Seth Grant - Publications

Wellcome Trust Sanger Institute, England, United Kingdom 
Molecular Neuroscience

177 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Sorokina O, Mclean C, Croning MDR, Heil KF, Wysocka E, He X, Sterratt D, Grant SGN, Simpson TI, Armstrong JD. Author Correction: A unified resource and configurable model of the synapse proteome and its role in disease. Scientific Reports. 11: 16240. PMID 34349214 DOI: 10.1038/s41598-021-95608-0  1
2021 Ramos-Vicente D, Grant SG, Bayés À. Metazoan Evolution and Diversity of Glutamate Receptors and Their Auxiliary Subunits. Neuropharmacology. 108640. PMID 34116111 DOI: 10.1016/j.neuropharm.2021.108640  1
2021 Sorokina O, Mclean C, Croning MDR, Heil KF, Wysocka E, He X, Sterratt D, Grant SGN, Simpson TI, Armstrong JD. A unified resource and configurable model of the synapse proteome and its role in disease. Scientific Reports. 11: 9967. PMID 33976238 DOI: 10.1038/s41598-021-88945-7  1
2020 Horner AE, Norris RH, McLaren-Jones R, Alexander L, Komiyama NH, Grant SGN, Nithianantharajah J, Kopanitsa MV. Learning and reaction times in mouse touchscreen tests are differentially impacted by mutations in genes encoding postsynaptic interacting proteins SYNGAP1, NLGN3, DLGAP1, DLGAP2 and SHANK2. Genes, Brain, and Behavior. e12723. PMID 33347690 DOI: 10.1111/gbb.12723  1
2020 Jamjoom AAB, Rhodes J, Andrews PJD, Grant SGN. The synapse in traumatic brain injury. Brain : a Journal of Neurology. PMID 33186462 DOI: 10.1093/brain/awaa321  0.01
2020 Grant SGN, Fransén E. The Synapse Diversity Dilemma: Molecular Heterogeneity Confounds Studies of Synapse Function. Frontiers in Synaptic Neuroscience. 12: 590403. PMID 33132891 DOI: 10.3389/fnsyn.2020.590403  1
2020 Santuy A, Tomás-Roca L, Rodríguez JR, González-Soriano J, Zhu F, Qiu Z, Grant SGN, DeFelipe J, Merchan-Perez A. Estimation of the number of synapses in the hippocampus and brain-wide by volume electron microscopy and genetic labeling. Scientific Reports. 10: 14014. PMID 32814795 DOI: 10.1038/s41598-020-70859-5  1
2020 Cizeron M, Qiu Z, Koniaris B, Gokhale R, Komiyama NH, Fransén E, Grant SGN. A brain-wide atlas of synapses across the mouse lifespan. Science (New York, N.Y.). PMID 32527927 DOI: 10.1126/Science.Aba3163  1
2020 Curran OE, Qiu Z, Smith C, Grant SGN. A single-synapse resolution survey of PSD95-positive synapses in twenty human brain regions. The European Journal of Neuroscience. PMID 32492218 DOI: 10.1111/Ejn.14846  1
2020 Broadhead MJ, Bonthron C, Arcinas L, Bez S, Zhu F, Goff F, Nylk J, Dholakia K, Gunn-Moore F, Grant SGN, Miles GB. Nanostructural Diversity of Synapses in the Mammalian Spinal Cord. Scientific Reports. 10: 8189. PMID 32424125 DOI: 10.1038/S41598-020-64874-9  1
2019 Zhu F, Collins MO, Harmse J, Choudhary JS, Grant SGN, Komiyama NH. Cell-type specific visualization and biochemical isolation of endogenous synaptic proteins in mice. The European Journal of Neuroscience. PMID 31621109 DOI: 10.1111/Ejn.14597  1
2019 Del Arroyo AG, Hadjihambi A, Sanchez J, Turovsky E, Kasymov V, Cain D, Nightingale TD, Lambden S, Grant SGN, Gourine AV, Ackland GL. NMDA receptor modulation of glutamate release in activated neutrophils. Ebiomedicine. PMID 31401196 DOI: 10.1016/J.Ebiom.2019.08.004  0.01
2019 Grant SGN. Synapse diversity and synaptome architecture in human genetic disorders. Human Molecular Genetics. PMID 31348488 DOI: 10.1093/hmg/ddz178  0.01
2019 Nakajima R, Takao K, Hattori S, Shoji H, Komiyama NH, Grant SGN, Miyakawa T. Comprehensive behavioral analysis of heterozygous Syngap1 knockout mice. Neuropsychopharmacology Reports. PMID 31323176 DOI: 10.1002/npr2.12073  1
2019 Kashiwagi Y, Higashi T, Obashi K, Sato Y, Komiyama NH, Grant SGN, Okabe S. Computational geometry analysis of dendritic spines by structured illumination microscopy. Nature Communications. 10: 1285. PMID 30894537 DOI: 10.1038/S41467-019-09337-0  1
2019 Grant SGN. The Synaptomic Theory of Behavior and Brain Disease. Cold Spring Harbor Symposia On Quantitative Biology. PMID 30886054 DOI: 10.1101/sqb.2018.83.037887  0.01
2019 Bach A, Clausen BH, Kristensen LK, Andersen MG, Ellman DG, Hansen PBL, Hasseldam H, Heitz M, Özcelik D, Tuck EJ, Kopanitsa MV, Grant SGN, Lykke-Hartmann K, Johansen FF, Lambertsen KL, et al. Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor. Neuropharmacology. PMID 30836092 DOI: 10.1016/j.neuropharm.2019.02.035  1
2018 Grant SGN. Synapse molecular complexity and the plasticity behaviour problem. Brain and Neuroscience Advances. 2: 2398212818810685. PMID 32166154 DOI: 10.1177/2398212818810685  0.01
2018 McKay S, Ryan TJ, McQueen J, Indersmitten T, Marwick KFM, Hasel P, Kopanitsa MV, Baxter PS, Martel MA, Kind PC, Wyllie DJA, O'Dell TJ, Grant SGN, Hardingham GE, Komiyama NH. The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences. Cell Reports. 25: 841-851.e4. PMID 30355491 DOI: 10.1016/J.Celrep.2018.09.089  1
2018 Delgado JY, Fink AE, Grant SGN, O'Dell TJ, Opazo P. Rapid homeostatic downregulation of LTP by extrasynaptic GluN2B receptors. Journal of Neurophysiology. PMID 30110236 DOI: 10.1152/Jn.00421.2018  1
2018 Masch JM, Steffens H, Fischer J, Engelhardt J, Hubrich J, Keller-Findeisen J, D'Este E, Urban NT, Grant SGN, Sahl SJ, Kamin D, Hell SW. Robust nanoscopy of a synaptic protein in living mice by organic-fluorophore labeling. Proceedings of the National Academy of Sciences of the United States of America. PMID 30082388 DOI: 10.1073/Pnas.1807104115  0.01
