Stefan G. Lechner, Ph.D. - Publications

Pharmacology University of Heidelberg, Heidelberg, Baden-Württemberg, Germany 
Sensory biology, pain

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Taberner FJ, Prato V, Schaefer I, Schrenk-Siemens K, Heppenstall PA, Lechner SG. Structure-guided examination of the mechanogating mechanism of PIEZO2. Proceedings of the National Academy of Sciences of the United States of America. PMID 31235572 DOI: 10.1073/pnas.1905985116  0.52
2018 Schaefer I, Prato V, Arcourt A, Taberner FJ, Lechner SG. [EXPRESS] Differential modulation of voltage-gated sodium channels by nerve growth factor in three major subsets of TrkA-expressing nociceptors. Molecular Pain. 1744806918814640. PMID 30387376 DOI: 10.1177/1744806918814640  0.52
2018 Dhandapani R, Arokiaraj CM, Taberner FJ, Pacifico P, Raja S, Nocchi L, Portulano C, Franciosa F, Maffei M, Hussain AF, de Castro Reis F, Reymond L, Perlas E, Garcovich S, Barth S, ... ... Lechner SG, et al. Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons. Nature Communications. 9: 1640. PMID 29691410 DOI: 10.1038/s41467-018-04049-3  0.52
2018 Narayanan P, Hütte M, Kudryasheva G, Taberner FJ, Lechner SG, Rehfeldt F, Gomez-Varela D, Schmidt M. Myotubularin related protein-2 and its phospholipid substrate PIPcontrol Piezo2-mediated mechanotransduction in peripheral sensory neurons. Elife. 7. PMID 29521261 DOI: 10.7554/eLife.32346  0.52
2017 Prato V, Taberner FJ, Hockley JRF, Callejo G, Arcourt A, Tazir B, Hammer L, Schad P, Heppenstall PA, Smith ES, Lechner SG. Functional and Molecular Characterization of Mechanoinsensitive "Silent" Nociceptors. Cell Reports. 21: 3102-3115. PMID 29241539 DOI: 10.1016/j.celrep.2017.11.066  0.52
2016 Arcourt A, Gorham L, Dhandapani R, Prato V, Taberner FJ, Wende H, Gangadharan V, Birchmeier C, Heppenstall PA, Lechner SG. Touch Receptor-Derived Sensory Information Alleviates Acute Pain Signaling and Fine-Tunes Nociceptive Reflex Coordination. Neuron. PMID 27989460 DOI: 10.1016/j.neuron.2016.11.027  0.52
2015 Arcourt A, Lechner SG. Peripheral and spinal circuits involved in mechanical allodynia. Pain. 156: 220-1. PMID 25599442 DOI: 10.1097/01.j.pain.0000460818.62406.38  0.44
2015 Schrenk-Siemens K, Wende H, Prato V, Song K, Rostock C, Loewer A, Utikal J, Lewin GR, Lechner SG, Siemens J. PIEZO2 is required for mechanotransduction in human stem cell-derived touch receptors. Nature Neuroscience. 18: 10-6. PMID 25469543 DOI: 10.1038/nn.3894  1
2014 Lewin GR, Lechner SG, Smith ES. Nerve growth factor and nociception: from experimental embryology to new analgesic therapy. Handbook of Experimental Pharmacology. 220: 251-82. PMID 24668476 DOI: 10.1007/978-3-642-45106-5_10  1
2014 Mitterberger MC, Lechner S, Mattesich M, Zwerschke W. Adipogenic differentiation is impaired in replicative senescent human subcutaneous adipose-derived stromal/progenitor cells Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 69: 13-24. PMID 23657974 DOI: 10.1093/gerona/glt043  1
2013 Lechner SG, Lewin GR. Hairy sensation. Physiology (Bethesda, Md.). 28: 142-50. PMID 23636260 DOI: 10.1152/physiol.00059.2012  1
2013 Lechner S, Mitterberger MC, Mattesich M, Zwerschke W. Role of C/EBPΒ-LAP and C/EBPΒ-LIP in early adipogenic differentiation of human white adipose-derived progenitors and at later stages in immature adipocytes Differentiation. 85: 20-31. PMID 23314288 DOI: 10.1016/j.diff.2012.11.001  1
2012 Wende H, Lechner SG, Birchmeier C. The transcription factor c-Maf in sensory neuron development. Transcription. 3: 285-9. PMID 22889842 DOI: 10.4161/trns.21809  1
2012 Mitterberger MC, Lechner S, Mattesich M, Kaiser A, Probst D, Wenger N, Pierer G, Zwerschke W. DLK1(PREF1) is a negative regulator of adipogenesis in CD105⁺/CD90⁺/CD34⁺/CD31⁻/FABP4⁻ adipose-derived stromal cells from subcutaneous abdominal fat pats of adult women. Stem Cell Research. 9: 35-48. PMID 22640926 DOI: 10.1016/j.scr.2012.04.001  1
2012 Frenzel H, Bohlender J, Pinsker K, Wohlleben B, Tank J, Lechner SG, Schiska D, Jaijo T, Rüschendorf F, Saar K, Jordan J, Millán JM, Gross M, Lewin GR. A genetic basis for mechanosensory traits in humans. Plos Biology. 10: e1001318. PMID 22563300 DOI: 10.1371/journal.pbio.1001318  1
2012 Wende H, Lechner SG, Cheret C, Bourane S, Kolanczyk ME, Pattyn A, Reuter K, Munier FL, Carroll P, Lewin GR, Birchmeier C. The transcription factor c-Maf controls touch receptor development and function. Science (New York, N.Y.). 335: 1373-6. PMID 22345400 DOI: 10.1126/science.1214314  1
