Peter Sorger - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
systems biology, cancer

297 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Patiño-Galindo JÁ, Filip I, Chowdhury R, Maranas CD, Sorger PK, AlQuraishi M, Rabadan R. Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2. Genome Medicine. 13: 124. PMID 34362430 DOI: 10.1186/s13073-021-00943-6  1
2021 Bouatta N, Sorger P, AlQuraishi M. Protein structure prediction by AlphaFold2: are attention and symmetries all you need? Acta Crystallographica. Section D, Structural Biology. 77: 982-991. PMID 34342271 DOI: 10.1107/S2059798321007531  1
2021 Plana D, Tian E, Cramer AK, Yang H, Carmack MM, Sinha MS, Bourgeois FT, Yu SH, Masse P, Boyer J, Kim M, Mo J, LeBoeuf NR, Li J, Sorger PK. Assessing the filtration efficiency and regulatory status of N95s and nontraditional filtering face-piece respirators available during the COVID-19 pandemic. Bmc Infectious Diseases. 21: 712. PMID 34325673 DOI: 10.1186/s12879-021-06008-8  0.01
2021 Rodriguez S, Sahin A, Schrank BR, Al-Lawati H, Costantino I, Benz E, Fard D, Albers AD, Cao L, Gomez AC, Evans K, Ratti E, Cudkowicz M, Frosch MP, Talkowski M, ... Sorger PK, et al. Genome-encoded cytoplasmic double-stranded RNAs, found in ALS-FTD brain, propagate neuronal loss. Science Translational Medicine. 13. PMID 34233951 DOI: 10.1126/scitranslmed.aaz4699  1
2021 McAvoy M, Bui AN, Hansen C, Plana D, Said JT, Yu Z, Yang H, Freake J, Van C, Krikorian D, Cramer A, Smith L, Jiang L, Lee KJ, Li SJ, ... ... Sorger PK, et al. 3D Printed frames to enable reuse and improve the fit of N95 and KN95 respirators. Bmc Biomedical Engineering. 3: 10. PMID 34099062 DOI: 10.1186/s42490-021-00055-7  0.01
2021 Liu D, Lin JR, Robitschek EJ, Kasumova GG, Heyde A, Shi A, Kraya A, Zhang G, Moll T, Frederick DT, Chen YA, Wang S, Schapiro D, Ho LL, Bi K, ... ... Sorger PK, et al. Evolution of delayed resistance to immunotherapy in a melanoma responder. Nature Medicine. PMID 33941922 DOI: 10.1038/s41591-021-01331-8  1
2021 Antonini MJ, Plana D, Srinivasan S, Atta L, Achanta A, Yang H, Cramer AK, Freake J, Sinha MS, Yu SH, LeBoeuf NR, Linville-Engler B, Sorger PK. A Crisis-Responsive Framework for Medical Device Development Applied to the COVID-19 Pandemic. Frontiers in Digital Health. 3. PMID 33899045 DOI: 10.3389/fdgth.2021.617106  0.01
2021 Kothakonda A, Atta L, Plana D, Ward F, Davis C, Cramer A, Moran R, Freake J, Tian E, Mazor O, Gorelik P, Van C, Hansen C, Yang H, Sinha MS, ... ... Sorger PK, et al. De novo Powered Air-Purifying Respirator Design and Fabrication for Pandemic Response. Medrxiv : the Preprint Server For Health Sciences. PMID 33821290 DOI: 10.1101/2021.03.25.21252076  0.01
2021 Vemulapalli V, Chylek LA, Erickson A, Pfeiffer A, Gabriel KH, LaRochelle J, Subramanian K, Cao R, Stegmaier K, Mohseni M, LaMarche MJ, Acker MG, Sorger PK, Gygi SP, Blacklow SC. Time resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling. Elife. 10. PMID 33755016 DOI: 10.7554/eLife.64251  1
2021 Jiang B, Gao Y, Che J, Lu W, Kaltheuner IH, Dries R, Kalocsay M, Berberich MJ, Jiang J, You I, Kwiatkowski N, Riching KM, Daniels DL, Sorger PK, Geyer M, et al. Discovery and resistance mechanism of a selective CDK12 degrader. Nature Chemical Biology. PMID 33753926 DOI: 10.1038/s41589-021-00765-y  1
2021 Mehta AK, Cheney EM, Hartl CA, Pantelidou C, Oliwa M, Castrillon JA, Lin JR, Hurst KE, de Oliveira Taveira M, Johnson NT, Oldham WM, Kalocsay M, Berberich MJ, Boswell SA, Kothari A, ... ... Sorger PK, et al. Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer. Nature Cancer. 2: 66-82. PMID 33738458 DOI: 10.1038/s43018-020-00148-7  1
2021 Rodriguez S, Hug C, Todorov P, Moret N, Boswell SA, Evans K, Zhou G, Johnson NT, Hyman BT, Sorger PK, Albers MW, Sokolov A. Machine learning identifies candidates for drug repurposing in Alzheimer's disease. Nature Communications. 12: 1033. PMID 33589615 DOI: 10.1038/s41467-021-21330-0  1
2021 Ietswaart R, Gyori BM, Bachman JA, Sorger PK, Churchman LS. GeneWalk identifies relevant gene functions for a biological context using network representation learning. Genome Biology. 22: 55. PMID 33526072 DOI: 10.1186/s13059-021-02264-8  1
2021 Färkkilä A, Rodríguez A, Oikkonen J, Gulhan DC, Nguyen H, Domínguez J, Ramos S, Mills CE, Perez-Villatoro F, Lazaro JB, Zhou J, Clairmont CS, Moreau LA, Park PJ, Sorger PK, et al. Heterogeneity and clonal evolution of acquired PARP inhibitor resistance in TP53- and BRCA1-deficient cells. Cancer Research. PMID 33514515 DOI: 10.1158/0008-5472.CAN-20-2912  0.01
2021 Jerby-Arnon L, Neftel C, Shore ME, Weisman HR, Mathewson ND, McBride MJ, Haas B, Izar B, Volorio A, Boulay G, Cironi L, Richman AR, Broye LC, Gurski JM, Luo CC, ... ... Sorger PK, et al. Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma. Nature Medicine. PMID 33495604 DOI: 10.1038/s41591-020-01212-6  0.01
2021 Kassamali B, Yu Z, Davis C, Carmack M, Bui AN, Said JT, Plana D, Yang H, Sorger P, LeBoeuf NR, LaChance AH. Conversion of Existing UVB Phototherapy Units to UVC Germicidal Chambers for N95 Decontamination: Lessons Learned. Photobiomodulation, Photomedicine, and Laser Surgery. PMID 33481669 DOI: 10.1089/photob.2020.4968  0.01
2021 Cramer AK, Plana D, Yang H, Carmack MM, Tian E, Sinha MS, Krikorian D, Turner D, Mo J, Li J, Gupta R, Manning H, Bourgeois FT, Yu SH, Sorger PK, et al. Analysis of SteraMist ionized hydrogen peroxide technology in the sterilization of N95 respirators and other PPE. Scientific Reports. 11: 2051. PMID 33479334 DOI: 10.1038/s41598-021-81365-7  0.01
2021 Hemming ML, Coy S, Lin JR, Andersen JL, Przybyl J, Mazzola E, Abdelhamid Ahmed AH, van de Rijn M, Sorger PK, Armstrong SA, Demetri GD, Santagata S. HAND1 and BARX1 act as transcriptional and anatomic determinants of malignancy in gastrointestinal stromal tumor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33451979 DOI: 10.1158/1078-0432.CCR-20-3538  1
2020 Hoffer J, Rashid R, Muhlich JL, Chen YA, Russell DPW, Ruokonen J, Krueger R, Pfister H, Santagata S, Sorger PK. Minerva: a light-weight, narrative image browser for multiplexed tissue images. Journal of Open Source Software. 5. PMID 33768192 DOI: 10.21105/joss.02579  1
2020 Ringel AE, Drijvers JM, Baker GJ, Catozzi A, García-Cañaveras JC, Gassaway BM, Miller BC, Juneja VR, Nguyen TH, Joshi S, Yao CH, Yoon H, Sage PT, LaFleur MW, Trombley JD, ... ... Sorger PK, et al. Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. Cell. PMID 33301708 DOI: 10.1016/j.cell.2020.11.009  1
2020 Magid SA, Jang WD, Schapiro D, Wei D, Tompkin J, Sorger PK, Pfister H. Channel Embedding for Informative Protein Identification from Highly Multiplexed Images. Medical Image Computing and Computer-Assisted Intervention : Miccai ... International Conference On Medical Image Computing and Computer-Assisted Intervention. 12265: 3-13. PMID 33283211 DOI: 10.1007/978-3-030-59722-1_1  0.01
2020 Keenan TE, Li T, Vallius T, Guerriero JL, Tayob N, Kochupurakkal BS, Davis J, Pastorello RG, Tahara RK, Anderson L, Conway J, He MX, Shannon E, Godin R, Sorger PK, et al. Clinical efficacy and molecular response correlates of the WEE1 inhibitor adavosertib combined with cisplatin in patients with metastatic triple-negative breast cancer (mTNBC). Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33257427 DOI: 10.1158/1078-0432.CCR-20-3089  0.01
2020 Iorgulescu JB, Gokhale PC, Speranza MC, Eschle BK, Poitras MJ, Wilkens MK, Soroko KM, Chhoeu C, Knott A, Gao Y, Lim-Fat MJ, Baker GJ, Bonal DM, Nguyen QD, Grant GRL, ... ... Sorger PK, et al. Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33239433 DOI: 10.1158/1078-0432.CCR-20-2291  0.01
2020 Palmer AC, Plana D, Sorger PK. Comparing the Efficacy of Cancer Therapies between Subgroups in Basket Trials. Cell Systems. 11: 449-460.e2. PMID 33220857 DOI: 10.1016/j.cels.2020.09.003  0.01
2020 Gerosa L, Chidley C, Fröhlich F, Sanchez G, Lim SK, Muhlich J, Chen JY, Vallabhaneni S, Baker GJ, Schapiro D, Atanasova MI, Chylek LA, Shi T, Yi L, Nicora CD, ... ... Sorger PK, et al. Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells. Cell Systems. PMID 33113355 DOI: 10.1016/j.cels.2020.10.002  1
2020 Berginski ME, Moret N, Liu C, Goldfarb D, Sorger PK, Gomez SM. The Dark Kinase Knowledgebase: an online compendium of knowledge and experimental results of understudied kinases. Nucleic Acids Research. PMID 33079988 DOI: 10.1093/nar/gkaa853  0.01
2020 Aid M, Busman-Sahay K, Vidal SJ, Maliga Z, Bondoc S, Starke C, Terry M, Jacobson CA, Wrijil L, Ducat S, Brook OR, Miller AD, Porto M, Pellegrini KL, Pino M, ... ... Sorger PK, et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell. PMID 33065030 DOI: 10.1016/j.cell.2020.10.005  0.01
2020 Baker GJ, Muhlich JL, Palaniappan SK, Moore JK, Davis SH, Santagata S, Sorger PK. SYLARAS: A Platform for the Statistical Analysis and Visual Display of Systemic Immunoprofiling Data and Its Application to Glioblastoma. Cell Systems. PMID 32898474 DOI: 10.1016/J.Cels.2020.08.001  1
2020 Mostaghimi A, Antonini MJ, Plana D, Anderson PD, Beller B, Boyer EW, Fannin A, Freake J, Oakley R, Sinha MS, Smith L, Van C, Yang H, Sorger PK, LeBoeuf NR, et al. Regulatory and Safety Considerations in Deploying a Locally Fabricated, Reusable Face Shield in a Hospital Responding to the COVID-19 Pandemic. Med (New York, N.Y.). PMID 32838357 DOI: 10.1016/J.Medj.2020.06.003  0.01
