Zhengui Xia - Publications

Affiliations: 
Toxicology University of Washington, Seattle, Seattle, WA 
Area:
Neuronal Apoptosis and stem cell biology

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Year Citation  Score
2020 Wang H, Matsushita MT, Zhang L, Abel GM, Mommer BC, Huddy TF, Storm DR, Xia Z. Inducible and conditional stimulation of adult hippocampal neurogenesis rescues Cadmium-induced impairments of adult hippocampal neurogenesis and hippocampus-dependent memory in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32617577 DOI: 10.1093/Toxsci/Kfaa104  0.357
2019 Wang H, Abel GM, Storm DR, Xia Z. Cadmium Exposure Impairs Adult Hippocampal Neurogenesis. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31271426 DOI: 10.1093/Toxsci/Kfz152  0.408
2019 Zhang L, Chen X, Sindreu C, Lu S, Storm DR, Zweifel LS, Xia Z. Dynamics of a hippocampal neuronal ensemble encoding trace fear memory revealed by in vivo Ca2+ imaging. Plos One. 14: e0219152. PMID 31269057 DOI: 10.1371/Journal.Pone.0219152  0.387
2018 Giurisato E, Xu Q, Lonardi S, Telfer B, Russo I, Pearson A, Finegan KG, Wang W, Wang J, Gray NS, Vermi W, Xia Z, Tournier C. Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507229 DOI: 10.1073/Pnas.1707929115  0.399
2017 Engstrom AK, Xia Z. Lead exposure in late adolescence through adulthood impairs short-term spatial memory and the neuronal differentiation of adult-born cells in C57BL/6 male mice. Neuroscience Letters. PMID 28970130 DOI: 10.1016/J.Neulet.2017.09.060  0.352
2017 Xia Z, Storm D. Role of Circadian Rhythm and REM Sleep For Memory Consolidation. Neuroscience Research. PMID 28434990 DOI: 10.1016/J.Neures.2017.04.011  0.338
2017 Choi WS, Kim HW, Tronche F, Palmiter RD, Storm DR, Xia Z. Conditional deletion of Ndufs4 in dopaminergic neurons promotes Parkinson's disease-like non-motor symptoms without loss of dopamine neurons. Scientific Reports. 7: 44989. PMID 28327638 DOI: 10.1038/Srep44989  0.439
2017 Wang H, Engstrom AK, Xia Z. Cadmium impairs the survival and proliferation of cultured adult subventricular neural stem cells through activation of the JNK and p38 MAP kinases. Toxicology. PMID 28163110 DOI: 10.1016/J.Tox.2017.01.013  0.408
2015 Zou J, Wang W, Pan YW, Abel GM, Storm DR, Xia Z. Conditional Inhibition of Adult Neurogenesis by Inducible and Targeted Deletion of ERK5 MAP Kinase Is Not Associated with Anxiety/Depression-Like Behaviors(1,2). Eneuro. 2. PMID 26464972 DOI: 10.1523/ENEURO.0014-14.2015  0.512
2015 Kim HW, Choi WS, