| Year |
Citation |
Score |
| 2024 |
Chang WL, Hen R. Adult Neurogenesis, Context Encoding, and Pattern Separation: A Pathway for Treating Overgeneralization. Advances in Neurobiology. 38: 163-193. PMID 39008016 DOI: 10.1007/978-3-031-62983-9_10 |
0.451 |
|
| 2024 |
Santiago AN, Castello-Saval J, Nguyen P, Chung HM, Luna VM, Hen R, Chang WL. Effects of electroconvulsive shock on the function, circuitry, and transcriptome of dentate gyrus granule neurons. Biorxiv : the Preprint Server For Biology. PMID 38496461 DOI: 10.1101/2024.03.01.583011 |
0.51 |
|
| 2024 |
Chang WL, Tegang K, Samuels BA, Saxe M, Wichmann J, David DJ, David IM, Augustin A, Fischer H, Golling S, Lamerz J, Roth D, Graf M, Zoffmann S, Santarelli L, ... ... Hen R, et al. Pharmacological Enhancement of Adult Hippocampal Neurogenesis Improves Behavioral Pattern Separation in Young and Aged Mice. Biorxiv : the Preprint Server For Biology. PMID 38352378 DOI: 10.1101/2024.02.01.578406 |
0.816 |
|
| 2023 |
Tuncdemir SN, Grosmark AD, Chung H, Luna VM, Lacefield CO, Losonczy A, Hen R. Adult-born granule cells facilitate remapping of spatial and non-spatial representations in the dentate gyrus. Neuron. PMID 37820723 DOI: 10.1016/j.neuron.2023.09.016 |
0.806 |
|
| 2023 |
Lim SC, Fusi S, Hen R. Ventral CA1 Population Codes for Anxiety. Biorxiv : the Preprint Server For Biology. PMID 37808689 DOI: 10.1101/2023.09.25.559358 |
0.687 |
|
| 2023 |
Lacefield C, Cai H, Ho H, Dias C, Chung H, Hen R, Turi GF. An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice. Journal of Visualized Experiments : Jove. PMID 36939265 DOI: 10.3791/64863 |
0.714 |
|
| 2023 |
Tartt AN, Mariani M, Hen R, Mann JJ, Boldrini M. Electroconvulsive therapy-a shocking inducer of neuroplasticity? Molecular Psychiatry. PMID 36869226 DOI: 10.1038/s41380-023-02015-0 |
0.544 |
|
| 2023 |
Paquelet GE, Carrion K, Lacefield CO, Zhou P, Hen R, Miller BR. Protocol for in vivo imaging and analysis of brainstem neuronal activity in the dorsal raphe nucleus of freely behaving mice. Star Protocols. 4: 102074. PMID 36853724 DOI: 10.1016/j.xpro.2023.102074 |
0.782 |
|
| 2022 |
Duque-Quintero M, Hooijmans CR, Hurowitz A, Ahmed A, Barris B, Homberg JR, Hen R, Harris AZ, Balsam P, Atsak P. Enduring effects of early-life adversity on reward processes: A systematic review and meta-analysis of animal studies. Neuroscience and Biobehavioral Reviews. 142: 104849. PMID 36116576 DOI: 10.1016/j.neubiorev.2022.104849 |
0.779 |
|
| 2022 |
Rayan NA, Kumar V, Aow J, Rastegar N, Lim MGL, O'Toole N, Aliwarga E, Arcego DM, Yeo HTG, Wong JY, Lee MY, Schmidt F, Haja HS, Tam WL, Zhang TY, ... ... Hen R, et al. Integrative multi-omics landscape of fluoxetine action across 27 brain regions reveals global increase in energy metabolism and region-specific chromatin remodelling. Molecular Psychiatry. PMID 36056172 DOI: 10.1038/s41380-022-01725-1 |
0.706 |
|
| 2022 |
Carazo-Arias E, Nguyen PT, Kass M, Jee HJ, Nautiyal KM, Magalong V, Coie L, Andreu V, Gergues MM, Khalil H, Akil H, Arcego DM, Meaney M, Anacker C, Samuels BA, ... ... Hen R, et al. Contribution of the Opioid System to the Antidepressant Effects of Fluoxetine. Biological Psychiatry. PMID 35977861 DOI: 10.1016/j.biopsych.2022.05.030 |
0.791 |
|
| 2022 |
Paquelet GE, Carrion K, Lacefield CO, Zhou P, Hen R, Miller BR. Single-cell activity and network properties of dorsal raphe nucleus serotonin neurons during emotionally salient behaviors. Neuron. PMID 35700737 DOI: 10.1016/j.neuron.2022.05.015 |
0.805 |
|
| 2022 |
Tartt AN, Mariani MB, Hen R, Mann JJ, Boldrini M. Dysregulation of adult hippocampal neuroplasticity in major depression: pathogenesis and therapeutic implications. Molecular Psychiatry. PMID 35354926 DOI: 10.1038/s41380-022-01520-y |
0.629 |
|
| 2022 |
Tuncdemir SN, Grosmark AD, Turi GF, Shank A, Bowler JC, Ordek G, Losonczy A, Hen R, Lacefield CO. Parallel processing of sensory cue and spatial information in the dentate gyrus. Cell Reports. 38: 110257. PMID 35045280 DOI: 10.1016/j.celrep.2021.110257 |
0.79 |
|
| 2021 |
Han J, Andreu V, Langreck C, Pekarskaya EA, Grinnell SG, Allain F, Magalong V, Pintar J, Kieffer BL, Harris AZ, Javitch JA, Hen R, Nautiyal KM. Mu opioid receptors on hippocampal GABAergic interneurons are critical for the antidepressant effects of tianeptine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34593976 DOI: 10.1038/s41386-021-01192-2 |
0.805 |
|
| 2021 |
Planchez B, Lagunas N, Le Guisquet AM, Legrand M, Surget A, Hen R, Belzung C. Increasing Adult Hippocampal Neurogenesis Promotes Resilience in a Mouse Model of Depression. Cells. 10. PMID 33919292 DOI: 10.3390/cells10050972 |
0.724 |
|
| 2020 |
Eliwa H, Brizard B, Le Guisquet AM, Hen R, Belzung C, Surget A. Adult neurogenesis augmentation attenuates anhedonia and HPA axis dysregulation in a mouse model of chronic stress and depression. Psychoneuroendocrinology. 124: 105097. PMID 33302237 DOI: 10.1016/j.psyneuen.2020.105097 |
0.732 |
|
| 2020 |
Jimenez JC, Berry JE, Lim SC, Ong SK, Kheirbek MA, Hen R. Contextual fear memory retrieval by correlated ensembles of ventral CA1 neurons. Nature Communications. 11: 3492. PMID 32661319 DOI: 10.1038/S41467-020-17270-W |
0.789 |
|
| 2020 |
Stefanini F, Kushnir L, Jimenez JC, Jennings JH, Woods NI, Stuber GD, Kheirbek MA, Hen R, Fusi S. A Distributed Neural Code in the Dentate Gyrus and in CA1. Neuron. PMID 32521223 DOI: 10.1016/J.Neuron.2020.05.022 |
0.791 |
|
| 2020 |
Tartt A, Arango V, Rosoklija GB, Dwork AJ, Hen R, Mann JJ, Boldrini M. Adult Hippocampal Neurogenesis is Impaired in Untreated Major Depressive Disorder Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.349 |
0.662 |
|
| 2020 |
Tartt A, Rosoklija GB, Fulmore C, Arango V, Dwork AJ, Hen R, Mann JJ, Boldrini M. Dentate Gyrus Immature Neurons in Major Depressive Disorder Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.173 |
0.657 |
|
| 2020 |
Anacker C, Luna V, Shores R, Stevens G, Hen R. Adult Hippocampal Neurogenesis Protects From Chronic Stress Effects in Mice Biological Psychiatry. 87: S58-S59. DOI: 10.1016/J.Biopsych.2020.02.172 |
0.697 |
|
| 2020 |
Mendez-David I, Guilloux J, Shah A, Tritschler L, Defaix C, Fossati P, Colle R, Hen R, Denny C, Gardier A, Corruble E, David D. Serotonin 3 Receptor Blockade is Involved in Vortioxetine -Induced Prevention of Anxiety/Depression Relapse Phenotype Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.1125 |
0.805 |
|
| 2019 |
Faye C, Hen R, Guiard BP, Denny CA, Gardier AM, Mendez-David I, David DJ. Rapid Anxiolytic Effects of RS67333, a Serotonin Type 4 Receptor Agonist, and Diazepam, a Benzodiazepine, Are Mediated by Projections From the Prefrontal Cortex to the Dorsal Raphe Nucleus. Biological Psychiatry. PMID 31623825 DOI: 10.1016/j.biopsych.2019.08.009 |
0.792 |
|
| 2019 |
Tuncdemir SN, Lacefield CO, Hen R. Contributions of adult neurogenesis to dentate gyrus network activity and computations. Behavioural Brain Research. 112112. PMID 31377252 DOI: 10.1016/j.bbr.2019.112112 |
0.802 |
|
| 2019 |
Luna VM, Anacker C, Burghardt NS, Khandaker H, Andreu V, Millette A, Leary P, Ravenelle R, Jimenez JC, Mastrodonato A, Denny CA, Fenton AA, Scharfman HE, Hen R. Adult-born hippocampal neurons bidirectionally modulate entorhinal inputs into the dentate gyrus. Science (New York, N.Y.). 364: 578-583. PMID 31073064 DOI: 10.1126/Science.Aat8789 |
0.795 |
|
| 2019 |
Boldrini M, Galfalvy H, Dwork AJ, Rosoklija GB, Trencevska-Ivanovska I, Pavlovski G, Hen R, Arango V, Mann JJ. Resilience Is Associated With Larger Dentate Gyrus, While Suicide Decedents With Major Depressive Disorder Have Fewer Granule Neurons. Biological Psychiatry. PMID 30819514 DOI: 10.1016/J.Biopsych.2018.12.022 |
0.642 |
|
| 2019 |
Cunningham AM, Santos TL, Gutzeit VA, Hamilton H, Hen R, Donaldson Z. Functional interrogation of a depression-related serotonergic SNP, rs6295, using a humanized mouse model. Acs Chemical Neuroscience. PMID 30694044 DOI: 10.1021/Acschemneuro.8B00638 |
0.697 |
|
| 2019 |
Faye C, Hen R, Guiard B, Denny C, Gardier A, Mendez-David I, David D. Rapid anxiolytic effects of 5-HT4 receptor agonist involves prefrontal cortex-brainstem neural circuit recruitment European Neuropsychopharmacology. 29: S204-S205. DOI: 10.1016/j.euroneuro.2018.11.338 |
0.796 |
|
| 2019 |
Boldrini M, Galfalvy H, Dwork AJ, Rosoklija GB, Hen R, Arango V, Mann JJ. 44. Resilience is Associated With Larger Hippocampal Dentate Gyrus Biological Psychiatry. 85: S18. DOI: 10.1016/J.Biopsych.2019.03.058 |
0.618 |
|
| 2019 |
Anacker C, Luna V, Millette A, Stevens G, Hen R. 42. Inhibiting Ventral Dentate Gyrus Activity Can Prevent Stress-Induced Psychopathology in Mice Biological Psychiatry. 85: S17-S18. DOI: 10.1016/J.Biopsych.2019.03.056 |
0.684 |
|
| 2018 |
Turcotte-Cardin V, Vahid-Ansari F, Luckhart C, Daigle M, Geddes SD, Tanaka KF, Hen R, James J, Merali Z, Béïque JC, Albert PR. Loss of adult 5-HT1A autoreceptors results in a paradoxical anxiogenic response to antidepressant treatment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30552180 DOI: 10.1523/Jneurosci.0352-18.2018 |
0.45 |
|
| 2018 |
Tartt AN, Fulmore CA, Liu Y, Rosoklija GB, Dwork AJ, Arango V, Hen R, Mann JJ, Boldrini M. Considerations for Assessing the Extent of Hippocampal Neurogenesis in the Adult and Aging Human Brain. Cell Stem Cell. 23: 782-783. PMID 30526880 DOI: 10.1016/J.Stem.2018.10.025 |
0.624 |
|
| 2018 |
Anacker C, Luna VM, Stevens GS, Millette A, Shores R, Jimenez JC, Chen B, Hen R. Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus. Nature. PMID 29950730 DOI: 10.1038/S41586-018-0262-4 |
0.813 |
|
| 2018 |
Besnard A, Langberg T, Levinson S, Chu D, Vicidomini C, Scobie KN, Dwork AJ, Arango V, Rosoklija GB, Mann JJ, Hen R, Leonardo ED, Boldrini M, Sahay A. Targeting Kruppel-like Factor 9 in Excitatory Neurons Protects against Chronic Stress-Induced Impairments in Dendritic Spines and Fear Responses. Cell Reports. 23: 3183-3196. PMID 29898391 DOI: 10.1016/J.Celrep.2018.05.040 |
0.805 |
|
| 2018 |
Kempermann G, Gage FH, Aigner L, Song H, Curtis MA, Thuret S, Kuhn HG, Jessberger S, Frankland PW, Cameron HA, Gould E, Hen R, Abrous DN, Toni N, Schinder AF, et al. Human Adult Neurogenesis: Evidence and Remaining Questions. Cell Stem Cell. PMID 29681514 DOI: 10.1016/J.Stem.2018.04.004 |
0.32 |
|
| 2018 |
Pavlova IP, Shipley SC, Lanio M, Hen R, Denny CA. Optimization of immunolabeling and clearing techniques for indelibly-labeled memory traces. Hippocampus. PMID 29663578 DOI: 10.1002/hipo.22951 |
0.77 |
|
| 2018 |
Philippe TJ, Vahid-Ansari F, Donaldson ZR, Le François B, Zahrai A, Turcotte-Cardin V, Daigle M, James J, Hen R, Merali Z, Albert PR. Loss of MeCP2 in adult 5-HT neurons induces 5-HT1A autoreceptors, with opposite sex-dependent anxiety and depression phenotypes. Scientific Reports. 8: 5788. PMID 29636529 DOI: 10.1038/S41598-018-24167-8 |
0.742 |
|
| 2018 |
Boldrini M, Fulmore CA, Tartt AN, Simeon LR, Pavlova I, Poposka V, Rosoklija GB, Stankov A, Arango V, Dwork AJ, Hen R, Mann JJ. Human Hippocampal Neurogenesis Persists throughout Aging. Cell Stem Cell. 22: 589-599.e5. PMID 29625071 DOI: 10.1016/J.Stem.2018.03.015 |
0.792 |
|
| 2018 |
