Fayez F. Safadi - Publications

Affiliations: 
Cell Biology Temple University, Philadelphia, PA, United States 
Area:
Cell Biology, Molecular Biology, Genetics

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Solorzano E, Alejo AL, Ball HC, Robinson GT, Solorzano AL, Safadi R, Douglas J, Kelly M, Safadi FF. The Lymphatic Endothelial Cell Secretome Inhibits Osteoblast Differentiation and Bone Formation. Cells. 12. PMID 37887326 DOI: 10.3390/cells12202482  0.37
2020 Cooper LN, Ball HC, Vinyard CJ, Safadi FF, George JC, Thewissen JGM. Linking gene expression and phenotypic changes in the developmental and evolutionary origins of osteosclerosis in the ribs of bowhead whales (Balaena mysticetus). Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution. PMID 32729176 DOI: 10.1002/Jez.B.22990  0.339
2020 Solorzano E, Kelly M, Safadi F. Semaphorin‐3F, a Potential Biomarker for Lymphatic Anomalies and Bone Cell Function The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09824  0.405
2019 Hussein NJ, Mbimba T, Al-Adlaan AA, Ansari MY, Jaber FA, McDermott S, Kasumov T, Safadi FF. A novel regulatory role of TRAPPC9 in L-plastin-mediated osteoclast actin ring formation. Journal of Cellular Biochemistry. PMID 31453638 DOI: 10.1002/Jcb.29168  0.386
2019 Jaber FA, Khan NM, Ansari MY, Al-Adlaan AA, Hussein NJ, Safadi FF. Autophagy plays an essential role in bone homeostasis. Journal of Cellular Physiology. PMID 30820954 DOI: 10.1002/Jcp.27071  0.427
2016 Sondag GR, Mbimba TS, Moussa FM, Novak K, Yu B, Jaber FA, Abdelmagid SM, Geldenhuys WJ, Safadi FF. Osteoactivin inhibition of osteoclastogenesis is mediated through CD44-ERK signaling. Experimental & Molecular Medicine. 48: e257. PMID 27585719 DOI: 10.1038/Emm.2016.78  0.729
2016 Ball HC, Moussa FM, Mbimba T, Orman R, Safadi FF, Cooper LN. Methods and insights from the characterization of osteoprogenitor cells of bats (Mammalia: Chiroptera). Stem Cell Research. 17: 54-61. PMID 27240251 DOI: 10.1016/J.Scr.2016.05.009  0.374
2016 Zhou X, Moussa FM, Mankoci S, Ustriyana P, Zhang N, Abdelmagid S, Molenda J, Murphy WL, Safadi FF, Sahai N. Orthosilicic acid, Si(OH)4, stimulates osteoblast differentiation in vitro by upregulating miR-146a to antagonize NF-κB activation. Acta Biomaterialia. PMID 27163405 DOI: 10.1016/J.Actbio.2016.05.007  0.685
2016 Frara N, Abdelmagid SM, Tytell M, Amin M, Popoff SN, Safadi FF, Barbe MF. Growth and repair factors, osteoactivin, matrix metalloproteinase and heat shock protein 72, increase with resolution of inflammation in musculotendinous tissues in a rat model of repetitive grasping. Bmc Musculoskeletal Disorders. 17: 34. PMID 26781840 DOI: 10.1186/S12891-016-0892-3  0.701
2016 Frara N, Abdelmagid SM, Sondag GR, Moussa FM, Yingling VR, Owen TA, Popoff SN, Barbe MF, Safadi FF. Transgenic Expression of Osteoactivin/gpnmb Enhances Bone Formation In Vivo and Osteoprogenitor Differentiation Ex Vivo. Journal of Cellular Physiology. 231: 72-83. PMID 25899717 DOI: 10.1002/Jcp.25020  0.758
2015 Wu B, Sondag G, Malcuit C, Kim MH, Safadi FF. Macrophage-Associated Osteoactivin/GPNMB Mediates Mesenchymal Stem Cell Survival, Proliferation, and Migration via a CD44-Dependent Mechanism. Journal of Cellular Biochemistry. PMID 26442636 DOI: 10.1002/Jcb.25394  0.396
2015 Abdelmagid SM, Sondag GR, Moussa FM, Belcher JY, Yu B, Stinnett H, Novak K, Mbimba T, Khol M, Hankenson KD, Malcuit C, Safadi FF. Mutation in Osteoactivin Promotes Receptor Activator of NFκB Ligand (RANKL)-mediated Osteoclast Differentiation and Survival but Inhibits Osteoclast Function. The Journal of Biological Chemistry. 290: 20128-46. PMID 25837253 DOI: 10.1074/Jbc.M114.624270  0.741
