Noboru Hiroi - Publications

Affiliations: 
Albert Einstein College of Medicine of Yeshiva University, NY, United States 
Area:
nicotine dependence, autism, mental retardation, schizophrenia

61/200 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hiroi N, Hiramoto T, Sumiyoshi A, Kato R, Yamauchi T, Kang G, Matsumura B, Stevens L, Ryoke R, Nonaka H, Machida A, Nomoto K, Mogi K, Kikusui T, Kawashima R. Structural alterations in the amygdala and impaired social incentive learning in a mouse model of a genetic variant associated with neurodevelopmental disorders. Research Square. PMID 37461714 DOI: 10.21203/rs.3.rs-3070199/v1  0.555
2023 Hiramoto T, Sumiyoshi A, Kato R, Yamauchi T, Kang G, Matsumura B, Stevens LJ, Ryoke R, Nonaka H, Machida A, Nomoto K, Mogi K, Kikusui T, Kawashima R, Hiroi N. Structural alterations in the amygdala and impaired social incentive learning in a mouse model of a genetic variant associated with neurodevelopmental disorders. Biorxiv : the Preprint Server For Biology. PMID 37398198 DOI: 10.1101/2023.06.14.545013  0.555
2021 Hiramoto T, Sumiyoshi A, Yamauchi T, Tanigaki K, Shi Q, Kang G, Ryoke R, Nonaka H, Enomoto S, Izumi T, Bhat MA, Kawashima R, Hiroi N. Tbx1, a gene encoded in 22q11.2 copy number variant, is a link between alterations in fimbria myelination and cognitive speed in mice. Molecular Psychiatry. PMID 34737458 DOI: 10.1038/s41380-021-01318-4  0.525
2021 Nakamura M, Ye K, E Silva MB, Yamauchi T, Hoeppner DJ, Fayyazuddin A, Kang G, Yuda EA, Nagashima M, Enomoto S, Hiramoto T, Sharp R, Kaneko I, Tajinda K, Adachi M, ... ... Hiroi N, et al. Computational identification of variables in neonatal vocalizations predictive for postpubertal social behaviors in a mouse model of 16p11.2 deletion. Molecular Psychiatry. PMID 33859357 DOI: 10.1038/s41380-021-01089-y  0.574
2020 Kato R, Machida A, Nomoto K, Kang G, Hiramoto T, Tanigaki K, Mogi K, Hiroi N, Kikusui T. Maternal approach behaviors toward neonatal calls are impaired by mother's experiences of raising pups with a risk gene variant for autism. Developmental Psychobiology. PMID 32573780 DOI: 10.1002/Dev.22006  0.531
2019 Zinkstok JR, Boot E, Bassett AS, Hiroi N, Butcher NJ, Vingerhoets C, Vorstman JAS, van Amelsvoort TAMJ. Neurobiological perspective of 22q11.2 deletion syndrome. The Lancet. Psychiatry. PMID 31395526 DOI: 10.1016/S2215-0366(19)30076-8  0.341
2019 Hiroi N, Yamauchi T. Modeling and predicting developmental trajectories of neuropsychiatric dimensions associated with copy number variations. The International Journal of Neuropsychopharmacology. PMID 31135887 DOI: 10.1093/Ijnp/Pyz026  0.379
2018 Hiroi N. Critical Reappraisal of Mechanistic Links of Copy Number Variants to Dimensional Constructs of Neuropsychiatric Disorders in Mouse Models. Psychiatry and Clinical Neurosciences. PMID 29369447 DOI: 10.1111/Pcn.12641  0.354
2017 Boku S, Izumi T, Abe S, Takahashi T, Nishi A, Nomaru H, Naka Y, Kang G, Nagashima M, Hishimoto A, Enomoto S, Duran-Torres G, Tanigaki K, Zhang J, Ye K, ... ... Hiroi N, et al. Copy number elevation of 22q11.2 genes arrests the developmental maturation of working memory capacity and adult hippocampal neurogenesis. Molecular Psychiatry. PMID 28827761 DOI: 10.1038/Mp.2017.158  0.351
2017 Solís O, García-Montes JR, Garcia-Sanz P, Herranz AS, Asensio MJ, Kang G, Hiroi N, Moratalla R. Human COMT over-expression confers a heightened susceptibility to dyskinesia in mice. Neurobiology of Disease. PMID 28315782 DOI: 10.1016/J.Nbd.2017.03.006  0.723
2016 Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AF, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA, Carter CS, Cook EH, Daskalakis ZJ, DiLeone RJ, Duman RS, ... ... Hiroi N, et al. Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research. Biological Psychiatry. 80: 84-6. PMID 27346079 DOI: 10.1016/J.Biopsych.2016.05.004  0.708
2016 Hiroi N, Nishi A. Dimensional Deconstruction and Reconstruction of CNV-Associated Neuropsychiatric Disorders Handbook of Behavioral Neuroscience. 23: 285-302. DOI: 10.1016/B978-0-12-800981-9.00017-1  0.328
2015 Takahashi T, Okabe S, Broin PÓ, Nishi A, Ye K, Beckert MV, Izumi T, Machida A, Kang G, Abe S, Pena JL, Golden A, Kikusui T, Hiroi N. Structure and function of neonatal social communication in a genetic mouse model of autism. Molecular Psychiatry. PMID 26666205 DOI: 10.1038/Mp.2015.190  0.315
2014 Hiroi N. Small cracks in the dam: rare genetic variants provide opportunities to delve into mechanisms of neuropsychiatric disorders. Biological Psychiatry. 76: 91-2. PMID 24948383 DOI: 10.1016/J.Biopsych.2014.05.002  0.332
2013 Hiroi N, Takahashi T, Hishimoto A, Izumi T, Boku S, Hiramoto T. Copy number variation at 22q11.2: from rare variants to common mechanisms of developmental neuropsychiatric disorders. Molecular Psychiatry. 18: 1153-65. PMID 23917946 DOI: 10.1038/Mp.2013.92  0.554
2012 Hiroi N, Hiramoto T, Harper KM, Suzuki G, Boku S. Mouse Models of 22q11.2-Associated Autism Spectrum Disorder. Autism-Open Access. 001. PMID 25089229 DOI: 10.4172/2165-7890.S1-001  0.763
2012 Harper KM, Hiramoto T, Tanigaki K, Kang G, Suzuki G, Trimble W, Hiroi N. Alterations of social interaction through genetic and environmental manipulation of the 22q11.2 gene Sept5 in the mouse brain. Human Molecular Genetics. 21: 3489-99. PMID 22589251 DOI: 10.1093/Hmg/Dds180  0.78
2012 Yoshida A, Yamamoto N, Kinoshita M, Hiroi N, Hiramoto T, Kang G, Trimble WS, Tanigaki K, Nakagawa T, Ito J. Localization of septin proteins in the mouse cochlea. Hearing Research. 289: 40-51. PMID 22575789 DOI: 10.1016/J.Heares.2012.04.015  0.526
2012 Lapidus KA, Nwokafor C, Scott D, Baroni TE, Tenenbaum SA, Hiroi N, Singer RH, Czaplinski K. Transgenic expression of ZBP1 in neurons suppresses cocaine-associated conditioning. Learning & Memory (Cold Spring Harbor, N.Y.). 19: 35-42. PMID 22240322 DOI: 10.1101/Lm.024471.111  0.551
2011 Hiramoto T, Kang G, Suzuki G, Satoh Y, Kucherlapati R, Watanabe Y, Hiroi N. Tbx1: identification of a 22q11.2 gene as a risk factor for autism spectrum disorder in a mouse model. Human Molecular Genetics. 20: 4775-85. PMID 21908517 DOI: 10.1093/Hmg/Ddr404  0.748
2011 Scott D, Hiroi N. Deconstructing craving: dissociable cortical control of cue reactivity in nicotine addiction. Biological Psychiatry. 69: 1052-9. PMID 21429478 DOI: 10.1016/J.Biopsych.2011.01.023  0.469
2010 Scott D, Hiroi N. Emergence of dormant conditioned incentive approach by conditioned withdrawal in nicotine addiction. Biological Psychiatry. 68: 726-32. PMID 20598291 DOI: 10.1016/J.Biopsych.2010.05.017  0.493
2010 Agatsuma S, Dang MT, Li Y, Hiroi N. N-methyl-D-aspartic acid receptors on striatal neurons are essential for cocaine cue reactivity in mice. Biological Psychiatry. 67: 778-80. PMID 20149346 DOI: 10.1016/J.Biopsych.2009.12.023  0.702