2020 Liu Y, Ferguson FM, Li L, Kuljanin M, Mills CE, Subramanian K, Harshbarger W, Gondi S, Wang J, Sorger PK, Mancias JD, Gray NS, Westover KD. Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing. Cell Chemical Biology. PMID 32755567 DOI: 10.1016/J.Chembiol.2020.07.011  1
2020 Palmer AC, Plana D, Gao H, Korn JM, Yang G, Green J, Zhang X, Velazquez R, McLaughlin ME, Ruddy DA, Kowal C, Goldovitz J, Bullock C, Rivera S, Rakiec DP, ... ... Sorger PK, et al. A proof of concept for biomarker-guided targeted therapy against ovarian cancer based on patient-derived tumor xenografts. Cancer Research. PMID 32747364 DOI: 10.1158/0008-5472.Can-19-3850  0.01
2020 McAvoy M, Bui AN, Hansen C, Plana D, Said JT, Yu Z, Yang H, Freake J, Van C, Krikorian D, Cramer A, Smith L, Jiang L, Lee KJ, Li SJ, ... ... Sorger PK, et al. 3D Printed frames to enable reuse and improve the fit of N95 and KN95 respirators. Medrxiv : the Preprint Server For Health Sciences. PMID 32743606 DOI: 10.1101/2020.07.20.20151019  0.01
2020 Plana D, Tian E, Cramer AK, Yang H, Carmack MM, Sinha MS, Bourgeois FT, Yu SH, Masse P, Boyer J, Kim M, Mo J, LeBoeuf NR, Li J, Sorger PK. Assessing the quality of nontraditional N95 filtering face-piece respirators available during the COVID-19 pandemic. Medrxiv : the Preprint Server For Health Sciences. PMID 32743596 DOI: 10.1101/2020.07.25.20161968  0.01
2020 Zervantonakis IK, Poskus MD, Scott AL, Selfors LM, Lin JR, Dillon DA, Pathania S, Sorger PK, Mills GB, Brugge JS. Fibroblast-tumor cell signaling limits HER2 kinase therapy response via activation of MTOR and antiapoptotic pathways. Proceedings of the National Academy of Sciences of the United States of America. PMID 32601199 DOI: 10.1073/Pnas.2000648117  1
2020 Izar B, Tirosh I, Stover EH, Wakiro I, Cuoco MS, Alter I, Rodman C, Leeson R, Su MJ, Shah P, Iwanicki M, Walker SR, Kanodia A, Melms JC, Mei S, ... ... Sorger PK, et al. A single-cell landscape of high-grade serous ovarian cancer. Nature Medicine. PMID 32572264 DOI: 10.1038/S41591-020-0926-0  1
2020 Sinha MS, Bourgeois FT, Sorger PK. Personal Protective Equipment for COVID-19: Distributed Fabrication and Additive Manufacturing. American Journal of Public Health. e1-e3. PMID 32552025 DOI: 10.2105/AJPH.2020.305753  0.01
2020 Mostaghimi A, Antonini MJ, Plana D, Anderson PD, Beller B, Boyer EW, Fannin A, Freake J, Oakley R, Sinha MS, Smith L, Van C, Yang H, Sorger P, LeBoeuf NR, et al. Rapid prototyping and clinical testing of a reusable face shield for health care workers responding to the COVID-19 pandemic. Medrxiv : the Preprint Server For Health Sciences. PMID 32511612 DOI: 10.1101/2020.04.11.20061960  0.01
2020 Cramer A, Plana D, Yang HL, Carmack M, Tian E, Sinha MS, Krikorian D, Turner D, Mo J, Li J, Gupta R, Manning H, Bourgeois FT, Yu SH, Sorger P, et al. Analysis of SteraMist ionized hydrogen peroxide technology in the sterilization of N95 respirators and other PPE: a quality improvement study. Medrxiv : the Preprint Server For Health Sciences. PMID 32511480 DOI: 10.1101/2020.04.19.20069997  0.01
2020 Chandrashekar A, Liu J, Martinot AJ, McMahan K, Mercado NB, Peter L, Tostanoski LH, Yu J, Maliga Z, Nekorchuk M, Busman-Sahay K, Terry M, Wrijil LM, Ducat S, Martinez DR, ... ... Sorger PK, et al. SARS-CoV-2 infection protects against rechallenge in rhesus macaques. Science (New York, N.Y.). PMID 32434946 DOI: 10.1126/Science.Abc4776  1
2020 Färkkilä A, Gulhan DC, Casado J, Jacobson CA, Nguyen H, Kochupurakkal B, Maliga Z, Yapp C, Chen YA, Schapiro D, Zhou Y, Graham JR, Dezube BJ, Munster P, Santagata S, ... ... Sorger PK, et al. Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer. Nature Communications. 11: 2543. PMID 32424117 DOI: 10.1038/S41467-020-16344-Z  0.01
2020 Gray NS, Teng M, Jiang J, He Z, Kwiatkowski NP, Donovan KA, Mills CE, Victor C, Hatcher JM, Fischer ES, Sorger PK, Zhang T. Development of CDK2 and CDK5 Dual Degrader TMX-2172. Angewandte Chemie (International Ed. in English). PMID 32415712 DOI: 10.1002/Anie.202004087  1
2020 Rozenblatt-Rosen O, Regev A, Oberdoerffer P, Nawy T, Hupalowska A, Rood JE, Ashenberg O, Cerami E, Coffey RJ, Demir E, Ding L, Esplin ED, Ford JM, Goecks J, Ghosh S, ... ... Sorger PK, et al. The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution. Cell. 181: 236-249. PMID 32302568 DOI: 10.1016/J.Cell.2020.03.053  1
2020 Schauer NJ, Liu X, Magin RS, Doherty LM, Chan WC, Ficarro SB, Hu W, Roberts RM, Iacob RE, Stolte B, Giacomelli AO, Perera S, McKay K, Boswell SA, Weisberg EL, ... ... Sorger PK, et al. Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism. Scientific Reports. 10: 5324. PMID 32210275 DOI: 10.1038/S41598-020-62076-X  1
2020 Färkkilä A, Gulhan DC, Casado J, Jacobson CA, Nguyen H, Kochupurakkal B, Maliga Z, Yapp C, Chen YA, Schapiro D, Zhou Y, Graham JR, Dezube BJ, Munster P, Santagata S, ... ... Sorger PK, et al. Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer. Nature Communications. 11: 1459. PMID 32193378 DOI: 10.1038/S41467-020-15315-8  0.01
2020 Hemming ML, Nathenson MJ, Lin JR, Mei S, Du Z, Malik K, Marino-Enriquez A, Jagannathan JP, Sorger PK, Bertagnolli M, Sicinska E, Demetri GD, Santagata S. Response and mechanisms of resistance to larotrectinib and selitrectinib in metastatic undifferentiated sarcoma harboring oncogenic fusion of . Jco Precision Oncology. 4: 79-90. PMID 32133433 DOI: 10.1200/po.19.00287  1
2020 Gaglia G, Rashid R, Yapp C, Joshi GN, Li CG, Lindquist SL, Sarosiek KA, Whitesell L, Sorger PK, Santagata S. HSF1 phase transition mediates stress adaptation and cell fate decisions. Nature Cell Biology. PMID 32015439 DOI: 10.1038/S41556-019-0458-3  0.01
2020 Lyashenko E, Niepel M, Dixit PD, Lim SK, Sorger PK, Vitkup D. Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks. Elife. 9. PMID 31961323 DOI: 10.7554/Elife.50342  1
2020 Du G, Rao S, Gurbani D, Henning NJ, Jiang J, Che J, Yang A, Ficarro SB, Marto JA, Aguirre AJ, Sorger PK, Westover KD, Zhang T, Gray NS. Structure-based design of a potent and selective covalent inhibitor for SRC kinase that targets a p-Loop cysteine. Journal of Medicinal Chemistry. PMID 31935084 DOI: 10.1021/Acs.Jmedchem.9B01502  1
2020 Cunningham JM, Koytiger G, Sorger PK, AlQuraishi M. Biophysical prediction of protein-peptide interactions and signaling networks using machine learning. Nature Methods. PMID 31907444 DOI: 10.1038/S41592-019-0687-1  1
2020 Baker GJ, Palaniappan SK, Moore JK, Davis SH, Santagata S, Sorger PK. Abstract A9: Systemic immune response profiling with SYLARAS implicates a role for CD45R/B220+ CD8+ T cells in glioblastoma immunology Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm19-A9  1
2020 Guerriero JL, Mehta AK, Cheney EM, Castrillon JA, Lin J, Taveira MdO, Sonzogni O, Pantelidou C, Hartl CA, Oldham WM, Johnson NT, Boswell SA, Kalocsay M, Berberich MJ, Mei S, ... ... Sorger P, et al. Abstract P5-04-01: PARP inhibition modulates the infiltration, phenotype and function of tumor-associated macrophages (TAMs) in BRCA-associated breast cancer and can be augmented by harnessing the anti-tumor potential of TAMs Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P5-04-01  0.01
2020 Ericson N, Podyminogin R, Chow J, Lin J, Chen Y, Maliga Z, Sorger P, Teplitz K, Kaldjian E, George T. Abstract P4-06-09: Pick-Seq®: Multi-parameter imaging combined with RNA sequencing of tissue section micro-regions for spatial analysis in breast carcinoma Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P4-06-09  0.01
2019 Melms JC, Vallabhaneni S, Mills CE, Yapp C, Chen JY, Morelli E, Waszyk P, Kumar S, Deming D, Moret N, Rodriguez S, Subramanian K, Rogava M, Cartwright ANR, Luoma A, ... ... Sorger PK, et al. Inhibition of Haspin kinase promotes cell-intrinsic and extrinsic anti-tumor activity. Cancer Research. PMID 31882401 DOI: 10.1158/0008-5472.Can-19-2330  0.01
2019 Rashid R, Gaglia G, Chen YA, Lin JR, Du Z, Maliga Z, Schapiro D, Yapp C, Muhlich J, Sokolov A, Sorger P, Santagata S. Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer. Scientific Data. 6: 323. PMID 31848351 DOI: 10.1038/S41597-019-0332-Y  1
2019 Chopra SS, Jenney A, Palmer A, Niepel M, Chung M, Mills C, Sivakumaren SC, Liu Q, Chen JY, Yapp C, Asara JM, Gray NS, Sorger PK. Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells. Cell Systems. PMID 31812693 DOI: 10.1016/J.Cels.2019.11.001  1
2019 Wang S, Lin JR, Sontag ED, Sorger PK. Inferring reaction network structure from single-cell, multiplex data, using toric systems theory. Plos Computational Biology. 15: e1007311. PMID 31809500 DOI: 10.1371/Journal.Pcbi.1007311  1
2019 Palmer AC, Chidley C, Sorger PK. A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity. Elife. 8. PMID 31742555 DOI: 10.7554/eLife.50036  0.01
2019 Li Z, Pinch BJ, Olson CM, Donovan KA, Nowak RP, Mills CE, Scott DA, Doctor ZM, Eleuteri NA, Chung M, Sorger PK, Fischer ES, Gray NS. Development and Characterization of a Wee1 Kinase Degrader. Cell Chemical Biology. PMID 31735695 DOI: 10.1016/J.Chembiol.2019.10.013  1
2019 Du Z, Lin JR, Rashid R, Maliga Z, Wang S, Aster JC, Izar B, Sorger PK, Santagata S. Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging. Nature Protocols. PMID 31534232 DOI: 10.1038/S41596-019-0206-Y  1
2019 Krueger R, Beyer J, Jang WD, Kim NW, Sokolov A, Sorger PK, Pfister H. Facetto: Combining Unsupervised and Supervised Learning for Hierarchical Phenotype Analysis in Multi-Channel Image Data. Ieee Transactions On Visualization and Computer Graphics. PMID 31514138 DOI: 10.1109/Tvcg.2019.2934547  0.01
