Dani Brunner - Publications

Affiliations: 
PsychoGenics Inc, Tarrytown, NY, United States 

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Alexandrov V, Brunner D, Menalled LB, Kudwa A, Watson-Johnson J, Mazzella M, Russell I, Ruiz MC, Torello J, Sabath E, Sanchez A, Gomez M, Filipov I, Cox K, Kwan M, et al. Large-scale phenome analysis defines a behavioral signature for Huntington's disease genotype in mice. Nature Biotechnology. PMID 27376585 DOI: 10.1038/nbt.3587  0.32
2016 Onajole OK, Vallerini GP, Eaton JB, Lukas RJ, Brunner D, Caldarone BJ, Kozikowski AP. Synthesis and Behavioral Studies of Chiral Cyclopropanes as Selective α4β2-Nicotinic Acetylcholine Receptor Partial Agonists Exhibiting an Antidepressant Profile. Part III. Acs Chemical Neuroscience. PMID 27035276 DOI: 10.1021/acschemneuro.6b00050  1
2015 Brunner D, Kabitzke P, He D, Cox K, Thiede L, Hanania T, Sabath E, Alexandrov V, Saxe M, Peles E, Mills A, Spooren W, Ghosh A, Feliciano P, Benedetti M, et al. Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder. Plos One. 10: e0134572. PMID 26273832 DOI: 10.1371/journal.pone.0134572  0.6
2015 Alexandrov V, Brunner D, Hanania T, Leahy E. Reprint of: Highthroughtput analysis of behavior for drug discovery. European Journal of Pharmacology. 753: 127-34. PMID 25744878 DOI: 10.1016/j.ejphar.2015.02.037  1
2015 Alexandrov V, Brunner D, Hanania T, Leahy E. High-throughput analysis of behavior for drug discovery. European Journal of Pharmacology. 750: 82-9. PMID 25592319 DOI: 10.1016/j.ejphar.2014.11.047  1
2014 Onajole OK, Eaton JB, Lukas RJ, Brunner D, Thiede L, Caldarone BJ, Kozikowski AP. Enantiopure Cyclopropane-Bearing Pyridyldiazabicyclo[3.3.0]octanes as Selective α4β2-nAChR Ligands. Acs Medicinal Chemistry Letters. 5: 1196-201. PMID 25408831 DOI: 10.1021/ml500129k  1
2014 Menalled L, Brunner D. Animal models of Huntington's disease for translation to the clinic: best practices. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1375-90. PMID 25216369 DOI: 10.1002/mds.26006  0.6
2014 Stout JC, Queller S, Baker KN, Cowlishaw S, Sampaio C, Fitzer-Attas C, Borowsky B. HD-CAB: a cognitive assessment battery for clinical trials in Huntington's disease 1,2,3. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1281-8. PMID 25209258 DOI: 10.1002/mds.25964  0.6
2014 Munafò M, Noble S, Browne WJ, Brunner D, Button K, Ferreira J, Holmans P, Langbehn D, Lewis G, Lindquist M, Tilling K, Wagenmakers EJ, Blumenstein R. Scientific rigor and the art of motorcycle maintenance. Nature Biotechnology. 32: 871-3. PMID 25203032 DOI: 10.1038/nbt.3004  1
2014 Milekic MH, Xin Y, O'Donnell A, Kumar KK, Bradley-Moore M, Malaspina D, Moore H, Brunner D, Ge Y, Edwards J, Paul S, Haghighi FG, Gingrich JA. Age-related sperm DNA methylation changes are transmitted to offspring and associated with abnormal behavior and dysregulated gene expression. Molecular Psychiatry. PMID 25092244 DOI: 10.1038/mp.2014.84  0.6