2009 Suzuki G, Harper KM, Hiramoto T, Funke B, Lee M, Kang G, Buell M, Geyer MA, Kucherlapati R, Morrow B, Männistö PT, Agatsuma S, Hiroi N. Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice. Human Molecular Genetics. 18: 3914-25. PMID 19617637 DOI: 10.1093/Hmg/Ddp334  0.781
2009 Suzuki G, Harper KM, Hiramoto T, Sawamura T, Lee M, Kang G, Tanigaki K, Buell M, Geyer MA, Trimble WS, Agatsuma S, Hiroi N. Sept5 deficiency exerts pleiotropic influence on affective behaviors and cognitive functions in mice. Human Molecular Genetics. 18: 1652-60. PMID 19240081 DOI: 10.1093/Hmg/Ddp086  0.785
2009 Hiroi N, Scott D. Constitutional mechanisms of vulnerability and resilience to nicotine dependence. Molecular Psychiatry. 14: 653-67. PMID 19238150 DOI: 10.1038/Mp.2009.16  0.316
2009 Hiramoto T, Suzuki G, Kang G, Funke B, Watanabe Y, Kucherlapati R, Morrow B, Hiroi N. Tbx1 heterozygosity impairs working memory in mice Neuroscience Research. 65: S121-S122. DOI: 10.1016/J.Neures.2009.09.576  0.679
2007 Zhu H, Lee M, Agatsuma S, Hiroi N. Pleiotropic impact of constitutive fosB inactivation on nicotine-induced behavioral alterations and stress-related traits in mice. Human Molecular Genetics. 16: 820-36. PMID 17468183 DOI: 10.1093/Hmg/Ddm027  0.803
2006 Agatsuma S, Lee M, Zhu H, Chen K, Shih JC, Seif I, Hiroi N. Monoamine oxidase A knockout mice exhibit impaired nicotine preference but normal responses to novel stimuli. Human Molecular Genetics. 15: 2721-31. PMID 16893910 DOI: 10.1093/Hmg/Ddl206  0.791
2005 Hiroi N, Zhu H, Lee M, Funke B, Arai M, Itokawa M, Kucherlapati R, Morrow B, Sawamura T, Agatsuma S. A 200-kb region of human chromosome 22q11.2 confers antipsychotic-responsive behavioral abnormalities in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 19132-7. PMID 16365290 DOI: 10.1073/Pnas.0509635102  0.791
2005 Agatsuma S, Hiroi N. [Chromosome 22q11 and schizophrenia]. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 25: 79-84. PMID 16220657  0.664
2005 Zhu H, Lee M, Guan F, Agatsuma S, Scott D, Fabrizio K, Fienberg AA, Hiroi N. DARPP-32 phosphorylation opposes the behavioral effects of nicotine. Biological Psychiatry. 58: 981-9. PMID 16084497 DOI: 10.1016/J.Biopsych.2005.05.026  0.785
2005 Hiroi N, Agatsuma S. Genetic susceptibility to substance dependence. Molecular Psychiatry. 10: 336-44. PMID 15583701 DOI: 10.1038/Sj.Mp.4001622  0.688
2004 Agatsuma S, Hiroi N. [Genetic basis of drug dependence and comorbid behavioral traits]. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 24: 137-45. PMID 15291243  0.7
2004 Lee M, Chen K, Shih JC, Hiroi N. MAO-B knockout mice exhibit deficient habituation of locomotor activity but normal nicotine intake. Genes, Brain, and Behavior. 3: 216-27. PMID 15248867 DOI: 10.1111/J.1601-1848.2004.00074.X  0.518
2004 Grande C, Zhu H, Martin AB, Lee M, Ortiz O, Hiroi N, Moratalla R. Chronic treatment with atypical neuroleptics induces striosomal FosB/DeltaFosB expression in rats. Biological Psychiatry. 55: 457-63. PMID 15023572 DOI: 10.1016/J.Biopsych.2003.08.008  0.763
2002 Hiroi N, Martín AB, Grande C, Alberti I, Rivera A, Moratalla R. Molecular dissection of dopamine receptor signaling. Journal of Chemical Neuroanatomy. 23: 237-42. PMID 12048106 DOI: 10.1016/S0891-0618(02)00010-8  0.714
2001 Haile CN, Hiroi N, Nestler EJ, Kosten TA. Differential behavioral responses to cocaine are associated with dynamics of mesolimbic dopamine proteins in Lewis and Fischer 344 rats. Synapse (New York, N.Y.). 41: 179-90. PMID 11391778 DOI: 10.1002/Syn.1073  0.486
1999 Atkins JB, Chlan-Fourney J, Nye HE, Hiroi N, Carlezon WA, Nestler EJ. Region-specific induction of deltaFosB by repeated administration of typical versus atypical antipsychotic drugs. Synapse (New York, N.Y.). 33: 118-28. PMID 10400890 DOI: 10.1002/(Sici)1098-2396(199908)33:2<118::Aid-Syn2>3.0.Co;2-L  0.644
1999 Hiroi N, Fienberg AA, Haile CN, Alburges M, Hanson GR, Greengard P, Nestler EJ. Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant mice. The European Journal of Neuroscience. 11: 1114-8. PMID 10103106 DOI: 10.1046/J.1460-9568.1999.00570.X  0.677
1998 Carlezon WA, Thome J, Olson VG, Lane-Ladd SB, Brodkin ES, Hiroi N, Duman RS, Neve RL, Nestler EJ. Regulation of cocaine reward by CREB. Science (New York, N.Y.). 282: 2272-5. PMID 9856954 DOI: 10.1126/Science.282.5397.2272  0.775
1998 Hiroi N, Marek GJ, Brown JR, Ye H, Saudou F, Vaidya VA, Duman RS, Greenberg ME, Nestler EJ. Essential role of the fosB gene in molecular, cellular, and behavioral actions of chronic electroconvulsive seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6952-62. PMID 9712664 DOI: 10.1523/Jneurosci.18-17-06952.1998  0.623
1998 Fienberg AA, Hiroi N, Mermelstein PG, Song W, Snyder GL, Nishi A, Cheramy A, O'Callaghan JP, Miller DB, Cole DG, Corbett R, Haile CN, Cooper DC, Onn SP, Grace AA, et al. DARPP-32: regulator of the efficacy of dopaminergic neurotransmission. Science (New York, N.Y.). 281: 838-42. PMID 9694658 DOI: 10.1126/Science.281.5378.838  0.653
1998 Rocha BA, Scearce-Levie K, Lucas JJ, Hiroi N, Castanon N, Crabbe JC, Nestler EJ, Hen R. Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. Nature. 393: 175-8. PMID 9603521 DOI: 10.1038/30259  0.524
1998 White NM, Hiroi N. Preferential localization of self-stimulation sites in striosomes/patches in the rat striatum. Proceedings of the National Academy of Sciences of the United States of America. 95: 6486-91. PMID 9600993 DOI: 10.1073/Pnas.95.11.6486  0.565
1998 Hiroi N, Nestler EJ. Nuclear memory: gene transcription and behavior. Advances in Pharmacology (San Diego, Calif.). 42: 1037-41. PMID 9328075 DOI: 10.1016/S1054-3589(08)60924-2  0.466
1998 Hiroi N, Marek GJ, Brown JR, Ye H, Saudou F, Vaidya VA, Duman RS, Greenberg ME, Nestler EJ. Essential Role of thefosB Gene in Molecular, Cellular, and Behavioral Actions of Chronic Electroconvulsive Seizures The Journal of Neuroscience. 18: 6952-6962. DOI: 10.1523/JNEUROSCI.18-17-06952.1998  0.525
1997 Hiroi N, Brown JR, Haile CN, Ye H, Greenberg ME, Nestler EJ. FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects. Proceedings of the National Academy of Sciences of the United States of America. 94: 10397-402. PMID 9294222 DOI: 10.1073/Pnas.94.19.10397  0.633
1996 Berhow MT, Hiroi N, Kobierski LA, Hyman SE, Nestler EJ. Influence of cocaine on the JAK-STAT pathway in the mesolimbic dopamine system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 8019-26. PMID 8987828 DOI: 10.1523/Jneurosci.16-24-08019.1996  0.5
1996 Hiroi N, Graybiel AM. Atypical and typical neuroleptic treatments induce distinct programs of transcription factor expression in the striatum. The Journal of Comparative Neurology. 374: 70-83. PMID 8891947 DOI: 10.1002/(Sici)1096-9861(19961007)374:1<70::Aid-Cne5>3.0.Co;2-K  0.544
