David Colquhoun - Publications

Affiliations: 
University College London, London, United Kingdom 
Website:
http://www.ucl.ac.uk/Pharmacology/dc.html

166 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Sivilotti L, Colquhoun D. In praise of single channel kinetics. The Journal of General Physiology. PMID 27432998 DOI: 10.1085/jgp.201611649  1
2016 Smith K, Ernst E, Colquhoun D, Sampson W. 'Complementary & Alternative Medicine' (CAM): Ethical And Policy Issues. Bioethics. 30: 60-2. PMID 26806447 DOI: 10.1111/bioe.12243  1
2015 Colquhoun D. Response to comment by Loiselle & Ramchandra (2015). Royal Society Open Science. 2: 150319. PMID 26361560 DOI: 10.1098/rsos.150319  1
2014 Colquhoun D. An investigation of the false discovery rate and the misinterpretation of p-values. Royal Society Open Science. 1: 140216. PMID 26064558 DOI: 10.1098/rsos.140216  1
2014 Bewley S, Rose L, Gøtzsche P, Blennerhassett M, Colquhoun D, Pryke M, Tindall G, Braillon A, Richmond C, Illman J, May J. Time to halt an out of control trial with ineffective oversight. Bmj (Clinical Research Ed.). 349: g5601. PMID 25232068 DOI: 10.1136/bmj.g5601  1
2013 Colquhoun D, Novella SP. Acupuncture is theatrical placebo. Anesthesia and Analgesia. 116: 1360-3. PMID 23709076 DOI: 10.1213/ANE.0b013e31828f2d5e  1
2013 Colquhoun D. In Praise of Randomisation: The Importance of Causality in Medicine and its Subversion by Philosophers of Science Evidence, Inference and Enquiry. DOI: 10.5871/bacad/9780197264843.003.0012  1
2013 Colquhoun D. Alternative medicine: My part in its downfall European Review. 21: S62-S67. DOI: 10.1017/S1062798713000070  1
2012 Colquhoun D, Lape R. Perspectives on: conformational coupling in ion channels: allosteric coupling in ligand-gated ion channels. The Journal of General Physiology. 140: 599-612. PMID 23183696 DOI: 10.1085/jgp.201210844  1
2012 Colquhoun D. Scarcely credible treatments do not merit university attention. Bmj (Clinical Research Ed.). 344: e1628. PMID 22395936 DOI: 10.1136/bmj.e1628  1
2012 Lape R, Plested AJ, Moroni M, Colquhoun D, Sivilotti LG. The α1K276E startle disease mutation reveals multiple intermediate states in the gating of glycine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1336-52. PMID 22279218 DOI: 10.1523/JNEUROSCI.4346-11.2012  1
2012 Colquhoun D. Response to whitehead Bmj (Online). 345. DOI: 10.1136/bmj.e7088  1
2012 Gibb AJ, Edmonds B, Silver RA, Cull-Candy SG, Colquhoun D. Activation of NMDA receptors The Nmda Receptor. DOI: 10.1093/acprof:oso/9780192625021.003.0009  1
2011 Colquhoun D. Acupuncture for 'frequent attenders' with medically unexplained symptoms. The British Journal of General Practice : the Journal of the Royal College of General Practitioners. 61: 491. PMID 21801548 DOI: 10.3399/bjgp11X588268  1
2011 Colquhoun D. College of medicine is Prince's Foundation reincarnated. Bmj (Clinical Research Ed.). 343: d4368. PMID 21750061  1
2011 Holt S, Gilbey A, Colquhoun D, Baum M, Ernst E. Call for doctors not to practice homeopathy or refer to homeopaths. The New Zealand Medical Journal. 124: 87-8. PMID 21747430  1
2011 Colquhoun D. The A to Z of the wellbeing industry: from Angelic Reiki to patient centred care. Wellbeing is big business, but how much of it works? Bmj (Clinical Research Ed.). 342: d2711. PMID 21543407 DOI: 10.1136/bmj.d2711  1
2011 Krashia P, Lape R, Lodesani F, Colquhoun D, Sivilotti LG. The long activations of α2 glycine channels can be described by a mechanism with reaction intermediates ("flip"). The Journal of General Physiology. 137: 197-216. PMID 21282399 DOI: 10.1085/jgp.201010521  1
2011 Colquhoun D. College of Medicine: College of Medicine is Prince's Foundation reincarnated Bmj. 343. DOI: 10.1136/bmj.d4368  1
2011 Colquhoun D. Wilmshurst in context Prometheus (United Kingdom). 29: 89-90. DOI: 10.1080/08109028.2011.581794  1
2010 Colquhoun D. Homoeopathy debate: Author's reply to the minister Bmj (Online). 340: 279. DOI: 10.1136/bmj.c640  1
2009 Colquhoun D. Secret remedies: 100 years on. Bmj (Clinical Research Ed.). 339: b5432. PMID 20008972 DOI: 10.1136/bmj.b5432  1
