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Robert J. Keenan - Publications

Affiliations: 
Biochemistry and Molecular Biology University of Chicago, Chicago, IL 
Area:
Biochemistry

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 SmalinskaitÄ— L, Kim MK, Lewis AJO, Keenan RJ, Hegde RS. Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature. PMID 36261528 DOI: 10.1038/s41586-022-05336-2  0.357
2022 Sundaram A, Yamsek M, Zhong F, Hooda Y, Hegde RS, Keenan RJ. Substrate-driven assembly of a translocon for multipass membrane proteins. Nature. PMID 36261522 DOI: 10.1038/s41586-022-05330-8  0.785
2021 Hegde RS, Keenan RJ. The mechanisms of integral membrane protein biogenesis. Nature Reviews. Molecular Cell Biology. PMID 34556847 DOI: 10.1038/s41580-021-00413-2  0.365
2020 McGilvray PT, Anghel SA, Sundaram A, Zhong F, Trnka MJ, Fuller JR, Hu H, Burlingame AL, Keenan RJ. An ER translocon for multi-pass membrane protein biogenesis. Elife. 9. PMID 32820719 DOI: 10.7554/Elife.56889  0.745
2020 O'Donnell JP, Phillips BP, Yagita Y, Juszkiewicz S, Wagner A, Malinverni D, Keenan RJ, Miller EA, Hegde RS. The architecture of EMC reveals a path for membrane protein insertion. Elife. 9. PMID 32459176 DOI: 10.7554/Elife.57887  0.452
2020 O'Donnell JP, Phillips BP, Yagita Y, Juszkiewicz S, Wagner A, Malinverni D, Keenan RJ, Miller EA, Hegde RS. Author response: The architecture of EMC reveals a path for membrane protein insertion Elife. DOI: 10.7554/Elife.57887.Sa2  0.413
2018 Mateja A, Keenan RJ. A structural perspective on tail-anchored protein biogenesis by the GET pathway. Current Opinion in Structural Biology. 51: 195-202. PMID 30173121 DOI: 10.1016/J.Sbi.2018.07.009  0.442
2017 Anghel SA, McGilvray PT, Hegde RS, Keenan RJ. Identification of Oxa1 Homologs Operating in the Eukaryotic Endoplasmic Reticulum. Cell Reports. 21: 3708-3716. PMID 29281821 DOI: 10.1016/J.Celrep.2017.12.006  0.797
2017 Zalisko BE, Chan C, Denic V, Rock RS, Keenan RJ. Tail-Anchored Protein Insertion by a Single Get1/2 Heterodimer. Cell Reports. 20: 2287-2293. PMID 28877464 DOI: 10.1016/J.Celrep.2017.08.035  0.764
2017 Wohlever ML, Mateja A, McGilvray PT, Day KJ, Keenan RJ. Msp1 Is a Membrane Protein Dislocase for Tail-Anchored Proteins. Molecular Cell. 67: 194-202.e6. PMID 28712723 DOI: 10.1016/J.Molcel.2017.06.019  0.809
2017 Srivastava R, Zalisko BE, Keenan RJ, Howell SH. The GET System Inserts the Tail-Anchored Protein, SYP72, into Endoplasmic Reticulum Membranes. Plant Physiology. 173: 1137-1145. PMID 27923985 DOI: 10.1104/Pp.16.00928  0.773
2016 Itakura E, Zavodszky E, Shao S, Wohlever ML, Keenan RJ, Hegde RS. Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation. Molecular Cell. PMID 27345149 DOI: 10.1016/J.Molcel.2016.05.020  0.42
2016 Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, ... ... Keenan RJ, et al. Data publication with the structural biology data grid supports live analysis. Nature Communications. 7: 10882. PMID 26947396 DOI: 10.1038/Ncomms10882  0.469