1996 Berhow MT, Hiroi N, Nestler EJ. Regulation of ERK (extracellular signal regulated kinase), part of the neurotrophin signal transduction cascade, in the rat mesolimbic dopamine system by chronic exposure to morphine or cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 4707-15. PMID 8764658 DOI: 10.1523/Jneurosci.16-15-04707.1996  0.485
1995 Chen J, Nye HE, Kelz MB, Hiroi N, Nakabeppu Y, Hope BT, Nestler EJ. Regulation of delta FosB and FosB-like proteins by electroconvulsive seizure and cocaine treatments. Molecular Pharmacology. 48: 880-9. PMID 7476919  0.621
1994 Xu M, Moratalla R, Gold LH, Hiroi N, Koob GF, Graybiel AM, Tonegawa S. Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses. Cell. 79: 729-42. PMID 7954836 DOI: 10.1016/0092-8674(94)90557-6  0.787
1993 Hiroi N, White NM. The ventral pallidum area is involved in the acquisition but not expression of the amphetamine conditioned place preference. Neuroscience Letters. 156: 9-12. PMID 8414197 DOI: 10.1016/0304-3940(93)90426-L  0.586
1993 White NM, Hiroi N. Amphetamine conditioned cue preference and the neurobiology of drug-seeking Seminars in Neuroscience. 5: 329-336. DOI: 10.1016/S1044-5765(05)80040-5  0.618
1992 White NM, Hiroi N. Pipradrol conditioned place preference is blocked by SCH23390. Pharmacology, Biochemistry, and Behavior. 43: 377-80. PMID 1359572 DOI: 10.1016/0091-3057(92)90165-C  0.595
1991 Hiroi N, White NM. The lateral nucleus of the amygdala mediates expression of the amphetamine-produced conditioned place preference. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 2107-16. PMID 2066777 DOI: 10.1523/Jneurosci.11-07-02107.1991  0.329
1991 Hiroi N, White NM. The amphetamine conditioned place preference: differential involvement of dopamine receptor subtypes and two dopaminergic terminal areas. Brain Research. 552: 141-52. PMID 1833032 DOI: 10.1016/0006-8993(91)90672-I  0.612
1991 White NM, Packard MG, Hiroi N. Place conditioning with dopamine D1 and D2 agonists injected peripherally or into nucleus accumbens. Psychopharmacology. 103: 271-6. PMID 1674160 DOI: 10.1007/Bf02244216  0.711
1990 Hiroi N, White NM. The reserpine-sensitive dopamine pool mediates (+)-amphetamine-conditioned reward in the place preference paradigm. Brain Research. 510: 33-42. PMID 2322845 DOI: 10.1016/0006-8993(90)90724-P  0.602
1989 Hiroi N, White NM. Conditioned stereotypy: behavioral specification of the UCS and pharmacological investigation of the neural change. Pharmacology, Biochemistry, and Behavior. 32: 249-58. PMID 2543991 DOI: 10.1016/0091-3057(89)90241-4  0.623
Low-probability matches (unlikely to be authored by this person)
2015 Boku S, Toda H, Nakagawa S, Kato A, Inoue T, Koyama T, Hiroi N, Kusumi I. Neonatal maternal separation alters the capacity of adult neural precursor cells to differentiate into neurons via methylation of retinoic Acid receptor gene promoter. Biological Psychiatry. 77: 335-44. PMID 25127741 DOI: 10.1016/J.Biopsych.2014.07.008  0.287
2020 Yamauchi T, Kang G, Hiroi N. Heterozygosity of murine Crkl does not recapitulate behavioral dimensions of human 22q11.2 hemizygosity. Genes, Brain, and Behavior. PMID 33269541 DOI: 10.1111/gbb.12719  0.287
2017 Hiroi N, Boku S, Abe S, Izumi T, Takahashi T, Nishi A, Nomaru H, Naka Y, Kang G, Hishimoto A, Tanigaki K, Zhang J, Ye K, Kato S, Männistö P, et al. 32. Copy Number Variation of 22q11.2 Genes Arrests the Developmental Maturation of Working Memory Capacity and Adult Hippocampal Neurogenesis Biological Psychiatry. 81: S14. DOI: 10.1016/J.Biopsych.2017.02.043  0.278
2015 Hishimoto A, Nomaru H, Ye K, Nishi A, Lim J, Aguilan JT, Nieves E, Kang G, Angeletti RH, Hiroi N. Molecular Histochemistry Identifies Peptidomic Organization and Reorganization Along Striatal Projection Units. Biological Psychiatry. PMID 26520239 DOI: 10.1016/J.Biopsych.2015.09.012  0.275
2018 Ó Broin P, Beckert MV, Takahashi T, Izumi T, Ye K, Kang G, Pouso P, Topolski M, Pena JL, Hiroi N. Computational Analysis of Neonatal Mouse Ultrasonic Vocalization. Current Protocols in Mouse Biology. 8: e46. PMID 29927553 DOI: 10.1002/Cpmo.46  0.272
2002 Yoshida-Hiroi M, Bradbury MJ, Eisenhofer G, Hiroi N, Vale WW, Novotny GE, Hartwig HG, Scherbaum WA, Bornstein SR. Chromaffin cell function and structure is impaired in corticotropin-releasing hormone receptor type 1-null mice. Molecular Psychiatry. 7: 967-74. PMID 12399950 DOI: 10.1038/sj.mp.4001143  0.26
1995 Hiroi N. Compartmental organization of calretinin in the rat striatum. Neuroscience Letters. 197: 223-6. PMID 8552304 DOI: 10.1016/0304-3940(95)11942-P  0.254
2023 Makinodan M, Komori T, Okamura K, Ikehara M, Yamamuro K, Endo N, Okumura K, Yamauchi T, Ikawa D, Ouji-Sageshima N, Toritsuka M, Takada R, Kayashima Y, Ishida R, Mori Y, ... ... Hiroi N, et al. Brain-derived neurotrophic factor from microglia regulates neuronal development in the medial prefrontal cortex and its associated social behavior. Research Square. PMID 37461488 DOI: 10.21203/rs.3.rs-3094335/v1  0.249
2024 Komori T, Okamura K, Ikehara M, Yamamuro K, Endo N, Okumura K, Yamauchi T, Ikawa D, Ouji-Sageshima N, Toritsuka M, Takada R, Kayashima Y, Ishida R, Mori Y, Kamikawa K, ... ... Hiroi N, et al. Brain-derived neurotrophic factor from microglia regulates neuronal development in the medial prefrontal cortex and its associated social behavior. Molecular Psychiatry. PMID 38243072 DOI: 10.1038/s41380-024-02413-y  0.245
2017 Esposito G, Hiroi N, Scattoni ML. Cry, baby, cry: Expression of Distress as a Biomarker and Modulator in Autism Spectrum Disorder. The International Journal of Neuropsychopharmacology. PMID 28204487 DOI: 10.1093/Ijnp/Pyx014  0.235
2000 Bornstein SR, Tian H, Haidan A, Böttner A, Hiroi N, Eisenhofer G, McCann SM, Chrousos GP, Roffler-Tarlov S. Deletion of tyrosine hydroxylase gene reveals functional interdependence of adrenocortical and chromaffin cell system in vivo. Proceedings of the National Academy of Sciences of the United States of America. 97: 14742-7. PMID 11121073 DOI: 10.1073/pnas.97.26.14742  0.231
2017 Kikusui T, Hiroi N. A Self-Generated Environmental Factor as a Potential Contributor to Atypical Early Social Communication in Autism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 42: 378. PMID 27909329 DOI: 10.1038/Npp.2016.225  0.227
2002 Yoshida-Hiroi M, Bradbury MJ, Eisenhofer G, Hiroi N, Vale WW, Novotny GE, Hartwig HG, Scherbaum WA, Bornstein SR. Adrenal medulla in CRHR type 1-deficient mice Molecular Psychiatry. 7: 819. DOI: 10.1038/sj.mp.4001184  0.208