2012 Heidenreich M, Lechner SG, Vardanyan V, Wetzel C, Cremers CW, De Leenheer EM, Aránguez G, Moreno-Pelayo MÁ, Jentsch TJ, Lewin GR. KCNQ4 K(+) channels tune mechanoreceptors for normal touch sensation in mouse and man. Nature Neuroscience. 15: 138-45. PMID 22101641 DOI: 10.1038/nn.2985  1
2012 Morandell D, Kaiser A, Herold S, Rostek U, Lechner S, Mitterberger MC, Jansen-Dürr P, Eilers M, Zwerschke W. The human papillomavirus type 16 E7 oncoprotein targets Myc-interacting zinc-finger protein-1. Virology. 422: 242-53. PMID 22099967 DOI: 10.1016/j.virol.2011.10.027  1
2012 Tappe-Theodor A, Constantin CE, Tegeder I, Lechner SG, Langeslag M, Lepcynzsky P, Wirotanseng RI, Kurejova M, Agarwal N, Nagy G, Todd A, Wettschureck N, Offermanns S, Kress M, Lewin GR, et al. Gα(q/11) signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization. Pain. 153: 184-96. PMID 22071319 DOI: 10.1016/j.pain.2011.10.014  1
2011 Smith ES, OmerbaÅ¡ić D, Lechner SG, Anirudhan G, Lapatsina L, Lewin GR. The molecular basis of acid insensitivity in the African naked mole-rat. Science (New York, N.Y.). 334: 1557-60. PMID 22174253 DOI: 10.1126/science.1213760  1
2011 Lechner SG, Siemens J. Sensory transduction, the gateway to perception: mechanisms and pathology. Embo Reports. 12: 292-5. PMID 21415857 DOI: 10.1038/embor.2011.45  1
2011 Lechner SG, Markworth S, Poole K, Smith ES, Lapatsina L, Frahm S, May M, Pischke S, Suzuki M, Ibañez-Tallon I, Luft FC, Jordan J, Lewin GR. The molecular and cellular identity of peripheral osmoreceptors. Neuron. 69: 332-44. PMID 21262470 DOI: 10.1016/j.neuron.2010.12.028  1
2011 Dreier K, Scheiden R, Lener B, Ehehalt D, Pircher H, Müller-Holzner E, Rostek U, Kaiser A, Fiedler M, Ressler S, Lechner S, Widschwendter A, Even J, Capesius C, Jansen-Dürr P, et al. Subcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situ. Virology. 409: 54-68. PMID 20970819 DOI: 10.1016/j.virol.2010.09.024  1
2010 Mitterberger MC, Mattesich M, Klaver E, Lechner S, Engelhardt T, Larcher L, Pierer G, Piza-Katzer H, Zwerschke W. Adipokine profile and insulin sensitivity in formerly obese women subjected to bariatric surgery or diet-induced long-term caloric restriction Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 65: 915-923. PMID 20576650 DOI: 10.1093/gerona/glq107  1
2009 Spoden GA, Rostek U, Lechner S, Mitterberger M, Mazurek S, Zwerschke W. Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply Experimental Cell Research. 315: 2765-2774. PMID 19563799 DOI: 10.1016/j.yexcr.2009.06.024  1
2009 Lechner SG, Lewin GR. Peripheral sensitisation of nociceptors via G-protein-dependent potentiation of mechanotransduction currents. The Journal of Physiology. 587: 3493-503. PMID 19505980 DOI: 10.1113/jphysiol.2009.175059  1
2009 Lechner SG, Frenzel H, Wang R, Lewin GR. Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development. The Embo Journal. 28: 1479-91. PMID 19322198 DOI: 10.1038/emboj.2009.73  1
2005 Lechner SG, Hussl S, Schicker KW, Drobny H, Boehm S. Presynaptic inhibition via a phospholipase C- and phosphatidylinositol bisphosphate-dependent regulation of neuronal Ca2+ channels. Molecular Pharmacology. 68: 1387-96. PMID 16099842 DOI: 10.1124/mol.105.014886  1
2005 Edelbauer H, Lechner SG, Mayer M, Scholze T, Boehm S. Presynaptic inhibition of transmitter release from rat sympathetic neurons by bradykinin. Journal of Neurochemistry. 93: 1110-21. PMID 15934932 DOI: 10.1111/j.1471-4159.2005.03084.x  1
2004 Lechner SG, Boehm S. Regulation of neuronal ion channels via P2Y receptors. Purinergic Signalling. 1: 31-41. PMID 18404398 DOI: 10.1007/s11302-004-4746-3  1
2004 Lechner SG, Dorostkar MM, Mayer M, Edelbauer H, Pankevych H, Boehm S. Autoinhibition of transmitter release from PC12 cells and sympathetic neurons through a P2Y receptor-mediated inhibition of voltage-gated Ca2+ channels. The European Journal of Neuroscience. 20: 2917-28. PMID 15579146 DOI: 10.1111/j.1460-9568.2004.03760.x  1
2003 Lechner SG, Mayer M, Boehm S. Activation of M1 muscarinic receptors triggers transmitter release from rat sympathetic neurons through an inhibition of M-type K+ channels. The Journal of Physiology. 553: 789-802. PMID 14555721 DOI: 10.1113/jphysiol.2003.052449  1
2003 Kubista H, Lechner SG, Wolf AM, Boehm S. Attenuation of the P2Y receptor-mediated control of neuronal Ca2+ channels in PC12 cells by antithrombotic drugs. British Journal of Pharmacology. 138: 343-50. PMID 12540525 DOI: 10.1038/sj.bjp.0705037  1
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