2019 Niepel M, Hafner M, Mills CE, Subramanian K, Williams EH, Chung M, Gaudio B, Barrette AM, Stern AD, Hu B, Korkola JE, Gray JW, Birtwistle MR, Heiser LM, ... Sorger PK, et al. A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines. Cell Systems. PMID 31302153 DOI: 10.1016/J.Cels.2019.06.005  1
2019 Hafner M, Mills CE, Subramanian K, Chen C, Chung M, Boswell SA, Everley RA, Liu C, Walmsley CS, Juric D, Sorger PK. Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity. Cell Chemical Biology. PMID 31178407 DOI: 10.1016/J.Chembiol.2019.05.005  1
2019 Wang H, Sheehan RP, Palmer AC, Everley RA, Boswell SA, Ron-Harel N, Ringel AE, Holton KM, Jacobson CA, Erickson AR, Maliszewski L, Haigis MC, Sorger PK. Adaptation of Human iPSC-Derived Cardiomyocytes to Tyrosine Kinase Inhibitors Reduces Acute Cardiotoxicity via Metabolic Reprogramming. Cell Systems. PMID 31078528 DOI: 10.1016/J.Cels.2019.03.009  0.01
2019 Todorov PV, Gyori BM, Bachman JA, Sorger PK. INDRA-IPM: interactive pathway modeling using natural language with automated assembly. Bioinformatics (Oxford, England). PMID 31070726 DOI: 10.1093/bioinformatics/btz289  1
2019 Rao S, Gurbani D, Du G, Everley RA, Browne CM, Chaikuad A, Li T, Schröder M, Gondi S, Ficarro SB, Sim T, Kim ND, Berberich MJ, Knapp S, Marto JA, ... ... Sorger PK, et al. Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome. Cell Chemical Biology. PMID 30982749 DOI: 10.1016/J.Chembiol.2019.02.021  1
2019 Moret N, Clark NA, Hafner M, Wang Y, Lounkine E, Medvedovic M, Wang J, Gray N, Jenkins J, Sorger PK. Cheminformatics Tools for Analyzing and Designing Optimized Small-Molecule Collections and Libraries. Cell Chemical Biology. PMID 30956147 DOI: 10.1016/J.Chembiol.2019.02.018  1
2019 Ferguson FM, Doctor ZM, Ficarro SB, Browne CM, Marto JA, Johnson JL, Yaron TM, Cantley LC, Kim ND, Sim T, Berberich MJ, Kalocsay M, Sorger PK, Gray NS. Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity. Cell Chemical Biology. PMID 30930164 DOI: 10.1016/J.Chembiol.2019.02.015  1
2019 Olson CM, Liang Y, Leggett A, Park WD, Li L, Mills CE, Elsarrag SZ, Ficarro SB, Zhang T, Düster R, Geyer M, Sim T, Marto JA, Sorger PK, Westover KD, et al. Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype. Cell Chemical Biology. PMID 30905681 DOI: 10.1016/J.Chembiol.2019.02.012  1
2019 Rao S, Du G, Hafner M, Subramanian K, Sorger PK, Gray NS. A multi-targeted probe-based strategy to identify signaling vulnerabilities in cancers. The Journal of Biological Chemistry. PMID 30858179 DOI: 10.1074/Jbc.Ra118.006805  1
2019 Rapisuwon S, Izar B, Batenchuk C, Avila A, Mei S, Sorger P, Parks JM, Cooper SJ, Wagner D, Zeck JC, Charabaty AJ, Atkins MB. Exceptional response and multisystem autoimmune-like toxicities associated with the same T cell clone in a patient with uveal melanoma treated with immune checkpoint inhibitors. Journal For Immunotherapy of Cancer. 7: 61. PMID 30832716 DOI: 10.1186/S40425-019-0533-0  0.01
2019 Song Y, Subramanian K, Berberich MJ, Rodriguez S, Latorre IJ, Luria CM, Everley R, Albers MW, Mitchison TJ, Sorger PK. A dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line. Scientific Data. 6: 190016. PMID 30778261 DOI: 10.1038/Sdata.2019.16  1
2019 Lyashenko E, Niepel M, Dixit PD, Lim SK, Sorger PK, Vitkup D. Author response: Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks Elife. DOI: 10.7554/Elife.50342.Sa2  1
2019 Ghassemifar S, Hashambhoy-Ramsay Y, Yuzugullu H, Utermark T, Paragas V, Maiwald T, Luus L, Razlog M, Hudson H, Chai D, Schoeberl B, Reynolds CP, Sorger P, Sawyer AJ, Drummond DC, et al. Abstract 700: Development of a second-generation TRAIL agonist and predictive biomarker profile for colorectal cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-700  1
2019 Podyminogin R, Ericson N, Lin J, Chen Y, Sorger P, Kaldjian E, George T, U'Ren L. Abstract 489: Multi-parameter tissue section imaging and retrieval of image-defined micro-regions for RNA sequencing using the RareCyte® platform Immunology. DOI: 10.1158/1538-7445.Sabcs18-489  0.01
2019 Mills CE, Hafner MA, Subramanian K, Chen C, Chung M, Boswell SA, Everley RA, Liu C, Walmsley CS, Juric D, Sorger PK. Abstract 4432: Multi-omics profiling establishes the polypharmacology of FDA Approved CDK4/6 inhibitors and its impact on drug response Cancer Research. 79: 4432-4432. DOI: 10.1158/1538-7445.Sabcs18-4432  1
2019 Farkkila A, Lin JR, Casado J, Nguyen H, Zhou Y, Graham JR, Dezube BJ, Waggoner S, Munster P, Fleming GF, Santagata S, Matulonis UA, Sorger PK, Swisher EM, D’Andrea AD, et al. Abstract 4487: Association of the tumor-immune microenvironment with response to niraparib and pembrolizumab in relapsed, platinum-resistant ovarian cancer Cancer Research. 79: 4487-4487. DOI: 10.1158/1538-7445.Am2019-4487  1
2019 Gerosa L, Chidley C, Froehlich F, Sanchez G, Lim SK, Muhlich J, Chen J, Baker GJ, Schapiro D, Shi T, Yi L, Nicora CD, Qian W, Wiley HS, Sorger P. Abstract LB-B09: ERK pulses drive non-genetic resistance in drug-adapted BRAFV600E melanoma cells Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-Lb-B09  1
2019 Chopra SS, Jenney A, Palmer A, Niepel M, Chung M, Mills C, Sivakumaren SC, Liu Q, Chen J, Yapp C, Gray NS, Sorger PK. Abstract B103: Torin2 and related analogs exploit replicative and checkpoint vulnerabilities to induce death of triple-negative breast cancer cells Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-B103  1
2018 Dunn IF, Du Z, Touat M, Sisti MB, Wen PY, Umeton R, Dubuc AM, Ducar M, Canoll PD, Severson E, Elvin JA, Ramkissoon SH, Lin JR, Cabrera L, Acevedo B, ... Sorger PK, et al. Mismatch repair deficiency in high-grade meningioma: a rare but recurrent event associated with dramatic immune activation and clinical response to PD-1 blockade. Jco Precision Oncology. 2018. PMID 30801050 DOI: 10.1200/PO.18.00190  1
2018 Jerby-Arnon L, Shah P, Cuoco MS, Rodman C, Su MJ, Melms JC, Leeson R, Kanodia A, Mei S, Lin JR, Wang S, Rabasha B, Liu D, Zhang G, Margolais C, ... ... Sorger PK, et al. A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade. Cell. 175: 984-997.e24. PMID 30388455 DOI: 10.1016/J.Cell.2018.09.006  1
2018 Sorger PK, Lin JR, Izar B, Wang S, Yapp C, Mei S, Shah PM, Santagata S. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. Elife. 7. PMID 29993362 DOI: 10.7554/Elife.31657  1
2018 Bachman JA, Gyori BM, Sorger PK. FamPlex: a resource for entity recognition and relationship resolution of human protein families and complexes in biomedical text mining. Bmc Bioinformatics. 19: 248. PMID 29954318 DOI: 10.1186/s12859-018-2211-5  1
2018 Sampattavanich S, Steiert B, Kramer BA, Gyori BM, Albeck JG, Sorger PK. Encoding Growth Factor Identity in the Temporal Dynamics of FOXO3 under the Combinatorial Control of ERK and AKT Kinases. Cell Systems. PMID 29886111 DOI: 10.1016/j.cels.2018.05.004  1
2018 Koch PD, Miller HR, Yu G, Tallarico JA, Sorger PK, Wang Y, Feng Y, Thomas JR, Ross NT, Mitchison T. A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling. Acs Chemical Biology. PMID 29553248 DOI: 10.1021/Acschembio.7B01060  1
2018 Jones DS, Jenney AP, Joughin BA, Sorger PK, Lauffenburger DA. Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition. Science Signaling. 11. PMID 29511118 DOI: 10.1126/Scisignal.Aal1601  1
2018 Coy S, Rashid R, Lin JR, Du Z, Donson AM, Hankinson TC, Foreman NK, Manley PE, Kieran MW, Reardon DA, Sorger PK, Santagata S. Multiplexed Immunofluorescence Reveals Potential PD-1/PD-L1 Pathway Vulnerabilities in Craniopharyngioma. Neuro-Oncology. PMID 29509940 DOI: 10.1093/Neuonc/Noy035  1
2018 Gonzalez Herrera KN, Zaganjor E, Ishikawa Y, Spinelli JB, Yoon H, Lin JR, Satterstrom FK, Ringel A, Mulei S, Souza A, Gorham JM, Benson CC, Seidman JG, Sorger PK, Clish CB, et al. Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3. Cell Reports. 22: 1945-1955. PMID 29466723 DOI: 10.1016/J.Celrep.2018.01.076  1
2018 Keenan AB, Jenkins SL, Jagodnik KM, Koplev S, He E, Torre D, Wang Z, Dohlman AB, Silverstein MC, Lachmann A, Kuleshov MV, Ma'ayan A, Stathias V, Terryn R, Cooper D, ... ... Sorger PK, et al. The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations. Cell Systems. 6: 13-24. PMID 29199020 DOI: 10.1016/J.Cels.2017.11.001  1
2018 Palmer AC, Chabner BA, Sorger P. The effect of patient-to-patient variability in drug response on combination cancer therapies, from 1961 to today. Journal of Clinical Oncology. 36. DOI: 10.1200/Jco.2018.36.15_Suppl.E14552  0.01
2018 Mills C, Hafner M, Subramanian K, Chen C, Chung M, Boswell S, Everley R, Walmsley C, Juric D, Sorger P. Abstract PD1-12: Omics profiling of CDK4/6 inhibitors reveals functionally important secondary targets of abemaciclib Cancer Research. 16. DOI: 10.1158/1538-7445.Sabcs18-Pd1-12  1
2018 Hafner M, Mills C, Subramanian K, Chen C, Boswell S, Everley R, Juric D, Sorger P. Abstract PD4-02: Advantageous polypharmacology of abemaciclib revealed by omics profiling of CDK4/6 inhibitors Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-Pd4-02  1
2018 Farkkila A, Chopra SS, Lin J, Maliga Z, Koruchupakkal B, Strickland KC, Howitt BE, Santagata S, Matulonis UA, Elias K, Swisher EM, Konstantinopoulos PA, Sorger P, D'Andrea AD. Abstract 139: DNA damage and immunoprofiling with highly multiplexed tissue immunofluorescence (t-CycIF) in high-grade serous ovarian cancer Cancer Research. 78: 139-139. DOI: 10.1158/1538-7445.Am2018-139  0.01
