Kevin Staley - Publications

Harvard Medical School, Boston, MA, United States 

142 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Dzhala VI, Staley KJ. KCC2 chloride transport contributes to the termination of ictal epileptiform activity. Eneuro. PMID 33239270 DOI: 10.1523/ENEURO.0208-20.2020  1
2020 Soul JS, Bergin AM, Stopp C, Hayes B, Singh A, Fortuno CR, O'Reilly D, Krishnamoorthy K, Jensen FE, Rofeberg V, Dong M, Vinks AA, Wypij D, Staley KJ. A pilot randomized, controlled, double-blind trial of bumetanide to treat neonatal seizures Controlled bumetanide trial for neonatal seizures. Annals of Neurology. PMID 33201535 DOI: 10.1002/ana.25959  0.44
2019 Kramer MA, Ostrowski LM, Song DY, Thorn EL, Stoyell SM, Parnes M, Chinappen D, Xiao G, Eden UT, Staley KJ, Stufflebeam SM, Chu CJ. Scalp recorded spike ripples predict seizure risk in childhood epilepsy better than spikes. Brain : a Journal of Neurology. PMID 30907404 DOI: 10.1093/brain/awz059  0.84
2018 Jacob T, Lillis K, Wang Z, Swiercz W, Rahmati N, Staley K. A proposed mechanism for spontaneous transitions between interictal and ictal activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30446533 DOI: 10.1523/JNEUROSCI.0719-17.2018  1
2018 Blauwblomme T, Dzhala V, Staley K. Transient ischemia facilitates neuronal chloride accumulation and severity of seizures. Annals of Clinical and Translational Neurology. 5: 1048-1061. PMID 30250862 DOI: 10.1002/acn3.617  1
2018 Lillis KP, Staley KJ. Optogenetic dissection of ictogenesis: in search of a targeted anti-epileptic therapy. Journal of Neural Engineering. PMID 29536948 DOI: 10.1088/1741-2552/aab66a  1
2017 Glykys J, Dzhala V, Egawa K, Kahle KT, Delpire E, Staley K. Chloride Dysregulation, Seizures, and Cerebral Edema: A Relationship with Therapeutic Potential. Trends in Neurosciences. PMID 28431741 DOI: 10.1016/j.tins.2017.03.006  1
2017 Liu J, Saponjian Y, Mahoney MM, Staley KJ, Berdichevsky Y. Epileptogenesis in organotypic hippocampal cultures has limited dependence on culture medium composition. Plos One. 12: e0172677. PMID 28225808 DOI: 10.1371/journal.pone.0172677  1
2016 Berdichevsky Y, Saponjian Y, Park KI, Roach B, Pouliot W, Lu K, Swiercz W, Dudek FE, Staley KJ. Staged anticonvulsant screening for chronic epilepsy. Annals of Clinical and Translational Neurology. 3: 908-923. PMID 28097203 DOI: 10.1002/acn3.364  1
2016 Chu CJ, Chan A, Song D, Staley KJ, Stufflebeam SM, Kramer MA. A semi-automated method for rapid detection of ripple events on interictal voltage discharges in the scalp electroencephalogram. Journal of Neuroscience Methods. PMID 27988323 DOI: 10.1016/j.jneumeth.2016.12.009  0.84
2016 Song Y, Pimentel C, Walters K, Boller L, Ghiasvand S, Liu J, Staley KJ, Berdichevsky Y. Neuroprotective levels of IGF-1 exacerbate epileptogenesis after brain injury. Scientific Reports. 6: 32095. PMID 27561791 DOI: 10.1038/srep32095  1
2016 Glykys J, Staley KJ. Developmental Decrease of Neuronal Chloride Concentration Is Independent of Trauma in Thalamocortical Brain Slices. Plos One. 11: e0158012. PMID 27337272 DOI: 10.1371/journal.pone.0158012  1
2016 Kahle KT, Khanna AR, Duan J, Staley KJ, Delpire E, Poduri A. The KCC2 Cotransporter and Human Epilepsy: Getting Excited About Inhibition. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. PMID 27130838 DOI: 10.1177/1073858416645087  0.6
2015 Glykys J, Staley KJ. Diazepam effect during early neonatal development correlates with neuronal Cl(.). Annals of Clinical and Translational Neurology. 2: 1055-70. PMID 26734658 DOI: 10.1002/acn3.259  0.8
2015 Staley K, Ragan T. Runway disaster readiness. Jems : a Journal of Emergency Medical Services. 40: 36-9. PMID 26554179  0.32
2015 Park KI, Dzhala V, Saponjian Y, Staley KJ. What Elements of the Inflammatory System Are Necessary for Epileptogenesis In Vitro?(1,2). Eneuro. 2. PMID 26464976 DOI: 10.1523/ENEURO.0027-14.2015  1
2015 Pitkänen A, Lukasiuk K, Dudek FE, Staley KJ. Epileptogenesis. Cold Spring Harbor Perspectives in Medicine. 5. PMID 26385090 DOI: 10.1101/cshperspect.a022822  1