2015 Dominik PK, Borowska MT, Dalmas O, Kim SS, Perozo E, Keenan RJ, Kossiakoff AA. Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs. Structure (London, England : 1993). PMID 26749445 DOI: 10.1016/J.Str.2015.11.014  0.633
2015 Borowska MT, Dominik PK, Anghel SA, Kossiakoff AA, Keenan RJ. A YidC-like Protein in the Archaeal Plasma Membrane. Structure (London, England : 1993). 23: 1715-24. PMID 26256539 DOI: 10.1016/J.Str.2015.06.025  0.788
2015 Mateja A, Paduch M, Chang HY, Szydlowska A, Kossiakoff AA, Hegde RS, Keenan RJ. Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo. Science (New York, N.Y.). 347: 1152-5. PMID 25745174 DOI: 10.1126/Science.1261671  0.63
2015 Bestul AJ, Christensen JR, Grzegorzewska AP, Burke TA, Sees JA, Carroll RT, Sirotkin V, Keenan RJ, Kovar DR. Fission yeast profilin is tailored to facilitate actin assembly by the cytokinesis formin Cdc12. Molecular Biology of the Cell. 26: 283-93. PMID 25392301 DOI: 10.1091/Mbc.E13-05-0281  0.306
2011 Hegde RS, Keenan RJ. Tail-anchored membrane protein insertion into the endoplasmic reticulum. Nature Reviews. Molecular Cell Biology. 12: 787-98. PMID 22086371 DOI: 10.1038/Nrm3226  0.441
2011 Mariappan M, Mateja A, Dobosz M, Bove E, Hegde RS, Keenan RJ. The mechanism of membrane-associated steps in tail-anchored protein insertion. Nature. 477: 61-6. PMID 21866104 DOI: 10.1038/Nature10362  0.467
2011 Sherrill J, Mariappan M, Dominik P, Hegde RS, Keenan RJ. A conserved archaeal pathway for tail-anchored membrane protein insertion. Traffic (Copenhagen, Denmark). 12: 1119-23. PMID 21658170 DOI: 10.1111/J.1600-0854.2011.01229.X  0.451
2010 Mariappan M, Li X, Stefanovic S, Sharma A, Mateja A, Keenan RJ, Hegde RS. A ribosome-associating factor chaperones tail-anchored membrane proteins. Nature. 466: 1120-4. PMID 20676083 DOI: 10.1038/Nature09296  0.454
2010 Mateja A, Szlachcic A, Downing M, Dobosz M, Mariappan M, Hegde RS, Keenan RJ. Tail-Anchored Membrane Protein Recognition by Get3 Biophysical Journal. 98: 498a. DOI: 10.1016/J.Bpj.2009.12.2715  0.459
2009 Mateja A, Szlachcic A, Downing ME, Dobosz M, Mariappan M, Hegde RS, Keenan RJ. The structural basis of tail-anchored membrane protein recognition by Get3. Nature. 461: 361-6. PMID 19675567 DOI: 10.1038/Nature08319  0.465
2005 Yuan L, Kurek I, English J, Keenan R. Laboratory-directed protein evolution. Microbiology and Molecular Biology Reviews : Mmbr. 69: 373-92. PMID 16148303 DOI: 10.1128/Mmbr.69.3.373-392.2005  0.352
2005 Keenan RJ, Siehl DL, Gorton R, Castle LA. DNA shuffling as a tool for protein crystallization. Proceedings of the National Academy of Sciences of the United States of America. 102: 8887-92. PMID 15951425 DOI: 10.1073/Pnas.0502497102  0.333
2002 Burns KE, Keenan RJ, Grgurich WF, Manzetti JD, Zenati MA. Outcomes of lung volume reduction surgery followed by lung transplantation: a matched cohort study. The Annals of Thoracic Surgery. 73: 1587-93. PMID 12022555 DOI: 10.1016/S0003-4975(02)03499-9  0.3
2001 Keenan RJ, Freymann DM, Stroud RM, Walter P. The signal recognition particle. Annual Review of Biochemistry. 70: 755-75. PMID 11395422 DOI: 10.1146/Annurev.Biochem.70.1.755  0.774
