravussin E, Redman LM, Leibel RL. Obesity Pathogenesis: An Endocrine Society Scientific Statement. Endocrine Reviews. 38: 267-296. PMID 28898979 DOI: 10.1210/Er.2017-00111  0.354
2017 Roberts ZS, Wolden-Hanson TH, Matsen ME, Ryu V, Vaughan CH, Graham JL, Havel PJ, Chukri DW, Schwartz MW, Morton GJ, Blevins JE. Chronic Hindbrain Administration of Oxytocin is Sufficient to Elicit Weight Loss in Diet-Induced Obese Rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00169.2017. PMID 28747407 DOI: 10.1152/Ajpregu.00169.2017  0.434
2017 Campos CA, Bowen AJ, Han S, Wisse BE, Palmiter RD, Schwartz MW. Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus. Nature Neuroscience. PMID 28581479 DOI: 10.1038/Nn.4574  0.34
2017 Morton GJ, Muta K, Kaiyala KJ, Rojas JM, Scarlett JM, Matsen ME, Nelson JT, Acharya NK, Piccinini F, Stefanovski D, Bergman RN, Taborsky GJ, Kahn SE, Schwartz MW. Evidence that the Sympathetic Nervous System Elicits Rapid, Coordinated and Reciprocal Adjustments of Insulin Secretion and Insulin Sensitivity During Cold Exposure. Diabetes. PMID 28115396 DOI: 10.2337/Db16-1351  0.382
2017 Dorfman MD, Krull JE, Scarlett JM, Guyenet SJ, Sajan MP, Damian V, Nguyen HT, Leitges M, Morton GJ, Farese RV, Schwartz MW, Thaler JP. Deletion of Protein Kinase C Lambda in POMC Neurons Predisposes to Diet-Induced Obesity. Diabetes. PMID 28073831 DOI: 10.2337/Db16-0482  0.475
2016 Scarlett JM, Rojas JM, Matsen ME, Kaiyala KJ, Stefanovski D, Bergman RN, Nguyen HT, Dorfman MD, Lantier L, Wasserman DH, Mirzadeh Z, Unterman TG, Morton GJ, Schwartz MW. Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents. Nature Medicine. PMID 27213816 DOI: 10.1038/Nm.4101  0.339
2016 Campos CA, Bowen AJ, Schwartz MW, Palmiter RD. Parabrachial CGRP Neurons Control Meal Termination. Cell Metabolism. 23: 811-20. PMID 27166945 DOI: 10.1016/J.Cmet.2016.04.006  0.364
2016 Meek TH, Nelson JT, Matsen ME, Dorfman MD, Guyenet SJ, Damian V, Allison MB, Scarlett JM, Nguyen HT, Thaler JP, Olson DP, Myers MG, Schwartz MW, Morton GJ. Functional identification of a neurocircuit regulating blood glucose. Proceedings of the National Academy of Sciences of the United States of America. PMID 27001850 DOI: 10.1073/Pnas.1521160113  0.369
2016 Blevins JE, Thompson BW, Anekonda VT, Ho JM, Graham JL, Roberts ZS, Hwang BH, Ogimoto K, Wolden-Hanson TH, Nelson J, Kaiyala KJ, Havel PJ, Bales KL, Morton GJ, Schwartz MW, et al. Chronic CNS Oxytocin Signaling Preferentially Induces Fat Loss in High Fat Diet-Fed Rats by Enhancing Satiety Responses and Increasing Lipid Utilization. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00220.2015. PMID 26791828 DOI: 10.1152/Ajpregu.00220.2015  0.619
2015 Schur EA, Melhorn SJ, Oh SK, Lacy JM, Berkseth KE, Guyenet SJ, Sonnen JA, Tyagi V, Rosalynn M, De Leon B, Webb MF, Gonsalves ZT, Fligner CL, Schwartz MW, Maravilla KR. Radiologic evidence that hypothalamic gliosis is associated with obesity and insulin resistance in humans. Obesity (Silver Spring, Md.). 23: 2142-8. PMID 26530930 DOI: 10.1002/Oby.21248  0.347
2015 Morton GJ, Meek TH, Matsen ME, Schwartz MW. Evidence against hypothalamic-pituitary-adrenal axis suppression in the antidiabetic action of leptin. The Journal of Clinical Investigation. 2015. PMID 26529250 DOI: 10.1172/Jci82723  0.393
2015 Rojas JM, Matsen ME, Mundinger TO, Morton GJ, Stefanovski D, Bergman RN, Kaiyala KJ, Taborsky GJ, Schwartz MW. Glucose intolerance induced by blockade of central FGF receptors is linked to an acute stress response. Molecular Metabolism. 4: 561-8. PMID 26266088 DOI: 10.1016/J.Molmet.2015.05.005  0.382
2015 O-Sullivan I, Zhang W, Wasserman DH, Liew CW, Liu J, Paik J, DePinho RA, Stolz DB, Kahn CR, Schwartz MW, Unterman TG. Erratum: FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization. Nature Communications. 6: 7861. PMID 26206703 DOI: 10.1038/Ncomms8861  0.309
2015 O-Sullivan I, Zhang W, Wasserman DH, Liew CW, Liu J, Paik J, DePinho RA, Stolz DB, Kahn CR, Schwartz MW, Unterman TG. FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization. Nature Communications. 6: 7079. PMID 25963540 DOI: 10.1038/Ncomms8079  0.361
2015 Chen J, Kaiyala KJ, Lam J, Agrawal N, Nguyen L, Ogimoto K, Spencer D, Morton GJ, Schwartz MW, Dichek HL. In vivo structure-function studies of human hepatic lipase: the catalytic function rescues the lean phenotype of HL-deficient (hl-/-) mice. Physiological Reports. 3. PMID 25862097 DOI: 10.14814/Phy2.12365  0.346
2015 Lee WJ, Tateya S, Cheng AM, Rizzo-DeLeon N, Wang NF, Handa P, Wilson CL, Clowes AW, Sweet IR, Bomsztyk K, Schwartz MW, Kim F. M2 Macrophage Polarization Mediates Anti-inflammatory Effects of Endothelial Nitric Oxide Signaling. Diabetes. PMID 25845662 DOI: 10.2337/Db14-1668  0.322
2015 Kaiyala KJ, Ogimoto K, Nelson JT, Schwartz MW, Morton GJ. Leptin signaling is required for adaptive changes in food intake, but not energy expenditure, in response to different thermal conditions. Plos One. 10: e0119391. PMID 25756181 DOI: 10.1371/Journal.Pone.0119391  0.354
2015 Scarlett JM, Schwartz MW. Gut-brain mechanisms controlling glucose homeostasis. F1000prime Reports. 7: 12. PMID 25705395 DOI: 10.12703/P7-12  0.366
2015 Schwartz MW. Can the history of modern endocrinology shape the future of obesity? Molecular Endocrinology (Baltimore, Md.). 29: 155-7. PMID 25629595 DOI: 10.1210/Me.2014-1399  0.33
2015 Blevins JE, Graham JL, Morton GJ, Bales KL, Schwartz MW, Baskin DG, Havel PJ. Chronic oxytocin administration inhibits food intake, increases energy expenditure, and produces weight loss in fructose-fed obese rhesus monkeys. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 308: R431-8. PMID 25540103 DOI: 10.1152/Ajpregu.00441.2014  0.618
2014 van Praag H, Fleshner M, Schwartz MW, Mattson MP. Exercise, energy intake, glucose homeostasis, and the brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15139-49. PMID 25392482 DOI: 10.1523/Jneurosci.2814-14.2014  0.313
2014 Rojas JM, Schwartz MW. Control of hepatic glucose metabolism by islet and brain. Diabetes, Obesity & Metabolism. 16: 33-40. PMID 25200294 DOI: 10.1111/Dom.12332  0.386
2014 Laeger T, Henagan TM, Albarado DC, Redman LM, Bray GA, Noland RC, Münzberg H, Hutson SM, Gettys TW, Schwartz MW, Morrison CD. FGF21 is an endocrine signal of protein restriction. The Journal of Clinical Investigation. 124: 3913-22. PMID 25133427 DOI: 10.1172/Jci74915  0.347
2014 Cheng AM, Rizzo-DeLeon N, Wilson CL, Lee WJ, Tateya S, Clowes AW, Schwartz MW, Kim F. Vasodilator-stimulated phosphoprotein protects against vascular inflammation and insulin resistance. American Journal of Physiology. Endocrinology and Metabolism. 307: E571-9. PMID 25117404 DOI: 10.1152/Ajpendo.00303.2014  0.38
