Pablo Celnik - Publications

Johns Hopkins University, Baltimore, MD 

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Uehara S, Mawase F, Therrien AS, Cherry-Allen KM, Celnik PA. Interactions between motor exploration and reinforcement learning. Journal of Neurophysiology. PMID 31242063 DOI: 10.1152/jn.00390.2018  0.88
2019 Schambra HM, Xu J, Branscheidt M, Lindquist M, Uddin J, Steiner L, Hertler B, Kim N, Berard J, Harran MD, Cortes JC, Kitago T, Luft A, Krakauer JW, Celnik PA. Differential Poststroke Motor Recovery in an Arm Versus Hand Muscle in the Absence of Motor Evoked Potentials. Neurorehabilitation and Neural Repair. 1545968319850138. PMID 31170880 DOI: 10.1177/1545968319850138  0.6
2019 Rajan VA, Hardwick RM, Celnik PA. Reciprocal Intralimb Transfer of Skilled Isometric Force Production. Journal of Neurophysiology. PMID 31042443 DOI: 10.1152/jn.00840.2018  0.6
2019 Xu J, Branscheidt M, Schambra H, Steiner L, Widmer M, Diedrichsen J, Goldsmith J, Lindquist M, Kitago T, Luft AR, Krakauer JW, Celnik PA. Rethinking interhemispheric imbalance as a target for stroke neurorehabilitation. Annals of Neurology. PMID 30805956 DOI: 10.1002/ana.25452  0.6
2019 Ejaz N, Xu J, Branscheidt M, Hertler B, Schambra H, Widmer M, Faria AV, Harran M, Cortes JC, Kim N, Celnik PA, Kitago T, Luft A, Krakauer JW, Diedrichsen J. Reply: Further evidence for a non-cortical origin of mirror movements after stroke. Brain : a Journal of Neurology. 142: e2. PMID 30596904 DOI: 10.1093/brain/awy309  0.6
2018 Liew SL, Thompson T, Ramirez J, Butcher PA, Taylor JA, Celnik PA. Variable Neural Contributions to Explicit and Implicit Learning During Visuomotor Adaptation. Frontiers in Neuroscience. 12: 610. PMID 30279645 DOI: 10.3389/fnins.2018.00610  0.36
2018 Salas RME, Kalloo A, Earley CJ, Celnik P, Cruz TE, Foster K, Cantarero G, Allen RP. Connecting clinical aspects to corticomotor excitability in restless legs syndrome: a TMS study. Sleep Medicine. PMID 30170992 DOI: 10.1016/j.sleep.2018.05.002  0.64
2018 Cherry-Allen KM, Statton MA, Celnik PA, Bastian AJ. A Dual-Learning Paradigm Simultaneously Improves Multiple Features of Gait Post-Stroke. Neurorehabilitation and Neural Repair. 1545968318792623. PMID 30086670 DOI: 10.1177/1545968318792623  1
2018 Spampinato D, Celnik P. Deconstructing skill learning and its physiological mechanisms. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 104: 90-102. PMID 29775838 DOI: 10.1016/j.cortex.2018.03.017  0.56
2018 Ejaz N, Xu J, Branscheidt M, Hertler B, Schambra H, Widmer M, Faria AV, Harran MD, Cortes JC, Kim N, Celnik PA, Kitago T, Luft AR, Krakauer JW, Diedrichsen J. Evidence for a subcortical origin of mirror movements after stroke: a longitudinal study. Brain : a Journal of Neurology. PMID 29394326 DOI: 10.1093/brain/awx384  0.6
2017 Hallett M, Di Iorio R, Rossini PM, Park JE, Chen R, Celnik P, Strafella AP, Matsumoto H, Ugawa Y. Contribution of transcranial magnetic stimulation to assessment of brain connectivity and networks. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 128: 2125-2139. PMID 28938143 DOI: 10.1016/j.clinph.2017.08.007  0.44