2018 Touat M, Dubuc A, Meredith D, Tsuji J, Mills C, Gaffey S, Geduldig J, Watkinson F, Pelton K, Malinowski S, Lennon N, Sorger P, Trippa L, Ramkissoon S, Reardon D, et al. Innv-13. Allele: A Consortium For Prospective Genomics And Functional Diagnostics To Guide Patient Care And Trial Analysis In Newly-Diagnosed Glioblastoma Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy148.587  0.01
2017 Palmer AC, Sorger PK. Combination Cancer Therapy Can Confer Benefit via Patient-to-Patient Variability without Drug Additivity or Synergy. Cell. 171: 1678-1691.e13. PMID 29245013 DOI: 10.1016/j.cell.2017.11.009  0.01
2017 Gyori BM, Bachman JA, Subramanian K, Muhlich JL, Galescu L, Sorger PK. From word models to executable models of signaling networks using automated assembly. Molecular Systems Biology. 13: 954. PMID 29175850 DOI: 10.15252/Msb.20177651  1
2017 Hafner M, Heiser LM, Williams EH, Niepel M, Wang NJ, Korkola JE, Gray JW, Sorger PK. Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics. Scientific Data. 4: 170166. PMID 29112189 DOI: 10.1038/sdata.2017.166  1
2017 Niepel M, Hafner M, Duan Q, Wang Z, Paull EO, Chung M, Lu X, Stuart JM, Golub TR, Subramanian A, Ma'ayan A, Sorger PK. Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling. Nature Communications. 8: 1186. PMID 29084964 DOI: 10.1038/S41467-017-01383-W  1
2017 Clark NA, Hafner M, Kouril M, Williams EH, Muhlich JL, Pilarczyk M, Niepel M, Sorger PK, Medvedovic M. GRcalculator: an online tool for calculating and mining dose-response data. Bmc Cancer. 17: 698. PMID 29065900 DOI: 10.1186/s12885-017-3689-3  1
2017 Werbin JL, Avendaño MS, Becker V, Jungmann R, Yin P, Danuser G, Sorger PK. Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane. Scientific Reports. 7: 12150. PMID 28939861 DOI: 10.1038/S41598-017-12257-Y  1
2017 Hafner M, Niepel M, Subramanian K, Sorger PK. Designing Drug-Response Experiments and Quantifying their Results. Current Protocols in Chemical Biology. 9: 96-116. PMID 28628201 DOI: 10.1002/Cpch.19  1
2017 Niepel M, Hafner M, Chung M, Sorger PK. Measuring Cancer Drug Sensitivity and Resistance in Cultured Cells. Current Protocols in Chemical Biology. 9: 55-74. PMID 28628199 DOI: 10.1002/cpch.21  1
2017 Hafner M, Niepel M, Sorger PK. Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics. Nature Biotechnology. 35: 500-502. PMID 28591115 DOI: 10.1038/nbt.3882  1
2017 Suderman R, Bachman JA, Smith A, Sorger PK, Deeds EJ. Fundamental trade-offs between information flow in single cells and cellular populations. Proceedings of the National Academy of Sciences of the United States of America. PMID 28500273 DOI: 10.1073/Pnas.1615660114  1
2017 Foijer F, Albacker LA, Bakker B, Spierings DC, Yue Y, Xie SZ, Davis SH, Lutum-Jehle A, Takemoto D, Hare B, Furey B, Bronson RT, Lansdorp PM, Bradley A, Sorger PK. Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma. Elife. 6. PMID 28318489 DOI: 10.7554/eLife.20873  1
2017 Fallahi-Sichani M, Becker V, Izar B, Baker GJ, Lin JR, Boswell SA, Shah P, Rotem A, Garraway LA, Sorger PK. Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de-differentiated state. Molecular Systems Biology. 13: 905. PMID 28069687 DOI: 10.15252/Msb.20166796  1
2017 Lin J, Izar B, Hawthorne S, Nordberg J, Kaldjian E, Sorger P. Abstract B21: Probing tumor heterogeneity and immune infiltration with Cyclic Immunofluorescence (CycIF), a robust, multiplexed imaging method Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-B21  0.04
2017 Fallahi-Sichani M, Becker V, Izar B, Baker GJ, Lin J, Boswell SA, Garraway LA, Sorger PK. Abstract PR17: Single-cell analysis reveals an adaptive, slowly-dividing, de-differentiated, drug-resistant cell state selectively inhibitable by drug combinations Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-Pr17  1
2017 Hafner M, Niepel M, Sorger P. Abstract P6-07-33: Metrics of drug sensitivity based on growth rate inhibition correct for the confounding effects of variable division rates Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P6-07-33  1
2017 Mills C, Hafner M, Sorger P. Abstract P4-08-02: Integration of transcriptomic, proteomic and drug response data in triple negative breast cancer cell lines and PDX models Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P4-08-02  1
2017 Niepel M, Hafner M, Duan Q, Subramanian A, Ma'ayan A, Sorger PK. Abstract IA05: New methods and better theory for pre-clinical cancer pharmacogenomics Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-Ia05  1
2017 Fallahi-Sichani M, Becker V, Izar B, Baker GJ, Lin J, Boswell SA, Garraway LA, Sorger PK. Abstract 5561: Single-cell analysis reveals an adaptive, transiently heritable, slowly-dividing, drug-resistant state inhibitable by drug combinations Cancer Research. 77: 5561-5561. DOI: 10.1158/1538-7445.Am2017-5561  1
2017 Chopra S, Niepel M, Jenney A, Hafner M, Sorger P. Abstract 142: Exploiting replicative vulnerabilities to counter incomplete responses to PI3K/Akt/mTOR inhibition Cancer Research. 77: 142-142. DOI: 10.1158/1538-7445.Am2017-142  1
2017 Rao S, Li T, Everley R, Du G, Sorger P, Gray N. Abstract 1222: Developing kinase inhibitors with polypharmacological profiles for the treatment of resistant cancers Cancer Research. 77: 1222-1222. DOI: 10.1158/1538-7445.Am2017-1222  0.01
2016 Duan Q, Reid SP, Clark NR, Wang Z, Fernandez NF, Rouillard AD, Readhead B, Tritsch SR, Hodos R, Hafner M, Niepel M, Sorger PK, Dudley JT, Bavari S, Panchal RG, et al. L1000CDS(2): LINCS L1000 characteristic direction signatures search engine. Npj Systems Biology and Applications. 2. PMID 28413689 DOI: 10.1038/npjsba.2016.15  1
2016 Tan L, Gurbani D, Weisberg EL, Jones DS, Rao S, Singer WD, Bernard FM, Mowafy S, Jenney A, Du G, Nonami A, Griffin JD, Lauffenburger DA, Westover KD, Sorger PK, et al. Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors. Bioorganic & Medicinal Chemistry. PMID 28038940 DOI: 10.1016/J.Bmc.2016.11.034  1
2016 Tan L, Gurbani D, Weisberg EL, Hunter JC, Li L, Jones DS, Ficarro SB, Mowafy S, Tam CP, Rao S, Du G, Griffin JD, Sorger PK, Marto JA, Westover KD, et al. Structure-guided development of covalent TAK1 inhibitors. Bioorganic & Medicinal Chemistry. PMID 28011204 DOI: 10.1016/J.Bmc.2016.11.035  1
2016 Lin JR, Fallahi-Sichani M, Chen JY, Sorger PK. Cyclic Immunofluorescence (CycIF), A Highly Multiplexed Method for Single-cell Imaging. Current Protocols in Chemical Biology. 8: 251-264. PMID 27925668 DOI: 10.1002/cpch.14  1
2016 Jones DS, Jenney AP, Swantek JL, Burke JM, Lauffenburger DA, Sorger PK. Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activation. Nature Chemical Biology. PMID 27820799 DOI: 10.1038/nchembio.2211  1
2016 Shi T, Niepel M, McDermott JE, Gao Y, Nicora CD, Chrisler WB, Markillie LM, Petyuk VA, Smith RD, Rodland KD, Sorger PK, Qian WJ, Wiley HS. Conservation of protein abundance patterns reveals the regulatory architecture of the EGFR-MAPK pathway. Science Signaling. 9: rs6. PMID 27405981 DOI: 10.1126/Scisignal.Aaf0891  1
2016 AlQuraishi M, Sorger PK. Reproducibility will only come with data liberation. Science Translational Medicine. 8: 339ed7. PMID 27194726 DOI: 10.1126/scitranslmed.aaf0968  1
2016 Hafner M, Niepel M, Chung M, Sorger PK. Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs. Nature Methods. PMID 27135972 DOI: 10.1038/nmeth.3853  1
2016 Tirosh I, Izar B, Prakadan SM, Wadsworth MH, Treacy D, Trombetta JJ, Rotem A, Rodman C, Lian C, Murphy G, Fallahi-Sichani M, Dutton-Regester K, Lin JR, Cohen O, Shah P, ... ... Sorger PK, et al. Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq. Science (New York, N.Y.). 352: 189-196. PMID 27124452 DOI: 10.1126/Science.Aad0501  1
2016 Hafner M, Niepel M, Duan Q, Paull E, Stuart J, Subramanian A, Ma’ayan A, Sorger PK. Abstract 788: Transcriptional landscape of drug response guides the design of potent and synergistic drug combinations Cancer Research. 76: 788-788. DOI: 10.1158/1538-7445.Am2016-788  1
2016 Mills C, Andrews D, Sorger P. Abstract 203: Single cell imaging of kinase inhibitor-induced effects in breast cancer cell lines Cancer Research. 76: 203-203. DOI: 10.1158/1538-7445.Am2016-203  1
2015 Lin JR, Fallahi-Sichani M, Sorger PK. Highly multiplexed imaging of single cells using a high-throughput cyclic immunofluorescence method. Nature Communications. 6: 8390. PMID 26399630 DOI: 10.1038/ncomms9390  1
2015 Roux J, Hafner M, Bandara S, Sims JJ, Hudson H, Chai D, Sorger PK. Fractional killing arises from cell-to-cell variability in overcoming a caspase activity threshold. Molecular Systems Biology. 11: 803. PMID 25953765  1
2015 Flusberg DA, Sorger PK. Surviving apoptosis: life-death signaling in single cells. Trends in Cell Biology. 25: 446-58. PMID 25920803 DOI: 10.1016/j.tcb.2015.03.003  1
2015 Fallahi-Sichani M, Moerke NJ, Niepel M, Zhang T, Gray NS, Sorger PK. Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis. Molecular Systems Biology. 11: 797. PMID 25814555 DOI: 10.15252/Msb.20145877  1
2015 Fallahi-Sichani M, Moerke NJ, Niepel M, Zhang T, Gray NS, Sorger PK. Systematic analysis of BRAFV 600E melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis Molecular Systems Biology. 11. DOI: 10.15252/msb.20145877  1
2015 Roux J, Hafner M, Bandara S, Sims JJ, Hudson H, Chai D, Sorger PK. Fractional killing arises from cell-to-cell variability in overcoming a caspase activity threshold Molecular Systems Biology. 11: 1-17. DOI: 10.15252/msb.20145584  1