2014 Spiezio SH, Amon LM, McMillen TS, Vick CM, Houston BA, Caldwell M, Ogimoto K, Morton GJ, Kirk EA, Schwartz MW, Nadeau JH, LeBoeuf RC. Genetic determinants of atherosclerosis, obesity, and energy balance in consomic mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 25: 549-63. PMID 25001233 DOI: 10.1007/S00335-014-9530-2  0.336
2014 Berkseth KE, Guyenet SJ, Melhorn SJ, Lee D, Thaler JP, Schur EA, Schwartz MW. Hypothalamic gliosis associated with high-fat diet feeding is reversible in mice: a combined immunohistochemical and magnetic resonance imaging study. Endocrinology. 155: 2858-67. PMID 24914942 DOI: 10.1210/En.2014-1121  0.389
2014 Ho JM, Anekonda VT, Thompson BW, Zhu M, Curry RW, Hwang BH, Morton GJ, Schwartz MW, Baskin DG, Appleyard SM, Blevins JE. Hindbrain oxytocin receptors contribute to the effects of circulating oxytocin on food intake in male rats. Endocrinology. 155: 2845-57. PMID 24877632 DOI: 10.1210/En.2014-1148  0.651
2014 Gao Y, Ottaway N, Schriever SC, Legutko B, García-Cáceres C, de la Fuente E, Mergen C, Bour S, Thaler JP, Seeley RJ, Filosa J, Stern JE, Perez-Tilve D, Schwartz MW, Tschöp MH, et al. Hormones and diet, but not body weight, control hypothalamic microglial activity. Glia. 62: 17-25. PMID 24166765 DOI: 10.1002/Glia.22580  0.371
2013 Schwartz MW, Seeley RJ, Tschöp MH, Woods SC, Morton GJ, Myers MG, D'Alessio D. Cooperation between brain and islet in glucose homeostasis and diabetes. Nature. 503: 59-66. PMID 24201279 DOI: 10.1038/Nature12709  0.345
2013 Guyenet SJ, Matsen ME, Morton GJ, Kaiyala KJ, Schwartz MW. Rapid glutamate release in the mediobasal hypothalamus accompanies feeding and is exaggerated by an obesogenic food. Molecular Metabolism. 2: 116-22. PMID 24199157 DOI: 10.1016/J.Molmet.2013.02.001  0.343
2013 Morton GJ, Matsen ME, Bracy DP, Meek TH, Nguyen HT, Stefanovski D, Bergman RN, Wasserman DH, Schwartz MW. FGF19 action in the brain induces insulin-independent glucose lowering. The Journal of Clinical Investigation. 123: 4799-808. PMID 24084738 DOI: 10.1172/Jci70710  0.366
2013 Thaler JP, Guyenet SJ, Dorfman MD, Wisse BE, Schwartz MW. Hypothalamic inflammation: marker or mechanism of obesity pathogenesis? Diabetes. 62: 2629-34. PMID 23881189 DOI: 10.2337/Db12-1605  0.383
2013 Schwartz MW, Baskin DG. Leptin and the brain: then and now. The Journal of Clinical Investigation. 123: 2344-5. PMID 23722910 DOI: 10.1172/Jci69346  0.618
2013 Lee D, Thaler JP, Berkseth KE, Melhorn SJ, Schwartz MW, Schur EA. Longer T(2) relaxation time is a marker of hypothalamic gliosis in mice with diet-induced obesity. American Journal of Physiology. Endocrinology and Metabolism. 304: E1245-50. PMID 23548614 DOI: 10.1152/Ajpendo.00020.2013  0.33
2013 Guyenet SJ, Nguyen HT, Hwang BH, Schwartz MW, Baskin DG, Thaler JP. High-fat diet feeding causes rapid, non-apoptotic cleavage of caspase-3 in astrocytes. Brain Research. 1512: 97-105. PMID 23548599 DOI: 10.1016/J.Brainres.2013.03.033  0.6
2013 Lu M, Sarruf DA, Li P, Osborn O, Sanchez-Alavez M, Talukdar S, Chen A, Bandyopadhyay G, Xu J, Morinaga H, Dines K, Watkins S, Kaiyala K, Schwartz MW, Olefsky JM. Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues. The Journal of Biological Chemistry. 288: 10722-35. PMID 23457303 DOI: 10.1074/Jbc.M112.443606  0.421
2013 Matsen ME, Thaler JP, Wisse BE, Guyenet SJ, Meek TH, Ogimoto K, Cubelo A, Fischer JD, Kaiyala KJ, Schwartz MW, Morton GJ. In uncontrolled diabetes, thyroid hormone and sympathetic activators induce thermogenesis without increasing glucose uptake in brown adipose tissue. American Journal of Physiology. Endocrinology and Metabolism. 304: E734-46. PMID 23384771 DOI: 10.1152/Ajpendo.00488.2012  0.351
2013 Meek TH, Wisse BE, Thaler JP, Guyenet SJ, Matsen ME, Fischer JD, Taborsky GJ, Schwartz MW, Morton GJ. BDNF action in the brain attenuates diabetic hyperglycemia via insulin-independent inhibition of hepatic glucose production. Diabetes. 62: 1512-8. PMID 23274899 DOI: 10.2337/Db12-0837  0.39
2012 Mehta S, Melhorn SJ, Smeraglio A, Tyagi V, Grabowski T, Schwartz MW, Schur EA. Regional brain response to visual food cues is a marker of satiety that predicts food choice. The American Journal of Clinical Nutrition. 96: 989-99. PMID 22990034 DOI: 10.3945/Ajcn.112.042341  0.353
2012 Benzler J, Ganjam GK, Krüger M, Pinkenburg O, Kutschke M, Stöhr S, Steger J, Koch CE, Ölkrug R, Schwartz MW, Shepherd PR, Grattan DR, Tups A. Hypothalamic glycogen synthase kinase 3β has a central role in the regulation of food intake and glucose metabolism. The Biochemical Journal. 447: 175-84. PMID 22849606 DOI: 10.1042/Bj20120834  0.436
2012 Buchner DA, Geisinger JM, Glazebrook PA, Morgan MG, Spiezio SH, Kaiyala KJ, Schwartz MW, Sakurai T, Furley AJ, Kunze DL, Croniger CM, Nadeau JH. The juxtaparanodal proteins CNTNAP2 and TAG1 regulate diet-induced obesity. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 431-42. PMID 22752552 DOI: 10.1007/S00335-012-9400-8  0.364
2012 Guyenet SJ, Schwartz MW. Clinical review: Regulation of food intake, energy balance, and body fat mass: implications for the pathogenesis and treatment of obesity. The Journal of Clinical Endocrinology and Metabolism. 97: 745-55. PMID 22238401 DOI: 10.1210/Jc.2011-2525  0.407
2012 Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO, Zhao X, Sarruf DA, Izgur V, Maravilla KR, Nguyen HT, Fischer JD, Matsen ME, Wisse BE, Morton GJ, ... ... Schwartz MW, et al. Obesity is associated with hypothalamic injury in rodents and humans. The Journal of Clinical Investigation. 122: 153-62. PMID 22201683 DOI: 10.1172/Jci59660  0.624
2012 Morton GJ, Thatcher BS, Reidelberger RD, Ogimoto K, Wolden-Hanson T, Baskin DG, Schwartz MW, Blevins JE. Peripheral oxytocin suppresses food intake and causes weight loss in diet-induced obese rats. American Journal of Physiology. Endocrinology and Metabolism. 302: E134-44. PMID 22008455 DOI: 10.1152/Ajpendo.00296.2011  0.659
2012 Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO, Zhao X, Sarruf DA, Izgur V, Maravilla KR, Nguyen HT, Fischer JD, Matsen ME, Wisse BE, Morton GJ, ... ... Schwartz MW, et al. Obesity is associated with hypothalamic injury in rodents and humans (The Journal of Clinical Investigation (2012) 122, 1, (153-162) DOI: 10.1172/JCI59660) Journal of Clinical Investigation. 122: 778. DOI: 10.1172/Jci62813  0.54
2011 Tateya S, Rizzo NO, Handa P, Cheng AM, Morgan-Stevenson V, Daum G, Clowes AW, Morton GJ, Schwartz MW, Kim F. Endothelial NO/cGMP/VASP signaling attenuates Kupffer cell activation and hepatic insulin resistance induced by high-fat feeding. Diabetes. 60: 2792-801. PMID 21911751 DOI: 10.2337/Db11-0255  0.381