2017 Xu J, Ejaz N, Hertler B, Branscheidt M, Widmer M, Faria AV, Harran MD, Cortes JC, Kim N, Celnik PA, Kitago T, Luft AR, Krakauer JW, Diedrichsen J. Separable systems for recovery of finger strength and control after stroke. Journal of Neurophysiology. jn.00123.2017. PMID 28566461 DOI: 10.1152/jn.00123.2017  0.6
2017 Cortes JC, Goldsmith J, Harran MD, Xu J, Kim N, Schambra HM, Luft AR, Celnik P, Krakauer JW, Kitago T. A Short and Distinct Time Window for Recovery of Arm Motor Control Early After Stroke Revealed With a Global Measure of Trajectory Kinematics. Neurorehabilitation and Neural Repair. 31: 552-560. PMID 28506149 DOI: 10.1177/1545968317697034  0.6
2017 Buch ER, Santarnecchi E, Antal A, Born J, Celnik PA, Classen J, Gerloff C, Hallett M, Hummel FC, Nitsche MA, Pascual-Leone A, Paulus WJ, Reis J, Robertson EM, Rothwell JC, et al. Effects of tDCS on motor learning and memory formation: A consensus and critical position paper. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 128: 589-603. PMID 28231477 DOI: 10.1016/j.clinph.2017.01.004  0.88
2017 Mawase F, Uehara S, Bastian A, Celnik P. Motor learning enhances use-dependent plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28143961 DOI: 10.1523/JNEUROSCI.3303-16.2017  0.64
2017 Spampinato DA, Block HJ, Celnik PA. Cerebellar-M1 Connectivity Changes Associated with Motor Learning Are Somatotopic Specific. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 2377-2386. PMID 28137969 DOI: 10.1523/JNEUROSCI.2511-16.2017  1
2016 Hardwick RM, Rajan VA, Bastian AJ, Krakauer JW, Celnik PA. Motor Learning in Stroke: Trained Patients Are Not Equal to Untrained Patients With Less Impairment. Neurorehabilitation and Neural Repair. PMID 27789762 DOI: 10.1177/1545968316675432  1
2016 Wymbs NF, Bastian AJ, Celnik PA. Motor Skills Are Strengthened through Reconsolidation. Current Biology : Cb. PMID 26832444 DOI: 10.1016/j.cub.2015.11.066  1
2015 Woods AJ, Antal A, Bikson M, Boggio PS, Brunoni AR, Celnik P, Cohen LG, Fregni F, Herrmann CS, Kappenman ES, Knotkova H, Liebetanz D, Miniussi C, Miranda PC, Paulus W, et al. A technical guide to tDCS, and related non-invasive brain stimulation tools. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. PMID 26652115 DOI: 10.1016/j.clinph.2015.11.012  1
2015 Chae J, Celnik PA. Stroke Rehabilitation. Physical Medicine and Rehabilitation Clinics of North America. 26: xv-xvi. PMID 26522913 DOI: 10.1016/j.pmr.2015.08.013  1
2015 Statton MA, Encarnacion M, Celnik P, Bastian AJ. A Single Bout of Moderate Aerobic Exercise Improves Motor Skill Acquisition. Plos One. 10: e0141393. PMID 26506413 DOI: 10.1371/journal.pone.0141393  1
2015 Lu H, Kobilo T, Robertson C, Tong S, Celnik P, Pelled G. Transcranial magnetic stimulation facilitates neurorehabilitation after pediatric traumatic brain injury. Scientific Reports. 5: 14769. PMID 26440604 DOI: 10.1038/srep14769  1
2015 Cantarero G, Spampinato D, Reis J, Ajagbe L, Thompson T, Kulkarni K, Celnik P. Cerebellar direct current stimulation enhances on-line motor skill acquisition through an effect on accuracy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3285-90. PMID 25698763 DOI: 10.1523/JNEUROSCI.2885-14.2015  1
2015 Hone-Blanchet A, Salas RE, Celnik P, Kalloo A, Schar M, Puts NA, Harris AD, Barker PB, Fecteau S, Earley CJ, Allen RP, Edden RA. Co-registration of magnetic resonance spectroscopy and transcranial magnetic stimulation. Journal of Neuroscience Methods. 242: 52-7. PMID 25561395 DOI: 10.1016/j.jneumeth.2014.12.018  1