2015 Albacker LA, Kohler R, Weissleder R, Sorger PK. Abstract PR07: The strength of drug selection determines the maximum fitness cost of resistance mutations in culture and xenografts Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-Pr07  1
2015 Hafner M, Niepel M, Duan Q, Lu X, Subramanian A, Ma'ayan A, Sorger PK. Abstract PR16: Transcriptional landscape of drug response guides the design of specific and potent drug combinations Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-Pr16  1
2015 Fallahi-Sichani M, Moerke NJ, Niepel M, Zhang T, Gray NS, Sorger PK. Abstract 3744: Single-cell analysis of adaptive resistance and fractional responses of melanoma cells to RAF/MEK inhibition Cancer Research. 75: 3744-3744. DOI: 10.1158/1538-7445.Am2015-3744  1
2015 Hafner M, Niepel M, Duan Q, Paull E, Stuart J, Subramanian A, Ma'ayan A, Sorger P. Abstract B20: Transcriptional landscape of drug response guides the design of specific and potent drug combinations Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-B20  1
2014 Gujral TS, Chan M, Peshkin L, Sorger PK, Kirschner MW, MacBeath G. A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis. Cell. 159: 844-56. PMID 25417160 DOI: 10.1016/J.Cell.2014.10.032  1
2014 AlQuraishi M, Koytiger G, Jenney A, MacBeath G, Sorger PK. A multiscale statistical mechanical framework integrates biophysical and genomic data to assemble cancer networks. Nature Genetics. 46: 1363-71. PMID 25362484 DOI: 10.1038/Ng.3138  1
2014 Foijer F, Xie SZ, Simon JE, Bakker PL, Conte N, Davis SH, Kregel E, Jonkers J, Bradley A, Sorger PK. Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress. Proceedings of the National Academy of Sciences of the United States of America. 111: 13427-32. PMID 25197064 DOI: 10.1073/pnas.1400892111  1
2014 Hyman BT, Sorger P. Failure analysis of clinical trials to test the amyloid hypothesis. Annals of Neurology. 76: 159-61. PMID 25044380 DOI: 10.1002/Ana.24227  1
2014 Duan Q, Flynn C, Niepel M, Hafner M, Muhlich JL, Fernandez NF, Rouillard AD, Tan CM, Chen EY, Golub TR, Sorger PK, Subramanian A, Ma'ayan A. LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures. Nucleic Acids Research. 42: W449-60. PMID 24906883 DOI: 10.1093/Nar/Gku476  1
2014 Niepel M, Hafner M, Pace EA, Chung M, Chai DH, Zhou L, Muhlich JL, Schoeberl B, Sorger PK. Analysis of growth factor signaling in genetically diverse breast cancer lines. Bmc Biology. 12: 20. PMID 24655548 DOI: 10.1186/1741-7007-12-20  1
2014 Kallenberger SM, Beaudouin J, Claus J, Fischer C, Sorger PK, Legewie S, Eils R. Intra- and interdimeric caspase-8 self-cleavage controls strength and timing of CD95-induced apoptosis. Science Signaling. 7: ra23. PMID 24619646 DOI: 10.1126/scisignal.2004738  1
2014 Fallahi-Sichani M, Honarnejad S, Heiser LM, Gray JW, Sorger PK. Abstract 5502: Metrics other than potency reveal systematic variation in responses to cancer drugs Cancer Research. 74: 5502-5502. DOI: 10.1158/1538-7445.Am2014-5502  1
2013 Koch Y, Wolf T, Sorger PK, Eils R, Brors B. Decision-tree based model analysis for efficient identification of parameter relations leading to different signaling states. Plos One. 8: e82593. PMID 24367526 DOI: 10.1371/journal.pone.0082593  1
2013 Sarosiek KA, Chi X, Bachman JA, Sims JJ, Montero J, Patel L, Flanagan A, Andrews DW, Sorger P, Letai A. BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response. Molecular Cell. 51: 751-65. PMID 24074954 DOI: 10.1016/J.Molcel.2013.08.048  1
2013 Niepel M, Hafner M, Pace EA, Chung M, Chai DH, Zhou L, Schoeberl B, Sorger PK. Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines. Science Signaling. 6: ra84. PMID 24065145 DOI: 10.1126/scisignal.2004379  1
2013 Fallahi-Sichani M, Honarnejad S, Heiser LM, Gray JW, Sorger PK. Metrics other than potency reveal systematic variation in responses to cancer drugs. Nature Chemical Biology. 9: 708-14. PMID 24013279 DOI: 10.1038/nchembio.1337  1
2013 Marco E, Dorn JF, Hsu PH, Jaqaman K, Sorger PK, Danuser G. S. cerevisiae chromosomes biorient via gradual resolution of syntely between S phase and anaphase. Cell. 154: 1127-39. PMID 23993100 DOI: 10.1016/J.Cell.2013.08.008  1
2013 Paull EO, Carlin DE, Niepel M, Sorger PK, Haussler D, Stuart JM. Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE). Bioinformatics (Oxford, England). 29: 2757-64. PMID 23986566 DOI: 10.1093/Bioinformatics/Btt471  1
2013 Flusberg DA, Sorger PK. Modulating cell-to-cell variability and sensitivity to death ligands by co-drugging. Physical Biology. 10: 035002. PMID 23735516 DOI: 10.1088/1478-3975/10/3/035002  1
2013 Flusberg DA, Roux J, Spencer SL, Sorger PK. Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes. Molecular Biology of the Cell. 24: 2186-200. PMID 23699397 DOI: 10.1091/mbc.E12-10-0737  1
2013 McAllister FE, Niepel M, Haas W, Huttlin E, Sorger PK, Gygi SP. Mass spectrometry based method to increase throughput for kinome analyses using ATP probes. Analytical Chemistry. 85: 4666-74. PMID 23607489 DOI: 10.1021/Ac303478G  1
2013 Lopez CF, Muhlich JL, Bachman JA, Sorger PK. Programming biological models in Python using PySB. Molecular Systems Biology. 9: 646. PMID 23423320 DOI: 10.1038/msb.2013.1  1
2013 Thurber GM, Yang KS, Reiner T, Kohler RH, Sorger P, Mitchison T, Weissleder R. Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo. Nature Communications. 4: 1504. PMID 23422672 DOI: 10.1038/Ncomms2506  1
2013 Eydgahi H, Chen WW, Muhlich JL, Vitkup D, Tsitsiklis JN, Sorger PK. Properties of cell death models calibrated and compared using Bayesian approaches. Molecular Systems Biology. 9: 644. PMID 23385484 DOI: 10.1038/Msb.2012.69  1
2013 Foijer F, DiTommaso T, Donati G, Hautaviita K, Xie SZ, Heath E, Smyth I, Watt FM, Sorger PK, Bradley A. Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 2928-33. PMID 23382243 DOI: 10.1073/pnas.1217388110  1
2013 Koytiger G, Kaushansky A, Gordus A, Rush J, Sorger PK, MacBeath G. Phosphotyrosine signaling proteins that drive oncogenesis tend to be highly interconnected. Molecular & Cellular Proteomics : McP. 12: 1204-13. PMID 23358503 DOI: 10.1074/Mcp.M112.025858  1
2013 Gujral TS, Karp RL, Finski A, Chan M, Schwartz PE, MacBeath G, Sorger P. Profiling phospho-signaling networks in breast cancer using reverse-phase protein arrays. Oncogene. 32: 3470-6. PMID 22945653 DOI: 10.1038/Onc.2012.378  1
2013 Bagci-Onder T, Agarwal A, Flusberg D, Wanningen S, Sorger P, Shah K. Real-time imaging of the dynamics of death receptors and therapeutics that overcome TRAIL resistance in tumors. Oncogene. 32: 2818-27. PMID 22824792 DOI: 10.1038/Onc.2012.304  1
2013 Fallahi-Sichani M, Moerke NJ, Dastur A, Benes CH, Sorger PK. Abstract 5213: A systems biology approach to understanding differential phenotypic outcome of BRAF(V600E) inhibition in melanoma cells. Cancer Research. 73: 5213-5213. DOI: 10.1158/1538-7445.Am2013-5213  1
2013 Sarosiek KA, Bachman J, Montero J, Patel L, Sims JJ, Chi X, Andrews DW, Sorger P, Letai A. Abstract 1713: BAX and BAK are preferentially activated by BIM and BID, respectively, affecting clinical chemotherapy response. Cancer Research. 73: 1713-1713. DOI: 10.1158/1538-7445.Am2013-1713  1
2013 Florian S, Chittajallu DR, Kohler RH, Orth JD, Sorger PK, Weissleder R, Danuser G, Mitchison TJ. Abstract A297: Microtubule targeting antimitotic drugs induce a lower mitotic arrest than clinically less effective antimitotic Eg5 inhibitors in mouse xenografts. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A297  1
2013 Schoeberl B, Pace E, Niepel M, Hafner M, Chai D, Sorger P. Abstract P6-05-01: Basal and induced receptor profiles cluster cell lines into subtypes and predict drug response in a panel of breast cancer lines Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P6-05-01  1
2012 Sorger PK, Schoeberl B. An expanding role for cell biologists in drug discovery and pharmacology. Molecular Biology of the Cell. 23: 4162-4. PMID 23112228 DOI: 10.1091/mbc.E12-05-0394  1
2012 Lee MJ, Ye AS, Gardino AK, Heijink AM, Sorger PK, MacBeath G, Yaffe MB. Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks. Cell. 149: 780-94. PMID 22579283 DOI: 10.1016/J.Cell.2012.03.031  1
2012 Gaudet S, Spencer SL, Chen WW, Sorger PK. Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis. Plos Computational Biology. 8: e1002482. PMID 22570596 DOI: 10.1371/Journal.Pcbi.1002482  1
2012 Kirouac DC, Saez-Rodriguez J, Swantek J, Burke JM, Lauffenburger DA, Sorger PK. Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks. Bmc Systems Biology. 6: 29. PMID 22548703 DOI: 10.1186/1752-0509-6-29  1
2012 Zhang T, Inesta-Vaquera F, Niepel M, Zhang J, Ficarro SB, Machleidt T, Xie T, Marto JA, Kim N, Sim T, Laughlin JD, Park H, LoGrasso PV, Patricelli M, Nomanbhoy TK, ... Sorger PK, et al. Discovery of potent and selective covalent inhibitors of JNK. Chemistry & Biology. 19: 140-54. PMID 22284361 DOI: 10.1016/J.Chembiol.2011.11.010  1
2012 Luckert K, Gujral TS, Chan M, Sevecka M, Joos TO, Sorger PK, Macbeath G, Pötz O. A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins. Science Signaling. 5: pl1. PMID 22234610 DOI: 10.1126/Scisignal.2002372  1
2012 Liu Q, Kirubakaran S, Hur W, Niepel M, Westover K, Thoreen CC, Wang J, Ni J, Patricelli MP, Vogel K, Riddle S, Waller DL, Traynor R, Sanda T, Zhao Z, ... ... Sorger PK, et al. Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics. The Journal of Biological Chemistry. 287: 9742-52. PMID 22223645 DOI: 10.1074/Jbc.M111.304485  1
