Francisco Bezanilla - Related publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Structure-Function in Voltage Dependent Ionic Channels and Transport proteins
Website:
http://nerve.bsd.uchicago.edu/FB/index.html
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Garza-López E, Aldana A, Darszon A, Nishigaki T, López-González I. Ca3.1 channel pore pseudo-symmetry revealed by selectivity filter mutations in its domains I/II. Cell Calcium. 89: 102214. PMID 32428730 DOI: 10.1016/j.ceca.2020.102214   
2020 Clark MD, Contreras GF, Shen R, Perozo E. Electromechanical coupling in the hyperpolarization-activated K channel KAT1. Nature. PMID 32461693 DOI: 10.1038/s41586-020-2335-4   
2020 Fletcher-Taylor S, Thapa P, Sepela RJ, Kaakati R, Yarov-Yarovoy V, Sack JT, Cohen BE. Distinguishing Potassium Channel Resting State Conformations in Live Cells with Environment-Sensitive Fluorescence. Acs Chemical Neuroscience. PMID 32579336 DOI: 10.1021/acschemneuro.0c00276   
2020 Chen X, Bründl M, Friesacher T, Stary-Weinzinger A. Computational Insights Into Voltage Dependence of Polyamine Block in a Strong Inwardly Rectifying K Channel. Frontiers in Pharmacology. 11: 721. PMID 32499707 DOI: 10.3389/fphar.2020.00721   
2020 Fahanik-Babaei J, Rezaee B, Nazari M, Torabi N, Saghiri R, Sauve R, Eliassi A. A new brain mitochondrial sodium-sensitive potassium channel: effect of sodium ions on respiratory chain activity. Journal of Cell Science. PMID 32327555 DOI: 10.1242/jcs.242446   
2020 Hasan S, Megaro A, Cenciarini M, Coretti L, Botti FM, Imbrici P, Steinbusch HWM, Hunter T, Hunter G, Pessia M, D'Adamo MC. Electromechanical coupling of the Kv1.1 voltage-gated K channel is fine-tuned by the simplest amino acid residue in the S4-S5 linker. Pflugers Archiv : European Journal of Physiology. PMID 32577860 DOI: 10.1007/s00424-020-02414-0   
2020 Jackson WF. Ion channels and the regulation of myogenic tone in peripheral arterioles. Current Topics in Membranes. 85: 19-58. PMID 32402640 DOI: 10.1016/bs.ctm.2020.01.002   
2020 Mudumbi KC, Czapiewski R, Ruba A, Junod SL, Li Y, Luo W, Ngo C, Ospina V, Schirmer EC, Yang W. Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores. Nature Communications. 11: 2184. PMID 32366843 DOI: 10.1038/s41467-020-16033-x   
2020 Hernandez A, Hernández-Centeno R, Espino-Saldaña ÁE, Martínez-Torres A. HCN2 activation modulation: An electrophysiological and molecular study of the well-preserved LCI sequence in the pore channel. Archives of Biochemistry and Biophysics. 108436. PMID 32492375 DOI: 10.1016/j.abb.2020.108436   
2020 Szanto TG, Zakany F, Papp F, Varga Z, Deutsch CJ, Panyi G. The activation gate controls steady-state inactivation and recovery from inactivation in Shaker. The Journal of General Physiology. 152. PMID 32442242 DOI: 10.1085/jgp.202012591   
2020 Gao J, Wei H, Cano A, Kurgan L. PSIONplus Server for Accurate Multi-Label Prediction of Ion Channels and Their Types. Biomolecules. 10. PMID 32517331 DOI: 10.3390/biom10060876   
2020 Zhu W, Li T, Silva JR, Chen J. Conservation and divergence in NaChBac and Na1.7 pharmacology reveals novel drug interaction mechanisms. Scientific Reports. 10: 10730. PMID 32612253 DOI: 10.1038/s41598-020-67761-5   