2015 Lillis KP, Wang Z, Mail M, Zhao GQ, Berdichevsky Y, Bacskai B, Staley KJ. Evolution of Network Synchronization during Early Epileptogenesis Parallels Synaptic Circuit Alterations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 9920-34. PMID 26156993 DOI: 10.1523/JNEUROSCI.4007-14.2015  1
2015 Staley K. Molecular mechanisms of epilepsy. Nature Neuroscience. 18: 367-72. PMID 25710839 DOI: 10.1038/nn.3947  1
2015 Dzhala V, Staley KJ. Acute and chronic efficacy of bumetanide in an in vitro model of posttraumatic epileptogenesis. Cns Neuroscience & Therapeutics. 21: 173-80. PMID 25495911 DOI: 10.1111/cns.12369  1
2015 Trevelyan AJ, Muldoon SF, Merricks EM, Racca C, Staley KJ. The role of inhibition in epileptic networks Journal of Clinical Neurophysiology. 32: 227-234. DOI: 10.1097/WNP.0000000000000160  1
2014 Glykys J, Dzhala V, Egawa K, Balena T, Saponjian Y, Kuchibhotla KV, Bacskai BJ, Kahle KT, Zeuthen T, Staley KJ. Response to comments on "Local impermeant anions establish the neuronal chloride concentration". Science (New York, N.Y.). 345: 1130. PMID 25190789 DOI: 10.1126/science.1253146  1
2014 Delpire E, Staley KJ. Novel determinants of the neuronal Cl(-) concentration. The Journal of Physiology. 592: 4099-114. PMID 25107928 DOI: 10.1113/jphysiol.2014.275529  1
2014 Heinemann U, Staley KJ. What is the clinical relevance of in vitro epileptiform activity? Advances in Experimental Medicine and Biology. 813: 25-41. PMID 25012364 DOI: 10.1007/978-94-017-8914-1_2  1
2014 Glykys J, Dzhala V, Egawa K, Balena T, Saponjian Y, Kuchibhotla KV, Bacskai BJ, Kahle KT, Zeuthen T, Staley KJ. Local impermeant anions establish the neuronal chloride concentration. Science (New York, N.Y.). 343: 670-5. PMID 24503855 DOI: 10.1126/science.1245423  1
2014 Polydoro M, Dzhala VI, Pooler AM, Nicholls SB, McKinney AP, Sanchez L, Pitstick R, Carlson GA, Staley KJ, Spires-Jones TL, Hyman BT. Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model. Acta Neuropathologica. 127: 257-70. PMID 24271788 DOI: 10.1007/s00401-013-1215-5  1
2014 Staley K, Dyhrfjeld-Johnsen J, Swiercz W, Dudek FE. Network Control Mechanisms-Synaptogenesis and Epilepsy Development Neuronal Networks in Brain Function, Cns Disorders, and Therapeutics. 207-213. DOI: 10.1016/B978-0-12-415804-7.00016-2  1
2013 O'Brien TJ, Ben-Menachem E, Bertram EH, Collins SD, Kokaia M, Lerche H, Klitgaard H, Staley KJ, Vaudano E, Walker MC, Simonato M. Proposal for a "phase II" multicenter trial model for preclinical new antiepilepsy therapy development. Epilepsia. 54: 70-4. PMID 23909855 DOI: 10.1111/epi.12300  1
2013 Galanopoulou AS, Kokaia M, Loeb JA, Nehlig A, Pitkänen A, Rogawski MA, Staley KJ, Whittemore VH, Dudek FE. Epilepsy therapy development: technical and methodologic issues in studies with animal models. Epilepsia. 54: 13-23. PMID 23909850 DOI: 10.1111/epi.12295  1
2013 Diao L, Hellier JL, Uskert-Newsom J, Williams PA, Staley KJ, Yee AS. Diphenytoin, riluzole and lidocaine: three sodium channel blockers, with different mechanisms of action, decrease hippocampal epileptiform activity. Neuropharmacology. 73: 48-55. PMID 23707481 DOI: 10.1016/j.neuropharm.2013.04.057  1
2013 Berdichevsky Y, Dryer AM, Saponjian Y, Mahoney MM, Pimentel CA, Lucini CA, Usenovic M, Staley KJ. PI3K-Akt signaling activates mTOR-mediated epileptogenesis in organotypic hippocampal culture model of post-traumatic epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9056-67. PMID 23699517 DOI: 10.1523/JNEUROSCI.3870-12.2013  1
2012 Seker E, Berdichevsky Y, Staley KJ, Yarmush ML. Microfabrication-compatible nanoporous gold foams as biomaterials for drug delivery. Advanced Healthcare Materials. 1: 172-6. PMID 23184720 DOI: 10.1002/adhm.201200002  1
2012 Staley K. Neonatal encephalopathy, MRI lesions, and later epilepsy: no harm, no foul? Epilepsy Currents / American Epilepsy Society. 12: 128-30. PMID 22936880 DOI: 10.5698/1535-7511-12.4.128  1
