| Year |
Citation |
Score |
| 2024 |
Toddes C, Lefevre EM, Retzlaff CL, Zugschwert L, Khan S, Myhre E, Gauthier EA, Fernandez de Velasco EM, Kieffer BL, Rothwell PE. Mu opioid receptor expression by nucleus accumbens inhibitory interneurons promotes affiliative social behavior. Biorxiv : the Preprint Server For Biology. PMID 39553981 DOI: 10.1101/2024.10.28.620729 |
0.429 |
|
| 2024 |
Fer M, Amalric C, Arban R, Baron L, Ben Hamida S, Breh-Schlanser P, Cui Y, Darcq E, Eickmeier C, Faye V, Franchet C, Frauli M, Halter C, Heyer M, Hoenke C, ... ... Kieffer BL, et al. Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for Mouse Studies. Journal of Medicinal Chemistry. PMID 38949964 DOI: 10.1021/acs.jmedchem.4c00665 |
0.695 |
|
| 2024 |
Smith ACW, Ghoshal S, Centanni SW, Heyer MP, Corona A, Wills L, Andraka E, Lei Y, O'Connor RM, Caligiuri SPB, Khan S, Beaumont K, Sebra RP, Kieffer BL, Winder DG, et al. A master regulator of opioid reward in the ventral prefrontal cortex. Science (New York, N.Y.). 384: eadn0886. PMID 38843332 DOI: 10.1126/science.adn0886 |
0.432 |
|
| 2024 |
Chaudun F, Python L, Liu Y, Hiver A, Cand J, Kieffer BL, Valjent E, Lüscher C. Distinct µ-opioid ensembles trigger positive and negative fentanyl reinforcement. Nature. PMID 38778097 DOI: 10.1038/s41586-024-07440-x |
0.449 |
|
| 2024 |
Ozdemir D, Meyer J, Kieffer BL, Darcq E. Model of negative affect induced by withdrawal from acute and chronic morphine administration in male mice. Scientific Reports. 14: 9767. PMID 38684914 DOI: 10.1038/s41598-024-60759-3 |
0.704 |
|
| 2024 |
Darcq E, Kieffer BL. Neuroscience and addiction research: current advances and perspectives. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 38492013 DOI: 10.1007/s00702-024-02763-5 |
0.578 |
|
| 2023 |
Sourty M, Champagnol-Di Liberti C, Nasseef MT, Welsch L, Noblet V, Darcq E, Kieffer BL. Chronic morphine leaves a durable fingerprint on whole brain functional connectivity. Biological Psychiatry. PMID 38104648 DOI: 10.1016/j.biopsych.2023.12.007 |
0.809 |
|
| 2023 |
Sourty M, Nasseef MT, Champagnol-Di Liberti C, Mondino M, Noblet V, Parise EM, Markovic T, Browne CJ, Darcq E, Nestler EJ, Kieffer BL. Manipulating ΔFOSB in D1-type Medium Spiny Neurons of the nucleus accumbens reshapes whole brain functional connectivity. Biological Psychiatry. PMID 37517704 DOI: 10.1016/j.biopsych.2023.07.013 |
0.798 |
|
| 2023 |
Welsch L, Colantonio E, Falconnier C, Champagnol-DiLiberti C, Allain F, Ben Hamida S, Darcq E, Lutz PE, Kieffer BL. Mu opioid receptor-positive neurons in the dorsal raphe nucleus are impaired by morphine abstinence. Biological Psychiatry. PMID 37393045 DOI: 10.1016/j.biopsych.2023.06.024 |
0.8 |
|
| 2023 |
Allain F, Ehrlich AT, McNicholas M, Gross F, Ma W, Kieffer BL, Darcq E. Chronic tianeptine induces tolerance in analgesia and hyperlocomotion via mu-opioid receptor activation in mice. Frontiers in Psychiatry. 14: 1186397. PMID 37287667 DOI: 10.3389/fpsyt.2023.1186397 |
0.837 |
|
| 2023 |
Welsch L, Colantonio E, Frison M, Johnson DA, McClain SP, Mathis V, Banghart MR, Ben Hamida S, Darcq E, Kieffer BL. Mu opioid receptors-expressing neurons in the dorsal raphe nucleus are involved in reward processing and affective behaviors. Biological Psychiatry. PMID 37285896 DOI: 10.1016/j.biopsych.2023.05.019 |
0.722 |
|
| 2023 |
Ozdemir D, Allain F, Kieffer BL, Darcq E. Advances in the characterization of negative affect caused by acute and protracted opioid withdrawal using animal models. Neuropharmacology. 232: 109524. PMID 37003572 DOI: 10.1016/j.neuropharm.2023.109524 |
0.705 |
|
| 2023 |
Rahman MT, Decker AM, Ben Hamida S, Perrey DA, Chaminda Lakmal HH, Maitra R, Darcq E, Kieffer BL, Jin C. Improvement of the Metabolic Stability of GPR88 Agonist RTI-13951-33: Design, Synthesis, and Biological Evaluation. Journal of Medicinal Chemistry. PMID 36749855 DOI: 10.1021/acs.jmedchem.2c01983 |
0.678 |
|
| 2023 |
Bossert JM, Mejias-Aponte CA, Saunders T, Altidor L, Emery M, Fredriksson I, Batista A, Claypool SM, Caldwell KE, Reiner DJ, Chow JJ, Foltz M, Kumar V, Seasholtz A, Hughes E, ... ... Kieffer BL, et al. Effect of selective lesions of nucleus accumbens µ-opioid receptor-expressing cells on heroin self-administration in male and female rats: a study with novel knock-in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36717230 DOI: 10.1523/JNEUROSCI.2049-22.2023 |
0.354 |
|
| 2022 |
Decker AM, Rahman MT, Kormos CM, Hesk D, Darcq E, Kieffer BL, Jin C. Synthesis and pharmacological validation of a novel radioligand for the orphan GPR88 receptor. Bioorganic & Medicinal Chemistry Letters. 80: 129120. PMID 36587872 DOI: 10.1016/j.bmcl.2022.129120 |
0.647 |
|
| 2022 |
Ehrlich AT, Couvineau P, Schamiloglu S, Wojcik S, Da Fonte D, Mezni A, von Zastrow M, Bender KJ, Bouvier M, Kieffer BL. Visualization of real-time receptor endocytosis in dopamine neurons enabled by NTSR1-Venus knock-in mice. Frontiers in Cellular Neuroscience. 16: 1076599. PMID 36523815 DOI: 10.3389/fncel.2022.1076599 |
0.351 |
|
| 2022 |
Bailly J, Allain F, Schwartz E, Tirel C, Dupuy C, Petit F, Diana MA, Darcq E, Kieffer BL. Habenular Neurons Expressing Mu Opioid Receptors Promote Negative Affect in a Projection-Specific Manner. Biological Psychiatry. PMID 36496267 DOI: 10.1016/j.biopsych.2022.09.013 |
0.732 |
|
| 2022 |
Darcq E, Nouel D, Hernandez G, Pokinko M, Ash P, Moquin L, Gratton A, Kieffer B, Flores C. Reduced dopamine release in Dcc haploinsufficiency male mice abolishes the rewarding effects of cocaine but not those of morphine and ethanol. Psychopharmacology. PMID 36471064 DOI: 10.1007/s00213-022-06288-1 |
0.639 |
|
| 2022 |
Allain F, Carter M, Dumas S, Darcq E, Kieffer BL. The mu opioid receptor and the orphan receptor GPR151 contribute to social reward in the habenula. Scientific Reports. 12: 20234. PMID 36424418 DOI: 10.1038/s41598-022-24395-z |
0.697 |
|
| 2022 |
Ben Hamida S, Carter M, Darcq E, Sourty M, Rahman MT, Decker AM, Jin C, Kieffer BL. The GPR88 agonist RTI-13951-33 reduces alcohol drinking and seeking in mice. Addiction Biology. 27: e13227. PMID 36301207 DOI: 10.1111/adb.13227 |
0.644 |
|
| 2022 |
Ben Hamida S, Sengupta SM, Clarke E, McNicholas M, Moroncini E, Darcq E, Ter-Stepanian M, Fortier MÈ, Grizenko N, Joober R, Kieffer BL. The orphan receptor GPR88 controls impulsivity and is a risk factor for Attention-Deficit/Hyperactivity Disorder. Molecular Psychiatry. PMID 36075963 DOI: 10.1038/s41380-022-01738-w |
0.788 |
|
| 2022 |
Posa L, De Gregorio D, He Q, Lopez-Canul M, Darcq E, Rullo L, Pearl-Dowler L, Luongo L, Candeletti S, Romualdi P, Kieffer BL, Gobbi G. Supraspinal melatonin MT receptor agonism alleviates pain via a neural circuit that recruits mu opioid receptors. Journal of Pineal Research. PMID 35996205 DOI: 10.1111/jpi.12825 |
0.848 |
|
| 2022 |
Zamfir M, Sharif B, Locke S, Ehrlich AT, Ochandarena NE, Scherrer G, Ribeiro-da-Silva A, Kieffer BL, Séguéla P. Distinct and sex-specific expression of mu opioid receptors in anterior cingulate and somatosensory S1 cortical areas. Pain. PMID 35973045 DOI: 10.1097/j.pain.0000000000002751 |
0.686 |
|
| 2021 |
Han J, Andreu V, Langreck C, Pekarskaya EA, Grinnell SG, Allain F, Magalong V, Pintar J, Kieffer BL, Harris AZ, Javitch JA, Hen R, Nautiyal KM. Mu opioid receptors on hippocampal GABAergic interneurons are critical for the antidepressant effects of tianeptine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34593976 DOI: 10.1038/s41386-021-01192-2 |
0.39 |
|
| 2021 |
Ehrlich AT, Semache M, Couvineau P, Wojcik S, Kobayashi H, Thelen M, Gross F, Hogue M, Le Gouill C, Darcq E, Bouvier M, Kieffer BL. Ackr3-Venus knock-in mouse lights up brain vasculature. Molecular Brain. 14: 151. PMID 34583741 DOI: 10.1186/s13041-021-00862-y |
0.704 |
|
| 2021 |
Rahman MT, Decker AM, Laudermilk L, Maitra R, Ma W, Ben Hamida S, Darcq E, Kieffer BL, Jin C. Evaluation of Amide Bioisosteres Leading to 1,2,3-Triazole Containing Compounds as GPR88 Agonists: Design, Synthesis, and Structure-Activity Relationship Studies. Journal of Medicinal Chemistry. PMID 34387471 DOI: 10.1021/acs.jmedchem.1c01075 |
0.667 |
|
| 2021 |
Karatas M, Noblet V, Nasseef MT, Bienert T, Reisert M, Hennig J, Yalcin I, Kieffer BL, von Elverfeldt D, Harsan LA. Mapping the living mouse brain neural architecture: strain-specific patterns of brain structural and functional connectivity. Brain Structure & Function. PMID 33635426 DOI: 10.1007/s00429-020-02190-8 |
0.774 |
|
| 2021 |
Lutz PE, Almeida D, Filliol D, Jollant F, Kieffer BL, Turecki G. Increased functional coupling of the mu opioid receptor in the anterior insula of depressed individuals. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33531622 DOI: 10.1038/s41386-021-00974-y |
0.676 |
|
| 2021 |
Nasseef MT, Ma W, Singh JP, Dozono N, Lançon K, Séguéla P, Darcq E, Ueda H, Kieffer BL. Chronic generalized pain disrupts whole brain functional connectivity in mice. Brain Imaging and Behavior. PMID 33428113 DOI: 10.1007/s11682-020-00438-9 |
0.778 |
|
| 2020 |
Rahman MT, Decker AM, Langston TL, Mathews KM, Laudermilk L, Maitra R, Ma W, Darcq E, Kieffer BL, Jin C. Design, Synthesis, and Structure-Activity Relationship Studies of (4-Alkoxyphenyl)glycinamides and Bioisosteric 1,3,4-Oxadiazoles as GPR88 Agonists. Journal of Medicinal Chemistry. PMID 33205975 DOI: 10.1021/acs.jmedchem.0c01581 |
0.667 |
|
| 2020 |
Dripps IJ, Bertels Z, Moye LS, Tipton AF, Siegersma K, Baca SM, Kieffer BL, Pradhan AA. Forebrain delta opioid receptors regulate the response of delta agonist in models of migraine and opioid-induced hyperalgesia. Scientific Reports. 10: 17629. PMID 33077757 DOI: 10.1038/s41598-020-74605-9 |
0.449 |
|
| 2020 |
Severino AL, Mittal N, Hakimian JK, Velarde N, Minasyan A, Albert R, Torres C, Romaneschi N, Johnston C, Tiwari S, Lee AS, Taylor AM, Gavériaux-Ruff C, Kieffer BL, Evans CJ, et al. Mu opioid receptors on distinct neuronal populations mediate different aspects of opioid reward-related behaviors. Eneuro. PMID 32859725 DOI: 10.1523/ENEURO.0146-20.2020 |
0.457 |
|
| 2020 |
Chen C, Willhouse AH, Huang P, Ko N, Wang Y, Xu B, Huang LHM, Kieffer B, Barbe MF, Liu-Chen LY. Characterization of a Knockin Mouse Line Expressing a Fusion Protein of Kappa Opioid Receptor Conjugated with tdTomato: 3-Dimensional Brain Imaging Via CLARITY. Eneuro. PMID 32561573 DOI: 10.1523/ENEURO.0028-20.2020 |
0.38 |
|
| 2020 |
Bailly J, Del Rossi N, Runtz L, Li JJ, Park D, Scherrer G, Tanti A, Birling MC, Darcq E, Kieffer BL. Targeting morphine-responsive neurons: generation of a knock-in mouse line expressing Cre recombinase from the mu opioid receptor gene locus. Eneuro. PMID 32381649 DOI: 10.1523/ENEURO.0433-19.2020 |
0.831 |
|
| 2020 |
