David A. Calderwood - Publications

Affiliations: 
Cell Biology Yale University, New Haven, CT 
Area:
Cell Biology, Molecular Biology, Biochemistry

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Huet-Calderwood C, Rivera-Molina F, Toomre D, Calderwood DA. Use of Ecto-Tagged Integrins to Monitor Integrin Exocytosis and Endocytosis. Methods in Molecular Biology (Clifton, N.J.). 2608: 17-38. PMID 36653699 DOI: 10.1007/978-1-0716-2887-4_2  0.3
2022 Huet-Calderwood C, Rivera-Molina FE, Toomre DK, Calderwood DA. Fibroblasts secrete fibronectin under lamellipodia in a microtubule- and myosin II-dependent fashion. The Journal of Cell Biology. 222. PMID 36416725 DOI: 10.1083/jcb.202204100  0.452
2022 Ha BH, Yigit S, Natarajan N, Morse EM, Calderwood DA, Boggon TJ. Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4). Communications Biology. 5: 1257. PMID 36385162 DOI: 10.1038/s42003-022-04157-3  0.351
2022 Kanchanawong P, Calderwood DA. Organization, dynamics and mechanoregulation of integrin-mediated cell-ECM adhesions. Nature Reviews. Molecular Cell Biology. PMID 36168065 DOI: 10.1038/s41580-022-00531-5  0.392
2021 Solano-Collado V, Colamarino RA, Calderwood DA, Baldassarre M, Spanò S. A Small-Scale shRNA Screen in Primary Mouse Macrophages Identifies a Role for the Rab GTPase Rab1b in Controlling Typhi Growth. Frontiers in Cellular and Infection Microbiology. 11: 660689. PMID 33898333 DOI: 10.3389/fcimb.2021.660689  0.669
2020 Su VL, Calderwood DA. Signalling through cerebral cavernous malformation protein networks. Open Biology. 10: 200263. PMID 33234067 DOI: 10.1098/rsob.200263  0.321
2020 Kadry YA, Maisuria EM, Huet-Calderwood C, Calderwood DA. Differences in self-association between kindlin-2 and kindlin-3 are associated with differential integrin binding. The Journal of Biological Chemistry. PMID 32546480 DOI: 10.1074/Jbc.Ra120.013618  0.477
2020 Su VL, Simon B, Draheim KM, Calderwood DA. Serine phosphorylation of the small phosphoprotein ICAP1 inhibits its nuclear accumulation. The Journal of Biological Chemistry. PMID 32005669 DOI: 10.1074/Jbc.Ra119.009794  0.453
2020 Kadry YA, Calderwood DA. Chapter 22: Structural and signaling functions of integrins. Biochimica Et Biophysica Acta. Biomembranes. 183206. PMID 31991120 DOI: 10.1016/J.Bbamem.2020.183206  0.499
2019 Sun X, Su VL, Calderwood DA. The subcellular localization of type I p21-activated kinases is controlled by the disordered variable region and polybasic sequences. The Journal of Biological Chemistry. PMID 31391252 DOI: 10.1074/Jbc.Ra119.007692  0.481
2019 Kumar A, Shutova MS, Tanaka K, Iwamoto DV, Calderwood DA, Svitkina TM, Schwartz MA. Filamin A mediates isotropic distribution of applied force across the actin network. The Journal of Cell Biology. PMID 31315944 DOI: 10.1083/Jcb.201901086  0.375
2019 Bidone TC, Polley A, Jin J, Driscoll T, Iwamoto DV, Calderwood DA, Schwartz MA, Voth GA. Coarse-Grained Simulation of Full-Length Integrin Activation. Biophysical Journal. PMID 30851876 DOI: 10.1016/J.Bpj.2019.02.011  0.38
2018 Kadry YA, Huet-Calderwood C, Simon B, Calderwood DA. Kindlin-2 interacts with a highly-conserved surface of ILK to regulate focal adhesion localization and cell spreading. Journal of Cell Science. PMID 30254023 DOI: 10.1242/Jcs.221184  0.594