2018 Zhu F, Cizeron M, Qiu Z, Benavides-Piccione R, Kopanitsa MV, Skene NG, Koniaris B, DeFelipe J, Fransén E, Komiyama NH, Grant SGN. Architecture of the Mouse Brain Synaptome. Neuron. PMID 30078578 DOI: 10.1016/J.Neuron.2018.07.007  1
2018 Roy M, Sorokina O, McLean C, Tapia-González S, DeFelipe J, Armstrong JD, Grant SGN. Regional Diversity in the Postsynaptic Proteome of the Mouse Brain. Proteomes. 6. PMID 30071621 DOI: 10.3390/proteomes6030031  1
2018 Kopanitsa MV, Gou G, Afinowi NO, Bayés À, Grant SGN, Komiyama NH. Chronic treatment with a MEK inhibitor reverses enhanced excitatory field potentials in Syngap1 mice. Pharmacological Reports : Pr. 70: 777-783. PMID 29940508 DOI: 10.1016/J.Pharep.2018.02.021  1
2018 Wegner W, Mott AC, Grant SGN, Steffens H, Willig KI. In vivo STED microscopy visualizes PSD95 sub-structures and morphological changes over several hours in the mouse visual cortex. Scientific Reports. 8: 219. PMID 29317733 DOI: 10.1038/s41598-017-18640-z  0.01
2017 Horner AE, McLaughlin CL, Afinowi NO, Bussey TJ, Saksida LM, Komiyama NH, Grant SGN, Kopanitsa MV. Enhanced cognition and dysregulated hippocampal synaptic physiology in mice with a heterozygous deletion of PSD-95. The European Journal of Neuroscience. PMID 29237242 DOI: 10.1111/Ejn.13792  1
2017 Roy M, Sorokina O, Skene N, Simonnet C, Mazzo F, Zwart R, Sher E, Smith C, Armstrong JD, Grant SGN. Proteomic analysis of postsynaptic proteins in regions of the human neocortex. Nature Neuroscience. PMID 29203896 DOI: 10.1038/S41593-017-0025-9  1
2017 Fernández E, Collins MO, Frank RAW, Zhu F, Kopanitsa MV, Nithianantharajah J, Lemprière SA, Fricker D, Elsegood KA, McLaughlin CL, Croning MDR, Mclean C, Armstrong JD, Hill WD, Deary IJ, ... ... Grant SGN, et al. Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence. Cell Reports. 21: 679-691. PMID 29045836 DOI: 10.1016/J.Celrep.2017.09.045  1
2017 Skene NG, Roy M, Grant SG. A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia. Elife. 6. PMID 28893375 DOI: 10.7554/Elife.17915  1
2017 McQueen J, Ryan TJ, McKay S, Marwick KF, Baxter PE, Carpanini SM, Wishart TM, Gillingwater TH, Manson JC, Wyllie DJ, Grant SG, McColl B, Komiyama N, Hardingham GE. Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of DAPK1. Elife. 6. PMID 28731405 DOI: 10.7554/Elife.17161  1
2017 Frank RA, Grant SG. Supramolecular organization of NMDA receptors and the postsynaptic density. Current Opinion in Neurobiology. 45: 139-147. PMID 28577431 DOI: 10.1016/j.conb.2017.05.019  0.01
2017 Frank RAW, Zhu F, Komiyama NH, Grant SGN. Hierarchical organisation and genetically separable subfamilies of PSD95 postsynaptic supercomplexes. Journal of Neurochemistry. PMID 28452394 DOI: 10.1111/Jnc.14056  1
2017 Bayés À, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG. Evolution of complexity in the zebrafish synapse proteome. Nature Communications. 8: 14613. PMID 28252024 DOI: 10.1038/Ncomms14613  1
2017 Shukla A, Beroun A, Panopoulou M, Neumann PA, Grant SG, Olive MF, Dong Y, Schlüter OM. Calcium-permeable AMPA receptors and silent synapses in cocaine-conditioned place preference. The Embo Journal. PMID 28077487 DOI: 10.15252/Embj.201695465  0.04
2017 Benevento M, Oomen CA, Horner AE, Amiri H, Jacobs T, Pauwels C, Frega M, Kleefstra T, Kopanitsa MV, Grant SG, Bussey TJ, Saksida LM, Van der Zee CE, van Bokhoven H, Glennon JC, et al. Haploinsufficiency of EHMT1 improves pattern separation and increases hippocampal cell proliferation. Scientific Reports. 7: 40284. PMID 28071689 DOI: 10.1038/Srep40284  1
2016 van de Lagemaat LN, Stanford LE, Pettit C, Strathdee DJ, Strathdee KE, Elsegood KA, Fricker DG, Croning MD, Komiyama NH, Grant SG. Standardised experiments in mutant mice reveal behavioural similarity on 129S5 and C57BL/6J backgrounds. Genes, Brain, and Behavior. PMID 27886459 DOI: 10.1111/Gbb.12364  1
2016 Crocker-Buque A, Currie SP, Luz LL, Grant SG, Duffy KR, Kind PC, Daw MI. Altered Thalamocortical Development in the SAP102 Knockout Model of Intellectual Disability. Human Molecular Genetics. PMID 27466188 DOI: 10.1093/Hmg/Ddw244  1
2016 Frank RA, Komiyama NH, Ryan TJ, Zhu F, O'Dell TJ, Grant SG. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nature Communications. 7: 11264. PMID 27117477 DOI: 10.1038/Ncomms11264  1
2016 Broadhead MJ, Horrocks MH, Zhu F, Muresan L, Benavides-Piccione R, DeFelipe J, Fricker D, Kopanitsa MV, Duncan RR, Klenerman D, Komiyama NH, Lee SF, Grant SG. PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits. Scientific Reports. 6: 24626. PMID 27109929 DOI: 10.1038/Srep24626  1
2016 Skene NG, Grant SG. Identification of Vulnerable Cell Types in Major Brain Disorders Using Single Cell Transcriptomes and Expression Weighted Cell Type Enrichment. Frontiers in Neuroscience. 10: 16. PMID 26858593 DOI: 10.3389/Fnins.2016.00016  1
2016 Grant SG. The molecular evolution of the vertebrate behavioural repertoire. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 371. PMID 26598730 DOI: 10.1098/rstb.2015.0051  1
2015 Barnes SA, Wijetunge LS, Jackson AD, Katsanevaki D, Osterweil EK, Komiyama NH, Grant SG, Bear MF, Nägerl UV, Kind PC, Wyllie DJ. Convergence of Hippocampal Pathophysiology in Syngap+/- and Fmr1-/y Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15073-81. PMID 26558778 DOI: 10.1523/Jneurosci.1087-15.2015  1
2015 Nithianantharajah J, McKechanie AG, Stewart TJ, Johnstone M, Blackwood DH, St Clair D, Grant SG, Bussey TJ, Saksida LM. Bridging the translational divide: identical cognitive touchscreen testing in mice and humans carrying mutations in a disease-relevant homologous gene. Scientific Reports. 5: 14613. PMID 26423861 DOI: 10.1038/Srep14613  1