Targowska-Duda KM, Ozawa A, Bertels Z, Cippitelli A, Marcus JL, Mielke-Maday HK, Zribi G, Rainey AN, Kieffer BL, Pradhan AA, Toll L. NOP receptor agonist attenuates nitroglycerin-induced migraine-like symptoms in mice. Neuropharmacology. 170: 108029. PMID 32278976 DOI: 10.1016/J.Neuropharm.2020.108029 |
0.527 |
|
| 2020 |
Laboute T, Gandía J, Pellissier LP, Corde Y, Rebeillard F, Gallo M, Gauthier C, Léauté A, Diaz J, Poupon A, Kieffer BL, Le Merrer J, Becker JA. The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs. Elife. 9. PMID 32003745 DOI: 10.7554/Elife.50519 |
0.529 |
|
| 2020 |
Laboute T, Gandía J, Pellissier LP, Corde Y, Rebeillard F, Gallo M, Gauthier C, Léauté A, Diaz J, Poupon A, Kieffer BL, Merrer JL, Becker JA. Author response: The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs Elife. DOI: 10.7554/Elife.50519.Sa2 |
0.477 |
|
| 2019 |
Nasseef MT, Singh JP, Ehrlich AT, McNicholas M, Park DW, Ma W, Kulkarni P, Kieffer BL, Darcq E. Oxycodone-Mediated Activation of the Mu Opioid Receptor Reduces Whole Brain Functional Connectivity in Mice. Acs Pharmacology & Translational Science. 2: 264-274. PMID 32259060 DOI: 10.1021/acsptsci.9b00021 |
0.831 |
|
| 2019 |
Kieffer BL. An Anti-Opioid System, Courtesy of a Worm Model. The New England Journal of Medicine. 381: 2067-2069. PMID 31747732 DOI: 10.1056/Nejmcibr1911069 |
0.487 |
|
| 2019 |
Martínez-Navarro M, Cabañero D, Wawrzczak-Bargiela A, Robe A, Gavériaux-Ruff C, Kieffer BL, Przewlocki R, Baños JE, Maldonado R. Mu and delta opioid receptors play opposite nociceptive and behavioural roles on nerve-injured mice. British Journal of Pharmacology. PMID 31655493 DOI: 10.1111/Bph.14911 |
0.5 |
|
| 2019 |
Otsu Y, Darcq E, Pietrajtis K, Mátyás F, Schwartz E, Bessaih T, Abi Gerges S, Rousseau CV, Grand T, Dieudonné S, Paoletti P, Acsády L, Agulhon C, Kieffer BL, Diana MA. Control of aversion by glycine-gated GluN1/GluN3A NMDA receptors in the adult medial habenula. Science (New York, N.Y.). 366: 250-254. PMID 31601771 DOI: 10.1126/Science.Aax1522 |
0.386 |
|
| 2019 |
Varga AG, Reid BT, Kieffer BL, Levitt ES. Differential impact of two critical respiratory centers in opioid-induced respiratory depression in awake mice. The Journal of Physiology. PMID 31589332 DOI: 10.1113/Jp278612 |
0.454 |
|
| 2019 |
Welsch L, Bailly J, Darcq E, Kieffer BL. The Negative Affect of Protracted Opioid Abstinence: Progress and Perspectives From Rodent Models. Biological Psychiatry. PMID 31521334 DOI: 10.1016/J.Biopsych.2019.07.027 |
0.766 |
|
| 2019 |
Boulos LJ, Ben Hamida S, Bailly J, Maitra M, Ehrlich AT, Gavériaux-Ruff C, Darcq E, Kieffer BL. Mu opioid receptors in the medial habenula contribute to naloxone aversion. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31005059 DOI: 10.1038/S41386-019-0395-7 |
0.79 |
|
| 2019 |
Ehrlich AT, Semache M, Gross F, Da Fonte DF, Runtz L, Colley C, Mezni A, Le Gouill C, Lukasheva V, Hogue M, Darcq E, Bouvier M, Kieffer BL. Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons. Iscience. 14: 47-57. PMID 30925410 DOI: 10.1016/J.Isci.2019.03.011 |
0.755 |
|
| 2019 |
Mann A, Moulédous L, Froment C, O'Neill PR, Dasgupta P, Günther T, Brunori G, Kieffer BL, Toll L, Bruchas MR, Zaveri NT, Schulz S. Agonist-selective NOP receptor phosphorylation correlates in vitro and in vivo and reveals differential post-activation signaling by chemically diverse agonists. Science Signaling. 12. PMID 30914485 DOI: 10.1126/Scisignal.Aau8072 |
0.466 |
|
| 2019 |
Boulos LJ, Nasseef MT, McNicholas M, Mechling A, Harsan LA, Darcq E, Ben Hamida S, Kieffer BL. TouchScreen-based phenotyping: altered stimulus/reward association and lower perseveration to gain a reward in mu opioid receptor knockout mice. Scientific Reports. 9: 4044. PMID 30858487 DOI: 10.1038/S41598-019-40622-6 |
0.808 |
|
| 2019 |
Ehrlich AT, Kieffer BL, Darcq E. Current strategies toward safer mu opioid receptor drugs for pain management. Expert Opinion On Therapeutic Targets. PMID 30802415 DOI: 10.1080/14728222.2019.1586882 |
0.753 |
|
| 2019 |
Borsodi A, Bruchas M, Caló G, Chavkin C, Christie MJ, Civelli O, Connor M, Cox BM, Devi LA, Evans C, Höllt V, Henderson G, Husbands S, Kelly E, Kieffer B, et al. Opioid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f50/2019.4 |
0.409 |
|
| 2018 |
Nasseef MT, Devenyi GA, Mechling AE, Harsan LA, Chakravarty MM, Kieffer BL, Darcq E. Deformation-based Morphometry MRI Reveals Brain Structural Modifications in Living Mu Opioid Receptor Knockout Mice. Frontiers in Psychiatry. 9: 643. PMID 30559685 DOI: 10.3389/Fpsyt.2018.00643 |
0.823 |
|
| 2018 |
Ehrlich AT, Maroteaux G, Robe A, Venteo L, Nasseef MT, van Kempen LC, Mechawar N, Turecki G, Darcq E, Kieffer BL. Expression map of 78 brain-expressed mouse orphan GPCRs provides a translational resource for neuropsychiatric research. Communications Biology. 1: 102. PMID 30271982 DOI: 10.1038/s42003-018-0106-7 |
0.778 |
|
| 2018 |
Jin C, Decker AM, Makhijani VH, Besheer J, Darcq E, Kieffer BL, Maitra R. Discovery of a Potent, Selective, and Brain-Penetrant Small-Molecule that Activates the Orphan Receptor GPR88 and Reduces Alcohol Intake. Journal of Medicinal Chemistry. PMID 30011199 DOI: 10.1021/Acs.Jmedchem.8B00566 |
0.695 |
|
| 2018 |
Darcq E, Kieffer BL. Opioid receptors: drivers to addiction? Nature Reviews. Neuroscience. PMID 29934561 DOI: 10.1038/S41583-018-0028-X |
0.765 |
|
| 2018 |
Darcq E, Kieffer BL. The Control of Reward Seeking. Biological Psychiatry. 83: 981-983. PMID 29804588 DOI: 10.1016/J.Biopsych.2018.04.003 |
0.62 |
|
| 2018 |
Schmeichel BE, Matzeu A, Koebel P, Vendruscolo LF, Sidhu H, Shahryari R, Kieffer BL, Koob GF, Martin-Fardon R, Contet C. Knockdown of hypocretin attenuates extended access of cocaine self-administration in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29703996 DOI: 10.1038/S41386-018-0054-4 |
0.78 |
|
| 2018 |
Severino A, Chen W, Hakimian JK, Kieffer BL, Gaveriaux-Ruff C, Walwyn W, Marvizon JC. Mu-opioid receptors in nociceptive afferents produce a sustained suppression of hyperalgesia in chronic pain. Pain. PMID 29677019 DOI: 10.1097/J.Pain.0000000000001247 |
0.488 |
|
| 2018 |
Ozawa A, Brunori G, Cippitelli A, Toll N, Schoch J, Kieffer BL, Toll L. Dissecting the spinal NOP receptor distribution under a chronic pain model using NOP-eGFP knock-in mice. British Journal of Pharmacology. PMID 29582417 DOI: 10.1111/Bph.14225 |
0.448 |
|
| 2018 |
Ben Hamida S, Mendonça-Netto S, Arefin TM, Nasseef MT, Boulos LJ, McNicholas M, Ehrlich AT, Clarke E, Moquin L, Gratton A, Darcq E, Harsan LA, Maldonado R, Kieffer BL. Increased Alcohol Seeking in Mice Lacking Gpr88 Involves Dysfunctional Mesocorticolimbic Networks. Biological Psychiatry. PMID 29580570 DOI: 10.1016/J.Biopsych.2018.01.026 |
0.79 |
|
| 2018 |
Maroteaux G, Arefin TM, Harsan LA, Darcq E, Ben Hamida S, Kieffer BL. Lack of anticipatory behavior in Gpr88 knockout mice showed by automatized home cage phenotyping. Genes, Brain, and Behavior. e12473. PMID 29575471 DOI: 10.1111/Gbb.12473 |
0.668 |
|
| 2018 |
Belzeaux R, Lalanne L, Kieffer BL, Lutz PE. Focusing on the Opioid System for Addiction Biomarker Discovery. Trends in Molecular Medicine. PMID 29396147 DOI: 10.1016/J.Molmed.2017.12.004 |
0.67 |
|
| 2017 |
Cruceanu C, Schmouth JF, Torres-Platas SG, Lopez JP, Ambalavanan A, Darcq E, Gross F, Breton B, Spiegelman D, Rochefort D, Hince P, Petite JM, Gauthier J, Lafrenière RG, Dion PA, ... ... Kieffer BL, et al. Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors. Molecular Psychiatry. PMID 29158579 DOI: 10.1038/mp.2017.223 |
0.678 |
|
| 2017 |
Ehrlich AT, Semache M, Bailly J, Wojcik S, Arefin TM, Colley C, Le Gouill C, Gross F, Lukasheva V, Hogue M, Darcq E, Harsan LA, Bouvier M, Kieffer BL. Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing. Brain Structure & Function. PMID 29110094 DOI: 10.1007/S00429-017-1547-3 |
0.712 |
|
| 2017 |
Ben Hamida S, Boulos LJ, McNicholas M, Charbogne P, Kieffer BL. Mu opioid receptors in GABAergic neurons of the forebrain promote alcohol reward and drinking. Addiction Biology. 24: 28-39. PMID 29094432 DOI: 10.1111/Adb.12576 |
0.744 |
|
| 2017 |
Arefin T, Mechling AE, Meirsman CA, Bienert T, Huebner NS, Lee HL, Ben Hamida S, Ehrlich A, Roquet D, Hennig J, von Elverfeldt D, Kieffer BL, Harsan LA. Remodeling of Sensorimotor Brain Connectivity in Gpr88 deficient mice. Brain Connectivity. PMID 28882062 DOI: 10.1089/Brain.2017.0486 |
0.423 |
|
| 2017 |
Meirsman AC, d'Exaerde AdK, Kieffer BL, Ouagazzal A-. GPR88 in A2A receptor-expressing neurons modulates locomotor response to dopamine agonists but not sensorimotor gating. European Journal of Neuroscience. 46: 2026-2034. PMID 28700108 DOI: 10.1111/Ejn.13646 |
0.439 |
|
| 2017 |
Abraham AD, Fontaine HM, Song AJ, Andrews MM, Baird MA, Kieffer BL, Land BB, Chavkin C. Kappa Opioid Receptor Activation in Dopamine Neurons Disrupts Behavioral Inhibition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28649993 DOI: 10.1038/Npp.2017.133 |
0.461 |
|
| 2017 |
Yoo JH, Borsodi A, Tóth G, Benyhe S, Gaspar R, Matifas A, Kieffer BL, Metaxas A, Kitchen I, Bailey A. Characterization of [(3)H] oxymorphone binding sites in mouse brain: quantitative autoradiography in opioid receptor knockout mice. Neuroscience Letters. PMID 28192197 DOI: 10.1016/J.Neulet.2017.02.002 |
0.466 |
|
| 2017 |
Boulos LJ, Darcq E, Kieffer BL. Translating the Habenula-From Rodents to Humans. Biological Psychiatry. 81: 296-305. PMID 27527822 DOI: 10.1016/J.Biopsych.2016.06.003 |
0.674 |
|
| 2016 |
Charbogne P, Gardon O, Martín-García E, Keyworth HL, Matsui A, Mechling AE, Bienert T, Nasseef T, Robé A, Moquin L, Darcq E, Ben Hamida S, Robledo P, Matifas A, Befort K, ... ... Kieffer BL, et al. Mu Opioid Receptors in Gamma-Aminobutyric Acidergic Forebrain Neurons Moderate Motivation for Heroin and Palatable Food. Biological Psychiatry. PMID 28185645 DOI: 10.1016/J.Biopsych.2016.12.022 |
0.762 |
|
| 2016 |
Manduca A, Lassalle O, Sepers M, Campolongo P, Cuomo V, Marsicano G, Kieffer B, Vanderschuren LJ, Trezza V, Manzoni OJ. Interacting Cannabinoid and Opioid Receptors in the Nucleus Accumbens Core Control Adolescent Social Play. Frontiers in Behavioral Neuroscience. 10: 211. PMID 27899885 DOI: 10.3389/Fnbeh.2016.00211 |
0.464 |
|
| 2016 |
Moore K, Madularu D, Iriah S, Yee JR, Kulkarni P, Darcq E, Kieffer BL, Ferris CF. BOLD Imaging in Awake Wild-Type and Mu-Opioid Receptor Knock-Out Mice Reveals On-Target Activation Maps in Response to Oxycodone. Frontiers in Neuroscience. 10: 471. PMID 27857679 DOI: 10.3389/Fnins.2016.00471 |
0.765 |
|
| 2016 |
Mechling AE, Arefin T, Lee HL, Bienert T, Reisert M, Ben Hamida S, Darcq E, Ehrlich A, Gaveriaux-Ruff C, Parent MJ, Rosa-Neto P, Hennig J, von Elverfeldt D, Kieffer BL, Harsan LA. Deletion of the mu opioid receptor gene in mice reshapes the reward-aversion connectome. Proceedings of the National Academy of Sciences of the United States of America. PMID 27671662 DOI: 10.1073/Pnas.1601640113 |