2012 Luckert K, Gujral TS, Chan M, Sevecka M, Joos TO, Sorger PK, MacBeath G, Pötz O. A correction to the protocol titled: "A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins" by K. Luckert, T. S. Gujral, M. Chan, T. O. Joos, P. K. Sorger, G. MacBeath, O. Pötz Science Signaling. 5. DOI: 10.1126/scisignal.5238er5  1
2011 Aldridge BB, Gaudet S, Lauffenburger DA, Sorger PK. Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis. Molecular Systems Biology. 7: 553. PMID 22108795 DOI: 10.1038/msb.2011.85  1
2011 Hagan RS, Manak MS, Buch HK, Meier MG, Meraldi P, Shah JV, Sorger PK. p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment. Molecular Biology of the Cell. 22: 4236-46. PMID 21965286 DOI: 10.1091/Mbc.E11-03-0216  1
2011 Prill RJ, Saez-Rodriguez J, Alexopoulos LG, Sorger PK, Stolovitzky G. Crowdsourcing network inference: the DREAM predictive signaling network challenge. Science Signaling. 4: mr7. PMID 21900204 DOI: 10.1126/Scisignal.2002212  1
2011 Kleiman LB, Maiwald T, Conzelmann H, Lauffenburger DA, Sorger PK. Rapid phospho-turnover by receptor tyrosine kinases impacts downstream signaling and drug binding. Molecular Cell. 43: 723-37. PMID 21884975 DOI: 10.1016/j.molcel.2011.07.014  1
2011 Rines DR, Thomann D, Dorn JF, Goodwin P, Sorger PK. Live cell imaging of yeast. Cold Spring Harbor Protocols. 2011. PMID 21880825 DOI: 10.1101/pdb.top065482  1
2011 Saez-Rodriguez J, Alexopoulos LG, Zhang M, Morris MK, Lauffenburger DA, Sorger PK. Comparing signaling networks between normal and transformed hepatocytes using discrete logical models. Cancer Research. 71: 5400-11. PMID 21742771 DOI: 10.1158/0008-5472.Can-10-4453  1
2011 Orth JD, Kohler RH, Foijer F, Sorger PK, Weissleder R, Mitchison TJ. Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics. Cancer Research. 71: 4608-16. PMID 21712408 DOI: 10.1158/0008-5472.Can-11-0412  1
2011 Hached K, Xie SZ, Buffin E, Cladière D, Rachez C, Sacras M, Sorger PK, Wassmann K. Mps1 at kinetochores is essential for female mouse meiosis I. Development (Cambridge, England). 138: 2261-71. PMID 21558374 DOI: 10.1242/dev.061317  1
2011 Millard BL, Niepel M, Menden MP, Muhlich JL, Sorger PK. Adaptive informatics for multifactorial and high-content biological data. Nature Methods. 8: 487-93. PMID 21516115 DOI: 10.1038/nmeth.1600  1
2011 Spencer SL, Sorger PK. Measuring and modeling apoptosis in single cells. Cell. 144: 926-39. PMID 21414484 DOI: 10.1016/j.cell.2011.03.002  1
2011 Morris MK, Saez-Rodriguez J, Clarke DC, Sorger PK, Lauffenburger DA. Training signaling pathway maps to biochemical data with constrained fuzzy logic: quantitative analysis of liver cell responses to inflammatory stimuli. Plos Computational Biology. 7: e1001099. PMID 21408212 DOI: 10.1371/Journal.Pcbi.1001099  1
2011 Luckert K, Götschel F, Sorger PK, Hecht A, Joos TO, Pötz O. Snapshots of protein dynamics and post-translational modifications in one experiment--beta-catenin and its functions. Molecular & Cellular Proteomics : McP. 10: M110.007377. PMID 21378377 DOI: 10.1074/mcp.M110.007377  1
2011 Bachman JA, Sorger P. New approaches to modeling complex biochemistry. Nature Methods. 8: 130-1. PMID 21278724 DOI: 10.1038/Nmeth0211-130  1
2010 Cho US, Corbett KD, Al-Bassam J, Bellizzi JJ, De Wulf P, Espelin CW, Miranda JJ, Simons K, Wei RR, Sorger PK, Harrison SC. Molecular structures and interactions in the yeast kinetochore. Cold Spring Harbor Symposia On Quantitative Biology. 75: 395-401. PMID 21467141 DOI: 10.1101/Sqb.2010.75.040  1
2010 Chen WW, Niepel M, Sorger PK. Classic and contemporary approaches to modeling biochemical reactions. Genes & Development. 24: 1861-75. PMID 20810646 DOI: 10.1101/Gad.1945410  1
2010 Espelin CW, Goldsipe A, Sorger PK, Lauffenburger DA, de Graaf D, Hendriks BS. Elevated GM-CSF and IL-1beta levels compromise the ability of p38 MAPK inhibitors to modulate TNFalpha levels in the human monocytic/macrophage U937 cell line. Molecular Biosystems. 6: 1956-72. PMID 20617251 DOI: 10.1039/c002848g  1
2010 Yang R, Niepel M, Mitchison TK, Sorger PK. Dissecting variability in responses to cancer chemotherapy through systems pharmacology. Clinical Pharmacology and Therapeutics. 88: 34-8. PMID 20520606 DOI: 10.1038/clpt.2010.96  1
2010 Alexopoulos LG, Saez-Rodriguez J, Cosgrove BD, Lauffenburger DA, Sorger PK. Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes. Molecular & Cellular Proteomics : McP. 9: 1849-65. PMID 20460255 DOI: 10.1074/Mcp.M110.000406  1
2010 Kim KA, Spencer SL, Albeck JG, Burke JM, Sorger PK, Gaudet S, Kim do H. Systematic calibration of a cell signaling network model. Bmc Bioinformatics. 11: 202. PMID 20416044 DOI: 10.1186/1471-2105-11-202  1
2010 Lazzara MJ, Lane K, Chan R, Jasper PJ, Yaffe MB, Sorger PK, Jacks T, Neel BG, Lauffenburger DA. Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor-activating mutations. Cancer Research. 70: 3843-50. PMID 20406974 DOI: 10.1158/0008-5472.Can-09-3421  1
2010 Cosgrove BD, Alexopoulos LG, Hang TC, Hendriks BS, Sorger PK, Griffith LG, Lauffenburger DA. Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation. Molecular Biosystems. 6: 1195-206. PMID 20361094 DOI: 10.1039/B926287C  1
2010 Morris MK, Saez-Rodriguez J, Sorger PK, Lauffenburger DA. Logic-based models for the analysis of cell signaling networks. Biochemistry. 49: 3216-24. PMID 20225868 DOI: 10.1021/Bi902202Q  1
2010 Prill RJ, Marbach D, Saez-Rodriguez J, Sorger PK, Alexopoulos LG, Xue X, Clarke ND, Altan-Bonnet G, Stolovitzky G. Towards a rigorous assessment of systems biology models: the DREAM3 challenges. Plos One. 5: e9202. PMID 20186320 DOI: 10.1371/Journal.Pone.0009202  1
2010 Sorger P, Spencer S, Gaudet S, Aldridge B, D F. Abstract ES6-2: Cell to Cell Variability in the Responses of Tumor Cells to Death Ligands and Other Anti-Cancer Drugs Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-Es6-2  1
2009 Saez-Rodriguez J, Alexopoulos LG, Epperlein J, Samaga R, Lauffenburger DA, Klamt S, Sorger PK. Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction. Molecular Systems Biology. 5: 331. PMID 19953085 DOI: 10.1038/Msb.2009.87  1
2009 Pagliuca C, Draviam VM, Marco E, Sorger PK, De Wulf P. Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint. Plos One. 4: e7640. PMID 19893618 DOI: 10.1371/journal.pone.0007640  1
2009 Niepel M, Spencer SL, Sorger PK. Non-genetic cell-to-cell variability and the consequences for pharmacology. Current Opinion in Chemical Biology. 13: 556-61. PMID 19833543 DOI: 10.1016/j.cbpa.2009.09.015  1
2009 Samaga R, Saez-Rodriguez J, Alexopoulos LG, Sorger PK, Klamt S. The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data. Plos Computational Biology. 5: e1000438. PMID 19662154 DOI: 10.1371/Journal.Pcbi.1000438  1
2009 Aebersold R, Auffray C, Baney E, Barillot E, Brazma A, Brett C, Brunak S, Butte A, Califano A, Celis J, Cufer T, Ferrell J, Galas D, Gallahan D, Gatenby R, ... ... Sorger P, et al. Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008). Molecular Oncology. 3: 9-17. PMID 19383362 DOI: 10.1016/J.Molonc.2008.11.003  1
2009 Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK. Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature. 459: 428-32. PMID 19363473 DOI: 10.1038/nature08012  1
2009 Cosgrove BD, King BM, Hasan MA, Alexopoulos LG, Farazi PA, Hendriks BS, Griffith LG, Sorger PK, Tidor B, Xu JJ, Lauffenburger DA. Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity. Toxicology and Applied Pharmacology. 237: 317-30. PMID 19362101 DOI: 10.1016/J.Taap.2009.04.002  1
2009 Aldridge BB, Saez-Rodriguez J, Muhlich JL, Sorger PK, Lauffenburger DA. Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling. Plos Computational Biology. 5: e1000340. PMID 19343194 DOI: 10.1371/Journal.Pcbi.1000340  1
2009 Chen WW, Schoeberl B, Jasper PJ, Niepel M, Nielsen UB, Lauffenburger DA, Sorger PK. Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data. Molecular Systems Biology. 5: 239. PMID 19156131 DOI: 10.1038/Msb.2008.74  1
2009 McAinsh AD, Meraldi P, Draviam VM, Toso A, Sorger PK. The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation (The EMBO Journal (2006) 25 (4033-4049) DOI:10.1038/sj.emboj.7601293) Embo Journal. 28: 1374. DOI: 10.1038/emboj.2009.94  1
2009 Lopez CF, Fire E, Keating A, Sorger PK. Modeling Extrinsic Apoptosis Regulatory Network Pathways Using A Rules-based Framework Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.1516  1
2008 Sorger PK. Microfluidics closes in on point-of-care assays. Nature Biotechnology. 26: 1345-6. PMID 19060870 DOI: 10.1038/nbt1208-1345  1
2008 Albeck JG, Burke JM, Spencer SL, Lauffenburger DA, Sorger PK. Modeling a snap-action, variable-delay switch controlling extrinsic cell death. Plos Biology. 6: 2831-52. PMID 19053173 DOI: 10.1371/journal.pbio.0060299  1
2008 Foijer F, Draviam VM, Sorger PK. Studying chromosome instability in the mouse. Biochimica Et Biophysica Acta. 1786: 73-82. PMID 18706976 DOI: 10.1016/j.bbcan.2008.07.004  1
2008 Cohen RL, Espelin CW, De Wulf P, Sorger PK, Harrison SC, Simons KT. Structural and functional dissection of Mif2p, a conserved DNA-binding kinetochore protein. Molecular Biology of the Cell. 19: 4480-91. PMID 18701705 DOI: 10.1091/Mbc.E08-03-0297  1