2011 Handa P, Tateya S, Rizzo NO, Cheng AM, Morgan-Stevenson V, Han CY, Clowes AW, Daum G, O'Brien KD, Schwartz MW, Chait A, Kim F. Reduced vascular nitric oxide-cGMP signaling contributes to adipose tissue inflammation during high-fat feeding. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2827-35. PMID 21903940 DOI: 10.1161/Atvbaha.111.236554  0.354
2011 Diano S, Liu ZW, Jeong JK, Dietrich MO, Ruan HB, Kim E, Suyama S, Kelly K, Gyengesi E, Arbiser JL, Belsham DD, Sarruf DA, Schwartz MW, Bennett AM, Shanabrough M, et al. Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity. Nature Medicine. 17: 1121-7. PMID 21873987 DOI: 10.1038/Nm.2421  0.427
2011 Williams DL, Schwartz MW. Neuroanatomy of body weight control: lessons learned from leptin. The Journal of Clinical Investigation. 121: 2152-5. PMID 21606602 DOI: 10.1172/Jci58027  0.609
2011 Eckel RH, Kahn SE, Ferrannini E, Goldfine AB, Nathan DM, Schwartz MW, Smith RJ, Smith SR. Obesity and type 2 diabetes: what can be unified and what needs to be individualized? The Journal of Clinical Endocrinology and Metabolism. 96: 1654-63. PMID 21602457 DOI: 10.1210/Jc.2011-0585  0.301
2011 Eckel RH, Kahn SE, Ferrannini E, Goldfine AB, Nathan DM, Schwartz MW, Smith RJ, Smith SR. Obesity and type 2 diabetes: what can be unified and what needs to be individualized? Diabetes Care. 34: 1424-30. PMID 21602431 DOI: 10.2337/Dc11-0447  0.301
2011 Lu M, Sarruf DA, Talukdar S, Sharma S, Li P, Bandyopadhyay G, Nalbandian S, Fan W, Gayen JR, Mahata SK, Webster NJ, Schwartz MW, Olefsky JM. Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nature Medicine. 17: 618-22. PMID 21532596 DOI: 10.1038/Nm.2332  0.45
2011 Morton GJ, Kaiyala KJ, Fisher JD, Ogimoto K, Schwartz MW, Wisse BE. Identification of a physiological role for leptin in the regulation of ambulatory activity and wheel running in mice. American Journal of Physiology. Endocrinology and Metabolism. 300: E392-401. PMID 21062956 DOI: 10.1152/Ajpendo.00546.2010  0.327
2010 Koch C, Augustine RA, Steger J, Ganjam GK, Benzler J, Pracht C, Lowe C, Schwartz MW, Shepherd PR, Anderson GM, Grattan DR, Tups A. Leptin rapidly improves glucose homeostasis in obese mice by increasing hypothalamic insulin sensitivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16180-7. PMID 21123564 DOI: 10.1523/Jneurosci.3202-10.2010  0.424
2010 Schwartz MW, Guyenet SJ, Cirulli V. The hypothalamus and ß-cell connection in the gene-targeting era. Diabetes. 59: 2991-3. PMID 21115781 DOI: 10.2337/Db10-1149  0.359
2010 Myers MG, Leibel RL, Seeley RJ, Schwartz MW. Obesity and leptin resistance: distinguishing cause from effect. Trends in Endocrinology and Metabolism: Tem. 21: 643-51. PMID 20846876 DOI: 10.1016/J.Tem.2010.08.002  0.387
2010 Ellacott KL, Morton GJ, Woods SC, Tso P, Schwartz MW. Assessment of feeding behavior in laboratory mice. Cell Metabolism. 12: 10-7. PMID 20620991 DOI: 10.1016/J.Cmet.2010.06.001  0.306
2010 Baskin DG, Kim F, Gelling RW, Russell BJ, Schwartz MW, Morton GJ, Simhan HN, Moralejo DH, Blevins JE. A new oxytocin-saporin cytotoxin for lesioning oxytocin-receptive neurons in the rat hindbrain. Endocrinology. 151: 4207-13. PMID 20610562 DOI: 10.1210/En.2010-0295  0.637
2010 Thaler JP, Schwartz MW. Minireview: Inflammation and obesity pathogenesis: the hypothalamus heats up. Endocrinology. 151: 4109-15. PMID 20573720 DOI: 10.1210/En.2010-0336  0.402
2010 German JP, Wisse BE, Thaler JP, Oh-I S, Sarruf DA, Ogimoto K, Kaiyala KJ, Fischer JD, Matsen ME, Taborsky GJ, Schwartz MW, Morton GJ. Leptin deficiency causes insulin resistance induced by uncontrolled diabetes. Diabetes. 59: 1626-34. PMID 20424233 DOI: 10.2337/Db09-1918  0.468
2010 Sarruf DA, Thaler JP, Morton GJ, German J, Fischer JD, Ogimoto K, Schwartz MW. Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats. Diabetes. 59: 1817-24. PMID 20357365 DOI: 10.2337/Db09-1878  0.471
2010 Thaler JP, Schwartz MW. Inflammation and Obesity Pathogenesis: The Hypothalamus Heats Up Endocrine Reviews. 31: 600-600. DOI: 10.1210/Edrv.31.4.9998  0.42
2009 Thaler JP, Choi SJ, Sajan MP, Ogimoto K, Nguyen HT, Matsen M, Benoit SC, Wisse BE, Farese RV, Schwartz MW. Atypical protein kinase C activity in the hypothalamus is required for lipopolysaccharide-mediated sickness responses. Endocrinology. 150: 5362-72. PMID 19819945 DOI: 10.1210/En.2009-0509  0.425
2009 Williams DL, Baskin DG, Schwartz MW. Hindbrain leptin receptor stimulation enhances the anorexic response to cholecystokinin. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 297: R1238-46. PMID 19726710 DOI: 10.1152/Ajpregu.00182.2009  0.727
2009 German J, Kim F, Schwartz GJ, Havel PJ, Rhodes CJ, Schwartz MW, Morton GJ. Hypothalamic leptin signaling regulates hepatic insulin sensitivity via a neurocircuit involving the vagus nerve. Endocrinology. 150: 4502-11. PMID 19574396 DOI: 10.1210/En.2009-0445  0.412
2009 Pamir N, McMillen TS, Kaiyala KJ, Schwartz MW, LeBoeuf RC. Receptors for tumor necrosis factor-alpha play a protective role against obesity and alter adipose tissue macrophage status. Endocrinology. 150: 4124-34. PMID 19477937 DOI: 10.1210/En.2009-0137  0.41
2009 Schur EA, Kleinhans NM, Goldberg J, Buchwald D, Schwartz MW, Maravilla K. Activation in brain energy regulation and reward centers by food cues varies with choice of visual stimulus. International Journal of Obesity (2005). 33: 653-61. PMID 19365394 DOI: 10.1038/Ijo.2009.56  0.393
2009 Sweet IR, Gilbert M, Maloney E, Hockenbery DM, Schwartz MW, Kim F. Endothelial inflammation induced by excess glucose is associated with cytosolic glucose 6-phosphate but not increased mitochondrial respiration. Diabetologia. 52: 921-31. PMID 19219423 DOI: 10.1007/S00125-009-1272-4  0.315
2009 Posey KA, Clegg DJ, Printz RL, Byun J, Morton GJ, Vivekanandan-Giri A, Pennathur S, Baskin DG, Heinecke JW, Woods SC, Schwartz MW, Niswender KD. Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet. American Journal of Physiology. Endocrinology and Metabolism. 296: E1003-12. PMID 19116375 DOI: 10.1152/Ajpendo.90377.2008  0.659
2009 Blevins JE, Morton GJ, Williams DL, Caldwell DW, Bastian LS, Wisse BE, Schwartz MW, Baskin DG. Forebrain melanocortin signaling enhances the hindbrain satiety response to CCK-8. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R476-84. PMID 19109369 DOI: 10.1152/Ajpregu.90544.2008  0.727
2009 Williams DL, Baskin DG, Schwartz MW. Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety. Endocrinology. 150: 1680-7. PMID 19074583 DOI: 10.1210/En.2008-1045  0.677
2009 Sarruf DA, Yu F, Nguyen HT, Williams DL, Printz RL, Niswender KD, Schwartz MW. Expression of peroxisome proliferator-activated receptor-gamma in key neuronal subsets regulating glucose metabolism and energy homeostasis. Endocrinology. 150: 707-12. PMID 18845632 DOI: 10.1210/En.2008-0899  0.589