0.757 |
|
| 2016 |
Meirsman AC, Robé A, de Kerchove d'Exaerde A, Kieffer BL. GPR88 in A2AR Neurons Enhances Anxiety-Like Behaviors. Eneuro. 3. PMID 27570825 DOI: 10.1523/ENEURO.0202-16.2016 |
0.32 |
|
| 2016 |
Kieffer BL. Drug discovery: Designing the ideal opioid. Nature. PMID 27533037 DOI: 10.1038/Nature19424 |
0.527 |
|
| 2016 |
Celik MÖ, Labuz D, Henning K, Busch-Dienstfertig M, Gaveriaux-Ruff C, Kieffer BL, Zimmer A, Machelska H. Leukocyte opioid receptors mediate analgesia via Ca(2+)-regulated release of opioid peptides. Brain, Behavior, and Immunity. PMID 27139929 DOI: 10.1016/J.Bbi.2016.04.018 |
0.518 |
|
| 2016 |
Becker JA, Kieffer BL, Le Merrer J. Differential behavioral and molecular alterations upon protracted abstinence from cocaine versus morphine, nicotine, THC and alcohol. Addiction Biology. PMID 27126842 DOI: 10.1111/Adb.12405 |
0.379 |
|
| 2016 |
Mambretti EM, Kistner K, Mayer S, Massotte D, Kieffer BL, Hoffmann C, Reeh PW, Brack A, Asan E, Rittner HL. Functional and structural characterization of axonal opioid receptors as targets for analgesia. Molecular Pain. 12. PMID 27030709 DOI: 10.1177/1744806916628734 |
0.449 |
|
| 2016 |
Pradhan AA, Perroy J, Walwyn WM, Smith ML, Vicente-Sanchez A, Segura L, Bana A, Kieffer BL, Evans CJ. Agonist-Specific Recruitment of Arrestin Isoforms Differentially Modify Delta Opioid Receptor Function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3541-51. PMID 27013682 DOI: 10.1523/Jneurosci.4124-15.2016 |
0.533 |
|
| 2016 |
Lalanne L, Ayranci G, Filliol D, Gavériaux-Ruff C, Befort K, Kieffer BL, Lutz PE. Kappa opioid receptor antagonism and chronic antidepressant treatment have beneficial activities on social interactions and grooming deficits during heroin abstinence. Addiction Biology. PMID 27001273 DOI: 10.1111/adb.12392 |
0.63 |
|
| 2016 |
Massart R, Mignon V, Stanic J, Munoz-Tello P, Becker JA, Kieffer BL, Darmon M, Sokoloff P, Diaz J. Developmental and adult expression patterns of the G protein-coupled receptor GPR88 in the rat: Establishment of a dual nuclear-cytoplasmic localization. The Journal of Comparative Neurology. PMID 26918661 DOI: 10.1002/Cne.23991 |
0.338 |
|
| 2016 |
Zanos P, Georgiou P, Rojo Gonzalez L, Hourani S, Chen Y, Kitchen I, Kieffer BL, Winsky-Sommerer R, Bailey A. Emotional impairment and persistent up-regulation of mGlu5 receptor following morphine abstinence: implications of an mGlu5-MOPr interaction. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26861145 DOI: 10.1093/Ijnp/Pyw011 |
0.489 |
|
| 2015 |
Lalanne L, Lutz PE, Trojak B, Lang JP, Kieffer BL, Bacon E. Medications between psychiatric and addictive disorders. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 65: 215-223. PMID 26514592 DOI: 10.1016/J.Pnpbp.2015.10.009 |
0.518 |
|
| 2015 |
Erbs E, Faget L, Ceredig RA, Matifas A, Vonesch JL, Kieffer BL, Massotte D. Impact of chronic morphine on delta opioid receptor expressing neurons in the mouse hippocampus. Neuroscience. PMID 26480813 DOI: 10.1016/J.Neuroscience.2015.10.022 |
0.517 |
|
| 2015 |
Georgiou P, Zanos P, Garcia-Carmona JA, Hourani S, Kitchen I, Kieffer BL, Laorden ML, Bailey A. The oxytocin analogue carbetocin prevents priming-induced reinstatement of morphine-seeking: Involvement of dopaminergic, noradrenergic and MOPr systems. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26475574 DOI: 10.1016/J.Euroneuro.2015.09.015 |
0.516 |
|
| 2015 |
Ehrich JM, Messinger DI, Knakal CR, Kuhar JR, Schattauer SS, Bruchas MR, Zweifel LS, Kieffer BL, Phillips PE, Chavkin C. Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12917-31. PMID 26377476 DOI: 10.1523/Jneurosci.2444-15.2015 |
0.455 |
|
| 2015 |
Park MK, Kieffer B, Roberts AJ, Siggins GR, Moore SD. Interaction of CRF and Kappa Opioid Systems on GABAergic Neurotransmission in the Mouse Central Amygdala. The Journal of Pharmacology and Experimental Therapeutics. PMID 26350161 DOI: 10.1124/Jpet.115.225870 |
0.454 |
|
| 2015 |
Ozawa A, Brunori G, Mercatelli D, Wu J, Cippitelli A, Zou B, Xie XS, Williams M, Zaveri NT, Low S, Scherrer G, Kieffer BL, Toll L. Knock-In Mice with NOP-eGFP Receptors Identify Receptor Cellular and Regional Localization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11682-93. PMID 26290245 DOI: 10.1523/Jneurosci.5122-14.2015 |
0.842 |
|
| 2015 |
Meirsman AC, Le Merrer J, Pellissier LP, Diaz J, Clesse D, Kieffer BL, Becker JA. Mice Lacking GPR88 Show Motor Deficit, Improved Spatial Learning, and Low Anxiety Reversed by Delta Opioid Antagonist. Biological Psychiatry. PMID 26188600 DOI: 10.1016/J.Biopsych.2015.05.020 |
0.502 |
|
| 2015 |
Darcq E, Kieffer BL. PI3K signaling in the locus coeruleus: a new molecular pathway for ADHD research. Embo Molecular Medicine. 7: 859-61. PMID 25925427 DOI: 10.15252/Emmm.201505266 |
0.648 |
|
| 2015 |
Ayranci G, Befort K, Lalanne L, Kieffer BL, Lutz PE. Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains. Psychopharmacology. 232: 1957-71. PMID 25482274 DOI: 10.1007/S00213-014-3826-5 |
0.587 |
|
| 2015 |
Chung PC, Boehrer A, Stephan A, Matifas A, Scherrer G, Darcq E, Befort K, Kieffer BL. Delta opioid receptors expressed in forebrain GABAergic neurons are responsible for SNC80-induced seizures. Behavioural Brain Research. 278: 429-34. PMID 25447299 DOI: 10.1016/J.Bbr.2014.10.029 |
0.798 |
|
| 2015 |
Chu Sin Chung P, Keyworth HL, Martin-Garcia E, Charbogne P, Darcq E, Bailey A, Filliol D, Matifas A, Scherrer G, Ouagazzal AM, Gaveriaux-Ruff C, Befort K, Maldonado R, Kitchen I, Kieffer BL. A novel anxiogenic role for the delta opioid receptor expressed in GABAergic forebrain neurons. Biological Psychiatry. 77: 404-15. PMID 25444168 DOI: 10.1016/J.Biopsych.2014.07.033 |
0.828 |
|
| 2015 |
Megat S, Bohren Y, Doridot S, Gaveriaux-Ruff C, Kieffer BL, Freund-Mercier MJ, Yalcin I, Barrot M. κ-Opioid receptors are not necessary for the antidepressant treatment of neuropathic pain. British Journal of Pharmacology. 172: 1034-44. PMID 25297905 DOI: 10.1111/Bph.12963 |
0.52 |
|
| 2015 |
Erbs E, Faget L, Scherrer G, Matifas A, Filliol D, Vonesch JL, Koch M, Kessler P, Hentsch D, Birling MC, Koutsourakis M, Vasseur L, Veinante P, Kieffer BL, Massotte D. A mu-delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks. Brain Structure & Function. 220: 677-702. PMID 24623156 DOI: 10.1007/S00429-014-0717-9 |
0.765 |
|
| 2015 |
Darcq E, Kieffer BL. PI3K signaling in the locus coeruleus: A new molecular pathway for ADHD research Embo Molecular Medicine. 7: 859-861. DOI: 10.15252/emmm.201505266 |
0.569 |
|
| 2014 |
Bardoni R, Tawfik VL, Wang D, François A, Solorzano C, Shuster SA, Choudhury P, Betelli C, Cassidy C, Smith K, de Nooij JC, Mennicken F, O'Donnell D, Kieffer BL, Woodbury CJ, et al. Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn. Neuron. 81: 1443. PMID 28898633 DOI: 10.1016/j.neuron.2014.03.006 |
0.806 |
|
| 2014 |
Erbs E, Faget L, Veinante P, Kieffer BL, Massotte D. In vivo neuronal co-expression of mu and delta opioid receptors uncovers new therapeutic perspectives. Receptors & Clinical Investigation. 1. PMID 25938125 DOI: 10.14800/Rci.210 |
0.539 |
|
| 2014 |
Lalanne L, Ayranci G, Kieffer BL, Lutz PE. The kappa opioid receptor: from addiction to depression, and back. Frontiers in Psychiatry. 5: 170. PMID 25538632 DOI: 10.3389/Fpsyt.2014.00170 |
0.658 |
|
| 2014 |
Grieder TE, Herman MA, Contet C, Tan LA, Vargas-Perez H, Cohen A, Chwalek M, Maal-Bared G, Freiling J, Schlosburg JE, Clarke L, Crawford E, Koebel P, Repunte-Canonigo V, Sanna PP, ... ... Kieffer BL, et al. VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation. Nature Neuroscience. 17: 1751-8. PMID 25402857 DOI: 10.1038/Nn.3872 |
0.728 |
|
| 2014 |
Gardon O, Faget L, Chu Sin Chung P, Matifas A, Massotte D, Kieffer BL. Expression of mu opioid receptor in dorsal diencephalic conduction system: new insights for the medial habenula. Neuroscience. 277: 595-609. PMID 25086313 DOI: 10.1016/J.Neuroscience.2014.07.053 |
0.48 |
|
| 2014 |
Nozaki C, Nagase H, Nemoto T, Matifas A, Kieffer BL, Gaveriaux-Ruff C. In vivo properties of KNT-127, a novel δ opioid receptor agonist: receptor internalization, antihyperalgesia and antidepressant effects in mice. British Journal of Pharmacology. 171: 5376-86. PMID 25048778 DOI: 10.1111/Bph.12852 |
0.508 |
|
| 2014 |
Lutz PE, Ayranci G, Chu-Sin-Chung P, Matifas A, Koebel P, Filliol D, Befort K, Ouagazzal AM, Kieffer BL. Distinct mu, delta, and kappa opioid receptor mechanisms underlie low sociability and depressive-like behaviors during heroin abstinence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2694-705. PMID 24874714 DOI: 10.1038/Npp.2014.126 |
0.696 |
|
| 2014 |
Cohen A, Whitfield TW, Kreifeldt M, Koebel P, Kieffer BL, Contet C, George O, Koob GF. Virus-mediated shRNA knockdown of prodynorphin in the rat nucleus accumbens attenuates depression-like behavior and cocaine locomotor sensitization. Plos One. 9: e97216. PMID 24816773 DOI: 10.1371/Journal.Pone.0097216 |
0.71 |
|
| 2014 |
Yoo JH, Bailey A, Borsodi A, Tóth G, Matifas A, Kieffer BL, Kitchen I. Knockout subtraction autoradiography: a novel ex vivo method to detect heteromers finds sparse KOP receptor/DOP receptor heterodimerization in the brain. European Journal of Pharmacology. 731: 1-7. PMID 24657279 DOI: 10.1016/J.Ejphar.2014.03.007 |
0.479 |
|
| 2014 |
Becker JA, Clesse D, Spiegelhalter C, Schwab Y, Le Merrer J, Kieffer BL. Autistic-like syndrome in mu opioid receptor null mice is relieved by facilitated mGluR4 activity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2049-60. PMID 24619243 DOI: 10.1038/Npp.2014.59 |
0.499 |
|
| 2014 |
Bardoni R, Tawfik VL, Wang D, François A, Solorzano C, Shuster SA, Choudhury P, Betelli C, Cassidy C, Smith K, de Nooij JC, Mennicken F, O'Donnell D, Kieffer BL, Woodbury CJ, et al. Delta opioid receptors presynaptically regulate cutaneous mechanosensory neuron input to the spinal cord dorsal horn. Neuron. 81: 1312-27. PMID 24583022 DOI: 10.1016/J.Neuron.2014.01.044 |
0.83 |
|
| 2014 |
Cui Y, Ostlund SB, James AS, Park CS, Ge W, Roberts KW, Mittal N, Murphy NP, Cepeda C, Kieffer BL, Levine MS, Jentsch JD, Walwyn WM, Sun YE, Evans CJ, et al. Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward. Nature Neuroscience. 17: 254-61. PMID 24413699 DOI: 10.1038/Nn.3622 |
0.524 |
|
| 2014 |
Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 76: 204-17. PMID 24035914 DOI: 10.1016/J.Neuropharm.2013.08.028 |
0.547 |
|
| 2014 |
Contet C, Kim A, Le D, Iyengar SK, Kotzebue RW, Yuan CJ, Kieffer BL, Mandyam CD. μ-Opioid receptors mediate the effects of chronic ethanol binge drinking on the hippocampal neurogenic niche. Addiction Biology. 19: 770-80. PMID 23461397 DOI: 10.1111/Adb.12040 |
0.709 |
|
| 2014 |