Zhou P, Resendez SL, Rodriguez-Romaguera J, Jimenez JC, Neufeld SQ, Giovannucci A, Friedrich J, Pnevmatikakis EA, Stuber GD, Hen R, Kheirbek MA, Sabatini BL, Kass RE, Paninski L. Efficient and accurate extraction ofcalcium signals from microendoscopic video data. Elife. 7. PMID 29469809 DOI: 10.7554/Elife.28728 |
0.782 |
|
| 2018 |
Jimenez JC, Su K, Goldberg AR, Luna VM, Biane JS, Ordek G, Zhou P, Ong SK, Wright MA, Zweifel L, Paninski L, Hen R, Kheirbek MA. Anxiety Cells in a Hippocampal-Hypothalamic Circuit. Neuron. PMID 29397273 DOI: 10.1016/J.Neuron.2018.01.016 |
0.798 |
|
| 2018 |
Zhou P, Resendez SL, Rodriguez-Romaguera J, Jimenez JC, Neufeld SQ, Giovannucci A, Friedrich J, Pnevmatikakis EA, Stuber GD, Hen R, Kheirbek MA, Sabatini BL, Kass RE, Paninski L. Author response: Efficient and accurate extraction of in vivo calcium signals from microendoscopic video data Elife. DOI: 10.7554/Elife.28728.031 |
0.759 |
|
| 2018 |
Faye C, Mendez-David I, Guiard B, Denny C, Hen R, Gardier A, David D. Rapid anxiolytic effects of a serotonin type 4 receptor agonist involve prefrontal cortex/brainstem neural circuit recruitment European Neuropsychopharmacology. 28: S21-S22. DOI: 10.1016/j.euroneuro.2017.12.040 |
0.821 |
|
| 2018 |
Boldrini M, Simeon-Thompson L, Fulmore C, Tartt A, Dwork AJ, Arango V, Rosoklija GB, Hen R, Mann JJ. S1. Age-Associated Changes in Human Hippocampal Neurogenesis and Angiogenesis Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.892 |
0.599 |
|
| 2018 |
Faye C, Hen R, Guiard B, Denny CA, Gardier A, Mendez-David I, David D. T37. Rapid Anxiolytic Effects of a Serotonin Type 4 Receptor Agonist Involve Prefrontal Cortex-Brainstem Neural Circuit Recruitment Biological Psychiatry. 83: S143. DOI: 10.1016/J.Biopsych.2018.02.373 |
0.788 |
|
| 2018 |
Anacker C, Luna V, Stevens G, Millette A, Shores R, Chen B, Hen R. 190. Neurogenesis Inhibits Stress-Responsive Cells in the Ventral Dentate Gyrus Biological Psychiatry. 83: S76. DOI: 10.1016/J.Biopsych.2018.02.209 |
0.663 |
|
| 2017 |
Tritschler L, Kheirbek MA, Dantec YL, Mendez-David I, Guilloux JP, Faye C, Doan J, Pham TH, Hen R, David DJ, Gardier AM. Optogenetic activation of granule cells in the dorsal dentate gyrus enhances dopaminergic neurotransmission in the Nucleus Accumbens. Neuroscience Research. PMID 29246683 DOI: 10.1016/j.neures.2017.12.002 |
0.781 |
|
| 2017 |
Vahid-Ansari F, Daigle M, Manzini MC, Tanaka KF, Hen R, Geddes SD, Béïque JC, James J, Merali Z, Albert PR. Abrogated Freud-1/CC2D1A repression of 5-HT1A autoreceptors induces fluoxetine-resistant anxiety/depression-like behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29101244 DOI: 10.1523/Jneurosci.1668-17.2017 |
0.317 |
|
| 2017 |
Harris AZ, Atsak P, Bretton ZH, Holt ES, Alam R, Morton MP, Abbas AI, Leonardo ED, Bolkan SS, Hen R, Gordon JA. A Novel Method for Chronic Social Defeat Stress in Female Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29090682 DOI: 10.1038/Npp.2017.259 |
0.782 |
|
| 2017 |
Culig L, Surget A, Bourdey M, Khemissi W, Le Guisquet AM, Vogel E, Sahay A, Hen R, Belzung C. Increasing adult hippocampal neurogenesis in mice after exposure to unpredictable chronic mild stress may counteract some of the effects of stress. Neuropharmacology. PMID 28890366 DOI: 10.1016/J.Neuropharm.2017.09.009 |
0.81 |
|
| 2017 |
Akil H, Gordon J, Hen R, Javitch J, Mayberg H, McEwen B, Meaney MJ, Nestler EJ. Treatment Resistant Depression: A Multi-Scale, Systems Biology Approach. Neuroscience and Biobehavioral Reviews. PMID 28859997 DOI: 10.1016/J.Neubiorev.2017.08.019 |
0.658 |
|
| 2017 |
Nautiyal KM, Okuda M, Hen R, Blanco C. Gambling disorder: an integrative review of animal and human studies. Annals of the New York Academy of Sciences. 1394: 106-127. PMID 28486792 DOI: 10.1111/Nyas.13356 |
0.745 |
|
| 2017 |
Anacker C, Hen R. Adult hippocampal neurogenesis and cognitive flexibility - linking memory and mood. Nature Reviews. Neuroscience. PMID 28469276 DOI: 10.1038/Nrn.2017.45 |
0.696 |
|
| 2017 |
Chen WV, Nwakeze CL, Denny CA, O'Keeffe S, Rieger MA, Mountoufaris G, Kirner A, Dougherty JD, Hen R, Wu Q, Maniatis T. Pcdhαc2 is required for axonal tiling and assembly of serotonergic circuitries in mice. Science (New York, N.Y.). 356: 406-411. PMID 28450636 DOI: 10.1126/Science.Aal3231 |
0.776 |
|
| 2017 |
Samuels BA, Nautiyal KM, Kruegel AC, Levinstein MR, Magalong VM, Gassaway MM, Grinnell SG, Han J, Ansonoff MA, Pintar JE, Javitch JA, Sames D, Hen R. The Behavioral Effects of the Antidepressant Tianeptine Require the Mu Opioid Receptor. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28303899 DOI: 10.1038/Npp.2017.60 |
0.801 |
|
| 2017 |
Nautiyal KM, Hen R. Serotonin receptors in depression: from A to B. F1000research. 6: 123. PMID 28232871 DOI: 10.12688/F1000Research.9736.1 |
0.784 |
|
| 2017 |
Guilloux JP, Samuels BA, Mendez-David I, Hu A, Levinstein M, Faye C, Mekiri M, Mocaer E, Gardier AM, Hen R, Sors A, David DJ. S 38093, a histamine H3 antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice. Scientific Reports. 7: 42946. PMID 28218311 DOI: 10.1038/Srep42946 |
0.803 |
|
| 2017 |
Anacker C, Luna V, Millette A, Hen R. Adult hippocampal neurogenesis determines vulnerability and resilience to stress-induced psychiatric disorders European Neuropsychopharmacology. 27: S561. DOI: 10.1016/S0924-977X(17)31078-7 |
0.678 |
|
| 2017 |
Anacker C, Luna V, Millette A, Hen R. 696. Adult Hippocampal Neurogenesis Promotes Stress Resilience by Inhibiting Ventral Dentate Gyrus Activity Biological Psychiatry. 81: S282. DOI: 10.1016/J.Biopsych.2017.02.763 |
0.677 |
|
| 2016 |
Nautiyal KM, Wall MM, Wang S, Magalong VM, Ahmari SE, Balsam PD, Blanco C, Hen R. Genetic and Modelling Approaches Reveal Distinct Components of Impulsive Behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27976680 DOI: 10.1038/Npp.2016.277 |
0.801 |
|
| 2016 |
McAvoy KM, Scobie KN, Berger S, Russo C, Guo N, Decharatanachart P, Vega-Ramirez H, Miake-Lye S, Whalen M, Nelson M, Bergami M, Bartsch D, Hen R, Berninger B, Sahay A. Modulating Neuronal Competition Dynamics in the Dentate Gyrus to Rejuvenate Aging Memory Circuits. Neuron. 91: 1356-73. PMID 27593178 DOI: 10.1016/J.Neuron.2016.08.009 |
0.795 |
|
| 2016 |
Nautiyal KM, Tritschler L, Ahmari SE, David DJ, Gardier AM, Hen R. A Lack of Serotonin 1B Autoreceptors Results in Decreased Anxiety and Depression-Related Behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 41: 2941-2950. PMID 27353308 DOI: 10.1038/Npp.2016.109 |
0.827 |
|
| 2016 |
Tannenholz L, Hen R, Kheirbek MA. GluN2B-Containg NMDA Receptors on Adult-Born Granule Cells Contribute to the Antidepressant Action of Fluoxetine. Frontiers in Neuroscience. 10: 242. PMID 27303260 DOI: 10.3389/fnins.2016.00242 |
0.82 |
|
| 2016 |
Danielson NB, Kaifosh P, Zaremba JD, Lovett-Barron M, Tsai J, Denny CA, Balough EM, Goldberg AR, Drew LJ, Hen R, Losonczy A, Kheirbek MA. Distinct Contribution of Adult-Born Hippocampal Granule Cells to Context Encoding. Neuron. 90: 101-12. PMID 26971949 DOI: 10.1016/J.Neuron.2016.02.019 |
0.804 |
|
| 2016 |
Donaldson ZR, le Francois B, Santos TL, Almli LM, Boldrini M, Champagne FA, Arango V, Mann JJ, Stockmeier CA, Galfalvy H, Albert PR, Ressler KJ, Hen R. The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription. Translational Psychiatry. 6: e746. PMID 26926882 DOI: 10.1038/Tp.2015.226 |
0.788 |
|
| 2016 |
Drew LJ, Kheirbek MA, Luna VM, Denny CA, Cloidt MA, Wu MV, Jain S, Scharfman HE, Hen R. Activation of local inhibitory circuits in the dentate gyrus by adult-born neurons. Hippocampus. 26: 763-78. PMID 26662922 DOI: 10.1002/Hipo.22557 |
0.806 |
|
| 2016 |
Anacker C, Scholz J, O'Donnell KJ, Allemang-Grand R, Diorio J, Bagot RC, Nestler EJ, Hen R, Lerch JP, Meaney MJ. Neuroanatomic Differences Associated With Stress Susceptibility and Resilience. Biological Psychiatry. 79: 840-9. PMID 26422005 DOI: 10.1016/J.Biopsych.2015.08.009 |
0.696 |
|
| 2016 |
Apkarian AV, Mutso AA, Centeno MV, Kan L, Wu M, Levinstein M, Banisadr G, Gobeske KT, Miller RJ, Radulovic J, Hen R, Kessler JA. Role of adult hippocampal neurogenesis in persistent pain. Pain. 157: 418-28. PMID 26313405 DOI: 10.1097/J.Pain.0000000000000332 |
0.78 |
|
| 2016 |
Brachman RA, McGowan JC, Perusini JN, Lim SC, Pham TH, Faye C, Gardier AM, Mendez-David I, David DJ, Hen R, Denny CA. Ketamine as a Prophylactic Against Stress-Induced Depressive-like Behavior. Biological Psychiatry. 79: 776-86. PMID 26037911 DOI: 10.1016/J.Biopsych.2015.04.022 |
0.775 |
|
| 2016 |
Samuels BA, Mendez-David I, Faye C, David SA, Pierz KA, Gardier AM, Hen R, David DJ. Serotonin 1A and Serotonin 4 Receptors: Essential Mediators of the Neurogenic and Behavioral Actions of Antidepressants. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 22: 26-45. PMID 25488850 DOI: 10.1177/1073858414561303 |
0.725 |
|
| 2016 |
Moriya Y, Hagino Y, Hall SF, Hen R, Ikeda K, Kasahara Y, Sora I, Uhl GR. PM309. Methamphetamine induced changes of monoamine neurotransmission in 5-HT1B KO mice. The International Journal of Neuropsychopharmacology. 19: 10-10. DOI: 10.1093/Ijnp/Pyw041.309 |
0.318 |
|
| 2016 |
Donaldson Z, Hen R, Gutzeit V, Santos TL, Sadsad M, Denny CA. 25.2 SOCIAL BUFFERING OF CONDITIONED AND INNATE FEAR RESPONSES Journal of the American Academy of Child & Adolescent Psychiatry. 55: S297. DOI: 10.1016/J.Jaac.2016.07.262 |
0.767 |
|
| 2015 |
Anacker C, Denny CA, Hen R. Regulation of hippocampal memory traces by neurogenesis. Neurogenesis (Austin, Tex.). 2: e1025180. PMID 27604158 DOI: 10.1080/23262133.2015.1025180 |
0.793 |
|
| 2015 |
Mingote S, Masson J, Gellman C, Thomsen GM, Lin CS, Merker RJ, Gaisler-Salomon I, Wang Y, Ernst R, Hen R, Rayport S. Genetic Pharmacotherapy as an Early CNS Drug Development Strategy: Testing Glutaminase Inhibition for Schizophrenia Treatment in Adult Mice. Frontiers in Systems Neuroscience. 9: 165. PMID 26778975 DOI: 10.3389/Fnsys.2015.00165 |
0.353 |
|
| 2015 |
Samuels BA, Anacker C, Hu A, Levinstein MR, Pickenhagen A, Tsetsenis T, Madroñal N, Donaldson ZR, Drew LJ, Dranovsky A, Gross CT, Tanaka KF, Hen R. 5-HT1A receptors on mature dentate gyrus granule cells are critical for the antidepressant response. Nature Neuroscience. 18: 1606-16. PMID 26389840 DOI: 10.1038/Nn.4116 |
0.821 |
|
| 2015 |
Borgkvist A, Avegno EM, Wong MY, Kheirbek MA, Sonders MS, Hen R, Sulzer D. Loss of Striatonigral GABAergic Presynaptic Inhibition Enables Motor Sensitization in Parkinsonian Mice. Neuron. 87: 976-88. PMID 26335644 DOI: 10.1016/J.Neuron.2015.08.022 |
0.795 |
|
| 2015 |
Wu MV, Luna VM, Hen R. Running rescues a fear-based contextual discrimination deficit in aged mice. Frontiers in Systems Neuroscience. 9: 114. PMID 26321926 DOI: 10.3389/Fnsys.2015.00114 |
0.354 |
|
| 2015 |
Park EH, Burghardt NS, Dvorak D, Hen R, Fenton AA. Experience-Dependent Regulation of Dentate Gyrus Excitability by Adult-Born Granule Cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11656-66. PMID 26290242 DOI: 10.1523/Jneurosci.0885-15.2015 |
0.398 |
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| 2015 |
Wu MV, Sahay A, Duman RS, Hen R. Functional differentiation of adult-born neurons along the septotemporal axis of the dentate gyrus. Cold Spring Harbor Perspectives in Biology. 7: a018978. PMID 26238355 DOI: 10.1101/Cshperspect.A018978 |
0.619 |
|
| 2015 |