2020 Yang W, Wang Y, Guo J, He L, Zhou Y, Zheng H, Liu Z, Zhu P, Zhang XC. Cryo-EM structure of CLHM1 ion channel from Caenorhabditis elegans. Protein Science : a Publication of the Protein Society. PMID 32557855 DOI: 10.1002/pro.3904   
2020 Hou Y, Wang F, Chen Z, Shi V. Coordination of a Dual-Channel Pharmaceutical Supply Chain Based on the Susceptible-Infected-Susceptible Epidemic Model. International Journal of Environmental Research and Public Health. 17. PMID 32397305 DOI: 10.3390/ijerph17093292   
2020 Van Theemsche KM, Van de Sande DV, Snyders DJ, Labro AJ. Hydrophobic Drug/Toxin Binding Sites in Voltage-Dependent K and Na Channels. Frontiers in Pharmacology. 11: 735. PMID 32499709 DOI: 10.3389/fphar.2020.00735   
2020 Rödström KEJ, Kiper AK, Zhang W, Rinné S, Pike ACW, Goldstein M, Conrad LJ, Delbeck M, Hahn MG, Meier H, Platzk M, Quigley A, Speedman D, Shrestha L, Mukhopadhyay SMM, et al. A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature. PMID 32499642 DOI: 10.1038/s41586-020-2250-8   
2020 Fagnen C, Bannwarth L, Oubella I, Forest E, De Zorzi R, de Araujo A, Mhoumadi Y, Bendahhou S, Perahia D, Vénien-Bryan C. New Structural insights into Kir channel gating from molecular simulations, HDX-MS and functional studies. Scientific Reports. 10: 8392. PMID 32439887 DOI: 10.1038/s41598-020-65246-z   
2020 Guet-McCreight A, Skinner FK. Computationally going where experiments cannot: a dynamical assessment of dendritic ion channel currents during -like states. F1000research. 9: 180. PMID 32595950 DOI: 10.12688/f1000research.22584.2   
2020 Zheng X, Fu Z, Su D, Zhang Y, Li M, Pan Y, Li H, Li S, Grassucci RA, Ren Z, Hu Z, Li X, Zhou M, Li G, Frank J, et al. Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel. Nature Structural & Molecular Biology. PMID 32483338 DOI: 10.1038/s41594-020-0433-5   
2020 Geragotelis AD, Wood ML, Göddeke H, Hong L, Webster PD, Wong EK, Freites JA, Tombola F, Tobias DJ. Voltage-dependent structural models of the human Hv1 proton channel from long-timescale molecular dynamics simulations. Proceedings of the National Academy of Sciences of the United States of America. PMID 32461356 DOI: 10.1073/pnas.1920943117   
2020 Brewer KR, Kuenze G, Vanoye CG, George AL, Meiler J, Sanders CR. Structures Illuminate Cardiac Ion Channel Functions in Health and in Long QT Syndrome. Frontiers in Pharmacology. 11: 550. PMID 32431610 DOI: 10.3389/fphar.2020.00550   
2020 Black KA, He S, Jin R, Miller DM, Bolla JR, Clarke OB, Johnson P, Windley M, Burns CJ, Hill AP, Laver D, Robinson CV, Smith BJ, Gulbis JM. A constricted opening in Kir channels does not impede potassium conduction. Nature Communications. 11: 3024. PMID 32541684 DOI: 10.1038/s41467-020-16842-0   
2020 Scarnati MS, Clarke SG, Pang ZP, Paradiso KG. Presynaptic Calcium Channel Open Probability and Changes in Calcium Influx Throughout the Action Potential Determined Using AP-Waveforms. Frontiers in Synaptic Neuroscience. 12: 17. PMID 32425764 DOI: 10.3389/fnsyn.2020.00017   
