| Year |
Citation |
Score |
| 2024 |
Schillo JL, Feddersen CR, Peplinski RM, Powell LS, Varzavand A, Stipp CS, Riordan JD, Dupuy AJ. Single-cell genomics analysis reveals complex genetic interactions in an model of acquired BRAF inhibitor resistance. Nar Cancer. 6: zcad061. PMID 38213996 DOI: 10.1093/narcan/zcad061 |
0.711 |
|
| 2023 |
Zhu EY, Schillo JL, Murray SD, Riordan JD, Dupuy AJ. Understanding cancer drug resistance with functional genomic screens: Application to MAPK inhibition in cutaneous melanoma. Iscience. 26: 107805. PMID 37860756 DOI: 10.1016/j.isci.2023.107805 |
0.702 |
|
| 2022 |
Zhu EY, Riordan JD, Vanneste M, Henry MD, Stipp CS, Dupuy AJ. SRC-RAC1 signaling drives drug resistance to BRAF inhibition in de-differentiated cutaneous melanomas. Npj Precision Oncology. 6: 74. PMID 36271142 DOI: 10.1038/s41698-022-00310-7 |
0.693 |
|
| 2022 |
Li Y, Zhou W, Meng X, Murray SD, Li L, Fronk A, Lazaro-Camp VJ, Wen KK, Wu M, Dupuy A, Leslie KK, Yang S. Utilizing an Endogenous Progesterone Receptor Reporter Gene for Drug Screening and Mechanistic Study in Endometrial Cancer. Cancers. 14. PMID 36230806 DOI: 10.3390/cancers14194883 |
0.324 |
|
| 2021 |
Sun F, Cheng Y, Riordan JD, Dupuy A, Dubois W, Pisano M, Dong J, Mock B, Zhan F, Hari P, Janz S. WDR26 and MTF2 are therapeutic targets in multiple myeloma. Journal of Hematology & Oncology. 14: 203. PMID 34876184 DOI: 10.1186/s13045-021-01217-9 |
0.744 |
|
| 2021 |
Schachter NF, Adams JR, Skowron P, Kozma KJ, Lee CA, Raghuram N, Yang J, Loch AJ, Wang W, Kucharczuk A, Wright KL, Quintana RM, An Y, Dotzko D, Gorman JL, ... ... Dupuy AJ, et al. Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer. Nature Communications. 12: 5238. PMID 34475389 DOI: 10.1038/s41467-021-25467-w |
0.322 |
|
| 2020 |
Rogers LM, Wang Z, Mott SL, Dupuy AJ, Weiner GJ. A genetic screen to identify gain- and loss-of-function modifications that enhance T-cell infiltration into tumors. Cancer Immunology Research. PMID 32611665 DOI: 10.1158/2326-6066.Cir-20-0056 |
0.633 |
|
| 2020 |
Vanneste M, Feddersen CR, Varzavand A, Zhu EY, Foley T, Zhao L, Holt KH, Milhem M, Piper R, Stipp CS, Dupuy AJ, Henry MD. Functional Genomic Screening Independently Identifies CUL3 as a Mediator of Vemurafenib Resistance via Src-Rac1 Signaling Axis. Frontiers in Oncology. 10: 442. PMID 32346533 DOI: 10.3389/Fonc.2020.00442 |
0.354 |
|
| 2020 |
Rogers LM, Dupuy AJ, Weiner GJ. Abstract A51: Rationally improving T cell-mediated cancer immunotherapies using Sleeping Beauty mutagenesis to identify novel therapeutic targets Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-A51 |
0.646 |
|
| 2019 |
Tompkins SC, Sheldon RD, Rauckhorst AJ, Noterman MF, Solst SR, Buchanan JL, Mapuskar KA, Pewa AD, Gray LR, Oonthonpan L, Sharma A, Scerbo DA, Dupuy AJ, Spitz DR, Taylor EB. Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis. Cell Reports. 28: 2608-2619.e6. PMID 31484072 DOI: 10.1016/J.Celrep.2019.07.098 |
0.36 |
|
| 2019 |