2015 Grant SG, Bagni C, O'Dell TJ. Synaptopathy - From Biology to Therapy. Neuropharmacology. PMID 26292261 DOI: 10.1016/J.Neuropharm.2015.08.022  1
2015 Charlesworth P, Morton A, Eglen SJ, Komiyama NH, Grant SG. Canalization of genetic and pharmacological perturbations in developing primary neuronal activity patterns. Neuropharmacology. PMID 26211975 DOI: 10.1016/J.Neuropharm.2015.07.027  1
2015 Farzana F, Zalm R, Chen N, Li KW, Grant SG, Smit AB, Toonen RF, Verhage M. Neurobeachin Regulates Glutamate- and GABA-Receptor Targeting to Synapses via Distinct Pathways. Molecular Neurobiology. PMID 25934101 DOI: 10.1007/S12035-015-9164-8  1
2015 Kiselycznyk C, Jury NJ, Halladay LR, Nakazawa K, Mishina M, Sprengel R, Grant SG, Svenningsson P, Holmes A. NMDA receptor subunits and associated signaling molecules mediating antidepressant-related effects of NMDA-GluN2B antagonism. Behavioural Brain Research. 287: 89-95. PMID 25800971 DOI: 10.1016/J.Bbr.2015.03.023  1
2015 Charlesworth P, Cotterill E, Morton A, Grant SG, Eglen SJ. Quantitative differences in developmental profiles of spontaneous activity in cortical and hippocampal cultures. Neural Development. 10: 1. PMID 25626996 DOI: 10.1186/S13064-014-0028-0  1
2015 Daut RA, Busch EF, Ihne J, Fisher D, Mishina M, Grant SG, Camp M, Holmes A. Tolerance to ethanol intoxication after chronic ethanol: role of GluN2A and PSD-95. Addiction Biology. 20: 259-62. PMID 24397780 DOI: 10.1111/Adb.12110  1
2015 Milner LC, Shirley RL, Kozell LB, Walter NA, Kruse LC, Komiyama NH, Grant SG, Buck KJ. Novel MPDZ/MUPP1 transgenic and knockdown models confirm Mpdz's role in ethanol withdrawal and support its role in voluntary ethanol consumption. Addiction Biology. 20: 143-7. PMID 24118405 DOI: 10.1111/Adb.12087  1
2014 Bayés À, Collins MO, Galtrey CM, Simonnet C, Roy M, Croning MD, Gou G, van de Lagemaat LN, Milward D, Whittle IR, Smith C, Choudhary JS, Grant SG. Human post-mortem synapse proteome integrity screening for proteomic studies of postsynaptic complexes. Molecular Brain. 7: 88. PMID 25429717 DOI: 10.1186/S13041-014-0088-4  1
2014 Gegg M, Böttcher A, Burtscher I, Hasenoeder S, Van Campenhout C, Aichler M, Walch A, Grant SG, Lickert H. Flattop regulates basal body docking and positioning in mono- and multiciliated cells. Elife. 3. PMID 25296022 DOI: 10.7554/eLife.03842  1
2014 Zhang J, Saur T, Duke AN, Grant SG, Platt DM, Rowlett JK, Isacson O, Yao WD. Motor impairments, striatal degeneration, and altered dopamine-glutamate interplay in mice lacking PSD-95. Journal of Neurogenetics. 28: 98-111. PMID 24702501 DOI: 10.3109/01677063.2014.892486  1
2014 Purcell SM, Moran JL, Fromer M, Ruderfer D, Solovieff N, Roussos P, O'Dushlaine C, Chambert K, Bergen SE, Kähler A, Duncan L, Stahl E, Genovese G, Fernández E, Collins MO, ... ... Grant SG, et al. A polygenic burden of rare disruptive mutations in schizophrenia. Nature. 506: 185-90. PMID 24463508 DOI: 10.1038/Nature12975  1
2014 Fromer M, Pocklington AJ, Kavanagh DH, Williams HJ, Dwyer S, Gormley P, Georgieva L, Rees E, Palta P, Ruderfer DM, Carrera N, Humphreys I, Johnson JS, Roussos P, Barker DD, ... ... Grant SG, et al. De novo mutations in schizophrenia implicate synaptic networks. Nature. 506: 179-84. PMID 24463507 DOI: 10.1038/Nature12929  1
2013 Axten JM, Romeril SP, Shu A, Ralph J, Medina JR, Feng Y, Li WH, Grant SW, Heerding DA, Minthorn E, Mencken T, Gaul N, Goetz A, Stanley T, Hassell AM, et al. Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development. Acs Medicinal Chemistry Letters. 4: 964-8. PMID 24900593 DOI: 10.1021/ml400228e  1
2013 Grant SG. SnapShot: Organizational principles of the postsynaptic proteome. Neuron. 80: 534.e1. PMID 24139049 DOI: 10.1016/j.neuron.2013.10.014  1
2013 De Rubeis S, Pasciuto E, Li KW, Fernández E, Di Marino D, Buzzi A, Ostroff LE, Klann E, Zwartkruis FJ, Komiyama NH, Grant SG, Poujol C, Choquet D, Achsel T, Posthuma D, et al. CYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formation. Neuron. 79: 1169-82. PMID 24050404 DOI: 10.1016/J.Neuron.2013.06.039  1
2013 Nithianantharajah J, Grant SG. Cognitive components in mice and humans: combining genetics and touchscreens for medical translation. Neurobiology of Learning and Memory. 105: 13-9. PMID 23796634 DOI: 10.1016/j.nlm.2013.06.006  1
2013 Nithianantharajah J, Komiyama NH, McKechanie A, Johnstone M, Blackwood DH, St Clair D, Emes RD, van de Lagemaat LN, Saksida LM, Bussey TJ, Grant SG. Synaptic scaffold evolution generated components of vertebrate cognitive complexity. Nature Neuroscience. 16: 16-24. PMID 23201973 DOI: 10.1038/Nn.3276  1
2013 Ryan TJ, Kopanitsa MV, Indersmitten T, Nithianantharajah J, Afinowi NO, Pettit C, Stanford LE, Sprengel R, Saksida LM, Bussey TJ, O'Dell TJ, Grant SG, Komiyama NH. Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior. Nature Neuroscience. 16: 25-32. PMID 23201971 DOI: 10.1038/Nn.3277  1
2013 von Eichborn J, Dunkel M, Gohlke BO, Preissner SC, Hoffmann MF, Bauer JM, Armstrong JD, Schaefer MH, Andrade-Navarro MA, Le Novere N, Croning MD, Grant SG, van Nierop P, Smit AB, Preissner R. SynSysNet: integration of experimental data on synaptic protein-protein interactions with drug-target relations. Nucleic Acids Research. 41: D834-40. PMID 23143269 DOI: 10.1093/nar/gks1040  1
2013 Debrouse L, Hurd B, Kiselycznyk C, Plitt A, Todaro A, Mishina M, Grant SG, Camp M, Gunduz-Cinar O, Holmes A. Probing the modulation of acute ethanol intoxication by pharmacological manipulation of the NMDAR glycine co-agonist site. Alcoholism, Clinical and Experimental Research. 37: 223-33. PMID 22934986 DOI: 10.1111/J.1530-0277.2012.01922.X  1
