| Year |
Citation |
Score |
| 2023 |
Liao EE, Yang M, Nathan Kochen N, Vunnam N, Braun AR, Ferguson DM, Sachs JN. Proteasomal Stimulation by MK886 and Its Derivatives Can Rescue Tau-Induced Neurite Pathology. Molecular Neurobiology. PMID 37428404 DOI: 10.1007/s12035-023-03417-5 |
0.701 |
|
| 2023 |
Braun AR, Kochen NN, Yuen SL, Liao EE, Cornea RL, Thomas DD, Sachs JN. Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein. Asn Neuro. 15: 17590914231184086. PMID 37428128 DOI: 10.1177/17590914231184086 |
0.539 |
|
| 2023 |
Vunnam N, Yang M, Lo CH, Paulson C, Fiers WD, Huber E, Been M, Ferguson DM, Sachs JN. Zafirlukast Is a Promising Scaffold for Selectively Inhibiting TNFR1 Signaling. Acs Bio & Med Chem Au. 3: 270-282. PMID 37363080 DOI: 10.1021/acsbiomedchemau.2c00048 |
0.659 |
|
| 2023 |
Pandey AK, Buchholz CR, Nathan Kochen N, Pomerantz WCK, Braun AR, Sachs JN. pH Effects Can Dominate Chemical Shift Perturbations in H,N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions. Acs Chemical Neuroscience. PMID 36749138 DOI: 10.1021/acschemneuro.2c00782 |
0.54 |
|
| 2022 |
Ratnapriya S, Braun AR, Cervera Benet H, Carlson D, Ding S, Paulson CN, Mishra N, Sachs JN, Aldrich CC, Finzi A, Herschhorn A. Broad Tricyclic Ring Inhibitors Block SARS-CoV-2 Spike Function Required for Viral Entry. Acs Infectious Diseases. PMID 36153947 DOI: 10.1021/acsinfecdis.1c00658 |
0.561 |
|
| 2022 |
Nathan Kochen N, Vasandani V, Seaney D, Pandey AK, Walters MA, Braun AR, Sachs JN. Threonine Cavities Are Targetable Motifs That Control Alpha-Synuclein Fibril Growth. Acs Chemical Neuroscience. PMID 36001084 DOI: 10.1021/acschemneuro.2c00327 |
0.563 |
|
| 2021 |
Braun AR, Liao EE, Horvath M, Kalra P, Acosta K, Young MC, Kochen NN, Lo CH, Brown R, Evans MD, Pomerantz WCK, Rhoades E, Luk K, Cornea RL, Thomas DD, ... Sachs JN, et al. Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors. Npj Parkinson's Disease. 7: 52. PMID 34183676 DOI: 10.1038/s41531-021-00195-6 |
0.541 |
|
| 2021 |
Braun AR, Liao EE, Horvath M, Kalra P, Acosta K, Young MC, Kochen NN, Lo CH, Brown R, Evans MD, Pomerantz WCK, Rhoades E, Luk K, Cornea RL, Thomas DD, ... Sachs JN, et al. Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors. Npj Parkinson's Disease. 7: 52. PMID 34183676 DOI: 10.1038/s41531-021-00195-6 |
0.541 |
|
| 2020 |
Vunnam N, Szymonski S, Hirsova P, Gores G, Sachs JN, Hackel BJ. Noncompetitive allosteric antagonism of death receptor 5 by a synthetic affibody ligand. Biochemistry. PMID 32941010 DOI: 10.1021/Acs.Biochem.0C00529 |
0.675 |
|
| 2020 |
Lo CH, Huber EC, Sachs JN. Conformational states of TNFR1 as a molecular switch for receptor function. Protein Science : a Publication of the Protein Society. PMID 31960514 DOI: 10.1002/Pro.3829 |
0.395 |
|
| 2020 |
West A, Zoni V, Teague WE, Leonard AN, Vanni S, Gawrisch K, Tristram-Nagle S, Sachs JN, Klauda JB. How Do Ethanolamine Plasmalogens Contribute to Order and Structure of Neurological Membranes? The Journal of Physical Chemistry. B. PMID 31916765 DOI: 10.1021/Acs.Jpcb.9B08850 |
0.42 |
|
| 2020 |