2018 Iwamoto DV, Huehn A, Simon B, Huet-Calderwood C, Baldassarre M, Sindelar CV, Calderwood DA. Structural basis of the filamin A actin-binding domain interaction with F-actin. Nature Structural & Molecular Biology. PMID 30224736 DOI: 10.1038/S41594-018-0128-3  0.769
2018 Calderwood D. Cell adhesion and the cytoskeleton Cryobiology. 81: 221. DOI: 10.1016/j.cryobiol.2017.12.041  0.364
2017 Huet-Calderwood C, Rivera-Molina F, Iwamoto DV, Kromann EB, Toomre D, Calderwood DA. Novel ecto-tagged integrins reveal their trafficking in live cells. Nature Communications. 8: 570. PMID 28924207 DOI: 10.1038/S41467-017-00646-W  0.491
2016 Draheim KM, Huet-Calderwood C, Simon B, Calderwood DA. Nuclear Localization of Integrin Cytoplasmic Associated Protein-1 Influences β1 Integrin Activation and Recruits Krev/ Interaction Trapped-1 to the Nucleus. The Journal of Biological Chemistry. PMID 28003363 DOI: 10.1074/Jbc.M116.762393  0.474
2016 Shi X, Mihaylova VT, Kuruvilla L, Chen F, Viviano S, Baldassarre M, Sperandio D, Martinez R, Yue P, Bates JG, Breckenridge DG, Schlessinger J, Turk BE, Calderwood DA. Loss of TRIM33 causes resistance to BET bromodomain inhibitors through MYC- and TGF-β-dependent mechanisms. Proceedings of the National Academy of Sciences of the United States of America. PMID 27432991 DOI: 10.1073/Pnas.1608319113  0.731
2015 Calderwood DA. The Rap1-RIAM pathway prefers β2 integrins. Blood. 126: 2658-9. PMID 26679542 DOI: 10.1182/Blood-2015-09-668962  0.363
2015 Morse EM, Sun X, Olberding JR, Ha BH, Boggon TJ, Calderwood DA. PAK6 targets to cell-cell adhesions via its N-terminus in a Cdc42-dependent manner to drive epithelial colony escape. Journal of Cell Science. PMID 26598554 DOI: 10.1242/Jcs.177493  0.503
2015 Iwamoto DV, Calderwood DA. Regulation of integrin-mediated adhesions. Current Opinion in Cell Biology. 36: 41-7. PMID 26189062 DOI: 10.1016/J.Ceb.2015.06.009  0.573
2015 Draheim KM, Li X, Zhang R, Fisher OS, Villari G, Boggon TJ, Calderwood DA. CCM2-CCM3 interaction stabilizes their protein expression and permits endothelial network formation. The Journal of Cell Biology. 208: 987-1001. PMID 25825518 DOI: 10.1083/Jcb.201407129  0.474
2015 Simpson MA, Bradley WD, Harburger D, Parsons M, Calderwood DA, Koleske AJ. Direct interactions with the integrin β1 cytoplasmic tail activate the Abl2/Arg kinase. The Journal of Biological Chemistry. 290: 8360-72. PMID 25694433 DOI: 10.1074/Jbc.M115.638874  0.803
2015 Bancroft T, Bouaouina M, Roberts S, Lee M, Calderwood DA, Schwartz M, Simons M, Sessa WC, Kyriakides TR. Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function. The Journal of Biological Chemistry. 290: 409-22. PMID 25389299 DOI: 10.1074/Jbc.M114.618421  0.363
2014 Ellis SJ, Lostchuck E, Goult BT, Bouaouina M, Fairchild MJ, López-Ceballos P, Calderwood DA, Tanentzapf G. The talin head domain reinforces integrin-mediated adhesion by promoting adhesion complex stability and clustering. Plos Genetics. 10: e1004756. PMID 25393120 DOI: 10.1371/Journal.Pgen.1004756  0.526
2014 Huet-Calderwood C, Brahme NN, Kumar N, Stiegler AL, Raghavan S, Boggon TJ, Calderwood DA. Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation. Journal of Cell Science. 127: 4308-21. PMID 25086068 DOI: 10.1242/Jcs.155879  0.551
2014 Uchil PD, Pawliczek T, Reynolds TD, Ding S, Hinz A, Munro JB, Huang F, Floyd RW, Yang H, Hamilton WL, Bewersdorf J, Xiong Y, Calderwood DA, Mothes W. TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly. Journal of Cell Science. 127: 3928-42. PMID 25015296 DOI: 10.1242/Dev.117242  0.534