2015 Hendesi H, Barbe MF, Safadi FF, Monroy MA, Popoff SN. Integrin mediated adhesion of osteoblasts to connective tissue growth factor (CTGF/CCN2) induces cytoskeleton reorganization and cell differentiation. Plos One. 10: e0115325. PMID 25714841 DOI: 10.1371/Journal.Pone.0115325  0.372
2015 Abdelmagid SM, Barbe MF, Safadi FF. Role of inflammation in the aging bones. Life Sciences. 123: 25-34. PMID 25510309 DOI: 10.1016/J.Lfs.2014.11.011  0.71
2015 Abdelmagid SM, Sondag GR, Moussa FM, Belcher JY, Yu B, Stinnett H, Novak K, Mbimba T, Khol M, Hankenson KD, Malcuit C, Safadi FF. Mutation in osteoactivin promotes receptor activator of NFκB ligand (RANKL)-mediated osteoclast differentiation and survival but inhibits osteoclast function Journal of Biological Chemistry. 290: 20128-20146. DOI: 10.1074/jbc.M114.624270  0.682
2014 Geldenhuys WJ, Abdelmagid SM, Gallegos PJ, Safadi FF. Parkinson's disease biomarker: a patent evaluation of WO2013153386. Expert Opinion On Therapeutic Patents. 24: 947-51. PMID 24962176 DOI: 10.1517/13543776.2014.931375  0.631
2014 Abdelmagid SM, Belcher JY, Moussa FM, Lababidi SL, Sondag GR, Novak KM, Sanyurah AS, Frara NA, Razmpour R, Del Carpio-Cano FE, Safadi FF. Mutation in osteoactivin decreases bone formation in vivo and osteoblast differentiation in vitro. The American Journal of Pathology. 184: 697-713. PMID 24462663 DOI: 10.1016/j.ajpath.2013.11.031  0.757
2014 Moussa FM, Hisijara IA, Sondag GR, Scott EM, Frara N, Abdelmagid SM, Safadi FF. Osteoactivin promotes osteoblast adhesion through HSPG and αvβ1 integrin. Journal of Cellular Biochemistry. 115: 1243-53. PMID 24415158 DOI: 10.1002/jcb.24760  0.724
2014 Sondag GR, Salihoglu S, Lababidi SL, Crowder DC, Moussa FM, Abdelmagid SM, Safadi FF. Osteoactivin induces transdifferentiation of C2C12 myoblasts into osteoblasts. Journal of Cellular Physiology. 229: 955-66. PMID 24265122 DOI: 10.1002/jcp.24512  0.751
2012 Abdelmagid SM, Barr AE, Rico M, Amin M, Litvin J, Popoff SN, Safadi FF, Barbe MF. Performance of repetitive tasks induces decreased grip strength and increased fibrogenic proteins in skeletal muscle: role of force and inflammation. Plos One. 7: e38359. PMID 22675458 DOI: 10.1371/Journal.Pone.0038359  0.703
2012 Rico MC, Rough JJ, Manns JM, Del Carpio-Cano F, Safadi FF, Kunapuli SP, DeLa Cadena RA. Assembly of the prothrombinase complex on the surface of human foreskin fibroblasts: Implications for connective tissue growth factor. Thrombosis Research. 129: 801-6. PMID 21889790 DOI: 10.1016/J.Thromres.2011.08.009  0.36
2012 Singh M, Del Carpio-Cano FE, Monroy MA, Popoff SN, Safadi FF. Homeodomain transcription factors regulate BMP-2-induced osteoactivin transcription in osteoblasts. Journal of Cellular Physiology. 227: 390-9. PMID 21503878 DOI: 10.1002/Jcp.22791  0.638
2012 Ou Y, Belcher JY, Yingling VR, Safadi F, Pleshko N. Compositional and mechanical properties of long bones of osteoactivin mutant mice 2012 38th Annual Northeast Bioengineering Conference, Nebec 2012. 436-437. DOI: 10.1109/NEBC.2012.6206928  0.351
2011 Arnott JA, Lambi AG, Mundy C, Hendesi H, Pixley RA, Owen TA, Safadi FF, Popoff SN. The role of connective tissue growth factor (CTGF/CCN2) in skeletogenesis. Critical Reviews in Eukaryotic Gene Expression. 21: 43-69. PMID 21967332 DOI: 10.1615/Critreveukargeneexpr.V21.I1.40  0.507