Bardoni R, Tawfik VL, Wang D, François A, Solorzano C, Shuster SA, Choudhury P, Betelli C, Cassidy C, Smith K, deNooij JC, Mennicken F, O'Donnell D, Kieffer BL, Woodbury CJ, et al. Delta opioid receptors presynaptically regulate cutaneous mechanosensory neuron input to the spinal cord dorsal horn Neuron. 81: 1443. DOI: 10.1016/j.neuron.2014.03.006 |
0.812 |
|
| 2013 |
Rezai X, Kieffer BL, Roux MJ, Massotte D. Delta opioid receptors regulate temporoammonic-activated feedforward inhibition to the mouse CA1 hippocampus. Plos One. 8: e79081. PMID 24260157 DOI: 10.1371/Journal.Pone.0079081 |
0.527 |
|
| 2013 |
Weibel R, Reiss D, Karchewski L, Gardon O, Matifas A, Filliol D, Becker JA, Wood JN, Kieffer BL, Gaveriaux-Ruff C. Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice. Plos One. 8: e74706. PMID 24069332 DOI: 10.1371/Journal.Pone.0074706 |
0.555 |
|
| 2013 |
Chu Sin Chung P, Kieffer BL. Delta opioid receptors in brain function and diseases. Pharmacology & Therapeutics. 140: 112-20. PMID 23764370 DOI: 10.1016/J.Pharmthera.2013.06.003 |
0.553 |
|
| 2013 |
Erbs E, Pradhan AA, Matifas A, Kieffer BL, Massotte D. Evaluation of cre recombinase delivery in mammalian cells using baculovirus infection. Journal of Biotechnology. 166: 182-6. PMID 23732834 DOI: 10.1016/J.Jbiotec.2013.05.011 |
0.306 |
|
| 2013 |
Kang-Park M, Kieffer BL, Roberts AJ, Siggins GR, Moore SD. κ-Opioid receptors in the central amygdala regulate ethanol actions at presynaptic GABAergic sites. The Journal of Pharmacology and Experimental Therapeutics. 346: 130-7. PMID 23587526 DOI: 10.1124/Jpet.112.202903 |
0.392 |
|
| 2013 |
Lutz PE, Kieffer BL. The multiple facets of opioid receptor function: implications for addiction. Current Opinion in Neurobiology. 23: 473-9. PMID 23453713 DOI: 10.1016/J.Conb.2013.02.005 |
0.708 |
|
| 2013 |
Le Merrer J, Rezai X, Scherrer G, Becker JA, Kieffer BL. Impaired hippocampus-dependent and facilitated striatum-dependent behaviors in mice lacking the δ opioid receptor. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1050-9. PMID 23303070 DOI: 10.1038/Npp.2013.1 |
0.741 |
|
| 2013 |
Lutz PE, Reiss D, Ouagazzal AM, Kieffer BL. A history of chronic morphine exposure during adolescence increases despair-like behaviour and strain-dependently promotes sociability in abstinent adult mice. Behavioural Brain Research. 243: 44-52. PMID 23295400 DOI: 10.1016/J.Bbr.2012.12.049 |
0.623 |
|
| 2013 |
Lutz PE, Kieffer BL. Opioid receptors: distinct roles in mood disorders. Trends in Neurosciences. 36: 195-206. PMID 23219016 DOI: 10.1016/J.Tins.2012.11.002 |
0.69 |
|
| 2013 |
Charbogne P, Gardon O, Kitchen I, Bailey A, Matifas A, Befort K, Kieffer BL. G.12 - CONTRIBUTION OF MU OPIOID RECEPTOR EXPRESSED IN GABAERGIC FOREBRAIN NEURONS TO ADDICTION Behavioural Pharmacology. 24: e59-e60. DOI: 10.1097/01.Fbp.0000435055.98980.De |
0.504 |
|
| 2013 |
Becker JA, Le Merrer J, Kieffer BL. S.6.4 - MU OPIOID RECEPTOR MODULATION OF STRIATAL GABAERGIC SYSTEM Behavioural Pharmacology. 24: e7. DOI: 10.1097/01.Fbp.0000434707.22131.94 |
0.498 |
|
| 2012 |
Baldock PA, Driessler F, Lin S, Wong IP, Shi Y, Yulyaningsih E, Castillo L, Janmaat S, Enriquez RF, Zengin A, Kieffer BL, Schwarzer C, Eisman JA, Sainsbury A, Herzog H. The endogenous opioid dynorphin is required for normal bone homeostasis in mice. Neuropeptides. 46: 383-94. PMID 23062312 DOI: 10.1016/J.Npep.2012.08.010 |
0.448 |
|
| 2012 |
Reiss D, Prinssen EP, Wichmann J, Kieffer BL, Ouagazzal AM. The nociceptin orphanin FQ peptide receptor agonist, Ro64-6198, impairs recognition memory formation through interaction with glutamatergic but not cholinergic receptor antagonists. Neurobiology of Learning and Memory. 98: 254-60. PMID 22982481 DOI: 10.1016/J.Nlm.2012.09.002 |
0.353 |
|
| 2012 |
Erbs E, Faget L, Scherrer G, Kessler P, Hentsch D, Vonesch JL, Matifas A, Kieffer BL, Massotte D. Distribution of delta opioid receptor-expressing neurons in the mouse hippocampus. Neuroscience. 221: 203-13. PMID 22750239 DOI: 10.1016/J.Neuroscience.2012.06.023 |
0.746 |
|
| 2012 |
Pradhan AA, Smith ML, Kieffer BL, Evans CJ. Ligand-directed signalling within the opioid receptor family. British Journal of Pharmacology. 167: 960-9. PMID 22708627 DOI: 10.1111/J.1476-5381.2012.02075.X |
0.405 |
|
| 2012 |
Nozaki C, Le Bourdonnec B, Reiss D, Windh RT, Little PJ, Dolle RE, Kieffer BL, Gavériaux-Ruff C. δ-Opioid mechanisms for ADL5747 and ADL5859 effects in mice: analgesia, locomotion, and receptor internalization. The Journal of Pharmacology and Experimental Therapeutics. 342: 799-807. PMID 22700431 DOI: 10.1124/Jpet.111.188987 |
0.544 |
|
| 2012 |
Berrendero F, Plaza-Zabala A, Galeote L, Flores Ã, Bura SA, Kieffer BL, Maldonado R. Influence of δ-opioid receptors in the behavioral effects of nicotine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2332-44. PMID 22669166 DOI: 10.1038/Npp.2012.88 |
0.513 |
|
| 2012 |
Faget L, Erbs E, Le Merrer J, Scherrer G, Matifas A, Benturquia N, Noble F, Decossas M, Koch M, Kessler P, Vonesch JL, Schwab Y, Kieffer BL, Massotte D. In vivo visualization of delta opioid receptors upon physiological activation uncovers a distinct internalization profile. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7301-10. PMID 22623675 DOI: 10.1523/Jneurosci.0185-12.2012 |
0.753 |
|
| 2012 |
Del Boca C, Lutz PE, Le Merrer J, Koebel P, Kieffer BL. Cholecystokinin knock-down in the basolateral amygdala has anxiolytic and antidepressant-like effects in mice. Neuroscience. 218: 185-95. PMID 22613736 DOI: 10.1016/J.Neuroscience.2012.05.022 |
0.593 |
|
| 2012 |
Nguyen AT, Marquez P, Hamid A, Kieffer B, Friedman TC, Lutfy K. The rewarding action of acute cocaine is reduced in β-endorphin deficient but not in μ opioid receptor knockout mice. European Journal of Pharmacology. 686: 50-4. PMID 22575525 DOI: 10.1016/J.Ejphar.2012.04.040 |
0.452 |
|
| 2012 |
Le Merrer J, Faget L, Matifas A, Kieffer BL. Cues predicting drug or food reward restore morphine-induced place conditioning in mice lacking delta opioid receptors. Psychopharmacology. 223: 99-106. PMID 22526530 DOI: 10.1007/S00213-012-2693-1 |
0.504 |
|
| 2012 |
Rezaï X, Faget L, Bednarek E, Schwab Y, Kieffer BL, Massotte D. Mouse δ opioid receptors are located on presynaptic afferents to hippocampal pyramidal cells. Cellular and Molecular Neurobiology. 32: 509-16. PMID 22252784 DOI: 10.1007/S10571-011-9791-1 |
0.533 |
|
| 2012 |
Darcq E, Befort K, Koebel P, Pannetier S, Mahoney MK, Gaveriaux-Ruff C, Hanauer A, Kieffer BL. RSK2 signaling in medial habenula contributes to acute morphine analgesia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1288-96. PMID 22218090 DOI: 10.1038/Npp.2011.316 |
0.753 |
|
| 2012 |
Le Merrer J, Befort K, Gardon O, Filliol D, Darcq E, Dembele D, Becker JA, Kieffer BL. Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network. Addiction Biology. 17: 1-12. PMID 21955143 DOI: 10.1111/J.1369-1600.2011.00365.X |
0.702 |
|
| 2012 |
Ces A, Reiss D, Walter O, Wichmann J, Prinssen EP, Kieffer BL, Ouagazzal AM. Activation of nociceptin/orphanin FQ peptide receptors disrupts visual but not auditory sensorimotor gating in BALB/cByJ mice: comparison to dopamine receptor agonists. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 378-89. PMID 21881568 DOI: 10.1038/Npp.2011.175 |
0.432 |
|
| 2012 |
Kieffer B. PL.06.01 Opioid systems: probing molecular processes of brain function European Neuropsychopharmacology. 22: S111-S112. DOI: 10.1016/S0924-977X(12)70114-1 |
0.309 |
|
| 2011 |
Karaji AG, Reiss D, Matifas A, Kieffer BL, Gavériaux-Ruff C. Influence of endogenous opioid systems on T lymphocytes as assessed by the knockout of mu, delta and kappa opioid receptors. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 6: 608-16. PMID 21938479 DOI: 10.1007/S11481-011-9314-3 |
0.495 |
|
| 2011 |
Pradhan AA, Befort K, Nozaki C, Gavériaux-Ruff C, Kieffer BL. The delta opioid receptor: an evolving target for the treatment of brain disorders. Trends in Pharmacological Sciences. 32: 581-90. PMID 21925742 DOI: 10.1016/J.Tips.2011.06.008 |
0.552 |
|
| 2011 |
Darcq E, Koebel P, Del Boca C, Pannetier S, Kirstetter AS, Garnier JM, Hanauer A, Befort K, Kieffer BL. RSK2 signaling in brain habenula contributes to place aversion learning. Learning & Memory (Cold Spring Harbor, N.Y.). 18: 574-8. PMID 21852432 DOI: 10.1101/Lm.2221011 |
0.647 |
|
| 2011 |
Gavériaux-Ruff C, Kieffer BL. Delta opioid receptor analgesia: recent contributions from pharmacology and molecular approaches. Behavioural Pharmacology. 22: 405-14. PMID 21836459 DOI: 10.1097/Fbp.0B013E32834A1F2C |
0.513 |
|
| 2011 |
Nozaki C, Vergnano AM, Filliol D, Ouagazzal AM, Le Goff A, Carvalho S, Reiss D, Gaveriaux-Ruff C, Neyton J, Paoletti P, Kieffer BL. Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit. Nature Neuroscience. 14: 1017-22. PMID 21725314 DOI: 10.1038/Nn.2844 |
0.378 |
|
| 2011 |
Poole DP, Pelayo JC, Scherrer G, Evans CJ, Kieffer BL, Bunnett NW. Localization and regulation of fluorescently labeled delta opioid receptor, expressed in enteric neurons of mice. Gastroenterology. 141: 982-991.e1-8. PMID 21699782 DOI: 10.1053/J.Gastro.2011.05.042 |
0.734 |
|
| 2011 |
Lutz PE, Pradhan AA, Goeldner C, Kieffer BL. Sequential and opposing alterations of 5-HT(1A) receptor function during withdrawal from chronic morphine. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 21: 835-40. PMID 21402471 DOI: 10.1016/J.Euroneuro.2011.02.002 |
0.613 |
|
| 2011 |
Contet C, Gardon O, Filliol D, Becker JA, Koob GF, Kieffer BL. Identification of genes regulated in the mouse extended amygdala by excessive ethanol drinking associated with dependence. Addiction Biology. 16: 615-9. PMID 21392173 DOI: 10.1111/J.1369-1600.2010.00304.X |
0.729 |
|
| 2011 |
Gaveriaux-Ruff C, Nozaki C, Nadal X, Hever XC, Weibel R, Matifas A, Reiss D, Filliol D, Nassar MA, Wood JN, Maldonado R, Kieffer BL. Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia. Pain. 152: 1238-48. PMID 21295407 DOI: 10.1016/J.Pain.2010.12.031 |
0.505 |
|
| 2011 |
Befort K, Mahoney MK, Chow C, Hayton SJ, Kieffer BL, Olmstead MC. Effects of delta opioid receptors activation on a response inhibition task in rats. Psychopharmacology. 214: 967-76. PMID 21181131 DOI: 10.1007/S00213-010-2108-0 |
0.499 |
|
| 2011 |
Le Merrer J, Plaza-Zabala A, Del Boca C, Matifas A, Maldonado R, Kieffer BL. Deletion of the δ opioid receptor gene impairs place conditioning but preserves morphine reinforcement. Biological Psychiatry. 69: 700-3. PMID 21168121 DOI: 10.1016/J.Biopsych.2010.10.021 |
0.515 |
|
| 2011 |
Goeldner C, Lutz PE, Darcq E, Halter T, Clesse D, Ouagazzal AM, Kieffer BL. Impaired emotional-like behavior and serotonergic function during protracted abstinence from chronic morphine. Biological Psychiatry. 69: 236-44. PMID 20947067 DOI: 10.1016/J.Biopsych.2010.08.021 |