2015 Celnik P. Understanding and modulating motor learning with cerebellar stimulation. Cerebellum (London, England). 14: 171-4. PMID 25283180 DOI: 10.1007/s12311-014-0607-y  1
2015 Schlerf JE, Galea JM, Spampinato D, Celnik PA. Laterality Differences in Cerebellar-Motor Cortex Connectivity. Cerebral Cortex (New York, N.Y. : 1991). 25: 1827-34. PMID 24436320 DOI: 10.1093/cercor/bht422  1
2014 Grimaldi G, Argyropoulos GP, Bastian A, Cortes M, Davis NJ, Edwards DJ, Ferrucci R, Fregni F, Galea JM, Hamada M, Manto M, Miall RC, Morales-Quezada L, Pope PA, Priori A, ... ... Celnik P, et al. Cerebellar Transcranial Direct Current Stimulation (ctDCS): A Novel Approach to Understanding Cerebellar Function in Health and Disease. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. PMID 25406224 DOI: 10.1177/1073858414559409  1
2014 Hardwick RM, Celnik PA. Cerebellar direct current stimulation enhances motor learning in older adults. Neurobiology of Aging. 35: 2217-21. PMID 24792908 DOI: 10.1016/j.neurobiolaging.2014.03.030  1
2014 Salas RE, Galea JM, Gamaldo AA, Gamaldo CE, Allen RP, Smith MT, Cantarero G, Lam BD, Celnik PA. Increased use-dependent plasticity in chronic insomnia. Sleep. 37: 535-44. PMID 24587576 DOI: 10.5665/sleep.3492  1
2014 Yau JM, Celnik P, Hsiao SS, Desmond JE. Feeling better: separate pathways for targeted enhancement of spatial and temporal touch. Psychological Science. 25: 555-65. PMID 24390826 DOI: 10.1177/0956797613511467  1
2014 Celnik P, Birmbaumer N. "How much will I recover, doctor?" Some help with an ever-elusive answer. Neurology. 82: 192-3. PMID 24353341 DOI: 10.1212/WNL.0000000000000042  1
2014 Ilg W, Bastian AJ, Boesch S, Burciu RG, Celnik P, Claaßen J, Feil K, Kalla R, Miyai I, Nachbauer W, Schöls L, Strupp M, Synofzik M, Teufel J, Timmann D. Consensus paper: management of degenerative cerebellar disorders. Cerebellum (London, England). 13: 248-68. PMID 24222635 DOI: 10.1007/s12311-013-0531-6  1
2014 Grimaldi G, Argyropoulos GP, Boehringer A, Celnik P, Edwards MJ, Ferrucci R, Galea JM, Groiss SJ, Hiraoka K, Kassavetis P, Lesage E, Manto M, Miall RC, Priori A, Sadnicka A, et al. Non-invasive cerebellar stimulation--a consensus paper. Cerebellum (London, England). 13: 121-38. PMID 23943521 DOI: 10.1007/s12311-013-0514-7  1
2013 Cantarero G, Lloyd A, Celnik P. Reversal of long-term potentiation-like plasticity processes after motor learning disrupts skill retention. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12862-9. PMID 23904621 DOI: 10.1523/JNEUROSCI.1399-13.2013  1
2013 Block H, Celnik P. Stimulating the cerebellum affects visuomotor adaptation but not intermanual transfer of learning. Cerebellum (London, England). 12: 781-93. PMID 23625383 DOI: 10.1007/s12311-013-0486-7  1
2013 Cantarero G, Tang B, O'Malley R, Salas R, Celnik P. Motor learning interference is proportional to occlusion of LTP-like plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4634-41. PMID 23486938 DOI: 10.1523/JNEUROSCI.4706-12.2013  1
2013 Block H, Bastian A, Celnik P. Virtual lesion of angular gyrus disrupts the relationship between visuoproprioceptive weighting and realignment. Journal of Cognitive Neuroscience. 25: 636-48. PMID 23249345 DOI: 10.1162/jocn_a_00340  1