2011 Joshi RN, Safadi FF, Barbe MF, Del Carpio-Cano F, Popoff SN, Yingling VR. Different effects on bone strength and cell differentiation in pre pubertal caloric restriction versus hypothalamic suppression. Bone. 49: 810-8. PMID 21807131 DOI: 10.1016/J.Bone.2011.07.019  0.44
2011 Arosarena OA, Del Carpio-Cano FE, Dela Cadena RA, Rico MC, Nwodim E, Safadi FF. Comparison of bone morphogenetic protein-2 and osteoactivin for mesenchymal cell differentiation: effects of bolus and continuous administration. Journal of Cellular Physiology. 226: 2943-52. PMID 21302290 DOI: 10.1002/Jcp.22639  0.493
2010 Singh M, Del Carpio-Cano F, Belcher JY, Crawford K, Frara N, Owen TA, Popoff SN, Safadi FF. Functional roles of osteoactivin in normal and disease processes. Critical Reviews in Eukaryotic Gene Expression. 20: 341-57. PMID 21395506 DOI: 10.1615/Critreveukargeneexpr.V20.I4.50  0.65
2010 Abdelmagid SM, Barbe MF, Hadjiargyrou M, Owen TA, Razmpour R, Rehman S, Popoff SN, Safadi FF. Temporal and spatial expression of osteoactivin during fracture repair. Journal of Cellular Biochemistry. 111: 295-309. PMID 20506259 DOI: 10.1002/Jcb.22702  0.735
2010 Zhang X, Arnott JA, Rehman S, Delong WG, Sanjay A, Safadi FF, Popoff SN. Src is a major signaling component for CTGF induction by TGF-beta1 in osteoblasts. Journal of Cellular Physiology. 224: 691-701. PMID 20432467 DOI: 10.1002/Jcp.22173  0.337
2009 Zhu S, Barbe MF, Liu C, Hadjiargyrou M, Popoff SN, Rani S, Safadi FF, Litvin J. Periostin-like-factor in osteogenesis. Journal of Cellular Physiology. 218: 584-92. PMID 19006175 DOI: 10.1002/Jcp.21633  0.531
2009 Safadi FF, Barbe MF, Abdelmagid SM, Rico MC, Aswad RA, Litvin J, Popoff SN. Bone structure, development and bone biology Bone Pathology. 1-50. DOI: 10.1007/978-1-59745-347-9_1  0.716
2008 Abdelmagid SM, Barbe MF, Rico MC, Salihoglu S, Arango-Hisijara I, Selim AH, Anderson MG, Owen TA, Popoff SN, Safadi FF. Osteoactivin, an anabolic factor that regulates osteoblast differentiation and function. Experimental Cell Research. 314: 2334-51. PMID 18555216 DOI: 10.1016/J.Yexcr.2008.02.006  0.767
2008 Barbe MF, Elliott MB, Abdelmagid SM, Amin M, Popoff SN, Safadi FF, Barr AE. Serum and tissue cytokines and chemokines increase with repetitive upper extremity tasks. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 26: 1320-6. PMID 18464247 DOI: 10.1002/Jor.20674  0.683
2008 Polimeni G, Koo KT, Pringle GA, Agelan A, Safadi FF, Wikesjö UM. Histopathological observations of a polylactic acid-based device intended for guided bone/tissue regeneration. Clinical Implant Dentistry and Related Research. 10: 99-105. PMID 18462206 DOI: 10.1111/J.1708-8208.2007.00067.X  0.344
2008 Arnott JA, Zhang X, Sanjay A, Owen TA, Smock SL, Rehman S, DeLong WG, Safadi FF, Popoff SN. Molecular requirements for induction of CTGF expression by TGF-beta1 in primary osteoblasts. Bone. 42: 871-85. PMID 18314002 DOI: 10.1016/J.Bone.2008.01.006  0.349
2008 Zhu S, Barbe MF, Amin N, Rani S, Popoff SN, Safadi FF, Litvin J. Immunolocalization of Periostin-like factor and Periostin during embryogenesis. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 56: 329-45. PMID 18040074 DOI: 10.1369/Jhc.7A7321.2007  0.35
2007 Selim AA, Castaneda JL, Owen TA, Popoff SN, Safadi FF. The role of osteoactivin-derived peptides in osteoblast differentiation. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 13: BR259-70. PMID 18049427  0.616