2009 Lape R, Krashia P, Colquhoun D, Sivilotti LG. Agonist and blocking actions of choline and tetramethylammonium on human muscle acetylcholine receptors. The Journal of Physiology. 587: 5045-72. PMID 19752108 DOI: 10.1113/jphysiol.2009.176305  1
2009 Colquhoun D. Homoeopathic product licence. MHRA label seems to be illegal. Bmj (Clinical Research Ed.). 338: b2333. PMID 19509427 DOI: 10.1136/bmj.b2333  1
2009 Colquhoun D. The arrogance of trying to sum up abilities in a number. Nature. 458: 145. PMID 19279607 DOI: 10.1038/458145c  1
2009 Croxen R, Hatton C, Shelley C, Brydson M, Chauplannaz G, Oosterhuis H, Vincent A, Newsom-Davis J, Colquhoun D, Beeson D. Voluntary partial retraction of: Recessive inheritance and variable penetrance of slow-channel congenital myasthenic syndromes. Neurology. 72: 294. PMID 19153382 DOI: 10.1212/01.wnl.0000344248.36823.b5  1
2008 Colquhoun D. Colquhoun reply to chiropractic-defending letters from Kelly, Bale, and Roughan--and response from NZCA. The New Zealand Medical Journal. 121: 98-9; author reply 9. PMID 18797493  1
2008 Colquhoun D. Doctor Who? Inappropriate use of titles by some alternative "medicine" practitioners. The New Zealand Medical Journal. 121: 6-10. PMID 18670469  1
2008 Lape R, Colquhoun D, Sivilotti LG. On the nature of partial agonism in the nicotinic receptor superfamily. Nature. 454: 722-7. PMID 18633353 DOI: 10.1038/nature07139  1
2008 Colquhoun D. A very bad report on regulating complementary medicine. Bmj (Clinical Research Ed.). 337: a591; author reply a. PMID 18595905  1
2008 Shelley C, Colquhoun D. Corrigendum to A human congenital myasthenia-causing-mutation (eL78P) of the muscle nicotinic acetylcholine receptor with unusual single channel properties [J Physiol (2005) 564, 377-396] Journal of Physiology. 586: 5277-5277. DOI: 10.1113/jphysiol.2008.162628  1
2008 Colquhoun D. Response from David Colquhoun New Zealand Medical Journal. 121: 115-116.  1
2007 Colquhoun D. Why the Schild method is better than Schild realised. Trends in Pharmacological Sciences. 28: 608-14. PMID 18023486 DOI: 10.1016/j.tips.2007.09.011  1
2007 Colquhoun D. Science degrees without the science. Nature. 446: 373-4. PMID 17377563 DOI: 10.1038/446373a  1
2007 Colquhoun D. What have we learned from single ion channels? The Journal of Physiology. 581: 425-7. PMID 17363381 DOI: 10.1113/jphysiol.2007.131656  1
2007 Colquhoun D. Should NICE evaluate complementary and alternative medicines? Bmj (Clinical Research Ed.). 334: 507. PMID 17347234 DOI: 10.1136/bmj.39122.551250.BE  1
2007 Franck L, Chantler C, Dixon M, Colquhoun D. Should NICE evaluate complementary and alternative medicine? British Medical Journal. 334: 506-507. PMID 17347233  1
2007 Plested AJ, Groot-Kormelink PJ, Colquhoun D, Sivilotti LG. Single-channel study of the spasmodic mutation alpha1A52S in recombinant rat glycine receptors. The Journal of Physiology. 581: 51-73. PMID 17331994 DOI: 10.1113/jphysiol.2006.126920  1
2007 Colquhoun D. Treating critically ill patients with sugar pills. Chest. 131: 635-6; author reply . PMID 17296675 DOI: 10.1378/chest.06-2402  1
2007 Colquhoun D. What to do about CAM? [5] British Medical Journal. 335: 736.  1
2006 Colquhoun D. The quantitative analysis of drug-receptor interactions: a short history. Trends in Pharmacological Sciences. 27: 149-57. PMID 16483674 DOI: 10.1016/j.tips.2006.01.008  1
2006 Colquhoun D. Agonist-activated ion channels. British Journal of Pharmacology. 147: S17-26. PMID 16402101 DOI: 10.1038/sj.bjp.0706502  1
2005 Colquhoun D. From shut to open: what can we learn from linear free energy relationships? Biophysical Journal. 89: 3673-5. PMID 16319077 DOI: 10.1529/biophysj.105.071563  1
2005 Schorge S, Elenes S, Colquhoun D. Maximum likelihood fitting of single channel NMDA activity with a mechanism composed of independent dimers of subunits. The Journal of Physiology. 569: 395-418. PMID 16223763 DOI: 10.1113/jphysiol.2005.095349  1