2012 Verma SK, Tian X, LaFrance LV, Duquenne C, Suarez DP, Newlander KA, Romeril SP, Burgess JL, Grant SW, Brackley JA, Graves AP, Scherzer DA, Shu A, Thompson C, Ott HM, et al. Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2. Acs Medicinal Chemistry Letters. 3: 1091-6. PMID 24900432 DOI: 10.1021/ml3003346  1
2012 Buck KJ, Milner LC, Denmark DL, Grant SG, Kozell LB. Discovering genes involved in alcohol dependence and other alcohol responses: role of animal models. Alcohol Research : Current Reviews. 34: 367-74. PMID 23134054  1
2012 Manakov SA, Morton A, Enright AJ, Grant SG. A Neuronal Transcriptome Response Involving Stress Pathways is Buffered by Neuronal microRNAs. Frontiers in Neuroscience. 6: 156. PMID 23115547 DOI: 10.3389/Fnins.2012.00156  1
2012 Bayés A, Collins MO, Croning MD, van de Lagemaat LN, Choudhary JS, Grant SG. Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins. Plos One. 7: e46683. PMID 23071613 DOI: 10.1371/journal.pone.0046683  1
2012 Coba MP, Komiyama NH, Nithianantharajah J, Kopanitsa MV, Indersmitten T, Skene NG, Tuck EJ, Fricker DG, Elsegood KA, Stanford LE, Afinowi NO, Saksida LM, Bussey TJ, O'Dell TJ, Grant SG. TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13987-99. PMID 23035106 DOI: 10.1523/Jneurosci.2433-12.2012  1
2012 Hawrylycz MJ, Lein ES, Guillozet-Bongaarts AL, Shen EH, Ng L, Miller JA, van de Lagemaat LN, Smith KA, Ebbert A, Riley ZL, Abajian C, Beckmann CF, Bernard A, Bertagnolli D, Boe AF, ... ... Grant SG, et al. An anatomically comprehensive atlas of the adult human brain transcriptome. Nature. 489: 391-9. PMID 22996553 DOI: 10.1038/Nature11405  1
2012 Axten JM, Medina JR, Feng Y, Shu A, Romeril SP, Grant SW, Li WH, Heerding DA, Minthorn E, Mencken T, Atkins C, Liu Q, Rabindran S, Kumar R, Hong X, et al. Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK). Journal of Medicinal Chemistry. 55: 7193-207. PMID 22827572 DOI: 10.1021/jm300713s  1
2012 Emes RD, Grant SG. Evolution of synapse complexity and diversity. Annual Review of Neuroscience. 35: 111-31. PMID 22715880 DOI: 10.1146/Annurev-Neuro-062111-150433  1
2012 McMahon AC, Barnett MW, O'Leary TS, Stoney PN, Collins MO, Papadia S, Choudhary JS, Komiyama NH, Grant SG, Hardingham GE, Wyllie DJ, Kind PC. SynGAP isoforms exert opposing effects on synaptic strength. Nature Communications. 3: 900. PMID 22692543 DOI: 10.1038/Ncomms1900  1
2012 Axten JM, Medina JR, Blackledge CW, Duquenne C, Grant SW, Bobko MA, Peng T, Miller WH, Pinckney T, Gallagher TF, Kulkarni S, Lewandowski T, Van Aller GS, Zonis R, Ward P, et al. Acylprolinamides: a new class of peptide deformylase inhibitors with in vivo antibacterial activity. Bioorganic & Medicinal Chemistry Letters. 22: 4028-32. PMID 22579486 DOI: 10.1016/j.bmcl.2012.04.086  1
2012 Martel MA, Ryan TJ, Bell KF, Fowler JH, McMahon A, Al-Mubarak B, Komiyama NH, Horsburgh K, Kind PC, Grant SG, Wyllie DJ, Hardingham GE. The subtype of GluN2 C-terminal domain determines the response to excitotoxic insults. Neuron. 74: 543-56. PMID 22578505 DOI: 10.1016/J.Neuron.2012.03.021  1
2012 Grant SG. Synaptopathies: diseases of the synaptome. Current Opinion in Neurobiology. 22: 522-9. PMID 22409856 DOI: 10.1016/j.conb.2012.02.002  1
2011 Van Campenhout CA, Eitelhuber A, Gloeckner CJ, Giallonardo P, Gegg M, Oller H, Grant SG, Krappmann D, Ueffing M, Lickert H. Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases. Developmental Cell. 21: 479-91. PMID 21920314 DOI: 10.1016/j.devcel.2011.08.003  1
2011 Frank RA, McRae AF, Pocklington AJ, van de Lagemaat LN, Navarro P, Croning MD, Komiyama NH, Bradley SJ, Challiss RA, Armstrong JD, Finn RD, Malloy MP, MacLean AW, Harris SE, Starr JM, ... ... Grant SG, et al. Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder. Plos One. 6: e19011. PMID 21559497 DOI: 10.1371/journal.pone.0019011  1
2011 Emes RD, Grant SG. The human postsynaptic density shares conserved elements with proteomes of unicellular eukaryotes and prokaryotes. Frontiers in Neuroscience. 5: 44. PMID 21503141 DOI: 10.3389/Fnins.2011.00044  1
2011 MacLaren EJ, Charlesworth P, Coba MP, Grant SG. Knockdown of mental disorder susceptibility genes disrupts neuronal network physiology in vitro. Molecular and Cellular Neurosciences. 47: 93-9. PMID 21440632 DOI: 10.1016/J.Mcn.2010.12.014  1
2011 Medina JR, Becker CJ, Blackledge CW, Duquenne C, Feng Y, Grant SW, Heerding D, Li WH, Miller WH, Romeril SP, Scherzer D, Shu A, Bobko MA, Chadderton AR, Dumble M, et al. Structure-based design of potent and selective 3-phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Journal of Medicinal Chemistry. 54: 1871-95. PMID 21341675 DOI: 10.1021/jm101527u  1
2011 Camp MC, Feyder M, Ihne J, Palachick B, Hurd B, Karlsson RM, Noronha B, Chen YC, Coba MP, Grant SG, Holmes A. A novel role for PSD-95 in mediating ethanol intoxication, drinking and place preference. Addiction Biology. 16: 428-39. PMID 21309945 DOI: 10.1111/J.1369-1600.2010.00282.X  1
2011 Moody TD, Watabe AM, Indersmitten T, Komiyama NH, Grant SG, O'Dell TJ. Beta-adrenergic receptor activation rescues theta frequency stimulation-induced LTP deficits in mice expressing C-terminally truncated NMDA receptor GluN2A subunits. Learning & Memory (Cold Spring Harbor, N.Y.). 18: 118-27. PMID 21257779 DOI: 10.1101/Lm.2045311  1
2011 Bayés A, van de Lagemaat LN, Collins MO, Croning MD, Whittle IR, Choudhary JS, Grant SG. Characterization of the proteome, diseases and evolution of the human postsynaptic density. Nature Neuroscience. 14: 19-21. PMID 21170055 DOI: 10.1038/nn.2719  1