2007 Rico MC, Castaneda JL, Manns JM, Uknis AB, Sainz IM, Safadi FF, Popoff SN, Dela Cadena RA. Amelioration of inflammation, angiogenesis and CTGF expression in an arthritis model by a TSP1-derived peptide treatment. Journal of Cellular Physiology. 211: 504-12. PMID 17219411 DOI: 10.1182/Blood.V108.11.1641.1641  0.32
2007 Lin YL, de Villiers WJ, Garvy B, Post SR, Nagy TR, Safadi FF, Faugere MC, Wang G, Malluche HH, Williams JP. The effect of class a scavenger receptor deficiency in bone. The Journal of Biological Chemistry. 282: 4653-60. PMID 17166840 DOI: 10.1074/Jbc.M608552200  0.332
2007 Arnott JA, Nuclozeh E, Rico MC, Arango-Hisijara I, Odgren PR, Safadi FF, Popoff SN. Connective tissue growth factor (CTGF/CCN2) is a downstream mediator for TGF-β1-induced extracellular matrix production in osteoblasts Journal of Cellular Physiology. 210: 843-852. PMID 17133352 DOI: 10.1002/Jcp.20917  0.356
2007 Song JJ, Aswad R, Kanaan RA, Rico MC, Owen TA, Barbe MF, Safadi FF, Popoff SN. Connective tissue growth factor (CTGF) acts as a downstream mediator of TGF-beta1 to induce mesenchymal cell condensation. Journal of Cellular Physiology. 210: 398-410. PMID 17111364 DOI: 10.1002/Jcp.20850  0.665
2007 Abdelmagid SM, Barbe MF, Arango-Hisijara I, Owen TA, Popoff SN, Safadi FF. Osteoactivin acts as downstream mediator of BMP-2 effects on osteoblast function. Journal of Cellular Physiology. 210: 26-37. PMID 17034042 DOI: 10.1002/Jcp.20841  0.766
2007 Arango‐Hisijara I, McCarthy JJ, Safadi FF, Popoff SN. Effects of Connective Tissue Growth Factor (CTGF) and Osteoactivin (OA) on Bone Healing in a Segmental Defect Model in Rats The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A135-A  0.387
2006 Manns JM, Uknis AB, Rico MC, Agelan A, Castaneda J, Arango I, Barbe MF, Safadi FF, Popoff SN, DeLa Cadena RA. A peptide from thrombospondin 1 modulates experimental erosive arthritis by regulating connective tissue growth factor. Arthritis and Rheumatism. 54: 2415-22. PMID 16869004 DOI: 10.1002/Art.22021  0.327
2004 Litvin J, Selim AH, Montgomery MO, Lehmann K, Rico MC, Devlin H, Bednarik DP, Safadi FF. Expression and function of periostin-isoforms in bone. Journal of Cellular Biochemistry. 92: 1044-61. PMID 15258926 DOI: 10.1002/Jcb.20115  0.463
2004 Kelsen SG, Aksoy MO, Yang Y, Shahabuddin S, Litvin J, Safadi F, Rogers TJ. The chemokine receptor CXCR3 and its splice variant are expressed in human airway epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L584-91. PMID 15155273 DOI: 10.1152/Ajplung.00453.2003  0.351
2004 Safadi FF, Stapleton PP, Freeman TA, Casteneda JL, Arango I, Popoff SN, Daly JM. Delayed fracture healing in iNOS knockout mice Journal of the American College of Surgeons. 199: 49. DOI: 10.1016/J.Jamcollsurg.2004.05.096  0.32
2003 Schneider GB, Grecco KJ, Safadi FF, Popoff SN. The anabolic effects of vitamin D-binding protein-macrophage activating factor (DBP-MAF) and a novel small peptide on bone. Critical Reviews in Eukaryotic Gene Expression. 13: 277-84. PMID 14696974 DOI: 10.1615/Critreveukaryotgeneexpr.V13.I24.190  0.424
2003 Selim AA, Abdelmagid SM, Kanaan RA, Smock SL, Owen TA, Popoff SN, Safadi FF. Anti-osteoactivin antibody inhibits osteoblast differentiation and function in vitro. Critical Reviews in Eukaryotic Gene Expression. 13: 265-75. PMID 14696973 DOI: 10.1615/Critreveukaryotgeneexpr.V13.I24.180  0.77
2003 Owen TA, Smock SL, Prakash S, Pinder L, Brees D, Krull D, Castleberry TA, Clancy YC, Marks SC, Safadi FF, Popoff SN. Identification and Characterization of the Genes Encoding Human and Mouse Osteoactivin Critical Reviews in Eukaryotic Gene Expression. 13: 205-220. PMID 14696968 DOI: 10.1615/Critreveukaryotgeneexpr.V13.I24.130  0.436
