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132 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Rabadan MA, De La Cruz ED, Rao SB, Chen Y, Gong C, Crabtree G, Xu B, Markx S, Gogos JA, Yuste R, Tomer R. An in vitro model of neuronal ensembles. Nature Communications. 13: 3340. PMID 35680927 DOI: 10.1038/s41467-022-31073-1  0.806
2021 Park AJ, Harris AZ, Martyniuk KM, Chang CY, Abbas AI, Lowes DC, Kellendonk C, Gogos JA, Gordon JA. Reset of hippocampal-prefrontal circuitry facilitates learning. Nature. PMID 33627872 DOI: 10.1038/s41586-021-03272-1  0.672
2020 Hamm JP, Shymkiv Y, Mukai J, Gogos JA, Yuste R. Aberrant Cortical Ensembles and Schizophrenia-like Sensory Phenotypes in Setd1a Mice. Biological Psychiatry. PMID 32143831 DOI: 10.1016/J.Biopsych.2020.01.004  0.47
2019 Mukai J, Cannavò E, Crabtree GW, Sun Z, Diamantopoulou A, Thakur P, Chang CY, Cai Y, Lomvardas S, Takata A, Xu B, Gogos JA. Recapitulation and Reversal of Schizophrenia-Related Phenotypes in Setd1a-Deficient Mice. Neuron. PMID 31606247 DOI: 10.1016/J.Neuron.2019.09.014  0.851
2019 Gogos JA, Crabtree G, Diamantopoulou A. The abiding relevance of mouse models of rare mutations to psychiatric neuroscience and therapeutics. Schizophrenia Research. PMID 30987923 DOI: 10.1016/J.Schres.2019.03.018  0.733
2019 Gokhale A, Hartwig C, Freeman AAH, Bassell JL, Zlatic SA, Sapp Savas C, Vadlamudi T, Abudulai F, Pham TT, Crocker A, Werner E, Wen Z, Repetto GM, Gogos JA, Claypool SM, et al. Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30833507 DOI: 10.1523/Jneurosci.1983-18.2019  0.354
2019 Diamantopoulou A, Gogos JA. Neurocognitive and Perceptual Processing in Genetic Mouse Models of Schizophrenia: Emerging Lessons. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 1073858418819435. PMID 30654694 DOI: 10.1177/1073858418819435  0.74
2018 Sun Z, Williams DJ, Xu B, Gogos JA. Altered function and maturation of primary cortical neurons from a 22q11.2 deletion mouse model of schizophrenia. Translational Psychiatry. 8: 85. PMID 29666363 DOI: 10.1038/S41398-018-0132-8  0.36
2017 Tamura M, Spellman TJ, Rosen AM, Gogos JA, Gordon JA. Hippocampal-prefrontal theta-gamma coupling during performance of a spatial working memory task. Nature Communications. 8: 2182. PMID 29259151 DOI: 10.1038/s41467-017-02108-9  0.581
2017 Notaras M, Du X, Gogos J, van den Buuse M, Hill RA. The BDNF Val66Met polymorphism regulates glucocorticoid-induced corticohippocampal remodeling and behavioral despair. Translational Psychiatry. 7: e1233. PMID 28926000 DOI: 10.1038/tp.2017.205  0.348
2017 Zaremba JD, Diamantopoulou A, Danielson NB, Grosmark AD, Kaifosh PW, Bowler JC, Liao Z, Sparks FT, Gogos JA, Losonczy A. Impaired hippocampal place cell dynamics in a mouse model of the 22q11.2 deletion. Nature Neuroscience. PMID 28869582 DOI: 10.1038/Nn.4634  0.797
2017 Diamantopoulou A, Sun Z, Mukai J, Xu B, Fenelon K, Karayiorgou M, Gogos JA. Loss-of-function mutation in Mirta22/Emc10 rescues specific schizophrenia-related phenotypes in a mouse model of the 22q11.2 deletion. Proceedings of the National Academy of Sciences of the United States of America. PMID 28696314 DOI: 10.1073/Pnas.1615719114  0.843
2017 Choi SJ, Mukai J, Kvajo M, Xu B, Diamantopoulou A, Pitychoutis PM, Gou B, Gogos JA, Zhang H. A Schizophrenia-Related Deletion Leads to KCNQ2-Dependent Abnormal Dopaminergic Modulation of Prefrontal Cortical Interneuron Activity. Cerebral Cortex (New York, N.Y. : 1991). 1-17. PMID 28525574 DOI: 10.1093/Cercor/Bhx123  0.823
2017 Hamm JP, Peterka DS, Gogos JA, Yuste R. Altered Cortical Ensembles in Mouse Models of Schizophrenia. Neuron. 94: 153-167.e8. PMID 28384469 DOI: 10.1016/J.Neuron.2017.03.019  0.445
2017 Crabtree GW, Sun Z, Kvajo M, Broek JA, Fénelon K, McKellar H, Xiao L, Xu B, Bahn S, O'Donnell JM, Gogos JA. Alteration of neuronal excitability and short-term synaptic plasticity in the prefrontal cortex of a mouse model of mental illness. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28283561 DOI: 10.1523/Jneurosci.4345-15.2017  0.823
2017 Qi Y, Zhang XJ, Renier N, Wu Z, Atkin T, Sun Z, Ozair MZ, Tchieu J, Zimmer B, Fattahi F, Ganat Y, Azevedo R, Zeltner N, Brivanlou AH, Karayiorgou M, ... Gogos J, et al. Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. Nature Biotechnology. PMID 28112759 DOI: 10.1038/Nbt.3777  0.784