2008 Albeck JG, Burke JM, Aldridge BB, Zhang M, Lauffenburger DA, Sorger PK. Quantitative analysis of pathways controlling extrinsic apoptosis in single cells. Molecular Cell. 30: 11-25. PMID 18406323 DOI: 10.1016/j.molcel.2008.02.012  1
2008 Saez-Rodriguez J, Goldsipe A, Muhlich J, Alexopoulos LG, Millard B, Lauffenburger DA, Sorger PK. Flexible informatics for linking experimental data to mathematical models via DataRail. Bioinformatics (Oxford, England). 24: 840-7. PMID 18218655 DOI: 10.1093/Bioinformatics/Btn018  1
2008 Foijer F, Simonis M, van Vliet M, Wessels L, Kerkhoven R, Sorger PK, Te Riele H. Oncogenic pathways impinging on the G2-restriction point. Oncogene. 27: 1142-54. PMID 17700522 DOI: 10.1038/sj.onc.1210724  1
2008 Alexopoulos LG, Lauffenburger DA, Sorger PK. Modeling pro-death signaling pathways in cancer hepatocytes using multi-combinatorial treatments of inhibitors and stimuli 8th Ieee International Conference On Bioinformatics and Bioengineering, Bibe 2008. DOI: 10.1109/BIBE.2008.4696732  1
2007 Niault T, Hached K, Sotillo R, Sorger PK, Maro B, Benezra R, Wassmann K. Changing Mad2 levels affects chromosome segregation and spindle assembly checkpoint control in female mouse meiosis I. Plos One. 2: e1165. PMID 18043727 DOI: 10.1371/Journal.Pone.0001165  1
2007 Bellizzi JJ, Sorger PK, Harrison SC. Crystal structure of the yeast inner kinetochore subunit Cep3p. Structure (London, England : 1993). 15: 1422-30. PMID 17997968 DOI: 10.1016/J.Str.2007.09.008  1
2007 Jaqaman K, Dorn JF, Marco E, Sorger PK, Danuser G. Phenotypic clustering of yeast mutants based on kinetochore microtubule dynamics. Bioinformatics (Oxford, England). 23: 1666-73. PMID 17483508 DOI: 10.1093/Bioinformatics/Btm230  1
2007 Stegmeier F, Rape M, Draviam VM, Nalepa G, Sowa ME, Ang XL, McDonald ER, Li MZ, Hannon GJ, Sorger PK, Kirschner MW, Harper JW, Elledge SJ. Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities. Nature. 446: 876-81. PMID 17443180 DOI: 10.1038/Nature05694  1
2007 Draviam VM, Stegmeier F, Nalepa G, Sowa ME, Chen J, Liang A, Hannon GJ, Sorger PK, Harper JW, Elledge SJ. A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling. Nature Cell Biology. 9: 556-64. PMID 17417629 DOI: 10.1038/Ncb1569  1
2007 Stegmeier F, Rape M, Draviam VM, Nalepa G, Sowa ME, Ang XL, McDonald ER, Li MZ, Hannon GJ, Sorger PK, Kirschner MW, Harper JW, Elledge SJ. Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities Nature. 447: 876-881.  1
2006 Schoeberl B, Pace E, Howard S, Garantcharova V, Kudla A, Sorger PK, Nielsen UB. A data-driven computational model of the ErbB receptor signaling network. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 53-4. PMID 17946779 DOI: 10.1109/IEMBS.2006.259754  1
2006 Aldridge BB, Haller G, Sorger PK, Lauffenburger DA. Direct Lyapunov exponent analysis enables parametric study of transient signalling governing cell behaviour. Systems Biology. 153: 425-32. PMID 17186704 DOI: 10.1049/ip-syb:20050065  1
2006 Aldridge BB, Burke JM, Lauffenburger DA, Sorger PK. Physicochemical modelling of cell signalling pathways. Nature Cell Biology. 8: 1195-203. PMID 17060902 DOI: 10.1038/ncb1497  1
2006 Albeck JG, MacBeath G, White FM, Sorger PK, Lauffenburger DA, Gaudet S. Collecting and organizing systematic sets of protein data. Nature Reviews. Molecular Cell Biology. 7: 803-12. PMID 17057751 DOI: 10.1038/Nrm2042  1
2006 Jaqaman K, Dorn JF, Jelson GS, Tytell JD, Sorger PK, Danuser G. Comparative autoregressive moving average analysis of kinetochore microtubule dynamics in yeast. Biophysical Journal. 91: 2312-25. PMID 16940476 DOI: 10.1529/Biophysj.106.080333  1
2006 McAinsh AD, Meraldi P, Draviam VM, Toso A, Sorger PK. The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation. The Embo Journal. 25: 4033-49. PMID 16932742 DOI: 10.1038/Sj.Emboj.7601293  1
2006 Fitzgerald JB, Schoeberl B, Nielsen UB, Sorger PK. Systems biology and combination therapy in the quest for clinical efficacy. Nature Chemical Biology. 2: 458-66. PMID 16921358 DOI: 10.1038/nchembio817  1
2006 El-Ali J, Sorger PK, Jensen KF. Cells on chips. Nature. 442: 403-11. PMID 16871208 DOI: 10.1038/nature05063  1
2006 Wei RR, Schnell JR, Larsen NA, Sorger PK, Chou JJ, Harrison SC. Structure of a central component of the yeast kinetochore: the Spc24p/Spc25p globular domain. Structure (London, England : 1993). 14: 1003-9. PMID 16765893 DOI: 10.1016/J.Str.2006.04.007  1
2006 Draviam VM, Shapiro I, Aldridge B, Sorger PK. Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells. The Embo Journal. 25: 2814-27. PMID 16763565 DOI: 10.1038/sj.emboj.7601168  1
2006 Janes KA, Gaudet S, Albeck JG, Nielsen UB, Lauffenburger DA, Sorger PK. The response of human epithelial cells to TNF involves an inducible autocrine cascade. Cell. 124: 1225-39. PMID 16564013 DOI: 10.1016/j.cell.2006.01.041  1
2006 Meraldi P, McAinsh AD, Rheinbay E, Sorger PK. Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins. Genome Biology. 7: R23. PMID 16563186 DOI: 10.1186/Gb-2006-7-3-R23  1
2006 Tytell JD, Sorger PK. Analysis of kinesin motor function at budding yeast kinetochores. The Journal of Cell Biology. 172: 861-74. PMID 16533946 DOI: 10.1083/jcb.200509101  1
2005 Janes KA, Albeck JG, Gaudet S, Sorger PK, Lauffenburger DA, Yaffe MB. A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis. Science (New York, N.Y.). 310: 1646-53. PMID 16339439 DOI: 10.1126/Science.1116598  1
2005 Dorn JF, Jaqaman K, Rines DR, Jelson GS, Sorger PK, Danuser G. Yeast kinetochore microtubule dynamics analyzed by high-resolution three-dimensional microscopy. Biophysical Journal. 89: 2835-54. PMID 16192284 DOI: 10.1529/Biophysj.104.058461  1
2005 Burds AA, Lutum AS, Sorger PK. Generating chromosome instability through the simultaneous deletion of Mad2 and p53. Proceedings of the National Academy of Sciences of the United States of America. 102: 11296-301. PMID 16055552 DOI: 10.1073/pnas.0505053102  1
2005 Gaudet S, Janes KA, Albeck JG, Pace EA, Lauffenburger DA, Sorger PK. A compendium of signals and responses triggered by prodeath and prosurvival cytokines. Molecular & Cellular Proteomics : McP. 4: 1569-90. PMID 16030008 DOI: 10.1074/mcp.M500158-MCP200  1
2005 Meraldi P, Sorger PK. A dual role for Bub1 in the spindle checkpoint and chromosome congression. The Embo Journal. 24: 1621-33. PMID 15933723 DOI: 10.1038/Sj.Emboj.7600641  1
2005 El-Ali J, Gaudet S, Günther A, Sorger PK, Jensen KF. Cell stimulus and lysis in a microfluidic device with segmented gas-liquid flow. Analytical Chemistry. 77: 3629-36. PMID 15924398 DOI: 10.1021/ac050008x  1
2005 Goldberg IG, Allan C, Burel JM, Creager D, Falconi A, Hochheiser H, Johnston J, Mellen J, Sorger PK, Swedlow JR. The Open Microscopy Environment (OME) Data Model and XML file: open tools for informatics and quantitative analysis in biological imaging. Genome Biology. 6: R47. PMID 15892875 DOI: 10.1186/Gb-2005-6-5-R47  1
2005 Wei RR, Sorger PK, Harrison SC. Molecular organization of the Ndc80 complex, an essential kinetochore component. Proceedings of the National Academy of Sciences of the United States of America. 102: 5363-7. PMID 15809444 DOI: 10.1073/Pnas.0501168102  1
2005 Hagan RS, Sorger PK. Cell biology: the more MAD, the merrier. Nature. 434: 575-7. PMID 15800607 DOI: 10.1038/434575a  1
2005 Sorger PK. A reductionist's systems biology: opinion. Current Opinion in Cell Biology. 17: 9-11. PMID 15661513 DOI: 10.1016/j.ceb.2004.12.012  1
2005 Miranda JJ, De Wulf P, Sorger PK, Harrison SC. The yeast DASH complex forms closed rings on microtubules. Nature Structural & Molecular Biology. 12: 138-43. PMID 15640796 DOI: 10.1038/Nsmb896  1
2005 Lazzara MJ, Jasper P, Sorger P, Lauffenburger DA. Altered Egfr trafficking and signaling in iressa-sensitive human cell lines Aiche Annual Meeting, Conference Proceedings. 9238.  1
2004 Janes KA, Kelly JR, Gaudet S, Albeck JG, Sorger PK, Lauffenburger DA. Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 11: 544-61. PMID 15579231 DOI: 10.1089/1066527041887258  1
2004 Meraldi P, Draviam VM, Sorger PK. Timing and checkpoints in the regulation of mitotic progression. Developmental Cell. 7: 45-60. PMID 15239953 DOI: 10.1016/J.Devcel.2004.06.006  1
2004 Draviam VM, Xie S, Sorger PK. Chromosome segregation and genomic stability. Current Opinion in Genetics & Development. 14: 120-5. PMID 15196457 DOI: 10.1016/j.gde.2004.02.007  1
2004 Gillett ES, Espelin CW, Sorger PK. Spindle checkpoint proteins and chromosome-microtubule attachment in budding yeast. The Journal of Cell Biology. 164: 535-46. PMID 14769859 DOI: 10.1083/jcb.200308100  1
2003 De Wulf P, McAinsh AD, Sorger PK. Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. Genes & Development. 17: 2902-21. PMID 14633972 DOI: 10.1101/Gad.1144403  1
2003 McAinsh AD, Tytell JD, Sorger PK. Structure, function, and regulation of budding yeast kinetochores. Annual Review of Cell and Developmental Biology. 19: 519-39. PMID 14570580 DOI: 10.1146/Annurev.Cellbio.19.111301.155607  1
2003 Espelin CW, Simons KT, Harrison SC, Sorger PK. Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Molecular Biology of the Cell. 14: 4557-68. PMID 13679521 DOI: 10.1091/Mbc.E02-08-0533  1
2003 Thomann D, Dorn J, Sorger PK, Danuser G. Automatic fluorescent tag localization II: Improvement in super-resolution by relative tracking. Journal of Microscopy. 211: 230-48. PMID 12950472 DOI: 10.1046/J.1365-2818.2003.01223.X  1