2014 Lee MY, Skoura A, Park EJ, Landskroner-Eiger S, Jozsef L, Luciano AK, Murata T, Pasula S, Dong Y, Bouaouina M, Calderwood DA, Ferguson SM, De Camilli P, Sessa WC. Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis. Development (Cambridge, England). 141: 1465-72. PMID 24598168 DOI: 10.1242/Jcs.153080  0.391
2014 Tian X, Kim JJ, Monkley SM, Gotoh N, Nandez R, Soda K, Inoue K, Balkin DM, Hassan H, Son SH, Lee Y, Moeckel G, Calderwood DA, Holzman LB, Critchley DR, et al. Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance. The Journal of Clinical Investigation. 124: 1098-113. PMID 24531545 DOI: 10.1172/Jci69778  0.421
2014 Draheim KM, Fisher OS, Boggon TJ, Calderwood DA. Cerebral cavernous malformation proteins at a glance. Journal of Cell Science. 127: 701-7. PMID 24481819 DOI: 10.1242/Jcs.138388  0.429
2014 Morse EM, Brahme NN, Calderwood DA. Integrin cytoplasmic tail interactions. Biochemistry. 53: 810-20. PMID 24467163 DOI: 10.1021/Bi401596Q  0.607
2013 Gao J, Ha BH, Lou HJ, Morse EM, Zhang R, Calderwood DA, Turk BE, Boggon TJ. Substrate and inhibitor specificity of the type II p21-activated kinase, PAK6. Plos One. 8: e77818. PMID 24204982 DOI: 10.1371/Journal.Pone.0077818  0.337
2013 Brahme NN, Harburger DS, Kemp-O'Brien K, Stewart R, Raghavan S, Parsons M, Calderwood DA. Kindlin binds migfilin tandem LIM domains and regulates migfilin focal adhesion localization and recruitment dynamics. The Journal of Biological Chemistry. 288: 35604-16. PMID 24165133 DOI: 10.1074/Jbc.M113.483016  0.841
2013 Razinia Z, Baldassarre M, Cantelli G, Calderwood DA. ASB2α, an E3 ubiquitin ligase specificity subunit, regulates cell spreading and triggers proteasomal degradation of filamins by targeting the filamin calponin homology 1 domain. The Journal of Biological Chemistry. 288: 32093-105. PMID 24052262 DOI: 10.1074/Jbc.M113.496604  0.822
2013 Calderwood DA, Campbell ID, Critchley DR. Talins and kindlins: Partners in integrin-mediated adhesion Nature Reviews Molecular Cell Biology. 14: 503-517. PMID 23860236 DOI: 10.1038/Nrm3624  0.605
2013 Stiegler AL, Grant TD, Luft JR, Calderwood DA, Snell EH, Boggon TJ. Purification and SAXS analysis of the integrin linked kinase, PINCH, parvin (IPP) heterotrimeric complex. Plos One. 8: e55591. PMID 23383235 DOI: 10.1371/Journal.Pone.0055591  0.43
2013 Liu W, Draheim KM, Zhang R, Calderwood DA, Boggon TJ. Mechanism for KRIT1 release of ICAP1-mediated suppression of integrin activation. Molecular Cell. 49: 719-29. PMID 23317506 DOI: 10.1016/J.Molcel.2012.12.005  0.509
2012 Yates LA, Lumb CN, Brahme NN, Zalyte R, Bird LE, De Colibus L, Owens RJ, Calderwood DA, Sansom MS, Gilbert RJ. Structural and functional characterization of the kindlin-1 pleckstrin homology domain. The Journal of Biological Chemistry. 287: 43246-61. PMID 23132860 DOI: 10.1074/Jbc.M112.422089  0.436
2012 Bouaouina M, Jani K, Long JY, Czerniecki S, Morse EM, Ellis SJ, Tanentzapf G, Schöck F, Calderwood DA. Zasp regulates integrin activation. Journal of Cell Science. 125: 5647-57. PMID 22992465 DOI: 10.1242/Jcs.103291  0.553
2012 Brahme NN, Calderwood DA. Cell adhesion: a FERM grasp of the tail sorts out integrins. Current Biology : Cb. 22: R692-4. PMID 22974999 DOI: 10.1016/J.Cub.2012.07.049  0.598