Feddersen CR, Schillo JL, Varzavand A, Vaughn HR, Wadsworth LS, Voigt AP, Zhu EY, Jennings BM, Mullen SA, Bobera J, Riordan JD, Stipp CS, Dupuy AJ. Src-dependent DBL family members drive resistance to vemurafenib in human melanoma. Cancer Research. PMID 31416844 DOI: 10.1158/0008-5472.Can-19-0244 |
0.703 |
|
| 2019 |
Guimaraes-Young A, Feddersen CR, Dupuy AJ. Sleeping Beauty Mouse Models of Cancer: Microenvironmental Influences on Cancer Genetics. Frontiers in Oncology. 9: 611. PMID 31338332 DOI: 10.3389/Fonc.2019.00611 |
0.426 |
|
| 2019 |
Feddersen CR, Wadsworth LS, Zhu EY, Vaughn HR, Voigt AP, Riordan JD, Dupuy AJ. A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells. Bmc Genomics. 20: 497. PMID 31208320 DOI: 10.1186/S12864-019-5888-6 |
0.712 |
|
| 2019 |
Loeb KR, Hughes BT, Fissel BM, Osteen NJ, Knoblaugh SE, Grim JE, Drury LJ, Sarver A, Dupuy AJ, Clurman BE. Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice. Scientific Reports. 9: 5488. PMID 30940846 DOI: 10.1038/S41598-019-41805-X |
0.425 |
|
| 2018 |
Merritt NM, Fullenkamp CA, Hall SL, Qian Q, Desai C, Thomason J, Lambertz AM, Dupuy AJ, Darbro B, Tanas MR. A comprehensive evaluation of Hippo pathway silencing in sarcomas. Oncotarget. 9: 31620-31636. PMID 30167083 DOI: 10.18632/Oncotarget.25824 |
0.335 |
|
| 2018 |
Ziyad S, Riordan JD, Cavanaugh AM, Su T, Hernandez GE, Hilfenhaus G, Morselli M, Huynh K, Wang K, Chen JN, Dupuy AJ, Iruela-Arispe ML. A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis. Cell Reports. 22: 1211-1224. PMID 29386109 DOI: 10.1016/J.Celrep.2018.01.017 |
0.736 |
|
| 2018 |
Li Y, Meng X, Wen K, Wu M, Dupuy A, Leslie K, Yang S. Abstract 2494: A novel tool for monitoring endogenous progesterone receptor expression by mCherry using CRISPR-Cas9 genome editing technique Cancer Research. 78: 2494-2494. DOI: 10.1158/1538-7445.Am2018-2494 |
0.424 |
|
| 2017 |
Tschida BR, Temiz NA, Kuka TP, Lee LA, Riordan JD, Tierrablanca CA, Hullsiek R, Wagner S, Hudson WA, Linden MA, Amin K, Beckmann PJ, Heuer RA, Sarver AL, Yang JD, ... ... Dupuy AJ, et al. Sleeping Beauty insertional mutagenesis in mice identifies drivers of steatosis-associated hepatic tumor. Cancer Research. PMID 28993411 DOI: 10.1158/0008-5472.Can-17-2281 |
0.731 |
|
| 2017 |
Riordan JD, Feddersen CR, Tschida BR, Jackson P, Keng VW, Linden MA, Amin K, Stipp CS, Largaespada DA, Dupuy AJ. Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma. Hepatology (Baltimore, Md.). PMID 28961327 DOI: 10.1002/Hep.29565 |
0.721 |
|
| 2017 |
Montero-Conde C, Leandro-Garcia LJ, Chen X, Oler G, Ruiz-Llorente S, Ryder M, Landa I, Sanchez-Vega F, La K, Ghossein RA, Bajorin DF, Knauf JA, Riordan JD, Dupuy AJ, Fagin JA. Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene. Proceedings of the National Academy of Sciences of the United States of America. PMID 28584132 DOI: 10.1073/Pnas.1702723114 |
0.748 |
|
| 2017 |
Suárez-Cabrera C, Quintana RM, Bravo A, Casanova ML, Page A, Alameda JP, Paramio JM, Maroto A, Salamanca J, Dupuy AJ, Ramírez A, Navarro M. A transposon-based analysis reveals RASA1 is involved in triple negative breast cancer. Cancer Research. PMID 28108518 DOI: 10.1158/0008-5472.Can-16-1586 |