2003 Hiroi N, Kino T, Bassett M, Rainey WE, Phung M, Abu-Asab M, Fojo T, Briata P, Chrousos GP, Bornstein SR. Pituitary homeobox factor 1, a novel transcription factor in the adrenal regulating steroid 11beta-hydroxylase. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 35: 273-8. PMID 12915995 DOI: 10.1055/s-2003-41301  0.137
2002 Galon J, Franchimont D, Hiroi N, Frey G, Boettner A, Ehrhart-Bornstein M, O'Shea JJ, Chrousos GP, Bornstein SR. Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 61-71. PMID 11772937 DOI: 10.1096/fj.01-0245com  0.136
2001 Maurer M, Trajanoski Z, Frey G, Hiroi N, Galon J, Willenberg HS, Gold PW, Chrousos GP, Scherbaum WA, Bornstein SR. Differential gene expression profile of glucocorticoids, testosterone, and dehydroepiandrosterone in human cells. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 33: 691-5. PMID 11753752 DOI: 10.1055/S-2001-19142  0.132
2000 Willenberg HS, Bornstein SR, Hiroi N, Päth G, Goretzki PE, Scherbaum WA, Chrousos GP. Effects of a novel corticotropin-releasing-hormone receptor type I antagonist on human adrenal function. Molecular Psychiatry. 5: 137-41. PMID 10822340  0.126
2022 Mai L, Inada H, Kimura R, Kanno K, Matsuda T, Tachibana RO, Tucci V, Komaki F, Hiroi N, Osumi N. Advanced paternal age diversifies individual trajectories of vocalization patterns in neonatal mice. Iscience. 25: 104834. PMID 36039363 DOI: 10.1016/j.isci.2022.104834  0.124
2005 Yoshida-Hiroi M, Tsuchida Y, Yoshino G, Hiroi N. Intranasal administration of ACTH(1-24) stimulates catecholamine secretion. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 37: 489-93. PMID 16138261 DOI: 10.1055/s-2005-870307  0.121
2002 Zouboulis CC, Seltmann H, Hiroi N, Chen W, Young M, Oeff M, Scherbaum WA, Orfanos CE, McCann SM, Bornstein SR. Corticotropin-releasing hormone: an autocrine hormone that promotes lipogenesis in human sebocytes. Proceedings of the National Academy of Sciences of the United States of America. 99: 7148-53. PMID 12011471 DOI: 10.1073/pnas.102180999  0.117
2014 Hiroi N, Swat M, Funahashi A. Assessing uncertainty in model parameters based on sparse and noisy experimental data. Frontiers in Physiology. 5: 128. PMID 24772089 DOI: 10.3389/fphys.2014.00128  0.112
2002 Hiroi N, Ito T, Yamamoto H, Ochiya T, Jinno S, Okayama H. Mammalian Rcd1 is a novel transcriptional cofactor that mediates retinoic acid-induced cell differentiation. The Embo Journal. 21: 5235-44. PMID 12356739 DOI: 10.1093/emboj/cdf521  0.108
2002 Hiroi N, Ichijo T, Ueshiba H, Miyachi Y. Intranasal administration of adrenocorticotropin-(1-24) stimulates adrenocortical hormone secretion. The Journal of Clinical Endocrinology and Metabolism. 87: 1750-3. PMID 11932311 DOI: 10.1210/jcem.87.4.8399  0.103
1998 Hiroi N, Yakushiji F, Shimojo M, Watanabe S, Sugano S, Yamaguchi N, Miyachi Y. Human ACTH hypersensitivity syndrome associated with abnormalities of the ACTH receptor gene. Clinical Endocrinology. 48: 129-34. PMID 9579221 DOI: 10.1046/j.1365-2265.1998.00397.x  0.1
2012 Sue M, Akama T, Kawashima A, Nakamura H, Hara T, Tanigawa K, Wu H, Yoshihara A, Ishido Y, Hiroi N, Yoshino G, Kohn LD, Ishii N, Suzuki K. Propylthiouracil increases sodium/iodide symporter gene expression and iodide uptake in rat thyroid cells in the absence of TSH. Thyroid : Official Journal of the American Thyroid Association. 22: 844-52. PMID 22853729 DOI: 10.1089/Thy.2011.0290  0.098
2011 Hiroi N, Lu J, Iba K, Tabira A, Yamashita S, Okada Y, Flamm C, Oka K, Köhler G, Funahashi A. Physiological environment induces quick response - slow exhaustion reactions. Frontiers in Physiology. 2: 50. PMID 21960972 DOI: 10.3389/Fphys.2011.00050  0.094
2020 Marttinen M, Ferreira CB, Paldanius KMA, Takalo M, Natunen T, Mäkinen P, Leppänen L, Leinonen V, Tanigaki K, Kang G, Hiroi N, Soininen H, Rilla K, Haapasalo A, Hiltunen M. Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ. Cells. 9. PMID 33203136 DOI: 10.3390/cells9112482  0.093
2002 Mirani M, Elenkov I, Volpi S, Hiroi N, Chrousos GP, Kino T. HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 169: 6361-8. PMID 12444143  0.091
2009 Hiroi N, Yoshihara A, Sue M, Ichijo T, Iga R, Shigemitsu R, Masai N, Yoshino G. Hyponatremia following administration of losartan, an angiotensin II receptor blocker, in a patient with isolated ACTH deficiency American Journal of Case Reports. 10: 141-144.  0.088
2006 Nagasawa K, Yamamoto N, Hiroi N, Yoshino G. Dehydroepiandrosterone reduces intracellular lipid content, peroxysome proliferator activated receptor-γ mRNA and mRNAs of the genes related to lipid transport and metabolism in mature 3T3-L1 adipocytes Journal of the Medical Society of Toho University. 53: 21-30.  0.087
1995 Shimojo M, Hiroi N, Yakushiji F, Ueshiba H, Yamaguchi N, Miyachi Y. Differences in down-regulation of glucocorticoid receptor mRNA by cortisol, prednisolone and dexamethasone in HeLa cells. Endocrine Journal. 42: 629-36. PMID 8574285  0.083
2001 Hiroi N, Chrousos GP, Kohn B, Lafferty A, Abu-Asab M, Bonat S, White A, Bornstein SR. Adrenocortical-pituitary hybrid tumor causing Cushing's syndrome. The Journal of Clinical Endocrinology and Metabolism. 86: 2631-7. PMID 11397864 DOI: 10.1210/jcem.86.6.7590  0.082
2002 Wolkersdörfer GW, Bornstein SR, Higginbotham JN, Hiroi N, Vaquero JJ, Green MV, Blaese RM, Aguilera G, Chrousos GP, Ramsey WJ. A novel approach using transcomplementing adenoviral vectors for gene therapy of adrenocortical cancer. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 34: 279-87. PMID 12173067 DOI: 10.1055/s-2002-33255  0.081
2012 Yoshihara A, Hara T, Kawashima A, Akama T, Tanigawa K, Wu H, Sue M, Ishido Y, Hiroi N, Ishii N, Yoshino G, Suzuki K. Regulation of dual oxidase expression and H2O2 production by thyroglobulin. Thyroid : Official Journal of the American Thyroid Association. 22: 1054-62. PMID 22874065 DOI: 10.1089/thy.2012.0003  0.075
2007 Isobe K, Muraoka S, Sugino K, Yamazaki Y, Kikuchi N, Hamanaka N, Takai Y, Shimizu K, Kimura K, Hiroi N, Shibuya K, Homma S. [Case of pulmonary aspergillosis associated with inappropriate antidiuretic hormone syndrome caused by voriconazole therapy]. Nihon Kokyå«Ki Gakkai Zasshi = the Journal of the Japanese Respiratory Society. 45: 489-93. PMID 17644946  0.074
2006 Yamamoto N, Imai J, Watanabe M, Hiroi N, Sugano S, Yoshino G. Restoration of transforming growth factor-beta type II receptor reduces tumorigenicity in the human adrenocortical carcinoma SW-13 cell line. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 38: 159-66. PMID 16673206 DOI: 10.1055/s-2006-925185  0.074
1997 Hiroi N, Miyachi Y. [ACTH receptor]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 55: 476-9. PMID 9172570  0.073
