Holly M. Brothers - Publications

Affiliations: 
Ohio State University, Columbus, Columbus, OH 
Area:
Alzheimer's disease

18/45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Hopp SC, Royer S, Brothers HM, Kaercher RM, D'Angelo H, Bardou I, Wenk GL. Age-associated alterations in the time-dependent profile of pro- and anti-inflammatory proteins within the hippocampus in response to acute exposure to interleukin-1β. Journal of Neuroimmunology. 267: 86-91. PMID 24393520 DOI: 10.1016/J.Jneuroim.2013.12.010  0.801
2014 Bardou I, Kaercher RM, Brothers HM, Hopp SC, Royer S, Wenk GL. Age and duration of inflammatory environment differentially affect the neuroimmune response and catecholaminergic neurons in the midbrain and brainstem. Neurobiology of Aging. 35: 1065-73. PMID 24315728 DOI: 10.1016/J.Neurobiolaging.2013.11.006  0.795
2013 Brothers HM, Bardou I, Hopp SC, Marchalant Y, Kaercher RM, Turner SM, Mitchem MR, Kigerl K, Wenk GL. Time-Dependent Compensatory Responses to Chronic Neuroinflammation in Hippocampus and Brainstem: The Potential Role of Glutamate Neurotransmission. Journal of Alzheimer's Disease & Parkinsonism. 3: 110. PMID 24600537 DOI: 10.4172/2161-0460.1000110  0.766
2013 Brothers HM, Bardou I, Hopp SC, Kaercher RM, Corona AW, Fenn AM, Godbout JP, Wenk GL. Riluzole partially rescues age-associated, but not LPS-induced, loss of glutamate transporters and spatial memory. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 1098-105. PMID 23709339 DOI: 10.1007/S11481-013-9476-2  0.825
2013 Bardou I, Brothers HM, Kaercher RM, Hopp SC, Wenk GL. Differential effects of duration and age on the consequences of neuroinflammation in the hippocampus. Neurobiology of Aging. 34: 2293-301. PMID 23639208 DOI: 10.1016/J.Neurobiolaging.2013.03.034  0.817
2012 Cerbai F, Lana D, Nosi D, Petkova-Kirova P, Zecchi S, Brothers HM, Wenk GL, Giovannini MG. The neuron-astrocyte-microglia triad in normal brain ageing and in a model of neuroinflammation in the rat hippocampus. Plos One. 7: e45250. PMID 23028880 DOI: 10.1371/Journal.Pone.0045250  0.826
2011 Norman GJ, Morris JS, Karelina K, Weil ZM, Zhang N, Al-Abed Y, Brothers HM, Wenk GL, Pavlov VA, Tracey KJ, Devries AC. Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3446-52. PMID 21368056 DOI: 10.1523/JNEUROSCI.4558-10.2011  0.673
2011 Brothers H, Hopp S, Bardou I, Wenk G. P3-422: Elevated glutamate transport by GLT1 attenuates inflammation-induced memory impairment Alzheimer's & Dementia. 7: S650-S650. DOI: 10.1016/J.Jalz.2011.05.1865  0.764
2011 Bardou I, Brothers H, Marchalant Y, Wenk G. P3-417: Stimulation of endocannabinoid receptors is required for reduction of neuroinflammation and restoration of neurogenesis in the aged brain Alzheimer's & Dementia. 7: S649-S649. DOI: 10.1016/j.jalz.2011.05.1860  0.521
2010 Brothers HM, Marchalant Y, Wenk GL. Caffeine attenuates lipopolysaccharide-induced neuroinflammation. Neuroscience Letters. 480: 97-100. PMID 20541589 DOI: 10.1016/j.neulet.2010.06.013  0.81
2009 Marchalant Y, Brothers HM, Wenk GL. Cannabinoid agonist WIN-55,212-2 partially restores neurogenesis in the aged rat brain. Molecular Psychiatry. 14: 1068-9. PMID 19920834 DOI: 10.1038/mp.2009.62  0.813
2009 Marchalant Y, Brothers HM, Wenk GL. New neuron production can be increased in the hippocampus of aged rats following cannabinoid treatment. Molecular Psychiatry. 14: 1067, 1068-9. PMID 19920833 DOI: 10.1038/mp.2009.122  0.791
2009 Marchalant Y, Brothers HM, Norman GJ, Karelina K, DeVries AC, Wenk GL. Cannabinoids attenuate the effects of aging upon neuroinflammation and neurogenesis. Neurobiology of Disease. 34: 300-7. PMID 19385063 DOI: 10.1016/J.Nbd.2009.01.014  0.811
2008 Knox D, Brothers H, Norman GJ, Berntson GG. Nucleus basalis magnocellularis and substantia innominata corticopetal cholinergic lesions attenuate freezing induced by predator odor. Behavioral Neuroscience. 122: 601-10. PMID 18513130 DOI: 10.1037/0735-7044.122.3.601  0.47