0.393 |
|
| 2016 |
Morris SM, Davison J, Carter KT, O'Leary RM, Trobridge P, Knoblaugh SE, Myeroff LL, Markowitz SD, Brett BT, Scheetz TE, Dupuy AJ, Starr TK, Grady WM. Transposon mutagenesis identifies candidate genes that cooperate with loss of Transforming Growth Factor-beta signaling in mouse intestinal neoplasms. International Journal of Cancer. PMID 27790711 DOI: 10.1002/Ijc.30491 |
0.399 |
|
| 2016 |
Sun Z, Yu W, Navarro MS, Sweat M, Eliason S, Sharp T, Liu H, Seidel K, Zhang L, Moreno M, Lynch T, Holton NE, Rogers L, Neff T, Goodheart MJ, ... ... Dupuy A, et al. Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal. Development (Cambridge, England). PMID 27660324 DOI: 10.1242/Dev.138883 |
0.569 |
|
| 2016 |
Guimarães-Young A, Neff T, Dupuy AJ, Goodheart MJ. Conditional deletion of Sox17 reveals complex effects on uterine adenogenesis and function. Developmental Biology. PMID 27102016 DOI: 10.1016/J.Ydbio.2016.04.010 |
0.323 |
|
| 2016 |
Morrissy AS, Garzia L, Shih DJ, Zuyderduyn S, Huang X, Skowron P, Remke M, Cavalli FM, Ramaswamy V, Lindsay PE, Jelveh S, Donovan LK, Wang X, Luu B, Zayne K, ... ... Dupuy AJ, et al. Divergent clonal selection dominates medulloblastoma at recurrence. Nature. PMID 26760213 DOI: 10.1038/Nature16478 |
0.338 |
|
| 2016 |
Rogers LM, Dupuy AJ, Weiner GJ. Abstract 526: Identification of novel cancer immunotherapy targets using Sleeping Beauty mutagenesis Immunology. 76: 526-526. DOI: 10.1158/1538-7445.Am2016-526 |
0.591 |
|
| 2016 |
Feddersen CR, Dupuy AJ. Abstract 4378: Discovery and characterization of two novel drivers of hepatocellular carcinoma Cancer Research. 76: 4378-4378. DOI: 10.1158/1538-7445.Am2016-4378 |
0.489 |
|
| 2015 |
Temiz NA, Moriarity BS, Wolf NK, Riordan JD, Dupuy AJ, Largaespada DA, Sarver AL. RNA sequencing of Sleeping Beauty transposon-induced tumors detect transposon-RNA fusions allowing precision analyses of forward genetic cancer screens. Genome Research. PMID 26553456 DOI: 10.1101/Gr.188649.114 |
0.717 |
|
| 2015 |
Mann MB, Black MA, Jones DJ, Ward JM, Yew CC, Newberg JY, Dupuy AJ, Rust AG, Bosenberg MW, McMahon M, Print CG, Copeland NG, Jenkins NA. Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma. Nature Genetics. 47: 486-95. PMID 25848750 DOI: 10.1038/Ng.3275 |
0.446 |
|
| 2015 |
Smith RP, Riordan JD, Feddersen CR, Dupuy AJ. A Hybrid Adenoviral Vector System Achieves Efficient Long-Term Gene Expression in the Liver via piggyBac Transposition. Human Gene Therapy. 26: 377-85. PMID 25808258 DOI: 10.1089/Hum.2014.123 |
0.71 |
|
| 2015 |
Thiel WH, Thiel KW, Flenker KS, Bair T, Dupuy AJ, McNamara JO, Miller FJ, Giangrande PH. Cell-internalization SELEX: method for identifying cell-internalizing RNA aptamers for delivering siRNAs to target cells. Methods in Molecular Biology (Clifton, N.J.). 1218: 187-99. PMID 25319652 DOI: 10.1007/978-1-4939-1538-5_11 |
0.311 |