2012 Dobelis P, Staley KJ, Cooper DC. Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons. Plos One. 7: e41108. PMID 22848433 DOI: 10.1371/journal.pone.0041108  1
2012 Simonato M, Löscher W, Cole AJ, Dudek FE, Engel J, Kaminski RM, Loeb JA, Scharfman H, Staley KJ, Velíšek L, Klitgaard H. Finding a better drug for epilepsy: preclinical screening strategies and experimental trial design. Epilepsia. 53: 1860-7. PMID 22708847 DOI: 10.1111/j.1528-1167.2012.03541.x  1
2012 Lillis KP, Kramer MA, Mertz J, Staley KJ, White JA. Pyramidal cells accumulate chloride at seizure onset. Neurobiology of Disease. 47: 358-66. PMID 22677032 DOI: 10.1016/j.nbd.2012.05.016  1
2012 Dzhala V, Valeeva G, Glykys J, Khazipov R, Staley K. Traumatic alterations in GABA signaling disrupt hippocampal network activity in the developing brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4017-31. PMID 22442068 DOI: 10.1523/JNEUROSCI.5139-11.2012  1
2012 Sabolek HR, Swiercz WB, Lillis KP, Cash SS, Huberfeld G, Zhao G, Ste Marie L, Clemenceau S, Barsh G, Miles R, Staley KJ. A candidate mechanism underlying the variance of interictal spike propagation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3009-21. PMID 22378874 DOI: 10.1523/JNEUROSCI.5853-11.2012  1
2012 Galanopoulou AS, Buckmaster PS, Staley KJ, Moshé SL, Perucca E, Engel J, Löscher W, Noebels JL, Pitkänen A, Stables J, White HS, O'Brien TJ, Simonato M. Identification of new epilepsy treatments: issues in preclinical methodology. Epilepsia. 53: 571-82. PMID 22292566 DOI: 10.1111/j.1528-1167.2011.03391.x  1
2012 Berdichevsky Y, Dzhala V, Mail M, Staley KJ. Interictal spikes, seizures and ictal cell death are not necessary for post-traumatic epileptogenesis in vitro. Neurobiology of Disease. 45: 774-85. PMID 22115940 DOI: 10.1016/j.nbd.2011.11.001  1
2012 Seker E, Berdichevsky Y, Staley KJ, Yarmush ML. Nanoporous gold: A biomaterial for microfabricated drug-delivery platforms Materials Research Society Symposium Proceedings. 1415: 147-152. DOI: 10.1557/opl.2012.46  1
2011 Staley K. Carts, Horses, and Push-Pull Regulation of EGABA in Neonatal Seizures. Epilepsy Currents / American Epilepsy Society. 11: 205-8. PMID 22129766 DOI: 10.5698/1535-7511-11.6.205  1
2011 Dudek FE, Staley KJ. Seizure probability in animal models of acquired epilepsy: a perspective on the concept of the preictal state. Epilepsy Research. 97: 324-31. PMID 22094446 DOI: 10.1016/j.eplepsyres.2011.10.017  1
2011 Maa EH, Kahle KT, Walcott BP, Spitz MC, Staley KJ. Diuretics and epilepsy: will the past and present meet? Epilepsia. 52: 1559-69. PMID 21838793 DOI: 10.1111/j.1528-1167.2011.03203.x  1
2011 Vandeventer S, Studnek JR, Garrett JS, Ward SR, Staley K, Blackwell T. The association between ambulance hospital turnaround times and patient acuity, destination hospital, and time of day. Prehospital Emergency Care : Official Journal of the National Association of Ems Physicians and the National Association of State Ems Directors. 15: 366-70. PMID 21480775 DOI: 10.3109/10903127.2011.561412  0.32
2011 Köhling R, Staley K. Network mechanisms for fast ripple activity in epileptic tissue. Epilepsy Research. 97: 318-23. PMID 21470826 DOI: 10.1016/j.eplepsyres.2011.03.006  1
2011 Dudek FE, Staley KJ. The time course of acquired epilepsy: implications for therapeutic intervention to suppress epileptogenesis. Neuroscience Letters. 497: 240-6. PMID 21458536 DOI: 10.1016/j.neulet.2011.03.071  1
2011 Staley KJ, White A, Dudek FE. Interictal spikes: harbingers or causes of epilepsy? Neuroscience Letters. 497: 247-50. PMID 21458535 DOI: 10.1016/j.neulet.2011.03.070  1
2011 Kahle KT, Walcott BP, Staley KJ. Resolution of headache and papilledema in idiopathic intracranial hypertension associated with inhibition of Na+-K+-2Cl- cotransport. Journal of Child Neurology. 26: 205-8. PMID 21285039 DOI: 10.1177/0883073810391264  1
2011 Kahle KT, Staley KJ. Response to "a claim for caution in the use of promising bumetanide to treat neonatal seizures" Journal of Child Neurology. 26: 658-659. DOI: 10.1177/0883073811401400  1