2005 Colquhoun D, Persaud R, Konečni VJ, Musch DC, Fiske ST, Harris LT, Cuddy AJC. Abuse of prisoners at Abu Ghraib (multiple letters) [1] Science. 307: 1873-1875. PMID 15793899  1
2005 Shelley C, Colquhoun D. A human congenital myasthenia-causing mutation (epsilon L78P) of the muscle nicotinic acetylcholine receptor with unusual single channel properties. The Journal of Physiology. 564: 377-96. PMID 15731194 DOI: 10.1113/jphysiol.2004.081497  1
2005 Brands M, Colquhoun D. Homoeopathy: Relic of the past or medicine of the future? (Marking Samuel Hahnemann's 250th anniversary) Focus On Alternative and Complementary Therapies. 10: 278-280.  1
2005 Colquhoun D. Too many 'omics [4] Scientist. 19: 8.  1
2004 Burzomato V, Beato M, Groot-Kormelink PJ, Colquhoun D, Sivilotti LG. Single-channel behavior of heteromeric alpha1beta glycine receptors: an attempt to detect a conformational change before the channel opens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10924-40. PMID 15574743 DOI: 10.1523/JNEUROSCI.3424-04.2004  1
2004 Colquhoun D, Dowsland KA, Beato M, Plested AJ. How to impose microscopic reversibility in complex reaction mechanisms. Biophysical Journal. 86: 3510-8. PMID 15189850 DOI: 10.1529/biophysj.103.038679  1
2004 Colquhoun D, Sivilotti LG. Function and structure in glycine receptors and some of their relatives. Trends in Neurosciences. 27: 337-44. PMID 15165738 DOI: 10.1016/j.tins.2004.04.010  1
2004 Beato M, Groot-Kormelink PJ, Colquhoun D, Sivilotti LG. The activation mechanism of alpha1 homomeric glycine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 895-906. PMID 14749434 DOI: 10.1523/JNEUROSCI.4420-03.2004  1
2003 Beeson D, Webster R, Ealing J, Croxen R, Brownlow S, Brydson M, Newsom-Davis J, Slater C, Hatton C, Shelley C, Colquhoun D, Vincent A. Structural abnormalities of the AChR caused by mutations underlying congenital myasthenic syndromes. Annals of the New York Academy of Sciences. 998: 114-24. PMID 14592868 DOI: 10.1196/annals.1254.013  1
2003 Colquhoun D. Challenging the tyranny of impact factors. Nature. 423: 479; discussion 480. PMID 12774093 DOI: 10.1038/423479a  1
2003 Schorge S, Colquhoun D. Studies of NMDA receptor function and stoichiometry with truncated and tandem subunits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1151-8. PMID 12598603  1
2003 Colquhoun D, Hatton CJ, Hawkes AG. The quality of maximum likelihood estimates of ion channel rate constants. The Journal of Physiology. 547: 699-728. PMID 12562901 DOI: 10.1113/jphysiol.2002.034165  1
2003 Hatton CJ, Shelley C, Brydson M, Beeson D, Colquhoun D. Properties of the human muscle nicotinic receptor, and of the slow-channel myasthenic syndrome mutant epsilonL221F, inferred from maximum likelihood fits. The Journal of Physiology. 547: 729-60. PMID 12562900 DOI: 10.1113/jphysiol.2002.034173  1
2002 Croxen R, Hatton C, Shelley C, Brydson M, Chauplannaz G, Oosterhuis H, Vincent A, Newsom-Davis J, Colquhoun D, Beeson D. Recessive inheritance and variable penetrance of slow-channel congenital myasthenic syndromes. Neurology. 59: 162-8. PMID 12141316  1
2002 Beato M, Groot-Kormelink PJ, Colquhoun D, Sivilotti LG. Openings of the rat recombinant alpha 1 homomeric glycine receptor as a function of the number of agonist molecules bound. The Journal of General Physiology. 119: 443-66. PMID 11981023 DOI: 10.1085/jgp.20028530  1
2000 Anson LC, Schoepfer R, Colquhoun D, Wyllie DJ. Single-channel analysis of an NMDA receptor possessing a mutation in the region of the glutamate binding site. The Journal of Physiology. 527: 225-37. PMID 10970425  1
2000 Cheffings CM, Colquhoun D. Single channel analysis of a novel NMDA channel from Xenopus oocytes expressing recombinant NR1a, NR2A and NR2D subunits. The Journal of Physiology. 526: 481-91. PMID 10922001  1
1999 Colquhoun D. GABA and the single oocyte: relating binding to gating. Nature Neuroscience. 2: 201-2. PMID 10195208 DOI: 10.1038/6298  1
1999 Colquhoun D. Unfair exchange [5] Nature. 402: 230.  1
1998 Colquhoun D. Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. British Journal of Pharmacology. 125: 924-47. PMID 9846630  1