|
| 2015 |
Guimaraes-Young A, Neff T, Meyerholz DK, Dupuy AJ, Goodheart MJ. Abstract 4192: Identification of novel genetic drivers of vulvar carcinoma in a Sleeping Beauty model of spontaneous cancer Cancer Research. 75: 4192-4192. DOI: 10.1158/1538-7445.Am2015-4192 |
0.516 |
|
| 2015 |
Stephan J, Neff T, Dupuy A, Goodheart M. A distinct gene expression signature in uterine and ovarian tumors suggests different biological pathways in the serous subtype independent of tissue of origin Gynecologic Oncology. 139: 187-188. DOI: 10.1016/J.Ygyno.2015.07.043 |
0.372 |
|
| 2014 |
Riordan JD, Drury LJ, Smith RP, Brett BT, Rogers LM, Scheetz TE, Dupuy AJ. Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens. Bmc Genomics. 15: 1150. PMID 25526783 DOI: 10.1186/1471-2164-15-1150 |
0.779 |
|
| 2014 |
Gibson-Corley KN, Rogers LM, Goeken A, Dupuy AJ, Meyerholz DK. Keratoacanthoma Pathobiology in Mouse Models. Diseases (Basel, Switzerland). 2: 106-119. PMID 25309748 DOI: 10.3390/Diseases2020106 |
0.588 |
|
| 2014 |
Zhang Z, Kim K, Li X, Moreno M, Sharp T, Goodheart MJ, Safe S, Dupuy AJ, Amendt BA. MicroRNA-26b represses colon cancer cell proliferation by inhibiting lymphoid enhancer factor 1 expression. Molecular Cancer Therapeutics. 13: 1942-51. PMID 24785257 DOI: 10.1158/1535-7163.Mct-13-1000 |
0.418 |
|
| 2014 |
Bard-Chapeau EA, Nguyen AT, Rust AG, Sayadi A, Lee P, Chua BQ, New LS, de Jong J, Ward JM, Chin CK, Chew V, Toh HC, Abastado JP, Benoukraf T, Soong R, ... ... Dupuy AJ, et al. Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model. Nature Genetics. 46: 24-32. PMID 24316982 DOI: 10.1038/Ng.2847 |
0.39 |
|
| 2014 |
Lim L, Balakrishnan A, Huskey N, Jones KD, Jodari M, Ng R, Song G, Riordan J, Anderton B, Cheung ST, Willenbring H, Dupuy A, Chen X, Brown D, Chang AN, et al. MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer. Hepatology (Baltimore, Md.). 59: 202-15. PMID 23913442 DOI: 10.1002/Hep.26662 |
0.712 |
|
| 2014 |
Ziyad S, Riordan J, Huynh K, Brett B, Scheetz T, Dupuy A, Iruela-Arispe M. Endothelial cell mutagenesis during development yields hematopoietic abnormalities Experimental Hematology. 42: S67. DOI: 10.1016/J.Exphem.2014.07.258 |
0.661 |
|
| 2013 |
DeZwaan-McCabe D, Riordan JD, Arensdorf AM, Icardi MS, Dupuy AJ, Rutkowski DT. The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis. Plos Genetics. 9: e1003937. PMID 24367269 DOI: 10.1371/Journal.Pgen.1003937 |
0.726 |
|
| 2013 |
Riordan JD, Dupuy AJ. Domesticated transposable element gene products in human cancer. Mobile Genetic Elements. 3: e26693. PMID 24251072 DOI: 10.4161/Mge.26693 |
0.737 |
|
| 2013 |
Riordan JD, Keng VW, Tschida BR, Scheetz TE, Bell JB, Podetz-Pedersen KM, Moser CD, Copeland NG, Jenkins NA, Roberts LR, Largaespada DA, Dupuy AJ. Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis. Plos Genetics. 9: e1003441. PMID 23593033 DOI: 10.1371/Journal.Pgen.1003441 |
0.754 |
|
| 2013 |