2009 Baskin DG, White MF, Schwartz MW. P-2: Insulin and food intake increase neuronal phosphotyrosine levels in the arcuate nucleus of the rat hypothalamus Experimental and Clinical Endocrinology & Diabetes. 104: 66-67. DOI: 10.1055/S-0029-1211545  0.662
2009 Williams D, Schwartz M, Wisse B. The role of plasma leptin in the response to and recovery from a 24-h fast Appetite. 52: 865. DOI: 10.1016/J.Appet.2009.04.209  0.481
2009 Blevins J, Schwartz M, Russell B, Baskin D. Neurotoxic lesioning of oxytocin-sensing hindbrain neurons attenuates the satiety response to CCK-8 Appetite. 52: 820. DOI: 10.1016/J.Appet.2009.04.025  0.556
2008 Akesson L, Gelling RW, Jensen R, Ogimoto K, Fuller JM, Pefley R, Manavi S, Lernmark A, Schwartz MW. Increased lipid oxidation heralds diabetes onset in DR.lyp/lyp rats. Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association. 116: 475-80. PMID 18465680 DOI: 10.1055/S-2008-1062713  0.318
2008 Williams DL, Schwartz MW, Bastian LS, Blevins JE, Baskin DG. Immunocytochemistry and laser capture microdissection for real-time quantitative PCR identify hindbrain neurons activated by interaction between leptin and cholecystokinin. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 56: 285-93. PMID 18040081 DOI: 10.1369/Jhc.7A7331.2007  0.694
2008 Blevins JE, Morton GJ, Williams DL, Schwartz MW. Histochemical approaches to understanding central regulation of food intake by melanocortin signaling The Faseb Journal. 22: 108-108. DOI: 10.1096/Fasebj.22.2_Supplement.108  0.551
2007 Wisse BE, Ogimoto K, Tang J, Harris MK, Raines EW, Schwartz MW. Evidence that lipopolysaccharide-induced anorexia depends upon central, rather than peripheral, inflammatory signals. Endocrinology. 148: 5230-7. PMID 17673516 DOI: 10.1210/En.2007-0394  0.335
2007 Kim F, Pham M, Luttrell I, Bannerman DD, Tupper J, Thaler J, Hawn TR, Raines EW, Schwartz MW. Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity. Circulation Research. 100: 1589-96. PMID 17478729 DOI: 10.1161/Circresaha.106.142851  0.42
2007 Wisse BE, Ogimoto K, Morton GJ, Williams DL, Schwartz MW. Central interleukin-1 (IL1) signaling is required for pharmacological, but not physiological, effects of leptin on energy balance. Brain Research. 1144: 101-6. PMID 17320056 DOI: 10.1016/J.Brainres.2007.01.073  0.548
2007 Williams D, Baskin D, Schwartz M. The role of intestinal glucagon-like peptide 1 in satiety. Appetite. 49: 340. DOI: 10.1016/J.Appet.2007.03.216  0.691
2006 Williams DL, Baskin DG, Schwartz MW. Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation. Diabetes. 55: 3387-93. PMID 17130484 DOI: 10.2337/Db06-0558  0.733
2006 Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW. Central nervous system control of food intake and body weight. Nature. 443: 289-95. PMID 16988703 DOI: 10.1038/Nature05026  0.621
2006 Pardini AW, Nguyen HT, Figlewicz DP, Baskin DG, Williams DL, Kim F, Schwartz MW. Distribution of insulin receptor substrate-2 in brain areas involved in energy homeostasis. Brain Research. 1112: 169-78. PMID 16925984 DOI: 10.1016/J.Brainres.2006.06.109  0.716
2006 Kaelin CB, Gong L, Xu AW, Yao F, Hockman K, Morton GJ, Schwartz MW, Barsh GS, MacKenzie RG. Signal transducer and activator of transcription (stat) binding sites but not stat3 are required for fasting-induced transcription of agouti-related protein messenger ribonucleic acid. Molecular Endocrinology (Baltimore, Md.). 20: 2591-602. PMID 16709597 DOI: 10.1210/Me.2006-0107  0.359
2006 Gelling RW, Morton GJ, Morrison CD, Niswender KD, Myers MG, Rhodes CJ, Schwartz MW. Insulin action in the brain contributes to glucose lowering during insulin treatment of diabetes. Cell Metabolism. 3: 67-73. PMID 16399506 DOI: 10.1016/J.Cmet.2005.11.013  0.403
2006 Pardini AW, Williams DL, Baskin DG, Schwartz MW. 147 LOCALIZATION OF INSULIN RECEPTOR SUBSTRATE 2 IN BRAIN AREAS IMPORTANT FOR ENERGY HOMEOSTASIS. Journal of Investigative Medicine. 54: S105.3-S105. DOI: 10.2310/6650.2005.X0004.146  0.711
2006 Baskin DG, Williams DL, Schwartz MW. WITHDRAWN: Leptin enhances and fasting inhibits the anorexic response to Exendin-4 in the rat Appetite. DOI: 10.1016/J.Appet.2006.03.322  0.656
2005 Morton GJ, Gelling RW, Niswender KD, Morrison CD, Rhodes CJ, Schwartz MW. Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons. Cell Metabolism. 2: 411-20. PMID 16330326 DOI: 10.1016/J.Cmet.2005.10.009  0.495
2005 Xu AW, Kaelin CB, Morton GJ, Ogimoto K, Stanhope K, Graham J, Baskin DG, Havel P, Schwartz MW, Barsh GS. Effects of hypothalamic neurodegeneration on energy balance. Plos Biology. 3: e415. PMID 16296893 DOI: 10.1371/Journal.Pbio.0030415  0.6
2005 Fishel MA, Watson GS, Montine TJ, Wang Q, Green PS, Kulstad JJ, Cook DG, Peskind ER, Baker LD, Goldgaber D, Nie W, Asthana S, Plymate SR, Schwartz MW, Craft S. Hyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults. Archives of Neurology. 62: 1539-44. PMID 16216936 DOI: 10.1001/Archneur.62.10.Noc50112  0.321
2005 Williams DL, Schwartz MW. Out of synch: Clock mutation causes obesity in mice. Cell Metabolism. 1: 355-6. PMID 16054082 DOI: 10.1016/J.Cmet.2005.05.007  0.508
2005 Kim F, Tysseling KA, Rice J, Gallis B, Haji L, Giachelli CM, Raines EW, Corson MA, Schwartz MW. Activation of IKKbeta by glucose is necessary and sufficient to impair insulin signaling and nitric oxide production in endothelial cells. Journal of Molecular and Cellular Cardiology. 39: 327-34. PMID 15978611 DOI: 10.1016/J.Yjmcc.2005.05.009  0.342
2005 Williams DL, Schwartz MW. The melanocortin system as a central integrator of direct and indirect controls of food intake. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 289: R2-3. PMID 15956761 DOI: 10.1152/Ajpregu.00226.2005  0.543
2005 Sindelar DK, Palmiter RD, Woods SC, Schwartz MW. Attenuated feeding responses to circadian and palatability cues in mice lacking neuropeptide Y. Peptides. 26: 2597-602. PMID 15923061 DOI: 10.1016/J.Peptides.2005.04.018  0.387
2005 Trevaskis J, Walder K, Foletta V, Kerr-Bayles L, McMillan J, Cooper A, Lee S, Bolton K, Prior M, Fahey R, Whitecross K, Morton GJ, Schwartz MW, Collier GR. Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1, a novel neuronal protein that regulates energy balance. Endocrinology. 146: 3757-64. PMID 15919751 DOI: 10.1210/En.2005-0282  0.424
2005 Porte D, Baskin DG, Schwartz MW. Insulin signaling in the central nervous system: a critical role in metabolic homeostasis and disease from C. elegans to humans. Diabetes. 54: 1264-76. PMID 15855309 DOI: 10.2337/Diabetes.54.5.1264  0.637