Vunnam N, Szymonski S, Petra H, Gores GJ, Hackel B, Sachs J. Noncompetitive allosteric antagonism of death receptor 5 by an affibody discovered via yeast display The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05692 |
0.645 |
|
| 2019 |
Lo CH, Lim CK, Ding Z, Wickramasinghe SP, Braun AR, Ashe KH, Rhoades E, Thomas DD, Sachs JN. Targeting the ensemble of heterogeneous tau oligomers in cells: A novel small molecule screening platform for tauopathies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31653529 DOI: 10.1016/J.Jalz.2019.06.4954 |
0.569 |
|
| 2019 |
Hemmat M, Castle BT, Sachs JN, Odde DJ. Multiscale Computational Modeling of Tubulin-Tubulin Lateral Interaction. Biophysical Journal. PMID 31493861 DOI: 10.1016/J.Bpj.2019.08.011 |
0.335 |
|
| 2019 |
Lo CH, Schaaf TM, Grant BD, Lim CK, Bawaskar P, Aldrich CC, Thomas DD, Sachs JN. Noncompetitive inhibitors of TNFR1 probe conformational activation states. Science Signaling. 12. PMID 31363069 DOI: 10.1126/Scisignal.Aav5637 |
0.424 |
|
| 2018 |
Braun AR, Lacy MM, Ducas VC, Chen Z, Baumgart T, Rhoades E, Sachs JN. Correction to: α-Synuclein's Uniquely Long Amphipathic Helix Enhances its Membrane Binding and Remodeling Capacity. The Journal of Membrane Biology. PMID 30054671 DOI: 10.1007/S00232-018-0042-Y |
0.587 |
|
| 2018 |
Young M, Braun AR, Sachs JN, Hung Lo C. Developing Novel FRET Based Biosensors that Monitor α-Synuclein Assembly for Use in High Throughput Screening Biophysical Journal. 114: 77a. DOI: 10.1016/J.Bpj.2017.11.465 |
0.552 |
|
| 2018 |
Beaven AH, Romo TD, Lewis AK, Braun AR, Grossfield A, Sachs JN. Computational Studies of Alpha-Synuclein Fibril Formation and Stability Biophysical Journal. 114: 230a. DOI: 10.1016/J.Bpj.2017.11.1278 |
0.693 |
|
| 2017 |
Vunnam N, Lo CH, Grant BD, Thomas DD, Sachs JN. Soluble Extracellular Domain of Death Receptor 5 Inhibits TRAIL-induced Apoptosis by Disrupting Receptor-Receptor Interactions. Journal of Molecular Biology. PMID 28834692 DOI: 10.1016/J.Jmb.2017.08.009 |
0.401 |
|
| 2017 |
Vunnam N, Campbell-Bezat CK, Lewis AK, Sachs JN. Death Receptor 5 Activation Is Energetically Coupled to Opening of the Transmembrane Domain Dimer. Biophysical Journal. 113: 381-392. PMID 28746849 DOI: 10.1016/J.Bpj.2017.05.038 |
0.678 |
|
| 2017 |
Romo TD, Lewis AK, Braun AR, Grossfield A, Sachs JN. Minimal nucleation state of alpha-Synuclein is stabilized by dynamic threonine-water networks. Acs Chemical Neuroscience. PMID 28677385 DOI: 10.1021/Acschemneuro.7B00171 |
0.733 |
|
| 2017 |
Lo CH, Vunnam N, Lewis AK, Chiu TL, Brummel BE, Schaaf TM, Grant BD, Bawaskar P, Thomas DD, Sachs JN. An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors. Slas Discovery. 2472555217706478. PMID 28530838 DOI: 10.1177/2472555217706478 |
0.641 |
|
| 2017 |
Braun AR, Lacy MM, Ducas VC, Rhoades E, Sachs JN. α-Synuclein's Uniquely Long Amphipathic Helix Enhances its Membrane Binding and Remodeling Capacity. The Journal of Membrane Biology. PMID 28239748 DOI: 10.1007/S00232-017-9946-1 |
0.66 |
|
| 2017 |
Valley CC, Lewis AK, Sachs JN. Piecing it together: Unraveling the elusive structure-function relationship in single-pass membrane receptors. Biochimica Et Biophysica Acta. PMID 28089689 DOI: 10.1016/J.Bbamem.2017.01.016 |