Nautiyal KM, Tanaka KF, Barr MM, Tritschler L, Le Dantec Y, David DJ, Gardier AM, Blanco C, Hen R, Ahmari SE. Distinct Circuits Underlie the Effects of 5-HT1B Receptors on Aggression and Impulsivity. Neuron. 86: 813-26. PMID 25892302 DOI: 10.1016/J.Neuron.2015.03.041 |
0.817 |
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| 2015 |
Hill AS, Sahay A, Hen R. Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 2368-78. PMID 25833129 DOI: 10.1038/Npp.2015.85 |
0.828 |
|
| 2015 |
Samuels BA, Leonardo ED, Hen R. Hippocampal subfields and major depressive disorder. Biological Psychiatry. 77: 210-1. PMID 25542516 DOI: 10.1016/j.biopsych.2014.11.007 |
0.703 |
|
| 2015 |
Iyengar SS, LaFrancois JJ, Friedman D, Drew LJ, Denny CA, Burghardt NS, Wu MV, Hsieh J, Hen R, Scharfman HE. Suppression of adult neurogenesis increases the acute effects of kainic acid. Experimental Neurology. 264: 135-49. PMID 25476494 DOI: 10.1016/J.Expneurol.2014.11.009 |
0.785 |
|
| 2015 |
Miller BR, Hen R. The current state of the neurogenic theory of depression and anxiety. Current Opinion in Neurobiology. 30: 51-8. PMID 25240202 DOI: 10.1016/j.conb.2014.08.012 |
0.359 |
|
| 2015 |
Donaldson ZR, Hen R. From psychiatric disorders to animal models: a bidirectional and dimensional approach. Biological Psychiatry. 77: 15-21. PMID 24650688 DOI: 10.1016/J.Biopsych.2014.02.004 |
0.68 |
|
| 2015 |
Borgkvist A, Avegno EM, Wong MY, Kheirbek MA, Sonders MS, Hen R, Sulzer D. Loss of Striatonigral GABAergic Presynaptic Inhibition Enables Motor Sensitization in Parkinsonian Mice Neuron. 87: 976-988. DOI: 10.1016/j.neuron.2015.08.022 |
0.767 |
|
| 2015 |
Mendez-David I, David DJ, Guilloux JP, Hen R, Gardier AM. 5-ht4 receptor subtype, β-arrestin level, and rapid-onset effects of antidepressant drugs Neuromethods. 95: 101-121. DOI: 10.1007/978-1-4939-2187-4_6 |
0.61 |
|
| 2014 |
Hall FS, Sora I, Hen R, Uhl GR. Serotonin/dopamine interactions in a hyperactive mouse: reduced serotonin receptor 1B activity reverses effects of dopamine transporter knockout. Plos One. 9: e115009. PMID 25514162 DOI: 10.1371/journal.pone.0115009 |
0.37 |
|
| 2014 |
Root CM, Denny CA, Hen R, Axel R. The participation of cortical amygdala in innate, odour-driven behaviour. Nature. 515: 269-73. PMID 25383519 DOI: 10.1038/nature13897 |
0.787 |
|
| 2014 |
Denny CA, Kheirbek MA, Alba EL, Tanaka KF, Brachman RA, Laughman KB, Tomm NK, Turi GF, Losonczy A, Hen R. Hippocampal memory traces are differentially modulated by experience, time, and adult neurogenesis. Neuron. 83: 189-201. PMID 24991962 DOI: 10.1016/J.Neuron.2014.05.018 |
0.777 |
|
| 2014 |
Kheirbek MA, Hen R. Add neurons, subtract anxiety. Scientific American. 311: 62-7. PMID 24974712 DOI: 10.1038/Scientificamerican0714-62 |
0.792 |
|
| 2014 |
Boldrini M, Butt TH, Santiago AN, Tamir H, Dwork AJ, Rosoklija GB, Arango V, Hen R, Mann JJ. Benzodiazepines and the potential trophic effect of antidepressants on dentate gyrus cells in mood disorders. The International Journal of Neuropsychopharmacology. 17: 1923-33. PMID 24969726 DOI: 10.1017/S1461145714000844 |
0.664 |
|
| 2014 |
Lovett-Barron M, Kaifosh P, Kheirbek MA, Danielson N, Zaremba JD, Reardon TR, Turi GF, Hen R, Zemelman BV, Losonczy A. Dendritic inhibition in the hippocampus supports fear learning. Science (New York, N.Y.). 343: 857-63. PMID 24558155 DOI: 10.1126/Science.1247485 |
0.795 |
|
| 2014 |
Wu MV, Hen R. Functional dissociation of adult-born neurons along the dorsoventral axis of the dentate gyrus. Hippocampus. 24: 751-61. PMID 24550158 DOI: 10.1002/hipo.22265 |
0.422 |
|
| 2014 |
Wu MV, Shamy JL, Bedi G, Choi CW, Wall MM, Arango V, Boldrini M, Foltin RW, Hen R. Impact of social status and antidepressant treatment on neurogenesis in the baboon hippocampus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1861-71. PMID 24518288 DOI: 10.1038/Npp.2014.33 |
0.685 |
|
| 2014 |
Samuels BA, Leonardo ED, Dranovsky A, Williams A, Wong E, Nesbitt AM, McCurdy RD, Hen R, Alter M. Global state measures of the dentate gyrus gene expression system predict antidepressant-sensitive behaviors. Plos One. 9: e85136. PMID 24465494 DOI: 10.1371/Journal.Pone.0085136 |
0.686 |
|
| 2014 |
Mendez-David I, David DJ, Darcet F, Wu MV, Kerdine-Römer S, Gardier AM, Hen R. Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1366-78. PMID 24287720 DOI: 10.1038/Npp.2013.332 |
0.422 |
|
| 2014 |
Donaldson ZR, Piel DA, Santos TL, Richardson-Jones J, Leonardo ED, Beck SG, Champagne FA, Hen R. Developmental effects of serotonin 1A autoreceptors on anxiety and social behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 291-302. PMID 23907404 DOI: 10.1038/Npp.2013.185 |
0.818 |
|
| 2014 |
Brachman RA, McGowan JC, Perusini JN, Lim SC, Pham TH, Faye C, Gardier AM, Mendez-David I, David DJ, Hen R, Denny CA. Ketamine as a Prophylactic Against Stress-Induced Depressive-Like Behavior Biological Psychiatry. DOI: 10.1016/j.biopsych.2015.04.022 |
0.79 |
|
| 2013 |
Ikrar T, Guo N, He K, Besnard A, Levinson S, Hill A, Lee HK, Hen R, Xu X, Sahay A. Adult neurogenesis modifies excitability of the dentate gyrus. Frontiers in Neural Circuits. 7: 204. PMID 24421758 DOI: 10.3389/Fncir.2013.00204 |
0.807 |
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| 2013 |
Drew LJ, Fusi S, Hen R. Adult neurogenesis in the mammalian hippocampus: why the dentate gyrus? Learning & Memory (Cold Spring Harbor, N.Y.). 20: 710-29. PMID 24255101 DOI: 10.1101/lm.026542.112 |
0.596 |
|
| 2013 |
Mendez-David I, El-Ali Z, Hen R, Falissard B, Corruble E, Gardier AM, Kerdine-Römer S, David DJ. A method for biomarker measurements in peripheral blood mononuclear cells isolated from anxious and depressed mice: β-arrestin 1 protein levels in depression and treatment. Frontiers in Pharmacology. 4: 124. PMID 24133448 DOI: 10.3389/fphar.2013.00124 |
0.309 |
|
| 2013 |
Kheirbek MA, Hen R. (Radio)active neurogenesis in the human hippocampus. Cell. 153: 1183-4. PMID 23746833 DOI: 10.1016/j.cell.2013.05.033 |
0.79 |
|
| 2013 |
Ahmari SE, Spellman T, Douglass NL, Kheirbek MA, Simpson HB, Deisseroth K, Gordon JA, Hen R. Repeated cortico-striatal stimulation generates persistent OCD-like behavior. Science (New York, N.Y.). 340: 1234-9. PMID 23744948 DOI: 10.1126/Science.1234733 |
0.792 |
|
| 2013 |
Guilloux JP, Mendez-David I, Pehrson A, Guiard BP, Repérant C, Orvoën S, Gardier AM, Hen R, Ebert B, Miller S, Sanchez C, David DJ. Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice. Neuropharmacology. 73: 147-59. PMID 23721744 DOI: 10.1016/J.Neuropharm.2013.05.014 |
0.811 |
|
| 2013 |
Stott SR, Metzakopian E, Lin W, Kaestner KH, Hen R, Ang SL. Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 8022-34. PMID 23637192 DOI: 10.1523/Jneurosci.4774-12.2013 |
0.336 |
|
| 2013 |
Quesseveur G, David DJ, Gaillard MC, Pla P, Wu MV, Nguyen HT, Nicolas V, Auregan G, David I, Dranovsky A, Hantraye P, Hen R, Gardier AM, Déglon N, Guiard BP. BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. Translational Psychiatry. 3: e253. PMID 23632457 DOI: 10.1038/Tp.2013.30 |
0.393 |
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| 2013 |
Mendez-David I, Hen R, Gardier AM, David DJ. Adult hippocampal neurogenesis: an actor in the antidepressant-like action. Annales Pharmaceutiques Francaises. 71: 143-9. PMID 23622692 DOI: 10.1016/j.pharma.2013.02.006 |
0.394 |
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| 2013 |
Kheirbek MA, Drew LJ, Burghardt NS, Costantini DO, Tannenholz L, Ahmari SE, Zeng H, Fenton AA, Hen R. Differential control of learning and anxiety along the dorsoventral axis of the dentate gyrus. Neuron. 77: 955-68. PMID 23473324 DOI: 10.1016/J.Neuron.2012.12.038 |
0.797 |
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| 2013 |
Donaldson ZR, Nautiyal KM, Ahmari SE, Hen R. Genetic approaches for understanding the role of serotonin receptors in mood and behavior. Current Opinion in Neurobiology. 23: 399-406. PMID 23385115 DOI: 10.1016/J.Conb.2013.01.011 |
0.807 |
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| 2013 |
Castrén E, Hen R. Neuronal plasticity and antidepressant actions. Trends in Neurosciences. 36: 259-67. PMID 23380665 DOI: 10.1016/j.tins.2012.12.010 |
0.361 |
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| 2013 |
Boldrini M, Santiago AN, Hen R, Dwork AJ, Rosoklija GB, Tamir H, Arango V, John Mann J. Hippocampal granule neuron number and dentate gyrus volume in antidepressant-treated and untreated major depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1068-77. PMID 23303074 DOI: 10.1038/Npp.2013.5 |
0.636 |
|
| 2013 |
Jang MH, Kitabatake Y, Kang E, Jun H, Pletnikov MV, Christian KM, Hen R, Lucae S, Binder EB, Song H, Ming GI. Secreted frizzled-related protein 3 (sFRP3) regulates antidepressant responses in mice and humans. Molecular Psychiatry. 18: 957-8. PMID 23207650 DOI: 10.1038/Mp.2012.158 |
0.312 |
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| 2013 |
Profirovic J, Strekalova E, Urao N, Krbanjevic A, Andreeva AV, Varadarajan S, Fukai T, Hen R, Ushio-Fukai M, Voyno-Yasenetskaya TA. A novel regulator of angiogenesis in endothelial cells: 5-hydroxytriptamine 4 receptor. Angiogenesis. 16: 15-28. PMID 22903372 DOI: 10.1007/s10456-012-9296-7 |
0.321 |
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| 2012 |
Kheirbek MA, Klemenhagen KC, Sahay A, Hen R. Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders. Nature Neuroscience. 15: 1613-20. PMID 23187693 DOI: 10.1038/Nn.3262 |
0.804 |
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| 2012 |
Fava M, Targum SD, Nierenberg AA, Bleicher LS, Carter TA, Wedel PC, Hen R, Gage FH, Barlow C. An exploratory study of combination buspirone and melatonin SR in major depressive disorder (MDD): a possible role for neurogenesis in drug discovery. Journal of Psychiatric Research. 46: 1553-63. PMID 22998742 DOI: 10.1016/J.Jpsychires.2012.08.013 |
0.329 |
|
| 2012 |
Baudouin SJ, Gaudias J, Gerharz S, Hatstatt L, Zhou K, Punnakkal P, Tanaka KF, Spooren W, Hen R, De Zeeuw CI, Vogt K, Scheiffele P. Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism. Science (New York, N.Y.). 338: 128-32. PMID 22983708 DOI: 10.1126/Science.1224159 |
0.311 |
|
| 2012 |
Tanaka KF, Matsui K, Sasaki T, Sano H, Sugio S, Fan K, Hen R, Nakai J, Yanagawa Y, Hasuwa H, Okabe M, Deisseroth K, Ikenaka K, Yamanaka A. Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system. Cell Reports. 2: 397-406. PMID 22854021 DOI: 10.1016/J.Celrep.2012.06.011 |
0.525 |
|
| 2012 |
Tanaka KF, Samuels BA, Hen R. Serotonin receptor expression along the dorsal-ventral axis of mouse hippocampus. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 2395-401. PMID 22826340 DOI: 10.1098/rstb.2012.0038 |
0.722 |
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| 2012 |
Kheirbek MA, Tannenholz L, Hen R. NR2B-dependent plasticity of adult-born granule cells is necessary for context discrimination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8696-702. PMID 22723709 DOI: 10.1523/JNEUROSCI.1692-12.2012 |
0.814 |
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| 2012 |
Boldrini M, Hen R, Underwood MD, Rosoklija GB, Dwork AJ, Mann JJ, Arango V. Hippocampal angiogenesis and progenitor cell proliferation are increased with antidepressant use in major depression. Biological Psychiatry. 72: 562-71. PMID 22652019 DOI: 10.1016/J.Biopsych.2012.04.024 |
0.661 |
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| 2012 |