2008 Marchalant Y, Brothers HM, Wenk GL. Inflammation and aging: can endocannabinoids help? Biomedicine & Pharmacotherapy = Biomã©Decine & Pharmacothã©Rapie. 62: 212-7. PMID 18400455 DOI: 10.1016/j.biopha.2008.02.004  0.765
2008 Marchalant Y, Cerbai F, Brothers HM, Wenk GL. Cannabinoid receptor stimulation is anti-inflammatory and improves memory in old rats. Neurobiology of Aging. 29: 1894-901. PMID 17561311 DOI: 10.1016/J.Neurobiolaging.2007.04.028  0.785
2008 Brothers H, Cerbai F, Marchalant Y, Wenk G. P3-353: Regional susceptibility to inflammation: Neuron-glia interactions in the hippocampus and substantia nigra and rescue by the NMDA antagonist memantine Alzheimer's & Dementia. 4: T625-T625. DOI: 10.1016/J.Jalz.2008.05.1923  0.731
2008 Marchalant Y, Brothers HM, Wenk GL. P2-398: Role Of endocannabinoids on neuroinflammation, memory and neurogenesis in aged rats Alzheimer's & Dementia. 4: T489-T490. DOI: 10.1016/j.jalz.2008.05.1476  0.796
Low-probability matches (unlikely to be authored by this person)
2016 Haim A, Julian D, Albin-Brooks C, Brothers HM, Lenz KM, Leuner B. A survey of neuroimmune changes in pregnant and postpartum female rats. Brain, Behavior, and Immunity. PMID 27686844 DOI: 10.1016/J.Bbi.2016.09.026  0.237
2015 Latta CH, Sudduth TL, Weekman EM, Brothers HM, Abner EL, Popa GJ, Mendenhall MD, Gonzalez-Oregon F, Braun K, Wilcock DM. Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-β using BV2 microglial cells and APP/PS1 transgenic mice. Journal of Neuroinflammation. 12: 41. PMID 25885682 DOI: 10.1186/S12974-015-0243-6  0.203
2013 Brothers HM, Wilcock DM. Are inflammatory profiles the key to personalized Alzheimer's treatment? Neurodegenerative Disease Management. 3: 343-351. PMID 25614767 DOI: 10.2217/nmt.13.40  0.197
2014 Latta CH, Brothers HM, Wilcock DM. Neuroinflammation in Alzheimer's disease; A source of heterogeneity and target for personalized therapy. Neuroscience. PMID 25286385 DOI: 10.1016/j.neuroscience.2014.09.061  0.185
2014 Weekman EM, Sudduth TL, Abner EL, Popa GJ, Mendenhall MD, Brothers HM, Braun K, Greenstein A, Wilcock DM. Transition from an M1 to a mixed neuroinflammatory phenotype increases amyloid deposition in APP/PS1 transgenic mice. Journal of Neuroinflammation. 11: 127. PMID 25062954 DOI: 10.1186/1742-2094-11-127  0.182
2018 Brothers HM, Gosztyla ML, Robinson SR. The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease. Frontiers in Aging Neuroscience. 10: 118. PMID 29922148 DOI: 10.3389/Fnagi.2018.00118  0.176
2014 Sudduth TL, Weekman EM, Brothers HM, Braun K, Wilcock DM. β-amyloid deposition is shifted to the vasculature and memory impairment is exacerbated when hyperhomocysteinemia is induced in APP/PS1 transgenic mice. Alzheimer's Research & Therapy. 6: 32. PMID 24991237 DOI: 10.1186/alzrt262  0.119
2018 Robinson SR, Brothers HM, Gosztyla ML. Consequences of redefining Alzheimer's disease in terms of amyloid burden without regard to cognitive decline. Neural Regeneration Research. 13: 2098-2099. PMID 30323134 DOI: 10.4103/1673-5374.241456  0.114
2016 Penninkilampi R, Brothers HM, Eslick GD. Safety and Efficacy of Anti-Amyloid-β Immunotherapy in Alzheimer's Disease: A Systematic Review and Meta-Analysis. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 28025724 DOI: 10.1007/s11481-016-9722-5  0.099
2018 Gosztyla ML, Brothers HM, Robinson SR. Alzheimer's Amyloid-β is an Antimicrobial Peptide: A Review of the Evidence. Journal of Alzheimer's Disease : Jad. PMID 29504537 DOI: 10.3233/Jad-171133  0.099
2016 Penninkilampi R, Brothers HM, Eslick GD. Pharmacological Agents Targeting γ-Secretase Increase Risk of Cancer and Cognitive Decline in Alzheimer's Disease Patients: A Systematic Review and Meta-Analysis. Journal of Alzheimer's Disease : Jad. PMID 27392862 DOI: 10.3233/JAD-160275  0.096
2016 Penninkilampi R, Brothers HM, Eslick GD. P1-043: Immunotherapy Targeting Amyloid-Beta in Alzheimer's Disease: A Meta-Analysis Alzheimer's & Dementia. 12: P418-P418. DOI: 10.1016/j.jalz.2016.06.790  0.077