2005 Xu AW, Kaelin CB, Takeda K, Akira S, Schwartz MW, Barsh GS. PI3K integrates the action of insulin and leptin on hypothalamic neurons. The Journal of Clinical Investigation. 115: 951-8. PMID 15761497 DOI: 10.1172/Jci24301  0.427
2005 Morton GJ, Blevins JE, Williams DL, Niswender KD, Gelling RW, Rhodes CJ, Baskin DG, Schwartz MW. Leptin action in the forebrain regulates the hindbrain response to satiety signals. The Journal of Clinical Investigation. 115: 703-10. PMID 15711637 DOI: 10.1172/Jci200522081  0.721
2004 Niswender KD, Baskin DG, Schwartz MW. Insulin and its evolving partnership with leptin in the hypothalamic control of energy homeostasis. Trends in Endocrinology and Metabolism: Tem. 15: 362-9. PMID 15380807 DOI: 10.1016/J.Tem.2004.07.009  0.655
2004 Wisse BE, Ogimoto K, Morton GJ, Wilkinson CW, Frayo RS, Cummings DE, Schwartz MW. Physiological regulation of hypothalamic IL-1beta gene expression by leptin and glucocorticoids: implications for energy homeostasis. American Journal of Physiology. Endocrinology and Metabolism. 287: E1107-13. PMID 15304373 DOI: 10.1152/Ajpendo.00038.2004  0.329
2004 Gelling RW, Overduin J, Morrison CD, Morton GJ, Frayo RS, Cummings DE, Schwartz MW. Effect of uncontrolled diabetes on plasma ghrelin concentrations and ghrelin-induced feeding. Endocrinology. 145: 4575-82. PMID 15256489 DOI: 10.1210/En.2004-0605  0.379
2004 Sindelar DK, Ste Marie L, Miura GI, Palmiter RD, McMinn JE, Morton GJ, Schwartz MW. Neuropeptide Y is required for hyperphagic feeding in response to neuroglucopenia. Endocrinology. 145: 3363-8. PMID 15064281 DOI: 10.1210/En.2003-1727  0.439
2004 Blevins JE, Schwartz MW, Baskin DG. Evidence that paraventricular nucleus oxytocin neurons link hypothalamic leptin action to caudal brain stem nuclei controlling meal size. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 287: R87-96. PMID 15044184 DOI: 10.1152/Ajpregu.00604.2003  0.642
2003 Blevins JE, Eakin TJ, Murphy JA, Schwartz MW, Baskin DG. Oxytocin innervation of caudal brainstem nuclei activated by cholecystokinin. Brain Research. 993: 30-41. PMID 14642828 DOI: 10.1016/J.Brainres.2003.08.036  0.636
2003 Drazen DL, Wortman MD, Schwartz MW, Clegg DJ, van Dijk G, Woods SC, Seeley RJ. Adrenalectomy alters the sensitivity of the central nervous system melanocortin system. Diabetes. 52: 2928-34. PMID 14633853 DOI: 10.2337/Diabetes.52.12.2928  0.453
2003 Wisse BE, Schwartz MW, Cummings DE. Melanocortin signaling and anorexia in chronic disease states. Annals of the New York Academy of Sciences. 994: 275-81. PMID 12851326 DOI: 10.1111/J.1749-6632.2003.Tb03190.X  0.369
2003 Watson GS, Peskind ER, Asthana S, Purganan K, Wait C, Chapman D, Schwartz MW, Plymate S, Craft S. Insulin increases CSF Abeta42 levels in normal older adults. Neurology. 60: 1899-903. PMID 12821730 DOI: 10.1212/01.Wnl.0000065916.25128.25  0.351
2003 Morton GJ, Niswender KD, Rhodes CJ, Myers MG, Blevins JE, Baskin DG, Schwartz MW. Arcuate nucleus-specific leptin receptor gene therapy attenuates the obesity phenotype of Koletsky (fa(k)/fa(k)) rats. Endocrinology. 144: 2016-24. PMID 12697710 DOI: 10.1210/En.2002-0115  0.613
2003 Woods SC, Seeley RJ, Baskin DG, Schwartz MW. Insulin and the blood-brain barrier. Current Pharmaceutical Design. 9: 795-800. PMID 12678878 DOI: 10.2174/1381612033455323  0.599
2003 Bates SH, Stearns WH, Dundon TA, Schubert M, Tso AW, Wang Y, Banks AS, Lavery HJ, Haq AK, Maratos-Flier E, Neel BG, Schwartz MW, Myers MG. STAT3 signalling is required for leptin regulation of energy balance but not reproduction. Nature. 421: 856-9. PMID 12594516 DOI: 10.1038/Nature01388  0.371
2003 Niswender KD, Gallis B, Blevins JE, Corson MA, Schwartz MW, Baskin DG. Immunocytochemical detection of phosphatidylinositol 3-kinase activation by insulin and leptin. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 51: 275-83. PMID 12588955 DOI: 10.1177/002215540305100302  0.604
2003 Schwartz MW, Woods SC, Seeley RJ, Barsh GS, Baskin DG, Leibel RL. Is the energy homeostasis system inherently biased toward weight gain? Diabetes. 52: 232-8. PMID 12540591 DOI: 10.2337/Diabetes.52.2.232  0.655
2003 Niswender KD, Morrison CD, Clegg DJ, Olson R, Baskin DG, Myers MG, Seeley RJ, Schwartz MW. Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. Diabetes. 52: 227-31. PMID 12540590 DOI: 10.2337/Diabetes.52.2.227  0.633
2003 Cummings DE, Schwartz MW. Genetics and pathophysiology of human obesity. Annual Review of Medicine. 54: 453-71. PMID 12414915 DOI: 10.1146/Annurev.Med.54.101601.152403  0.351
2002 Porte D, Baskin DG, Schwartz MW. Leptin and insulin action in the central nervous system. Nutrition Reviews. 60: S20-9; discussion S6. PMID 12403080 DOI: 10.1301/002966402320634797  0.629
2002 Barsh GS, Schwartz MW. Genetic approaches to studying energy balance: perception and integration. Nature Reviews. Genetics. 3: 589-600. PMID 12154382 DOI: 10.1038/Nrg862  0.364
2002 Blevins JE, Schwartz MW, Baskin DG. Peptide signals regulating food intake and energy homeostasis. Canadian Journal of Physiology and Pharmacology. 80: 396-406. PMID 12056545 DOI: 10.1139/Y02-035  0.667
2002 Sindelar DK, Mystkowski P, Marsh DJ, Palmiter RD, Schwartz MW. Attenuation of diabetic hyperphagia in neuropeptide Y--deficient mice. Diabetes. 51: 778-83. PMID 11872679 DOI: 10.2337/Diabetes.51.3.778  0.403
2002 Grill HJ, Schwartz MW, Kaplan JM, Foxhall JS, Breininger J, Baskin DG. Evidence that the caudal brainstem is a target for the inhibitory effect of leptin on food intake. Endocrinology. 143: 239-46. PMID 11751615 DOI: 10.1210/Endo.143.1.8589  0.739
2001 Baskin DG, Blevins JE, Schwartz MW. How the brain regulates food intake and body weight: the role of leptin. Journal of Pediatric Endocrinology & Metabolism : Jpem. 14: 1417-29. PMID 11837495  0.624
2001 Niswender KD, Morton GJ, Stearns WH, Rhodes CJ, Myers MG, Schwartz MW. Intracellular signalling. Key enzyme in leptin-induced anorexia. Nature. 413: 794-5. PMID 11677594 DOI: 10.1038/35101657  0.422
2001 Wisse BE, Frayo RS, Schwartz MW, Cummings DE. Reversal of cancer anorexia by blockade of central melanocortin receptors in rats. Endocrinology. 142: 3292-301. PMID 11459770 DOI: 10.1210/Endo.142.8.8324  0.389
2001 Adage T, Scheurink AJ, de Boer SF, de Vries K, Konsman JP, Kuipers F, Adan RA, Baskin DG, Schwartz MW, van Dijk G. Hypothalamic, metabolic, and behavioral responses to pharmacological inhibition of CNS melanocortin signaling in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3639-45. PMID 11331393 DOI: 10.1523/Jneurosci.21-10-03639.2001  0.673
2000 McMinn JE, Baskin DG, Schwartz MW. Neuroendocrine mechanisms regulating food intake and body weight. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. 1: 37-46. PMID 12119644 DOI: 10.1046/J.1467-789X.2000.00007.X  0.653