2013 Humbert IA, Christopherson H, Lokhande A, German R, Gonzalez-Fernandez M, Celnik P. Human hyolaryngeal movements show adaptive motor learning during swallowing. Dysphagia. 28: 139-45. PMID 22926828 DOI: 10.1007/s00455-012-9422-0  1
2012 Block HJ, Celnik P. Can cerebellar transcranial direct current stimulation become a valuable neurorehabilitation intervention? Expert Review of Neurotherapeutics. 12: 1275-7. PMID 23234389 DOI: 10.1586/ern.12.121  1
2012 Schlerf JE, Galea JM, Bastian AJ, Celnik PA. Dynamic modulation of cerebellar excitability for abrupt, but not gradual, visuomotor adaptation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11610-7. PMID 22915105 DOI: 10.1523/JNEUROSCI.1609-12.2012  1
2012 Jayaram G, Tang B, Pallegadda R, Vasudevan EV, Celnik P, Bastian A. Modulating locomotor adaptation with cerebellar stimulation. Journal of Neurophysiology. 107: 2950-7. PMID 22378177 DOI: 10.1152/jn.00645.2011  1
2011 Hoyer EH, Celnik PA. Understanding and enhancing motor recovery after stroke using transcranial magnetic stimulation. Restorative Neurology and Neuroscience. 29: 395-409. PMID 22124033 DOI: 10.3233/RNN-2011-0611  1
2011 Cantarero G, Galea JM, Ajagbe L, Salas R, Willis J, Celnik P. Disrupting the ventral premotor cortex interferes with the contribution of action observation to use-dependent plasticity. Journal of Cognitive Neuroscience. 23: 3757-66. PMID 21563888 DOI: 10.1162/jocn_a_00051  1
2011 Orban de Xivry JJ, Marko MK, Pekny SE, Pastor D, Izawa J, Celnik P, Shadmehr R. Stimulation of the human motor cortex alters generalization patterns of motor learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7102-10. PMID 21562272 DOI: 10.1523/JNEUROSCI.0273-11.2011  1
2011 Jayaram G, Galea JM, Bastian AJ, Celnik P. Human locomotor adaptive learning is proportional to depression of cerebellar excitability. Cerebral Cortex (New York, N.Y. : 1991). 21: 1901-9. PMID 21239392 DOI: 10.1093/cercor/bhq263  1
2011 Galea JM, Vazquez A, Pasricha N, de Xivry JJ, Celnik P. Dissociating the roles of the cerebellum and motor cortex during adaptive learning: the motor cortex retains what the cerebellum learns. Cerebral Cortex (New York, N.Y. : 1991). 21: 1761-70. PMID 21139077 DOI: 10.1093/cercor/bhq246  1
2010 Hummel FC, Heise K, Celnik P, Floel A, Gerloff C, Cohen LG. Facilitating skilled right hand motor function in older subjects by anodal polarization over the left primary motor cortex. Neurobiology of Aging. 31: 2160-8. PMID 19201066 DOI: 10.1016/j.neurobiolaging.2008.12.008  1
2009 Celnik P, Hillis AE. Reconnecting the dots after stroke. Annals of Neurology. 66: 570-1. PMID 19938067 DOI: 10.1002/ana.21811  1
2009 Galea JM, Jayaram G, Ajagbe L, Celnik P. Modulation of cerebellar excitability by polarity-specific noninvasive direct current stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9115-22. PMID 19605648 DOI: 10.1523/JNEUROSCI.2184-09.2009  1
2009 Galea JM, Celnik P. Brain polarization enhances the formation and retention of motor memories. Journal of Neurophysiology. 102: 294-301. PMID 19386757 DOI: 10.1152/jn.00184.2009  1