Zanesi N, Balatti V, Riordan J, Burch A, Rizzotto L, Palamarchuk A, Cascione L, Lagana A, Dupuy AJ, Croce CM, Pekarsky Y. A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model. Blood. 121: 4355-8. PMID 23591791 DOI: 10.1182/Blood-2013-02-486035 |
0.745 |
|
| 2013 |
Rogers LM, Olivier AK, Meyerholz DK, Dupuy AJ. Adaptive immunity does not strongly suppress spontaneous tumors in a Sleeping Beauty model of cancer. Journal of Immunology (Baltimore, Md. : 1950). 190: 4393-9. PMID 23475219 DOI: 10.4049/Jimmunol.1203227 |
0.622 |
|
| 2013 |
Rogers LM, Riordan JD, Swick BL, Meyerholz DK, Dupuy AJ. Ectopic expression of Zmiz1 induces cutaneous squamous cell malignancies in a mouse model of cancer. The Journal of Investigative Dermatology. 133: 1863-9. PMID 23426136 DOI: 10.1038/Jid.2013.77 |
0.78 |
|
| 2013 |
Keng VW, Sia D, Sarver AL, Tschida BR, Fan D, Alsinet C, Solé M, Lee WL, Kuka TP, Moriarity BS, Villanueva A, Dupuy AJ, Riordan JD, Bell JB, Silverstein KA, et al. Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR. Hepatology (Baltimore, Md.). 57: 120-30. PMID 22899566 DOI: 10.1002/Hep.26004 |
0.739 |
|
| 2013 |
Quintana RM, Dupuy AJ, Bravo A, Casanova ML, Alameda JP, Page A, Sánchez-Viera M, Ramírez A, Navarro M. A transposon-based analysis of gene mutations related to skin cancer development. The Journal of Investigative Dermatology. 133: 239-48. PMID 22832494 DOI: 10.1038/Jid.2012.245 |
0.507 |
|
| 2013 |
Stephan J, Neff T, Bair T, Park S, Bender D, Ahmed A, De Geest K, Dupuy A, Goodheart M. Endometrioid ovarian carcinoma has a distinct gene expression profile separate and unique from serous ovarian carcinoma Gynecologic Oncology. 130: e133. DOI: 10.1016/J.Ygyno.2013.04.380 |
0.348 |
|
| 2012 |
Mann KM, Ward JM, Yew CC, Kovochich A, Dawson DW, Black MA, Brett BT, Sheetz TE, Dupuy AJ, Chang DK, Biankin AV, Waddell N, Kassahn KS, Grimmond SM, et al. Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma. Proceedings of the National Academy of Sciences of the United States of America. 109: 5934-41. PMID 22421440 DOI: 10.1073/Pnas.1202490109 |
0.455 |
|
| 2012 |
Berquam-Vrieze KE, Swing DA, Tessarollo L, Dupuy AJ. Characterization of transgenic mice expressing cancer-associated variants of human NOTCH1. Genesis (New York, N.Y. : 2000). 50: 112-8. PMID 21898766 DOI: 10.1002/Dvg.20798 |
0.352 |
|
| 2012 |
Drury L, Brett B, Sheetz T, Dupuy AJ. Characterization of T-Cell Lymphoblastic Leukemia Genetic Etiology Blood. 120: 5128-5128. DOI: 10.1182/Blood.V120.21.5128.5128 |
0.407 |
|
| 2012 |
Lifton S, Olivier A, Dupuy A, Dubois W, Wolff L, Janz S. Abstract A8: Network analysis of retroviral and transposon mutagenesis sites in B cell lymphoma converges on MyD88 pathway Cancer Research. 72. DOI: 10.1158/1538-7445.Csb12-A8 |
0.352 |
|
| 2012 |
Nadkarni NJ, Rogers L, Samuelson M, Neff T, Bender DP, Ahmed A, Geest KD, Button A, Dupuy A, Goodheart MJ. Abstract 1192: ZMIZ1 is elevated in epithelial ovarian cancer due to an upregulated alternative promoter and is associated with p53 mutations Cancer Research. 72: 1192-1192. DOI: 10.1158/1538-7445.Am2012-1192 |