2010 Feyder M, Karlsson RM, Mathur P, Lyman M, Bock R, Momenan R, Munasinghe J, Scattoni ML, Ihne J, Camp M, Graybeal C, Strathdee D, Begg A, Alvarez VA, Kirsch P, ... ... Grant SG, et al. Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndrome. The American Journal of Psychiatry. 167: 1508-17. PMID 20952458 DOI: 10.1176/Appi.Ajp.2010.10040484  1
2010 Schapitz IU, Behrend B, Pechmann Y, Lappe-Siefke C, Kneussel SJ, Wallace KE, Stempel AV, Buck F, Grant SG, Schweizer M, Schmitz D, Schwarz JR, Holzbaur EL, Kneussel M. Neuroligin 1 is dynamically exchanged at postsynaptic sites. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 12733-44. PMID 20861378 DOI: 10.1523/Jneurosci.0896-10.2010  1
2010 van de Lagemaat LN, Grant SG. Genome variation and complexity in the autism spectrum. Neuron. 67: 8-10. PMID 20624587 DOI: 10.1016/j.neuron.2010.06.026  1
2010 Delint-Ramirez I, Fernández E, Bayés A, Kicsi E, Komiyama NH, Grant SG. In vivo composition of NMDA receptor signaling complexes differs between membrane subdomains and is modulated by PSD-95 and PSD-93. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8162-70. PMID 20554866 DOI: 10.1523/JNEUROSCI.1792-10.2010  1
2010 Arbuckle MI, Komiyama NH, Delaney A, Coba M, Garry EM, Rosie R, Allchorne AJ, Forsyth LH, Bence M, Carlisle HJ, O'Dell TJ, Mitchell R, Fleetwood-Walker SM, Grant SG. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment. Embo Reports. 11: 473-8. PMID 20467438 DOI: 10.1038/Embor.2010.63  1
2010 Grant SG. Targeted TAP tags, phosphoproteomes and the biology of thought. Expert Review of Proteomics. 7: 169-71. PMID 20377382 DOI: 10.1586/epr.09.109  1
2010 Medina JR, Grant SW, Axten JM, Miller WH, Donatelli CA, Hardwicke MA, Oleykowski CA, Liao Q, Plant R, Xiang H. Discovery of a new series of Aurora inhibitors through truncation of GSK1070916. Bioorganic & Medicinal Chemistry Letters. 20: 2552-5. PMID 20335034 DOI: 10.1016/j.bmcl.2010.02.091  1
2010 Tam GW, van de Lagemaat LN, Redon R, Strathdee KE, Croning MD, Malloy MP, Muir WJ, Pickard BS, Deary IJ, Blackwood DH, Carter NP, Grant SG. Confirmed rare copy number variants implicate novel genes in schizophrenia. Biochemical Society Transactions. 38: 445-51. PMID 20298200 DOI: 10.1042/BST0380445  1
2010 Croning MD, Fricker DG, Komiyama NH, Grant SG. Automated design of genomic Southern blot probes. Bmc Genomics. 11: 74. PMID 20113467 DOI: 10.1186/1471-2164-11-74  1
2010 Grant SG. Computing behaviour in complex synapses: Synapse proteome complexity and the evolution of behaviour and disease The Biochemist. 32: 6-9. DOI: 10.1042/bio03202006  0.01
2009 Tam GW, Redon R, Carter NP, Grant SG. The role of DNA copy number variation in schizophrenia. Biological Psychiatry. 66: 1005-12. PMID 19748074 DOI: 10.1016/j.biopsych.2009.07.027  1
2009 Ryan TJ, Grant SG. The origin and evolution of synapses. Nature Reviews. Neuroscience. 10: 701-12. PMID 19738623 DOI: 10.1038/Nrn2717  1
2009 Manakov SA, Grant SG, Enright AJ. Reciprocal regulation of microRNA and mRNA profiles in neuronal development and synapse formation. Bmc Genomics. 10: 419. PMID 19737397 DOI: 10.1186/1471-2164-10-419  1
2009 Bayés A, Grant SG. Neuroproteomics: understanding the molecular organization and complexity of the brain. Nature Reviews. Neuroscience. 10: 635-46. PMID 19693028 DOI: 10.1038/nrn2701  1
2009 Abbas AI, Yadav PN, Yao WD, Arbuckle MI, Grant SG, Caron MG, Roth BL. PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7124-36. PMID 19494135 DOI: 10.1523/Jneurosci.1090-09.2009  1
2009 Fernández E, Collins MO, Uren RT, Kopanitsa MV, Komiyama NH, Croning MD, Zografos L, Armstrong JD, Choudhary JS, Grant SG. Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins. Molecular Systems Biology. 5: 269. PMID 19455133 DOI: 10.1038/msb.2009.27  1
2009 Câmara J, Wang Z, Nunes-Fonseca C, Friedman HC, Grove M, Sherman DL, Komiyama NH, Grant SG, Brophy PJ, Peterson A, ffrench-Constant C. Integrin-mediated axoglial interactions initiate myelination in the central nervous system. The Journal of Cell Biology. 185: 699-712. PMID 19451276 DOI: 10.1083/jcb.200807010  1
2009 Coba MP, Pocklington AJ, Collins MO, Kopanitsa MV, Uren RT, Swamy S, Croning MD, Choudhary JS, Grant SG. Neurotransmitters drive combinatorial multistate postsynaptic density networks. Science Signaling. 2: ra19. PMID 19401593 DOI: 10.1126/Scisignal.2000102  1
2009 Zhang J, Xu TX, Hallett PJ, Watanabe M, Grant SG, Isacson O, Yao WD. PSD-95 uncouples dopamine-glutamate interaction in the D1/PSD-95/NMDA receptor complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2948-60. PMID 19261890 DOI: 10.1523/Jneurosci.4424-08.2009  1
2009 Croning MD, Marshall MC, McLaren P, Armstrong JD, Grant SG. G2Cdb: the Genes to Cognition database. Nucleic Acids Research. 37: D846-51. PMID 18984621 DOI: 10.1093/nar/gkn700  1
2008 Bender J, Benfey P, Bergmann D, Borevitz J, Coruzzi G, Dangl J, Dean C, Ecker J, Estelle M, Glazebrook J, Grant S, Guerinot ML, Gutierrez R, Long J, Nordborg M, et al. 2020 vision for biology: the role of plants in addressing grand challenges in biology. Molecular Plant. 1: 561-3. PMID 19825561 DOI: 10.1093/Mp/Ssn040  0.01
2008 Horresh I, Poliak S, Grant S, Bredt D, Rasband MN, Peles E. Multiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 14213-22. PMID 19109503 DOI: 10.1523/Jneurosci.3398-08.2008  1