0.775 |
|
| 2011 |
Weibel R, Gaveriaux-Ruff C, Nozaki C, Nadal X, Hever XC, Matifas A, Reiss D, Filliol D, Wood JN, Maldonado R, Kieffer BL. Genetic ablation of δ opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes analgesia Pharmacological Reports. 63: 243-243. DOI: 10.1016/S1734-1140(11)70465-0 |
0.474 |
|
| 2011 |
Kieffer B, Befort K, Goeldner C, Becker J, Merrer JL. S.15.03 From the gene to behaviour to more genes: the mu-opioid receptor as an example in addiction research European Neuropsychopharmacology. 21. DOI: 10.1016/S0924-977X(11)70299-1 |
0.438 |
|
| 2011 |
Scherrer G, Kieffer BL. A new approach to visualize endogenously expressed G protein-coupled receptors in tissues and living cells Neuromethods. 60: 105-131. DOI: 10.1007/978-1-61779-179-6_6 |
0.607 |
|
| 2010 |
Pradhan AA, Walwyn W, Nozaki C, Filliol D, Erbs E, Matifas A, Evans C, Kieffer BL. Ligand-directed trafficking of the δ-opioid receptor in vivo: two paths toward analgesic tolerance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16459-68. PMID 21147985 DOI: 10.1523/Jneurosci.3748-10.2010 |
0.528 |
|
| 2010 |
Yoo JH, Bailey A, Ansonoff M, Pintar JE, Matifas A, Kieffer BL, Kitchen I. Lack of genotype effect on D1, D2 receptors and dopamine transporter binding in triple MOP-, DOP-, and KOP-opioid receptor knockout mice of three different genetic backgrounds. Synapse (New York, N.Y.). 64: 520-7. PMID 20196137 DOI: 10.1002/Syn.20757 |
0.416 |
|
| 2010 |
Goeldner C, Reiss D, Kieffer BL, Ouagazzal AM. Endogenous nociceptin/orphanin-FQ in the dorsal hippocampus facilitates despair-related behavior. Hippocampus. 20: 911-6. PMID 20087887 DOI: 10.1002/Hipo.20760 |
0.4 |
|
| 2010 |
Bohren Y, Karavelic D, Tessier LH, Yalcin I, Gavériaux-Ruff C, Kieffer BL, Freund-Mercier MJ, Barrot M. Mu-opioid receptors are not necessary for nortriptyline treatment of neuropathic allodynia. European Journal of Pain (London, England). 14: 700-4. PMID 20056557 DOI: 10.1016/J.Ejpain.2009.11.014 |
0.491 |
|
| 2010 |
Poole DP, Pelayo JC, Scherrer G, Basbaum AI, Kieffer BL, Bunnett NW. 966 Localization and Function of Fluorescently-Tagged Delta Opioid Receptor (DOR) Expressed in Enteric Neurons of Knockin Mice Gastroenterology. 138: S-142. DOI: 10.1016/S0016-5085(10)60650-6 |
0.788 |
|
| 2010 |
Baldock P, Driessler F, Wong I, Kieffer B, Schwarzer C, Sainsbury A, Herzog H, Eisman J. Neuropeptide Y is Critical to the Central Effects of the Endogenous Opioid System on Bone Bone. 46: S68. DOI: 10.1016/J.Bone.2010.01.164 |
0.387 |
|
| 2010 |
Kieffer BL. Opioid Peptides and Receptors Encyclopedia of Neuroscience. 235-240. DOI: 10.1016/B978-008045046-9.01472-8 |
0.331 |
|
| 2009 |
Le Merrer J, Becker JA, Befort K, Kieffer BL. Reward processing by the opioid system in the brain. Physiological Reviews. 89: 1379-412. PMID 19789384 DOI: 10.1152/Physrev.00005.2009 |
0.538 |
|
| 2009 |
Scherrer G, Imamachi N, Cao YQ, Contet C, Mennicken F, O'Donnell D, Kieffer BL, Basbaum AI. Dissociation of the opioid receptor mechanisms that control mechanical and heat pain. Cell. 137: 1148-59. PMID 19524516 DOI: 10.1016/J.Cell.2009.04.019 |
0.817 |
|
| 2009 |
Pradhan AA, Becker JA, Scherrer G, Tryoen-Toth P, Filliol D, Matifas A, Massotte D, Gavériaux-Ruff C, Kieffer BL. In vivo delta opioid receptor internalization controls behavioral effects of agonists. Plos One. 4: e5425. PMID 19412545 DOI: 10.1371/Journal.Pone.0005425 |
0.743 |
|
| 2009 |
Kieffer B, Gavériaux-Ruff C, Befort K, Massotte D, Becker J. S.1.01 Brain opioid receptor systems: molecular and functional aspects European Neuropsychopharmacology. 19. PMID 19304142 DOI: 10.1016/S0924-977X(09)70002-1 |
0.487 |
|
| 2009 |
Olmstead MC, Ouagazzal AM, Kieffer BL. Mu and delta opioid receptors oppositely regulate motor impulsivity in the signaled nose poke task. Plos One. 4: e4410. PMID 19198656 DOI: 10.1371/Journal.Pone.0004410 |
0.52 |
|
| 2009 |
Goeldner C, Reiss D, Wichmann J, Kieffer BL, Ouagazzal AM. Activation of nociceptin opioid peptide (NOP) receptor impairs contextual fear learning in mice through glutamatergic mechanisms. Neurobiology of Learning and Memory. 91: 393-401. PMID 19100850 DOI: 10.1016/J.Nlm.2008.12.001 |
0.378 |
|
| 2009 |
Kang-Park MH, Kieffer BL, Roberts AJ, Roberto M, Madamba SG, Siggins GR, Moore SD. Mu-opioid receptors selectively regulate basal inhibitory transmission in the central amygdala: lack of ethanol interactions. The Journal of Pharmacology and Experimental Therapeutics. 328: 284-93. PMID 18854491 DOI: 10.1124/Jpet.108.140749 |
0.458 |
|
| 2009 |
Kieffer BL, Evans CJ. Opioid receptors: from binding sites to visible molecules in vivo. Neuropharmacology. 56: 205-12. PMID 18718480 DOI: 10.1016/J.Neuropharm.2008.07.033 |
0.546 |
|
| 2009 |
Pradhan A, Gardon O, Becker J, Blad C, Filliol D, Matifas A, Kieffer B. P.1.26 Conditional knockout of mu opioid receptors European Neuropsychopharmacology. 19: S23-S24. DOI: 10.1016/S0924-977X(09)70029-X |
0.327 |
|
| 2009 |
Kieffer BL. Live molecular recognition: Visualizing opioid receptors trafficking in vivo Journal of Inclusion Phenomena and Macrocyclic Chemistry. 65: 189-195. DOI: 10.1007/S10847-009-9637-3 |
0.524 |
|
| 2008 |
Becker JA, Befort K, Blad C, Filliol D, Ghate A, Dembele D, Thibault C, Koch M, Muller J, Lardenois A, Poch O, Kieffer BL. Transcriptome analysis identifies genes with enriched expression in the mouse central extended amygdala. Neuroscience. 156: 950-65. PMID 18786617 DOI: 10.1016/J.Neuroscience.2008.07.070 |
0.342 |
|
| 2008 |
Befort K, Filliol D, Darcq E, Ghate A, Matifas A, Lardenois A, Muller J, Thibault C, Dembele D, Poch O, Kieffer BL. Gene expression is altered in the lateral hypothalamus upon activation of the mu opioid receptor. Annals of the New York Academy of Sciences. 1129: 175-84. PMID 18591478 DOI: 10.1196/Annals.1417.028 |
0.772 |
|
| 2008 |
Befort K, Filliol D, Ghate A, Darcq E, Matifas A, Muller J, Lardenois A, Thibault C, Dembele D, Le Merrer J, Becker JA, Poch O, Kieffer BL. Mu-opioid receptor activation induces transcriptional plasticity in the central extended amygdala. The European Journal of Neuroscience. 27: 2973-84. PMID 18588537 DOI: 10.1111/J.1460-9568.2008.06273.X |
0.771 |
|
| 2008 |
Gavériaux-Ruff C, Karchewski LA, Hever X, Matifas A, Kieffer BL. Inflammatory pain is enhanced in delta opioid receptor-knockout mice. The European Journal of Neuroscience. 27: 2558-67. PMID 18513322 DOI: 10.1111/J.1460-9568.2008.06223.X |
0.499 |
|
| 2008 |
Goeldner C, Reiss D, Wichmann J, Meziane H, Kieffer BL, Ouagazzal AM. Nociceptin receptor impairs recognition memory via interaction with NMDA receptor-dependent mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2190-8. PMID 18305252 DOI: 10.1523/Jneurosci.3711-07.2008 |
0.317 |
|
| 2008 |
Snook LA, Milligan G, Kieffer BL, Massotte D. Co-expression of mu and delta opioid receptors as receptor-G protein fusions enhances both mu and delta signalling via distinct mechanisms. Journal of Neurochemistry. 105: 865-73. PMID 18182056 DOI: 10.1111/J.1471-4159.2008.05215.X |
0.493 |
|
| 2008 |
Contet C, Filliol D, Matifas A, Kieffer BL. Morphine-induced analgesic tolerance, locomotor sensitization and physical dependence do not require modification of mu opioid receptor, cdk5 and adenylate cyclase activity. Neuropharmacology. 54: 475-86. PMID 18082850 DOI: 10.1016/J.Neuropharm.2007.10.015 |
0.785 |
|
| 2008 |
Reiss D, Wichmann J, Tekeshima H, Kieffer BL, Ouagazzal AM. Effects of nociceptin/orphanin FQ receptor (NOP) agonist, Ro64-6198, on reactivity to acute pain in mice: comparison to morphine. European Journal of Pharmacology. 579: 141-8. PMID 18031727 DOI: 10.1016/J.Ejphar.2007.10.031 |
0.485 |
|
| 2008 |
David V, Matifas A, Gavello-Baudy S, Decorte L, Kieffer BL, Cazala P. Brain regional Fos expression elicited by the activation of mu- but not delta-opioid receptors of the ventral tegmental area: evidence for an implication of the ventral thalamus in opiate reward. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1746-59. PMID 17895918 DOI: 10.1038/Sj.Npp.1301529 |
0.537 |
|
| 2008 |
Benbouzid M, Gavériaux-Ruff C, Yalcin I, Waltisperger E, Tessier LH, Muller A, Kieffer BL, Freund-Mercier MJ, Barrot M. Delta-opioid receptors are critical for tricyclic antidepressant treatment of neuropathic allodynia. Biological Psychiatry. 63: 633-6. PMID 17693391 DOI: 10.1016/J.Biopsych.2007.06.016 |
0.51 |
|
| 2007 |
Papaleo F, Kieffer BL, Tabarin A, Contarino A. Decreased motivation to eat in mu-opioid receptor-deficient mice. The European Journal of Neuroscience. 25: 3398-405. PMID 17553008 DOI: 10.1111/J.1460-9568.2007.05595.X |
0.404 |
|
| 2007 |
Ghate A, Befort K, Becker JA, Filliol D, Bole-Feysot C, Demebele D, Jost B, Koch M, Kieffer BL. Identification of novel striatal genes by expression profiling in adult mouse brain. Neuroscience. 146: 1182-92. PMID 17395390 DOI: 10.1016/J.Neuroscience.2007.02.040 |
0.326 |
|
| 2007 |
Marquez P, Baliram R, Kieffer BL, Lutfy K. The mu opioid receptor is involved in buprenorphine-induced locomotor stimulation and conditioned place preference. Neuropharmacology. 52: 1336-41. PMID 17367825 DOI: 10.1016/J.Neuropharm.2007.01.005 |
0.435 |
|
| 2007 |
Chakass D, Philippe D, Erdual E, Dharancy S, Malapel M, Dubuquoy C, Thuru X, Gay J, Gaveriaux-Ruff C, Dubus P, Mathurin P, Kieffer BL, Desreumaux P, Chamaillard M. micro-Opioid receptor activation prevents acute hepatic inflammation and cell death. Gut. 56: 974-81. PMID 17299060 DOI: 10.1136/Gut.2006.105122 |
0.387 |
|
| 2007 |
Gavériaux-Ruff C, Kieffer BL. Conditional gene targeting in the mouse nervous system: Insights into brain function and diseases. Pharmacology & Therapeutics. 113: 619-34. PMID 17289150 DOI: 10.1016/J.Pharmthera.2006.12.003 |
0.371 |
|
| 2007 |
Contet C, Dierich A, Kieffer BL. Knock-in mice reveal nonsense-mediated mRNA decay in the brain. Genesis (New York, N.Y. : 2000). 45: 38-43. PMID 17216605 DOI: 10.1002/Dvg.20263 |
0.727 |
|
| 2007 |
Nagai J, Kurokawa M, Takeshima H, Kieffer BL, Ueda H. Circadian-dependent learning and memory enhancement in nociceptin receptor-deficient mice with a novel KUROBOX apparatus using stress-free positive cue task. The Journal of Pharmacology and Experimental Therapeutics. 321: 195-201. PMID 17209168 DOI: 10.1124/Jpet.106.115121 |
0.337 |
|
| 2007 |
Bigliardi-Qi M, Gaveriaux-Ruff C, Pfaltz K, Bady P, Baumann T, Rufli T, Kieffer BL, Bigliardi PL. Deletion of mu- and kappa-opioid receptors in mice changes epidermal hypertrophy, density of peripheral nerve endings, and itch behavior. The Journal of Investigative Dermatology. 127: 1479-88. PMID 17185983 DOI: 10.1038/Sj.Jid.5700661 |
0.428 |
|
| 2007 |