2017 Hamm J, Gogos J. 222. Abnormal Neocortical Ensemble Activity in Pharmacological and Genetic Mouse Models Supports an Attractor Pathophysiology of Schizophrenia Schizophrenia Bulletin. 43: S112-S112. DOI: 10.1093/Schbul/Sbx021.300  0.504
2016 Crabtree GW, Park AJ, Gordon JA, Gogos JA. Cytosolic Accumulation of L-Proline Disrupts GABA-Ergic Transmission through GAD Blockade. Cell Reports. 17: 570-582. PMID 27705802 DOI: 10.1016/J.Celrep.2016.09.029  0.626
2016 Hartung H, Cichon N, De Feo V, Riemann S, Schildt S, Lindemann C, Mulert C, Gogos JA, Hanganu-Opatz IL. From Shortage to Surge: A Developmental Switch in Hippocampal-Prefrontal Coupling in a Gene-Environment Model of Neuropsychiatric Disorders. Cerebral Cortex (New York, N.Y. : 1991). PMID 27613435 DOI: 10.1093/Cercor/Bhw274  0.306
2016 Notaras MJ, Hill RA, Gogos JA, van den Buuse M. BDNF Val66Met Genotype Interacts With a History of Simulated Stress Exposure to Regulate Sensorimotor Gating and Startle Reactivity. Schizophrenia Bulletin. PMID 27262112 DOI: 10.1093/schbul/sbw077  0.343
2016 Wesseling H, Xu B, Want EJ, Holmes E, Guest PC, Karayiorgou M, Gogos JA, Bahn S. System-based proteomic and metabonomic analysis of the Df(16)A(+/-) mouse identifies potential miR-185 targets and molecular pathway alterations. Molecular Psychiatry. PMID 27001617 DOI: 10.1038/Mp.2016.27  0.736
2016 Takata A, Ionita-Laza I, Gogos JA, Xu B, Karayiorgou M. De Novo Synonymous Mutations in Regulatory Elements Contribute to the Genetic Etiology of Autism and Schizophrenia. Neuron. 89: 940-7. PMID 26938441 DOI: 10.1016/J.Neuron.2016.02.024  0.725
2016 Tamura M, Mukai J, Gordon JA, Gogos JA. Developmental Inhibition of Gsk3 Rescues Behavioral and Neurophysiological Deficits in a Mouse Model of Schizophrenia Predisposition. Neuron. PMID 26898776 DOI: 10.1016/j.neuron.2016.01.025  0.593
2016 Piskorowski RA, Nasrallah K, Diamantopoulou A, Mukai J, Hassan SI, Siegelbaum SA, Gogos JA, Chevaleyre V. Age-Dependent Specific Changes in Area CA2 of the Hippocampus and Social Memory Deficit in a Mouse Model of the 22q11.2 Deletion Syndrome. Neuron. 89: 163-176. PMID 26748091 DOI: 10.1016/J.Neuron.2015.11.036  0.716
2015 Barr I, Weitz SH, Atkin T, Hsu P, Karayiorgou M, Gogos JA, Weiss S, Guo F. Cobalt(III) Protoporphyrin Activates the DGCR8 Protein and Can Compensate microRNA Processing Deficiency. Chemistry & Biology. 22: 793-802. PMID 26091172 DOI: 10.1016/J.Chembiol.2015.05.015  0.774
2015 Levy RJ, Kvajo M, Li Y, Tsvetkov E, Dong W, Yoshikawa Y, Kataoka T, Bolshakov VY, Karayiorgou M, Gogos JA. Deletion of Rapgef6, a candidate schizophrenia susceptibility gene, disrupts amygdala function in mice. Translational Psychiatry. 5: e577. PMID 26057047 DOI: 10.1038/Tp.2015.75  0.846
2015 Spellman T, Rigotti M, Ahmari SE, Fusi S, Gogos JA, Gordon JA. Hippocampal-prefrontal input supports spatial encoding in working memory. Nature. 522: 309-14. PMID 26053122 DOI: 10.1038/Nature14445  0.396
2015 Mukai J, Tamura M, Fénelon K, Rosen AM, Spellman TJ, Kang R, MacDermott AB, Karayiorgou M, Gordon JA, Gogos JA. Molecular substrates of altered axonal growth and brain connectivity in a mouse model of schizophrenia. Neuron. 86: 680-95. PMID 25913858 DOI: 10.1016/J.Neuron.2015.04.003  0.827
2015 Hsu PK, Xu B, Mukai J, Karayiorgou M, Gogos JA. The BDNF Val66Met variant affects gene expression through miR-146b. Neurobiology of Disease. 77: 228-37. PMID 25771167 DOI: 10.1016/J.Nbd.2015.03.004  0.78
2014 Gómez-Sintes R, Kvajo M, Gogos JA, Lucas JJ. Mice with a naturally occurring DISC1 mutation display a broad spectrum of behaviors associated to psychiatric disorders. Frontiers in Behavioral Neuroscience. 8: 253. PMID 25126062 DOI: 10.3389/Fnbeh.2014.00253  0.798
2014 Karayannis T, Au E, Patel JC, Kruglikov I, Markx S, Delorme R, Héron D, Salomon D, Glessner J, Restituito S, Gordon A, Rodriguez-Murillo L, Roy NC, Gogos JA, Rudy B, et al. Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission. Nature. 511: 236-40. PMID 24870235 DOI: 10.1038/Nature13248  0.817
2014 Takata A, Xu B, Ionita-Laza I, Roos JL, Gogos JA, Karayiorgou M. Loss-of-function variants in schizophrenia risk and SETD1A as a candidate susceptibility gene. Neuron. 82: 773-80. PMID 24853937 DOI: 10.1016/J.Neuron.2014.04.043  0.771