2009 Celnik P, Paik NJ, Vandermeeren Y, Dimyan M, Cohen LG. Effects of combined peripheral nerve stimulation and brain polarization on performance of a motor sequence task after chronic stroke. Stroke; a Journal of Cerebral Circulation. 40: 1764-71. PMID 19286579 DOI: 10.1161/STROKEAHA.108.540500  1
2009 Makley MJ, Johnson-Greene L, Tarwater PM, Kreuz AJ, Spiro J, Rao V, Celnik PA. Return of memory and sleep efficiency following moderate to severe closed head injury. Neurorehabilitation and Neural Repair. 23: 320-6. PMID 19171947 DOI: 10.1177/1545968308325268  1
2009 Reis J, Schambra HM, Cohen LG, Buch ER, Fritsch B, Zarahn E, Celnik PA, Krakauer JW. Noninvasive cortical stimulation enhances motor skill acquisition over multiple days through an effect on consolidation. Proceedings of the National Academy of Sciences of the United States of America. 106: 1590-5. PMID 19164589 DOI: 10.1073/pnas.0805413106  1
2008 Hummel FC, Celnik P, Pascual-Leone A, Fregni F, Byblow WD, Buetefisch CM, Rothwell J, Cohen LG, Gerloff C. Controversy: Noninvasive and invasive cortical stimulation show efficacy in treating stroke patients. Brain Stimulation. 1: 370-82. PMID 20633395 DOI: 10.1016/j.brs.2008.09.003  1
2008 Reis J, Robertson EM, Krakauer JW, Rothwell J, Marshall L, Gerloff C, Wassermann EM, Pascual-Leone A, Hummel F, Celnik PA, Classen J, Floel A, Ziemann U, Paulus W, Siebner HR, et al. Consensus: Can transcranial direct current stimulation and transcranial magnetic stimulation enhance motor learning and memory formation? Brain Stimulation. 1: 363-9. PMID 20633394 DOI: 10.1016/j.brs.2008.08.001  0.88
2008 Reis J, Robertson E, Krakauer JW, Rothwell J, Marshall L, Gerloff C, Wassermann E, Pascual-Leone A, Hummel F, Celnik PA, Classen J, Floel A, Ziemann U, Paulus W, Siebner HR, et al. Consensus: "Can tDCS and TMS enhance motor learning and memory formation?" Brain Stimulation. 1: 363-369. PMID 19802336 DOI: 10.1016/j.brs.2008.08.001  1
2008 Makley MJ, English JB, Drubach DA, Kreuz AJ, Celnik PA, Tarwater PM. Prevalence of sleep disturbance in closed head injury patients in a rehabilitation unit. Neurorehabilitation and Neural Repair. 22: 341-7. PMID 18663247 DOI: 10.1177/1545968308315598  1
2008 Celnik P, Webster B, Glasser DM, Cohen LG. Effects of action observation on physical training after stroke. Stroke; a Journal of Cerebral Circulation. 39: 1814-20. PMID 18403746 DOI: 10.1161/STROKEAHA.107.508184  1
2008 Stefan K, Classen J, Celnik P, Cohen LG. Concurrent action observation modulates practice-induced motor memory formation. The European Journal of Neuroscience. 27: 730-8. PMID 18279325 DOI: 10.1111/j.1460-9568.2008.06035.x  1
2007 Celnik P, Hummel F, Harris-Love M, Wolk R, Cohen LG. Somatosensory stimulation enhances the effects of training functional hand tasks in patients with chronic stroke. Archives of Physical Medicine and Rehabilitation. 88: 1369-76. PMID 17964875 DOI: 10.1016/j.apmr.2007.08.001  1
2007 Duque J, Murase N, Celnik P, Hummel F, Harris-Love M, Mazzocchio R, Olivier E, Cohen LG. Intermanual Differences in movement-related interhemispheric inhibition. Journal of Cognitive Neuroscience. 19: 204-13. PMID 17280510 DOI: 10.1162/jocn.2007.19.2.204  1
2006 Hummel FC, Voller B, Celnik P, Floel A, Giraux P, Gerloff C, Cohen LG. Effects of brain polarization on reaction times and pinch force in chronic stroke. Bmc Neuroscience. 7: 73. PMID 17083730 DOI: 10.1186/1471-2202-7-73  1