0.808 |
|
| 2017 |
Senkow TL, Woldring DR, Kruziki M, Hackel BJ, Sachs JN. Evaluation of High Affinity Scaffolds from High-Throughput Discovery and Targeting DR5 and TNFR1 Biophysical Journal. 112: 530a. DOI: 10.1016/J.Bpj.2016.11.2865 |
0.598 |
|
| 2016 |
Hennig R, West A, Debus M, Saur M, Markl J, Sachs JN, Schneider D. The IM30/Vipp1 C-terminus associates with the lipid bilayer and modulates membrane fusion. Biochimica Et Biophysica Acta. PMID 27836697 DOI: 10.1016/J.Bbabio.2016.11.004 |
0.386 |
|
| 2016 |
Brummel BE, Braun AR, Sachs JN. Polyunsaturated chains in asymmetric lipids disorder raft mixtures and preferentially associate with α-Synuclein. Biochimica Et Biophysica Acta. PMID 27742354 DOI: 10.1016/J.Bbamem.2016.10.006 |
0.638 |
|
| 2016 |
Lewis AK, Valley CC, Peery SL, Brummel B, Braun AR, Karim C, Sachs JN. Death Receptor 5 Networks Require Membrane Cholesterol for Proper Structure and Function. Journal of Molecular Biology. PMID 27720987 DOI: 10.1016/J.Jmb.2016.10.001 |
0.815 |
|
| 2016 |
Lewis AK, Dunleavy KM, Senkow TL, Her C, Horn BT, Jersett MA, Mahling R, McCarthy MR, Perell GT, Valley CC, Karim CB, Gao J, Pomerantz WC, Thomas DD, Cembran A, ... ... Sachs JN, et al. Oxidation increases the strength of the methionine-aromatic interaction. Nature Chemical Biology. PMID 27547920 DOI: 10.1038/Nchembio.2159 |
0.788 |
|
| 2016 |
Romeo C, Weber MC, Zarei M, DeCicco D, Chand SN, Lobo AD, Winter JM, Sawicki JA, Sachs JN, Meisner-Kober N, Yeo CJ, Vadigepalli R, Tykocinski ML, Brody JR. HuR Contributes to TRAIL Resistance by Restricting Death Receptor 4 Expression in Pancreatic Cancer Cells. Molecular Cancer Research : McR. PMID 27053682 DOI: 10.1158/1541-7786.Mcr-15-0448 |
0.303 |
|
| 2016 |
West A, Brummel BE, Braun AR, Rhoades E, Sachs JN. Membrane remodeling and mechanics: Experiments and simulations of α-Synuclein. Biochimica Et Biophysica Acta. PMID 26972046 DOI: 10.1016/J.Bbamem.2016.03.012 |
0.654 |
|
| 2016 |
Hung Lo C, Lewis A, Schaaf T, Bawaskar P, Vunnam N, Peterson K, Thomas D, Sachs J. Manipulations of the TNF-Receptor Affinity and Oligomerization Characterized by Fluorescence Lifetime Measurements Biophysical Journal. 110: 490a. DOI: 10.1016/J.Bpj.2015.11.2618 |
0.672 |
|
| 2016 |
Brummel BE, Sachs J. Using Molecular Dynamics Simulations and Atomic Force Microscopy to Determine How α-Synuclein Affects Membrane Mechanics Biophysical Journal. 110: 243a. DOI: 10.1016/J.Bpj.2015.11.1339 |
0.408 |
|
| 2016 |
Senkow TL, Lewis AK, Sachs JN. Investigating the Role of Transmembrane Domain Cysteine Residues in the Organization of TNF Receptors Biophysical Journal. 110: 227a. DOI: 10.1016/J.Bpj.2015.11.1257 |
0.66 |
|
| 2016 |
West A, Brummel B, Sachs J. α-Synuclein Bound to Mitochondrial Membranes—Changes in Lipid Bilayer Structure and Mechanics Biophysical Journal. 110: 189a. DOI: 10.1016/J.Bpj.2015.11.1055 |
0.403 |
|
| 2015 |
Braun AR, Sachs JN. α-Synuclein Reduces Tension and Increases Undulations in Simulations of Small Unilamellar Vesicles. Biophysical Journal. 108: 1848-51. PMID 25902424 DOI: 10.1016/J.Bpj.2015.03.029 |