2014 Ellegood J, Markx S, Lerch JP, Steadman PE, Genç C, Provenzano F, Kushner SA, Henkelman RM, Karayiorgou M, Gogos JA. A highly specific pattern of volumetric brain changes due to 22q11.2 deletions in both mice and humans. Molecular Psychiatry. 19: 6. PMID 24362540 DOI: 10.1038/Mp.2013.179  0.792
2014 Ionita-Laza I, Xu B, Makarov V, Buxbaum JD, Roos JL, Gogos JA, Karayiorgou M. Scan statistic-based analysis of exome sequencing data identifies FAN1 at 15q13.3 as a susceptibility gene for schizophrenia and autism. Proceedings of the National Academy of Sciences of the United States of America. 111: 343-8. PMID 24344280 DOI: 10.1073/Pnas.1309475110  0.735
2014 Rodriguez-Murillo L, Xu B, Roos JL, Abecasis GR, Gogos JA, Karayiorgou M. Fine mapping on chromosome 13q32-34 and brain expression analysis implicates MYO16 in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 934-43. PMID 24141571 DOI: 10.1038/Npp.2013.293  0.752
2014 Ellegood J, Markx S, Lerch JP, Steadman PE, Genç C, Provenzano F, Kushner SA, Henkelman RM, Karayiorgou M, Gogos JA. Neuroanatomical phenotypes in a mouse model of the 22q11.2 microdeletion. Molecular Psychiatry. 19: 99-107. PMID 23999526 DOI: 10.1038/Mp.2013.112  0.83
2013 Fénelon K, Xu B, Lai CS, Mukai J, Markx S, Stark KL, Hsu PK, Gan WB, Fischbach GD, MacDermott AB, Karayiorgou M, Gogos JA. The pattern of cortical dysfunction in a mouse model of a schizophrenia-related microdeletion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 14825-39. PMID 24027283 DOI: 10.1523/Jneurosci.1611-13.2013  0.823
2013 Lepagnol-Bestel AM, Kvajo M, Karayiorgou M, Simonneau M, Gogos JA. A Disc1 mutation differentially affects neurites and spines in hippocampal and cortical neurons. Molecular and Cellular Neurosciences. 54: 84-92. PMID 23396153 DOI: 10.1016/J.Mcn.2013.01.006  0.822
2013 Xu B, Hsu PK, Stark KL, Karayiorgou M, Gogos JA. Derepression of a neuronal inhibitor due to miRNA dysregulation in a schizophrenia-related microdeletion. Cell. 152: 262-75. PMID 23332760 DOI: 10.1016/J.Cell.2012.11.052  0.797
2012 Gilman SR, Chang J, Xu B, Bawa TS, Gogos JA, Karayiorgou M, Vitkup D. Diverse types of genetic variation converge on functional gene networks involved in schizophrenia. Nature Neuroscience. 15: 1723-8. PMID 23143521 DOI: 10.1038/Nn.3261  0.771
2012 Xu B, Ionita-Laza I, Roos JL, Boone B, Woodrick S, Sun Y, Levy S, Gogos JA, Karayiorgou M. De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia. Nature Genetics. 44: 1365-9. PMID 23042115 DOI: 10.1038/Ng.2446  0.757
2012 Karayiorgou M, Flint J, Gogos JA, Malenka RC. The best of times, the worst of times for psychiatric disease. Nature Neuroscience. 15: 811-2. PMID 22627793 DOI: 10.1038/Nn.3115  0.661
2012 Behan AT, Hryniewiecka M, O'Tuathaigh CM, Kinsella A, Cannon M, Karayiorgou M, Gogos JA, Waddington JL, Cotter DR. Chronic adolescent exposure to delta-9-tetrahydrocannabinol in COMT mutant mice: impact on indices of dopaminergic, endocannabinoid and GABAergic pathways. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1773-83. PMID 22434221 DOI: 10.1038/Npp.2012.24  0.727
2012 Xu B, Hsu PK, Karayiorgou M, Gogos JA. MicroRNA dysregulation in neuropsychiatric disorders and cognitive dysfunction. Neurobiology of Disease. 46: 291-301. PMID 22406400 DOI: 10.1016/J.Nbd.2012.02.016  0.754
2012 Levy RJ, Xu B, Gogos JA, Karayiorgou M. Copy number variation and psychiatric disease risk. Methods in Molecular Biology (Clifton, N.J.). 838: 97-113. PMID 22228008 DOI: 10.1007/978-1-61779-507-7_4  0.798
2012 Desbonnet L, Tighe O, Karayiorgou M, Gogos JA, Waddington JL, O'Tuathaigh CM. Physiological and behavioural responsivity to stress and anxiogenic stimuli in COMT-deficient mice. Behavioural Brain Research. 228: 351-8. PMID 22192380 DOI: 10.1016/J.Bbr.2011.12.014  0.674
2012 Arguello PA, Gogos JA. Genetic and cognitive windows into circuit mechanisms of psychiatric disease. Trends in Neurosciences. 35: 3-13. PMID 22177981 DOI: 10.1016/j.tins.2011.11.007  0.765
2012 O'Tuathaigh CM, Clarke G, Walsh J, Desbonnet L, Petit E, O'Leary C, Tighe O, Clarke N, Karayiorgou M, Gogos JA, Dinan TG, Cryan JF, Waddington JL. Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1331-42. PMID 22074909 DOI: 10.1017/S1461145711001581  0.739