2008 Carlisle HJ, Fink AE, Grant SG, O'Dell TJ. Opposing effects of PSD-93 and PSD-95 on long-term potentiation and spike timing-dependent plasticity. The Journal of Physiology. 586: 5885-900. PMID 18936077 DOI: 10.1113/Jphysiol.2008.163469  1
2008 Coba MP, Valor LM, Kopanitsa MV, Afinowi NO, Grant SG. Kinase networks integrate profiles of N-methyl-D-aspartate receptor-mediated gene expression in hippocampus. The Journal of Biological Chemistry. 283: 34101-7. PMID 18815127 DOI: 10.1074/Jbc.M804951200  1
2008 Emes RD, Pocklington AJ, Anderson CN, Bayes A, Collins MO, Vickers CA, Croning MD, Malik BR, Choudhary JS, Armstrong JD, Grant SG. Evolutionary expansion and anatomical specialization of synapse proteome complexity. Nature Neuroscience. 11: 799-806. PMID 18536710 DOI: 10.1038/Nn.2135  1
2008 Collins MO, Yu L, Campuzano I, Grant SG, Choudhary JS. Phosphoproteomic analysis of the mouse brain cytosol reveals a predominance of protein phosphorylation in regions of intrinsic sequence disorder. Molecular & Cellular Proteomics : McP. 7: 1331-48. PMID 18388127 DOI: 10.1074/mcp.M700564-MCP200  1
2008 Polgár E, Watanabe M, Hartmann B, Grant SG, Todd AJ. Expression of AMPA receptor subunits at synapses in laminae I-III of the rodent spinal dorsal horn. Molecular Pain. 4: 5. PMID 18215271 DOI: 10.1186/1744-8069-4-5  1
2008 Ryan TJ, Emes RD, Grant SG, Komiyama NH. Evolution of NMDA receptor cytoplasmic interaction domains: implications for organisation of synaptic signalling complexes. Bmc Neuroscience. 9: 6. PMID 18197970 DOI: 10.1186/1471-2202-9-6  1
2008 Park CS, Elgersma Y, Grant SG, Morrison JH. alpha-Isoform of calcium-calmodulin-dependent protein kinase II and postsynaptic density protein 95 differentially regulate synaptic expression of NR2A- and NR2B-containing N-methyl-d-aspartate receptors in hippocampus. Neuroscience. 151: 43-55. PMID 18082335 DOI: 10.1016/J.Neuroscience.2007.09.075  1
2008 Husi H, Grant SGN. Isolation of 2000-kDa complexes of N-methyl-d-aspartate receptor and postsynaptic density 95 from mouse brain Journal of Neurochemistry. 77: 281-291. DOI: 10.1046/j.1471-4159.2001.00248.x  0.01
2007 Valor LM, Grant SG. Clustered gene expression changes flank targeted gene loci in knockout mice. Plos One. 2: e1303. PMID 18074027 DOI: 10.1371/journal.pone.0001303  1
2007 Delgado JY, Coba M, Anderson CN, Thompson KR, Gray EE, Heusner CL, Martin KC, Grant SG, O'Dell TJ. NMDA receptor activation dephosphorylates AMPA receptor glutamate receptor 1 subunits at threonine 840. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13210-21. PMID 18045915 DOI: 10.1523/Jneurosci.3056-07.2007  1
2007 Collins MO, Grant SG. Supramolecular signalling complexes in the nervous system Sub-Cellular Biochemistry. 43: 185-207. PMID 17953395 DOI: 10.1007/978-1-4020-5943-8_9  1
2007 Grant SG. Toward a molecular catalogue of synapses. Brain Research Reviews. 55: 445-9. PMID 17572504 DOI: 10.1016/j.brainresrev.2007.05.003  1
2007 Zalfa F, Eleuteri B, Dickson KS, Mercaldo V, De Rubeis S, di Penta A, Tabolacci E, Chiurazzi P, Neri G, Grant SG, Bagni C. A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability. Nature Neuroscience. 10: 578-87. PMID 17417632 DOI: 10.1038/Nn1893  1
2007 Zhang J, Vinuela A, Neely MH, Hallett PJ, Grant SG, Miller GM, Isacson O, Caron MG, Yao WD. Inhibition of the dopamine D1 receptor signaling by PSD-95. The Journal of Biological Chemistry. 282: 15778-89. PMID 17369255 DOI: 10.1074/Jbc.M611485200  1
2007 Valor LM, Charlesworth P, Humphreys L, Anderson CN, Grant SG. Network activity-independent coordinated gene expression program for synapse assembly. Proceedings of the National Academy of Sciences of the United States of America. 104: 4658-63. PMID 17360580 DOI: 10.1073/pnas.0609071104  1
2007 Cuthbert PC, Stanford LE, Coba MP, Ainge JA, Fink AE, Opazo P, Delgado JY, Komiyama NH, O'Dell TJ, Grant SG. Synapse-associated protein 102/dlgh3 couples the NMDA receptor to specific plasticity pathways and learning strategies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2673-82. PMID 17344405 DOI: 10.1523/Jneurosci.4457-06.2007  1
2007 Grove M, Komiyama NH, Nave KA, Grant SG, Sherman DL, Brophy PJ. FAK is required for axonal sorting by Schwann cells. The Journal of Cell Biology. 176: 277-82. PMID 17242067 DOI: 10.1083/jcb.200609021  1
2007 Laumonnier F, Cuthbert PC, Grant SG. The role of neuronal complexes in human X-linked brain diseases. American Journal of Human Genetics. 80: 205-20. PMID 17236127 DOI: 10.1086/511441  1
2007 Valor LM, Grant SGN. Integrating synapse proteomics with transcriptional regulation Behavior Genetics. 37: 18-30. PMID 16977502 DOI: 10.1007/s10519-006-9114-3  1
2007 Komiyama NH, Grant SG. The Genes to Cognition programme Neuroscience Research. 58: S30. DOI: 10.1016/j.neures.2007.06.176  0.01
2006 Strathdee D, Ibbotson H, Grant SG. Expression of transgenes targeted to the Gt(ROSA)26Sor locus is orientation dependent. Plos One. 1: e4. PMID 17183668 DOI: 10.1371/journal.pone.0000004  1
2006 Plath N, Ohana O, Dammermann B, Errington ML, Schmitz D, Gross C, Mao X, Engelsberg A, Mahlke C, Welzl H, Kobalz U, Stawrakakis A, Fernandez E, Waltereit R, Bick-Sander A, ... ... Grant SG, et al. Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories. Neuron. 52: 437-44. PMID 17088210 DOI: 10.1016/J.Neuron.2006.08.024  1
2006 Elias GM, Funke L, Stein V, Grant SG, Bredt DS, Nicoll RA. Synapse-specific and developmentally regulated targeting of AMPA receptors by a family of MAGUK scaffolding proteins. Neuron. 52: 307-20. PMID 17046693 DOI: 10.1016/J.Neuron.2006.09.012  1