0.641 |
|
| 2015 |
Shi Z, Sachs JN, Rhoades E, Baumgart T. Biophysics of α-synuclein induced membrane remodelling. Physical Chemistry Chemical Physics : Pccp. 17: 15561-8. PMID 25665896 DOI: 10.1039/C4Cp05883F |
0.407 |
|
| 2015 |
Braun AR, Sachs JN. Alpha-Synuclein Stabilizes Small Unilamellar Vesicles by Reducing Both Membrane Surface Tension and Rigidity Biophysical Journal. 108: 547a. DOI: 10.1016/J.Bpj.2014.11.3001 |
0.643 |
|
| 2015 |
Senkow TL, Lewis AK, McCarthy MR, Her C, Thomas DD, Sachs JN. Methionine-Aromatic Interactions in Calmodulin: A Replica Exchange MD and EPR Spectroscopy Study Biophysical Journal. 108: 213a-214a. DOI: 10.1016/J.Bpj.2014.11.1180 |
0.634 |
|
| 2014 |
Braun AR, Sachs JN. Determining Structural and Mechanical Properties from Molecular Dynamics Simulations of Lipid Vesicles. Journal of Chemical Theory and Computation. 10: 4160-4168. PMID 25221448 DOI: 10.1021/Ct500460U |
0.646 |
|
| 2014 |
Tehei M, Perlmutter JD, Giusti F, Sachs JN, Zaccai G, Popot JL. Thermal fluctuations in amphipol A8-35 particles: a neutron scattering and molecular dynamics study. The Journal of Membrane Biology. 247: 897-908. PMID 25204390 DOI: 10.1007/S00232-014-9725-1 |
0.735 |
|
| 2014 |
Braun AR, Lacy MM, Ducas VC, Rhoades E, Sachs JN. α-Synuclein-induced membrane remodeling is driven by binding affinity, partition depth, and interleaflet order asymmetry. Journal of the American Chemical Society. 136: 9962-72. PMID 24960410 DOI: 10.1021/Ja5016958 |
0.671 |
|
| 2014 |
Perlmutter JD, Popot JL, Sachs JN. Molecular dynamics simulations of a membrane protein/amphipol complex. The Journal of Membrane Biology. 247: 883-95. PMID 24930025 DOI: 10.1007/S00232-014-9690-8 |
0.758 |
|
| 2014 |
Lewis AK, James ZM, McCaffrey JE, Braun AR, Karim CB, Thomas DD, Sachs JN. Open and closed conformations of the isolated transmembrane domain of death receptor 5 support a new model of activation. Biophysical Journal. 106: L21-4. PMID 24655519 DOI: 10.1016/J.Bpj.2014.01.044 |
0.758 |
|
| 2014 |
Lewis AK, Valley CC, Braun AR, Sachs JN. Quantitative Analysis of Ligand-Induced Supramolecular Clustering of Death Receptor 5 in Jurkat Cells Biophysical Journal. 106: 715a. DOI: 10.1016/J.Bpj.2013.11.3953 |
0.805 |
|
| 2014 |
Braun AR, Sachs JN. Extracting Structural and Mechanical Properties of Lipid Vesicles from Molecular Dynamics Simulations Biophysical Journal. 106: 710a. DOI: 10.1016/J.Bpj.2013.11.3915 |
0.658 |
|
| 2014 |
Lacy MM, Ducas VC, Braun AR, Sachs JN, Rhoades E. Assessing the Structural Dynamics and Membrane Interactions of the Disordered Protein Alpha-Synuclein Biophysical Journal. 106: 267a-268a. DOI: 10.1016/J.Bpj.2013.11.1568 |
0.664 |
|
| 2014 |
Lewis AK, Sachs JN. Oxidative Stress Modulates Bioactivity of Lymphotoxin, but not TNF, Through Site-Specific Oxidation of Methionine Residues Biophysical Journal. 106: 251a-252a. DOI: 10.1016/J.Bpj.2013.11.1481 |
0.656 |
|
| 2013 |
Braun AR, Sachs JN, Nagle JF. Comparing simulations of lipid bilayers to scattering data: the GROMOS 43A1-S3 force field. The Journal of Physical Chemistry. B. 117: 5065-72. PMID 23560979 DOI: 10.1021/Jp401718K |
0.594 |
