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Joshua W. Little, Ph.D. - Publications

Affiliations: 
2011 Anatomy Saint Louis University, St. Louis, MO, United States 
Area:
Neuroscience Biology, Behavioral Sciences Psychology, Pharmacology
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Syrett M, Reed NR, Reed WR, Richey ML, Frolov A, Little JW. Sex-Related Pain Behavioral Differences following Unilateral NGF Injections in a Rat Model of Low Back Pain. Biology. 11. PMID 35741445 DOI: 10.3390/biology11060924  0.312
2020 Reed WR, Little JW, Lima CR, Sorge RE, Yarar-Fisher C, Eraslan M, Hurt CP, Ness TJ, Gu JG, Martins DF, Li P. Spinal Mobilization Prevents NGF-Induced Trunk Mechanical Hyperalgesia and Attenuates Expression of CGRP. Frontiers in Neuroscience. 14: 385. PMID 32425750 DOI: 10.3389/Fnins.2020.00385  0.506
2018 Stockstill K, Doyle TM, Yan X, Chen Z, Janes K, Little JW, Braden K, Lauro F, Giancotti LA, Harada CM, Yadav R, Xiao WH, Lionberger JM, Neumann WL, Bennett GJ, et al. Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic pain. The Journal of Experimental Medicine. PMID 29703731 DOI: 10.1084/Jem.20170584  0.746
2018 Touchette JC, Little JW, Wilken GH, Salvemini D, Macarthur H. The neurotoxin DSP-4 induces hyperalgesia in rats that is accompanied by spinal oxidative stress and cytokine production. Neuroscience. PMID 29421433 DOI: 10.1016/J.Neuroscience.2018.01.058  0.596
2018 Wahlman C, Doyle TM, Little JW, Luongo L, Janes K, Chen Z, Esposito E, Tosh DK, Cuzzocrea S, Jacobson KA, Salvemini D. Chemotherapy-induced pain is promoted by enhanced spinal adenosine kinase levels via astrocyte-dependent mechanisms. Pain. PMID 29419652 DOI: 10.1097/J.Pain.0000000000001177  0.721
2017 Reed WR, Cranston JT, Onifer SM, Little JW, Sozio RS. Decreased spontaneous activity and altered evoked nociceptive response of rat thalamic submedius neurons to lumbar vertebra thrust. Experimental Brain Research. PMID 28687855 DOI: 10.1007/S00221-017-5013-5  0.344
2017 Little JW. Modeling human lumbar spinal osteoarthritis and low back pain through preclinical studies The Faseb Journal. 31. DOI: 10.1096/Fasebj.31.1_Supplement.245.2  0.54
2017 Richey M, Reed N, Reed W, Little J. (180) The maintenance of NGF-induced persistent low back muscle pain is associated with lumbar spinal cord astrocytic hyperactivation The Journal of Pain. 18: S21. DOI: 10.1016/J.Jpain.2017.02.087  0.485
2017 Reed N, Richey M, Reed W, Little J. (179) Lumbar spinal cord microglial hyperactivation occurs during the development of persistent low back muscle pain The Journal of Pain. 18: S21. DOI: 10.1016/J.Jpain.2017.02.086  0.486
2015 Ford A, Castonguay A, Cottet M, Little JW, Chen Z, Symons-Liguori AM, Doyle T, Egan TM, Vanderah TW, De Konnick Y, Tosh DK, Jacobson KA, Salvemini D. Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6057-67. PMID 25878279 DOI: 10.1523/Jneurosci.4495-14.2015  0.661
2015 Little JW, Ford A, Symons-Liguori AM, Chen Z, Janes K, Doyle T, Xie J, Luongo L, Tosh DK, Maione S, Bannister K, Dickenson AH, Vanderah TW, Porreca F, Jacobson KA, et al. Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states. Brain : a Journal of Neurology. 138: 28-35. PMID 25414036 DOI: 10.1093/Brain/Awu330  0.768
2015 Janes K, Wahlman C, Little JW, Doyle T, Tosh DK, Jacobson KA, Salvemini D. Spinal neuroimmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy. Brain, Behavior, and Immunity. 44: 91-9. PMID 25220279 DOI: 10.1016/J.Bbi.2014.08.010  0.748
2015 Little J, Janes K, Chen Z, Wahlman C, Tosh D, Jacobson K, Salvemini D. (326) Supraspinal adenosine A3 receptor (A3AR) activation reverses chemotherapy-induced neuropathic pain through an IL-10 dependent mechanism The Journal of Pain. 16: S57. DOI: 10.1016/J.Jpain.2015.01.244  0.739
2014 Janes K, Little JW, Li C, Bryant L, Chen C, Chen Z, Kamocki K, Doyle T, Snider A, Esposito E, Cuzzocrea S, Bieberich E, Obeid L, Petrache I, Nicol G, et al. The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. The Journal of Biological Chemistry. 289: 21082-97. PMID 24876379 DOI: 10.1074/Jbc.M114.569574  0.767
2014 Little J, Chen Z, Ford A, Janes K, Doyle T, Tosh D, Jacobson K, Salvemini D. (297) Central adenosine A3 receptor (A3AR) activation reverses neuropathic pain The Journal of Pain. 15: S50. DOI: 10.1016/J.Jpain.2014.01.207  0.727
2013 Little JW, Cuzzocrea S, Bryant L, Esposito E, Doyle T, Rausaria S, Neumann WL, Salvemini D. Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance. Pain. 154: 978-86. PMID 23590939 DOI: 10.1016/J.Pain.2013.02.018  0.659
2012 Little JW, Chen Z, Doyle T, Porreca F, Ghaffari M, Bryant L, Neumann WL, Salvemini D. Supraspinal peroxynitrite modulates pain signaling by suppressing the endogenous opioid pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10797-808. PMID 22875915 DOI: 10.1523/Jneurosci.6345-11.2012  0.666
2012 Little JW, Doyle T, Salvemini D. Reactive nitroxidative species and nociceptive processing: determining the roles for nitric oxide, superoxide, and peroxynitrite in pain. Amino Acids. 42: 75-94. PMID 20552384 DOI: 10.1007/S00726-010-0633-0  0.686
2011 Salvemini D, Little JW, Doyle T, Neumann WL. Roles of reactive oxygen and nitrogen species in pain. Free Radical Biology & Medicine. 51: 951-66. PMID 21277369 DOI: 10.1016/J.Freeradbiomed.2011.01.026  0.655
2011 Little J, Chen Z, Doyle T, Porreca F, Salvemini D. Supraspinal descending facilitation of central sensitization depends on peroxynitrite regulation of opioid signaling The Journal of Pain. 12: P36. DOI: 10.1016/J.Jpain.2011.02.145  0.528
2009 Doyle T, Bryant L, Batinic-Haberle I, Little J, Cuzzocrea S, Masini E, Spasojevic I, Salvemini D. Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance Neuroscience. 164: 702-710. PMID 19607887 DOI: 10.1016/J.Neuroscience.2009.07.019  0.625
2005 Foley JL, Little JW, Starr FL, Frantz C, Vaezy S. Ultrasound-guided HIFU neurolysis of peripheral nerves to treat Spasticity and Pain Aip Conference Proceedings. 754: 30-32. DOI: 10.1063/1.1901592  0.334
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