2012 Rodriguez-Murillo L, Gogos JA, Karayiorgou M. The genetic architecture of schizophrenia: new mutations and emerging paradigms. Annual Review of Medicine. 63: 63-80. PMID 22034867 DOI: 10.1016/S0920-9964(12)70096-8  0.762
2012 Schendzielorz N, Männistö PT, Karayiorgou M, Gogos JA, Raasmaja A. A transient inhibition and permanent lack of catechol-O-methyltransferase have minor effects on feeding pattern of female rodents. Basic & Clinical Pharmacology & Toxicology. 110: 307-13. PMID 21851556 DOI: 10.1111/J.1742-7843.2011.00783.X  0.691
2012 Kvajo M, McKellar H, Gogos JA. Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models. Neuroscience. 211: 136-64. PMID 21821099 DOI: 10.1016/J.Neuroscience.2011.07.051  0.832
2011 Kvajo M, McKellar H, Drew LJ, Lepagnol-Bestel AM, Xiao L, Levy RJ, Blazeski R, Arguello PA, Lacefield CO, Mason CA, Simonneau M, O'Donnell JM, MacDermott AB, Karayiorgou M, Gogos JA. Altered axonal targeting and short-term plasticity in the hippocampus of Disc1 mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 108: E1349-58. PMID 22049344 DOI: 10.1073/pnas.1114113108  0.808
2011 Xu B, Roos JL, Dexheimer P, Boone B, Plummer B, Levy S, Gogos JA, Karayiorgou M. Exome sequencing supports a de novo mutational paradigm for schizophrenia. Nature Genetics. 43: 864-8. PMID 21822266 DOI: 10.1038/Ng.902  0.758
2011 Drew LJ, Stark KL, Fénelon K, Karayiorgou M, Macdermott AB, Gogos JA. Evidence for altered hippocampal function in a mouse model of the human 22q11.2 microdeletion. Molecular and Cellular Neurosciences. 47: 293-305. PMID 21635953 DOI: 10.1016/J.Mcn.2011.05.008  0.836
2011 Fénelon K, Mukai J, Xu B, Hsu PK, Drew LJ, Karayiorgou M, Fischbach GD, Macdermott AB, Gogos JA. Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. 108: 4447-52. PMID 21368174 DOI: 10.1073/Pnas.1101219108  0.829
2011 Drew LJ, Crabtree GW, Markx S, Stark KL, Chaverneff F, Xu B, Mukai J, Fenelon K, Hsu PK, Gogos JA, Karayiorgou M. The 22q11.2 microdeletion: fifteen years of insights into the genetic and neural complexity of psychiatric disorders. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 29: 259-81. PMID 20920576 DOI: 10.1016/J.Ijdevneu.2010.09.007  0.823
2011 Arguello PA, Gogos JA. Psychiatric genetics and the generation of mutant animal models Neuromethods. 59: 189-209. DOI: 10.1007/978-1-61779-157-4_8  0.753
2011 Lipska BK, Gogos JA. Animal Models of Schizophrenia Schizophrenia: Third Edition. 462-481. DOI: 10.1002/9781444327298.ch22  0.354
2010 Kvajo M, McKellar H, Gogos JA. Molecules, signaling, and schizophrenia. Current Topics in Behavioral Neurosciences. 4: 629-56. PMID 21312416 DOI: 10.1007/7854_2010_41  0.823
2010 O'Tuathaigh CM, Hryniewiecka M, Behan A, Tighe O, Coughlan C, Desbonnet L, Cannon M, Karayiorgou M, Gogos JA, Cotter DR, Waddington JL. Chronic adolescent exposure to Δ-9-tetrahydrocannabinol in COMT mutant mice: impact on psychosis-related and other phenotypes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2262-73. PMID 20631688 DOI: 10.1038/Npp.2010.100  0.677
2010 Käenmäki M, Tammimäki A, Myöhänen T, Pakarinen K, Amberg C, Karayiorgou M, Gogos JA, Männistö PT. Quantitative role of COMT in dopamine clearance in the prefrontal cortex of freely moving mice. Journal of Neurochemistry. 114: 1745-55. PMID 20626558 DOI: 10.1111/J.1471-4159.2010.06889.X  0.708
2010 Walsh J, Tighe O, Lai D, Harvey R, Karayiorgou M, Gogos JA, Waddington JL, O'Tuathaigh CM. Disruption of thermal nociceptive behaviour in mice mutant for the schizophrenia-associated genes NRG1, COMT and DISC1. Brain Research. 1348: 114-9. PMID 20561508 DOI: 10.1016/J.Brainres.2010.06.027  0.722
2010 Karayiorgou M, Simon TJ, Gogos JA. 22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia. Nature Reviews. Neuroscience. 11: 402-16. PMID 20485365 DOI: 10.1038/Nrn2841  0.763
2010 Xu B, Karayiorgou M, Gogos JA. MicroRNAs in psychiatric and neurodevelopmental disorders. Brain Research. 1338: 78-88. PMID 20388499 DOI: 10.1016/J.Brainres.2010.03.109  0.714
2010 Sigurdsson T, Stark KL, Karayiorgou M, Gogos JA, Gordon JA. Impaired hippocampal-prefrontal synchrony in a genetic mouse model of schizophrenia. Nature. 464: 763-7. PMID 20360742 DOI: 10.1038/Nature08855  0.817