2020 Sancho M, Welsh DG. K channels in the microvasculature: Regulatory properties and the lipid-hemodynamic environment. Current Topics in Membranes. 85: 227-259. PMID 32402641 DOI: 10.1016/bs.ctm.2020.01.006   
2020 Chambers L, Dorrance AM. Regulation of ion channels in the microcirculation by mineralocorticoid receptor activation. Current Topics in Membranes. 85: 151-185. PMID 32402638 DOI: 10.1016/bs.ctm.2020.02.001   
2020 Peters CH, Watkins AR, Poirier OL, Ruben PC. E1784K, the most common Brugada syndrome and long-QT syndrome type 3 mutant, disrupts sodium channel inactivation through two separate mechanisms. The Journal of General Physiology. 152. PMID 32569350 DOI: 10.1085/jgp.202012595   
2020 Nowak MB, Greer-Short A, Wan X, Wu X, Deschênes I, Weinberg SH, Poelzing S. Intercellular Sodium Regulates Repolarization in Cardiac Tissue with Sodium Channel Gain of Function. Biophysical Journal. PMID 32402243 DOI: 10.1016/j.bpj.2020.04.014   
2020 Hou J, Daniels PN, Burke MD. Small Molecule Channels Harness Membrane Potential to Concentrate Potassium in trk1Δtrk2Δ Yeast. Acs Chemical Biology. PMID 32427463 DOI: 10.1021/acschembio.0c00180   
2020 Hanemaaijer NAK, Popovic MA, Wilders X, Grasman S, Pavón Arocas O, Kole MHP. Ca entry through Na channels generates submillisecond axonal Ca signaling. Elife. 9. PMID 32553116 DOI: 10.7554/eLife.54566   
2020 Li C, Chen H, Chen Q, Shi H, Yang X, Wang K, Liu J. Lipophilic G-quadruplex Isomers as Biomimetic Ion Channels for Conformation- dependent Selective Transmembrane Transport. Analytical Chemistry. PMID 32564593 DOI: 10.1021/acs.analchem.0c02222   
2020 Tiwari SK, Bhat S, Mahato KK. Design and Fabrication of Low-cost Microfluidic Channel for Biomedical Application. Scientific Reports. 10: 9215. PMID 32514070 DOI: 10.1038/s41598-020-65995-x   
2020 Cheung TP, Choe JY, Richmond JE, Kim H. BK channel density is regulated by endoplasmic reticulum associated degradation and influenced by the SKN-1A/NRF1 transcription factor. Plos Genetics. 16: e1008829. PMID 32502151 DOI: 10.1371/journal.pgen.1008829   
2020 Yuen Chow C, Absalom N, Biggs K, King GF, Ma L. Venom-derived modulators of epilepsy-related ion channels. Biochemical Pharmacology. 114043. PMID 32445870 DOI: 10.1016/j.bcp.2020.114043   
2020 Neumaier F, Alpdogan S, Hescheler J, Schneider T. Zn2+-induced changes in Cav2.3 channel function: An electrophysiological and modeling study. The Journal of General Physiology. 152. PMID 32559275 DOI: 10.1085/jgp.202012585   
2020 Loh KWZ, Liang MC, Soong TW, Hu Z. Regulation of cardiovascular calcium channel activity by post-translational modifications or interacting proteins. Pflugers Archiv : European Journal of Physiology. PMID 32435990 DOI: 10.1007/s00424-020-02398-x   
2020 Zhang DM, Lin YF. Functional Modulation of Sarcolemmal K Channels by Atrial Natriuretic Peptide-Elicited Intracellular Signaling in Adult Rabbit Ventricular Cardiomyocytes. American Journal of Physiology. Cell Physiology. PMID 32432931 DOI: 10.1152/ajpcell.00409.2019   
2020 Deng Z, Maksaev G, Rau M, Xie Z, Hu H, Fitzpatrick JAJ, Yuan P. Gating of human TRPV3 in a lipid bilayer. Nature Structural & Molecular Biology. PMID 32572252 DOI: 10.1038/s41594-020-0428-2   