2011 Berdichevsky Y, Staley KJ. Multiple-compartment chip for parallel recordings of epileptic activity from organotypic cultures 2011 5th International Ieee/Embs Conference On Neural Engineering, Ner 2011. 572-575. DOI: 10.1109/NER.2011.5910613  1
2010 Dyhrfjeld-Johnsen J, Berdichevsky Y, Swiercz W, Sabolek H, Staley KJ. Interictal spikes precede ictal discharges in an organotypic hippocampal slice culture model of epileptogenesis. Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society. 27: 418-24. PMID 21076333 DOI: 10.1097/WNP.0b013e3181fe0709  1
2010 Staley K. Stroke: recovery inhibitors under attack. Nature. 468: 176-7. PMID 21068818 DOI: 10.1038/468176a  1
2010 Shin JH, Smith D, Swiercz W, Staley K, Rickard JT, Montero J, Kurgan LA, Cios KJ. Recognition of partially occluded and rotated images with a network of spiking neurons. Ieee Transactions On Neural Networks / a Publication of the Ieee Neural Networks Council. 21: 1697-709. PMID 21047704 DOI: 10.1109/TNN.2010.2050600  1
2010 Studnek JR, Thestrup L, Vandeventer S, Ward SR, Staley K, Garvey L, Blackwell T. The association between prehospital endotracheal intubation attempts and survival to hospital discharge among out-of-hospital cardiac arrest patients. Academic Emergency Medicine : Official Journal of the Society For Academic Emergency Medicine. 17: 918-25. PMID 20836771 DOI: 10.1111/j.1553-2712.2010.00827.x  0.32
2010 Dzhala VI, Kuchibhotla KV, Glykys JC, Kahle KT, Swiercz WB, Feng G, Kuner T, Augustine GJ, Bacskai BJ, Staley KJ. Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11745-61. PMID 20810895 DOI: 10.1523/JNEUROSCI.1769-10.2010  1
2010 Dudek FE, Ekstrand JJ, Staley KJ. Is neuronal death necessary for acquired epileptogenesis in the immature brain? Epilepsy Currents / American Epilepsy Society. 10: 95-9. PMID 20697505 DOI: 10.1111/j.1535-7511.2010.01369.x  1
2010 Dredge DC, Parsons EC, Carter LP, Staley KJ. Anticonvulsant hypersensitivity syndrome treated with intravenous immunoglobulin. Pediatric Neurology. 43: 65-9. PMID 20682208 DOI: 10.1016/j.pediatrneurol.2010.03.010  1
2010 Dudek FE, Pouliot WA, Rossi CA, Staley KJ. The effect of the cannabinoid-receptor antagonist, SR141716, on the early stage of kainate-induced epileptogenesis in the adult rat. Epilepsia. 51: 126-30. PMID 20618417 DOI: 10.1111/j.1528-1167.2010.02626.x  1
2010 Berdichevsky Y, Staley KJ, Yarmush ML. Building and manipulating neural pathways with microfluidics. Lab On a Chip. 10: 999-1004. PMID 20358106 DOI: 10.1039/b922365g  1
2010 Seker E, Berdichevsky Y, Begley MR, Reed ML, Staley KJ, Yarmush ML. The fabrication of low-impedance nanoporous gold multiple-electrode arrays for neural electrophysiology studies. Nanotechnology. 21: 125504. PMID 20203356 DOI: 10.1088/0957-4484/21/12/125504  1
2010 Kadam SD, White AM, Staley KJ, Dudek FE. Continuous electroencephalographic monitoring with radio-telemetry in a rat model of perinatal hypoxia-ischemia reveals progressive post-stroke epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 404-15. PMID 20053921 DOI: 10.1523/JNEUROSCI.4093-09.2010  1
2010 White A, Williams PA, Hellier JL, Clark S, Dudek FE, Staley KJ. EEG spike activity precedes epilepsy after kainate-induced status epilepticus. Epilepsia. 51: 371-83. PMID 19845739 DOI: 10.1111/j.1528-1167.2009.02339.x  1
2010 Kahle KT, Staley KJ. A treatment paradigm for neonatal seizures based on the ontogeny of neuronal chloride/cation cotransporter expression in the human cortex Epilepsia. 51: 89. DOI: 10.1111/j.1528-1167.2010.02875.x  1
2010 Dudek FE, Staley KJ. Circuit mechanisms of acquired epileptogenesis Epilepsia. 51: 38. DOI: 10.1111/j.1528-1167.2010.02824.x  1
2010 Staley K. GABAA Receptors and Disease Encyclopedia of Neuroscience. 447-452. DOI: 10.1016/B978-008045046-9.01237-7  1
2010 Kahle KT, Staley KJ. Cation-chloride cotransporters as pharmacological targets in the treatment of epilepsy Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. 489-500. DOI: 10.1016/B978-0-12-374373-2.00024-8  1