2006 Webster BR, Celnik PA, Cohen LG. Noninvasive brain stimulation in stroke rehabilitation. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 3: 474-81. PMID 17012061 DOI: 10.1016/j.nurx.2006.07.008  1
2006 Celnik P, Stefan K, Hummel F, Duque J, Classen J, Cohen LG. Encoding a motor memory in the older adult by action observation. Neuroimage. 29: 677-84. PMID 16125417 DOI: 10.1016/j.neuroimage.2005.07.039  1
2005 Stefan K, Cohen LG, Duque J, Mazzocchio R, Celnik P, Sawaki L, Ungerleider L, Classen J. Formation of a motor memory by action observation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9339-46. PMID 16221842 DOI: 10.1523/JNEUROSCI.2282-05.2005  1
2005 Duque J, Hummel F, Celnik P, Murase N, Mazzocchio R, Cohen LG. Transcallosal inhibition in chronic subcortical stroke. Neuroimage. 28: 940-6. PMID 16084737 DOI: 10.1016/j.neuroimage.2005.06.033  1
2005 Flöel A, Breitenstein C, Hummel F, Celnik P, Gingert C, Sawaki L, Knecht S, Cohen LG. Dopaminergic influences on formation of a motor memory. Annals of Neurology. 58: 121-30. PMID 15984008 DOI: 10.1002/ana.20536  1
2005 Hummel F, Celnik P, Giraux P, Floel A, Wu WH, Gerloff C, Cohen LG. Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke. Brain : a Journal of Neurology. 128: 490-9. PMID 15634731 DOI: 10.1093/brain/awh369  1
2004 Celnik PA, Cohen LG. Modulation of motor function and cortical plasticity in health and disease. Restorative Neurology and Neuroscience. 22: 261-8. PMID 15502270  1
2000 Liepert J, Hallett M, Samii A, Oddo D, Celnik P, Cohen LG, Wassermann EM. Motor cortex excitability in patients with cerebellar degeneration. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 111: 1157-64. PMID 10880788 DOI: 10.1016/S1388-2457(00)00308-4  1
2000 Classen J, Steinfelder B, Liepert J, Stefan K, Celnik P, Cohen LG, Hess A, Kunesch E, Chen R, Benecke R, Hallett M. Cutaneomotor integration in humans is somatotopically organized at various levels of the nervous system and is task dependent. Experimental Brain Research. 130: 48-59. PMID 10638440  1
1999 Cohen LG, Weeks RA, Sadato N, Celnik P, Ishii K, Hallett M. Period of susceptibility for cross-modal plasticity in the blind. Annals of Neurology. 45: 451-60. PMID 10211469 DOI: 10.1002/1531-8249(199904)45:4<451::AID-ANA6>3.0.CO;2-B  1
1997 Cohen LG, Celnik P, Pascual-Leone A, Corwell B, Falz L, Dambrosia J, Honda M, Sadato N, Gerloff C, Catalá MD, Hallett M. Functional relevance of cross-modal plasticity in blind humans. Nature. 389: 180-3. PMID 9296495 DOI: 10.1038/38278  1
1997 Chen R, Classen J, Gerloff C, Celnik P, Wassermann EM, Hallett M, Cohen LG. Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation. Neurology. 48: 1398-403. PMID 9153480  1
1996 Zeilig G, Katz-Zeilig M, Celnik PA, Drubach DA. Metastatic and traumatic spinal cord injury: Acute rehabilitation outcome, post-discharge placement, and one year survival Neurorehabilitation and Neural Repair. 10: 59-63. DOI: 10.1177/154596839601000110  1
1995 Bonamico L, Celnik P. Syncope and seizure-like activity secondary to acute herpes zoster infection of the trigeminal nerve. Cephalalgia : An International Journal of Headache. 15: 241-2. PMID 7553816  1
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