2012 Coyer SR, Singh A, Dumbauld DW, Calderwood DA, Craig SW, Delamarche E, García AJ. Nanopatterning reveals an ECM area threshold for focal adhesion assembly and force transmission that is regulated by integrin activation and cytoskeleton tension. Journal of Cell Science. 125: 5110-23. PMID 22899715 DOI: 10.1242/Jcs.108035  0.408
2012 Stiegler AL, Draheim KM, Li X, Chayen NE, Calderwood DA, Boggon TJ. Structural basis for paxillin binding and focal adhesion targeting of β-parvin. The Journal of Biological Chemistry. 287: 32566-77. PMID 22869380 DOI: 10.1074/Jbc.M112.367342  0.525
2012 Baldassarre M, Razinia Z, Brahme NN, Buccione R, Calderwood DA. Filamin A controls matrix metalloproteinase activity and regulates cell invasion in human fibrosarcoma cells. Journal of Cell Science. 125: 3858-69. PMID 22595522 DOI: 10.1242/Jcs.104018  0.804
2012 Li X, Zhang R, Draheim KM, Liu W, Calderwood DA, Boggon TJ. Structural basis for small G protein effector interaction of Ras-related protein 1 (Rap1) and adaptor protein Krev interaction trapped 1 (KRIT1). The Journal of Biological Chemistry. 287: 22317-27. PMID 22577140 DOI: 10.1074/Jbc.M112.361295  0.464
2012 Razinia Z, Mäkelä T, Ylänne J, Calderwood DA. Filamins in mechanosensing and signaling. Annual Review of Biophysics. 41: 227-46. PMID 22404683 DOI: 10.1146/Annurev-Biophys-050511-102252  0.831
2012 Guiet R, Vérollet C, Lamsoul I, Cougoule C, Poincloux R, Labrousse A, Calderwood DA, Glogauer M, Lutz PG, Maridonneau-Parini I. Macrophage mesenchymal migration requires podosome stabilization by filamin A. The Journal of Biological Chemistry. 287: 13051-62. PMID 22334688 DOI: 10.1074/Jbc.M111.307124  0.457
2012 Bandyopadhyay A, Rothschild G, Kim S, Calderwood DA, Raghavan S. Functional differences between kindlin-1 and kindlin-2 in keratinocytes. Journal of Cell Science. 125: 2172-84. PMID 22328497 DOI: 10.1242/Jcs.096214  0.555
2012 Lawson C, Lim ST, Uryu S, Chen XL, Calderwood DA, Schlaepfer DD. FAK promotes recruitment of talin to nascent adhesions to control cell motility. The Journal of Cell Biology. 196: 223-32. PMID 22270917 DOI: 10.1083/Jcb.201108078  0.583
2012 Bouaouina M, Goult BT, Huet-Calderwood C, Bate N, Brahme NN, Barsukov IL, Critchley DR, Calderwood DA. A conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbβ3 integrin coactivation. The Journal of Biological Chemistry. 287: 6979-90. PMID 22235127 DOI: 10.1074/Jbc.M111.330845  0.568
2012 Bouaouina M, Harburger DS, Calderwood DA. Talin and signaling through integrins. Methods in Molecular Biology (Clifton, N.J.). 757: 325-47. PMID 21909921 DOI: 10.1007/978-1-61779-166-6_20  0.845
2011 Razinia Z, Baldassarre M, Bouaouina M, Lamsoul I, Lutz PG, Calderwood DA. The E3 ubiquitin ligase specificity subunit ASB2α targets filamins for proteasomal degradation by interacting with the filamin actin-binding domain. Journal of Cell Science. 124: 2631-41. PMID 21750192 DOI: 10.1242/Jcs.084343  0.832
2011 Lamsoul I, Burande CF, Razinia Z, Houles TC, Menoret D, Baldassarre M, Erard M, Moog-Lutz C, Calderwood DA, Lutz PG. Functional and structural insights into ASB2alpha, a novel regulator of integrin-dependent adhesion of hematopoietic cells. The Journal of Biological Chemistry. 286: 30571-81. PMID 21737450 DOI: 10.1074/Jbc.M111.220921  0.805