2013 Hiroi N, Iba K, Tabira A, Okuhara T, Kubojima T, Hiraiwa T, Kobayashi TJ, Oka K, Funahashi A. In vivo oriented modeling with consideration of intracellular crowding. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2013: 2716-9. PMID 24110288 DOI: 10.1109/EMBC.2013.6610101  0.073
2001 Hiroi N, Wong ML, Licinio J, Park C, Young M, Gold PW, Chrousos GP, Bornstein SR. Expression of corticotropin releasing hormone receptors type I and type II mRNA in suicide victims and controls. Molecular Psychiatry. 6: 540-6. PMID 11526468 DOI: 10.1038/Sj.Mp.4000908  0.073
2015 Tamura N, Simon JE, Nayak A, Shenoy R, Hiroi N, Boilot V, Funahashi A, Draviam VM. A proteomic study of mitotic phase-specific interactors of EB1 reveals a role for SXIP-mediated protein interactions in anaphase onset. Biology Open. 4: 155-69. PMID 25596275 DOI: 10.1242/bio.201410413  0.071
2001 Ishikawa M, Hiroi N, Kamioka T, Tanaka T, Tachibana T, Ishikawa H, Miyachi Y. Metabolic effects of 20 kDa and 22 kDa human growth hormones on adult male spontaneous dwarf rats. European Journal of Endocrinology / European Federation of Endocrine Societies. 145: 791-7. PMID 11720906  0.071
2006 Oeff MK, Seltmann H, Hiroi N, Nastos A, Makrantonaki E, Bornstein SR, Zouboulis CC. Differential regulation of Toll-like receptor and CD14 pathways by retinoids and corticosteroids in human sebocytes. Dermatology (Basel, Switzerland). 213: 266. PMID 17033190 DOI: 10.1159/000095056  0.069
1998 Miyachi Y, Ogome C, Matsumoto M, Hiroi N, Yakushiji F. [Abnormal sex development and impotence]. Nihon Naika Gakkai Zasshi. the Journal of the Japanese Society of Internal Medicine. 87: 1040-6. PMID 9702015  0.069
2006 Hiroi N, Funahashi A, Kitano H. Comparative studies of suppression of malignant cancer cell phenotype by antisense oligo DNA and small interfering RNA. Cancer Gene Therapy. 13: 7-12. PMID 16082382 DOI: 10.1038/Sj.Cgt.7700869  0.068
2012 Yoshihara A, Hara T, Kawashima A, Akama T, Tanigawa K, Wu H, Sue M, Ishido Y, Hiroi N, Ishii N, Yoshino G, Suzuki K. Regulation of dual oxidase (DUOX) expression and H2O2 production by thyroglobulin. Thyroid : Official Journal of the American Thyroid Association. PMID 22612456 DOI: 10.1089/thy.2012-0003  0.067
2004 Hiroi N, Ichijo T, Tsuchida Y, Miyachi Y. A trial of intranasal ACTH(1-24) administration to a patient with isolated ACTH deficiency. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 10: CS9-13. PMID 14737049  0.066
2011 Yoshida-Hiroi M, Koizumi M, Oka R, Mitsuda A, Hiroi N. First case report of acquired pure red cell aplasia associated with micafungin. Internal Medicine (Tokyo, Japan). 50: 1051-4. PMID 21532231 DOI: JST.JSTAGE/internalmedicine/50.4303  0.066
2014 Luo Y, Hara T, Ishido Y, Yoshihara A, Oda K, Makino M, Ishii N, Hiroi N, Suzuki K. Rapid preparation of high-purity nuclear proteins from a small number of cultured cells for use in electrophoretic mobility shift assays. Bmc Immunology. 15: 586. PMID 25527077 DOI: 10.1186/s12865-014-0062-z  0.064
2012 Takizawa H, Hiroi N, Funahashi A. Mathematical modeling of sustainable synaptogenesis by repetitive stimuli suggests signaling mechanisms in vivo. Plos One. 7: e51000. PMID 23284653 DOI: 10.1371/journal.pone.0051000  0.063
2013 Sue M, Yoshihara A, Kuboki K, Hiroi N, Yoshino G. A case of severe acute necrotizing pancreatitis after administration of sitagliptin. Clinical Medicine Insights. Case Reports. 6: 23-7. PMID 23467428 DOI: 10.4137/CCRep.S10856  0.059
2003 Vrezas I, Willenberg HS, Mansmann G, Hiroi N, Fritzen R, Bornstein SR. Ectopic adrenocorticotropin (ACTH) and corticotropin-releasing hormone (CRH) production in the adrenal gland: basic and clinical aspects. Microscopy Research and Technique. 61: 308-14. PMID 12768546 DOI: 10.1002/jemt.10340  0.059
2005 Hiroi N, Ishimori H, Kaneko Y, Kiguchi H, Nakamura T, Higa M. Bilateral adrenal hemorrhage due to sepsis resulting in acute adrenal crisis. Internal Medicine (Tokyo, Japan). 44: 1017-8. PMID 16258227 DOI: JST.JSTAGE/internalmedicine/44.1017  0.058
1997 Miyachi Y, Hiroi N, Matsumoto M. [Receptor diseases and their evaluation methods]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 55: 435-43. PMID 9172563  0.057
2010 Hiroi N, Yoshihara A, Sue M, Yoshino G, Higa M. Central adrenal insufficiency and diabetes insipidus misdiagnosed as severe depression. Clinical Medicine Insights. Case Reports. 3: 55-8. PMID 21769255  0.056
2012 Hiroi N, Okuhara T, Kubojima T, Iba K, Tabira A, Yamashita S, Okada Y, Kobayashi TJ, Funahashi A. Physiological Intracellular Crowdedness is Defined by the Perimeter-to-Area Ratio of Sub-Cellular Compartments. Frontiers in Physiology. 3: 293. PMID 22936917 DOI: 10.3389/fphys.2012.00293  0.056
2007 Hiroi N, Funahashi A. Kinetics of dimension-restricted conditions Introduction to Systems Biology. 261-281. DOI: 10.1007/978-1-59745-531-2_14  0.055
2007 Hiroi N, Sakamoto Y, Urita Y, Higa M, Kuboki K, Yoshino G. Graves' disease with intractable diarrhea, chylous ascites, and chylothorax: a case report. Thyroid : Official Journal of the American Thyroid Association. 17: 1299-303. PMID 18047423 DOI: 10.1089/thy.2007.0006  0.055
2007 Nordling TE, Hiroi N, Funahashi A, Kitano H. Deduction of intracellular sub-systems from a topological description of the network. Molecular Biosystems. 3: 523-9. PMID 17639126 DOI: 10.1039/B702142A  0.052
2013 Corrigan AM, Shrestha RL, Zulkipli I, Hiroi N, Liu Y, Tamura N, Yang B, Patel J, Funahashi A, Donald A, Draviam VM. Automated tracking of mitotic spindle pole positions shows that LGN is required for spindle rotation but not orientation maintenance. Cell Cycle (Georgetown, Tex.). 12: 2643-55. PMID 23907121 DOI: 10.4161/Cc.25671  0.047
2015 Nakai Y, Ozeki M, Hiraiwa T, Tanimoto R, Funahashi A, Hiroi N, Taniguchi A, Nonaka S, Boilot V, Shrestha R, Clark J, Tamura N, Draviam VM, Oku H. High-speed microscopy with an electrically tunable lens to image the dynamics of in vivo molecular complexes. The Review of Scientific Instruments. 86: 013707. PMID 25638090 DOI: 10.1063/1.4905330  0.045
2003 Friedberg M, Zoumakis E, Hiroi N, Bader T, Chrousos GP, Hochberg Z. Modulation of 11 beta-hydroxysteroid dehydrogenase type 1 in mature human subcutaneous adipocytes by hypothalamic messengers. The Journal of Clinical Endocrinology and Metabolism. 88: 385-93. PMID 12519881 DOI: 10.1210/jc.2002-020510  0.045
2013 Keller R, Dörr A, Tabira A, Funahashi A, Ziller MJ, Adams R, Rodriguez N, Le Novère N, Hiroi N, Planatscher H, Zell A, Dräger A. The systems biology simulation core algorithm. Bmc Systems Biology. 7: 55. PMID 23826941 DOI: 10.1186/1752-0509-7-55  0.044
1995 Yakushiji F, Kita M, Hiroi N, Ueshiba H, Monma I, Miyachi Y. Exacerbation of rheumatoid arthritis after removal of adrenal adenoma in Cushing's syndrome. Endocrine Journal. 42: 219-23. PMID 7627266  0.043