Glinka ME, Samuels BA, Diodato A, Teillon J, Feng Mei D, Shykind BM, Hen R, Fleischmann A. Olfactory deficits cause anxiety-like behaviors in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6718-25. PMID 22573694 DOI: 10.1523/JNEUROSCI.4287-11.2012 |
0.807 |
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| 2012 |
Burghardt NS, Park EH, Hen R, Fenton AA. Adult-born hippocampal neurons promote cognitive flexibility in mice. Hippocampus. 22: 1795-808. PMID 22431384 DOI: 10.1002/Hipo.22013 |
0.376 |
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| 2012 |
Gire DH, Franks KM, Zak JD, Tanaka KF, Whitesell JD, Mulligan AA, Hen R, Schoppa NE. Mitral cells in the olfactory bulb are mainly excited through a multistep signaling path. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2964-75. PMID 22378870 DOI: 10.1523/Jneurosci.5580-11.2012 |
0.542 |
|
| 2012 |
Denny CA, Burghardt NS, Schachter DM, Hen R, Drew MR. 4- to 6-week-old adult-born hippocampal neurons influence novelty-evoked exploration and contextual fear conditioning. Hippocampus. 22: 1188-201. PMID 21739523 DOI: 10.1002/Hipo.20964 |
0.813 |
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| 2012 |
Rainer Q, Xia L, Guilloux JP, Gabriel C, Mocaër E, Hen R, Enhamre E, Gardier AM, David DJ. Beneficial behavioural and neurogenic effects of agomelatine in a model of depression/anxiety. The International Journal of Neuropsychopharmacology. 15: 321-35. PMID 21473810 DOI: 10.1017/S1461145711000356 |
0.827 |
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| 2012 |
Lacefield CO, Itskov V, Reardon T, Hen R, Gordon JA. Effects of adult-generated granule cells on coordinated network activity in the dentate gyrus. Hippocampus. 22: 106-16. PMID 20882540 DOI: 10.1002/Hipo.20860 |
0.81 |
|
| 2011 |
Karpova NN, Pickenhagen A, Lindholm J, Tiraboschi E, Kulesskaya N, Agústsdóttir A, Antila H, Popova D, Akamine Y, Bahi A, Sullivan R, Hen R, Drew LJ, Castrén E. Fear erasure in mice requires synergy between antidepressant drugs and extinction training. Science (New York, N.Y.). 334: 1731-4. PMID 22194582 DOI: 10.1126/science.1214592 |
0.39 |
|
| 2011 |
Dranovsky A, Picchini AM, Moadel T, Sisti AC, Yamada A, Kimura S, Leonardo ED, Hen R. Experience dictates stem cell fate in the adult hippocampus. Neuron. 70: 908-23. PMID 21658584 DOI: 10.1016/J.Neuron.2011.05.022 |
0.32 |
|
| 2011 |
Sahay A, Wilson DA, Hen R. Pattern separation: a common function for new neurons in hippocampus and olfactory bulb. Neuron. 70: 582-8. PMID 21609817 DOI: 10.1016/J.Neuron.2011.05.012 |
0.585 |
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| 2011 |
Surget A, Tanti A, Leonardo ED, Laugeray A, Rainer Q, Touma C, Palme R, Griebel G, Ibarguen-Vargas Y, Hen R, Belzung C. Antidepressants recruit new neurons to improve stress response regulation. Molecular Psychiatry. 16: 1177-88. PMID 21537331 DOI: 10.1038/Mp.2011.48 |
0.816 |
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| 2011 |
Richardson-Jones JW, Craige CP, Nguyen TH, Kung HF, Gardier AM, Dranovsky A, David DJ, Guiard BP, Beck SG, Hen R, Leonardo ED. Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6008-18. PMID 21508226 DOI: 10.1523/JNEUROSCI.5836-10.2011 |
0.805 |
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| 2011 |
Sahay A, Scobie KN, Hill AS, O'Carroll CM, Kheirbek MA, Burghardt NS, Fenton AA, Dranovsky A, Hen R. Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation. Nature. 472: 466-70. PMID 21460835 DOI: 10.1038/Nature09817 |
0.802 |
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| 2011 |
Samuels BA, Hen R. Neurogenesis and affective disorders. The European Journal of Neuroscience. 33: 1152-9. PMID 21395859 DOI: 10.1111/j.1460-9568.2011.07614.x |
0.722 |
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| 2011 |
Samuels BA, Leonardo ED, Gadient R, Williams A, Zhou J, David DJ, Gardier AM, Wong EH, Hen R. Modeling treatment-resistant depression. Neuropharmacology. 61: 408-13. PMID 21356220 DOI: 10.1016/j.neuropharm.2011.02.017 |
0.681 |
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| 2011 |
Guilloux JP, David DJ, Xia L, Nguyen HT, Rainer Q, Guiard BP, Repérant C, Deltheil T, Toth M, Hen R, Gardier AM. Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments. Neuropharmacology. 61: 478-88. PMID 21333660 DOI: 10.1016/J.Neuropharm.2011.02.009 |
0.809 |
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| 2011 |
Weber T, Baier V, Pauly R, Sahay A, Baur M, Herrmann E, Ciccolini F, Hen R, Kronenberg G, Bartsch D. Inducible gene expression in GFAP+ progenitor cells of the SGZ and the dorsal wall of the SVZ-A novel tool to manipulate and trace adult neurogenesis. Glia. 59: 615-26. PMID 21294160 DOI: 10.1002/Glia.21129 |
0.567 |
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| 2011 |
Chuhma N, Tanaka KF, Hen R, Rayport S. Functional connectome of the striatal medium spiny neuron. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1183-92. PMID 21273403 DOI: 10.1523/JNEUROSCI.3833-10.2011 |
0.307 |
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| 2011 |
Yadav VK, Oury F, Tanaka KF, Tanaka K, Thomas T, Wang Y, Cremers S, Hen R, Krust A, Chambon P, Karsenty G. Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications. The Journal of Experimental Medicine. 208: 41-52. PMID 21187319 DOI: 10.1084/Jem.20101940 |
0.376 |
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| 2011 |
Kheirbek MA, Hen R. Dorsal vs ventral hippocampal neurogenesis: implications for cognition and mood. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 373-4. PMID 21116266 DOI: 10.1038/npp.2010.148 |
0.812 |
|
| 2011 |
Samuels BA, Hen R. Novelty-suppressed feeding in the mouse Neuromethods. 63: 107-121. DOI: 10.1007/978-1-61779-313-4_7 |
0.627 |
|
| 2010 |
David DJ, Wang J, Samuels BA, Rainer Q, David I, Gardier AM, Hen R. Implications of the functional integration of adult-born hippocampal neurons in anxiety-depression disorders. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 16: 578-91. PMID 20889967 DOI: 10.1177/1073858409360281 |
0.818 |
|
| 2010 |
Drew MR, Denny CA, Hen R. Arrest of adult hippocampal neurogenesis in mice impairs single- but not multiple-trial contextual fear conditioning. Behavioral Neuroscience. 124: 446-54. PMID 20695644 DOI: 10.1037/A0020081 |
0.803 |
|
| 2010 |
Segu L, Lecomte MJ, Wolff M, Santamaria J, Hen R, Dumuis A, Berrard S, Bockaert J, Buhot MC, Compan V. Hyperfunction of muscarinic receptor maintains long-term memory in 5-HT4 receptor knock-out mice. Plos One. 5: e9529. PMID 20209108 DOI: 10.1371/Journal.Pone.0009529 |
0.688 |
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| 2010 |
Crupi R, Cambiaghi M, Spatz L, Hen R, Thorn M, Friedman E, Vita G, Battaglia F. Reduced adult neurogenesis and altered emotional behaviors in autoimmune-prone B-cell activating factor transgenic mice. Biological Psychiatry. 67: 558-66. PMID 20185032 DOI: 10.1016/J.Biopsych.2009.12.008 |
0.337 |
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| 2010 |
Tanaka KF, Ahmari SE, Leonardo ED, Richardson-Jones JW, Budreck EC, Scheiffele P, Sugio S, Inamura N, Ikenaka K, Hen R. Flexible Accelerated STOP Tetracycline Operator-knockin (FAST): a versatile and efficient new gene modulating system. Biological Psychiatry. 67: 770-3. PMID 20163789 DOI: 10.1016/J.Biopsych.2009.12.020 |
0.79 |
|
| 2010 |
Richardson-Jones JW, Craige CP, Guiard BP, Stephen A, Metzger KL, Kung HF, Gardier AM, Dranovsky A, David DJ, Beck SG, Hen R, Leonardo ED. 5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants. Neuron. 65: 40-52. PMID 20152112 DOI: 10.1016/J.Neuron.2009.12.003 |
0.801 |
|
| 2010 |
Richardson-Jones JW, Leonardo ED, Hen R, Ahmari SE. Animal models of anxiety disorders: Behavioral and genetic approaches Anxiety Disorders: Theory, Research, and Clinical Perspectives. 156-167. DOI: 10.1017/CBO9780511777578.016 |
0.788 |
|
| 2010 |
Rainer Q, Gabriel C, Mocaer E, Xia L, Hen R, Enhamre E, Guilloux J, Gardier A, David D. P01-74 - Beneficial effects of chronic treatment with agomelatine on the anxiety-and depression-like state induced by corticosterone in C57BL/6NTAC mice European Psychiatry. 25: 295. DOI: 10.1016/S0924-9338(10)70293-5 |
0.822 |
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| 2010 |
Ahmari SE, Alter MD, Hen R. Aversive Emotions: Genetic Mechanisms of Serotonin Encyclopedia of Neuroscience. 1039-1045. DOI: 10.1016/B978-008045046-9.00834-2 |
0.596 |
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| 2009 |
Rainer Q, Gardier AM, Hen R, David DJ. [Neurogenesis-dependent and independent effects of anti-depressant drugs]. Medecine Sciences : M/S. 25: 795-8. PMID 19849978 DOI: 10.1051/Medsci/20092510795 |
0.707 |
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| 2009 |
Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C, Klemenhagen KC, Tanaka KF, Gingrich JA, Guo XE, Tecott LH, Mann JJ, Hen R, Horvath TL, Karsenty G. A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell. 138: 976-89. PMID 19737523 DOI: 10.1016/J.Cell.2009.06.051 |
0.791 |
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| 2009 |
Scobie KN, Hall BJ, Wilke SA, Klemenhagen KC, Fujii-Kuriyama Y, Ghosh A, Hen R, Sahay A. Krüppel-like factor 9 is necessary for late-phase neuronal maturation in the developing dentate gyrus and during adult hippocampal neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9875-87. PMID 19657039 DOI: 10.1523/Jneurosci.2260-09.2009 |
0.813 |
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| 2009 |
Liu MT, Kuan YH, Wang J, Hen R, Gershon MD. 5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9683-99. PMID 19657021 DOI: 10.1523/Jneurosci.1145-09.2009 |
0.605 |
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| 2009 |
Boldrini M, Underwood MD, Hen R, Rosoklija GB, Dwork AJ, John Mann J, Arango V. Antidepressants increase neural progenitor cells in the human hippocampus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2376-89. PMID 19606083 DOI: 10.1038/Npp.2009.75 |
0.631 |
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| 2009 |
Alter MD, Gilani AI, Champagne FA, Curley JP, Turner JB, Hen R. Paternal transmission of complex phenotypes in inbred mice. Biological Psychiatry. 66: 1061-6. PMID 19577226 DOI: 10.1016/J.Biopsych.2009.05.026 |
0.529 |
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| 2009 |
Gaisler-Salomon I, Miller GM, Chuhma N, Lee S, Zhang H, Ghoddoussi F, Lewandowski N, Fairhurst S, Wang Y, Conjard-Duplany A, Masson J, Balsam P, Hen R, Arancio O, Galloway MP, et al. Glutaminase-deficient mice display hippocampal hypoactivity, insensitivity to pro-psychotic drugs and potentiated latent inhibition: relevance to schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2305-22. PMID 19516252 DOI: 10.1038/Npp.2009.58 |
0.608 |
|
| 2009 |
David DJ, Samuels BA, Rainer Q, Wang JW, Marsteller D, Mendez I, Drew M, Craig DA, Guiard BP, Guilloux JP, Artymyshyn RP, Gardier AM, Gerald C, Antonijevic IA, Leonardo ED, ... Hen R, et al. Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron. 62: 479-93. PMID 19477151 DOI: 10.1016/J.Neuron.2009.04.017 |
0.817 |
|
| 2009 |