|
| 2013 |
Braun AR, Sachs JN. α-Synuclein Induced Membrane Curvature: What is the Significance of Negative Gaussian Curvature Biophysical Journal. 104: 95a. DOI: 10.1016/J.Bpj.2012.11.564 |
0.664 |
|
| 2012 |
Valley CC, Cembran A, Perlmutter JD, Lewis AK, Labello NP, Gao J, Sachs JN. The methionine-aromatic motif plays a unique role in stabilizing protein structure. The Journal of Biological Chemistry. 287: 34979-91. PMID 22859300 DOI: 10.1074/Jbc.M112.374504 |
0.795 |
|
| 2012 |
Lewis AK, Valley CC, Sachs JN. TNFR1 signaling is associated with backbone conformational changes of receptor dimers consistent with overactivation in the R92Q TRAPS mutant. Biochemistry. 51: 6545-55. PMID 22799488 DOI: 10.1021/Bi3006626 |
0.808 |
|
| 2012 |
Pineda DM, Rittenhouse DW, Valley CC, Cozzitorto JA, Burkhart RA, Leiby B, Winter JM, Weber MC, Londin ER, Rigoutsos I, Yeo CJ, Gorospe M, Witkiewicz AK, Sachs JN, Brody JR. HuR's post-transcriptional regulation of Death Receptor 5 in pancreatic cancer cells. Cancer Biology & Therapy. 13: 946-55. PMID 22785201 DOI: 10.4161/Cbt.20952 |
0.749 |
|
| 2012 |
Valley CC, Lewis AK, Mudaliar DJ, Perlmutter JD, Braun AR, Karim CB, Thomas DD, Brody JR, Sachs JN. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor 5 networks that are highly organized. The Journal of Biological Chemistry. 287: 21265-78. PMID 22496450 DOI: 10.1074/Jbc.M111.306480 |
0.79 |
|
| 2012 |
Braun AR, Sevcsik E, Chin P, Rhoades E, Tristram-Nagle S, Sachs JN. α-Synuclein induces both positive mean curvature and negative Gaussian curvature in membranes. Journal of the American Chemical Society. 134: 2613-20. PMID 22211521 DOI: 10.1021/Ja208316H |
0.658 |
|
| 2012 |
Valley CC, Lewis AK, Mudaliar D, Sachs JN. Signaling in the Tumor Necrosis Factor Superfamily is Driven by Formation of Receptor Networks: Unraveling the Structural and Dynamic Paradigm Biophysical Journal. 102: 430a. DOI: 10.1016/J.Bpj.2011.11.2355 |
0.807 |
|
| 2012 |
Braun AR, Sevcsik E, Rhoades E, Tristram-Nagle S, Sachs JN. The Nature of Membrane Curvature-Induction by Amphipathic α-Helices Relies upon Protein Length: Simulations of α-Synuclein and H0 Biophysical Journal. 102: 237a. DOI: 10.1016/J.Bpj.2011.11.1301 |
0.658 |
|
| 2011 |
Valley CC, Perlmutter JD, Braun AR, Sachs JN. NaCl interactions with phosphatidylcholine bilayers do not alter membrane structure but induce long-range ordering of ions and water. The Journal of Membrane Biology. 244: 35-42. PMID 22015614 DOI: 10.1007/S00232-011-9395-1 |
0.797 |
|
| 2011 |
Perlmutter JD, Drasler WJ, Xie W, Gao J, Popot JL, Sachs JN. All-atom and coarse-grained molecular dynamics simulations of a membrane protein stabilizing polymer. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 10523-37. PMID 21806035 DOI: 10.1021/La202103V |
0.736 |
|
| 2011 |
Popot JL, Althoff T, Bagnard D, Banères JL, Bazzacco P, Billon-Denis E, Catoire LJ, Champeil P, Charvolin D, Cocco MJ, Crémel G, Dahmane T, de la Maza LM, Ebel C, Gabel F, ... ... Sachs JN, et al. Amphipols from A to Z. Annual Review of Biophysics. 40: 379-408. PMID 21545287 DOI: 10.1146/Annurev-Biophys-042910-155219 |
0.372 |
|