2010 Arguello PA, Markx S, Gogos JA, Karayiorgou M. Development of animal models for schizophrenia. Disease Models & Mechanisms. 3: 22-6. PMID 20075378 DOI: 10.1242/Dmm.003996  0.846
2010 Arguello PA, Gogos JA. Cognition in mouse models of schizophrenia susceptibility genes. Schizophrenia Bulletin. 36: 289-300. PMID 20026558 DOI: 10.1093/schbul/sbp153  0.793
2010 Karayiorgou M, Gogos JA. COPY NUMBER VARIATION IN SCHIZOPHRENIA: MODELING 22Q11 Schizophrenia Research. 117: 108-109. DOI: 10.1016/J.Schres.2010.02.020  0.755
2009 Käenmäki M, Tammimäki A, Garcia-Horsman JA, Myöhänen T, Schendzielorz N, Karayiorgou M, Gogos JA, Männistö PT. Importance of membrane-bound catechol-O-methyltransferase in L-DOPA metabolism: a pharmacokinetic study in two types of Comt gene modified mice. British Journal of Pharmacology. 158: 1884-94. PMID 19930170 DOI: 10.1111/J.1476-5381.2009.00494.X  0.7
2009 Xu B, Woodroffe A, Rodriguez-Murillo L, Roos JL, van Rensburg EJ, Abecasis GR, Gogos JA, Karayiorgou M. Elucidating the genetic architecture of familial schizophrenia using rare copy number variant and linkage scans. Proceedings of the National Academy of Sciences of the United States of America. 106: 16746-51. PMID 19805367 DOI: 10.1073/Pnas.0908584106  0.745
2009 Stark KL, Burt RA, Gogos JA, Karayiorgou M. Analysis of prepulse inhibition in mouse lines overexpressing 22q11.2 orthologues. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 983-9. PMID 19519974 DOI: 10.1017/S1461145709000492  0.727
2009 Tenorio-Laranga J, Männistö PT, Karayiorgou M, Gogos JA, García-Horsman JA. Sex-dependent compensated oxidative stress in the mouse liver upon deletion of catechol O-methyltransferase. Biochemical Pharmacology. 77: 1541-52. PMID 19426692 DOI: 10.1016/J.Bcp.2009.02.004  0.674
2008 Mukai J, Dhilla A, Drew LJ, Stark KL, Cao L, MacDermott AB, Karayiorgou M, Gogos JA. Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion. Nature Neuroscience. 11: 1302-10. PMID 18836441 DOI: 10.1038/Nn.2204  0.824
2008 Kambur O, Männistö PT, Viljakka K, Reenilä I, Lemberg K, Kontinen VK, Karayiorgou M, Gogos JA, Kalso E. Stress-induced analgesia and morphine responses are changed in catechol-O-methyltransferase-deficient male mice. Basic & Clinical Pharmacology & Toxicology. 103: 367-73. PMID 18834357 DOI: 10.1111/J.1742-7843.2008.00289.X  0.663
2008 Tammimäki A, Forsberg MM, Karayiorgou M, Gogos JA, Männistö PT. Increase in free choice oral ethanol self-administration in catechol-o-methyltransferase gene-disrupted male mice. Basic & Clinical Pharmacology & Toxicology. 103: 297-304. PMID 18684228 DOI: 10.1111/J.1742-7843.2008.00267.X  0.661
2008 Babovic D, O'Tuathaigh CM, O'Connor AM, O'Sullivan GJ, Tighe O, Croke DT, Karayiorgou M, Gogos JA, Cotter D, Waddington JL. Phenotypic characterization of cognition and social behavior in mice with heterozygous versus homozygous deletion of catechol-O-methyltransferase. Neuroscience. 155: 1021-9. PMID 18674597 DOI: 10.1016/J.Neuroscience.2008.07.006  0.72
2008 Xu B, Roos JL, Levy S, van Rensburg EJ, Gogos JA, Karayiorgou M. Strong association of de novo copy number mutations with sporadic schizophrenia. Nature Genetics. 40: 880-5. PMID 18511947 DOI: 10.1038/Ng.162  0.76
2008 Arguello PA, Gogos JA. A signaling pathway AKTing up in schizophrenia. The Journal of Clinical Investigation. 118: 2018-21. PMID 18497888 DOI: 10.1172/JCI35931  0.781
2008 Stark KL, Xu B, Bagchi A, Lai WS, Liu H, Hsu R, Wan X, Pavlidis P, Mills AA, Karayiorgou M, Gogos JA. Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nature Genetics. 40: 751-60. PMID 18469815 DOI: 10.1038/Ng.138  0.805
2008 Kvajo M, McKellar H, Arguello PA, Drew LJ, Moore H, MacDermott AB, Karayiorgou M, Gogos JA. A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition. Proceedings of the National Academy of Sciences of the United States of America. 105: 7076-81. PMID 18458327 DOI: 10.1073/Pnas.0802615105  0.828
2008 Kvajo M, Dhilla A, Swor DE, Karayiorgou M, Gogos JA. Evidence implicating the candidate schizophrenia/bipolar disorder susceptibility gene G72 in mitochondrial function. Molecular Psychiatry. 13: 685-96. PMID 17684499 DOI: 10.1038/Sj.Mp.4002052  0.802