Deltheil T, Tanaka K, Reperant C, Hen R, David DJ, Gardier AM. Synergistic neurochemical and behavioural effects of acute intrahippocampal injection of brain-derived neurotrophic factor and antidepressants in adult mice. The International Journal of Neuropsychopharmacology. 12: 905-15. PMID 19236729 DOI: 10.1017/S1461145709000017 |
0.401 |
|
| 2009 |
Moulin-Sallanon M, Charnay Y, Ginovart N, Perret P, Lanfumey L, Hamon M, Hen R, Fagret D, Ibáñez V, Millet P. Acute and chronic effects of citalopram on 5-HT1A receptor-labeling by [18F]MPPF and -coupling to receptors-G proteins. Synapse (New York, N.Y.). 63: 106-16. PMID 19016488 DOI: 10.1002/syn.20588 |
0.347 |
|
| 2009 |
Shanahan NA, Holick Pierz KA, Masten VL, Waeber C, Ansorge M, Gingrich JA, Geyer MA, Hen R, Dulawa SC. Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice. Biological Psychiatry. 65: 401-8. PMID 19013555 DOI: 10.1016/J.Biopsych.2008.09.026 |
0.401 |
|
| 2009 |
Liu M, Wang J, Hen R, Gershon MD. T1665 5-HT4-Stimulated Neuroprotection and Neurogenesis in the Enteric Nervous System (ENS): Significance in Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice Gastroenterology. 136: A-553. DOI: 10.1016/S0016-5085(09)62545-2 |
0.501 |
|
| 2008 |
Alter MD, Hen R. Putting a KAP on transcription and stress. Neuron. 60: 733-5. PMID 19081366 DOI: 10.1016/j.neuron.2008.12.002 |
0.333 |
|
| 2008 |
Deltheil T, Guiard BP, Cerdan J, David DJ, Tanaka KF, Repérant C, Guilloux JP, Coudoré F, Hen R, Gardier AM. Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice. Neuropharmacology. 55: 1006-14. PMID 18761360 DOI: 10.1016/j.neuropharm.2008.08.001 |
0.712 |
|
| 2008 |
Sahay A, Hen R. Hippocampal neurogenesis and depression. Novartis Foundation Symposium. 289: 152-60; discussion 1. PMID 18497101 DOI: 10.1002/9780470751251.Ch12 |
0.628 |
|
| 2008 |
Ase AR, Reader TA, Hen R, Descarries L. Regionally selective changes in neurotransmitter receptors in the brain of the 5-HT1B knockout mouse. Journal of Chemical Neuroanatomy. 35: 356-63. PMID 18406571 DOI: 10.1016/J.Jchemneu.2008.02.007 |
0.324 |
|
| 2008 |
Surget A, Saxe M, Leman S, Ibarguen-Vargas Y, Chalon S, Griebel G, Hen R, Belzung C. Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal. Biological Psychiatry. 64: 293-301. PMID 18406399 DOI: 10.1016/J.Biopsych.2008.02.022 |
0.803 |
|
| 2008 |
Wang JW, Dranovsky A, Hen R. The when and where of BDNF and the antidepressant response. Biological Psychiatry. 63: 640-1. PMID 18329441 DOI: 10.1016/j.biopsych.2008.01.008 |
0.578 |
|
| 2008 |
Wang JW, David DJ, Monckton JE, Battaglia F, Hen R. Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1374-84. PMID 18256257 DOI: 10.1523/JNEUROSCI.3632-07.2008 |
0.576 |
|
| 2008 |
Leonardo ED, Hen R. Anxiety as a developmental disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 134-40. PMID 17851538 DOI: 10.1038/Sj.Npp.1301569 |
0.32 |
|
| 2008 |
Guiard BP, David DJ, Deltheil T, Chenu F, Le Maître E, Renoir T, Leroux-Nicollet I, Sokoloff P, Lanfumey L, Hamon M, Andrews AM, Hen R, Gardier AM. Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype. The International Journal of Neuropsychopharmacology. 11: 79-92. PMID 17559709 DOI: 10.1017/S1461145707007857 |
0.389 |
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| 2008 |
Holick KA, Lee DC, Hen R, Dulawa SC. Behavioral effects of chronic fluoxetine in BALB/cJ mice do not require adult hippocampal neurogenesis or the serotonin 1A receptor. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 406-17. PMID 17429410 DOI: 10.1038/Sj.Npp.1301399 |
0.833 |
|
| 2008 |
Sahay A, Hen R, Duman RS. 23 Hippocampal Neurogenesis: Depression and Antidepressant Responses Cold Spring Harbor Monograph Archive. 52: 483-501. DOI: 10.1101/087969784.52.483 |
0.617 |
|
| 2008 |
Liu M, Kuan Y, Wang J, Hen R, Gershon MD. 649 5-HT4 Stimulation Promotes the Generation of New Neurons and Enhances Neuronal Survival in the Enteric Nervous System (ENS) of Adult Mice Gastroenterology. 134: A-94. DOI: 10.1016/S0016-5085(08)60440-0 |
0.53 |
|
| 2008 |
Chao M, Flint J, Giedd JN, Malaspina D, Hen R, Spedding M, Owen MJ, Sklar P, Akil H, Buonanno A. General discussion II Novartis Foundation Symposium. 289: 193-195. |
0.553 |
|
| 2007 |
Jean A, Conductier G, Manrique C, Bouras C, Berta P, Hen R, Charnay Y, Bockaert J, Compan V. Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. 104: 16335-40. PMID 17913892 DOI: 10.1073/Pnas.0701471104 |
0.792 |
|
| 2007 |
Sahay A, Drew MR, Hen R. Dentate gyrus neurogenesis and depression. Progress in Brain Research. 163: 697-722. PMID 17765746 DOI: 10.1016/S0079-6123(07)63038-6 |
0.743 |
|
| 2007 |
Sahay A, Hen R. Adult hippocampal neurogenesis in depression. Nature Neuroscience. 10: 1110-5. PMID 17726477 DOI: 10.1038/Nn1969 |
0.612 |
|
| 2007 |
Drew MR, Hen R. Adult hippocampal neurogenesis as target for the treatment of depression. Cns & Neurological Disorders Drug Targets. 6: 205-18. PMID 17511617 DOI: 10.2174/187152707780619353 |
0.668 |
|
| 2007 |
Perera TD, Coplan JD, Lisanby SH, Lipira CM, Arif M, Carpio C, Spitzer G, Santarelli L, Scharf B, Hen R, Rosoklija G, Sackeim HA, Dwork AJ. Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4894-901. PMID 17475797 DOI: 10.1523/Jneurosci.0237-07.2007 |
0.423 |
|
| 2007 |
Sibille E, Su J, Leman S, Le Guisquet AM, Ibarguen-Vargas Y, Joeyen-Waldorf J, Glorioso C, Tseng GC, Pezzone M, Hen R, Belzung C. Lack of serotonin1B receptor expression leads to age-related motor dysfunction, early onset of brain molecular aging and reduced longevity. Molecular Psychiatry. 12: 1042-56, 975. PMID 17420766 DOI: 10.1038/sj.mp.4001990 |
0.692 |
|
| 2007 |
Pereira AC, Huddleston DE, Brickman AM, Sosunov AA, Hen R, McKhann GM, Sloan R, Gage FH, Brown TR, Small SA. An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus. Proceedings of the National Academy of Sciences of the United States of America. 104: 5638-43. PMID 17374720 DOI: 10.1073/Pnas.0611721104 |
0.302 |
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| 2007 |
Saxe MD, Malleret G, Vronskaya S, Mendez I, Garcia AD, Sofroniew MV, Kandel ER, Hen R. Paradoxical influence of hippocampal neurogenesis on working memory. Proceedings of the National Academy of Sciences of the United States of America. 104: 4642-6. PMID 17360577 DOI: 10.1073/Pnas.0611718104 |
0.787 |
|
| 2007 |
Sanders AC, Hussain AJ, Hen R, Zhuang X. Chronic blockade or constitutive deletion of the serotonin transporter reduces operant responding for food reward. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2321-9. PMID 17356573 DOI: 10.1038/Sj.Npp.1301368 |
0.746 |
|
| 2007 |
David DJ, Klemenhagen KC, Holick KA, Saxe MD, Mendez I, Santarelli L, Craig DA, Zhong H, Swanson CJ, Hegde LG, Ping XI, Dong D, Marzabadi MR, Gerald CP, Hen R. Efficacy of the MCHR1 antagonist N-[3-(1-{[4-(3,4-difluorophenoxy)phenyl]methyl}(4-piperidyl))-4-methylphenyl]-2-methylpropanamide (SNAP 94847) in mouse models of anxiety and depression following acute and chronic administration is independent of hippocampal neurogenesis. The Journal of Pharmacology and Experimental Therapeutics. 321: 237-48. PMID 17237257 DOI: 10.1124/Jpet.106.109678 |
0.8 |
|
| 2007 |
Scharfman HE, Hen R. Neuroscience. Is more neurogenesis always better? Science (New York, N.Y.). 315: 336-8. PMID 17234934 DOI: 10.1126/science.1138711 |
0.312 |
|
| 2007 |
Stark KL, Gross C, Richardson-Jones J, Zhuang X, Hen R. A novel conditional knockout strategy applied to serotonin receptors. Handbook of Experimental Pharmacology. 347-63. PMID 17203662 DOI: 10.1007/978-3-540-35109-2_14 |
0.809 |
|
| 2007 |
Ansorge MS, Hen R, Gingrich JA. Neurodevelopmental origins of depressive disorders. Current Opinion in Pharmacology. 7: 8-17. PMID 17188022 DOI: 10.1016/j.coph.2006.11.006 |
0.321 |
|
| 2007 |
Gobbi G, Cassano T, Radja F, Morgese MG, Cuomo V, Santarelli L, Hen R, Blier P. Neurokinin 1 receptor antagonism requires norepinephrine to increase serotonin function. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 17: 328-38. PMID 16950604 DOI: 10.1016/J.Euroneuro.2006.07.004 |
0.39 |
|
| 2007 |
Sibille E, Su J, Leman S, Le Guisquet AM, Ibarguen-Vargas Y, Joeyen-Waldorf J, Glorioso C, Tseng GC, Pezzone M, Hen R, Belzung C. Upregulated sirtuin 5 gene expression in frontal cortex of serotonin 1b receptor knock out mice Molecular Psychiatry. 12: 975. DOI: 10.1038/sj.mp.4002115 |
0.687 |
|
| 2006 |
Saxe MD, Battaglia F, Wang JW, Malleret G, David DJ, Monckton JE, Garcia AD, Sofroniew MV, Kandel ER, Santarelli L, Hen R, Drew MR. Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus. Proceedings of the National Academy of Sciences of the United States of America. 103: 17501-6. PMID 17088541 DOI: 10.1073/Pnas.0607207103 |
0.81 |
|
| 2006 |
Gordon JA, Hen R. TREKing toward new antidepressants. Nature Neuroscience. 9: 1081-3. PMID 16936765 DOI: 10.1038/nn0906-1081 |
0.611 |
|
| 2006 |
Conductier G, Dusticier N, Lucas G, Côté F, Debonnel G, Daszuta A, Dumuis A, Nieoullon A, Hen R, Bockaert J, Compan V. Adaptive changes in serotonin neurons of the raphe nuclei in 5-HT(4) receptor knock-out mouse. The European Journal of Neuroscience. 24: 1053-62. PMID 16930432 DOI: 10.1111/J.1460-9568.2006.04943.X |
0.801 |
|
| 2006 |
Weisstaub NV, Zhou M, Lira A, Lambe E, González-Maeso J, Hornung JP, Sibille E, Underwood M, Itohara S, Dauer WT, Ansorge MS, Morelli E, Mann JJ, Toth M, Aghajanian G, ... ... Hen R, et al. Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice. Science (New York, N.Y.). 313: 536-40. PMID 16873667 DOI: 10.1126/Science.1123432 |
0.807 |
|
| 2006 |
Dranovsky A, Hen R. Hippocampal neurogenesis: regulation by stress and antidepressants. Biological Psychiatry. 59: 1136-43. PMID 16797263 DOI: 10.1016/j.biopsych.2006.03.082 |
0.42 |
|
| 2006 |
Meshi D, Drew MR, Saxe M, Ansorge MS, David D, Santarelli L, Malapani C, Moore H, Hen R. Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment. Nature Neuroscience. 9: 729-31. PMID 16648847 DOI: 10.1038/Nn1696 |
0.814 |
|
| 2006 |
Masson J, Darmon M, Conjard A, Chuhma N, Ropert N, Thoby-Brisson M, Foutz AS, Parrot S, Miller GM, Jorisch R, Polan J, Hamon M, Hen R, Rayport S. Mice lacking brain/kidney phosphate-activated glutaminase have impaired glutamatergic synaptic transmission, altered breathing, disorganized goal-directed behavior and die shortly after birth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4660-71. PMID 16641247 DOI: 10.1523/Jneurosci.4241-05.2006 |
0.328 |
|
| 2006 |
Leonardo ED, Hen R. Genetics of affective and anxiety disorders. Annual Review of Psychology. 57: 117-37. PMID 16318591 DOI: 10.1146/annurev.psych.57.102904.190118 |
0.306 |
|
| 2006 |
Leonardo ED, Richardson-Jones JW, Sibille E, Kottman A, Hen R. Molecular heterogeneity along the dorsal-ventral axis of the murine hippocampal CA1 field: a microarray analysis of gene expression. Neuroscience. 137: 177-86. PMID 16309847 DOI: 10.1016/j.neuroscience.2005.08.082 |
0.778 |
|
| 2006 |
Klemenhagen KC, Gordon JA, David DJ, Hen R, Gross CT. Increased fear response to contextual cues in mice lacking the 5-HT1A receptor. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 101-11. PMID 15920501 DOI: 10.1038/Sj.Npp.1300774 |
0.816 |
|
| 2005 |
Gordon JA, Lacefield CO, Kentros CG, Hen R. State-dependent alterations in hippocampal oscillations in serotonin 1A receptor-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6509-19. PMID 16014712 DOI: 10.1523/JNEUROSCI.1211-05.2005 |