2009 Glykys J, Dzhala VI, Kuchibhotla KV, Feng G, Kuner T, Augustine G, Bacskai BJ, Staley KJ. Differences in cortical versus subcortical GABAergic signaling: a candidate mechanism of electroclinical uncoupling of neonatal seizures. Neuron. 63: 657-72. PMID 19755108 DOI: 10.1016/j.neuron.2009.08.022  1
2009 Kahle KT, Simard JM, Staley KJ, Nahed BV, Jones PS, Sun D. Molecular mechanisms of ischemic cerebral edema: role of electroneutral ion transport. Physiology (Bethesda, Md.). 24: 257-65. PMID 19675357 DOI: 10.1152/physiol.00015.2009  1
2009 Dulla CG, Frenguelli BG, Staley KJ, Masino SA. Intracellular acidification causes adenosine release during states of hyperexcitability in the hippocampus. Journal of Neurophysiology. 102: 1984-93. PMID 19625534 DOI: 10.1152/jn.90695.2008  1
2009 Kahle KT, Barnett SM, Sassower KC, Staley KJ. Decreased seizure activity in a human neonate treated with bumetanide, an inhibitor of the Na(+)-K(+)-2Cl(-) cotransporter NKCC1. Journal of Child Neurology. 24: 572-6. PMID 19406757 DOI: 10.1177/0883073809333526  1
2009 Williams PA, White AM, Clark S, Ferraro DJ, Swiercz W, Staley KJ, Dudek FE. Development of spontaneous recurrent seizures after kainate-induced status epilepticus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2103-12. PMID 19228963 DOI: 10.1523/JNEUROSCI.0980-08.2009  1
2009 Staley KJ, Anderson AE. Hyperactive interneurons impair learning in a neurofibromatosis model. Nature Neuroscience. 12: 8-10. PMID 19107143 DOI: 10.1038/nn0109-8  1
2009 Berdichevsky Y, Sabolek H, Levine JB, Staley KJ, Yarmush ML. Microfluidics and multielectrode array-compatible organotypic slice culture method. Journal of Neuroscience Methods. 178: 59-64. PMID 19100768 DOI: 10.1016/j.jneumeth.2008.11.016  1
2009 Frey LC, Hellier J, Unkart C, Lepkin A, Howard A, Hasebroock K, Serkova N, Liang L, Patel M, Soltesz I, Staley K. A novel apparatus for lateral fluid percussion injury in the rat. Journal of Neuroscience Methods. 177: 267-72. PMID 19022291 DOI: 10.1016/j.jneumeth.2008.10.022  1
2009 Hellier JL, White A, Williams PA, Dudek FE, Staley KJ. NMDA receptor-mediated long-term alterations in epileptiform activity in experimental chronic epilepsy. Neuropharmacology. 56: 414-21. PMID 18930747 DOI: 10.1016/j.neuropharm.2008.09.009  1
2009 Shin JH, Smith D, Swiniarski R, Dudek FE, White A, Staley K, Cios KJ. Analysis of EEG epileptic signals with rough sets and support vector machines Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5651: 325-334. DOI: 10.1007/978-3-642-02976-9_45  1
2008 Staley KJ, Sims KB, Grant PE, Hedley-Whyte ET. Case records of the Massachusetts General Hospital. Case 28-2008. An 8-day-old infant with congenital deafness, lethargy, and hypothermia. The New England Journal of Medicine. 359: 1156-67. PMID 18784106 DOI: 10.1056/NEJMcpc0804642  1
2008 Kahle KT, Staley KJ, Nahed BV, Gamba G, Hebert SC, Lifton RP, Mount DB. Roles of the cation-chloride cotransporters in neurological disease. Nature Clinical Practice. Neurology. 4: 490-503. PMID 18769373 DOI: 10.1038/ncpneuro0883  1
2008 Kahle KT, Staley KJ. The bumetanide-sensitive Na-K-2Cl cotransporter NKCC1 as a potential target of a novel mechanism-based treatment strategy for neonatal seizures. Neurosurgical Focus. 25: E22. PMID 18759624 DOI: 10.3171/FOC/2008/25/9/E22  1
2008 Kahle KT, Staley K. Altered neuronal chloride homeostasis and excitatory GABAergic signaling in human temporal lobe epilepsy. Epilepsy Currents / American Epilepsy Society. 8: 51-3. PMID 18330470 DOI: 10.1111/j.1535-7511.2008.00235.x  0.6
2008 Jarrett SG, Liang LP, Hellier JL, Staley KJ, Patel M. Mitochondrial DNA damage and impaired base excision repair during epileptogenesis. Neurobiology of Disease. 30: 130-8. PMID 18295498 DOI: 10.1016/j.nbd.2007.12.009  1
2008 Dudek FE, Bertram EH, Staley KJ. Antiepileptogenesis Therapy with Levetiracetam: Data from Kindling versus Status Epilepticus Models. Epilepsy Currents / American Epilepsy Society. 8: 28-30. PMID 18265888 DOI: 10.1111/j.1535-7511.2007.00226.x  1