Kang-Park MH, Kieffer BL, Roberts AJ, Siggins GR, Moore SD. Presynaptic delta opioid receptors regulate ethanol actions in central amygdala. The Journal of Pharmacology and Experimental Therapeutics. 320: 917-25. PMID 17114568 DOI: 10.1124/Jpet.106.112722 |
0.43 |
|
| 2007 |
GarcÃa-Fuster MJ, Ferrer-Alcón M, MartÃn M, Kieffer BL, Maldonado R, GarcÃa-Sevilla JA. Effects of constitutive deletion of opioid receptors on the basal densities of Fas and Fas-associated protein with death domain (FADD) in the mouse brain: a delta-opioid tone inhibits FADD. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 17: 366-74. PMID 17030115 DOI: 10.1016/J.Euroneuro.2006.08.008 |
0.544 |
|
| 2007 |
Bigliardi-Qi M, Gaveriaux-Ruff C, Zhou H, Hell C, Bady P, Rufli T, Kieffer B, Bigliardi P. Deletion of delta-opioid receptor in mice alters skin differentiation and delays wound healing. Differentiation; Research in Biological Diversity. 74: 174-85. PMID 16683988 DOI: 10.1111/J.1432-0436.2006.00065.X |
0.384 |
|
| 2006 |
Walwyn WM, Wei W, Xie CW, Chiu K, Kieffer BL, Evans CJ, Maidment NT. Mu opioid receptor-effector coupling and trafficking in dorsal root ganglia neurons. Neuroscience. 142: 493-503. PMID 16887280 DOI: 10.1016/J.Neuroscience.2006.06.021 |
0.531 |
|
| 2006 |
Scherrer G, Tryoen-Tóth P, Filliol D, Matifas A, Laustriat D, Cao YQ, Basbaum AI, Dierich A, Vonesh JL, Gavériaux-Ruff C, Kieffer BL. Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo. Proceedings of the National Academy of Sciences of the United States of America. 103: 9691-6. PMID 16766653 DOI: 10.1073/Pnas.0603359103 |
0.784 |
|
| 2006 |
Snook LA, Milligan G, Kieffer BL, Massotte D. Mu-delta opioid receptor functional interaction: Insight using receptor-G protein fusions. The Journal of Pharmacology and Experimental Therapeutics. 318: 683-90. PMID 16690720 DOI: 10.1124/Jpet.106.101220 |
0.428 |
|
| 2006 |
Galeote L, Kieffer BL, Maldonado R, Berrendero F. Mu-opioid receptors are involved in the tolerance to nicotine antinociception. Journal of Neurochemistry. 97: 416-23. PMID 16539669 DOI: 10.1111/J.1471-4159.2006.03751.X |
0.528 |
|
| 2006 |
Merg F, Filliol D, Usynin I, Bazov I, Bark N, Hurd YL, Yakovleva T, Kieffer BL, Bakalkin G. Big dynorphin as a putative endogenous ligand for the kappa-opioid receptor. Journal of Neurochemistry. 97: 292-301. PMID 16515546 DOI: 10.1111/J.1471-4159.2006.03732.X |
0.481 |
|
| 2006 |
Nadal X, Baños JE, Kieffer BL, Maldonado R. Neuropathic pain is enhanced in delta-opioid receptor knockout mice. The European Journal of Neuroscience. 23: 830-4. PMID 16487163 DOI: 10.1111/J.1460-9568.2006.04569.X |
0.443 |
|
| 2006 |
Simonin F, Schmitt M, Laulin JP, Laboureyras E, Jhamandas JH, MacTavish D, Matifas A, Mollereau C, Laurent P, Parmentier M, Kieffer BL, Bourguignon JJ, Simonnet G. RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia. Proceedings of the National Academy of Sciences of the United States of America. 103: 466-71. PMID 16407169 DOI: 10.1073/Pnas.0502090103 |
0.499 |
|
| 2006 |
Contet C, Gavériaux-Ruff C, Matifas A, Caradec C, Champy MF, Kieffer BL. Dissociation of analgesic and hormonal responses to forced swim stress using opioid receptor knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1733-44. PMID 16237385 DOI: 10.1038/Sj.Npp.1300934 |
0.755 |
|
| 2006 |
Berrendero F, Galeote L, Bura A, Kieffer B, Maldonado R. P.6.d.022 Behavioural responses induced by nicotine in delta-opioid receptor knockout mice European Neuropsychopharmacology. 16: S518-S519. DOI: 10.1016/S0924-977X(06)70713-1 |
0.465 |
|
| 2005 |
Tabarin A, Diz-Chaves Y, Chaves YD, Carmona Mdel C, Catargi B, Zorrilla EP, Roberts AJ, Coscina DV, Rousset S, Redonnet A, Parker GC, Inoue K, Ricquier D, Pénicaud L, Kieffer BL, et al. Resistance to diet-induced obesity in mu-opioid receptor-deficient mice: evidence for a "thrifty gene". Diabetes. 54: 3510-6. PMID 16306369 DOI: 10.2337/Diabetes.54.12.3510 |
0.422 |
|
| 2005 |
Walwyn W, Maidment NT, Sanders M, Evans CJ, Kieffer BL, Hales TG. Induction of delta opioid receptor function by up-regulation of membrane receptors in mouse primary afferent neurons. Molecular Pharmacology. 68: 1688-98. PMID 16135785 DOI: 10.1124/Mol.105.014829 |
0.475 |
|
| 2005 |
Nieto MM, Guen SL, Kieffer BL, Roques BP, Noble F. Physiological control of emotion-related behaviors by endogenous enkephalins involves essentially the delta opioid receptors. Neuroscience. 135: 305-13. PMID 16112476 DOI: 10.1016/J.Neuroscience.2005.06.025 |
0.485 |
|
| 2005 |
Ghozland S, Chu K, Kieffer BL, Roberts AJ. Lack of stimulant and anxiolytic-like effects of ethanol and accelerated development of ethanol dependence in mu-opioid receptor knockout mice. Neuropharmacology. 49: 493-501. PMID 15961126 DOI: 10.1016/J.Neuropharm.2005.04.006 |
0.427 |
|
| 2005 |
Sanders MJ, Kieffer BL, Fanselow MS. Deletion of the mu opioid receptor results in impaired acquisition of Pavlovian context fear. Neurobiology of Learning and Memory. 84: 33-41. PMID 15936681 DOI: 10.1016/J.Nlm.2005.03.001 |
0.513 |
|
| 2005 |
Kovacs KM, Szakall I, O'Brien D, Wang R, Vinod KY, Saito M, Simonin F, Kieffer BL, Vadasz C. Decreased oral self-administration of alcohol in kappa-opioid receptor knock-out mice. Alcoholism, Clinical and Experimental Research. 29: 730-8. PMID 15897716 DOI: 10.1097/01.Alc.0000164361.62346.D6 |
0.402 |
|
| 2005 |
Grillet N, Pattyn A, Contet C, Kieffer BL, Goridis C, Brunet JF. Generation and characterization of Rgs4 mutant mice. Molecular and Cellular Biology. 25: 4221-8. PMID 15870291 DOI: 10.1128/Mcb.25.10.4221-4228.2005 |
0.732 |
|
| 2005 |
Massotte D, Kieffer BL. The second extracellular loop: a damper for G protein-coupled receptors? Nature Structural & Molecular Biology. 12: 287-8. PMID 15809647 DOI: 10.1038/Nsmb0405-287 |
0.353 |
|
| 2005 |
Tryoen-Tóth P, Décaillot FM, Filliol D, Befort K, Lazarus LH, Schiller PW, Schmidhammer H, Kieffer BL. Inverse agonism and neutral antagonism at wild-type and constitutively active mutant delta opioid receptors. The Journal of Pharmacology and Experimental Therapeutics. 313: 410-21. PMID 15590769 DOI: 10.1124/Jpet.104.077321 |
0.439 |
|
| 2005 |
Galeote L, Maldonado R, Kieffer B, Berrendero F. B60 INVOLVEMENT OF OPIOID RECEPTORS IN THE TOLERANCE TO NICOTINE ANTINOCICEPTIVE EFFECTS Behavioural Pharmacology. 16: S84-S85. DOI: 10.1097/00008877-200509001-00265 |
0.459 |
|
| 2005 |
Monsaingeon M, Diz-Chaves Y, Zorrilla E, Kieffer B, Corcuff J, Roberts A, Koob G, Tabarin A. CO21 - Modulation du comportement alimentaire par le système opioïde endogène mu Annales D'Endocrinologie. 66: 398. DOI: 10.1016/S0003-4266(05)81822-0 |
0.328 |
|
| 2004 |
Chefer VI, Kieffer BL, Shippenberg TS. Contrasting effects of mu opioid receptor and delta opioid receptor deletion upon the behavioral and neurochemical effects of cocaine. Neuroscience. 127: 497-503. PMID 15262338 DOI: 10.1016/J.Neuroscience.2004.05.021 |
0.434 |
|
| 2004 |
Robledo P, Mendizabal V, Ortuño J, de la Torre R, Kieffer BL, Maldonado R. The rewarding properties of MDMA are preserved in mice lacking mu-opioid receptors. The European Journal of Neuroscience. 20: 853-8. PMID 15255997 DOI: 10.1111/J.1460-9568.2004.03532.X |
0.55 |
|
| 2004 |
Moles A, Kieffer BL, D'Amato FR. Deficit in attachment behavior in mice lacking the mu-opioid receptor gene. Science (New York, N.Y.). 304: 1983-6. PMID 15218152 DOI: 10.1126/Science.1095943 |
0.516 |
|
| 2004 |
Contet C, Kieffer BL, Befort K. Mu opioid receptor: a gateway to drug addiction. Current Opinion in Neurobiology. 14: 370-8. PMID 15194118 DOI: 10.1016/J.Conb.2004.05.005 |
0.792 |
|
| 2004 |
Contet C, Matifas A, Kieffer BL. No evidence for G-protein-coupled epsilon receptor in the brain of triple opioid receptor knockout mouse. European Journal of Pharmacology. 492: 131-6. PMID 15178356 DOI: 10.1016/J.Ejphar.2004.03.056 |
0.772 |
|
| 2004 |
Morinville A, Cahill CM, Kieffer B, Collier B, Beaudet A. Mu-opioid receptor knockout prevents changes in delta-opioid receptor trafficking induced by chronic inflammatory pain. Pain. 109: 266-73. PMID 15157687 DOI: 10.1016/J.Pain.2004.01.011 |
0.478 |
|
| 2004 |
Dierich A, Kieffer BL. Knockout mouse models in pain research. Methods in Molecular Medicine. 99: 269-99. PMID 15131344 DOI: 10.1385/1-59259-770-X:167 |
0.444 |
|
| 2004 |
Gouardères C, Kieffer BL, Zajac JM. Opposite alterations of NPFF1 and NPFF2 neuropeptide FF receptor density in the triple MOR/DOR/KOR-opioid receptor knockout mouse brains. Journal of Chemical Neuroanatomy. 27: 119-28. PMID 15121216 DOI: 10.1016/J.Jchemneu.2004.01.002 |
0.54 |
|
| 2004 |
Scherrer G, Befort K, Contet C, Becker J, Matifas A, Kieffer BL. The delta agonists DPDPE and deltorphin II recruit predominantly mu receptors to produce thermal analgesia: a parallel study of mu, delta and combinatorial opioid receptor knockout mice. The European Journal of Neuroscience. 19: 2239-48. PMID 15090050 DOI: 10.1111/j.0953-816X.2004.03339.x |
0.833 |
|
| 2004 |
Simonin F, Karcher P, Boeuf JJ, Matifas A, Kieffer BL. Identification of a novel family of G protein-coupled receptor associated sorting proteins. Journal of Neurochemistry. 89: 766-75. PMID 15086532 DOI: 10.1111/J.1471-4159.2004.02411.X |
0.394 |
|
| 2004 |
Léna I, Matthes H, Kieffer B, Kitchen I. Quantitative autoradiography of dopamine receptors in the brains of micro-opioid receptor knockout mice. Neuroscience Letters. 356: 220-4. PMID 15036634 DOI: 10.1016/J.Neulet.2003.11.058 |
0.401 |
|
| 2004 |
GarcÃa-Sevilla JA, Ferrer-Alcón M, MartÃn M, Kieffer BL, Maldonado R. Neurofilament proteins and cAMP pathway in brains of mu-, delta- or kappa-opioid receptor gene knock-out mice: effects of chronic morphine administration. Neuropharmacology. 46: 519-30. PMID 14975676 DOI: 10.1016/J.Neuropharm.2003.10.006 |
0.538 |
|
| 2004 |
Gaveriaux-Ruff C, Simonin F, Filliol D, Kieffer B. Antibody response and allogeneic mixed lymphocyte reaction in mu-, delta-, and kappa-opioid receptor knockout mice. Journal of Neuroimmunology. 147: 121-2. PMID 14741441 DOI: 10.1016/J.Jneuroim.2003.10.025 |
0.537 |
|
| 2004 |
Walwyn WM, Keith DE, Wei W, Tan AM, Xie CW, Evans CJ, Kieffer BL, Maidment NT. Functional coupling, desensitization and internalization of virally expressed mu opioid receptors in cultured dorsal root ganglion neurons from mu opioid receptor knockout mice. Neuroscience. 123: 111-21. PMID 14667446 DOI: 10.1016/J.Neuroscience.2003.08.060 |
0.433 |
|
| 2004 |
Wang D, Raehal KM, Lin ET, Lowery JJ, Kieffer BL, Bilsky EJ, Sadée W. Basal signaling activity of mu opioid receptor in mouse brain: role in narcotic dependence. The Journal of Pharmacology and Experimental Therapeutics. 308: 512-20. PMID 14600246 DOI: 10.1124/Jpet.103.054049 |
0.518 |
|
| 2003 |
Brillet K, Kieffer BL, Massotte D. Enhanced spontaneous activity of the mu opioid receptor by cysteine mutations: characterization of a tool for inverse agonist screening. Bmc Pharmacology. 3: 14. PMID 14641935 DOI: 10.1186/1471-2210-3-14 |