2006 Kopanitsa MV, Afinowi NO, Grant SG. Recording long-term potentiation of synaptic transmission by three-dimensional multi-electrode arrays. Bmc Neuroscience. 7: 61. PMID 16942609 DOI: 10.1186/1471-2202-7-61  1
2006 Armstrong JD, Pocklington AJ, Cumiskey MA, Grant SG. Reconstructing protein complexes: from proteomics to systems biology. Proteomics. 6: 4724-31. PMID 16892485 DOI: 10.1002/pmic.200500895  1
2006 Anderson CN, Grant SG. High throughput protein expression screening in the nervous system--needs and limitations. The Journal of Physiology. 575: 367-72. PMID 16793899 DOI: 10.1113/jphysiol.2006.113795  1
2006 Pocklington AJ, Armstrong JD, Grant SGN. Organization of brain complexity - Synapse proteome form and function Briefings in Functional Genomics and Proteomics. 5: 66-73. PMID 16769682 DOI: 10.1093/bfgp/ell013  1
2006 Pocklington AJ, Cumiskey M, Armstrong JD, Grant SG. The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour. Molecular Systems Biology. 2: 2006.0023. PMID 16738568 DOI: 10.1038/msb4100041  1
2006 Vickers CA, Stephens B, Bowen J, Arbuthnott GW, Grant SG, Ingham CA. Neurone specific regulation of dendritic spines in vivo by post synaptic density 95 protein (PSD-95). Brain Research. 1090: 89-98. PMID 16677619 DOI: 10.1016/j.brainres.2006.03.075  1
2006 Collins MO, Husi H, Yu L, Brandon JM, Anderson CN, Blackstock WP, Choudhary JS, Grant SG. Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome. Journal of Neurochemistry. 97: 16-23. PMID 16635246 DOI: 10.1111/j.1471-4159.2005.03507.x  1
2006 Grant SW, Zhu K, Zhang Y, Castle SL. Stereoselective cascade reactions that incorporate a 7-exo acyl radical cyclization. Organic Letters. 8: 1867-70. PMID 16623571 DOI: 10.1021/Ol0604264  1
2006 Barnett MW, Watson RF, Vitalis T, Porter K, Komiyama NH, Stoney PN, Gillingwater TH, Grant SG, Kind PC. Synaptic Ras GTPase activating protein regulates pattern formation in the trigeminal system of mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1355-65. PMID 16452659 DOI: 10.1523/Jneurosci.3164-05.2006  1
2006 Grant SGN. Michael Rutter: Genes and behavior: nature-nurture interplay explained Genes, Brain and Behavior. 5: 303-303. DOI: 10.1111/J.1601-183X.2006.00219.X  0.01
2006 Elias G, Funke L, Stein V, Grant S, Bredt D, Nicoll R. [ST8]: PSD‐MAGUK‐specific developmetal regulation of AMPA receptor synaptic expression International Journal of Developmental Neuroscience. 24: 493-493. DOI: 10.1016/J.Ijdevneu.2006.09.058  0.01
2005 Grant SGN, Malinow R, Rumpel S, Zador A, Ledoux J. AMPA receptor trafficking and GluR1 [2] (multiple letters) Science. 310: 234-235. PMID 16224003 DOI: 10.1126/science.310.5746.234  1
2005 Toresson H, Grant SG. Dynamic distribution of endoplasmic reticulum in hippocampal neuron dendritic spines. The European Journal of Neuroscience. 22: 1793-8. PMID 16197520 DOI: 10.1111/j.1460-9568.2005.04342.x  1
2005 Grant SG, Marshall MC, Page KL, Cumiskey MA, Armstrong JD. Synapse proteomics of multiprotein complexes: en route from genes to nervous system diseases. Human Molecular Genetics. 14: R225-34. PMID 16150739 DOI: 10.1093/hmg/ddi330  1
2005 Collins MO, Yu L, Husi H, Blackstock WP, Choudhary JS, Grant SG. Robust enrichment of phosphorylated species in complex mixtures by sequential protein and peptide metal-affinity chromatography and analysis by tandem mass spectrometry. Science's Stke : Signal Transduction Knowledge Environment. 2005: pl6. PMID 16118397 DOI: 10.1126/stke.2982005pl6  1
2005 Porter K, Komiyama NH, Vitalis T, Kind PC, Grant SG. Differential expression of two NMDA receptor interacting proteins, PSD-95 and SynGAP during mouse development. The European Journal of Neuroscience. 21: 351-62. PMID 15673435 DOI: 10.1111/J.1460-9568.2005.03874.X  1
2005 Bence M, Arbuckle MI, Dickson KS, Grant SG. Analyses of murine postsynaptic density-95 identify novel isoforms and potential translational control elements. Brain Research. Molecular Brain Research. 133: 143-52. PMID 15661374 DOI: 10.1016/J.Molbrainres.2004.09.024  1
2005 Collins MO, Yu L, Coba MP, Husi H, Campuzano I, Blackstock WP, Choudhary JS, Grant SG. Proteomic analysis of in vivo phosphorylated synaptic proteins. The Journal of Biological Chemistry. 280: 5972-82. PMID 15572359 DOI: 10.1074/Jbc.M411220200  1
2004 McLean GW, Komiyama NH, Serrels B, Asano H, Reynolds L, Conti F, Hodivala-Dilke K, Metzger D, Chambon P, Grant SG, Frame MC. Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression. Genes & Development. 18: 2998-3003. PMID 15601818 DOI: 10.1101/Gad.316304  1
2004 Choudhary J, Grant SG. Proteomics in postgenomic neuroscience: the end of the beginning. Nature Neuroscience. 7: 440-5. PMID 15114355 DOI: 10.1038/nn1240  0.01
2004 Yao WD, Gainetdinov RR, Arbuckle MI, Sotnikova TD, Cyr M, Beaulieu JM, Torres GE, Grant SG, Caron MG. Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Neuron. 41: 625-38. PMID 14980210 DOI: 10.1016/S0896-6273(04)00048-0  1
2004 Hermjakob H, Montecchi-Palazzi L, Bader G, Wojcik J, Salwinski L, Ceol A, Moore S, Orchard S, Sarkans U, von Mering C, Roechert B, Poux S, Jung E, Mersch H, Kersey P, ... ... Grant SG, et al. The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data. Nature Biotechnology. 22: 177-83. PMID 14755292 DOI: 10.1038/Nbt926  1
2003 Grant SG. Synapse signalling complexes and networks: machines underlying cognition. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 25: 1229-35. PMID 14635258 DOI: 10.1002/bies.10381  0.01
2003 Grant SG. Systems biology in neuroscience: bridging genes to cognition. Current Opinion in Neurobiology. 13: 577-82. PMID 14630221 DOI: 10.1016/j.conb.2003.09.016  0.01