0.811 |
|
| 2005 |
Dulawa SC, Hen R. Recent advances in animal models of chronic antidepressant effects: the novelty-induced hypophagia test. Neuroscience and Biobehavioral Reviews. 29: 771-83. PMID 15890403 DOI: 10.1016/j.neubiorev.2005.03.017 |
0.328 |
|
| 2005 |
Zhuang X, Masson J, Gingrich JA, Rayport S, Hen R. Targeted gene expression in dopamine and serotonin neurons of the mouse brain. Journal of Neuroscience Methods. 143: 27-32. PMID 15763133 DOI: 10.1016/j.jneumeth.2004.09.020 |
0.761 |
|
| 2005 |
Doetsch F, Hen R. Young and excitable: the function of new neurons in the adult mammalian brain. Current Opinion in Neurobiology. 15: 121-8. PMID 15721754 DOI: 10.1016/j.conb.2005.01.018 |
0.354 |
|
| 2005 |
Conductier G, Crosson C, Hen R, Bockaert J, Compan V. 3,4-N-methlenedioxymethamphetamine-induced hypophagia is maintained in 5-HT1B receptor knockout mice, but suppressed by the 5-HT2C receptor antagonist RS102221. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1056-63. PMID 15668722 DOI: 10.1038/Sj.Npp.1300662 |
0.812 |
|
| 2005 |
Surget A, Saxe M, Griebel G, Chalon S, Leman S, Hen R, Belzung C. A74 HIPPOCAMPAL NEUROGENESIS CONTRIBUTES TO THE EFFICACY OF IMIPRAMINE AND CRF1 ANTAGONIST (SSR125543A) FOLLOWING A CHRONIC UNPREDICTABLE STRESS PROCEDURE IN MICE Behavioural Pharmacology. 16: S46. DOI: 10.1097/00008877-200509001-00146 |
0.799 |
|
| 2004 |
Gross C, Hen R. Genetic and environmental factors interact to influence anxiety. Neurotoxicity Research. 6: 493-501. PMID 15639782 DOI: 10.1007/Bf03033286 |
0.65 |
|
| 2004 |
Etkin A, Klemenhagen KC, Dudman JT, Rogan MT, Hen R, Kandel ER, Hirsch J. Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces. Neuron. 44: 1043-55. PMID 15603746 DOI: 10.1016/J.Neuron.2004.12.006 |
0.789 |
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| 2004 |
Wolff M, Costet P, Gross C, Hen R, Segu L, Buhot MC. Age-dependent effects of serotonin-1A receptor gene deletion in spatial learning abilities in mice. Brain Research. Molecular Brain Research. 130: 39-48. PMID 15519675 DOI: 10.1016/J.Molbrainres.2004.07.012 |
0.683 |
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| 2004 |
Ansorge MS, Zhou M, Lira A, Hen R, Gingrich JA. Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science (New York, N.Y.). 306: 879-81. PMID 15514160 DOI: 10.1126/science.1101678 |
0.423 |
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| 2004 |
El-Khodor BF, Dimmler MH, Amara DA, Hofer M, Hen R, Brunner D. Juvenile 5HT(1B) receptor knockout mice exhibit reduced pharmacological sensitivity to 5HT(1A) receptor activation. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 22: 405-13. PMID 15380839 DOI: 10.1016/J.Ijdevneu.2004.06.001 |
0.366 |
|
| 2004 |
Gordon JA, Hen R. Genetic approaches to the study of anxiety. Annual Review of Neuroscience. 27: 193-222. PMID 15217331 DOI: 10.1146/annurev.neuro.27.070203.144212 |
0.609 |
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| 2004 |
Gross C, Hen R. The developmental origins of anxiety. Nature Reviews. Neuroscience. 5: 545-52. PMID 15208696 DOI: 10.1038/nrn1429 |
0.632 |
|
| 2004 |
Compan V, Charnay Y, Dusticier N, Daszuta A, Hen R, Bockaert J. [Feeding disorders in 5-HT4 receptor knockout mice]. Journal De La Societe De Biologie. 198: 37-49. PMID 15146954 |
0.674 |
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| 2004 |
Mannoury la Cour C, Hanoun N, Melfort M, Hen R, Lesch KP, Hamon M, Lanfumey L. GABA(B) receptors in 5-HT transporter- and 5-HT1A receptor-knock-out mice: further evidence of a transduction pathway shared with 5-HT1A receptors. Journal of Neurochemistry. 89: 886-96. PMID 15140188 DOI: 10.1111/j.1471-4159.2004.02367.x |
0.372 |
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| 2004 |
Dulawa SC, Holick KA, Gundersen B, Hen R. Effects of chronic fluoxetine in animal models of anxiety and depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1321-30. PMID 15085085 DOI: 10.1038/Sj.Npp.1300433 |
0.794 |
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| 2004 |
Rumajogee P, Vergé D, Hanoun N, Brisorgueil MJ, Hen R, Lesch KP, Hamon M, Miquel MC. Adaption of the serotoninergic neuronal phenotype in the absence of 5-HT autoreceptors or the 5-HT transporter: involvement of BDNF and cAMP. The European Journal of Neuroscience. 19: 937-44. PMID 15009141 DOI: 10.1111/j.0953-816X.2004.03194.x |
0.363 |
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| 2004 |
Gordon JA, Hen R. The serotonergic system and anxiety. Neuromolecular Medicine. 5: 27-40. PMID 15001810 DOI: 10.1385/NMM:5:1:027 |
0.663 |
|
| 2004 |
Chuhma N, Zhang H, Masson J, Zhuang X, Sulzer D, Hen R, Rayport S. Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 972-81. PMID 14749442 DOI: 10.1523/JNEUROSCI.4317-03.2004 |
0.732 |
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| 2004 |
Compan V, Zhou M, Grailhe R, Gazzara RA, Martin R, Gingrich J, Dumuis A, Brunner D, Bockaert J, Hen R. Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 412-9. PMID 14724239 DOI: 10.1523/Jneurosci.2806-03.2004 |
0.71 |
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| 2004 |
Compan V, Charnay Y, Dusticier N, Daszuta A, Hen R, Boekaert J. Anomalies de la prise alimentaire chez la souris dépourvue de récepteur 5-HT4 Journal De La SociéTé De Biologie. 198: 37-49. DOI: 10.1051/Jbio/2004198010037 |
0.605 |
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| 2003 |
Buhot MC, Wolff M, Benhassine N, Costet P, Hen R, Segu L. Spatial learning in the 5-HT1B receptor knockout mouse: selective facilitation/impairment depending on the cognitive demand. Learning & Memory (Cold Spring Harbor, N.Y.). 10: 466-77. PMID 14657258 DOI: 10.1101/Lm.60203 |
0.352 |
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| 2003 |
Lira A, Zhou M, Castanon N, Ansorge MS, Gordon JA, Francis JH, Bradley-Moore M, Lira J, Underwood MD, Arango V, Kung HF, Hofer MA, Hen R, Gingrich JA. Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice. Biological Psychiatry. 54: 960-71. PMID 14625138 DOI: 10.1016/S0006-3223(03)00696-6 |
0.662 |
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| 2003 |
Wolff M, Benhassine N, Costet P, Hen R, Segu L, Buhot MC. Delay-dependent working memory impairment in young-adult and aged 5-HT1BKO mice as assessed in a radial-arm water maze. Learning & Memory (Cold Spring Harbor, N.Y.). 10: 401-9. PMID 14557613 DOI: 10.1101/Lm.60103 |
0.379 |
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| 2003 |
González-Maeso J, Yuen T, Ebersole BJ, Wurmbach E, Lira A, Zhou M, Weisstaub N, Hen R, Gingrich JA, Sealfon SC. Transcriptome fingerprints distinguish hallucinogenic and nonhallucinogenic 5-hydroxytryptamine 2A receptor agonist effects in mouse somatosensory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8836-43. PMID 14523084 |
0.721 |
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| 2003 |
Santarelli L, Saxe M, Gross C, Surget A, Battaglia F, Dulawa S, Weisstaub N, Lee J, Duman R, Arancio O, Belzung C, Hen R. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science (New York, N.Y.). 301: 805-9. PMID 12907793 DOI: 10.1126/Science.1083328 |
0.825 |
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| 2003 |
Compan V, Scearce-Levie K, Crosson C, Daszuta A, Hen R. Enkephalin contributes to the locomotor stimulating effects of 3,4-methylenedioxy-N-methylamphetamine. The European Journal of Neuroscience. 18: 383-90. PMID 12887420 DOI: 10.1046/J.1460-9568.2003.02767.X |
0.788 |
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| 2003 |
Gardier AM, David DJ, Jego G, Przybylski C, Jacquot C, Durier S, Gruwez B, Douvier E, Beauverie P, Poisson N, Hen R, Bourin M. Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice. Journal of Neurochemistry. 86: 13-24. PMID 12807420 DOI: 10.1046/J.1471-4159.2003.01827.X |
0.398 |
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| 2003 |
Buhot MC, Wolff M, Savova M, Malleret G, Hen R, Segu L. Protective effect of 5-HT1B receptor gene deletion on the age-related decline in spatial learning abilities in mice. Behavioural Brain Research. 142: 135-42. PMID 12798274 DOI: 10.1016/S0166-4328(02)00400-X |
0.348 |
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| 2003 |
Monaca C, Boutrel B, Hen R, Hamon M, Adrien J. 5-HT 1A/1B receptor-mediated effects of the selective serotonin reuptake inhibitor, citalopram, on sleep: studies in 5-HT 1A and 5-HT 1B knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 850-6. PMID 12637954 DOI: 10.1038/Sj.Npp.1300109 |
0.336 |
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| 2003 |
Ralph-Williams RJ, Paulus MP, Zhuang X, Hen R, Geyer MA. Valproate attenuates hyperactive and perseverative behaviors in mutant mice with a dysregulated dopamine system. Biological Psychiatry. 53: 352-9. PMID 12586455 DOI: 10.1016/S0006-3223(02)01489-0 |
0.749 |
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| 2003 |
Wolff M, Savova M, Malleret G, Hen R, Segu L, Buhot MC. Serotonin 1B knockout mice exhibit a task-dependent selective learning facilitation. Neuroscience Letters. 338: 1-4. PMID 12565126 DOI: 10.1016/S0304-3940(02)01339-3 |
0.333 |
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| 2003 |
Weller A, Leguisamo AC, Towns L, Ramboz S, Bagiella E, Hofer M, Hen R, Brunner D. Maternal effects in infant and adult phenotypes of 5HT1A and 5HT1B receptor knockout mice. Developmental Psychobiology. 42: 194-205. PMID 12555283 DOI: 10.1002/Dev.10079 |
0.35 |
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| 2003 |
Wahlsten D, Metten P, Phillips TJ, Boehm SL, Burkhart-Kasch S, Dorow J, Doerksen S, Downing C, Fogarty J, Rodd-Henricks K, Hen R, McKinnon CS, Merrill CM, Nolte C, Schalomon M, et al. Different data from different labs: lessons from studies of gene-environment interaction. Journal of Neurobiology. 54: 283-311. PMID 12486710 DOI: 10.1002/Neu.10173 |
0.323 |
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| 2003 |
Fiorica-Howells E, Liu M, Ponimaskin EG, Li Z, Compan V, Hen R, Gingrich JA, Gershon MD. Distribution of 5-Ht4 receptors in wild-type mice and analyses of intestinal motility in 5-Ht4 knockout mice Gastroenterology. 124: A342. DOI: 10.1016/S0016-5085(03)81723-7 |
0.679 |
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| 2002 |
Santarelli L, Gobbi G, Blier P, Hen R. Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1). The Journal of Clinical Psychiatry. 63: 11-7. PMID 12562138 |
0.322 |
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| 2002 |
Nestler EJ, Gould E, Manji H, Buncan M, Duman RS, Greshenfeld HK, Hen R, Koester S, Lederhendler I, Meaney M, Robbins T, Winsky L, Zalcman S. Preclinical models: status of basic research in depression. Biological Psychiatry. 52: 503-28. PMID 12361666 DOI: 10.1016/S0006-3223(02)01405-1 |
0.406 |
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| 2002 |
Rodríguez-Manzo G, López-Rubalcava C, Hen R, Fernández-Guasti A. Participation of 5-HT(1B) receptors in the inhibitory actions of serotonin on masculine sexual behaviour of mice: pharmacological analysis in 5-HT(1B) receptor knockout mice. British Journal of Pharmacology. 136: 1127-34. PMID 12163345 DOI: 10.1038/sj.bjp.0704827 |
0.358 |
|
| 2002 |