1998 Wyllie DJ, Béhé P, Colquhoun D. Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors. The Journal of Physiology. 510: 1-18. PMID 9625862 DOI: 10.1111/j.1469-7793.1998.001bz.x  1
1998 Groot-Kormelink PJ, Luyten WH, Colquhoun D, Sivilotti LG. A reporter mutation approach shows incorporation of the "orphan" subunit beta3 into a functional nicotinic receptor. The Journal of Biological Chemistry. 273: 15317-20. PMID 9624109 DOI: 10.1074/jbc.273.25.15317  1
1998 Colquhoun D, Sakmann B. From muscle endplate to brain synapses: a short history of synapses and agonist-activated ion channels. Neuron. 20: 381-7. PMID 9539116 DOI: 10.1016/S0896-6273(00)80982-4  1
1998 Lewis TM, Sivilotti LG, Colquhoun D, Gardiner RM, Schoepfer R, Rees M. Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes. The Journal of Physiology. 507: 25-40. PMID 9490812 DOI: 10.1111/j.1469-7793.1998.025bu.x  1
1998 Anson LC, Chen PE, Wyllie DJ, Colquhoun D, Schoepfer R. Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 581-9. PMID 9425000  1
1998 Colquhoun D. Binding, gating, affinity and efficacy: The interpretation of structure-activity relationships for agonists acid of the effects of mutating receptors British Journal of Pharmacology. 125: 923-947. DOI: 10.1038/sj.bjp.0702164  1
1997 Lewis TM, Harkness PC, Sivilotti LG, Colquhoun D, Millar NS. The ion channel properties of a rat recombinant neuronal nicotinic receptor are dependent on the host cell type. The Journal of Physiology. 505: 299-306. PMID 9423173 DOI: 10.1111/j.1469-7793.1997.299bb.x  1
1997 Sivilotti LG, McNeil DK, Lewis TM, Nassar MA, Schoepfer R, Colquhoun D. Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single-channel behaviour. The Journal of Physiology. 500: 123-38. PMID 9097938  1
1997 Colquhoun D, Hawkes AG, Merlushkin A, Edmonds B. Properties of single ion channel currents elicited by a pulse of agonist concentration or voltage Philosophical Transactions of the Royal Society a: Mathematical, Physical and Engineering Sciences. 355: 1743-1786.  1
1997 Colquhoun D. Worthless ranking [9] Nature. 386: 320.  1
1996 Wyllie DJ, Béhé P, Nassar M, Schoepfer R, Colquhoun D. Single-channel currents from recombinant NMDA NR1a/NR2D receptors expressed in Xenopus oocytes. Proceedings. Biological Sciences / the Royal Society. 263: 1079-86. PMID 8805841 DOI: 10.1098/rspb.1996.0159  1
1996 Silver RA, Colquhoun D, Cull-Candy SG, Edmonds B. Deactivation and desensitization of non-NMDA receptors in patches and the time course of EPSCs in rat cerebellar granule cells. The Journal of Physiology. 493: 167-73. PMID 8735702  1
1996 Colquhoun D, Hawkes AG, Srodzinski K. Joint distributions of apparent open and shut times of single-ion channels and maximum likelihood fitting of mechanisms Philosophical Transactions of the Royal Society a: Mathematical, Physical and Engineering Sciences. 354: 2555-2590.  1
1995 Fredkin DR, Rice JA, Colquhoun D, Gibb AJ. Persistence: a new statistic for characterizing ion-channel activity. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 350: 353-67. PMID 8602406 DOI: 10.1098/rstb.1995.0170  1
1995 Béhé P, Stern P, Wyllie DJ, Nassar M, Schoepfer R, Colquhoun D. Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors. Proceedings. Biological Sciences / the Royal Society. 262: 205-13. PMID 8524912 DOI: 10.1098/rspb.1995.0197  1
1995 Edmonds B, Gibb AJ, Colquhoun D. Mechanisms of activation of glutamate receptors and the time course of excitatory synaptic currents. Annual Review of Physiology. 57: 495-519. PMID 7778875 DOI: 10.1146/annurev.ph.57.030195.002431  1
1995 Sivilotti L, Colquhoun D. Acetylcholine receptors: too many channels, too few functions. Science (New York, N.Y.). 269: 1681-2. PMID 7569892  1
1995 Chen CC, Akopian AN, Sivilotti L, Colquhoun D, Burnstock G, Wood JN. A P2X purinoceptor expressed by a subset of sensory neurons. Nature. 377: 428-31. PMID 7566119 DOI: 10.1038/377428a0  1