2014 Farrar AM, Murphy CA, Paterson NE, Oakeshott S, He D, Alosio W, McConnell K, Menalled LB, Ramboz S, Park LC, Howland D, Brunner D. Cognitive deficits in transgenic and knock-in HTT mice parallel those in Huntington's disease. Journal of Huntington's Disease. 3: 145-58. PMID 25062858 DOI: 10.3233/JHD-130061  1
2014 Menalled LB, Kudwa AE, Oakeshott S, Farrar A, Paterson N, Filippov I, Miller S, Kwan M, Olsen M, Beltran J, Torello J, Fitzpatrick J, Mushlin R, Cox K, McConnell K, ... ... Brunner D, et al. Genetic deletion of transglutaminase 2 does not rescue the phenotypic deficits observed in R6/2 and zQ175 mouse models of Huntington's disease. Plos One. 9: e99520. PMID 24955833 DOI: 10.1371/journal.pone.0099520  1
2013 Oakeshott S, Farrar A, Port R, Cummins-Sutphen J, Berger J, Watson-Johnson J, Ramboz S, Howland D, Brunner D. Deficits in a Simple Visual Go/No-go Discrimination Task in Two Mouse Models of Huntington's Disease. Plos Currents. 5. PMID 24270512 DOI: 10.1371/currents.hd.fe74c94bdd446a0470f6f905a30b5dd1  1
2013 Kudwa AE, Menalled LB, Oakeshott S, Murphy C, Mushlin R, Fitzpatrick J, Miller SF, McConnell K, Port R, Torello J, Howland D, Ramboz S, Brunner D. Increased Body Weight of the BAC HD Transgenic Mouse Model of Huntington's Disease Accounts for Some but Not All of the Observed HD-like Motor Deficits. Plos Currents. 5. PMID 24042107 DOI: 10.1371/currents.hd.0ab4f3645aff523c56ecc8ccbe41a198  1
2013 Markou A, Salamone JD, Bussey TJ, Mar AC, Brunner D, Gilmour G, Balsam P. Measuring reinforcement learning and motivation constructs in experimental animals: relevance to the negative symptoms of schizophrenia. Neuroscience and Biobehavioral Reviews. 37: 2149-65. PMID 23994273 DOI: 10.1016/j.neubiorev.2013.08.007  0.6
2013 Hanson JE, La H, Plise E, Chen YH, Ding X, Hanania T, Sabath EV, Alexandrov V, Brunner D, Leahy E, Steiner P, Liu L, Scearce-Levie K, Zhou Q. SAHA enhances synaptic function and plasticity in vitro but has limited brain availability in vivo and does not impact cognition. Plos One. 8: e69964. PMID 23922875 DOI: 10.1371/journal.pone.0069964  1
2013 Balci F, Oakeshott S, Shamy JL, El-Khodor BF, Filippov I, Mushlin R, Port R, Connor D, Paintdakhi A, Menalled L, Ramboz S, Howland D, Kwak S, Brunner D. High-Throughput Automated Phenotyping of Two Genetic Mouse Models of Huntington's Disease. Plos Currents. 5. PMID 23863947 DOI: 10.1371/currents.hd.124aa0d16753f88215776fba102ceb29  1
2013 Zhang HK, Yu LF, Eaton JB, Whiteaker P, Onajole OK, Hanania T, Brunner D, Lukas RJ, Kozikowski AP. Chemistry, pharmacology, and behavioral studies identify chiral cyclopropanes as selective α4β2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile. Part II. Journal of Medicinal Chemistry. 56: 5495-504. PMID 23734673 DOI: 10.1021/jm400510u  0.6
2013 Gunosewoyo H, Midzak A, Gaisina IN, Sabath EV, Fedolak A, Hanania T, Brunner D, Papadopoulos V, Kozikowski AP. Characterization of maleimide-based glycogen synthase kinase-3 (GSK-3) inhibitors as stimulators of steroidogenesis. Journal of Medicinal Chemistry. 56: 5115-29. PMID 23725591 DOI: 10.1021/jm400511s  1
