Jorge J. Palop - Publications

Gladstone and UCSF, San Francisco, CA, United States 
Alzheimer's Disease

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Johnson ECB, Ho K, Yu GQ, Das M, Sanchez PE, Djukic B, Lopez I, Yu X, Gill M, Zhang W, Paz JT, Palop JJ, Mucke L. Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1. Molecular Neurodegeneration. 15: 53. PMID 32921309 DOI: 10.1186/S13024-020-00393-5  1
2020 Davis EJ, Broestl L, Abdulai-Saiku S, Worden K, Bonham LW, Miñones-Moyano E, Moreno AJ, Wang D, Chang K, Williams G, Garay BI, Lobach I, Devidze N, Kim D, Anderson-Bergman C, ... ... Palop JJ, et al. A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease. Science Translational Medicine. 12. PMID 32848093 DOI: 10.1126/Scitranslmed.Aaz5677  1
2020 Hanson JE, Ma K, Elstrott J, Weber M, Saillet S, Khan AS, Simms J, Liu B, Kim TA, Yu GQ, Chen Y, Wang TM, Jiang Z, Liederer BM, Deshmukh G, ... ... Palop JJ, et al. GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models. Cell Reports. 30: 381-396.e4. PMID 31940483 DOI: 10.1016/J.Celrep.2019.12.030  0.8
2019 Ma K, Martinez-Losa MM, Xue Y, Khan A, Ho K, Dodart J, Jerecic J, Cobos I, Palop JJ. P2-063: SOLUBLE Aβ-OLIGOMER-SELECTIVE ANTIBODY ACU-3B3 REDUCES AMYLOID PATHOLOGY AND IMPROVES MULTIPLE BEHAVIORAL DOMAINS IN A MOUSE MODEL OF ALZHEIMER'S DISEASE Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2470  0.32
2018 Martinez-Losa M, Tracy TE, Ma K, Verret L, Clemente-Perez A, Khan AS, Cobos I, Ho K, Gan L, Mucke L, Alvarez-Dolado M, Palop JJ. Nav1.1-Overexpressing Interneuron Transplants Restore Brain Rhythms and Cognition in a Mouse Model of Alzheimer's Disease. Neuron. PMID 29551491 DOI: 10.1016/J.Neuron.2018.02.029  1
2016 Palop JJ, Mucke L. Network abnormalities and interneuron dysfunction in Alzheimer disease. Nature Reviews. Neuroscience. PMID 27829687 DOI: 10.1038/Nrn.2016.141  1
2015 Schachtrup C, Ryu JK, Mammadzada K, Khan AS, Carlton PM, Perez A, Christian F, Le Moan N, Vagena E, Baeza-Raja B, Rafalski V, Chan JP, Nitschke R, Houslay MD, Ellisman MH, ... ... Palop JJ, et al. Nuclear pore complex remodeling by p75(NTR) cleavage controls TGF-β signaling and astrocyte functions. Nature Neuroscience. PMID 26120963 DOI: 10.1038/Nn.4054  0.32
2013 Heng MY, Lin ST, Verret L, Huang Y, Kamiya S, Padiath QS, Tong Y, Palop JJ, Huang EJ, Ptáček LJ, Fu YH. Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model. The Journal of Clinical Investigation. 123: 2719-29. PMID 23676464 DOI: 10.1172/Jci66737  1
2012 Sanchez PE, Zhu L, Verret L, Vossel KA, Orr AG, Cirrito JR, Devidze N, Ho K, Yu GQ, Palop JJ, Mucke L. Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model. Proceedings of the National Academy of Sciences of the United States of America. 109: E2895-903. PMID 22869752 DOI: 10.1073/Pnas.1121081109  1
2012 Verret L, Mann EO, Hang GB, Barth AM, Cobos I, Ho K, Devidze N, Masliah E, Kreitzer AC, Mody I, Mucke L, Palop JJ. Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. Cell. 149: 708-21. PMID 22541439 DOI: 10.1016/J.Cell.2012.02.046  1
2011 Roberson ED, Halabisky B, Yoo JW, Yao J, Chin J, Yan F, Wu T, Hamto P, Devidze N, Yu GQ, Palop JJ, Noebels JL, Mucke L. Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 700-11. PMID 21228179 DOI: 10.1523/Jneurosci.4152-10.2011  1
2011 Palop JJ, Mucke L, Roberson ED. Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease: depletion of calcium-dependent proteins and inhibitory hippocampal remodeling. Methods in Molecular Biology (Clifton, N.J.). 670: 245-62. PMID 20967595 DOI: 10.1007/978-1-60761-744-0_17  1
2011 Palop JJ, Roberson ED, Cobos I. Step-by-step in situ hybridization method for localizing gene expression changes in the brain. Methods in Molecular Biology (Clifton, N.J.). 670: 207-30. PMID 20967593 DOI: 10.1007/978-1-60761-744-0_15  1
2010 Harris JA, Devidze N, Verret L, Ho K, Halabisky B, Thwin MT, Kim D, Hamto P, Lo I, Yu GQ, Palop JJ, Masliah E, Mucke L. Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network. Neuron. 68: 428-41. PMID 21040845 DOI: 10.1016/J.Neuron.2010.10.020  1
2010 Peebles CL, Yoo J, Thwin MT, Palop JJ, Noebels JL, Finkbeiner S. Arc regulates spine morphology and maintains network stability in vivo. Proceedings of the National Academy of Sciences of the United States of America. 107: 18173-8. PMID 20921410 DOI: 10.1073/Pnas.1006546107  1
2010 Buttini M, Masliah E, Yu GQ, Palop JJ, Chang S, Bernardo A, Lin C, Wyss-Coray T, Huang Y, Mucke L. Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice. The American Journal of Pathology. 177: 563-9. PMID 20595630 DOI: 10.2353/Ajpath.2010.090973  1
2010 Palop JJ, Mucke L. Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks. Nature Neuroscience. 13: 812-8. PMID 20581818 DOI: 10.1038/Nn.2583  1