1995 Connolly JG, Gibb AJ, Colquhoun D. Heterogeneity of neuronal nicotinic acetylcholine receptors in thin slices of rat medial habenula. The Journal of Physiology. 484: 87-105. PMID 7541465 DOI: 10.1113/jphysiol.1995.sp020650  1
1995 Edmonds B, Gibb AJ, Colquhoun D. Mechanisms of activation of muscle nicotinic acetylcholine receptors and the time course of endplate currents. Annual Review of Physiology. 57: 469-93. PMID 7539991 DOI: 10.1146/annurev.ph.57.030195.002345  1
1995 Colquhoun D, Hawkes AG. Desensitization of N-methyl-D-aspartate receptors: a problem of interpretation. Proceedings of the National Academy of Sciences of the United States of America. 92: 10327-9. PMID 7479777 DOI: 10.1073/pnas.92.22.10327  1
1994 Stern P, Cik M, Colquhoun D, Stephenson FA. Single channel properties of cloned NMDA receptors in a human cell line: comparison with results from Xenopus oocytes. The Journal of Physiology. 476: 391-7. PMID 8057248  1
1994 Covernton PJ, Kojima H, Sivilotti LG, Gibb AJ, Colquhoun D. Comparison of neuronal nicotinic receptors in rat sympathetic neurones with subunit pairs expressed in Xenopus oocytes. The Journal of Physiology. 481: 27-34. PMID 7853248  1
1993 Colquhoun D. Nonselective cation channels. Pharmacology, physiology and biophysics. Exs. 66: ix-x. PMID 7505642  1
1993 Colquhoun D, Farrant M. Molecular pharmacology. The binding issue. Nature. 366: 510-1. PMID 7504782 DOI: 10.1038/366510b0  1
1993 Stern P, Behe P, Schoepfer R, Colquhoun D. Single channel kinetics of recombinant NMDA receptors Journal of Physiology. 473: 48P.  1
1992 Edwards FA, Gibb AJ, Colquhoun D. ATP receptor-mediated synaptic currents in the central nervous system. Nature. 359: 144-7. PMID 1381811 DOI: 10.1038/359144a0  1
1992 Colquhoun D. Unravelling the paradox. Trends in Pharmacological Sciences. 13: 429-30. PMID 1363451 DOI: 10.1016/0165-6147(92)90137-U  1
1992 Colquhoun D, Jonas P, Sakmann B. Action of brief pulses of glutamate on AMPA/kainate receptors in patches from different neurones of rat hippocampal slices. The Journal of Physiology. 458: 261-87. PMID 1338788  1
1992 Gibb AJ, Colquhoun D. Activation of N-methyl-D-aspartate receptors by L-glutamate in cells dissociated from adult rat hippocampus. The Journal of Physiology. 456: 143-79. PMID 1293277 DOI: 10.1113/jphysiol.1992.sp019331  1
1992 Edmonds B, Colquhoun D. Rapid decay of averaged single-channel NMDA receptor activations recorded at low agonist concentration. Proceedings. Biological Sciences / the Royal Society. 250: 279-86. PMID 1283640 DOI: 10.1098/rspb.1992.0160  1
1992 Stern P, Béhé P, Schoepfer R, Colquhoun D. Single-channel conductances of NMDA receptors expressed from cloned cDNAs: comparison with native receptors. Proceedings. Biological Sciences / the Royal Society. 250: 271-7. PMID 1283639 DOI: 10.1098/rspb.1992.0159  1
1992 Hawkes AG, Jalali A, Colquhoun D. Asymptotic distributions of apparent open times and shut times in a single channel record allowing for the omission of brief events. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 337: 383-404. PMID 1279733 DOI: 10.1098/rstb.1992.0116  1
1992 Colquhoun D, Jonas P, Sakmann B. Differences in desensitization of glutamate receptor channels in three areas of rat hippocampus Journal of Physiology. 446: 547P.  1
1992 Colquhoun D, Jonas P, Sakmann B. Glutamate receptor channel activation following fast agonist application to patches from rat hippocampus CA1 and CA3 pyramidal cells Journal of Physiology. 446: 183P.  1
1991 Marshall CG, Ogden D, Colquhoun D. Activation of ion channels in the frog endplate by several analogues of acetylcholine. The Journal of Physiology. 433: 73-93. PMID 1726798  1
1991 Colquhoun D. Neher and Sakmann win Nobel Prize for patch-clamp work. Trends in Pharmacological Sciences. 12: 449. PMID 1724328  1
1991 Colquhoun D. Ion channels: this year's Nobel prize in physiology or medicine. Bmj (Clinical Research Ed.). 303: 938-9. PMID 1720062  1
1991 Mathie A, Cull-Candy SG, Colquhoun D. Conductance and kinetic properties of single nicotinic acetylcholine receptor channels in rat sympathetic neurones. The Journal of Physiology. 439: 717-50. PMID 1716680  1