2000 McMinn JE, Sindelar DK, Havel PJ, Schwartz MW. Leptin deficiency induced by fasting impairs the satiety response to cholecystokinin. Endocrinology. 141: 4442-8. PMID 11108253 DOI: 10.1210/Endo.141.12.7815  0.439
2000 Mystkowski P, Seeley RJ, Hahn TM, Baskin DG, Havel PJ, Matsumoto AM, Wilkinson CW, Peacock-Kinzig K, Blake KA, Schwartz MW. Hypothalamic melanin-concentrating hormone and estrogen-induced weight loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8637-42. PMID 11069973 DOI: 10.1523/Jneurosci.20-22-08637.2000  0.615
2000 Baskin DG, Breininger JF, Schwartz MW. SOCS-3 expression in leptin-sensitive neurons of the hypothalamus of fed and fasted rats. Regulatory Peptides. 92: 9-15. PMID 11024559 DOI: 10.1016/S0167-0115(00)00143-9  0.638
2000 Kaiyala KJ, Prigeon RL, Kahn SE, Woods SC, Schwartz MW. Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs. Diabetes. 49: 1525-33. PMID 10969837 DOI: 10.2337/Diabetes.49.9.1525  0.43
2000 McMinn JE, Wilkinson CW, Havel PJ, Woods SC, Schwartz MW. Effect of intracerebroventricular alpha-MSH on food intake, adiposity, c-Fos induction, and neuropeptide expression. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 279: R695-703. PMID 10938261 DOI: 10.1152/Ajpregu.2000.279.2.R695  0.402
2000 Hagan MM, Rushing PA, Pritchard LM, Schwartz MW, Strack AM, Van Der Ploeg LH, Woods SC, Seeley RJ. Long-term orexigenic effects of AgRP-(83---132) involve mechanisms other than melanocortin receptor blockade. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 279: R47-52. PMID 10896863 DOI: 10.1152/Ajpregu.2000.279.1.R47  0.409
2000 Havel PJ, Hahn TM, Sindelar DK, Baskin DG, Dallman MF, Weigle DS, Schwartz MW. Effects of streptozotocin-induced diabetes and insulin treatment on the hypothalamic melanocortin system and muscle uncoupling protein 3 expression in rats. Diabetes. 49: 244-52. PMID 10868941 DOI: 10.2337/Diabetes.49.2.244  0.632
2000 Benoit S, Schwartz M, Baskin D, Woods SC, Seeley RJ. CNS melanocortin system involvement in the regulation of food intake. Hormones and Behavior. 37: 299-305. PMID 10860674 DOI: 10.1006/Hbeh.2000.1588  0.639
2000 Benoit SC, Schwartz MW, Lachey JL, Hagan MM, Rushing PA, Blake KA, Yagaloff KA, Kurylko G, Franco L, Danhoo W, Seeley RJ. A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3442-8. PMID 10777807 DOI: 10.1523/Jneurosci.20-09-03442.2000  0.427
2000 Schwartz MW, Woods SC, Porte D, Seeley RJ, Baskin DG. Central nervous system control of food intake. Nature. 404: 661-71. PMID 10766253 DOI: 10.1038/35007534  0.638
2000 Woods SC, Schwartz MW, Baskin DG, Seeley RJ. Food intake and the regulation of body weight. Annual Review of Psychology. 51: 255-77. PMID 10751972 DOI: 10.1146/Annurev.Psych.51.1.255  0.645
2000 Porte D, Seeley RJ, Woods SC, Baskin DG, Figlewicz DP, Schwartz MW. Comments on the relation among GAD-65, IA-2 antibodies and body adiposity. Diabetologia. 43: 134. PMID 10672457  0.478
2000 Craft S, Peskind E, Asthana S, Stennis Watson G, Baker LD, Cook DD, Schwartz MW. Effects of insulin on cerebrospinal fluid levels of Aβ42 Neurobiology of Aging. 21: 272. DOI: 10.1016/S0197-4580(00)83176-0  0.329
1999 van Dijk G, Seeley RJ, Thiele TE, Friedman MI, Ji H, Wilkinson CW, Burn P, Campfield LA, Tenenbaum R, Baskin DG, Woods SC, Schwartz MW. Metabolic, gastrointestinal, and CNS neuropeptide effects of brain leptin administration in the rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 276: R1425-R1433. PMID 29592687 DOI: 10.1152/ajpregu.1999.276.5.R1425  0.614
1999 Baskin DG, Figlewicz Lattemann D, Seeley RJ, Woods SC, Porte D, Schwartz MW. Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight. Brain Research. 848: 114-23. PMID 10612703 DOI: 10.1016/S0006-8993(99)01974-5  0.688
1999 Marsh DJ, Miura GI, Yagaloff KA, Schwartz MW, Barsh GS, Palmiter RD. Effects of neuropeptide Y deficiency on hypothalamic agouti-related protein expression and responsiveness to melanocortin analogues. Brain Research. 848: 66-77. PMID 10612698 DOI: 10.1016/S0006-8993(99)01962-9  0.419
1999 Kaiyala KJ, Prigeon RL, Kahn SE, Woods SC, Porte D, Schwartz MW. Reduced beta-cell function contributes to impaired glucose tolerance in dogs made obese by high-fat feeding. The American Journal of Physiology. 277: E659-67. PMID 10516125 DOI: 10.1152/Ajpendo.1999.277.4.E659  0.387
1999 Baskin DG, Hahn TM, Schwartz MW. Leptin sensitive neurons in the hypothalamus. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 31: 345-50. PMID 10422733 DOI: 10.1055/S-2007-978751  0.675
1999 Sindelar DK, Havel PJ, Seeley RJ, Wilkinson CW, Woods SC, Schwartz MW. Low plasma leptin levels contribute to diabetic hyperphagia in rats. Diabetes. 48: 1275-80. PMID 10342816 DOI: 10.2337/Diabetes.48.6.1275  0.367
1999 van Dijk G, Seeley RJ, Thiele TE, Friedman MI, Ji H, Wilkinson CW, Burn P, Campfield LA, Tenenbaum R, Baskin DG, Woods SC, Schwartz MW. Metabolic, gastrointestinal, and CNS neuropeptide effects of brain leptin administration in the rat. The American Journal of Physiology. 276: R1425-33. PMID 10233036 DOI: 10.1152/Ajpregu.1999.276.5.R1425  0.653
1999 Schwartz MW, Baskin DG, Kaiyala KJ, Woods SC. Model for the regulation of energy balance and adiposity by the central nervous system. The American Journal of Clinical Nutrition. 69: 584-96. PMID 10197558  0.567
1999 Baskin DG, Breininger JF, Schwartz MW. Leptin receptor mRNA identifies a subpopulation of neuropeptide Y neurons activated by fasting in rat hypothalamus. Diabetes. 48: 828-33. PMID 10102700 DOI: 10.2337/Diabetes.48.4.828  0.633
1999 Seeley RJ, Schwartz MW. Neuroendocrine regulation of food intake. Acta Paediatrica (Oslo, Norway : 1992). Supplement. 88: 58-61. PMID 10102053 DOI: 10.1111/J.1651-2227.1999.Tb14352.X  0.404
1999 Hagan MM, Rushing PA, Schwartz MW, Yagaloff KA, Burn P, Woods SC, Seeley RJ. Role of the CNS melanocortin system in the response to overfeeding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2362-7. PMID 10066286 DOI: 10.1523/Jneurosci.19-06-02362.1999  0.424
1999 Baskin DG, Schwartz MW, Seeley RJ, Woods SC, Porte D, Breininger JF, Jonak Z, Schaefer J, Krouse M, Burghardt C, Campfield LA, Burn P, Kochan JP. Leptin receptor long-form splice-variant protein expression in neuron cell bodies of the brain and co-localization with neuropeptide Y mRNA in the arcuate nucleus. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 47: 353-62. PMID 10026237 DOI: 10.1177/002215549904700309  0.619
1998 Thiele TE, Van Dijk G, Yagaloff KA, Fisher SL, Schwartz M, Burn P, Seeley RJ. Central infusion of melanocortin agonist MTII in rats: assessment of c-Fos expression and taste aversion. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 274: R248-R254. PMID 29592157 DOI: 10.1152/ajpregu.1998.274.1.R248  0.319