2000 Walter P, Keenan R, Schmitz U. Perspectives: structural biology. SRP--where the RNA and membrane worlds meet. Science (New York, N.Y.). 287: 1212-3. PMID 10712156 DOI: 10.1126/Science.287.5456.1212  0.485
1999 Schmitz U, Behrens S, Freymann DM, Keenan RJ, Lukavsky P, Walter P, James TL. Structure of the phylogenetically most conserved domain of SRP RNA. Rna (New York, N.Y.). 5: 1419-29. PMID 10580470 DOI: 10.1017/S1355838299991458  0.729
1999 Freymann DM, Keenan RJ, Stroud RM, Walter P. Functional changes in the structure of the SRP GTPase on binding GDP and Mg2+GDP. Nature Structural Biology. 6: 793-801. PMID 10426959 DOI: 10.1038/11572  0.747
1998 Keenan RJ, Freymann DM, Walter P, Stroud RM. Crystal structure of the signal sequence binding subunit of the signal recognition particle. Cell. 94: 181-91. PMID 9695947 DOI: 10.1016/S0092-8674(00)81418-X  0.737
1998 Gammie JS, Keenan RJ, Pham SM, McGrath MF, Hattler BG, Khoshbin E, Griffith BP. Single- versus double-lung transplantation for pulmonary hypertension. The Journal of Thoracic and Cardiovascular Surgery. 115: 397-402; discussion . PMID 9475535 DOI: 10.1016/S0022-5223(98)70284-3  0.301
1998 McCurry KR, Keenan RJ. Controlling perioperative morbidity and mortality after lung transplantation for pulmonary hypertension Transplantation Reviews. 12: 209-213. DOI: 10.1016/S0955-470X(98)80012-8  0.307
1997 Freymann DM, Keenan RJ, Stroud RM, Walter P. Structure of the conserved GTPase domain of the signal recognition particle. Nature. 385: 361-4. PMID 9002524 DOI: 10.1038/385361A0  0.761
1997 Rutenber E, Fauman EB, Keenan RJ, Fong S, Furth PS, Montellano PROd, Meng E, Kuntz ID, DeCamp DL, Salto R, Rose JR, Craik CS, Stroud RM. Structure of a non-peptide inhibitor complexed with HIV-1 protease. Developing a cycle of structure-based drug design. Journal of Biological Chemistry. 268: 15343-15346. DOI: 10.2210/Pdb2Aid/Pdb  0.433
1996 Schmitz U, Freymann DM, James TL, Keenan RJ, Vinayak R, Walter P. NMR studies of the most conserved RNA domain of the mammalian signal recognition particle (SRP). Rna (New York, N.Y.). 2: 1213-27. PMID 8972771  0.689
1996 Zenati M, Pham SM, Keenan RJ, Griffith BP. Extracorporeal membrane oxygenation for lung transplant recipients with primary severe donor lung dysfunction Transplant International. 9: 227-230. PMID 8723191 DOI: 10.1007/Bf00335390  0.307
1996 Freymann D, Keenan R, Stroud R, Walter P. Progress torwards the crystal structure of Ffh, the bacterial homolog of SRP54 Acta Crystallographica Section a Foundations of Crystallography. 52: C167-C167. DOI: 10.1107/S0108767396092574  0.722
1995 Glassman LR, Keenan RJ, Fabrizio MC, Sonett JR, Bierman MI, Pham SM, Griffith BP. Extracorporeal membrane oxygenation as an adjunct treatment for primary graft failure in adult lung transplant recipients The Journal of Thoracic and Cardiovascular Surgery. 110: 723-727. PMID 7564439 DOI: 10.1016/S0022-5223(95)70104-4  0.354
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