2010 Goult BT, Bouaouina M, Elliott PR, Bate N, Patel B, Gingras AR, Grossmann JG, Roberts GC, Calderwood DA, Critchley DR, Barsukov IL. Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation. The Embo Journal. 29: 1069-80. PMID 20150896 DOI: 10.1038/Emboj.2010.4  0.388
2010 Chiswell BP, Stiegler AL, Razinia Z, Nalibotski E, Boggon TJ, Calderwood DA. Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase. Journal of Structural Biology. 170: 157-63. PMID 19963065 DOI: 10.1016/J.Jsb.2009.12.002  0.828
2009 Baldassarre M, Razinia Z, Burande CF, Lamsoul I, Lutz PG, Calderwood DA. Filamins regulate cell spreading and initiation of cell migration. Plos One. 4: e7830. PMID 19915675 DOI: 10.1371/Journal.Pone.0007830  0.814
2009 Goult BT, Bouaouina M, Harburger DS, Bate N, Patel B, Anthis NJ, Campbell ID, Calderwood DA, Barsukov IL, Roberts GC, Critchley DR. The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation. Journal of Molecular Biology. 394: 944-56. PMID 19804783 DOI: 10.1016/J.Jmb.2009.09.061  0.787
2009 Gehler S, Baldassarre M, Lad Y, Leight JL, Wozniak MA, Riching KM, Eliceiri KW, Weaver VM, Calderwood DA, Keely PJ. Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension. Molecular Biology of the Cell. 20: 3224-38. PMID 19458194 DOI: 10.1091/Mbc.E08-12-1186  0.751
2009 Bello NF, Lamsoul I, Heuzé ML, Métais A, Moreaux G, Calderwood DA, Duprez D, Moog-Lutz C, Lutz PG. The E3 ubiquitin ligase specificity subunit ASB2β is a novel regulator of muscle differentiation that targets filamin B to proteasomal degradation Cell Death and Differentiation. 16: 921-932. PMID 19300455 DOI: 10.1038/Cdd.2009.27  0.426
2009 Harburger DS, Bouaouina M, Calderwood DA. Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects. The Journal of Biological Chemistry. 284: 11485-97. PMID 19240021 DOI: 10.1074/Jbc.M809233200  0.818
2009 Shifrin Y, Arora PD, Ohta Y, Calderwood DA, McCulloch CA. The role of FilGAP-filamin A interactions in mechanoprotection. Molecular Biology of the Cell. 20: 1269-79. PMID 19144823 DOI: 10.1091/Mbc.E08-08-0872  0.446
2009 Harburger DS, Calderwood DA. Integrin signalling at a glance. Journal of Cell Science. 122: 159-63. PMID 19118207 DOI: 10.1242/Jcs.018093  0.802
2008 Chiswell BP, Zhang R, Murphy JW, Boggon TJ, Calderwood DA. The structural basis of integrin-linked kinase-PINCH interactions. Proceedings of the National Academy of Sciences of the United States of America. 105: 20677-82. PMID 19074270 DOI: 10.1073/Pnas.0811415106  0.503
2008 Luissint AC, Lutz PG, Calderwood DA, Couraud PO, Bourdoulous S. JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation. The Journal of Cell Biology. 183: 1159-73. PMID 19064666 DOI: 10.1083/Jcb.200805061  0.38
2008 Lad Y, Jiang P, Ruskamo S, Harburger DS, Ylänne J, Campbell ID, Calderwood DA. Structural basis of the migfilin-filamin interaction and competition with integrin β tails Journal of Biological Chemistry. 283: 35154-35163. PMID 18829455 DOI: 10.1074/Jbc.M802592200  0.839
2008 Heuzé ML, Lamsoul I, Baldassarre M, Lad Y, Lévêque S, Razinia Z, Moog-Lutz C, Calderwood DA, Lutz PG. ASB2 targets filamins A and B to proteasomal degradation. Blood. 112: 5130-40. PMID 18799729 DOI: 10.1182/Blood-2007-12-128744  0.796
2008 Bouaouina M, Lad Y, Calderwood DA. The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins. The Journal of Biological Chemistry. 283: 6118-25. PMID 18165225 DOI: 10.1074/Jbc.M709527200  0.427