2012 Oakeshott S, Port R, Cummins-Sutphen J, Berger J, Watson-Johnson J, Ramboz S, Paterson N, Kwak S, Howland D, Brunner D. A mixed fixed ratio/progressive ratio procedure reveals an apathy phenotype in the BAC HD and the z_Q175 KI mouse models of Huntington's disease. Plos Currents. 4: e4f972cffe82c0. PMID 23925262 DOI: 10.1371/4f972cffe82c0  1
2012 Menalled LB, Kudwa AE, Miller S, Fitzpatrick J, Watson-Johnson J, Keating N, Ruiz M, Mushlin R, Alosio W, McConnell K, Connor D, Murphy C, Oakeshott S, Kwan M, Beltran J, ... ... Brunner D, et al. Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175. Plos One. 7: e49838. PMID 23284626 DOI: 10.1371/journal.pone.0049838  1
2012 Yu LF, Eaton JB, Fedolak A, Zhang HK, Hanania T, Brunner D, Lukas RJ, Kozikowski AP. Discovery of highly potent and selective α4β2-nicotinic acetylcholine receptor (nAChR) partial agonists containing an isoxazolylpyridine ether scaffold that demonstrate antidepressant-like activity. Part II. Journal of Medicinal Chemistry. 55: 9998-10009. PMID 23092294 DOI: 10.1021/jm301177j  1
2012 Zhang HK, Eaton JB, Yu LF, Nys M, Mazzolari A, van Elk R, Smit AB, Alexandrov V, Hanania T, Sabath E, Fedolak A, Brunner D, Lukas RJ, Vistoli G, Ulens C, et al. Insights into the structural determinants required for high-affinity binding of chiral cyclopropane-containing ligands to α4β2-nicotinic acetylcholine receptors: an integrated approach to behaviorally active nicotinic ligands. Journal of Medicinal Chemistry. 55: 8028-37. PMID 22928944 DOI: 10.1021/jm3008739  0.6
2012 Menalled L, El-Khodor BF, Hornberger M, Park L, Howland D, Brunner D. Effect of the rd1 mutation on motor performance in R6/2 and wild type mice. Plos Currents. 4: RRN1303. PMID 22367489 DOI: 10.1371/currents.RRN1303  1
2012 Zhang H, Tückmantel W, Eaton JB, Yuen PW, Yu LF, Bajjuri KM, Fedolak A, Wang D, Ghavami A, Caldarone B, Paterson NE, Lowe DA, Brunner D, Lukas RJ, Kozikowski AP. Chemistry and behavioral studies identify chiral cyclopropanes as selective α4β2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile. Journal of Medicinal Chemistry. 55: 717-24. PMID 22171543 DOI: 10.1021/jm201157c  0.6
2012 Brunner D, Balcı F, Ludvig EA. Comparative psychology and the grand challenge of drug discovery in psychiatry and neurodegeneration. Behavioural Processes. 89: 187-95. PMID 22155361 DOI: 10.1016/j.beproc.2011.10.011  1
2012 Yu LF, Tückmantel W, Eaton JB, Caldarone B, Fedolak A, Hanania T, Brunner D, Lukas RJ, Kozikowski AP. Identification of novel α4β2-nicotinic acetylcholine receptor (nAChR) agonists based on an isoxazole ether scaffold that demonstrate antidepressant-like activity. Journal of Medicinal Chemistry. 55: 812-23. PMID 22148173 DOI: 10.1021/jm201301h  1
2012 Brunner D, Alexandrov V, Caldarone B, Hanania T, Lowe D, Schneider J, Chandrasekhar J. Behavior-Based Screening as an Approach to Polypharmacological Ligands Polypharmacology in Drug Discovery. 303-313. DOI: 10.1002/9781118098141.ch14  1
2011 Oakeshott S, Port RG, Cummins-Sutphen J, Watson-Johnson J, Ramboz S, Park L, Howland D, Brunner D. HD mouse models reveal clear deficits in learning to perform a simple instrumental response. Plos Currents. 3: RRN1282. PMID 22512000 DOI: 10.1371/currents.RRN1282  0.32