1991 Newland CF, Colquhoun D, Cull-Candy SG. Single channels activated by high concentrations of GABA in superior cervical ganglion neurones of the rat. The Journal of Physiology. 432: 203-33. PMID 1715917  1
1991 Howe JR, Cull-Candy SG, Colquhoun D. Currents through single glutamate receptor channels in outside-out patches from rat cerebellar granule cells. The Journal of Physiology. 432: 143-202. PMID 1715916  1
1991 Gibb AJ, Colquhoun D. Glutamate activation of a single NMDA receptor-channel produces a cluster of channel openings. Proceedings. Biological Sciences / the Royal Society. 243: 39-45. PMID 1708142 DOI: 10.1098/rspb.1991.0007  1
1991 Colquhoun D. Trials of homeopathy [10] British Medical Journal. 302: 1466.  1
1990 Colquhoun D, Cachelin AB, Marshall CG, Mathie A, Ogden DC. Function of nicotinic synapses. Progress in Brain Research. 84: 43-50. PMID 2267314  1
1990 Marshall CG, Ogden DC, Colquhoun D. The actions of suxamethonium (succinyldicholine) as an agonist and channel blocker at the nicotinic receptor of frog muscle. The Journal of Physiology. 428: 155-74. PMID 2133043 DOI: 10.1113/jphysiol.1990.sp018205  1
1990 Colquhoun D. Re-analysis of clinical trial of homoeopathic treatment in fibrositis. Lancet (London, England). 336: 441-2. PMID 1974969 DOI: 10.1016/0140-6736(90)91989-N  1
1990 Gibb AJ, Kojima H, Carr JA, Colquhoun D. Expression of cloned receptor subunits produces multiple receptors. Proceedings. Biological Sciences / the Royal Society. 242: 108-12. PMID 1706096 DOI: 10.1098/rspb.1990.0112  1
1990 Mathie A, Colquhoun D, Cull-Candy SG. Rectification of currents activated by nicotinic acetylcholine receptors in rat sympathetic ganglion neurones. The Journal of Physiology. 427: 625-55. PMID 1698982  1
1990 Colquhoun D, Hawkes AG. Stochastic properties of ion channel openings and bursts in a membrane patch that contains two channels: evidence concerning the number of channels present when a record containing only single openings is observed. Proceedings of the Royal Society of London. Series B, Biological Sciences. 240: 453-77. PMID 1696014 DOI: 10.1098/rspb.1990.0048  1
1989 Cachelin AB, Colquhoun D. Desensitization of the acetylcholine receptor of frog end-plates measured in a Vaseline-gap voltage clamp. The Journal of Physiology. 415: 159-88. PMID 2561785  1
1989 Colquhoun D. Validity of the operational model Trends in Pharmacological Sciences. 10: 17. DOI: 10.1016/0165-6147(89)90100-4  1
1988 Colquhoun D. Single channel analysis costs time. Trends in Pharmacological Sciences. 9: 157-8. PMID 2470175 DOI: 10.1016/0165-6147(88)90027-2  1
1988 Colquhoun D, Ogden DC. Activation of ion channels in the frog end-plate by high concentrations of acetylcholine. The Journal of Physiology. 395: 131-59. PMID 2457675  1
1988 Howe JR, Colquhoun D, Cull-Candy SG. On the kinetics of large-conductance glutamate-receptor ion channels in rat cerebellar granule neurons. Proceedings of the Royal Society of London. Series B, Biological Sciences. 233: 407-22. PMID 2456583 DOI: 10.1098/rspb.1988.0030  1
1987 Mathie A, Cull-Candy SG, Colquhoun D. Single-channel and whole-cell currents evoked by acetylcholine in dissociated sympathetic neurons of the rat. Proceedings of the Royal Society of London. Series B, Biological Sciences. 232: 239-48. PMID 2892208  1
1987 Colquhoun D. Molecular neurobiology. A new type of ion-channel block. Nature. 329: 204-5. PMID 2442618 DOI: 10.1038/329204a0  1
1987 Colquhoun D, Hawkes AG. A note on correlations in single ion channel records. Proceedings of the Royal Society of London. Series B, Biological Sciences. 230: 15-52. PMID 2438700  1
1987 Ogden D, Colquhoun D, Gibb NA. Ogden et al. reply Trends in Pharmacological Sciences. 8: 335. DOI: 10.1016/0165-6147(87)90141-6  1
1987 Ogden DC, Colquhoun D, Gibb AJ. Regulation of the acetylcholine receptor Trends in Pharmacological Sciences. 8: 294-295. DOI: 10.1016/0165-6147(87)90120-9  1