0.417 |
|
| 2011 |
Brett BT, Berquam-Vrieze KE, Nannapaneni K, Huang J, Scheetz TE, Dupuy AJ. Novel molecular and computational methods improve the accuracy of insertion site analysis in Sleeping Beauty-induced tumors. Plos One. 6: e24668. PMID 21931803 DOI: 10.1371/Journal.Pone.0024668 |
0.461 |
|
| 2011 |
Berquam-Vrieze KE, Nannapaneni K, Brett BT, Holmfeldt L, Ma J, Zagorodna O, Jenkins NA, Copeland NG, Meyerholz DK, Knudson CM, Mullighan CG, Scheetz TE, Dupuy AJ. Cell of origin strongly influences genetic selection in a mouse model of T-ALL. Blood. 118: 4646-56. PMID 21828136 DOI: 10.1182/Blood-2011-03-343947 |
0.466 |
|
| 2011 |
McGrail M, Hatler JM, Kuang X, Liao HK, Nannapaneni K, Watt KE, Uhl JD, Largaespada DA, Vollbrecht E, Scheetz TE, Dupuy AJ, Hostetter JM, Essner JJ. Somatic mutagenesis with a Sleeping Beauty transposon system leads to solid tumor formation in zebrafish. Plos One. 6: e18826. PMID 21533036 DOI: 10.1371/Journal.Pone.0018826 |
0.465 |
|
| 2011 |
Starr TK, Scott PM, Marsh BM, Zhao L, Than BL, O'Sullivan MG, Sarver AL, Dupuy AJ, Largaespada DA, Cormier RT. A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 5765-70. PMID 21436051 DOI: 10.1073/Pnas.1018012108 |
0.457 |
|
| 2011 |
Nadkarni N, Rogers L, Samuelson M, Neff T, Bender D, Ahmed A, De Geest K, Button A, Dupuy A, Goodheart M. Zmiz1 is overexpressed in epithelial ovarian cancer and associated with p53 gene mutations Gynecologic Oncology. 123: 446-447. DOI: 10.1016/J.Ygyno.2011.07.084 |
0.647 |
|
| 2011 |
Riordan JD, Rogers LM, Berquam-Vrieze KE, Dupuy AJ. Sleeping beauty models of cancer Insertional Mutagenesis Strategies in Cancer Genetics. 113-130. DOI: 10.1007/978-1-4419-7656-7_5 |
0.733 |
|
| 2011 |
Dupuy AJ, Largaespada DA. Insertional mutagenesis strategies in cancer genetics Insertional Mutagenesis Strategies in Cancer Genetics. 1-200. DOI: 10.1007/978-1-4419-7656-7 |
0.325 |
|
| 2010 |
Dupuy AJ. Current applications of transposons in mouse genetics. Methods in Enzymology. 477: 53-70. PMID 20699136 DOI: 10.1016/S0076-6879(10)77004-X |
0.347 |
|
| 2010 |
Dupuy AJ. Transposon-based screens for cancer gene discovery in mouse models. Seminars in Cancer Biology. 20: 261-8. PMID 20478384 DOI: 10.1016/J.Semcancer.2010.05.003 |
0.485 |
|
| 2010 |
Wang DH, Clemons NJ, Miyashita T, Dupuy AJ, Zhang W, Szczepny A, Corcoran-Schwartz IM, Wilburn DL, Montgomery EA, Wang JS, Jenkins NA, Copeland NA, Harmon JW, Phillips WA, Watkins DN. Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasia. Gastroenterology. 138: 1810-22. PMID 20138038 DOI: 10.1053/J.Gastro.2010.01.048 |
0.377 |
|
| 2010 |
Wu X, Collier L, Northcott P, Dubuc A, Eberhart C, Meter TV, Zagzag D, Croul S, Dupuy A, Scheetz TE, Scherer S, Bouffet E, Weiss WA, Largaespada DAD, Taylor MD. Abstract 4350: Clonal selection and parallel evolution during leptomeningeal dissemination of human and mouse medulloblastoma result in bicompartmental disease Cancer Research. 70: 4350-4350. DOI: 10.1158/1538-7445.Am10-4350 |
0.412 |
|