| 2011 |
Braun AR, Brandt EG, Edholm O, Nagle JF, Sachs JN. Determination of electron density profiles and area from simulations of undulating membranes. Biophysical Journal. 100: 2112-20. PMID 21539778 DOI: 10.1016/J.Bpj.2011.03.009 |
0.615 |
|
| 2011 |
Brandt EG, Braun AR, Sachs JN, Nagle JF, Edholm O. Interpretation of fluctuation spectra in lipid bilayer simulations. Biophysical Journal. 100: 2104-11. PMID 21539777 DOI: 10.1016/J.Bpj.2011.03.010 |
0.594 |
|
| 2011 |
Perlmutter JD, Sachs JN. Interleaflet interaction and asymmetry in phase separated lipid bilayers: molecular dynamics simulations. Journal of the American Chemical Society. 133: 6563-77. PMID 21473645 DOI: 10.1021/Ja106626R |
0.741 |
|
| 2011 |
Rittenhouse DW, Valley C, Cozzitorto JA, Richards NG, Talbott VA, Yeo CJ, Sachs JN, Witkiewicz AK, Brody JR. Abstract 4100: HuR regulates death receptor-5 (DR5, TRAIL-R2)-targeted treatment of pancreatic cancer cells Cancer Research. 71: 4100-4100. DOI: 10.1158/1538-7445.Am2011-4100 |
0.737 |
|
| 2011 |
Perlmutter JD, Sachs JN. Multi-Scale Molecular Dynamics Simulations of a Membrane Protein Stabilizing Polymer Biophysical Journal. 100: 640a. DOI: 10.1016/J.Bpj.2010.12.3678 |
0.752 |
|
| 2011 |
Brandt EG, Braun AR, Sachs JN, Nagle JF, Edholm O. Direct Fourier Analysis of Lipid Bilayer Fluctuations in Particle-Based Simulations Biophysical Journal. 100: 491a. DOI: 10.1016/J.Bpj.2010.12.2881 |
0.59 |
|
| 2011 |
Braun AR, Tristram-Nagle S, Sachs JN. Structure and Bending Rigidity of SOPC, SOPC-Cholesterol, and SOPC-LWYIK Bilayers: A Comparison of Molecular Dynamics and X-Ray Scattering Results Biophysical Journal. 100: 490a. DOI: 10.1016/J.Bpj.2010.12.2873 |
0.623 |
|
| 2011 |
Valley CC, Braun AR, Sachs JN. Pre-Ligand Assembly of TNF Receptors Through Covalent and Non-Covalent Interactions Biophysical Journal. 100: 419a-420a. DOI: 10.1016/J.Bpj.2010.12.2485 |
0.81 |
|
| 2011 |
Altun A, Bartlett RJ, Bergonzo C, Braun AR, Bylaska EJ, Daniel Crawford T, de Jong WA, Deumens E, Erik Nielsen J, Fortenberry RC, Govind N, Hayat S, Helms V, Jindal N, Johnston MA, ... ... Sachs JN, et al. Contributors Annual Reports in Computational Chemistry. 7: ix-xi. DOI: 10.1016/B978-0-444-53835-2.00017-1 |
0.453 |
|
| 2011 |
Braun AR, Sachs JN. Extracting Experimental Measurables from Molecular Dynamics Simulations of Membranes Annual Reports in Computational Chemistry. 7: 125-150. DOI: 10.1016/B978-0-444-53835-2.00006-7 |
0.635 |
|
| 2010 |
Braun AR, Frink LJ, Sachs JN. Probing the Molecular Structure of Polymer DNA Nanoparticles Via Fluids-DFT Biophysical Journal. 98: 658a. DOI: 10.1016/J.Bpj.2009.12.3608 |
0.553 |
|
| 2010 |
Braun AR, Edholm O, Brandt EG, Nagle JF, Sachs JN. Characterization of Electron Density Profiles and Area Per Lipid from MD Simulation of Large Undulating Bilayers Biophysical Journal. 98: 569a. DOI: 10.1016/J.Bpj.2009.12.3087 |
0.609 |
|
| 2010 |
Sachs JN, Perlmutter JD, Braun AR, Sevcsik E, Tristram-Nagle S, Rhoades E. Probing the Membrane Deformations Induced by Binding of Membrane Proteins: Alpha-Synuclein and CRAC Biophysical Journal. 98: 487a-488a. DOI: 10.1016/J.Bpj.2009.12.2655 |