2008 Brumback AC, Staley KJ. Thermodynamic regulation of NKCC1-mediated Cl- cotransport underlies plasticity of GABA(A) signaling in neonatal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1301-12. PMID 18256250 DOI: 10.1523/JNEUROSCI.3378-07.2008  1
2008 Dzhala VI, Brumback AC, Staley KJ. Bumetanide enhances phenobarbital efficacy in a neonatal seizure model. Annals of Neurology. 63: 222-35. PMID 17918265 DOI: 10.1002/ana.21229  1
2008 Staley K, Swiercz W, Cios KJ. Validating Models of Epilepsy Computational Neuroscience in Epilepsy. 43-47. DOI: 10.1016/B978-012373649-9.50007-7  1
2008 Soltesz I, Staley K. Introduction Computational Neuroscience in Epilepsy. xv-xix. DOI: 10.1016/B978-012373649-9.50003-X  1
2008 Soltesz I, Staley K. Computational Neuroscience in Epilepsy Computational Neuroscience in Epilepsy 1
2007 Williams PA, Hellier JL, White AM, Staley KJ, Dudek FE. Development of spontaneous seizures after experimental status epilepticus: implications for understanding epileptogenesis. Epilepsia. 48: 157-63. PMID 17910596 DOI: 10.1111/j.1528-1167.2007.01304.x  1
2007 Staley KJ. Neurons skip a beat during fast ripples. Neuron. 55: 828-30. PMID 17880888 DOI: 10.1016/j.neuron.2007.09.005  1
2007 Hellier JL, Grosshans DR, Coultrap SJ, Jones JP, Dobelis P, Browning MD, Staley KJ. NMDA receptor trafficking at recurrent synapses stabilizes the state of the CA3 network. Journal of Neurophysiology. 98: 2818-26. PMID 17728388 DOI: 10.1152/jn.00346.2007  1
2007 Dudek FE, Staley KJ. How does the balance of excitation and inhibition shift during epileptogenesis? Epilepsy Currents / American Epilepsy Society. 7: 86-8. PMID 17520084 DOI: 10.1111/j.1535-7511.2007.00181.x  1
2007 Schuyler R, White A, Staley K, Cios KJ. Epileptic seizure detection. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 26: 74-82. PMID 17441611 DOI: 10.1109/MEMB.2007.335592  1
2007 Swiercz W, Cios K, Hellier J, Yee A, Staley K. Effects of synaptic depression and recovery on synchronous network activity. Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society. 24: 165-74. PMID 17414972 DOI: 10.1097/WNP.0b013e318033756f  1
2007 Holmes GL, Stafstrom CE. Tuberous sclerosis complex and epilepsy: recent developments and future challenges. Epilepsia. 48: 617-30. PMID 17386056 DOI: 10.1111/j.1528-1167.2007.01035.x  1
2007 Jones J, Stubblefield EA, Benke TA, Staley KJ. Desynchronization of glutamate release prolongs synchronous CA3 network activity. Journal of Neurophysiology. 97: 3812-8. PMID 17344368 DOI: 10.1152/jn.01310.2006  1
2007 Dudek FE, Staley KJ. Analysis of eleptiogenesis with EEG-radiotelemetry in animal models of epilepsy Proceedings of the 3rd International Ieee Embs Conference On Neural Engineering. 241-243. DOI: 10.1109/CNE.2007.369656  1
2007 Staley KJ, Dudek FE. Analysis of epileptic neural networks based on the temporal distribution of interictal spikes Proceedings of the 3rd International Ieee Embs Conference On Neural Engineering. 237-240. DOI: 10.1109/CNE.2007.369655  1
2006 Dudek FE, Staley KJ. Laser scanning photostimulation: new evidence for enhanced recurrent excitation in a model of posttraumatic epilepsy. Epilepsy Currents / American Epilepsy Society. 6: 215-6. PMID 17260064 DOI: 10.1111/j.1535-7511.2006.00150.x  1
2006 Staley KJ, Dudek FE. Interictal spikes and epileptogenesis. Epilepsy Currents / American Epilepsy Society. 6: 199-202. PMID 17260059 DOI: 10.1111/j.1535-7511.2006.00145.x  1
2006 Staley KJ, Huguenard JR. A thalamic sleep tonic. Epilepsy Currents / American Epilepsy Society. 6: 164-6. PMID 17260047 DOI: 10.1111/j.1535-7511.2006.00133.x  0.92
2006 Soltesz I, Staley K. High times for memory: cannabis disrupts temporal coordination among hippocampal neurons. Nature Neuroscience. 9: 1461-3. PMID 17128279 DOI: 10.1038/nn1206-1461  1
2006 Prescott C, Weeks AM, Staley KJ, Partin KM. Kynurenic acid has a dual action on AMPA receptor responses. Neuroscience Letters. 402: 108-12. PMID 16644124 DOI: 10.1016/j.neulet.2006.03.051  1