2011 Roberds SL, Filippov I, Alexandrov V, Hanania T, Brunner D. Rapid, computer vision-enabled murine screening system identifies neuropharmacological potential of two new mechanisms. Frontiers in Neuroscience. 5: 103. PMID 21927596 DOI: 10.3389/fnins.2011.00103  1
2011 Liu J, Yu LF, Eaton JB, Caldarone B, Cavino K, Ruiz C, Terry M, Fedolak A, Wang D, Ghavami A, Lowe DA, Brunner D, Lukas RJ, Kozikowski AP. Discovery of isoxazole analogues of sazetidine-A as selective α4β2-nicotinic acetylcholine receptor partial agonists for the treatment of depression. Journal of Medicinal Chemistry. 54: 7280-8. PMID 21905669 DOI: 10.1021/jm200855b  1
2011 Oakeshott S, Balci F, Filippov I, Murphy C, Port R, Connor D, Paintdakhi A, Lesauter J, Menalled L, Ramboz S, Kwak S, Howland D, Silver R, Brunner D. Circadian Abnormalities in Motor Activity in a BAC Transgenic Mouse Model of Huntington's Disease. Plos Currents. 3: RRN1225. PMID 21479110 DOI: 10.1371/currents.RRN1225  1
2010 Caldarone BJ, Paterson NE, Zhou J, Brunner D, Kozikowski AP, Westphal KG, Korte-Bouws GA, Prins J, Korte SM, Olivier B, Ghavami A. The novel triple reuptake inhibitor JZAD-IV-22 exhibits an antidepressant pharmacological profile without locomotor stimulant or sensitization properties. The Journal of Pharmacology and Experimental Therapeutics. 335: 762-70. PMID 20864506 DOI: 10.1124/jpet.110.174011  0.6
2010 Balci F, Ludvig EA, Brunner D. Within-session modulation of timed anticipatory responding: when to start responding. Behavioural Processes. 85: 204-6. PMID 20600698 DOI: 10.1016/j.beproc.2010.06.012  1
2010 Menalled LB, Patry M, Ragland N, Lowden PA, Goodman J, Minnich J, Zahasky B, Park L, Leeds J, Howland D, Signer E, Tobin AJ, Brunner D. Comprehensive behavioral testing in the R6/2 mouse model of Huntington's disease shows no benefit from CoQ10 or minocycline. Plos One. 5: e9793. PMID 20339553 DOI: 10.1371/journal.pone.0009793  0.6
2010 Balci F, Ludvig EA, Abner R, Zhuang X, Poon P, Brunner D. Motivational effects on interval timing in dopamine transporter (DAT) knockdown mice. Brain Research. 1325: 89-99. PMID 20167208 DOI: 10.1016/j.brainres.2010.02.034  1
2009 Balci F, Day M, Rooney A, Brunner D. Disrupted temporal control in the R6/2 mouse model of Huntington's disease. Behavioral Neuroscience. 123: 1353-8. PMID 20001119 DOI: 10.1037/a0017650  1
2009 Nemirovsky SI, Avale ME, Brunner D, Rubinstein M. Reward-seeking and discrimination deficits displayed by hypodopaminergic mice are prevented in mice lacking dopamine D4 receptors. Synapse (New York, N.Y.). 63: 991-7. PMID 19598175 DOI: 10.1002/syn.20680  0.6
2009 Menalled L, El-Khodor BF, Patry M, Suárez-Fariñas M, Orenstein SJ, Zahasky B, Leahy C, Wheeler V, Yang XW, MacDonald M, Morton AJ, Bates G, Leeds J, Park L, Howland D, ... ... Brunner D, et al. Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models. Neurobiology of Disease. 35: 319-36. PMID 19464370 DOI: 10.1016/j.nbd.2009.05.007  0.6