1987 Colquhoun D, Ogden DC, Mathie A. Nicotinic acetylcholine receptors of nerve and muscle: Functional aspects Trends in Pharmacological Sciences. 8: 465-472. DOI: 10.1016/0165-6147(87)90040-X  1
1986 Colquhoun D. Molecular pharmacology: structure and function of acetylcholine-receptor ion channels. Nature. 321: 382-3. PMID 2423877 DOI: 10.1038/321382a0  1
1986 Colquhoun D. Caution: agonists are complex Trends in Pharmacological Sciences. 7: 390. DOI: 10.1016/0165-6147(86)90398-6  1
1986 Colquhoun D. Mechanism of action of the nicotinic acetylcholine receptor, Advanced Research Workshop, Island of Santorini, Greece. May 19-23, 1986 Trends in Pharmacological Sciences. 7: 292-294.  1
1985 Colquhoun D, Sakmann B. Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate. The Journal of Physiology. 369: 501-57. PMID 2419552 DOI: 10.1113/jphysiol.1985.sp015912  1
1985 Ogden DC, Colquhoun D. Ion channel block by acetylcholine, carbachol and suberyldicholine at the frog neuromuscular junction. Proceedings of the Royal Society of London. Series B, Biological Sciences. 225: 329-55. PMID 2414779  1
1985 Colquhoun D. Imprecision in presentation of binding studies Trends in Pharmacological Sciences. 6: 197. DOI: 10.1016/0165-6147(85)90092-6  1
1984 Gardner P, Ogden DC, Colquhoun D. Conductances of single ion channels opened by nicotinic agonists are indistinguishable. Nature. 309: 160-2. PMID 6325934 DOI: 10.1038/309160a0  1
1984 Ogden DC, Gray PT, Colquhoun D, Rang HP. Kinetics of acetylcholine activated ion channels in chick ciliary ganglion neurones grown in tissue culture. PflüGers Archiv : European Journal of Physiology. 400: 44-50. PMID 6324068 DOI: 10.1007/BF00670535  1
1984 Colquhoun D, Ogden DC. Evidence from single-channel recording of channel block by nicotinic agonists at the frog neuromuscular junction Journal of Physiology. 90P.  1
1983 Ogden DC, Colquhoun D. The efficacy of agonists at the frog neuromuscular junction studied with single channel recording. PflüGers Archiv : European Journal of Physiology. 399: 246-8. PMID 6318187 DOI: 10.1007/BF00656725  1
1982 Colquhoun D, Sheridan RE. The effect of tubocurarine competition on the kinetics of agonist action on the nicotinic receptor. British Journal of Pharmacology. 75: 77-86. PMID 6978750  1
1982 Colquhoun D, Hawkes AG. On the stochastic properties of bursts of single ion channel openings and of clusters of bursts. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 300: 1-59. PMID 6131450  1
1982 Rang HP, Colquhoun D, Rang HP. The action of ganglionic blocking drugs on the synaptic responses of rat submandibular ganglion cells. British Journal of Pharmacology. 75: 151-68. PMID 6122479  0.76
1981 Colquhoun D, Neher E, Reuter H, Stevens CF. Inward current channels activated by intracellular Ca in cultured cardiac cells. Nature. 294: 752-4. PMID 6275271  1
1981 Colquhoun D, Sakmann B. Fluctuations in the microsecond time range of the current through single acetylcholine receptor ion channels. Nature. 294: 464-6. PMID 6273743 DOI: 10.1038/294464a0  1
1981 Ogden DC, Siegelbaum SA, Colquhoun D. Block of acetylcholine-activated ion channels by an uncharged local anaesthetic. Nature. 289: 596-8. PMID 6258085 DOI: 10.1038/289596a0  1
1981 Colquhoun D, Hawkes AG. On the stochastic properties of single ion channels. Proceedings of the Royal Society of London. Series B, Biological Sciences. 211: 205-35. PMID 6111797  1
1981 Colquhoun D, Sheridan RE. The modes of action of gallamine. Proceedings of the Royal Society of London. Series B, Biological Sciences. 211: 181-203. PMID 6111796  1
1981 Colquhoun D. How fast do drugs work? Trends in Pharmacological Sciences. 2: 212-217. DOI: 10.1016/0165-6147(81)90316-3  1
1980 Colquhoun D, Sheridan RE. Kinetic effects of tubocurarine on skeletal muscle at high agonist concentrations [proceedings]. British Journal of Pharmacology. 68: 143P-144P. PMID 6965597  1
1980 Colquhoun D. Competitive block and ion channel block as mechanisms of antagonist action on the skeletal muscle end-plate. Advances in Biochemical Psychopharmacology. 21: 67-80. PMID 6246760  1