2003 Barr AE, Safadi FF, Gorzelany I, Amin M, Popoff SN, Barbe MF. Repetitive, negligible force reaching in rats induces pathological overloading of upper extremity bones. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 2023-32. PMID 14606516 DOI: 10.1359/Jbmr.2003.18.11.2023  0.44
2003 Safadi FF, Xu J, Smock SL, Kanaan RA, Selim AH, Odgren PR, Marks SC, Owen TA, Popoff SN. Expression of connective tissue growth factor in bone: its role in osteoblast proliferation and differentiation in vitro and bone formation in vivo. Journal of Cellular Physiology. 196: 51-62. PMID 12767040 DOI: 10.1002/Jcp.10319  0.752
2003 Ivkovic S, Yoon BS, Popoff SN, Safadi FF, Libuda DE, Stephenson RC, Daluiski A, Lyons KM. Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Development (Cambridge, England). 130: 2779-91. PMID 12736220 DOI: 10.1242/Dev.00505  0.384
2003 Barbe MF, Barr AE, Gorzelany I, Amin M, Gaughan JP, Safadi FF. Chronic repetitive reaching and grasping results in decreased motor performance and widespread tissue responses in a rat model of MSD. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 21: 167-76. PMID 12507595 DOI: 10.1016/S0736-0266(02)00086-4  0.322
2002 Van Wesenbeeck L, Odgren PR, MacKay CA, D'Angelo M, Safadi FF, Popoff SN, Van Hul W, Marks SC. The osteopetrotic mutation toothless (tl) is a loss-of-function frameshift mutation in the rat Csf1 gene: Evidence of a crucial role for CSF-1 in osteoclastogenesis and endochondral ossification. Proceedings of the National Academy of Sciences of the United States of America. 99: 14303-8. PMID 12379742 DOI: 10.1073/Pnas.202332999  0.341
2001 Odgren PR, Kim N, Van Wesenbeeck L, Mackay C, Mason-Savas A, Safadi FF, Popoff SN, Lengner C, Van-Hul W, Choi Y, Marks SC. Evidence that the rat osteopetrotic mutation toothless (tl) is not in the TNFSF11 (TRANCE, RANKL, ODF, OPGL) gene International Journal of Developmental Biology. 45: 853-859. PMID 11804028 DOI: 10.1387/Ijdb.11804028  0.414
2001 Safadi FF, Xu J, Smock SL, Rico MC, Owen TA, Popoff SN. Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts Journal of Cellular Biochemistry. 84: 12-26. PMID 11746512 DOI: 10.1002/Jcb.1259  0.515
2000 Safadi FF, Dissanayake IR, Goodman GG, Jago RA, Baker AE, Bowman AR, Sass DA, Popoff SN, Epstein S. Influence of estrogen deficiency and replacement on T-cell populations in rat lymphoid tissues and organs. Endocrine. 12: 81-8. PMID 10855695 DOI: 10.1385/Endo:12:1:81  0.369
2000 Xu J, Smock SL, Safadi FF, Rosenzweig AB, Odgren PR, Marks SC, Owen TA, Popoff SN. Cloning the full-length cDNA for rat connective tissue growth factor: Implications for skeletal development Journal of Cellular Biochemistry. 77: 103-115. PMID 10679821 DOI: 10.1002/(Sici)1097-4644(20000401)77:1<103::Aid-Jcb11>3.0.Co;2-G  0.496
1999 Safadi FF, Hermey DC, Popoff SN, Seifert MF. Skeletal resistance to 1,25-dihydroxyvitamin D 3 in osteopetrotic rats Endocrine. 11: 309-319. PMID 10786828 DOI: 10.1385/Endo:11:3:309  0.353
1999 Odgren PR, Popoff SN, Safadi FF, MacKay CA, Mason-Savas A, Seifert MF, Marks SC. The toothless osteopetrotic rat has a normal vitamin D-binding protein-macrophage activating factor (DBP-MAF) cascade and chondrodysplasia resistant to treatments with colony stimulating factor-1 (CSF-1) and/or DBP-MAF Bone. 25: 175-181. PMID 10456382 DOI: 10.1016/S8756-3282(99)00149-0  0.425
Show low-probability matches.