2009 Balci F, Gallistel CR, Allen BD, Frank KM, Gibson JM, Brunner D. Acquisition of peak responding: what is learned? Behavioural Processes. 80: 67-75. PMID 18950695 DOI: 10.1016/j.beproc.2008.09.010  0.6
2008 Balci F, Ludvig EA, Gibson JM, Allen BD, Frank KM, Kapustinski BJ, Fedolak TE, Brunner D. Pharmacological manipulations of interval timing using the peak procedure in male C3H mice. Psychopharmacology. 201: 67-80. PMID 18648777 DOI: 10.1007/s00213-008-1248-y  0.6
2008 El-Khodor BF, Edgar N, Chen A, Winberg ML, Joyce C, Brunner D, Suárez-Fariñas M, Heyes MP. Identification of a battery of tests for drug candidate evaluation in the SMNDelta7 neonate model of spinal muscular atrophy. Experimental Neurology. 212: 29-43. PMID 18455159 DOI: 10.1016/j.expneurol.2008.02.025  0.6
2008 Houghten RA, Pinilla C, Giulianotti MA, Appel JR, Dooley CT, Nefzi A, Ostresh JM, Yu Y, Maggiora GM, Medina-Franco JL, Brunner D, Schneider J. Strategies for the use of mixture-based synthetic combinatorial libraries: scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods. Journal of Combinatorial Chemistry. 10: 3-19. PMID 18067268 DOI: 10.1021/cc7001205  0.6
2008 Balci F, Papachristos EB, Gallistel CR, Brunner D, Gibson J, Shumyatsky GP. Interval timing in genetically modified mice: a simple paradigm. Genes, Brain, and Behavior. 7: 373-84. PMID 17696995 DOI: 10.1111/j.1601-183X.2007.00348.x  0.6
2007 Roy K, Murtie JC, El-Khodor BF, Edgar N, Sardi SP, Hooks BM, Benoit-Marand M, Chen C, Moore H, O'Donnell P, Brunner D, Corfas G. Loss of erbB signaling in oligodendrocytes alters myelin and dopaminergic function, a potential mechanism for neuropsychiatric disorders. Proceedings of the National Academy of Sciences of the United States of America. 104: 8131-6. PMID 17483467 DOI: 10.1073/pnas.0702157104  0.6
2006 Cagniard B, Balsam PD, Brunner D, Zhuang X. Mice with chronically elevated dopamine exhibit enhanced motivation, but not learning, for a food reward. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1362-70. PMID 16319913 DOI: 10.1038/sj.npp.1300966  0.6
2004 El-Khodor BF, Dimmler MH, Amara DA, Hofer M, Hen R, Brunner D. Juvenile 5HT(1B) receptor knockout mice exhibit reduced pharmacological sensitivity to 5HT(1A) receptor activation. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 22: 405-13. PMID 15380839 DOI: 10.1016/j.ijdevneu.2004.06.001  1
2004 Compan V, Zhou M, Grailhe R, Gazzara RA, Martin R, Gingrich J, Dumuis A, Brunner D, Bockaert J, Hen R. Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 412-9. PMID 14724239 DOI: 10.1523/JNEUROSCI.2806-03.2004  0.6
2003 Weller A, Leguisamo AC, Towns L, Ramboz S, Bagiella E, Hofer M, Hen R, Brunner D. Maternal effects in infant and adult phenotypes of 5HT1A and 5HT1B receptor knockout mice. Developmental Psychobiology. 42: 194-205. PMID 12555283 DOI: 10.1002/dev.10079  1
2002 Brunner D, Nestler E, Leahy E. In need of high-throughput behavioral systems. Drug Discovery Today. 7: S107-12. PMID 12546875 DOI: 10.1016/S1359-6446(02)02423-6  1