Ase AR, Sénécal J, Reader TA, Hen R, Descarries L. Decreased G-protein coupling of serotonin 5-HT(1A) receptors in the brain of 5-HT(1B) knockout mouse. Neuropharmacology. 42: 941-9. PMID 12069904 DOI: 10.1016/S0028-3908(02)00045-X |
0.338 |
|
| 2002 |
Bonaventure P, Nepomuceno D, Kwok A, Chai W, Langlois X, Hen R, Stark K, Carruthers N, Lovenberg TW. Reconsideration of 5-hydroxytryptamine (5-HT)(7) receptor distribution using [(3)H]5-carboxamidotryptamine and [(3)H]8-hydroxy-2-(di-n-propylamino)tetraline: analysis in brain of 5-HT(1A) knockout and 5-HT(1A/1B) double-knockout mice. The Journal of Pharmacology and Experimental Therapeutics. 302: 240-8. PMID 12065723 DOI: 10.1124/Jpet.302.1.240 |
0.671 |
|
| 2002 |
Malagié I, David DJ, Jolliet P, Hen R, Bourin M, Gardier AM. Improved efficacy of fluoxetine in increasing hippocampal 5-hydroxytryptamine outflow in 5-HT(1B) receptor knock-out mice. European Journal of Pharmacology. 443: 99-104. PMID 12044798 DOI: 10.1016/S0014-2999(02)01604-7 |
0.374 |
|
| 2002 |
Boutrel B, Monaca C, Hen R, Hamon M, Adrien J. Involvement of 5-HT1A receptors in homeostatic and stress-induced adaptive regulations of paradoxical sleep: studies in 5-HT1A knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4686-92. PMID 12040075 DOI: 10.1523/Jneurosci.22-11-04686.2002 |
0.328 |
|
| 2002 |
Upton AL, Ravary A, Salichon N, Moessner R, Lesch KP, Hen R, Seif I, Gaspar P. Lack of 5-HT(1B) receptor and of serotonin transporter have different effects on the segregation of retinal axons in the lateral geniculate nucleus compared to the superior colliculus. Neuroscience. 111: 597-610. PMID 12031347 DOI: 10.1016/S0306-4522(01)00602-9 |
0.329 |
|
| 2002 |
Fiorica-Howells E, Hen R, Gingrich J, Li Z, Gershon MD. 5-HT(2A) receptors: location and functional analysis in intestines of wild-type and 5-HT(2A) knockout mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 282: G877-93. PMID 11960784 DOI: 10.1152/Ajpgi.00435.2001 |
0.322 |
|
| 2002 |
Gross C, Zhuang X, Stark K, Ramboz S, Oosting R, Kirby L, Santarelli L, Beck S, Hen R. Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature. 416: 396-400. PMID 11919622 DOI: 10.1038/416396A |
0.824 |
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| 2002 |
Bouwknecht JA, Hijzen TH, van der Gugten J, Maes RA, Hen R, Olivier B. 5-HT(1B) receptor knockout mice show no adaptive changes in 5-HT(1A) receptor function as measured telemetrically on body temperature and heart rate responses. Brain Research Bulletin. 57: 93-102. PMID 11827741 DOI: 10.1016/S0361-9230(01)00640-2 |
0.354 |
|
| 2002 |
Richer M, Hen R, Blier P. Modification of serotonin neuron properties in mice lacking 5-HT1A receptors. European Journal of Pharmacology. 435: 195-203. PMID 11821026 DOI: 10.1016/S0014-2999(01)01607-7 |
0.404 |
|
| 2001 |
Bouwknecht JA, van der Gugten J, Hijzen TH, Maes RA, Hen R, Olivier B. Male and female 5-HT(1B) receptor knockout mice have higher body weights than wildtypes. Physiology & Behavior. 74: 507-16. PMID 11790410 DOI: 10.1016/S0031-9384(01)00589-3 |
0.335 |
|
| 2001 |
Sibille E, Hen R. Serotonin(1A) receptors in mood disorders: a combined genetic and genomic approach. Behavioural Pharmacology. 12: 429-38. PMID 11742136 |
0.551 |
|
| 2001 |
Yamamoto A, Hen R, Dauer WT. The ons and offs of inducible transgenic technology: a review. Neurobiology of Disease. 8: 923-32. PMID 11741388 DOI: 10.1006/Nbdi.2001.0452 |
0.506 |
|
| 2001 |
Sibille E, Hen R. Combining genetic and genomic approaches to study mood disorders. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 11: 413-21. PMID 11704418 DOI: 10.1016/S0924-977X(01)00118-3 |
0.596 |
|
| 2001 |
Martín-Aparicio E, Yamamoto A, Hernández F, Hen R, Avila J, Lucas JJ. Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 8772-81. PMID 11698589 DOI: 10.1523/Jneurosci.21-22-08772.2001 |
0.544 |
|
| 2001 |
Gardier AM, Gruwez B, Trillat AC, Jacquot C, Hen R, Bourin M. Interaction between 5-HT(1A) and 5-HT(1B) receptors: effects of 8-OH-DPAT-induced hypothermia in 5-HT(1B) receptor knockout mice. European Journal of Pharmacology. 421: 171-5. PMID 11516433 DOI: 10.1016/S0014-2999(01)01037-8 |
0.36 |
|
| 2001 |
Ase AR, Reader TA, Hen R, Riad M, Descarries L. Regional changes in density of serotonin transporter in the brain of 5-HT1A and 5-HT1B knockout mice, and of serotonin innervation in the 5-HT1B knockout. Journal of Neurochemistry. 78: 619-30. PMID 11483665 DOI: 10.1046/J.1471-4159.2001.00437.X |
0.378 |
|
| 2001 |
Gardier AM, Trillat AC, Malagié I, David D, Hascoët M, Colombel MC, Jolliet P, Jacquot C, Hen R, Bourin M. [5-HT1B serotonin receptors and antidepressant effects of selective serotonin reuptake inhibitors ]. Comptes Rendus De L'AcadéMie Des Sciences. SéRie Iii, Sciences De La Vie. 324: 433-41. PMID 11417564 DOI: 10.1016/S0764-4469(01)01332-4 |
0.681 |
|
| 2001 |
Gingrich JA, Hen R. Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice. Psychopharmacology. 155: 1-10. PMID 11374326 DOI: 10.1007/s002130000573 |
0.409 |
|
| 2001 |
Grailhe R, Grabtree GW, Hen R. Human 5-HT(5) receptors: the 5-HT(5A) receptor is functional but the 5-HT(5B) receptor was lost during mammalian evolution. European Journal of Pharmacology. 418: 157-67. PMID 11343685 DOI: 10.1016/S0014-2999(01)00933-5 |
0.312 |
|
| 2001 |
Pattij T, Hijzen TH, Groenink L, Oosting RS, van der Gugten J, Maes RA, Hen R, Olivier B. Stress-induced hyperthermia in the 5-HT(1A) receptor knockout mouse is normal. Biological Psychiatry. 49: 569-74. PMID 11297713 DOI: 10.1016/S0006-3223(00)01022-2 |
0.385 |
|
| 2001 |
Bouwknecht JA, Hijzen TH, van der Gugten J, Maes RA, Hen R, Olivier B. Absence of 5-HT(1B) receptors is associated with impaired impulse control in male 5-HT(1B) knockout mice. Biological Psychiatry. 49: 557-68. PMID 11297712 DOI: 10.1016/S0006-3223(00)01018-0 |
0.387 |
|
| 2001 |
Bouwknecht JA, van der Gugten J, Hijzen TH, Maes RA, Hen R, Olivier B. Corticosterone responses in 5-HT1B receptor knockout mice to stress or 5-HT1A receptor activation are normal. Psychopharmacology. 153: 484-90. PMID 11243496 DOI: 10.1007/S002130000598 |
0.39 |
|
| 2001 |
Zhuang X, Oosting RS, Jones SR, Gainetdinov RR, Miller GW, Caron MG, Hen R. Hyperactivity and impaired response habituation in hyperdopaminergic mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 1982-7. PMID 11172062 DOI: 10.1073/pnas.98.4.1982 |
0.336 |
|
| 2001 |
Santarelli L, Gobbi G, Debs PC, Sibille ET, Blier P, Hen R, Heath MJ. Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function. Proceedings of the National Academy of Sciences of the United States of America. 98: 1912-7. PMID 11172050 DOI: 10.1073/Pnas.98.4.1912 |
0.646 |
|
| 2001 |
Dirks A, Pattij T, Bouwknecht JA, Westphal TT, Hijzen TH, Groenink L, van der Gugten J, Oosting RS, Hen R, Geyer MA, Olivier B. 5-HT1B receptor knockout, but not 5-HT1A receptor knockout mice, show reduced startle reactivity and footshock-induced sensitization, as measured with the acoustic startle response. Behavioural Brain Research. 118: 169-78. PMID 11164514 DOI: 10.1016/S0166-4328(00)00326-0 |
0.397 |
|
| 2001 |
Salichon N, Gaspar P, Upton AL, Picaud S, Hanoun N, Hamon M, Maeyer ED, Murphy DL, Mössner R, Lesch KP, Hen R, Seif I. Excessive activation of serotonin (5-HT) 1B receptors disrupts the formation of sensory maps in monoamine oxidase a and 5-ht transporter knock-out mice. The Journal of Neuroscience. 21: 884-896. DOI: 10.1523/Jneurosci.21-03-00884.2001 |
0.381 |
|
| 2001 |
Gardier A, Trillat A, Malagié I, David D, Hascoët M, Colombel M, Jolliet P, Jacquot C, Hen R, Bourin M. Role of 5-HT1B auto- and heteroreceptors in the mechanism of action of selective serotonin reuptake inhibitors in mice European Neuropsychopharmacology. 11: S208. DOI: 10.1016/S0924-977X(01)80182-6 |
0.641 |
|
| 2000 |
Bouwknecht JA, Hijzen TH, van der Gugten J, Dirks A, Maes RA, Hen R, Geyer MA, Olivier B. Startle responses, heart rate, and temperature in 5-HT1B receptor knockout mice. Neuroreport. 11: 4097-102. PMID 11192635 DOI: 10.1097/00001756-200012180-00037 |
0.333 |
|
| 2000 |
Castanon N, Scearce-Levie K, Lucas JJ, Rocha B, Hen R. Modulation of the effects of cocaine by 5-HT1B receptors: a comparison of knockouts and antagonists. Pharmacology, Biochemistry, and Behavior. 67: 559-66. PMID 11164086 DOI: 10.1016/S0091-3057(00)00389-0 |
0.635 |
|
| 2000 |
Gross C, Santarelli L, Brunner D, Zhuang X, Hen R. Altered fear circuits in 5-HT(1A) receptor KO mice. Biological Psychiatry. 48: 1157-63. PMID 11137057 DOI: 10.1016/S0006-3223(00)01041-6 |
0.78 |
|
| 2000 |
Ase AR, Reader TA, Hen R, Riad M, Descarries L. Altered serotonin and dopamine metabolism in the CNS of serotonin 5-HT(1A) or 5-HT(1B) receptor knockout mice. Journal of Neurochemistry. 75: 2415-26. PMID 11080193 DOI: 10.1046/J.1471-4159.2000.0752415.X |
0.342 |
|
| 2000 |
López-Rubalcava C, Hen R, Cruz SL. Anxiolytic-like actions of toluene in the burying behavior and plus-maze tests: differences in sensitivity between 5-HT(1B) knockout and wild-type mice. Behavioural Brain Research. 115: 85-94. PMID 10996411 DOI: 10.1016/S0166-4328(00)00241-2 |
0.382 |
|
| 2000 |
Bouwknecht JA, Hijzen TH, van der Gugten J, Maes RA, Hen R, Olivier B. Ethanol intake is not elevated in male 5-HT(1B) receptor knockout mice. European Journal of Pharmacology. 403: 95-8. PMID 10969149 DOI: 10.1016/S0014-2999(00)00527-6 |
0.307 |
|
| 2000 |
Zhuang X, Belluscio L, Hen R. G(olf)alpha mediates dopamine D1 receptor signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC91. PMID 10924528 |
0.616 |
|
| 2000 |
Belzung C, Scearce-Levie K, Barreau S, Hen R. Absence of cocaine-induced place conditioning in serotonin 1B receptor knock-out mice. Pharmacology, Biochemistry, and Behavior. 66: 221-5. PMID 10837864 DOI: 10.1016/S0091-3057(00)00238-0 |
0.719 |
|
| 2000 |
Dulawa SC, Scearce-Levie KA, Hen R, Geyer MA. Serotonin releasers increase prepulse inhibition in serotonin 1B knockout mice. Psychopharmacology. 149: 306-12. PMID 10823412 DOI: 10.1007/s002130000373 |
0.671 |
|
| 2000 |
Dulawa SC, Gross C, Stark KL, Hen R, Geyer MA. Knockout mice reveal opposite roles for serotonin 1A and 1B receptors in prepulse inhibition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 650-9. PMID 10788764 DOI: 10.1016/S0893-133X(99)00164-5 |
0.685 |
|
| 2000 |
Yamamoto A, Lucas JJ, Hen R. Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease. Cell. 101: 57-66. PMID 10778856 DOI: 10.1016/S0092-8674(00)80623-6 |
0.526 |
|
| 2000 |
King TE, Heath MJ, Debs P, Davis MB, Hen R, Barr GA. The development of the nociceptive responses in neurokinin-1 receptor knockout mice. Neuroreport. 11: 587-91. PMID 10718319 DOI: 10.1097/00001756-200002280-00031 |
0.324 |
|
| 2000 |
Gingrich JA, Hen R. The broken mouse: the role of development, plasticity and environment in the interpretation of phenotypic changes in knockout mice. Current Opinion in Neurobiology. 10: 146-52. PMID 10679442 DOI: 10.1016/S0959-4388(99)00061-6 |
0.33 |
|
| 2000 |
Sarhan H, Grimaldi B, Hen R, Fillion G. 5-HT1B receptors modulate release of [3H]dopamine from rat striatal synaptosomes: further evidence using 5-HT moduline, polyclonal 5-HT1B receptor antibodies and 5-HT1B receptor knock-out mice. Naunyn-Schmiedeberg's Archives of Pharmacology. 361: 12-8. PMID 10651141 DOI: 10.1007/S002109900163 |
0.342 |
|
| 2000 |