2005 Kaneko Y, Higa M, Hiroi N, Yamamuro W, Yoshino G. Acute effect of nateglinide on insulin secretion after meal tolerance test Journal of the Medical Society of Toho University. 52: 141-147.  0.04
2002 Bader T, Zoumakis E, Friedberg M, Hiroi N, Chrousos GP, Hochberg Z. Human adipose tissue under in vitro inhibition of 11beta-hydroxysteroid dehydrogenase type 1: differentiation and metabolism changes. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 34: 752-7. PMID 12660894 DOI: 10.1055/s-2002-38255  0.038
2015 Sumiyoshi K, Hirata K, Hiroi N, Funahashi A. Acceleration of discrete stochastic biochemical simulation using GPGPU. Frontiers in Physiology. 6: 42. PMID 25762936 DOI: 10.3389/fphys.2015.00042  0.038
2011 Akishima-Fukasawa Y, Yoshihara A, Ishikawa Y, Watanabe N, Hiroi N, Akasaka Y, Sasano H, Ishii T, Yoshino G. Malignant adrenal rest tumor of the retroperitoneum producing adrenocortical steroids. Endocrine Pathology. 22: 112-7. PMID 21374072 DOI: 10.1007/s12022-011-9152-0  0.038
2001 Hiroi N, Ichijo T, Shimojo M, Ueshiba H, Tsuboi K, Miyachi Y. Pituitary apoplexy caused by luteinizing hormone-releasing hormone in prolactin-producing adenoma. Internal Medicine (Tokyo, Japan). 40: 747-50. PMID 11518116  0.036
2010 Sue M, Yoshihara A, Okubo Y, Ishikawa M, Ando Y, Hiroi N, Shibuya K, Yoshino G. A case of juvenile acromegaly that was initially diagnosed as severe congestive heart failure from acromegaly-induced dilated cardiomyopathy. Internal Medicine (Tokyo, Japan). 49: 2117-21. PMID 20930439 DOI: JST.JSTAGE/internalmedicine/49.3972  0.035
2014 Luo Y, Kawashima A, Ishido Y, Yoshihara A, Oda K, Hiroi N, Ito T, Ishii N, Suzuki K. Iodine excess as an environmental risk factor for autoimmune thyroid disease. International Journal of Molecular Sciences. 15: 12895-912. PMID 25050783 DOI: 10.3390/ijms150712895  0.033
2010 Ishikawa M, Kuboki K, Okubo Y, Shigemitsu R, Iga R, Masai N, Miyagi M, Ando Y, Iso K, Hiroi N, Ueshiba H, Sugo N, Shibuya K, Yoshino G. A case of hypoglycemia due to growth hormone deficiency in a patient receiving glimepiride Journal of the Medical Society of Toho University. 57: 274-280.  0.031
2002 Ueshiba H, Shimizu Y, Hiroi N, Yakushiji F, Shimojo M, Tsuboi K, Miyachi Y. Decreased steroidogenic enzyme 17,20-lyase and increased 17-hydroxylase activities in type 2 diabetes mellitus. European Journal of Endocrinology / European Federation of Endocrine Societies. 146: 375-80. PMID 11888844  0.031
2006 Hiroi N, Yanagisawa R, Yoshida-Hiroi M, Endo T, Kawase T, Tsuchida Y, Toyama K, Shibuya K, Nakata K, Yoshino G. Retroperitoneal hemorrhage due to bilateral adrenal metastases from lung adenocarcinoma. Journal of Endocrinological Investigation. 29: 551-4. PMID 16840834  0.03
2013 Takanashi N, Sato Y, Ohta M, Hiroi N, Okumura F, Yamada A. Human-computer interaction technology using image projection and gesture-based input Nec Technical Journal. 7: 122-126.  0.03
2011 Oka R, Hiroi N, Shigemitsu R, Sue M, Oshima Y, Yoshida-Hiroi M. Type 1 Diabetes Mellitus Associated with Pegylated Interferon-α Plus Ribavirin Treatment for Chronic Hepatitis C: Case Report and Literature Review. Clinical Medicine Insights. Endocrinology and Diabetes. 4: 39-45. PMID 22879793 DOI: 10.4137/CMED.S7815  0.03
2007 Hiroi N, Ichijo T, Tsuchida Y, Yoshino G. Turner syndrome with gonadal dysgenesis and tall stature: A case report Endocrinologist. 17: 172-174. DOI: 10.1097/TEN.0b013e31806b9522  0.03
2008 Sue M, Yoshihara A, Otani T, Tsuchida Y, Higa M, Hiroi N. Characteristics of fulminant type 1 diabetes mellitus. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 14: CS97-101. PMID 18830199  0.03
2011 Osada E, Hiroi N, Sue M, Masai N, Iga R, Shigemitsu R, Oka R, Miyagi M, Iso K, Kuboki K, Yoshino G. Thyroid storm associated with Graves' disease covered by diabetic ketoacidosis: A case report. Thyroid Research. 4: 8. PMID 21492449 DOI: 10.1186/1756-6614-4-8  0.029
1999 Hiroi N, Maruta H, Tanuma S. Fas-mediated apoptosis in Jurkat cells is suppressed in the pre-G2/M phase. Apoptosis : An International Journal On Programmed Cell Death. 4: 255-61. PMID 14634276 DOI: 10.1023/A:1009652825846  0.029
2013 Takizawa H, Nakamura K, Tabira A, Chikahara Y, Matsui T, Hiroi N, Funahashi A. LibSBMLSim: a reference implementation of fully functional SBML simulator. Bioinformatics (Oxford, England). 29: 1474-6. PMID 23564843 DOI: 10.1093/bioinformatics/btt157  0.028
2009 Yamada H, Osana Y, Ishimori T, Ooya T, Yoshimi M, Nishikawa Y, Funahashi A, Hiroi N, Amano H, Shibata Y, Oguri K. A modular approach to heterogeneous biochemical model simulation on an FPGA Reconfig'09 - 2009 International Conference On Reconfigurable Computing and Fpgas. 125-130. DOI: 10.1109/ReConFig.2009.55  0.024
2010 Yamada H, Ogawa Y, Ooya T, Ishimori T, Osana Y, Yoshimi M, Nishikawa Y, Funahashi A, Hiroi N, Amano H, Shibata Y, Oguri K. Automatic pipeline construction focused on similarity of rate law functions for an FPGA-based biochemical simulator Ipsj Transactions On System Lsi Design Methodology. 3: 244-256. DOI: 10.2197/ipsjtsldm.3.244  0.023
2011 Sugino I, Hiroi N, Yoshihara A, Sue M, Tojo Y, Iso K, Kuboki K, Tanioka D, Abe T, Yoshino G. Diabetic ketoacidosis associated with adrenocorticotropic hormone-producing pituitary adenoma American Journal of Case Reports. 12: 31-34.  0.023
2006 Sonobe T, Hiroi N, Takenaka M, Nakano Y, Fujita H. Plastic-type OPLEAF as high density fiber array for minimized lateral device spacing optical ICs Ieee/Leos International Conference On Optical Mems and Their Applications Conference, 2006. 124-125.  0.022
2007 Yamada H, Iwanaga N, Shibata Y, Osana Y, Yoshimi M, Iwaoka Y, Nishikawa Y, Kojima T, Amano H, Funahashi A, Hiroi N, Hiroaki Kitano, Kiyoshi Oguri. A combining technique of rate law functions for a cost-effective reconfigurable biological simulator Proceedings - 2007 International Conference On Field Programmable Logic and Applications, Fpl. 808-811. DOI: 10.1109/FPL.2007.4380774  0.021
2009 Sue M, Yoshihara A, Matsui T, Nakajima S, Ikehara T, Watanabe N, Miyagi M, Tojo Y, Kuboki K, Hiroi N, Shibuya K, Yoshino G. A case of ectopic ACTH syndrome due to a malignant pancreatic neuroendocrine tumor Journal of the Medical Society of Toho University. 56: 129-135.  0.021
2005 Iwanagra N, Shibata Y, Yoshimi M, Osana Y, Iwaoka Y, Fukushima T, Amano H, Funahashi A, Hiroi N, Kitano H, Oguri K. Efficient scheduling of rate law functions for ODE-based multimodel biochemical simulation on an FPGA Proceedings - 2005 International Conference On Field Programmable Logic and Applications, Fpl. 2005: 666-669. DOI: 10.1109/FPL.2005.1515809  0.02
2002 Tabeta I, Ueshiba H, Ichijo T, Hiroi N, Yakushiji F, Simojo M, Tsuboi K, Miyachi Y. Comment: the corticotropin-releasing hormone stimulation test in white coat hypertension. The Journal of Clinical Endocrinology and Metabolism. 87: 3672-5. PMID 12161494 DOI: 10.1210/jcem.87.8.8704  0.019