2010 Gittis AH, Nelson AB, Thwin MT, Palop JJ, Kreitzer AC. Distinct roles of GABAergic interneurons in the regulation of striatal output pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2223-34. PMID 20147549 DOI: 10.1523/Jneurosci.4870-09.2010  1
2010 Palop JJ, Mucke L. Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: two faces of the same coin? Neuromolecular Medicine. 12: 48-55. PMID 19838821 DOI: 10.1007/S12017-009-8097-7  1
2009 Sun B, Halabisky B, Zhou Y, Palop JJ, Yu G, Mucke L, Gan L. Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease. Cell Stem Cell. 5: 624-33. PMID 19951690 DOI: 10.1016/J.Stem.2009.10.003  1
2009 Palop JJ, Mucke L. Epilepsy and cognitive impairments in Alzheimer disease. Archives of Neurology. 66: 435-40. PMID 19204149 DOI: 10.1001/Archneurol.2009.15  1
2008 Sanchez-Mejia RO, Newman JW, Toh S, Yu GQ, Zhou Y, Halabisky B, Cissé M, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L. Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nature Neuroscience. 11: 1311-8. PMID 18931664 DOI: 10.1038/Nn.2213  1
2008 Meilandt WJ, Yu GQ, Chin J, Roberson ED, Palop JJ, Wu T, Scearce-Levie K, Mucke L. Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5007-17. PMID 18463254 DOI: 10.1523/Jneurosci.0590-08.2008  1
2008 Deipolyi AR, Fang S, Palop JJ, Yu GQ, Wang X, Mucke L. Altered navigational strategy use and visuospatial deficits in hAPP transgenic mice. Neurobiology of Aging. 29: 253-66. PMID 17126954 DOI: 10.1016/J.Neurobiolaging.2006.10.021  1
2007 Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu GQ, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L. Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron. 55: 697-711. PMID 17785178 DOI: 10.1016/J.Neuron.2007.07.025  1
2007 Cheng IH, Scearce-Levie K, Legleiter J, Palop JJ, Gerstein H, Bien-Ly N, Puoliväli J, Lesné S, Ashe KH, Muchowski PJ, Mucke L. Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models. The Journal of Biological Chemistry. 282: 23818-28. PMID 17548355 DOI: 10.1074/Jbc.M701078200  1
2007 Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng IH, Wu T, Gerstein H, Yu GQ, Mucke L. Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science (New York, N.Y.). 316: 750-4. PMID 17478722 DOI: 10.1126/Science.1141736  1
2007 Chin J, Massaro CM, Palop JJ, Thwin MT, Yu GQ, Bien-Ly N, Bender A, Mucke L. Reelin depletion in the entorhinal cortex of human amyloid precursor protein transgenic mice and humans with Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2727-33. PMID 17360894 DOI: 10.1523/Jneurosci.3758-06.2007  1
2006 Nerín MA, Palop J, Montaño JA, Morandeira JR, Vázquez M. Acute mountain sickness: Influence of fluid intake Wilderness and Environmental Medicine. 17: 215-220. PMID 17219784  1
2006 Palop JJ, Chin J, Mucke L. A network dysfunction perspective on neurodegenerative diseases. Nature. 443: 768-73. PMID 17051202 DOI: 10.1038/Nature05289  1
2005 Chin J, Palop JJ, Puoliväli J, Massaro C, Bien-Ly N, Gerstein H, Scearce-Levie K, Masliah E, Mucke L. Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9694-703. PMID 16237174 DOI: 10.1523/Jneurosci.2980-05.2005  1
2005 Palop JJ, Chin J, Bien-Ly N, Massaro C, Yeung BZ, Yu GQ, Mucke L. Vulnerability of dentate granule cells to disruption of arc expression in human amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9686-93. PMID 16237173 DOI: 10.1523/Jneurosci.2829-05.2005  1
2004 Cheng IH, Palop JJ, Esposito LA, Bien-Ly N, Yan F, Mucke L. Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation. Nature Medicine. 10: 1190-2. PMID 15502844 DOI: 10.1038/Nm1123  1
2004 Chin J, Palop JJ, Yu GQ, Kojima N, Masliah E, Mucke L. Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4692-7. PMID 15140940 DOI: 10.1523/Jneurosci.0277-04.2004  1
2003 Palop JJ, Jones B, Kekonius L, Chin J, Yu GQ, Raber J, Masliah E, Mucke L. Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits. Proceedings of the National Academy of Sciences of the United States of America. 100: 9572-7. PMID 12881482 DOI: 10.1073/Pnas.1133381100  1
2002 López-García C, Varea E, Palop JJ, Nacher J, Ramirez C, Ponsoda X, Molowny A. Cytochemical techniques for zinc and heavy metals localization in nerve cells. Microscopy Research and Technique. 56: 318-31. PMID 11877810 DOI: 10.1002/Jemt.10037  1
2000 Nacher J, Palop JJ, Ramirez C, Molowny A, Lopez-Garcia C. Early histological maturation in the hippocampus of the guinea pig. Brain, Behavior and Evolution. 56: 38-44. PMID 11025343 DOI: 10.1159/000006676  1
1997 Sanchez-Andres JV, Palop JJ, Ramirez C, Nacher J, Molowny A, Lopez-Gracia C. Zinc-positive presynaptic boutons of the rabbit hippocampus during early postnatal development. Brain Research. Developmental Brain Research. 103: 171-83. PMID 9427481 DOI: 10.1016/S0165-3806(97)81793-2  1
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