2008 Arguello A, Moore H, Karayiorgou M, Gogos J. A MUTATION IN MOUSE DISC1 RESEMBLING A SCHIZOPHRENIA RISK ALLELE LEADS TO IMPAIRMENTS OF HIGHER ORDER COGNITION Schizophrenia Research. 102: 57. DOI: 10.1016/S0920-9964(08)70177-4  0.757
2007 Hsu R, Woodroffe A, Lai WS, Cook MN, Mukai J, Dunning JP, Swanson DJ, Roos JL, Abecasis GR, Karayiorgou M, Gogos JA. Nogo Receptor 1 (RTN4R) as a candidate gene for schizophrenia: analysis using human and mouse genetic approaches. Plos One. 2: e1234. PMID 18043741 DOI: 10.1371/Journal.Pone.0001234  0.845
2007 Yavich L, Forsberg MM, Karayiorgou M, Gogos JA, Männistö PT. Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10196-209. PMID 17881525 DOI: 10.1523/Jneurosci.0665-07.2007  0.679
2007 Babovic D, O'Tuathaigh CM, O'Sullivan GJ, Clifford JJ, Tighe O, Croke DT, Karayiorgou M, Gogos JA, Cotter D, Waddington JL. Exploratory and habituation phenotype of heterozygous and homozygous COMT knockout mice. Behavioural Brain Research. 183: 236-9. PMID 17707921 DOI: 10.1016/J.Bbr.2007.07.006  0.775
2007 Cao L, Dhilla A, Mukai J, Blazeski R, Lodovichi C, Mason CA, Gogos JA. Genetic modulation of BDNF signaling affects the outcome of axonal competition in vivo. Current Biology : Cb. 17: 911-21. PMID 17493809 DOI: 10.1016/j.cub.2007.04.040  0.721
2007 Gogos JA. Schizophrenia susceptibility genes: in search of a molecular logic and novel drug targets for a devastating disorder. International Review of Neurobiology. 78: 397-422. PMID 17349868 DOI: 10.1016/S0074-7742(06)78013-8  0.408
2007 Arguello PA, Gogos JA. Schizophrenia: Modeling a complex psychiatric disorder Drug Discovery Today: Disease Models. 3: 319-325. DOI: 10.1016/j.ddmod.2006.12.004  0.786
2006 Lai WS, Xu B, Westphal KG, Paterlini M, Olivier B, Pavlidis P, Karayiorgou M, Gogos JA. Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning. Proceedings of the National Academy of Sciences of the United States of America. 103: 16906-11. PMID 17077150 DOI: 10.1073/Pnas.0604994103  0.803
2006 Arguello PA, Gogos JA. Modeling madness in mice: one piece at a time. Neuron. 52: 179-96. PMID 17015235 DOI: 10.1016/j.neuron.2006.09.023  0.766
2006 Gogos JA, Gerber DJ. Schizophrenia susceptibility genes: emergence of positional candidates and future directions. Trends in Pharmacological Sciences. 27: 226-33. PMID 16530856 DOI: 10.1016/j.tips.2006.02.005  0.417
2006 Karayiorgou M, Gogos JA. Schizophrenia genetics: uncovering positional candidate genes. European Journal of Human Genetics : Ejhg. 14: 512-9. PMID 16493444 DOI: 10.1038/Sj.Ejhg.5201587  0.766
2006 Koike H, Arguello PA, Kvajo M, Karayiorgou M, Gogos JA. Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 3693-7. PMID 16484369 DOI: 10.1073/Pnas.0511189103  0.83
2006 Woodroffe A, Abecasis G, Roos JL, Gogos J, Karayiorgou M. Genome-Wide Linkage Scan and Follow-Up Association Analysis for Schizophrenia in an Afrikaner Founder Population American Journal of Epidemiology. 163: S126-S126. DOI: 10.1093/Aje/163.Suppl_11.S126-D  0.73
2005 Paterlini M, Zakharenko SS, Lai WS, Qin J, Zhang H, Mukai J, Westphal KG, Olivier B, Sulzer D, Pavlidis P, Siegelbaum SA, Karayiorgou M, Gogos JA. Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice. Nature Neuroscience. 8: 1586-94. PMID 16234811 DOI: 10.1038/Nn1562  0.819
2004 Karayiorgou M, Gogos JA. The molecular genetics of the 22q11-associated schizophrenia. Brain Research. Molecular Brain Research. 132: 95-104. PMID 15582150 DOI: 10.1016/J.Molbrainres.2004.09.029  0.784
2004 Forsberg MM, Juvonen RO, Helisalmi P, Leppänen J, Gogos JA, Karayiorgou M, Männistö PT. Lack of increased oxidative stress in catechol-O-methyltransferase (COMT)-deficient mice. Naunyn-Schmiedeberg's Archives of Pharmacology. 370: 279-89. PMID 15378229 DOI: 10.1007/S00210-004-0967-9  0.672
2004 Hall D, Gogos JA, Karayiorgou M. The contribution of three strong candidate schizophrenia susceptibility genes in demographically distinct populations. Genes, Brain, and Behavior. 3: 240-8. PMID 15248869 DOI: 10.1111/J.1601-183X.2004.00078.X  0.726
2004 Mukai J, Liu H, Burt RA, Swor DE, Lai WS, Karayiorgou M, Gogos JA. Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia. Nature Genetics. 36: 725-31. PMID 15184899 DOI: 10.1038/Ng1375  0.79