2016 Penninkilampi R, Brothers HM, Eslick GD. P2-004: Drugs Targeting Gamma-Secretase Are Associated with Cognitive Decline and Elevated Risk of Skin Cancer: A Meta-Analysis Alzheimer's & Dementia. 12: P609-P609. DOI: 10.1016/j.jalz.2016.06.1208  0.069
1999 Tömalia PA, Uppulurit S, Swanson DR, Brothers HM, Pieler LT, Lit J, Meier DJ, Hagnauer GL, Balogh L. Dendritic macromolecules: a fourth major class of polymer architecture - new properties driven by architecture Materials Research Society Symposium - Proceedings. 543: 289-298.  0.04
1992 Zhou JS, Brothers HM, Neddersen JP, Peerey LM, Cotton TM, Kostić NM. Metalloprotein complexes for the study of electron-transfer reactions. Characterization of diprotein complexes obtained by covalent cross-linking of cytochrome c and plastocyanin with a carbodiimide. Bioconjugate Chemistry. 3: 382-90. PMID 1329988  0.038
1988 Brothers HM, Kostić NM. Noninvasive tagging of proteins with an inorganic chromophore. Selectivity of chloro(terpyridine)platinum(II) toward amino acids, peptides, and cytochromes c Inorganic Chemistry. 27: 1761-1767.  0.032
1991 Peerey LM, Brothers HM, Hazzard JT, Tollin G, Kostić NM. Unimolecular and bimolecular oxidoreduction reactions involving diprotein complexes of cytochrome c and plastocyanin. Dependence of electron-transfer reactivity on charge and orientation of the docked metalloproteins. Biochemistry. 30: 9297-304. PMID 1654092 DOI: 10.1021/bi00102a023  0.03
1994 Wiener EC, Brechbiel MW, Brothers H, Magin RL, Gansow OA, Tomalia DA, Lauterbur PC. Dendrimer-based metal chelates: a new class of magnetic resonance imaging contrast agents. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 31: 1-8. PMID 8121264 DOI: 10.1002/Mrm.1910310102  0.03
2002 Tomalia DA, Brothers HM, Piehler LT, Durst HD, Swanson DR. Partial shell-filled core-shell tecto(dendrimers): a strategy to surface differentiated nano-clefts and cusps. Proceedings of the National Academy of Sciences of the United States of America. 99: 5081-7. PMID 11943851 DOI: 10.1073/pnas.062684999  0.025
1993 Brothers HM, Zhou JS, Kostić NM. Protein-protein orientation in electron-transfer reactions of the cytochrome c/plastocyanin complex with free cytochrome c and with free plastocyanin Journal of Inorganic and Organometallic Polymers. 3: 59-76. DOI: 10.1007/BF00696753  0.017
1987 Ratilla EMA, Brothers HM, Kostić NM. A transition-metal chromophore as a new, sensitive spectroscopic tag for proteins. Selective covalent labeling of histidine residues in cytochromes c with chloro(2,2′:6′,2″-terpyridine)platinum(II) chloride Journal of the American Chemical Society. 109: 4592-4599.  0.014
1999 Li J, Swanson DR, Qin D, Brothers HM, Piehler LT, Tomalia D, Meier DJ. Characterizations of core-shell tecto-(dendrimer) molecules by tapping mode atomic force microscopy Langmuir. 15: 7347-7350.  0.013
1999 Li J, Swanson DR, Qin D, Brothers HM, Piehler LT, Meier DJ, Tomalia DA. The characterization of core-shell tecto(dendrimer) molecules by tapping mode atomic force microscopy American Chemical Society, Polymer Preprints, Division of Polymer Chemistry. 40: 723-724.  0.013
2003 Tomalia DA, Huang B, Swanson DR, Brothers HM, Klimash JW. Structure control within poly(amidoamine) dendrimers: Size, shape and regio-chemical mimicry of globular proteins Tetrahedron. 59: 3799-3813. DOI: 10.1016/S0040-4020(03)00430-7  0.011
1998 Brothers HM, Piehler LT, Tomalia DA. Slab-gel and capillary electrophoretic characterization of polyamidoamine dendrimers Journal of Chromatography A. 814: 233-246. DOI: 10.1016/S0021-9673(98)00419-1  0.01
1997 Tolić LP, Anderson GA, Smith RD, Brothers HM, Spindler R, Tomalia DA. Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometric characterization of high molecular mass Starburst™ dendrimers International Journal of Mass Spectrometry and Ion Processes. 165: 405-418.  0.01
1990 Brothers HM, Kostić NM. Catalytic activity of the serine proteases alpha-chymotrypsin and alpha-lytic protease tagged at the active site with a (terpyridine)platinum(II) chromophore. Biochemistry. 29: 7468-74. PMID 2223778  0.01
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