2002 Stefansson H, Sigurdsson E, Steinthorsdottir V, Bjornsdottir S, Sigmundsson T, Ghosh S, Brynjolfsson J, Gunnarsdottir S, Ivarsson O, Chou TT, Hjaltason O, Birgisdottir B, Jonsson H, Gudnadottir VG, Gudmundsdottir E, ... ... Brunner D, et al. Neuregulin 1 and susceptibility to schizophrenia. American Journal of Human Genetics. 71: 877-92. PMID 12145742 DOI: 10.1086/342734  0.6
2002 Kacelnik A, Brunner D. Timing and foraging: Gibbon's scalar expectancy theory and optimal patch exploitation Learning and Motivation. 33: 177-195. DOI: 10.1006/lmot.2001.1110  1
2001 Olivier B, Leahy C, Mullen T, Paylor R, Groppi VE, Sarnyai Z, Brunner D. The DBA/2J strain and prepulse inhibition of startle: a model system to test antipsychotics? Psychopharmacology. 156: 284-90. PMID 11549230 DOI: 10.1007/s002130100828  1
2000 Gross C, Santarelli L, Brunner D, Zhuang X, Hen R. Altered fear circuits in 5-HT(1A) receptor KO mice. Biological Psychiatry. 48: 1157-63. PMID 11137057 DOI: 10.1016/S0006-3223(00)01041-6  1
1999 Brunner D. Preference for sequences of rewards: further tests of a parallel discounting model. Behavioural Processes. 45: 87-99. PMID 24897529 DOI: 10.1016/S0376-6357(99)00011-X  1
1999 Brunner D, Buhot MC, Hen R, Hofer M. Anxiety, motor activation, and maternal-infant interactions in 5HT1B knockout mice. Behavioral Neuroscience. 113: 587-601. PMID 10443785 DOI: 10.1037/0735-7044.113.3.587  1
1999 Grailhe R, Waeber C, Dulawa SC, Hornung JP, Zhuang X, Brunner D, Geyer MA, Hen R. Increased exploratory activity and altered response to LSD in mice lacking the 5-HT(5A) receptor. Neuron. 22: 581-91. PMID 10197537  1
1998 Ramboz S, Oosting R, Amara DA, Kung HF, Blier P, Mendelsohn M, Mann JJ, Brunner D, Hen R. Serotonin receptor 1A knockout: an animal model of anxiety-related disorder. Proceedings of the National Academy of Sciences of the United States of America. 95: 14476-81. PMID 9826725 DOI: 10.1073/pnas.95.24.14476  1
1997 Brunner D, Hen R. Insights into the neurobiology of impulsive behavior from serotonin receptor knockout mice. Annals of the New York Academy of Sciences. 836: 81-105. PMID 9616795 DOI: 10.1111/j.1749-6632.1997.tb52356.x  1
1997 Brunner D, Fairhurst S, Stolovitzky G, Gibbon J. Mnemonics for variability: remembering food delay. Journal of Experimental Psychology. Animal Behavior Processes. 23: 68-83. PMID 9008863  1
1996 Brunner D, Kacelnik A, Gibbon J. Memory for inter-reinforcement interval variability and patch departure decisions in the starling, Sturnus vulgaris Animal Behaviour. 51: 1025-1045. DOI: 10.1006/anbe.1996.0105  1
1995 Brunner D, Gibbon J. Value of food aggregates: parallel versus serial discounting Animal Behaviour. 50: 1627-1634. DOI: 10.1016/0003-3472(95)80016-6  1
1994 Brunner D, Gibbon J, Fairhurst S. Choice between fixed and variable delays with different reward amounts. Journal of Experimental Psychology. Animal Behavior Processes. 20: 331-46. PMID 7964518  1
1992 Brunner D, Kacelnik A, Gibbon J. Optimal foraging and timing processes in the starling, Sturnus vulgaris: effect of inter-capture interval Animal Behaviour. 44: 597-613. DOI: 10.1016/S0003-3472(05)80289-1  1
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