2004 Yu CR, Power J, Barnea G, O'Donnell S, Brown HE, Osborne J, Axel R, Gogos JA. Spontaneous neural activity is required for the establishment and maintenance of the olfactory sensory map. Neuron. 42: 553-66. PMID 15157418 DOI: 10.1016/S0896-6273(04)00224-7  0.78
2004 Eggan K, Baldwin K, Tackett M, Osborne J, Gogos J, Chess A, Axel R, Jaenisch R. Mice cloned from olfactory sensory neurons. Nature. 428: 44-9. PMID 14990966 DOI: 10.1038/Nature02375  0.786
2004 Emamian ES, Karayiorgou M, Gogos JA. Decreased phosphorylation of NMDA receptor type 1 at serine 897 in brains of patients with Schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1561-4. PMID 14973229 DOI: 10.1523/Jneurosci.4650-03.2004  0.73
2004 Abecasis GR, Burt RA, Hall D, Bochum S, Doheny KF, Lundy SL, Torrington M, Roos JL, Gogos JA, Karayiorgou M. Genomewide scan in families with schizophrenia from the founder population of Afrikaners reveals evidence for linkage and uniparental disomy on chromosome 1. American Journal of Human Genetics. 74: 403-17. PMID 14750073 DOI: 10.1086/381713  0.756
2004 Emamian ES, Hall D, Birnbaum MJ, Karayiorgou M, Gogos JA. Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia. Nature Genetics. 36: 131-7. PMID 14745448 DOI: 10.1038/Ng1296  0.759
2004 Karayiorgou M, Torrington M, Abecasis GR, Pretorius H, Robertson B, Kaliski S, Lay S, Sobin C, Möller N, Lundy SL, Blundell ML, Gogos JA, Roos JL. Phenotypic characterization and genealogical tracing in an Afrikaner schizophrenia database. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 124: 20-8. PMID 14681908 DOI: 10.1002/Ajmg.B.20090  0.713
2004 Huotari M, García-Horsman JA, Karayiorgou M, Gogos JA, Männistö PT. D-amphetamine responses in catechol-O-methyltransferase (COMT) disrupted mice. Psychopharmacology. 172: 1-10. PMID 14574438 DOI: 10.1007/S00213-003-1627-3  0.678
2003 Zacharia LC, Gogos JA, Karayiorgou M, Jackson EK, Gillespie DG, Barchiesi F, Dubey RK. Methoxyestradiols mediate the antimitogenic effects of 17beta-estradiol: direct evidence from catechol-O-methyltransferase-knockout mice. Circulation. 108: 2974-8. PMID 14662705 DOI: 10.1161/01.Cir.0000106900.66354.30  0.666
2003 Helkamaa T, Männistö PT, Rauhala P, Cheng ZJ, Finckenberg P, Huotari M, Gogos JA, Karayiorgou M, Mervaala EM. Resistance to salt-induced hypertension in catechol-O-methyltransferase-gene-disrupted mice. Journal of Hypertension. 21: 2365-74. PMID 14654758 DOI: 10.1097/00004872-200312000-00026  0.675
2003 Wijsman EM, Rosenthal EA, Hall D, Blundell ML, Sobin C, Heath SC, Williams R, Brownstein MJ, Gogos JA, Karayiorgou M. Genome-wide scan in a large complex pedigree with predominantly male schizophrenics from the island of Kosrae: evidence for linkage to chromosome 2q. Molecular Psychiatry. 8: 695-705, 643. PMID 12874606 DOI: 10.1038/Sj.Mp.4001356  0.752
2003 Gerber DJ, Hall D, Miyakawa T, Demars S, Gogos JA, Karayiorgou M, Tonegawa S. Evidence for association of schizophrenia with genetic variation in the 8p21.3 gene, PPP3CC, encoding the calcineurin gamma subunit. Proceedings of the National Academy of Sciences of the United States of America. 100: 8993-8. PMID 12851458 DOI: 10.1073/pnas.1432927100  0.78
2003 Hall D, Dhilla A, Charalambous A, Gogos JA, Karayiorgou M. Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder. American Journal of Human Genetics. 73: 370-6. PMID 12836135 DOI: 10.1086/377003  0.69
2003 Karayiorgou M, Gogos JA. Genes for schizophrenia. Lancet (London, England). 361: 1828-9; author reply. PMID 12781572 DOI: 10.1016/S0140-6736(03)13432-0  0.752
2002 Liu H, Abecasis GR, Heath SC, Knowles A, Demars S, Chen YJ, Roos JL, Rapoport JL, Gogos JA, Karayiorgou M. Genetic variation in the 22q11 locus and susceptibility to schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 99: 16859-64. PMID 12477929 DOI: 10.1073/Pnas.232186099  0.772
2002 Huotari M, Santha M, Lucas LR, Karayiorgou M, Gogos JA, Männistö PT. Effect of dopamine uptake inhibition on brain catecholamine levels and locomotion in catechol-O-methyltransferase-disrupted mice. The Journal of Pharmacology and Experimental Therapeutics. 303: 1309-16. PMID 12438556 DOI: 10.1124/Jpet.102.043042  0.689
2002 Odlind C, Reenilä I, Männistö PT, Juvonen R, Uhlén S, Gogos JA, Karayiorgou M, Hansell P. Reduced natriuretic response to acute sodium loading in COMT gene deleted mice. Bmc Physiology. 2: 14. PMID 12188925 DOI: 10.1186/1472-6793-2-14  0.688