2011 Hiroi N, Sue M, Yoshihara A, Oka R, Shigemitsu R, Higa M, Yoshino G. Effects of valsartan and hydrochlorothiazide in essential hypertensive patients with type 2 diabetes mellitus Therapeutic Research. 32: 107-113.  0.018
2012 Yamashita K, Kobayashi Y, Yoshida E, Yoshifuji A, Ichijo T, Hiroi N, Ouchi H, Higa M. A case of type 1 diabetes diagnosed 17 months after soft-drink ketosis onset Journal of the Japan Diabetes Society. 55: 621-626.  0.017
2012 Hiroi N, Klann M, Iba K, Heras Ciechomski PD, Yamashita S, Tabira A, Okuhara T, Kubojima T, Okada Y, Oka K, Mange R, Unger M, Funahashi A, Koeppl H. From microscopy data to in silico environments for in vivo-oriented simulations Eurasip Journal On Bioinformatics and Systems Biology. 2012. DOI: 10.1186/1687-4153-2012-7  0.016
2010 Hiroi N, Sue M, Yoshihara A, Ichijo T, Yoshida-Hiroi M, Higa M, Yoshino G. Prevalence of adrenal masses in Japanese patients with type 2 diabetes mellitus. Diabetology & Metabolic Syndrome. 2: 71. PMID 21171971 DOI: 10.1186/1758-5996-2-71  0.016
2009 Ishimori T, Yamada H, Shibata Y, Osana Y, Yoshimi M, Nishikawa Y, Amano H, Funahashi A, Hiroi N, Oguri K. Pipeline scheduling with input port constraints for an FPGA-based biochemical simulator Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5453: 368-373. DOI: 10.1007/978-3-642-00641-8_43  0.016
2009 Hiroi N, Yoshihara A, Sue M, Miyagi M, Usui S, Watanabe N, Ichijo T, Tsuchida Y, Kuboki K, Shiraga N, Yoshino G. Diagnosis and treatment of primary aldosteronism: An analysis of 18 cases Journal of the Medical Society of Toho University. 56: 88-96.  0.015
2006 Higa M, Mogami K, Hiroi N. Type 2 diabetes complicated by tuberculous peritonitis. Case report Journal of the Japan Diabetes Society. 49: 209-213.  0.013
2006 Yoshimi M, Osana Y, Iwaoka Y, Nishikawa Y, Kojima T, Shibata Y, Iwanaga N, Funahashi A, Hiroi N, Kitano H, Amano H. An FPGA implementation of high throughput stochastic simulator for large-scale biochemical systems Proceedings - 2006 International Conference On Field Programmable Logic and Applications, Fpl. 227-232. DOI: 10.1109/FPL.2006.311218  0.013
2007 Osana Y, Yoshimi M, Iwaoka Y, Kojima T, Nishikawa Y, Funahashi A, Hiroi N, Shibata Y, Iwanaga N, Kitano H, Amano H. ReCSiP: An FPGA-based general-purpose biochemical simulator Electronics and Communications in Japan, Part Ii: Electronics (English Translation of Denshi Tsushin Gakkai Ronbunshi). 90: 1-10. DOI: 10.1002/Ecjb.20370  0.012
2010 Tajima F, Nishiyama Y, Hiroi N, Hashimoto Y. Standard optical coaxial double fiber diameter and refractive index measurement, accuracy, and precision using light scattering at normal incidence. Journal of the Optical Society of America. a, Optics, Image Science, and Vision. 27: 1-5. PMID 20035296 DOI: 10.1364/JOSAA.27.000001  0.012
2008 Ishikawa Y, Miyagi M, Matsumoto T, Watanabe N, Tojo Y, Hiroi N, Kuboki K, Yoshino G, Tsubota T, Yoshihara K. [Beriberi heart failure caused by a retort pouch diet menu]. Nihon Naika Gakkai Zasshi. the Journal of the Japanese Society of Internal Medicine. 97: 2552-4. PMID 19051749  0.012
2007 Yoshimi M, Iwaoka Y, Nishikawa Y, Kojima T, Osana Y, Funahashi A, Hiroi N, Shibata Y, Iwanaga N, Yamada H, Kitano H, Amano H. FPGA implementation of a data-driven stochastic biochemical simulator with the next reaction method Proceedings - 2007 International Conference On Field Programmable Logic and Applications, Fpl. 254-259. DOI: 10.1109/FPL.2007.4380656  0.011
2006 Terai H, Hiroi N, Kaneko Y, Higa M. A case of alcoholic ketoacidosis with type 2 diabetes mellitus Journal of the Japan Diabetes Society. 49: 343-348.  0.011
2009 Ooya T, Yamada H, Ishimori T, Shibata Y, Osana Y, Oguri K, Yoshimi M, Nishikawa Y, Funahashi A, Hiroi N, Amano H. Configuring area and performance: Empirical evaluation on an FPGA-based biochemical simulator Fpl 09: 19th International Conference On Field Programmable Logic and Applications. 679-682. DOI: 10.1109/FPL.2009.5272335  0.011
2009 Yoshihara A, Sue M, Hiroi N, Kawamura T, Aikawa A, Yoshino G. Urinary calculus after kidney transplantation with persistent secondary hyperparathyroidism. Internal Medicine (Tokyo, Japan). 48: 577-8. PMID 19336964 DOI: JST.JSTAGE/internalmedicine/48.1976  0.01
2006 Sonobe T, Hiroi N, Takenaka M, Nakano Y, Fujita H. OPLEAF fiber array for high density optical IC Ieej Transactions On Sensors and Micromachines. 126: 255-260+7.  0.01
2010 Hiroi N, Masai N, Iga R, Ishii J, Yoshihara A, Sue M, Tsuchiya M, Shiraga N, Shibuya K, Kaneko H, Yoshino G. Localization of insulinoma by arterial stimulation and venous sampling (ASVS) and intraoperative ultrasonography American Journal of Case Reports. 11: 150-154.  0.01
2016 Funahashi A, Hiroi N. Simulation technology and its application in systems biology Folia Pharmacologica Japonica. 147: 101-106. DOI: 10.1254/fpj.147.101  0.01
2014 Hiraiwa T, Kimura T, Takenaka Y, Tanamoto R, Ota H, Kimura H, Taguchi Y, Miki N, Matsumoto Y, Oka K, Funahashi A, Hiroi N. Fabrication method to a high resolution control in the space of cell culturing environment with microfluidic system Proceedings of the Ieee International Conference On Micro Electro Mechanical Systems (Mems). 264-267. DOI: 10.1109/MEMSYS.2014.6765626  0.01
2012 Draviam VM, Funahashi A, Hiroi N, Kimura A, Kobayashi TJ. Meeting report of the International Workshop on Quantitative Biology 2012: mesoscopic and microscopic worlds meet. Frontiers in Physiology. 3: 479. PMID 23335898 DOI: 10.3389/fphys.2012.00479  0.01
2012 Narabayashi Y, Ishikawa M, Sakamoto K, Morise A, Hiroi N, Kuboki K, Yoshino G, Shiba T. A case of fasting hypoglycemia in diabetes mellitus associated with growth hormone denciency Journal of the Japan Diabetes Society. 55: 110-115.  0.01
2012 Higa M, Yoshida E, Yoshifuji A, Iga R, Yamashita K, Hongo M, Ichijo T, Ouchi H, Hiroi N. Mitochondrial diabetes accompanied by benign symmetric lipomatosis - A case report Journal of the Japan Diabetes Society. 55: 17-22.  0.01
2010 Ogawa Y, Ooya T, Osana Y, Yoshimi M, Nishikawa Y, Funahashi A, Hiroi N, Amano H, Shibata Y, Oguri K. A datapath classification method for FPGA-based scientific application accelerator systems Proceedings - 2010 International Conference On Field-Programmable Technology, Fpt'10. 441-444. DOI: 10.1109/FPT.2010.5681455  0.01
2010 Hasegawa E, Hiroi N, Osawa C, Tayama E, Iwamoto H. Application of biphasic reaction procedure using ferric chloride dissolved in an imidazolium salt and benzotrifluoride (FeIm-BTF procedure) to aza-Prins cyclization reaction Tetrahedron Letters. 51: 6535-6538. DOI: 10.1016/j.tetlet.2010.10.018  0.01