2008 Luissint A, Lutz PG, Calderwood DA, Couraud P, Bourdoulous S. JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by α4β1 integrin activation The Journal of General Physiology. 133: i1-i1. DOI: 10.1085/Jgp1331Oia1  0.363
2007 Lad Y, Harburger DS, Calderwood DA. Integrin cytoskeletal interactions. Methods in Enzymology. 426: 69-84. PMID 17697880 DOI: 10.1016/S0076-6879(07)26004-5  0.834
2007 Lad Y, Kiema T, Jiang P, Pentikäinen OT, Coles CH, Campbell ID, Calderwood DA, Ylänne J. Structure of three tandem filamin domains reveals auto-inhibition of ligand binding. The Embo Journal. 26: 3993-4004. PMID 17690686 DOI: 10.1038/Sj.Emboj.7601827  0.532
2007 Evans EA, Calderwood DA. Forces and bond dynamics in cell adhesion. Science (New York, N.Y.). 316: 1148-53. PMID 17525329 DOI: 10.1126/Science.1137592  0.43
2006 Han J, Lim CJ, Watanabe N, Soriani A, Ratnikov B, Calderwood DA, Puzon-McLaughlin W, Lafuente EM, Boussiotis VA, Shattil SJ, Ginsberg MH. Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3. Current Biology : Cb. 16: 1796-806. PMID 16979556 DOI: 10.1016/J.Cub.2006.08.035  0.546
2006 Monniaux D, Huet-Calderwood C, Le Bellego F, Fabre S, Monget P, Calderwood DA. Integrins in the ovary. Seminars in Reproductive Medicine. 24: 251-61. PMID 16944422 DOI: 10.1055/S-2006-948554  0.558
2006 Kiema T, Lad Y, Jiang P, Oxley CL, Baldassarre M, Wegener KL, Campbell ID, Ylänne J, Calderwood DA. The molecular basis of filamin binding to integrins and competition with talin. Molecular Cell. 21: 337-47. PMID 16455489 DOI: 10.1016/J.Molcel.2006.01.011  0.811
2004 Calderwood DA. Talin controls integrin activation Biochemical Society Transactions. 32: 434-437. PMID 15157154 DOI: 10.1042/Bst0320434  0.57
2004 Calderwood DA, Tai V, Di Paolo G, De Camilli P, Ginsberg MH. Competition for talin results in trans-dominant inhibition of integrin activation. The Journal of Biological Chemistry. 279: 28889-95. PMID 15143061 DOI: 10.1074/Jbc.M402161200  0.512
2004 Calderwood DA. Integrin activation. Journal of Cell Science. 117: 657-66. PMID 14754902 DOI: 10.1242/jcs.01014  0.516
2004 Kloeker S, Major MB, Calderwood DA, Ginsberg MH, Jones DA, Beckerle MC. The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion. The Journal of Biological Chemistry. 279: 6824-33. PMID 14634021 DOI: 10.1074/Jbc.M307978200  0.449
2003 Tadokoro S, Shattil SJ, Eto K, Tai V, Liddington RC, de Pereda JM, Ginsberg MH, Calderwood DA. Talin binding to integrin beta tails: a final common step in integrin activation. Science (New York, N.Y.). 302: 103-6. PMID 14526080 DOI: 10.1126/Science.1086652  0.535
2003 Calderwood DA, Ginsberg MH. Talin forges the links between integrins and actin. Nature Cell Biology. 5: 694-7. PMID 12894175 DOI: 10.1038/Ncb0803-694  0.513
2003 Ulmer TS, Calderwood DA, Ginsberg MH, Campbell ID. Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit. Biochemistry. 42: 8307-12. PMID 12846579 DOI: 10.1021/Bi034384S  0.418
2003 Calderwood DA, Fujioka Y, de Pereda JM, García-Alvarez B, Nakamoto T, Margolis B, McGlade CJ, Liddington RC, Ginsberg MH. Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling. Proceedings of the National Academy of Sciences of the United States of America. 100: 2272-7. PMID 12606711 DOI: 10.1073/Pnas.262791999  0.506
2003 García-Alvarez B, de Pereda JM, Calderwood DA, Ulmer TS, Critchley D, Campbell ID, Ginsberg MH, Liddington RC. Structural determinants of integrin recognition by talin. Molecular Cell. 11: 49-58. PMID 12535520 DOI: 10.1016/S1097-2765(02)00823-7  0.551