2020 Cai S, Tuohy P, Ma C, Kitamura N, Gomez K, Zhou Y, Ran D, Bellampalli SS, Yu J, Luo S, Dorame A, Ngan Pham NY, Molnar G, Streicher JM, Patek M, et al. A modulator of the low-voltage activated T-type calcium channel that reverses HIV glycoprotein 120-, paclitaxel-, and spinal nerve ligation-induced peripheral neuropathies. Pain. PMID 32541387 DOI: 10.1097/j.pain.0000000000001955   
2020 Méndez-Reséndiz KA, Enciso-Pablo Ó, González-Ramírez R, Juárez-Contreras R, Rosenbaum T, Morales-Lázaro SL. Steroids and TRP Channels: A Close Relationship. International Journal of Molecular Sciences. 21. PMID 32471309 DOI: 10.3390/ijms21113819   
2020 Ruan Z, Orozco IJ, Du J, Lü W. Structures of human pannexin 1 reveal ion pathways and mechanism of gating. Nature. PMID 32494015 DOI: 10.1038/s41586-020-2357-y   
2020 Al-Sabi A, Daly D, Rooney M, Hughes C, Kinsella GK, Kaza SK, Nolan K, Oliver Dolly J. Development of a selective inhibitor for Kv1.1 channels prevalent in demyelinated nerves. Bioorganic Chemistry. 100: 103918. PMID 32428746 DOI: 10.1016/j.bioorg.2020.103918   
2020 Zou X, Liu L, Xu J, Wang H, Tang WM. Few-Layered MoS2 Field-Effect Transistors with a Vertical Channel of Sub-10 nm. Acs Applied Materials & Interfaces. PMID 32610894 DOI: 10.1021/acsami.0c09060   
2020 Rohaim A, Gong L, Li J, Rui H, Blachowicz L, Roux B. Open and closed structures of a barium-blocked potassium channel. Journal of Molecular Biology. PMID 32615129 DOI: 10.1016/j.jmb.2020.06.012   
2020 Lewis A, McCrossan ZA, Manville RW, Popa MO, Cuello LG, Goldstein SAN. TOK channels use the two gates in classical K channels to achieve outward rectification. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32519783 DOI: 10.1096/fj.202000545R   
2020 Thapak P, Vaidya B, Joshi HC, Singh JN, Sharma SS. Therapeutic Potential of Pharmacological Agents Targeting TRP Channels in CNS Disorders. Pharmacological Research. 105026. PMID 32562815 DOI: 10.1016/j.phrs.2020.105026   
2020 Cardoso FC. Multi-targeting sodium and calcium channels using venom peptides for the treatment of complex ion channels-related diseases. Biochemical Pharmacology. 114107. PMID 32579958 DOI: 10.1016/j.bcp.2020.114107   
2020 Salvage SC, Huang CL, Jackson AP. Cell-Adhesion Properties of β-Subunits in the Regulation of Cardiomyocyte Sodium Channels. Biomolecules. 10. PMID 32630316 DOI: 10.3390/biom10070989   
2020 Benítez-Angeles M, Morales-Lázaro SL, Juárez-González E, Rosenbaum T. TRPV1: Structure, Endogenous Agonists, and Mechanisms. International Journal of Molecular Sciences. 21. PMID 32408609 DOI: 10.3390/ijms21103421   
2020 Rehman SM, Narayanan K, Nickerson AJ, Coon SD, Hoque KM, Sandle GI, Rajendran VM. Parallel intermediate conductance K (IK) and Cl (CLC2) channel activity mediates electroneutral K exit across basolateral membranes in rat distal colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 32567323 DOI: 10.1152/ajpgi.00011.2020   
2020 Pai VP, Cervera J, Mafe S, Willocq V, Lederer EK, Levin M. HCN2 Channel-Induced Rescue of Brain Teratogenesis Local and Long-Range Bioelectric Repair. Frontiers in Cellular Neuroscience. 14: 136. PMID 32528251 DOI: 10.3389/fncel.2020.00136