2006 Williams P, White A, Ferraro D, Clark S, Staley K, Dudek FE. The use of radiotelemetry to evaluate electrographic seizures in rats with kainate-induced epilepsy. Journal of Neuroscience Methods. 155: 39-48. PMID 16564574 DOI: 10.1016/j.jneumeth.2005.12.035  1
2006 Swiercz W, Cios KJ, Staley K, Kurgan L, Accurso F, Sagel S. A new synaptic plasticity rule for networks of spiking neurons. Ieee Transactions On Neural Networks / a Publication of the Ieee Neural Networks Council. 17: 94-105. PMID 16526479 DOI: 10.1109/TNN.2005.860834  0.32
2006 White AM, Williams PA, Ferraro DJ, Clark S, Kadam SD, Dudek FE, Staley KJ. Efficient unsupervised algorithms for the detection of seizures in continuous EEG recordings from rats after brain injury. Journal of Neuroscience Methods. 152: 255-66. PMID 16337006 DOI: 10.1016/j.jneumeth.2005.09.014  1
2005 Dudek FE, Staley KJ. Chronic cortical injury and epileptogensis: a possible role for intracellular chloride homeostasis. Epilepsy Currents / American Epilepsy Society. 5: 239-40. PMID 16372061 DOI: 10.1111/j.1535-7511.2005.00075.x  1
2005 Dulla CG, Dobelis P, Pearson T, Frenguelli BG, Staley KJ, Masino SA. Adenosine and ATP link PCO2 to cortical excitability via pH. Neuron. 48: 1011-23. PMID 16364904 DOI: 10.1016/j.neuron.2005.11.009  1
2005 Dzhala VI, Talos DM, Sdrulla DA, Brumback AC, Mathews GC, Benke TA, Delpire E, Jensen FE, Staley KJ. NKCC1 transporter facilitates seizures in the developing brain. Nature Medicine. 11: 1205-13. PMID 16227993 DOI: 10.1038/nm1301  1
2005 Staley K, Hellier JL, Dudek FE. Do interictal spikes drive epileptogenesis? The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 11: 272-6. PMID 16061513 DOI: 10.1177/1073858405278239  1
2005 Staley K, Scharfman H. A woman's prerogative. Nature Neuroscience. 8: 697-9. PMID 15917829 DOI: 10.1038/nn0605-697  0.32
2004 Dzhala VI, Staley KJ. Mechanisms of fast ripples in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8896-906. PMID 15470156 DOI: 10.1523/JNEUROSCI.3112-04.2004  1
2004 Staley K. Neuroscience. Epileptic neurons go wireless. Science (New York, N.Y.). 305: 482-3. PMID 15273382 DOI: 10.1126/science.1101133  1
2004 Staley KJ. Role of the depolarizing GABA response in epilepsy. Advances in Experimental Medicine and Biology. 548: 104-9. PMID 15250589  1
2003 Staley K. Salt and wounds: a new mechanism for neuropathic pain. Nature Medicine. 9: 1110-1. PMID 12949519 DOI: 10.1038/nm0903-1110  1
2003 Dzhala VI, Staley KJ. Transition from interictal to ictal activity in limbic networks in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7873-80. PMID 12944517  1
2003 Dzhala VI, Staley KJ. Excitatory actions of endogenously released GABA contribute to initiation of ictal epileptiform activity in the developing hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1840-6. PMID 12629188  1
2003 Yee AS, Longacher JM, Staley KJ. Convulsant and anticonvulsant effects on spontaneous CA3 population bursts. Journal of Neurophysiology. 89: 427-41. PMID 12522191 DOI: 10.1152/jn.00594.2002  1
2002 Dudek FE, Staley KJ, Sutula TP. The search for animal models of epileptogenesis and pharmacoresistance: are there biologic barriers to simple validation strategies? Epilepsia. 43: 1275-7. PMID 12423376 DOI: 10.1046/j.1528-1157.2002.35102.x  1
2002 Dudek FE, Hellier JL, Williams PA, Ferraro DJ, Staley KJ. The course of cellular alterations associated with the development of spontaneous seizures after status epilepticus. Progress in Brain Research. 135: 53-65. PMID 12143370 DOI: 10.1016/S0079-6123(02)35007-6  1
2001 Staley KJ, Bains JS, Yee A, Hellier J, Longacher JM. Statistical model relating CA3 burst probability to recovery from burst-induced depression at recurrent collateral synapses. Journal of Neurophysiology. 86: 2736-47. PMID 11731533  1
2001 Staley K, Smith R. A new form of feedback at the GABA(A) receptor. Nature Neuroscience. 4: 674-6. PMID 11426214 DOI: 10.1038/89439  1