Zhuang X, Belluscio L, Hen R. GOLFα Mediates Dopamine D1 Receptor Signaling The Journal of Neuroscience. 20: RC91-RC91. DOI: 10.1523/JNEUROSCI.20-16-j0001.2000 |
0.771 |
|
| 2000 |
Heath M, Santarelli L, Debs P, Hen R. Room D, 10/17/2000 9: 00 AM - 11: 00 AM (PS) Reduced Anxiety and Stress Responses in Mice Lacking the NK1 Receptor Anesthesiology. 93: A-755. DOI: 10.1097/00000542-200009001-00755 |
0.37 |
|
| 2000 |
Hen R. The use of knockout mice to study the role of 5-HT receptors in animal models of depression European Neuropsychopharmacology. 10: 159. DOI: 10.1016/S0924-977X(00)80062-0 |
0.401 |
|
| 2000 |
Hen R. Animal models of anxiety and depression: from behavior to genomics European Neuropsychopharmacology. 10: 107. DOI: 10.1016/S0924-977X(00)80002-4 |
0.32 |
|
| 2000 |
Battaglla E, Yamamoto A, Girlanda P, Vita G, Toscano A, Hen R, Arancio O. Impaired long-term potentiation in a conditional model of huntington's disease Neurological Sciences. 21: S134-S135. |
0.395 |
|
| 1999 |
Stark KL, Hen R. Knockout Corner. The International Journal of Neuropsychopharmacology. 2: 145-150. PMID 11281982 DOI: 10.1017/S146114579900142X |
0.706 |
|
| 1999 |
Evrard A, Laporte AM, Chastanet M, Hen R, Hamon M, Adrien J. 5-HT1A and 5-HT1B receptors control the firing of serotoninergic neurons in the dorsal raphe nucleus of the mouse: studies in 5-HT1B knock-out mice. The European Journal of Neuroscience. 11: 3823-31. PMID 10583471 DOI: 10.1046/J.1460-9568.1999.00800.X |
0.397 |
|
| 1999 |
Brunner D, Buhot MC, Hen R, Hofer M. Anxiety, motor activation, and maternal-infant interactions in 5HT1B knockout mice. Behavioral Neuroscience. 113: 587-601. PMID 10443785 DOI: 10.1037//0735-7044.113.3.587 |
0.371 |
|
| 1999 |
Zhuang X, Gross C, Santarelli L, Compan V, Trillat AC, Hen R. Altered emotional states in knockout mice lacking 5-HT1A or 5-HT1B receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 21: 52S-60S. PMID 10432489 DOI: 10.1016/S0893-133X(99)00047-0 |
0.83 |
|
| 1999 |
Scearce-Levie K, Chen JP, Gardner E, Hen R. 5-HT receptor knockout mice: pharmacological tools or models of psychiatric disorders. Annals of the New York Academy of Sciences. 868: 701-15. PMID 10414358 DOI: 10.1111/j.1749-6632.1999.tb11350.x |
0.68 |
|
| 1999 |
Malleret G, Hen R, Guillou JL, Segu L, Buhot MC. 5-HT1B receptor knock-out mice exhibit increased exploratory activity and enhanced spatial memory performance in the Morris water maze. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6157-68. PMID 10407051 DOI: 10.1523/Jneurosci.19-14-06157.1999 |
0.416 |
|
| 1999 |
Grailhe R, Waeber C, Dulawa SC, Hornung JP, Zhuang X, Brunner D, Geyer MA, Hen R. Increased exploratory activity and altered response to LSD in mice lacking the 5-HT(5A) receptor. Neuron. 22: 581-91. PMID 10197537 DOI: 10.1016/S0896-6273(00)80712-6 |
0.775 |
|
| 1999 |
Ghavami A, Stark KL, Jareb M, Ramboz S, Ségu L, Hen R. Differential addressing of 5-HT1A and 5-HT1B receptors in epithelial cells and neurons. Journal of Cell Science. 112: 967-76. PMID 10036246 |
0.661 |
|
| 1999 |
Scearce-Levie K, Viswanathan SS, Hen R. Locomotor response to MDMA is attenuated in knockout mice lacking the 5-HT1B receptor. Psychopharmacology. 141: 154-61. PMID 9952039 DOI: 10.1007/s002130050819 |
0.685 |
|
| 1999 |
Stark KL, Hen R. Knockout Corner 5-HT1B receptor knockout mice: A review International Journal of Neuropsychopharmacology. 2: 145-150. |
0.683 |
|
| 1998 |
Trillat AC, Malagié I, Bourin M, Jacquot C, Hen R, Gardier AM. [Homozygote mice deficient in serotonin 5-HT1B receptor and antidepressant effect of selective serotonin reuptake inhibitors]. Comptes Rendus Des SéAnces De La SociéTé De Biologie Et De Ses Filiales. 192: 1139-47. PMID 10101609 |
0.304 |
|
| 1998 |
Dulawa SC, Hen R, Scearce-Levie K, Geyer MA. 5-HT1B receptor modulation of prepulse inhibition: recent findings in wild-type and 5-HT1B knockout mice. Annals of the New York Academy of Sciences. 861: 79-84. PMID 9928242 DOI: 10.1111/j.1749-6632.1998.tb10176.x |
0.671 |
|
| 1998 |
Stark KL, Oosting RS, Hen R. Inducible knockout strategies to probe the functions of 5-HT receptors. Annals of the New York Academy of Sciences. 861: 57-66. PMID 9928239 DOI: 10.1111/J.1749-6632.1998.Tb10173.X |
0.666 |
|
| 1998 |
Ramboz S, Oosting R, Amara DA, Kung HF, Blier P, Mendelsohn M, Mann JJ, Brunner D, Hen R. Serotonin receptor 1A knockout: an animal model of anxiety-related disorder. Proceedings of the National Academy of Sciences of the United States of America. 95: 14476-81. PMID 9826725 DOI: 10.1073/Pnas.95.24.14476 |
0.443 |
|
| 1998 |
Stark KL, Oosting RS, Hen R. Novel strategies to probe the functions of serotonin receptors. Biological Psychiatry. 44: 163-8. PMID 9693388 DOI: 10.1016/S0006-3223(98)00040-7 |
0.66 |
|
| 1998 |
Lucas JJ, Yamamoto A, Scearce-Levie K, Saudou F, Hen R. Absence of fenfluramine-induced anorexia and reduced c-Fos induction in the hypothalamus and central amygdaloid complex of serotonin 1B receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5537-44. PMID 9651234 DOI: 10.1523/Jneurosci.18-14-05537.1998 |
0.798 |
|
| 1998 |
Rocha BA, Scearce-Levie K, Lucas JJ, Hiroi N, Castanon N, Crabbe JC, Nestler EJ, Hen R. Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. Nature. 393: 175-8. PMID 9603521 DOI: 10.1038/30259 |
0.643 |
|
| 1998 |
Oosting RS, Stark KL, Hen R, van Scharrenburg GJM. New animal models in target discovery Pharmacochemistry Library. 29: 203-213. DOI: 10.1016/S0165-7208(98)80058-5 |
0.625 |
|
| 1997 |
Brunner D, Hen R. Insights into the neurobiology of impulsive behavior from serotonin receptor knockout mice. Annals of the New York Academy of Sciences. 836: 81-105. PMID 9616795 DOI: 10.1111/j.1749-6632.1997.tb52356.x |
0.383 |
|
| 1997 |
Ghavami A, Baruscotti M, Robinson RB, Hen R. Adenovirus-mediated expression of 5-HT1B receptors in cardiac ventricle myocytes; coupling to inwardly rectifying K+ channels. European Journal of Pharmacology. 340: 259-66. PMID 9537822 DOI: 10.1016/S0014-2999(97)01404-0 |
0.303 |
|
| 1997 |
Trillat AC, Malagié I, Scearce K, Pons D, Anmella MC, Jacquot C, Hen R, Gardier AM. Regulation of serotonin release in the frontal cortex and ventral hippocampus of homozygous mice lacking 5-HT1B receptors: in vivo microdialysis studies. Journal of Neurochemistry. 69: 2019-25. PMID 9349547 DOI: 10.1046/J.1471-4159.1997.69052019.X |
0.39 |
|
| 1997 |
Dulawa SC, Hen R, Scearce-Levie K, Geyer MA. Serotonin1B receptor modulation of startle reactivity, habituation, and prepulse inhibition in wild-type and serotonin1B knockout mice. Psychopharmacology. 132: 125-34. PMID 9266609 DOI: 10.1007/s002130050328 |
0.666 |
|
| 1997 |
Obosi LA, Hen R, Beadle DJ, Bermudez I, King LA. Mutational analysis of the mouse 5-HT7 receptor: importance of the third intracellular loop for receptor-G-protein interaction. Febs Letters. 412: 321-4. PMID 9256244 DOI: 10.1016/S0014-5793(97)00813-2 |
0.319 |
|
| 1997 |
Lucas JJ, Segu L, Hen R. 5-Hydroxytryptamine1B receptors modulate the effect of cocaine on c-fos expression: converging evidence using 5-hydroxytryptamine1B knockout mice and the 5-hydroxytryptamine1B/1D antagonist GR127935. Molecular Pharmacology. 51: 755-63. PMID 9145913 DOI: 10.1124/Mol.51.5.755 |
0.346 |
|
| 1997 |
Grailhe R, Boschert U, Hen R. The 5-HT5, 5-HT6 and 5-HT7 receptors Pharmacochemistry Library. 27: 311-323. DOI: 10.1016/S0165-7208(97)80018-9 |
0.311 |
|
| 1996 |
Ramboz S, Saudou F, Amara DA, Belzung C, Segu L, Misslin R, Buhot MC, Hen R. 5-HT1B receptor knock out--behavioral consequences. Behavioural Brain Research. 73: 305-12. PMID 8788525 DOI: 10.1016/0166-4328(96)00119-2 |
0.747 |
|
| 1996 |
Ramboz S, Saudou F, Amara DA, Belzung C, Dierich A, LeMeur M, Segu L, Misslin R, Buhot MC, Hen R. Behavioral characterization of mice packing the 5-HT1B receptor. Nida Research Monograph. 161: 39-57. PMID 8784843 |
0.699 |
|
| 1996 |
Crabbe JC, Phillips TJ, Feller DJ, Hen R, Wenger CD, Lessov CN, Schafer GL. Elevated alcohol consumption in null mutant mice lacking 5-HT1B serotonin receptors. Nature Genetics. 14: 98-101. PMID 8782828 DOI: 10.1038/Ng0996-98 |
0.335 |
|
| 1996 |
Piñeyro G, Hen R, Blier P. Multiple 5-HT receptor subtypes regulate [3H]5-HT release in terminal projection areas: Superfusion studies in rat and mice brain European Neuropsychopharmacology. 6: 51. DOI: 10.1016/0924-977X(96)87536-5 |
0.335 |
|
| 1995 |
Piñeyro G, Castanon N, Hen R, Blier P. Regulation of [3H]5-HT release in raphe, frontal cortex and hippocampus of 5-HT1B knock-out mice. Neuroreport. 7: 353-9. PMID 8742487 DOI: 10.1097/00001756-199512000-00084 |
0.345 |
|
| 1995 |
Heath MJ, Hen R. Serotonin receptors. Genetic insights into serotonin function. Current Biology : Cb. 5: 997-9. PMID 8542294 DOI: 10.1016/S0960-9822(95)00199-0 |
0.363 |
|
| 1995 |
Li XC, Giot JF, Kuhl D, Hen R, Kandel ER. Cloning and characterization of two related serotonergic receptors from the brain and the reproductive system of Aplysia that activate phospholipase C. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 7585-91. PMID 7472509 DOI: 10.1523/Jneurosci.15-11-07585.1995 |
0.43 |
|
| 1995 |
Grailhe R, Hen R. 5-HT receptor knockouts: Constitutive, inducible or tissue-specific Seminars in Neuroscience. 7: 395-400. DOI: 10.1016/1044-5765(95)90003-9 |
0.346 |
|
| 1994 |
Saudou F, Amara DA, Dierich A, LeMeur M, Ramboz S, Segu L, Buhot MC, Hen R. Enhanced aggressive behavior in mice lacking 5-HT1B receptor. Science (New York, N.Y.). 265: 1875-8. PMID 8091214 DOI: 10.1126/Science.8091214 |
0.669 |
|
| 1994 |
Saudou F, Hen R. 5-Hydroxytryptamine receptor subtypes in vertebrates and invertebrates. Neurochemistry International. 25: 503-32. PMID 7894328 DOI: 10.1016/0197-0186(94)90150-3 |
0.567 |
|
| 1994 |
Saudou F, Hen R. 5-Hydroxytryptamine receptor subtypes: molecular and functional diversity. Advances in Pharmacology (San Diego, Calif.). 30: 327-80. PMID 7833295 DOI: 10.1016/S1054-3589(08)60178-7 |
0.58 |
|
| 1993 |
Duclos F, Boschert U, Sirugo G, Mandel JL, Hen R, Koenig M. Gene in the region of the Friedreich ataxia locus encodes a putative transmembrane protein expressed in the nervous system. Proceedings of the National Academy of Sciences of the United States of America. 90: 109-13. PMID 7678331 DOI: 10.1073/Pnas.90.1.109 |
0.518 |
|
| 1992 |
Maroteaux L, Saudou F, Amlaiky N, Boschert U, Plassat JL, Hen R. Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers. Proceedings of the National Academy of Sciences of the United States of America. 89: 3020-4. PMID 1557407 DOI: 10.1073/Pnas.89.7.3020 |
0.578 |
|
| 1992 |
Saudou F, Boschert U, Amlaiky N, Plassat JL, Hen R. A family of Drosophila serotonin receptors with distinct intracellular signalling properties and expression patterns. The Embo Journal. 11: 7-17. PMID 1310937 DOI: 10.1002/J.1460-2075.1992.Tb05021.X |
0.584 |
|
| 1990 |
Saudou F, Amlaiky N, Plassat JL, Borrelli E, Hen R. Cloning and characterization of a Drosophila tyramine receptor. The Embo Journal. 9: 3611-7. PMID 2170118 DOI: 10.1002/J.1460-2075.1990.Tb07572.X |
0.549 |
|
| 1989 |
Hen R, Axel R, Obici S. Activation of the beta 2-adrenergic receptor promotes growth and differentiation in thyroid cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 4785-8. PMID 2471981 DOI: 10.1073/Pnas.86.12.4785 |
0.47 |
|
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