2002 Woodside DG, Obergfell A, Talapatra A, Calderwood DA, Shattil SJ, Ginsberg MH. The N-terminal SH2 domains of Syk and ZAP-70 mediate phosphotyrosine-independent binding to integrin beta cytoplasmic domains. The Journal of Biological Chemistry. 277: 39401-8. PMID 12171941 DOI: 10.1074/Jbc.M207657200  0.451
2002 Calderwood DA, Yan B, de Pereda JM, Alvarez BG, Fujioka Y, Liddington RC, Ginsberg MH. The phosphotyrosine binding-like domain of talin activates integrins. The Journal of Biological Chemistry. 277: 21749-58. PMID 11932255 DOI: 10.1074/Jbc.M111996200  0.455
2001 Calderwood DA, Huttenlocher A, Kiosses WB, Rose DM, Woodside DG, Schwartz MA, Ginsberg MH. Increased filamin binding to β-integrin cytoplasmic domains inhibits cell migration Nature Cell Biology. 3: 1060-1068. PMID 11781567 DOI: 10.1038/Ncb1201-1060  0.58
2001 Formstecher E, Ramos JW, Fauquet M, Calderwood DA, Hsieh JC, Canton B, Nguyen XT, Barnier JV, Camonis J, Ginsberg MH, Chneiweiss H. PEA-15 Mediates Cytoplasmic Sequestration of ERK MAP Kinase Developmental Cell. 1: 239-250. PMID 11702783 DOI: 10.1016/S1534-5807(01)00035-1  0.392
2001 Yan B, Calderwood DA, Yaspan B, Ginsberg MH. Calpain Cleavage Promotes Talin Binding to the β3 Integrin Cytoplasmic Domain Journal of Biological Chemistry. 276: 28164-28170. PMID 11382782 DOI: 10.1074/Jbc.M104161200  0.473
2001 Fenczik CA, Zent R, Dellos M, Calderwood DA, Satriano J, Kelly C, Ginsberg MH. Distinct Domains of CD98hc Regulate Integrins and Amino Acid Transport Journal of Biological Chemistry. 276: 8746-8752. PMID 11121428 DOI: 10.1074/Jbc.M011239200  0.411
2000 Liu S, Calderwood DA, Ginsberg MH. Integrin cytoplasmic domain-binding proteins Journal of Cell Science. 113: 3563-3571. PMID 11017872  0.523
2000 Calderwood DA, Shattil SJ, Ginsberg MH. Integrins and actin filaments: Reciprocal regulation of cell adhesion and signaling Journal of Biological Chemistry. 275: 22607-22610. PMID 10801899 DOI: 10.1074/Jbc.R900037199  0.513
2000 Zent R, Fenczik CA, Calderwood DA, Liu S, Dellos M, Ginsberg MH. Class- and splice variant-specific association of CD98 with integrin β cytoplasmic domains Journal of Biological Chemistry. 275: 5059-5064. PMID 10671548 DOI: 10.1074/Jbc.275.7.5059  0.379
1999 Calderwood DA, Zent R, Grant R, Rees DJG, Hynes RO, Ginsberg MH. The talin head domain binds to integrin β subunit cytoplasmic tails and regulates integrin activation Journal of Biological Chemistry. 274: 28071-28074. PMID 10497155 DOI: 10.1074/Jbc.274.40.28071  0.521
1997 Davies D, Tuckwell DS, Calderwood DA, Weston SA, Takigawa M, Humphries MJ. Molecular characterisation of integrin-procollagen C-propeptide interactions. European Journal of Biochemistry / Febs. 246: 274-82. PMID 9208915 DOI: 10.1111/J.1432-1033.1997.T01-1-00274.X  0.496
1997 Calderwood DA, Tuckwell DS, Eble J, Kühn K, Humphries MJ. The integrin alpha1 A-domain is a ligand binding site for collagens and laminin. The Journal of Biological Chemistry. 272: 12311-7. PMID 9139675 DOI: 10.1074/Jbc.272.19.12311  0.469
1995 Calderwood DA, Tuckwell DS, Humphries MJ. Specificity of integrin I-domain-ligand binding. Biochemical Society Transactions. 23: 504S. PMID 8654689 DOI: 10.1042/Bst023504S  0.45
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