1998 Hahn TM, Breininger JF, Baskin DG, Schwartz MW. Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons. Nature Neuroscience. 1: 271-2. PMID 10195157 DOI: 10.1038/1082  0.644
1998 McMinn JE, Seeley RJ, Wilkinson CW, Havel PJ, Woods SC, Schwartz MW. NPY-induced overfeeding suppresses hypothalamic NPY mRNA expression: potential roles of plasma insulin and leptin. Regulatory Peptides. 75: 425-31. PMID 9802439 DOI: 10.1016/S0167-0115(98)00098-6  0.467
1998 Porte D, Seeley RJ, Woods SC, Baskin DG, Figlewicz DP, Schwartz MW. Obesity, diabetes and the central nervous system. Diabetologia. 41: 863-81. PMID 9726588 DOI: 10.1007/S001250051002  0.562
1998 Chavez M, Seeley RJ, Havel PJ, Friedman MI, Matson CA, Woods SC, Schwartz MW. Effect of a high-fat diet on food intake and hypothalamic neuropeptide gene expression in streptozotocin diabetes. The Journal of Clinical Investigation. 102: 340-6. PMID 9664075 DOI: 10.1172/Jci603  0.394
1998 Woods SC, Seeley RJ, Porte D, Schwartz MW. Signals that regulate food intake and energy homeostasis. Science (New York, N.Y.). 280: 1378-83. PMID 9603721 DOI: 10.1126/Science.280.5368.1378  0.373
1998 Baskin DG, Seeley RJ, Kuijper JL, Lok S, Weigle DS, Erickson JC, Palmiter RD, Schwartz MW. Increased expression of mRNA for the long form of the leptin receptor in the hypothalamus is associated with leptin hypersensitivity and fasting. Diabetes. 47: 538-43. PMID 9568684 DOI: 10.2337/Diabetes.47.4.538  0.633
1998 Schwartz MW, Erickson JC, Baskin DG, Palmiter RD. Effect of fasting and leptin deficiency on hypothalamic neuropeptide Y gene transcription in vivo revealed by expression of a lacZ reporter gene. Endocrinology. 139: 2629-35. PMID 9564880 DOI: 10.1210/Endo.139.5.6000  0.606
1998 Weigle DS, Selfridge LE, Schwartz MW, Seeley RJ, Cummings DE, Havel PJ, Kuijper JL, BeltrandelRio H. Elevated free fatty acids induce uncoupling protein 3 expression in muscle: a potential explanation for the effect of fasting. Diabetes. 47: 298-302. PMID 9519732 DOI: 10.2337/Diab.47.2.298  0.325
1998 Thiele TE, van Dijk G, Yagaloff KA, Fisher SL, Schwartz M, Burn P, Seeley RJ. Central infusion of melanocortin agonist MTII in rats: assessment of c-Fos expression and taste aversion. The American Journal of Physiology. 274: R248-54. PMID 9458925 DOI: 10.1152/Ajpregu.1998.274.1.R248  0.431
1998 Craft S, Peskind E, Schwartz MW, Schellenberg GD, Raskind M, Porte D. Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype. Neurology. 50: 164-8. PMID 9443474 DOI: 10.1212/Wnl.50.1.164  0.332
1997 Schwartz MW, Strack AM, Dallman MF. Evidence that elevated plasma corticosterone levels are the cause of reduced hypothalamic corticotrophin-releasing hormone gene expression in diabetes. Regulatory Peptides. 72: 105-12. PMID 9652969 DOI: 10.1016/S0167-0115(97)01043-4  0.334
1997 Schwartz MW, Seeley RJ, Woods SC, Weigle DS, Campfield LA, Burn P, Baskin DG. Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus. Diabetes. 46: 2119-23. PMID 9392508 DOI: 10.2337/Diab.46.12.2119  0.635
1997 Seeley RJ, Yagaloff KA, Fisher SL, Burn P, Thiele TE, van Dijk G, Baskin DG, Schwartz MW. Melanocortin receptors in leptin effects. Nature. 390: 349. PMID 9389472 DOI: 10.1038/37016  0.632
1997 Chavez M, Seeley RJ, Green PK, Wilkinson CW, Schwartz MW, Woods SC. Adrenalectomy increases sensitivity to central insulin. Physiology & Behavior. 62: 631-4. PMID 9272675 DOI: 10.1016/S0031-9384(97)00188-1  0.467
1997 Schwartz MW, Seeley RJ. Seminars in medicine of the Beth Israel Deaconess Medical Center. Neuroendocrine responses to starvation and weight loss. The New England Journal of Medicine. 336: 1802-11. PMID 9187072 DOI: 10.1056/Nejm199706193362507  0.314
1997 Schwartz MW, Seeley RJ. The new biology of body weight regulation. Journal of the American Dietetic Association. 97: 54-8; quiz 59-60. PMID 8990418 DOI: 10.1016/S0002-8223(97)00018-7  0.436
1996 Seeley RJ, van Dijk G, Campfield LA, Smith FJ, Burn P, Nelligan JA, Bell SM, Baskin DG, Woods SC, Schwartz MW. Intraventricular leptin reduces food intake and body weight of lean rats but not obese Zucker rats. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 28: 664-8. PMID 9013738 DOI: 10.1055/S-2007-979874  0.655
1996 Seeley RJ, Matson CA, Chavez M, Woods SC, Dallman MF, Schwartz MW. Behavioral, endocrine, and hypothalamic responses to involuntary overfeeding. The American Journal of Physiology. 271: R819-23. PMID 8853408 DOI: 10.1152/Ajpregu.1996.271.3.R819  0.482
1996 Schwartz MW, Seeley RJ, Campfield LA, Burn P, Baskin DG. Identification of targets of leptin action in rat hypothalamus. The Journal of Clinical Investigation. 98: 1101-6. PMID 8787671 DOI: 10.1172/Jci118891  0.68
1996 Figlewicz DP, Schwartz MW, Seeley RJ, Chavez M, Baskin DG, Woods SC, Porte D. Endocrine regulation of food intake and body weight. The Journal of Laboratory and Clinical Medicine. 127: 328-32. PMID 8656034 DOI: 10.1016/S0022-2143(96)90179-1  0.624
1996 Woods SC, Chavez M, Park CR, Riedy C, Kaiyala K, Richardson RD, Figlewicz DP, Schwartz MW, Porte D, Seeley RJ. The evaluation of insulin as a metabolic signal influencing behavior via the brain. Neuroscience and Biobehavioral Reviews. 20: 139-44. PMID 8622820 DOI: 10.1016/0149-7634(95)00044-F  0.474
1996 Schwartz MW, Baskin DG, Bukowski TR, Kuijper JL, Foster D, Lasser G, Prunkard DE, Porte D, Woods SC, Seeley RJ, Weigle DS. Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes. 45: 531-5. PMID 8603777 DOI: 10.2337/Diab.45.4.531  0.656
1995 Sipols AJ, Baskin DG, Schwartz MW. Effect of intracerebroventricular insulin infusion on diabetic hyperphagia and hypothalamic neuropeptide gene expression. Diabetes. 44: 147-51. PMID 7859932 DOI: 10.2337/Diab.44.2.147  0.637
1995 Strack AM, Sebastian RJ, Schwartz MW, Dallman MF. Glucocorticoids and insulin: reciprocal signals for energy balance. The American Journal of Physiology. 268: R142-9. PMID 7840315 DOI: 10.1152/Ajpregu.1995.268.1.R142  0.479
1995 Antonelli MC, Costa Lieste M, Baskin DG, Stahl WL, Schwartz MW. Localization of Na, K-ATPase isoforms in the hypothalamus of the rat. Cellular and Molecular Biology (Noisy-Le-Grand, France). 41: 79-85. PMID 7773139  0.488
1995 Schwartz MW, Boyko EJ, Kahn SE, Ravussin E, Bogardus C. Reduced insulin secretion: an independent predictor of body weight gain. The Journal of Clinical Endocrinology and Metabolism. 80: 1571-6. PMID 7745002 DOI: 10.1210/Jcem.80.5.7745002  0.416