0.482 |
|
| 2003 |
Romberg R, Sarton E, Teppema L, Matthes HW, Kieffer BL, Dahan A. Comparison of morphine-6-glucuronide and morphine on respiratory depressant and antinociceptive responses in wild type and mu-opioid receptor deficient mice. British Journal of Anaesthesia. 91: 862-70. PMID 14633759 DOI: 10.1093/bja/aeg279 |
0.379 |
|
| 2003 |
Chefer VI, Kieffer BL, Shippenberg TS. Basal and morphine-evoked dopaminergic neurotransmission in the nucleus accumbens of MOR- and DOR-knockout mice. The European Journal of Neuroscience. 18: 1915-22. PMID 14622224 DOI: 10.1046/J.1460-9568.2003.02912.X |
0.442 |
|
| 2003 |
Berrendero F, Mendizábal V, Murtra P, Kieffer BL, Maldonado R. Cannabinoid receptor and WIN 55 212-2-stimulated [35S]-GTPgammaS binding in the brain of mu-, delta- and kappa-opioid receptor knockout mice. The European Journal of Neuroscience. 18: 2197-202. PMID 14622180 DOI: 10.1046/J.1460-9568.2003.02951.X |
0.564 |
|
| 2003 |
Lutfy K, Eitan S, Bryant CD, Yang YC, Saliminejad N, Walwyn W, Kieffer BL, Takeshima H, Carroll FI, Maidment NT, Evans CJ. Buprenorphine-induced antinociception is mediated by mu-opioid receptors and compromised by concomitant activation of opioid receptor-like receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10331-7. PMID 14614092 DOI: 10.1523/Jneurosci.23-32-10331.2003 |
0.549 |
|
| 2003 |
Li Y, Eitan S, Wu J, Evans CJ, Kieffer B, Sun X, Polakiewicz RD. Morphine induces desensitization of insulin receptor signaling. Molecular and Cellular Biology. 23: 6255-66. PMID 12917346 DOI: 10.1128/Mcb.23.17.6255-6266.2003 |
0.396 |
|
| 2003 |
Jamot L, Matthes HW, Simonin F, Kieffer BL, Roder JC. Differential involvement of the mu and kappa opioid receptors in spatial learning. Genes, Brain, and Behavior. 2: 80-92. PMID 12884965 DOI: 10.1034/J.1601-183X.2003.00013.X |
0.435 |
|
| 2003 |
Décaillot FM, Befort K, Filliol D, Yue S, Walker P, Kieffer BL. Opioid receptor random mutagenesis reveals a mechanism for G protein-coupled receptor activation. Nature Structural Biology. 10: 629-36. PMID 12847517 DOI: 10.1038/Nsb950 |
0.44 |
|
| 2003 |
Morinville A, Cahill CM, Esdaile MJ, Aibak H, Collier B, Kieffer BL, Beaudet A. Regulation of delta-opioid receptor trafficking via mu-opioid receptor stimulation: evidence from mu-opioid receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4888-98. PMID 12832511 |
0.428 |
|
| 2003 |
Philippe D, Dubuquoy L, Groux H, Brun V, Chuoï-Mariot MT, Gaveriaux-Ruff C, Colombel JF, Kieffer BL, Desreumaux P. Anti-inflammatory properties of the mu opioid receptor support its use in the treatment of colon inflammation. The Journal of Clinical Investigation. 111: 1329-38. PMID 12727924 DOI: 10.1172/Jci16750 |
0.448 |
|
| 2003 |
Oakley SM, Toth G, Borsodi A, Kieffer BL, Kitchen I. G-protein coupling of delta-opioid receptors in brains of mu-opioid receptor knockout mice. European Journal of Pharmacology. 466: 91-8. PMID 12679145 DOI: 10.1016/S0014-2999(03)01531-0 |
0.549 |
|
| 2003 |
Koob GF, Roberts AJ, Kieffer BL, Heyser CJ, Katner SN, Ciccocioppo R, Weiss F. Animal models of motivation for drinking in rodents with a focus on opioid receptor neuropharmacology. Recent Developments in Alcoholism : An Official Publication of the American Medical Society On Alcoholism, the Research Society On Alcoholism, and the National Council On Alcoholism. 16: 263-81. PMID 12638642 |
0.515 |
|
| 2003 |
Martin M, Matifas A, Maldonado R, Kieffer BL. Acute antinociceptive responses in single and combinatorial opioid receptor knockout mice: distinct mu, delta and kappa tones. The European Journal of Neuroscience. 17: 701-8. PMID 12603260 DOI: 10.1046/J.1460-9568.2003.02482.X |
0.526 |
|
| 2003 |
Castañé A, Robledo P, Matifas A, Kieffer BL, Maldonado R. Cannabinoid withdrawal syndrome is reduced in double mu and delta opioid receptor knockout mice. The European Journal of Neuroscience. 17: 155-9. PMID 12534979 DOI: 10.1046/J.1460-9568.2003.02409.X |
0.515 |
|
| 2003 |
Gavériaux-Ruff C, Simonin F, Filliol D, Kieffer BL. Enhanced humoral response in kappa-opioid receptor knockout mice. Journal of Neuroimmunology. 134: 72-81. PMID 12507774 DOI: 10.1016/S0165-5728(02)00419-8 |
0.493 |
|
| 2003 |
Morinville A, Cahill CM, Esdaile MJ, Aibak H, Collier B, Kieffer BL, Beaudet A. Regulation of δ-Opioid Receptor Trafficking via μ-Opioid Receptor Stimulation: Evidence from μ-Opioid Receptor Knock-Out Mice The Journal of Neuroscience. 23: 4888-4898. DOI: 10.1523/Jneurosci.23-12-04888.2003 |
0.427 |
|
| 2002 |
Berrendero F, Kieffer BL, Maldonado R. Attenuation of nicotine-induced antinociception, rewarding effects, and dependence in mu-opioid receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10935-40. PMID 12486188 DOI: 10.1523/Jneurosci.22-24-10935.2002 |
0.492 |
|
| 2002 |
Halab L, Becker JA, Darula Z, Tourwé D, Kieffer BL, Simonin F, Lubell WD. Probing opioid receptor interactions with azacycloalkane amino acids. Synthesis of a potent and selective ORL1 antagonist. Journal of Medicinal Chemistry. 45: 5353-7. PMID 12431062 DOI: 10.1021/Jm020078L |
0.399 |
|
| 2002 |
Gavériaux-Ruff C, Kieffer BL. Opioid receptor genes inactivated in mice: the highlights. Neuropeptides. 36: 62-71. PMID 12359497 DOI: 10.1054/Npep.2002.0900 |
0.559 |
|
| 2002 |
Goody RJ, Oakley SM, Filliol D, Kieffer BL, Kitchen I. Quantitative autoradiographic mapping of opioid receptors in the brain of delta-opioid receptor gene knockout mice. Brain Research. 945: 9-19. PMID 12113946 DOI: 10.1016/S0006-8993(02)02452-6 |
0.391 |
|
| 2002 |
Contarino A, Picetti R, Matthes HW, Koob GF, Kieffer BL, Gold LH. Lack of reward and locomotor stimulation induced by heroin in mu-opioid receptor-deficient mice. European Journal of Pharmacology. 446: 103-9. PMID 12098591 DOI: 10.1016/S0014-2999(02)01812-5 |
0.609 |
|
| 2002 |
Bailey A, Matthes H, Kieffer B, Slowe S, Hourani SM, Kitchen I. Quantitative autoradiography of adenosine receptors and NBTI-sensitive adenosine transporters in the brains and spinal cords of mice deficient in the mu-opioid receptor gene. Brain Research. 943: 68-79. PMID 12088840 DOI: 10.1016/S0006-8993(02)02536-2 |
0.395 |
|
| 2002 |
Massotte D, Brillet K, Kieffer BL, Milligan G. Agonists activate Gi1α or Gi2α fused to the human mu opioid receptor differently Journal of Neurochemistry. 81: 1372-1382. PMID 12068084 DOI: 10.1046/J.1471-4159.2002.00946.X |
0.401 |
|
| 2002 |
Kieffer BL, Gavériaux-Ruff C. Exploring the opioid system by gene knockout. Progress in Neurobiology. 66: 285-306. PMID 12015197 DOI: 10.1016/S0301-0082(02)00008-4 |
0.555 |
|
| 2002 |
Kieffer BL, Evans CJ. Opioid tolerance-in search of the holy grail. Cell. 108: 587-90. PMID 11893329 DOI: 10.1016/S0092-8674(02)00666-9 |
0.518 |
|
| 2002 |
Simonin F, Kieffer BL. Two faces for an opioid peptide--and more receptors for pain research. Nature Neuroscience. 5: 185-6. PMID 11865303 DOI: 10.1038/Nn0302-185 |
0.439 |
|
| 2002 |
Ghozland S, Matthes HW, Simonin F, Filliol D, Kieffer BL, Maldonado R. Motivational effects of cannabinoids are mediated by mu-opioid and kappa-opioid receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1146-54. PMID 11826143 |
0.47 |
|
| 2002 |
Ghozland S, Matthes HWD, Simonin F, Filliol D, Kieffer BL, Maldonado R. Motivational Effects of Cannabinoids Are Mediated by μ-Opioid and κ-Opioid Receptors The Journal of Neuroscience. 22: 1146-1154. DOI: 10.1523/JNEUROSCI.22-03-01146.2002 |
0.413 |
|
| 2001 |
Sarton E, Teppema L, Nieuwenhuijs D, Matthes HW, Kieffer B, Dahan A. Opioid effect on breathing frequency and thermogenesis in mice lacking exon 2 of the mu-opioid receptor gene. Advances in Experimental Medicine and Biology. 499: 399-404. PMID 11729915 DOI: 10.1007/978-1-4615-1375-9_64 |
0.524 |
|
| 2001 |
Sarton E, Teppema LJ, Olievier C, Nieuwenhuijs D, Matthes HW, Kieffer BL, Dahan A. The involvement of the mu-opioid receptor in ketamine-induced respiratory depression and antinociception. Anesthesia and Analgesia. 93: 1495-500, table of c. PMID 11726430 DOI: 10.1097/00000539-200112000-00031 |
0.509 |
|
| 2001 |
Skoubis PD, Matthes HW, Walwyn WM, Kieffer BL, Maidment NT. Naloxone fails to produce conditioned place aversion in mu-opioid receptor knock-out mice. Neuroscience. 106: 757-63. PMID 11682161 DOI: 10.1016/S0306-4522(01)00333-5 |
0.459 |
|
| 2001 |
Zhou L, Rowley DL, Mi QS, Sefcovic N, Matthes HW, Kieffer BL, Donovan DM. Murine inter-strain polymorphisms alter gene targeting frequencies at the mu opioid receptor locus in embryonic stem cells. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 12: 772-8. PMID 11668392 DOI: 10.1007/s00335-001-1003-8 |
0.36 |
|
| 2001 |
Slowe SJ, Clarke S, Lena I, Goody RJ, Lattanzi R, Negri L, Simonin F, Matthes HW, Filliol D, Kieffer BL, Kitchen I. Autoradiographic mapping of the opioid receptor-like 1 (ORL1) receptor in the brains of mu-, delta- or kappa-opioid receptor knockout mice. Neuroscience. 106: 469-80. PMID 11591451 DOI: 10.1016/S0306-4522(01)00308-6 |
0.47 |
|
| 2001 |
Roberts AJ, Gold LH, Polis I, McDonald JS, Filliol D, Kieffer BL, Koob GF. Increased ethanol self-administration in delta-opioid receptor knockout mice. Alcoholism, Clinical and Experimental Research. 25: 1249-56. PMID 11584142 DOI: 10.1111/J.1530-0277.2001.Tb02344.X |
0.577 |
|
| 2001 |
Gavériaux-Ruff C, Filliol D, Simonin F, Matthes HW, Kieffer BL. Immunosuppression by delta-opioid antagonist naltrindole: delta- and triple mu/delta/kappa-opioid receptor knockout mice reveal a nonopioid activity. The Journal of Pharmacology and Experimental Therapeutics. 298: 1193-8. PMID 11504820 |
0.436 |
|
| 2001 |
Dahan A, Sarton E, Teppema L, Olievier C, Nieuwenhuijs D, Matthes HW, Kieffer BL. Anesthetic potency and influence of morphine and sevoflurane on respiration in mu-opioid receptor knockout mice. Anesthesiology. 94: 824-32. PMID 11388534 DOI: 10.1097/00000542-200105000-00021 |
0.502 |
|
| 2001 |
Morin-Surun MP, Boudinot E, Dubois C, Matthes HW, Kieffer BL, Denavit-Saubié M, Champagnat J, Foutz AS. Respiratory function in adult mice lacking the mu-opioid receptor: role of delta-receptors. The European Journal of Neuroscience. 13: 1703-10. PMID 11359522 DOI: 10.1046/J.0953-816X.2001.01547.X |
0.542 |
|
| 2001 |
Maldonado R, Severini C, Matthes HW, Kieffer BL, Melchiorri P, Negri L. Activity of mu- and delta-opioid agonists in vas deferens from mice deficient in MOR gene. British Journal of Pharmacology. 132: 1485-92. PMID 11264242 DOI: 10.1038/sj.bjp.0703966 |
0.44 |
|
| 2001 |
Simonin F, Slowe S, Becker JA, Matthes HW, Filliol D, Chluba J, Kitchen I, Kieffer BL. Analysis of [3H]bremazocine binding in single and combinatorial opioid receptor knockout mice. European Journal of Pharmacology. 414: 189-95. PMID 11239918 DOI: 10.1016/S0014-2999(01)00822-6 |