| 2010 |
Keng VW, Ryan BJ, Silverstein KAT, Sarver A, Fan D, Dupuy AJ, Jenkins NA, Copeland NG, Largaespada DA. Abstract 4182: A screen for genes that define the strong gender bias nature of hepatocellular carcinoma using a transposon mutagenesis murine model Cancer Research. 70: 4182-4182. DOI: 10.1158/1538-7445.Am10-4182 |
0.468 |
|
| 2010 |
Rogers LM, Swick BL, Meyerholz DK, Dupuy AJ. Abstract 249: A Sleeping Beauty screen in mice identifies Zmiz1 as a candidate cancer gene in human squamous cell carcinomas Cellular and Molecular Biology. 70: 249-249. DOI: 10.1158/1538-7445.Am10-249 |
0.654 |
|
| 2010 |
Riordan JD, Keng VW, Ryan BJ, Podetz-Pedersen KM, Copeland NG, Jenkins NA, Largaespada DA, Dupuy AJ. Abstract 236: Sleeping Beauty transposon integration within the Dlk1-Dio3 imprinted domain is associated with hepatocellular carcinoma development Cancer Research. 70: 236-236. DOI: 10.1158/1538-7445.Am10-236 |
0.745 |
|
| 2010 |
Largaespada DA, Rahrmann EP, Keng VW, Clark HB, Dupuy AJ, Tessarollo L, Jenkins NA, Copeland NG, Ratner N. Abstract 2199: A murine insertional mutagenesis screen to identify oncogenes and tumor suppressor genes involved in Schwann cell tumorigenesis Cancer Research. 70: 2199-2199. DOI: 10.1158/1538-7445.Am10-2199 |
0.457 |
|
| 2010 |
Berquam-Vrieze KE, Nannapaneni K, Zagorodna O, Mullighan C, Meyerholz DK, Copeland N, Jenkins N, Knudson CM, Scheetz T, Dupuy AJ. Abstract 1188: Cell-of-origin determines genetic selection and defines T-cell acute lymphocytic leukemia sub-types in mouse models Cancer Research. 70: 1188-1188. DOI: 10.1158/1538-7445.Am10-1188 |
0.45 |
|
| 2009 |
Collier LS, Adams DJ, Hackett CS, Bendzick LE, Akagi K, Davies MN, Diers MD, Rodriguez FJ, Bender AM, Tieu C, Matise I, Dupuy AJ, Copeland NG, Jenkins NA, Hodgson JG, et al. Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality. Cancer Research. 69: 8429-37. PMID 19843846 DOI: 10.1158/0008-5472.Can-09-1760 |
0.472 |
|
| 2009 |
Dupuy AJ, Rogers LM, Kim J, Nannapaneni K, Starr TK, Liu P, Largaespada DA, Scheetz TE, Jenkins NA, Copeland NG. A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice. Cancer Research. 69: 8150-6. PMID 19808965 DOI: 10.1158/0008-5472.Can-09-1135 |
0.677 |
|
| 2009 |
Starr TK, Allaei R, Silverstein KA, Staggs RA, Sarver AL, Bergemann TL, Gupta M, O'Sullivan MG, Matise I, Dupuy AJ, Collier LS, Powers S, Oberg AL, Asmann YW, Thibodeau SN, et al. A transposon-based genetic screen in mice identifies genes altered in colorectal cancer. Science (New York, N.Y.). 323: 1747-50. PMID 19251594 DOI: 10.1126/Science.1163040 |
0.46 |
|
| 2009 |
Keng VW, Villanueva A, Chiang DY, Dupuy AJ, Ryan BJ, Matise I, Silverstein KA, Sarver A, Starr TK, Akagi K, Tessarollo L, Collier LS, Powers S, Lowe SW, Jenkins NA, et al. A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma. Nature Biotechnology. 27: 264-74. PMID 19234449 DOI: 10.1038/Nbt.1526 |
0.486 |
|
| 2009 |