1995 Chavez M, Kaiyala K, Madden LJ, Schwartz MW, Woods SC. Intraventricular insulin and the level of maintained body weight in rats. Behavioral Neuroscience. 109: 528-31. PMID 7662162 DOI: 10.1037//0735-7044.109.3.528  0.337
1995 Baskin DG, Norwood BJ, Schwartz MW, Koerker DJ. Estradiol inhibits the increase of hypothalamic neuropeptide Y messenger ribonucleic acid expression induced by weight loss in ovariectomized rats. Endocrinology. 136: 5547-54. PMID 7588307 DOI: 10.1210/Endo.136.12.7588307  0.603
1995 Schwartz MW, Dallman MF, Woods SC. Hypothalamic response to starvation: implications for the study of wasting disorders. The American Journal of Physiology. 269: R949-57. PMID 7503322 DOI: 10.1152/Ajpregu.1995.269.5.R949  0.368
1995 Kaiyala KJ, Woods SC, Schwartz MW. New model for the regulation of energy balance and adiposity by the central nervous system. The American Journal of Clinical Nutrition. 62: 1123S-1134S. PMID 7484931 DOI: 10.1093/Ajcn/62.5.1123S  0.404
1994 Verchere CB, Kowalyk S, Shen GH, Brown MR, Schwartz MW, Baskin DG, Taborsky GJ. Major species variation in the expression of galanin messenger ribonucleic acid in mammalian celiac ganglion. Endocrinology. 135: 1052-9. PMID 7520862 DOI: 10.1210/Endo.135.3.7520862  0.58
1994 Baskin DG, Schwartz MW, Sipols AJ, D'Alessio DA, Goldstein BJ, White MF. Insulin receptor substrate-1 (IRS-1) expression in rat brain. Endocrinology. 134: 1952-5. PMID 7511094 DOI: 10.1210/Endo.134.4.7511094  0.63
1993 Baskin DG, Gierke EP, Wilcox BJ, Matsumoto AM, Schwartz MW. Food intake and estradiol effects on insulin binding in brain and liver. Physiology & Behavior. 53: 757-62. PMID 8511182 DOI: 10.1016/0031-9384(93)90185-I  0.646
1993 Israel PA, Park CR, Schwartz MW, Green PK, Sipols AJ, Woods SC, Porte D, Figlewicz DP. Effect of diet-induced obesity and experimental hyperinsulinemia on insulin uptake into CSF of the rat. Brain Research Bulletin. 30: 571-5. PMID 8457906 DOI: 10.1016/0361-9230(93)90084-O  0.415
1993 Baura GD, Foster DM, Porte D, Kahn SE, Bergman RN, Cobelli C, Schwartz MW. Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain. The Journal of Clinical Investigation. 92: 1824-30. PMID 8408635 DOI: 10.1172/Jci116773  0.379
1993 Kahn SE, Prigeon RL, McCulloch DK, Boyko EJ, Bergman RN, Schwartz MW, Neifing JL, Ward WK, Beard JC, Palmer JP. Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function. Diabetes. 42: 1663-72. PMID 8405710 DOI: 10.2337/Diab.42.11.1663  0.34
1993 Schwartz MW, Figlewicz DP, Woods SC, Porte D, Baskin DG. Insulin, neuropeptide Y, and food intake. Annals of the New York Academy of Sciences. 692: 60-71. PMID 8215045 DOI: 10.1111/J.1749-6632.1993.Tb26206.X  0.635
1993 Boswell T, Richardson RD, Schwartz MW, D'Alessio DA, Woods SC, Sipols AJ, Baskin DG, Kenagy GJ. NPY and galanin in a hibernator: hypothalamic gene expression and effects on feeding. Brain Research Bulletin. 32: 379-84. PMID 7693306 DOI: 10.1016/0361-9230(93)90203-N  0.634
1993 Schwartz MW, Sipols AJ, Grubin CE, Baskin DG. Differential effect of fasting on hypothalamic expression of genes encoding neuropeptide Y, galanin, and glutamic acid decarboxylase. Brain Research Bulletin. 31: 361-7. PMID 7683962 DOI: 10.1016/0361-9230(93)90228-4  0.617
1993 Baskin DG, Sipols AJ, Schwartz MW, White MF. Immunocytochemical detection of insulin receptor substrate-1 (IRS-1) in rat brain: colocalization with phosphotyrosine. Regulatory Peptides. 48: 257-66. PMID 7505468 DOI: 10.1016/0167-0115(93)90355-C  0.629
1992 Marks JL, Li M, Schwartz M, Porte D, Baskin DG. Effect of fasting on regional levels of neuropeptide Y mRNA and insulin receptors in the rat hypothalamus: An autoradiographic study. Molecular and Cellular Neurosciences. 3: 199-205. PMID 19912861 DOI: 10.1016/1044-7431(92)90039-5  0.629
1992 Schwartz MW, Sipols AJ, Marks JL, Sanacora G, White JD, Scheurink A, Kahn SE, Baskin DG, Woods SC, Figlewicz DP. Inhibition of hypothalamic neuropeptide Y gene expression by insulin. Endocrinology. 130: 3608-16. PMID 1597158 DOI: 10.1210/Endo.130.6.1597158  0.649
1992 Kahn SE, Bergman RN, Schwartz MW, Taborsky GJ, Porte D. Short-term hyperglycemia and hyperinsulinemia improve insulin action but do not alter glucose action in normal humans. The American Journal of Physiology. 262: E518-23. PMID 1566838 DOI: 10.1152/Ajpendo.1992.262.4.E518  0.363
1992 Schwartz MW, Figlewicz DP, Baskin DG, Woods SC, Porte D. Insulin in the brain: a hormonal regulator of energy balance. Endocrine Reviews. 13: 387-414. PMID 1425482 DOI: 10.1210/Edrv-13-3-387  0.614
1991 Schwartz MW, Marks JL, Sipols AJ, Baskin DG, Woods SC, Kahn SE, Porte D. Central insulin administration reduces neuropeptide Y mRNA expression in the arcuate nucleus of food-deprived lean (Fa/Fa) but not obese (fa/fa) Zucker rats. Endocrinology. 128: 2645-7. PMID 2019270 DOI: 10.1210/Endo-128-5-2645  0.663
1991 Schwartz MW, Bergman RN, Kahn SE, Taborsky GJ, Fisher LD, Sipols AJ, Woods SC, Steil GM, Porte D. Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport. The Journal of Clinical Investigation. 88: 1272-81. PMID 1918377 DOI: 10.1172/Jci115431  0.341
1990 Kahn SE, Klaff LJ, Schwartz MW, Beard JC, Bergman RN, Taborsky GJ, Porte D. Treatment with a somatostatin analog decreases pancreatic B-cell and whole body sensitivity to glucose. The Journal of Clinical Endocrinology and Metabolism. 71: 994-1002. PMID 2205630 DOI: 10.1210/Jcem-71-4-994  0.324
1990 Schwartz MW, Sipols A, Kahn SE, Lattemann DF, Taborsky GJ, Bergman RN, Woods SC, Porte D. Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid. The American Journal of Physiology. 259: E378-83. PMID 2205107 DOI: 10.1152/Ajpendo.1990.259.3.E378  0.367
1990 Schwartz MW, Figlewicz DF, Kahn SE, Baskin DG, Greenwood MR, Porte D. Insulin binding to brain capillaries is reduced in genetically obese, hyperinsulinemic Zucker rats. Peptides. 11: 467-72. PMID 2199946 DOI: 10.1016/0196-9781(90)90044-6  0.626
1990 Saad MF, Kahn SE, Nelson RG, Pettitt DJ, Knowler WC, Schwartz MW, Kowalyk S, Bennett PH, Porte D. Disproportionately elevated proinsulin in Pima Indians with noninsulin-dependent diabetes mellitus. The Journal of Clinical Endocrinology and Metabolism. 70: 1247-53. PMID 2186054 DOI: 10.1210/Jcem-70-5-1247  0.344
1990 Kahn SE, D'Alessio DA, Schwartz MW, Fujimoto WY, Ensinck JW, Taborsky GJ, Porte D. Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells. Diabetes. 39: 634-8. PMID 2185112 DOI: 10.2337/Diab.39.5.634  0.329
1989 Kahn SE, Beard JC, Schwartz MW, Ward WK, Ding HL, Bergman RN, Taborsky GJ, Porte D. Increased beta-cell secretory capacity as mechanism for islet adaptation to nicotinic acid-induced insulin resistance. Diabetes. 38: 562-8. PMID 2653928 DOI: 10.2337/Diab.38.5.562  0.357
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