0.809 |
|
| 2010 |
Perlmutter JD, Sachs JN. Simulations of Lipid Bilayer Domain Formation: Effects of Steroid Structure and Asymmetry Biophysical Journal. 98: 230a. DOI: 10.1016/J.Bpj.2009.12.1246 |
0.756 |
|
| 2009 |
Denning EJ, Crozier PS, Sachs JN, Woolf TB. From the gating charge response to pore domain movement: initial motions of Kv1.2 dynamics under physiological voltage changes. Molecular Membrane Biology. 26: 397-421. PMID 19883299 DOI: 10.3109/09687680903278539 |
0.582 |
|
| 2009 |
Perlmutter JD, Sachs JN. Inhibiting lateral domain formation in lipid bilayers: simulations of alternative steroid headgroup chemistries. Journal of the American Chemical Society. 131: 16362-3. PMID 19860442 DOI: 10.1021/Ja9079258 |
0.752 |
|
| 2009 |
Perlmutter JD, Sachs JN. Experimental verification of lipid bilayer structure through multi-scale modeling. Biochimica Et Biophysica Acta. 1788: 2284-90. PMID 19616507 DOI: 10.1016/J.Bbamem.2009.07.006 |
0.761 |
|
| 2009 |
Kucerka N, Nieh MP, Pencer J, Sachs JN, Katsaras J. What determines the thickness of a biological membrane. General Physiology and Biophysics. 28: 117-25. PMID 19592708 DOI: 10.4149/Gpb_2009_02_117 |
0.41 |
|
| 2009 |
Kajander T, Sachs JN, Goldman A, Regan L. Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering. The Journal of Biological Chemistry. 284: 25364-74. PMID 19586912 DOI: 10.1074/Jbc.M109.033894 |
0.341 |
|
| 2009 |
Perlmutter JD, Braun AR, Sachs JN. Curvature dynamics of alpha-synuclein familial Parkinson disease mutants: molecular simulations of the micelle- and bilayer-bound forms. The Journal of Biological Chemistry. 284: 7177-89. PMID 19126542 DOI: 10.1074/Jbc.M808895200 |
0.8 |
|
| 2009 |
Perlmutter JD, Braun AR, Sachs JN. Curvature Dynamics of α-Synuclein Familial Parkinson's Disease Mutants: Molecular Dynamics Simulations of the Micelle- and Membrane-Bound Forms Biophysical Journal. 96: 340a. DOI: 10.1016/J.Bpj.2008.12.3830 |
0.811 |
|
| 2009 |
Perlmutter JD, Sachs JN. Coarse-Grained Molecular Dynamics Simulations of an Inhomogeneous Ternary Lipid Bilayer Biophysical Journal. 96: 460a. DOI: 10.1016/J.Bpj.2008.12.2368 |
0.771 |
|
| 2009 |
Valley C, Sachs J. Stabilizing Interactions In TNF Ligand-receptor Binding Biophysical Journal. 96: 446a. DOI: 10.1016/J.Bpj.2008.12.2292 |
0.778 |
|
| 2009 |
Drasler WJ, Sachs JN. All-atom Molecular Dynamics Simulations of a Membrane Protein Stabilizing Polymer Biophysical Journal. 96: 41a. DOI: 10.1016/J.Bpj.2008.12.107 |
0.4 |
|
| 2008 |
Kucerka N, Perlmutter JD, Pan J, Tristram-Nagle S, Katsaras J, Sachs JN. The effect of cholesterol on short- and long-chain monounsaturated lipid bilayers as determined by molecular dynamics simulations and X-ray scattering. Biophysical Journal. 95: 2792-805. PMID 18515383 DOI: 10.1529/Biophysj.107.122465 |
0.756 |
|
| 2008 |
Kucerka N, Nagle JF, Sachs JN, Feller SE, Pencer J, Jackson A, Katsaras J. Lipid bilayer structure determined by the simultaneous analysis of neutron and X-ray scattering data. Biophysical Journal. 95: 2356-67. PMID 18502796 DOI: 10.1529/Biophysj.108.132662 |
0.335 |
|
| 2007 |