2003 Nada S, Shima T, Yanai H, Husi H, Grant SG, Okada M, Akiyama T. Identification of PSD-93 as a substrate for the Src family tyrosine kinase Fyn. The Journal of Biological Chemistry. 278: 47610-21. PMID 13129934 DOI: 10.1074/jbc.M303873200  1
2003 Opazo P, Watabe AM, Grant SG, O'Dell TJ. Phosphatidylinositol 3-kinase regulates the induction of long-term potentiation through extracellular signal-related kinase-independent mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3679-88. PMID 12736339 DOI: 10.1523/Jneurosci.23-09-03679.2003  1
2003 Nourry C, Grant SG, Borg JP. PDZ domain proteins: plug and play! Science's Stke : Signal Transduction Knowledge Environment. 2003: RE7. PMID 12709532 DOI: 10.1126/Stke.2003.179.Re7  1
2003 Garry EM, Moss A, Delaney A, O'Neill F, Blakemore J, Bowen J, Husi H, Mitchell R, Grant SG, Fleetwood-Walker SM. Neuropathic sensitization of behavioral reflexes and spinal NMDA receptor/CaM kinase II interactions are disrupted in PSD-95 mutant mice. Current Biology : Cb. 13: 321-8. PMID 12593798 DOI: 10.1016/S0960-9822(03)00084-8  1
2003 Fagiolini M, Katagiri H, Miyamoto H, Mori H, Grant SG, Mishina M, Hensch TK. Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling. Proceedings of the National Academy of Sciences of the United States of America. 100: 2854-9. PMID 12591944 DOI: 10.1073/Pnas.0536089100  1
2002 Rasband MN, Park EW, Zhen D, Arbuckle MI, Poliak S, Peles E, Grant SG, Trimmer JS. Clustering of neuronal potassium channels is independent of their interaction with PSD-95. The Journal of Cell Biology. 159: 663-72. PMID 12438413 DOI: 10.1083/Jcb.200206024  1
2002 Komiyama NH, Watabe AM, Carlisle HJ, Porter K, Charlesworth P, Monti J, Strathdee DJ, O'Carroll CM, Martin SJ, Morris RG, O'Dell TJ, Grant SG. SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9721-32. PMID 12427827 DOI: 10.1523/Jneurosci.22-22-09721.2002  1
2002 Grant SG. Putting tubby on the MAP. Nature Genetics. 30: 347-8. PMID 11925554 DOI: 10.1038/ng0402-347  0.01
2001 Grant SG, O'Dell TJ. Multiprotein complex signaling and the plasticity problem. Current Opinion in Neurobiology. 11: 363-8. PMID 11399436 DOI: 10.1016/S0959-4388(00)00220-8  1
2001 Husi H, Grant SG. Proteomics of the nervous system. Trends in Neurosciences. 24: 259-66. PMID 11311377 DOI: 10.1016/S0166-2236(00)01792-6  0.01
2000 Husi H, Ward MA, Choudhary JS, Blackstock WP, Grant SG. Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. Nature Neuroscience. 3: 661-9. PMID 10862698 DOI: 10.1038/76615  0.04
1998 Migaud M, Charlesworth P, Dempster M, Webster LC, Watabe AM, Makhinson M, He Y, Ramsay MF, Morris RG, Morrison JH, O'Dell TJ, Grant SG. Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein. Nature. 396: 433-9. PMID 9853749 DOI: 10.1038/24790  1
1997 Brambilla R, Gnesutta N, Minichiello L, White G, Roylance AJ, Herron CE, Ramsey M, Wolfer DP, Cestari V, Rossi-Arnaud C, Grant SG, Chapman PF, Lipp HP, Sturani E, Klein R. A role for the Ras signalling pathway in synaptic transmission and long-term memory. Nature. 390: 281-6. PMID 9384379 DOI: 10.1038/36849  1
1997 Silva AJ, Simpson EM, Takahashi JS, Lipp HP, Nakanishi S, Wehner JM, Giese KP, Tully T, Abel T, Chapman PF, Fox K, Grant S, Itohara S, Lathe R, Mayford M, et al. Mutant mice and neuroscience: Recommendations concerning genetic background Neuron. 19: 755-759. PMID 9354323 DOI: 10.1016/S0896-6273(00)80958-7  1
1995 Grant SG. Gene targeting and synaptic plasticity. Current Opinion in Neurobiology. 4: 687-92. PMID 7849524 DOI: 10.1016/0959-4388(94)90010-8  0.01
1994 Grant SGN, Silva AJ. Targeting learning Trends in Neurosciences. 17: 71-75. PMID 7512771 DOI: 10.1016/0166-2236(94)90077-9  1
1994 Grant SGN, O'Dell TJ. Targeting tyrosine kinase genes and long-term potentiation Seminars in the Neurosciences. 6: 45-52. DOI: 10.1006/smns.1994.1006  1
1993 Sudol M, Grant SG, Maisonpierre PC. Proto-oncogenes and signaling processes in neural tissues. Neurochemistry International. 22: 369-84. PMID 8457773 DOI: 10.1016/0197-0186(93)90019-2  1
1991 Hicks BA, Stein R, Efrat S, Grant S, Hanahan D, Demetriou AA. Transplantation of beta cells from transgenic mice into nude athymic diabetic rats restores glucose regulation. Diabetes Research and Clinical Practice. 14: 157-64. PMID 1778108 DOI: 10.1016/0168-8227(91)90016-7  1
1991 O'Dell TJ, Kandel ER, Grant SG. Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors. Nature. 353: 558-60. PMID 1656271 DOI: 10.1038/353558a0  1
1988 Dycaico MJ, Grant SG, Felts K, Nichols WS, Geller SA, Hager JH, Pollard AJ, Kohler SW, Short HP, Jirik FR. Neonatal hepatitis induced by alpha 1-antitrypsin: a transgenic mouse model. Science (New York, N.Y.). 242: 1409-12. PMID 3264419 DOI: 10.1126/Science.3264419  1
1988 Efrat S, Linde S, Kofod H, Spector D, Delannoy M, Grant S, Hanahan D, Baekkeskov S. Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene. Proceedings of the National Academy of Sciences of the United States of America. 85: 9037-41. PMID 2848253 DOI: 10.1073/Pnas.85.23.9037  1
1987 Chamberlain JS, Grant SG, Reeves AA, Mullins LJ, Stephenson DA, Hoffman EP, Monaco AP, Kunkel LM, Caskey CT, Chapman VM. Regional localization of the murine Duchenne muscular dystrophy gene on the mouse X chromosome. Somatic Cell and Molecular Genetics. 13: 671-8. PMID 2890215 DOI: 10.1007/Bf01534487  1
1970 Grant S, Croning M, Armstrong J. G2Cdb: a database of the synapse. Frontiers in Neuroinformatics. DOI: 10.3389/Conf.Neuro.11.2009.08.039  0.01
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