2002 Hall D, Wijsman EM, Roos JL, Gogos JA, Karayiorgou M. Extended intermarker linkage disequilibrium in the Afrikaners. Genome Research. 12: 956-61. PMID 12045148 DOI: 10.1101/Gr.136202  0.673
2002 Liu H, Heath SC, Sobin C, Roos JL, Galke BL, Blundell ML, Lenane M, Robertson B, Wijsman EM, Rapoport JL, Gogos JA, Karayiorgou M. Genetic variation at the 22q11 PRODH2/DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 99: 3717-22. PMID 11891283 DOI: 10.1073/Pnas.042700699  0.777
2002 Huotari M, Gogos JA, Karayiorgou M, Koponen O, Forsberg M, Raasmaja A, Hyttinen J, Männistö PT. Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice. The European Journal of Neuroscience. 15: 246-56. PMID 11849292 DOI: 10.1046/J.0953-816X.2001.01856.X  0.704
2001 Gogos JA, Karayiorgou M. Model-free vs. model-based linkage analysis: A false dichotomy? American Journal of Medical Genetics - Neuropsychiatric Genetics. 105: 62-64. PMID 11425002 DOI: 10.1002/1096-8628(20010108)105:1<62::Aid-Ajmg1063>3.0.Co;2-C  0.674
2001 Gogos JA, Karayiorgou M. "Targeting" schizophrenia in mice. American Journal of Medical Genetics. 105: 50-2. PMID 11424997 DOI: 10.1002/1096-8628(20010108)105:1<50::Aid-Ajmg1058>3.0.Co;2-5  0.773
2000 Gogos JA, Osborne J, Nemes A, Mendelsohn M, Axel R. Genetic ablation and restoration of the olfactory topographic map. Cell. 103: 609-20. PMID 11106731 DOI: 10.1016/S0092-8674(00)00164-1  0.648
1999 Karayiorgou M, Sobin C, Blundell ML, Galke BL, Malinova L, Goldberg P, Ott J, Gogos JA. Family-based association studies support a sexually dimorphic effect of COMT and MAOA on genetic susceptibility to obsessive-compulsive disorder. Biological Psychiatry. 45: 1178-89. PMID 10331110 DOI: 10.1016/S0006-3223(98)00319-9  0.71
1999 Gogos JA, Santha M, Takacs Z, Beck KD, Luine V, Lucas LR, Nadler JV, Karayiorgou M. The gene encoding proline dehydrogenase modulates sensorimotor gating in mice. Nature Genetics. 21: 434-9. PMID 10192398 DOI: 10.1038/7777  0.751
1998 Gogos JA, Morgan M, Luine V, Santha M, Ogawa S, Pfaff D, Karayiorgou M. Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. Proceedings of the National Academy of Sciences of the United States of America. 95: 9991-6. PMID 9707588 DOI: 10.1073/Pnas.95.17.9991  0.704
1998 Karayiorgou M, Gogos JA, Galke BL, Wolyniec PS, Nestadt G, Antonarakis SE, Kazazian HH, Housman DE, Pulver AE. Identification of sequence variants and analysis of the role of the catechol-O-methyl-transferase gene in schizophrenia susceptibility. Biological Psychiatry. 43: 425-31. PMID 9532347 DOI: 10.1016/S0006-3223(97)00202-3  0.774
1997 Karayiorgou M, Gogos JA. A turning point in schizophrenia genetics. Neuron. 19: 967-79. PMID 9390512 DOI: 10.1016/S0896-6273(00)80390-6  0.757
1997 Karayiorgou M, Gogos JA. Dissecting the genetic complexity of schizophrenia. Molecular Psychiatry. 2: 211-23. PMID 9152985 DOI: 10.1038/Sj.Mp.4000271  0.772
1997 Karayiorgou M, Altemus M, Galke BL, Goldman D, Murphy DL, Ott J, Gogos JA. Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder. Proceedings of the National Academy of Sciences of the United States of America. 94: 4572-5. PMID 9114031 DOI: 10.1073/Pnas.94.9.4572  0.706
1997 Gogos JA, Lowry W, Karayiorgou M. Selection for retroviral insertions into regulated genes. Journal of Virology. 71: 1644-50. PMID 8995693 DOI: 10.1128/jvi.71.2.1644-1650.1997  0.667
1996 Karayiorgou M, Gogos JA, Galke BL, Jeffery JA, Nestadt G, Wolyniec PS, Antonarakis SE, Kazazian HH, Housman DE, Driscoll DA, Pulver AE. Genotype and phenotype analysis at the 22q11 schizophrenia susceptibility locus. Cold Spring Harbor Symposia On Quantitative Biology. 61: 835-43. PMID 9246508 DOI: 10.1101/Sqb.1996.061.01.082  0.76
1996 Gogos JA, Karayiorgou M. Sequence-specific and length-dependent interaction of C2H2 zinc fingers and (TA)n microsatellites. Human Genetics. 98: 616-9. PMID 8882885 DOI: 10.1007/S004390050269  0.642
1990 Gogos JA, Karayiorgou M, Aburatani H, Kafatos FC. Detection of single base mismatches of thymine and cytosine residues by potassium permanganate and hydroxylamine in the presence of tetralkylammonium salts. Nucleic Acids Research. 18: 6807-14. PMID 2263445 DOI: 10.1093/nar/18.23.6807  0.646
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