1979 Colquhoun D, Sheridan RE. Modes of action of gallamine at the neuromuscular junction [proceedings]. British Journal of Pharmacology. 66: 78P-79P. PMID 454963  1
1979 Colquhoun D, Dreyer F, Sheridan RE. The actions of tubocurarine at the frog neuromuscular junction. The Journal of Physiology. 293: 247-84. PMID 315462 DOI: 10.1113/jphysiol.1979.sp012888  1
1978 Colquhoun D, Dreyer F, Sheridan RE. The action of tubocurarine at the neuromuscular junction [proceedings]. The Journal of Physiology. 284: 171P-172P. PMID 310459  1
1978 Colquhoun D, Dreyer F, Sheridan RE. Is curare a competitive acetylcholine antagonist at the neuromuscular junction? Neuroscience Letters. 10.  1
1977 Colquhoun D, Large WA, Rang HP. An analysis of the action of a false transmitter at the neuromuscular junction. The Journal of Physiology. 266: 361-95. PMID 192885 DOI: 10.1113/jphysiol.1977.sp011772  1
1977 Colquhoun D, Hawkes AG. Relaxation and fluctuations of membrane currents that flow through drug-operated channels. Proceedings of the Royal Society of London. Series B, Biological Sciences. 199: 231-62. PMID 22856  1
1976 Colquhoun D. Analysis of end-plate current fluctuations produced by acetylcholine and acetylmonoethylcholine in rat muscle [proceedings]. British Journal of Pharmacology. 58: 428P-429P. PMID 990615  1
1976 Colquhoun D, Range HP. Effects of inhibitors of the binding of iodinated alpha-bungarotoxin to acetylcholine receptors in rat muscle. Molecular Pharmacology. 12: 519-35. PMID 958205  1
1975 Colquhoun D, Dionne VE, Steinbach JH, Stevens CF. Conductance of channels opened by acetylcholine-like drugs in muscle end-plate. Nature. 253: 204-6. PMID 1078602  1
1975 Colquhoun D. Mechanisms of drug action at the voluntary muscle endplate. Annual Review of Pharmacology. 15: 307-25. PMID 238463 DOI: 10.1146/annurev.pa.15.040175.001515  1
1974 Colquhoun D, Rang HP, Ritchie JM. The binding of tetrodotoxin and alpha-bungarotoxin to normal and denervated mammalian muscle. The Journal of Physiology. 240: 199-226. PMID 4854666 DOI: 10.1113/jphysiol.1974.sp010607  1
1974 Colquhoun D, Rang HP, Ritchie JM. Proceedings: Tetrodotoxin binding to innervated and denervated rat diaphragm homogenates. British Journal of Pharmacology. 51: 125P-126P. PMID 4441774  1
1974 Colquhoun D, Rang HP. Proceedings: The inhibition of alpha-bungarotoxin binding to denervated rat muscle by tubocurarine and other drugs. British Journal of Pharmacology. 51: 124P-125P. PMID 4441773  1
1973 Colquhoun D, Rang HP, Ritchie JM. The binding of labelled tetrodotoxin and cobra toxin by the rat diaphragm. British Journal of Pharmacology. 47: 632P-633P. PMID 4730848  1
1972 Colquhoun D, Ritchie JM. The kinetics of the interaction between tetrodotoxin and mammalian nonmyelinated nerve fibers. Molecular Pharmacology. 8: 285-92. PMID 5040931  1
1972 Colquhoun D, Henderson R, Ritchie JM. The binding of tritium-labelled tetrodotoxin to non-myelinated nerve. The Journal of Physiology. 224: 25P-26P. PMID 5039987  1
1972 Colquhoun D, Ritchie JM. The interaction at equilibrium between tetrodotoxin and mammalian non-myelinated nerve fibres. The Journal of Physiology. 221: 533-53. PMID 5016360 DOI: 10.1113/jphysiol.1972.sp009766  1
1972 Colquhoun D, Henderson R, Ritchie JM. The binding of labelled tetrodotoxin to non-myelinated nerve fibres. The Journal of Physiology. 227: 95-126. PMID 4646588 DOI: 10.1113/jphysiol.1972.sp010022  1
1970 Colquhoun D. How long does a molecule stay on the receptor? Explanation of a paradox. British Journal of Pharmacology. 39: 215P-216P. PMID 5420109  1
1970 Colquhoun D, Tattersall ML. Rapid histamine assays: a method and some theoretical considerations. British Journal of Pharmacology. 38: 241-52. PMID 5413289  1
1968 Colquhoun D. The rate of equilibration in a competitive n drug system and the auto-inhibitory equations of enzyme kinetics: some properties of simple models for passive sensitization. Proceedings of the Royal Society of London. Series B, Biological Sciences. 170: 135-54. PMID 4385241  1
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