Starr TK, Allaei R, O'Sullivan MG, Sarver AL, Dupuy AJ, Jenkins NA, Copeland NG, Largaespada DA. Abstract A14: A forward genetic screen for genes that cooperate with PTEN in lung cancer development Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-A14 |
0.406 |
|
| 2008 |
Su Q, Prosser HM, Campos LS, Ortiz M, Nakamura T, Warren M, Dupuy AJ, Jenkins NA, Copeland NG, Bradley A, Liu P. A DNA transposon-based approach to validate oncogenic mutations in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 105: 19904-9. PMID 19064922 DOI: 10.1073/Pnas.0807785105 |
0.451 |
|
| 2006 |
Dupuy AJ, Jenkins NA, Copeland NG. Sleeping beauty: a novel cancer gene discovery tool. Human Molecular Genetics. 15: R75-9. PMID 16651372 DOI: 10.1093/Hmg/Ddl061 |
0.456 |
|
| 2005 |
Collier LS, Carlson CM, Ravimohan S, Dupuy AJ, Largaespada DA. Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse. Nature. 436: 272-6. PMID 16015333 DOI: 10.1038/Nature03681 |
0.476 |
|
| 2005 |
Dupuy AJ, Akagi K, Largaespada DA, Copeland NG, Jenkins NA. Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system. Nature. 436: 221-6. PMID 16015321 DOI: 10.1038/Nature03691 |
0.46 |
|
| 2004 |
Dave UP, Akagi K, Dupuy A, Suzuki T, Jenkins NA, Copeland NG. Proviral Tagging Combined with Human Microarray Data Reveals Genes and Pathways That Cooperate in Disease Induction. Blood. 104: 3492-3492. DOI: 10.1182/Blood.V104.11.3492.3492 |
0.471 |
|
| 2003 |
Belur LR, Frandsen JL, Dupuy AJ, Ingbar DH, Largaespada DA, Hackett PB, Scott McIvor R. Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 501-7. PMID 12946324 DOI: 10.1016/S1525-0016(03)00211-9 |
0.33 |
|
| 2003 |
Geurts AM, Yang Y, Clark KJ, Liu G, Cui Z, Dupuy AJ, Bell JB, Largaespada DA, Hackett PB. Gene transfer into genomes of human cells by the sleeping beauty transposon system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 108-17. PMID 12842434 DOI: 10.1016/S1525-0016(03)00099-6 |
0.372 |
|
| 2002 |
Dupuy AJ, Clark K, Carlson CM, Fritz S, Davidson AE, Markley KM, Finley K, Fletcher CF, Ekker SC, Hackett PB, Horn S, Largaespada DA. Mammalian germ-line transgenesis by transposition. Proceedings of the National Academy of Sciences of the United States of America. 99: 4495-9. PMID 11904379 DOI: 10.1073/Pnas.062630599 |
0.349 |
|
| 2001 |
Dupuy AJ, Fritz S, Largaespada DA. Transposition and gene disruption in the male germline of the mouse Genesis. 30: 82-88. PMID 11416868 DOI: 10.1002/Gene.1037 |
0.404 |
|
| 2001 |
Dupuy AJ, Morgan K, Von Lintig FC, Shen H, Acar H, Hasz DE, Jenkins NA, Copeland NG, Boss GR, Largaespada DA. Activation of the Rap1 Guanine Nucleotide Exchange Gene, CalDAG-GEF I, in BXH-2 Murine Myeloid Leukemia Journal of Biological Chemistry. 276: 11804-11811. PMID 11278453 DOI: 10.1074/Jbc.M008970200 |
0.301 |
|
| 1999 |
Li J, Shen H, Himmel KL, Dupuy AJ, Largaespada DA, Nakamura T, Shaughnessy JD, Jenkins NA, Copeland NG. Leukaemia disease genes: large-scale cloning and pathway predictions. Nature Genetics. 23: 348-53. PMID 10610183 DOI: 10.1038/15531 |
0.374 |
|
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