0.405 |
|
| 2001 |
Hutcheson DM, Matthes HW, Valjent E, Sánchez-Blázquez P, RodrÃguez-DÃaz M, Garzón J, Kieffer BL, Maldonado R. Lack of dependence and rewarding effects of deltorphin II in mu-opioid receptor-deficient mice. The European Journal of Neuroscience. 13: 153-61. PMID 11135013 DOI: 10.1046/j.1460-9568.2001.01363.x |
0.356 |
|
| 2001 |
Befort K, Filliol D, Decaillot FM, Gaveriaux-Ruff C, Hoehe MR, Kieffer BL. A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling. The Journal of Biological Chemistry. 276: 3130-7. PMID 11067846 DOI: 10.1074/jbc.M006352200 |
0.391 |
|
| 2000 |
Kieffer BL. Opioid receptors: from genes to mice. The Journal of Pain : Official Journal of the American Pain Society. 1: 45-50. PMID 14622842 DOI: 10.1054/jpai.2000.9823 |
0.489 |
|
| 2000 |
Bigoni R, Rizzi A, Rizzi D, Becker JA, Kieffer BL, Simonin F, Regoli D, Calo G. In vitro pharmacological profile of peptide III-BTD: a novel ligand for nociceptin/orphanin FQ and opioid receptors. Life Sciences. 68: 233-9. PMID 11191640 DOI: 10.1016/S0024-3205(00)00931-0 |
0.3 |
|
| 2000 |
Roberts AJ, McDonald JS, Heyser CJ, Kieffer BL, Matthes HW, Koob GF, Gold LH. mu-Opioid receptor knockout mice do not self-administer alcohol. The Journal of Pharmacology and Experimental Therapeutics. 293: 1002-8. PMID 10869404 |
0.351 |
|
| 2000 |
Noble F, Szücs M, Kieffer B, Roques BP. Overexpression of dynamin is induced by chronic stimulation of mu- but not delta-opioid receptors: relationships with mu-related morphine dependence. Molecular Pharmacology. 58: 159-66. PMID 10860938 DOI: 10.1124/Mol.58.1.159 |
0.536 |
|
| 2000 |
Filliol D, Ghozland S, Chluba J, Martin M, Matthes HW, Simonin F, Befort K, Gavériaux-Ruff C, Dierich A, LeMeur M, Valverde O, Maldonado R, Kieffer BL. Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses. Nature Genetics. 25: 195-200. PMID 10835636 DOI: 10.1038/76061 |
0.476 |
|
| 2000 |
Monory K, Bourin MC, Spetea M, Tömböly C, Tóth G, Matthes HW, Kieffer BL, Hanoune J, Borsodi A. Specific activation of the mu opioid receptor (MOR) by endomorphin 1 and endomorphin 2. The European Journal of Neuroscience. 12: 577-84. PMID 10712637 DOI: 10.1046/J.1460-9568.2000.00936.X |
0.449 |
|
| 1999 |
Becker JA, Wallace A, Garzon A, Ingallinella P, Bianchi E, Cortese R, Simonin F, Kieffer BL, Pessi A. Ligands for kappa-opioid and ORL1 receptors identified from a conformationally constrained peptide combinatorial library. The Journal of Biological Chemistry. 274: 27513-22. PMID 10488086 DOI: 10.1074/Jbc.274.39.27513 |
0.425 |
|
| 1999 |
Kieffer BL. Opioids: first lessons from knockout mice. Trends in Pharmacological Sciences. 20: 19-26. PMID 10101958 DOI: 10.1016/S0165-6147(98)01279-6 |
0.445 |
|
| 1999 |
Stanasila L, Massotte D, Kieffer BL, Pattus F. Expression of delta, kappa and mu human opioid receptors in Escherichia coli and reconstitution of the high-affinity state for agonist with heterotrimeric G proteins. European Journal of Biochemistry / Febs. 260: 430-8. PMID 10095778 DOI: 10.1046/j.1432-1327.1999.00187.x |
0.376 |
|
| 1999 |
Slowe SJ, Simonin F, Kieffer B, Kitchen I. Quantitative autoradiography of mu-,delta- and kappa1 opioid receptors in kappa-opioid receptor knockout mice. Brain Research. 818: 335-45. PMID 10082819 DOI: 10.1016/S0006-8993(98)01201-3 |
0.454 |
|
| 1998 |
Massotte D, Kieffer BL. A molecular basis for opiate action. Essays in Biochemistry. 33: 65-77. PMID 10488442 DOI: 10.1042/Bse0330065 |
0.534 |
|
| 1998 |
René F, Muller A, Jover E, Kieffer B, Koch B, Loeffler J. Melanocortin receptors and δ‐opioid receptor mediate opposite signalling actions of POMC‐derived peptides in CATH.a cells European Journal of Neuroscience. 10: 1885-1894. PMID 9751158 DOI: 10.1046/J.1460-9568.1998.00199.X |
0.384 |
|
| 1998 |
Matthes HW, Smadja C, Valverde O, Vonesch JL, Foutz AS, Boudinot E, Denavit-Saubié M, Severini C, Negri L, Roques BP, Maldonado R, Kieffer BL. Activity of the delta-opioid receptor is partially reduced, whereas activity of the kappa-receptor is maintained in mice lacking the mu-receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 7285-95. PMID 9736649 |
0.469 |
|
| 1998 |
Gavériaux-Ruff C, Matthes HW, Peluso J, Kieffer BL. Abolition of morphine-immunosuppression in mice lacking the mu-opioid receptor gene. Proceedings of the National Academy of Sciences of the United States of America. 95: 6326-30. PMID 9600964 DOI: 10.1073/Pnas.95.11.6326 |
0.533 |
|
| 1998 |
Simonin F, Valverde O, Smadja C, Slowe S, Kitchen I, Dierich A, Le Meur M, Roques BP, Maldonado R, Kieffer BL. Disruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50,488H and attenuates morphine withdrawal. The Embo Journal. 17: 886-97. PMID 9463367 DOI: 10.1093/Emboj/17.4.886 |
0.48 |
|
| 1998 |
Valverde O, Maldonado R, Kieffer BL. Recent findings on the mechanism of action of morphine: Implications for the development of new analgesics Cns Drugs. 10: 1-10. DOI: 10.2165/00023210-199810010-00001 |
0.521 |
|
| 1998 |
Hoehe MR, Wendel B, Köpke K, Flachmeier C, Kieffer BL, Berrettini WH, Church GM. Genetic variability of the human mu opioid receptor gene and its implication for substance abuse American Journal of Medical Genetics - Neuropsychiatric Genetics. 81: 507. |
0.353 |
|
| 1997 |
Kitchen I, Slowe SJ, Matthes HW, Kieffer B. Quantitative autoradiographic mapping of mu-, delta- and kappa-opioid receptors in knockout mice lacking the mu-opioid receptor gene. Brain Research. 778: 73-88. PMID 9462879 DOI: 10.1016/S0006-8993(97)00988-8 |
0.469 |
|
| 1997 |
Gavériaux-Ruff C, Peluso J, Befort K, Simonin F, Zilliox C, Kieffer BL. Detection of opioid receptor mRNA by RT-PCR reveals alternative splicing for the delta- and kappa-opioid receptors. Brain Research. Molecular Brain Research. 48: 298-304. PMID 9332727 DOI: 10.1016/S0169-328X(97)00109-5 |
0.385 |
|
| 1997 |
Arttamangkul S, Ishmael JE, Murray TF, Grandy DK, DeLander GE, Kieffer BL, Aldrich JV. Synthesis and opioid activity of conformationally constrained dynorphin A analogues. 2. Conformational constraint in the "address" sequence. Journal of Medicinal Chemistry. 40: 1211-8. PMID 9111295 DOI: 10.1021/jm960753p |
0.305 |
|
| 1997 |
Kieffer B, Matthes H, Maldonado R. Mécanisme d'action de la morphine M S-Medecine Sciences. 13: 232-235. DOI: 10.4267/10608/344 |
0.321 |
|
| 1997 |
Befort K, Kieffer BL. Structure-activity relationships in the δ-opioid receptor Pain Reviews. 4: 100-121. |
0.376 |
|
| 1996 |
Befort K, Tabbara L, Kieffer BL. [35S]GTP gamma S binding: a tool to evaluate functional activity of a cloned opioid receptor transiently expressed in COS cells. Neurochemical Research. 21: 1301-7. PMID 8947920 |
0.355 |
|
| 1996 |
Matthes HW, Maldonado R, Simonin F, Valverde O, Slowe S, Kitchen I, Befort K, Dierich A, Le Meur M, Dollé P, Tzavara E, Hanoune J, Roques BP, Kieffer BL. Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature. 383: 819-23. PMID 8893006 DOI: 10.1038/383819A0 |
0.449 |
|
| 1995 |
Kieffer BL. Recent advances in molecular recognition and signal transduction of active peptides: receptors for opioid peptides. Cellular and Molecular Neurobiology. 15: 615-35. PMID 8719033 DOI: 10.1007/Bf02071128 |
0.465 |
|
| 1995 |
Pei G, Kieffer BL, Lefkowitz RJ, Freedman NJ. Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C. Molecular Pharmacology. 48: 173-7. PMID 7651349 |
0.326 |
|
| 1995 |
Gavériaux C, Peluso J, Simonin F, Laforet J, Kieffer B. Identification of kappa- and delta-opioid receptor transcripts in immune cells. Febs Letters. 369: 272-6. PMID 7649271 DOI: 10.1016/0014-5793(95)00766-3 |
0.438 |
|
| 1995 |
Simonin F, Gavériaux-Ruff C, Befort K, Matthes H, Lannes B, Micheletti G, Mattéi MG, Charron G, Bloch B, Kieffer B. kappa-Opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 92: 7006-10. PMID 7624359 DOI: 10.1073/Pnas.92.15.7006 |
0.503 |
|
| 1995 |
Nappey V, Butour J, Moisand C, Gaveriaux-Ruff C, Kieffer B, Mollereau C, Meunier J. ENKEPHALIN-INDUCED DESENSITIZATION OF ADENYLATE CYCLASE IN RECOMBINANT CV CELLS EXPRESSING A MOUSE δ-OPIOID RECEPTOR Analgesia. 1: 603-606. DOI: 10.3727/107156995819563771 |
0.408 |
|
| 1994 |
Kieffer BL, Befort K, Gavériaux-Ruff C, Hirth CG. The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. Proceedings of the National Academy of Sciences of the United States of America. 91: 1193. PMID 8302853 |
0.376 |
|
| 1994 |
Moine CL, Kieffer B, Gaveriaux-Ruff C, Befort K, Block B. Delta-opioid receptor gene expression in the mouse forebrain: localization in cholinergic neurons of the striatum. Neuroscience. 62: 635-640. PMID 7870294 DOI: 10.1016/0306-4522(94)90464-2 |
0.51 |
|
| 1994 |
Simonin F, Befort K, Gavériaux-Ruff C, Matthes H, Nappey V, Lannes B, Micheletti G, Kieffer B. Molecular characterization of the human δ-opioid receptor Regulatory Peptides. 54: 279-280. DOI: 10.1016/0167-0115(94)90498-7 |
0.485 |
|
| 1994 |
Gavériaux-Ruff C, Simonin F, Peluso J, Befort K, Kieffer B. Expression of opioid receptors mRNAs in immune cells Regulatory Peptides. 54: 103-104. DOI: 10.1016/0167-0115(94)90410-3 |
0.487 |
|
| 1994 |
Kieffer BL, Befort K, Gavériaux-Ruff C, Mattéi MG, Hirth C. Expression cloning of a murine delta opioid receptor Regulatory Peptides. 53: S1-S2. DOI: 10.1016/0167-0115(94)90211-9 |
0.444 |
|
| 1994 |
Kieffer B, Befort K, Simonin F, Matthes H, Gavériaux-Ruff C, Mattéi M, Hirth C. Molecular characterization of opioid receptors Neuropeptides. 26: 2. DOI: 10.1016/0143-4179(94)90138-4 |
0.468 |
|
| 1994 |
Simon EJ, Evans CJ, Kieffer BL, Childers SR, Uhl G, Yu L. Opioid receptors: Molecular and structural studies Nida Research Monograph Series. 46-50. |
0.382 |
|
| 1993 |
Dascal N, Schreibmayer W, Lim NF, Wang W, Chavkin C, DiMagno L, Labarca C, Kieffer BL, Gaveriaux-Ruff C, Trollinger D. Atrial G protein-activated K+ channel: expression cloning and molecular properties. Proceedings of the National Academy of Sciences of the United States of America. 90: 10235-9. PMID 8234283 DOI: 10.1073/Pnas.90.21.10235 |
0.308 |
|
| 1992 |
Kieffer BL, Befort K, Gaveriaux-Ruff C, Hirth CG. The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. Proceedings of the National Academy of Sciences of the United States of America. 89: 12048-52. PMID 1334555 DOI: 10.1073/Pnas.89.24.12048 |
0.432 |
|
| 1986 |
Kieffer B, Goeldner M, Hirth C, Aebersold R, Chang JY. Sequence determination of a peptide fragment from electric eel acetylcholinesterase, involved in the binding of quaternary ammonium Febs Letters. 202: 91-96. DOI: 10.1016/0014-5793(86)80655-X |
0.456 |
|
| 1981 |
Kieffer BL, Goeldner MP, Hirth CG. Aryldiazonium salts as photo-affinity labelling reagents for proteins Journal of the Chemical Society, Chemical Communications. 398-399. DOI: 10.1039/C39810000398 |
0.527 |
|
| Show low-probability matches. |