2003 Nielsen UB, Cardone MH, Sinskey AJ, MacBeath G, Sorger PK. Profiling receptor tyrosine kinase activation by using Ab microarrays. Proceedings of the National Academy of Sciences of the United States of America. 100: 9330-5. PMID 12876202 DOI: 10.1073/Pnas.1633513100  1
2003 Janes KA, Albeck JG, Peng LX, Sorger PK, Lauffenburger DA, Yaffe MB. A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: application to sepsis-apoptosis. Molecular & Cellular Proteomics : McP. 2: 463-73. PMID 12832460 DOI: 10.1074/Mcp.M300045-Mcp200  1
2003 Swedlow JR, Goldberg I, Brauner E, Sorger PK. Informatics and quantitative analysis in biological imaging. Science (New York, N.Y.). 300: 100-2. PMID 12677061 DOI: 10.1126/science.1082602  1
2002 Fritz J, Cooper EB, Gaudet S, Sorger PK, Manalis SR. Electronic detection of DNA by its intrinsic molecular charge. Proceedings of the National Academy of Sciences of the United States of America. 99: 14142-6. PMID 12386345 DOI: 10.1073/pnas.232276699  1
2002 Thomann D, Rines DR, Sorger PK, Danuser G. Automatic fluorescent tag detection in 3D with super-resolution: application to the analysis of chromosome movement. Journal of Microscopy. 208: 49-64. PMID 12366597 DOI: 10.1046/J.1365-2818.2002.01066.X  1
2002 Sachs K, Gifford D, Jaakkola T, Sorger P, Lauffenburger DA. Bayesian network approach to cell signaling pathway modeling. Science's Stke : Signal Transduction Knowledge Environment. 2002: pe38. PMID 12209052 DOI: 10.1126/Stke.2002.148.Pe38  1
2002 Rines DR, He X, Sorger PK. Quantitative microscopy of green fluorescent protein-labeled yeast. Methods in Enzymology. 351: 16-34. PMID 12073342 DOI: 10.1016/S0076-6879(02)51839-5  1
2001 Gillett ES, Sorger PK. Tracing the pathway of spindle assembly checkpoint signaling. Developmental Cell. 1: 162-4. PMID 11702776 DOI: 10.1016/S1534-5807(01)00032-6  1
2001 He X, Rines DR, Espelin CW, Sorger PK. Molecular analysis of kinetochore-microtubule attachment in budding yeast. Cell. 106: 195-206. PMID 11511347 DOI: 10.1016/S0092-8674(01)00438-X  1
2001 Brown CS, Goodwin PC, Sorger PK. Image metrics in the statistical analysis of DNA microarray data. Proceedings of the National Academy of Sciences of the United States of America. 98: 8944-9. PMID 11481466 DOI: 10.1073/pnas.161242998  1
2001 Kaplan KB, Burds AA, Swedlow JR, Bekir SS, Sorger PK, Näthke IS. A role for the Adenomatous Polyposis Coli protein in chromosome segregation. Nature Cell Biology. 3: 429-32. PMID 11283619 DOI: 10.1038/35070123  1
2001 Michel LS, Liberal V, Chatterjee A, Kirchwegger R, Pasche B, Gerald W, Dobles M, Sorger PK, Murty VV, Benezra R. MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells. Nature. 409: 355-9. PMID 11201745 DOI: 10.1038/35053094  1
2000 Dobles M, Sorger PK. Mitotic checkpoints, genetic instability, and cancer. Cold Spring Harbor Symposia On Quantitative Biology. 65: 361-8. PMID 12760051  1
2000 He X, Asthana S, Sorger PK. Transient sister chromatid separation and elastic deformation of chromosomes during mitosis in budding yeast. Cell. 101: 763-75. PMID 10892747  1
2000 Dobles M, Liberal V, Scott ML, Benezra R, Sorger PK. Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2. Cell. 101: 635-45. PMID 10892650 DOI: 10.1016/S0092-8674(00)80875-2  1
1999 Norman TC, Smith DL, Sorger PK, Drees BL, O'Rourke SM, Hughes TR, Roberts CJ, Friend SH, Fields S, Murray AW. Genetic selection of peptide inhibitors of biological pathways. Science (New York, N.Y.). 285: 591-5. PMID 10417390 DOI: 10.1126/Science.285.5427.591  1
1999 Martinez-Exposito MJ, Kaplan KB, Copeland J, Sorger PK. Retention of the BUB3 checkpoint protein on lagging chromosomes. Proceedings of the National Academy of Sciences of the United States of America. 96: 8493-8. PMID 10411903 DOI: 10.1073/Pnas.96.15.8493  1
1999 Russell ID, Grancell AS, Sorger PK. The unstable F-box protein p58-Ctf13 forms the structural core of the CBF3 kinetochore complex. The Journal of Cell Biology. 145: 933-50. PMID 10352012 DOI: 10.1083/jcb.145.5.933  1
1999 Sassoon I, Severin FF, Andrews PD, Taba MR, Kaplan KB, Ashford AJ, Stark MJ, Sorger PK, Hyman AA. Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p. Genes & Development. 13: 545-55. PMID 10072383 DOI: 10.1101/Gad.13.5.545  1
1999 Severin F, Kaplan K, Sorger P, Hyman T. In vitro assays for studying Saccharomyces cerevisiae kinetochore activity. Methods in Cell Biology. 61: 145-53. PMID 9891313 DOI: 10.1016/S0091-679X(08)61979-2  1
1999 Bender P, Beyer D, Brück-Binninger U, Kowallek R, Schmidt S, Sorger P, Wielpütz H, Wittmann EC. Überlegungen zur fachmathematischen Ausbildung der angehenden Grundschullehrerinnen und -lehrer: Gekürzte Fassung eines für das Ministerium für Schule und Weiterbildung des Landes Nordrhein-Westfalen (NW) 1996 entwickelten und in Bardy (1997) abgedruckten Papiers Journal Fur Mathematik-Didaktik. 20: 301-310. DOI: 10.1007/BF03338903  1
1998 Grancell A, Sorger PK. Chromosome movement: kinetochores motor along. Current Biology : Cb. 8: R382-5. PMID 9635184  1
1998 Wiens GR, Sorger PK. Centromeric chromatin and epigenetic effects in kinetochore assembly. Cell. 93: 313-6. PMID 9590163 DOI: 10.1016/S0092-8674(00)81157-5  1
1997 Sorger PK, Dobles M, Tournebize R, Hyman AA. Coupling cell division and cell death to microtubule dynamics. Current Opinion in Cell Biology. 9: 807-14. PMID 9425345 DOI: 10.1016/S0955-0674(97)80081-6  1
1997 Espelin CW, Kaplan KB, Sorger PK. Probing the architecture of a simple kinetochore using DNA-protein crosslinking. The Journal of Cell Biology. 139: 1383-96. PMID 9396745 DOI: 10.1083/Jcb.139.6.1383  1
1997 Kaplan KB, Hyman AA, Sorger PK. Regulating the yeast kinetochore by ubiquitin-dependent degradation and Skp1p-mediated phosphorylation. Cell. 91: 491-500. PMID 9390558 DOI: 10.1016/S0092-8674(00)80435-3  1
1997 Severin FF, Sorger PK, Hyman AA. Kinetochores distinguish GTP from GDP forms of the microtubule lattice. Nature. 388: 888-91. PMID 9278051 DOI: 10.1038/42270  1
1995 Hyman AA, Sorger PK. Structure and function of kinetochores in budding yeast. Annual Review of Cell and Developmental Biology. 11: 471-95. PMID 8689566 DOI: 10.1146/annurev.cb.11.110195.002351  1
1995 Sorger PK, Doheny KF, Hieter P, Kopski KM, Huffaker TC, Hyman AA. Two genes required for the binding of an essential Saccharomyces cerevisiae kinetochore complex to DNA. Proceedings of the National Academy of Sciences of the United States of America. 92: 12026-30. PMID 8618837 DOI: 10.1073/Pnas.92.26.12026  1
1994 Sorger PK, Severin FF, Hyman AA. Factors required for the binding of reassembled yeast kinetochores to microtubules in vitro. The Journal of Cell Biology. 127: 995-1008. PMID 7962081 DOI: 10.1083/jcb.127.4.995  1
1993 Doheny KF, Sorger PK, Hyman AA, Tugendreich S, Spencer F, Hieter P. Identification of essential components of the S. cerevisiae kinetochore. Cell. 73: 761-74. PMID 8500169 DOI: 10.1016/0092-8674(93)90255-O  1
1992 Sorger PK, Murray AW. S-phase feedback control in budding yeast independent of tyrosine phosphorylation of p34cdc28. Nature. 355: 365-8. PMID 1731250 DOI: 10.1038/355365A0  1
1991 Sorger PK. Heat shock factor and the heat shock response. Cell. 65: 363-6. PMID 2018972 DOI: 10.1016/0092-8674(91)90452-5  1
1990 Sorger PK. Yeast heat shock factor contains separable transient and sustained response transcriptional activators. Cell. 62: 793-805. PMID 2201452 DOI: 10.1016/0092-8674(90)90123-V  1
1989 Sorger PK, Nelson HC. Trimerization of a yeast transcriptional activator via a coiled-coil motif. Cell. 59: 807-13. PMID 2686840 DOI: 10.1016/0092-8674(89)90604-1  1
1988 Sorger PK, Pelham HR. Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation. Cell. 54: 855-64. PMID 3044613 DOI: 10.1016/S0092-8674(88)91219-6  1
1987 Sorger PK, Pelham HR. The glucose-regulated protein grp94 is related to heat shock protein hsp90. Journal of Molecular Biology. 194: 341-4. PMID 3612810 DOI: 10.1016/0022-2836(87)90380-9  1
1987 Sorger PK, Pelham HR. Cloning and expression of a gene encoding hsc73, the major hsp70-like protein in unstressed rat cells. The Embo Journal. 6: 993-8. PMID 3595567  1
1987 Sorger PK, Pelham HR. Purification and characterization of a heat-shock element binding protein from yeast. The Embo Journal. 6: 3035-41. PMID 3319580  1
1987 Sorger PK, Lewis MJ, Pelham HR. Heat shock factor is regulated differently in yeast and HeLa cells. Nature. 329: 81-4. PMID 3306402 DOI: 10.1038/329081a0  1
1986 Sorger PK, Stockley PG, Harrison SC. Structure and assembly of turnip crinkle virus. II. Mechanism of reassembly in vitro. Journal of Molecular Biology. 191: 639-58. PMID 3806677 DOI: 10.1016/0022-2836(86)90451-1  1
1986 Sorger PK, Crowther RA, Finch JT, Pearse BM. Clathrin cubes: an extreme variant of the normal cage. The Journal of Cell Biology. 103: 1213-9. PMID 3771632  1
1986 Weston K, Cozens A, Nelson HCM, Fairall L, Amos L, Mengle-Gaw L, Lefebvre FA, Clark MJ, Kenyon C, Bienz M, Breeden L, Schnabel H, Robinson M, Albertson D, Greenwald I, ... ... Sorger P, et al. Sexist ads Nature. 321: 106. DOI: 10.1038/321106b0  1
1969 Kirchgässner K, Sorger P. Branching analysis for the taylor problem Quarterly Journal of Mechanics and Applied Mathematics. 22: 183-209. DOI: 10.1093/qjmam/22.2.183  1
1966 Sorger P. Über ein Variationsproblem aus der nichtlinearen Stabilitätstheorie zäher, inkompressibler Strömungen Zeitschrift FüR Angewandte Mathematik Und Physik Zamp. 17: 201-226. DOI: 10.1007/BF01601387  1
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