2000 Smith RL, Traul DL, Schaack J, Clayton GH, Staley KJ, Wilcox CL. Characterization of promoter function and cell-type-specific expression from viral vectors in the nervous system. Journal of Virology. 74: 11254-61. PMID 11070024 DOI: 10.1128/JVI.74.23.11254-11261.2000  1
1999 Staley KJ, Proctor WR. Modulation of mammalian dendritic GABA(A) receptor function by the kinetics of Cl- and HCO3- transport. The Journal of Physiology. 519: 693-712. PMID 10457084 DOI: 10.1111/j.1469-7793.1999.0693n.x  1
1999 Staley KJ. Quantal GABA release: noise or not? Nature Neuroscience. 2: 494-5. PMID 10448209 DOI: 10.1038/9139  1
1999 Bains JS, Longacher JM, Staley KJ. Reciprocal interactions between CA3 network activity and strength of recurrent collateral synapses. Nature Neuroscience. 2: 720-6. PMID 10412061 DOI: 10.1038/11184  1
1998 Staley KJ, Longacher M, Bains JS, Yee A. Presynaptic modulation of CA3 network activity. Nature Neuroscience. 1: 201-9. PMID 10195144 DOI: 10.1038/651  1
1998 Clayton GH, Staley KJ, Wilcox CL, Owens GC, Smith RL. Developmental expression of C1C-2 in the rat nervous system. Brain Research. Developmental Brain Research. 108: 307-18. PMID 9693808 DOI: 10.1016/S0165-3806(98)00045-5  1
1996 Staley K, Smith R, Schaack J, Wilcox C, Jentsch TJ. Alteration of GABAA receptor function following gene transfer of the CLC-2 chloride channel. Neuron. 17: 543-51. PMID 8816717 DOI: 10.1016/S0896-6273(00)80186-5  1
1995 Smith RL, Clayton GH, Wilcox CL, Escudero KW, Staley KJ. Differential expression of an inwardly rectifying chloride conductance in rat brain neurons: a potential mechanism for cell-specific modulation of postsynaptic inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4057-67. PMID 7751965  1
1995 Staley KJ, Soldo BL, Proctor WR. Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors. Science (New York, N.Y.). 269: 977-81. PMID 7638623  1
1994 Staley K. The role of an inwardly rectifying chloride conductance in postsynaptic inhibition. Journal of Neurophysiology. 72: 273-84. PMID 7965011  1
1994 Mody I, Staley KJ. Cell properties in the epileptic hippocampus. Hippocampus. 4: 275-80. PMID 7531092 DOI: 10.1002/hipo.450040309  1
1992 Staley KJ, Otis TS, Mody I. Membrane properties of dentate gyrus granule cells: comparison of sharp microelectrode and whole-cell recordings. Journal of Neurophysiology. 67: 1346-58. PMID 1597717  1
1992 Staley KJ, Mody I. Shunting of excitatory input to dentate gyrus granule cells by a depolarizing GABAA receptor-mediated postsynaptic conductance. Journal of Neurophysiology. 68: 197-212. PMID 1381418  1
1992 Mody I, Otis TS, Staley KJ, Köhr G. The balance between excitation and inhibition in dentate granule cells and its role in epilepsy. Epilepsy Research. Supplement. 9: 331-9. PMID 1337447  1
1992 Mody I, Köhr G, Otis TS, Staley KJ. The electrophysiology of dentate gyrus granule cells in whole-cell recordings. Epilepsy Research. Supplement. 7: 159-68. PMID 1334661  1
1992 Staley K. Enhancement of the excitatory actions of GABA by barbiturates and benzodiazepines. Neuroscience Letters. 146: 105-7. PMID 1282225 DOI: 10.1016/0304-3940(92)90183-8  1
1991 Staley K, Iragui VJ. Somatosensory dysfunction in cystic fibrosis. European Neurology. 31: 77-81. PMID 2044620  1
1991 Staley KJ, Mody I. Integrity of perforant path fibers and the frequency of action potential independent excitatory and inhibitory synaptic events in dentate gyrus granule cells. Synapse (New York, N.Y.). 9: 219-24. PMID 1837962 DOI: 10.1002/syn.890090308  1
1991 Otis TS, Staley KJ, Mody I. Perpetual inhibitory activity in mammalian brain slices generated by spontaneous GABA release. Brain Research. 545: 142-50. PMID 1650273 DOI: 10.1016/0006-8993(91)91280-E  1
1990 Staley K, Iragui V, Spitz M. The human fetal auditory evoked potential. Electroencephalography and Clinical Neurophysiology. 77: 1-5. PMID 1688780 DOI: 10.1016/0168-5597(90)90011-2  1
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