2010 Hiroi N, Yamashita K, Yoshida E, Usui S, Ichijo T, Ouchi H, Higa M. A type 2 diabetic patient with emphysematous cystitis, pyogenic spondylitis, and multiple muscle abscesses Journal of the Medical Society of Toho University. 57: 324-329.  0.01
2010 Yoshifuji A, Higa M, Kobayashi Y, Yamashita K, Usui S, Ichijo T, Ouchi H, Yamane T, Hiroi N. A case of type 1 diabetic patient with focal fatty liver which was improved by glycemic control Journal of the Japan Diabetes Society. 53: 24-29.  0.01
2008 Yoshimi M, Nishikawa Y, Osana Y, Funahashi A, Hiroi N, Shibata Y, Yamada H, Kitano H, Amano H. Practical implementation of a network-based Stochastic biochemical simulation system on an FPGA Proceedings - 2008 International Conference On Field Programmable Logic and Applications, Fpl. 663-666. DOI: 10.1109/FPL.2008.4630034  0.01
2008 Otani T, Asaka N, Sue M, Yoshihara A, Usui S, Tsuchida Y, Hiroi N, Ouchi H, Higa M. A case of localized scleroderma with type 2 diabetes mellitus which has difficulty discrimination of diabetic digital sclerosis Journal of the Japan Diabetes Society. 51: 441-444.  0.01
2007 Yoshimi M, Nishikawa Y, Kojima T, Osana Y, Funahashi A, Hiroi N, Shibata Y, Yamada H, Kitano H, Amano H. A framework for implementing a network-based stochastic biochemical simulator on an FPGA Icfpt 2007 - International Conference On Field Programmable Technology. 193-200. DOI: 10.1109/FPT.2007.4439249  0.01
2006 Sugisawa N, Suzuki T, Hiroi N, Yamane T, Natori K, Kiguchi H, Kuraishi Y, Higa M. Primary bone malignant lymphoma: radiographic and magnetic resonance images. Internal Medicine (Tokyo, Japan). 45: 665-6. PMID 16755102 DOI: JST.JSTAGE/internalmedicine/45.1638  0.01
2006 Osana Y, Yoshimi M, Iwaoka Y, Kojima T, Nishikawa Y, Funahashi A, Hiroi N, Kitano H, Amano H, Shibata Y, Iwanaga N. Performance evaluation of an FPGA-based biochemical simulator ReCSiP Proceedings - 2006 International Conference On Field Programmable Logic and Applications, Fpl. 845-850. DOI: 10.1109/FPL.2006.311327  0.01
2005 Sonobe T, Hiroi N, Nakano Y, Fujita H. OPLEAF connecting optical fibers to high density optical IC Ieee/Leos Optical Mems 2005: International Conference On Optical Mems and Their Applications. 199-200. DOI: 10.1109/OMEMS.2005.1540148  0.01
2005 Osana Y, Fukushima T, Yoshimi M, Iwaoka Y, Funahashi A, Hiroi N, Shibata Y, Kitano H, Amano H. An FPGA-based, multi-model simulation method for biochemical systems Proceedings - 19th Ieee International Parallel and Distributed Processing Symposium, Ipdps 2005. 2005. DOI: 10.1109/IPDPS.2005.103  0.01
2005 Yoshimi M, Osana Y, Iwaoka Y, Funahashi A, Hiroi N, Shibata Y, Iwanaga N, Kitano H, Amano H. The design of scalable stochastic biochemical simulator on FPGA Proceedings - 2005 Ieee International Conference On Field Programmable Technology. 2005: 339-340. DOI: 10.1109/FPT.2005.1568590  0.01
2005 Osana Y, Fukushima T, Yoshimi M, Iwaoka Y, Funahashi A, Hiroi N, Shibata Y, Iwanaga N, Kitano H, Amano H. A framework for ODE-based multimodel biochemical simulations on an FPGA Proceedings - 2005 International Conference On Field Programmable Logic and Applications, Fpl. 2005: 574-577. DOI: 10.1109/FPL.2005.1515788  0.01
2005 Sonobe T, Hiroi N, Takenaka M, Nakano Y, Fujita H. OPLEAF high density fiber array for minimized lateral device spacing optical ICs Iet Conference Publications. 2005: 557-558. DOI: 10.1049/cp:20050607  0.01
2005 Hiroi N, Miyazaki Y, Terai H, Nakajima S, Saito S, Kaneko Y, Yamamuro W, Higa M. Apathetic hyperthyroidism with hypercalcemia: A case report Journal of the Medical Society of Toho University. 52: 341-346.  0.01
2005 Yoshihara A, Hiroi N, Terai H, Kikuchi N, Nakajima S, Ono K, Yamamuro W, Higa M. A case of pseudoaldosteronism with hypocalcemia Journal of the Medical Society of Toho University. 52: 72-77.  0.01
2004 Hiroi N, Saito S, Nakajima S, Kaneko Y, Kawai K, Egawa T, Kiguchi E, Yoshida-Hiroi M, Yamamuro W, Higa M. Splenic tuberculosis with tumor of the right hand due to skeletal tuberculosis Journal of the Medical Society of Toho University. 51: 238-243.  0.01
2004 Kaneko Y, Higa M, Hiroi N, Yamamuro W, Yoshino G. Fulminant type 1 diabetes mellitus: Report of two cases Journal of the Medical Society of Toho University. 51: 168-174.  0.01
2002 Takakura KI, Hiroi N, Suemasu T, Chichibu SF, Hasegawa F. Investigation of direct and indirect band gaps of [100]-oriented nearly strain-free β-FeSi2 films grown by molecular-beam epitaxy Applied Physics Letters. 80: 556-558. DOI: 10.1063/1.1432755  0.01
2001 Hiroi N, Suemasu T, Takakura K, Seki N, Hasegawa F. Direct growth of [100]-oriented high-quality β-FeSi2 films on Si(001) substrates by molecular beam epitaxy Japanese Journal of Applied Physics, Part 2: Letters. 40: L1008-L1011.  0.01
2000 Hiraoka M, Mitsumori M, Hiroi N, Ohno S, Tanaka Y, Kotsuka Y, Sugimachi K. Developmentof RF and microwave heating equipment and clinical applications to cancer treatment in Japan Ieee Transactions On Microwave Theory and Techniques. 48: 1789-1799.  0.01
2000 Takakura KI, Suemasu T, Hiroi N, Hasegawa F. Improvement of the electrical properties of β-FeSi2 films on Si (001) by high-temperature annealing Japanese Journal of Applied Physics, Part 2: Letters. 39: L233-L236.  0.01
1999 Suemasu T, Hiroi N, Fujii T, Takakura K, Hasegawa F. Growth of continuous and highly (100)-oriented β-FeSi2 films on Si(001) from Si/Fe multilayers with SiO2 capping and templates Japanese Journal of Applied Physics, Part 2: Letters. 38: L878-L882.  0.01
1999 Suemasu T, Iikura Y, Fujii T, Takakura K, Hiroi N, Hasegawa F. Improvement of 1.5 μm photoluminescence from reactive deposition epitaxy (RDE) grown β-FeSi2 balls in Si by high temperature annealing Japanese Journal of Applied Physics, Part 2: Letters. 38: L620-L622.  0.01
1998 Kawai Y, Kamiya H, Kobayashi H, Nagata H, Nakashima H, Yato M, Sano M, Oda Y, Hiroi N, Kanemitsu T, Naruse T. Complications of laparoscopic cholecystectomy for benign diseases of gallbladder with reference on resident training Journal of the Aichi Medical University Association. 26: 217-223.  0.01
1997 Ohara H, Izawa J, Kimura S, Hiroi N, Matsui H, Hirata N, Takahashi E. Induction of fruit set and growth of parthenocarpic 'Hayward' kiwifruit with plant growth regulators Journal of the Japanese Society For Horticultural Science. 66: 467-473.  0.01
1993 Hiroi N, Miyachi Y. [Statistical survey of acromegaly in Japan]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 51: 25-32. PMID 8459551  0.01
1993 Hiroi N, Miyachi Y. [Acromegaloid features]. RyåIkibetsu ShåKåGun Shirä«Zu. 152-3. PMID 7757542  0.01
1993 Hiroi N, Miyachi Y. [Acromegaly]. RyåIkibetsu ShåKåGun Shirä«Zu. 149-51. PMID 7757541  0.01
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