Kucerka N, Pencer J, Sachs JN, Nagle JF, Katsaras J. Curvature effect on the structure of phospholipid bilayers. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 1292-9. PMID 17241048 DOI: 10.1021/La062455T |
0.375 |
|
| 2006 |
Sachs JN, Engelman DM. Introduction to the membrane protein reviews: the interplay of structure, dynamics, and environment in membrane protein function. Annual Review of Biochemistry. 75: 707-12. PMID 16756508 DOI: 10.1146/Annurev.Biochem.75.110105.142336 |
0.372 |
|
| 2005 |
Nanda H, Sachs JN, Petrache HI, Woolf TB. Environmental Effects on Glycophorin A Folding and Structure Examined through Molecular Simulations. Journal of Chemical Theory and Computation. 1: 375-88. PMID 26641504 DOI: 10.1021/Ct049928Y |
0.633 |
|
| 2005 |
Chin CN, Sachs JN, Engelman DM. Transmembrane homodimerization of receptor-like protein tyrosine phosphatases. Febs Letters. 579: 3855-8. PMID 15978577 DOI: 10.1016/J.Febslet.2005.05.071 |
0.418 |
|
| 2005 |
Nanda H, Sachs JN, Petrache HI, Woolf TB. Environmental effects on glycophorin a folding and structure examined through molecular simulations Journal of Chemical Theory and Computation. 1: 375-388. DOI: 10.1021/ct049928y |
0.542 |
|
| 2004 |
Sachs JN, Crozier PS, Woolf TB. Atomistic simulations of biologically realistic transmembrane potential gradients. The Journal of Chemical Physics. 121: 10847-51. PMID 15634036 DOI: 10.1063/1.1826056 |
0.592 |
|
| 2004 |
Sachs JN, Nanda H, Petrache HI, Woolf TB. Changes in phosphatidylcholine headgroup tilt and water order induced by monovalent salts: molecular dynamics simulations. Biophysical Journal. 86: 3772-82. PMID 15189873 DOI: 10.1529/Biophysj.103.035816 |
0.602 |
|
| 2003 |
Sachs JN, Petrache HI, Woolf TB. Interpretation of small angle X-ray measurements guided by molecular dynamics simulations of lipid bilayers. Chemistry and Physics of Lipids. 126: 211-23. PMID 14623455 DOI: 10.1016/J.Chemphyslip.2003.08.001 |
0.598 |
|
| 2003 |
Sachs JN, Woolf TB. Understanding the Hofmeister effect in interactions between chaotropic anions and lipid bilayers: molecular dynamics simulations. Journal of the American Chemical Society. 125: 8742-3. PMID 12862466 DOI: 10.1021/Ja0355729 |
0.634 |
|
| 2003 |
Sachs JN, Petrache HI, Zuckerman DM, Woolf TB. Molecular dynamics simulations of ionic concentration gradients across model bilayers Journal of Chemical Physics. 118: 1957-1969. DOI: 10.1063/1.1531589 |
0.588 |
|
| 2002 |
Petrache HI, Zuckerman DM, Sachs JN, Antoinette Killian J, Koeppe RE, Woolf TB. Hydrophobic matching mechanism investigated by molecular dynamics simulations Langmuir. 18: 1340-1351. DOI: 10.1021/La011338P |
0.64 |
|
| 2002 |
Sachs JN, Woolf TB. Molecular dynamics simulations of charged plates and electrolyte in a bilayer-like geometry: Molecular ordering and electrostatic potential Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 356-357. |
0.535 |
|
| 2000 |
Grossfield A, Sachs J, Woolf TB. Dipole lattice membrane model for protein calculations. Proteins. 41: 211-23. PMID 10966574 DOI: 10.1002/1097-0134(20001101)41:2<211::Aid-Prot60>3.0.Co;2-9 |
0.597 |
|
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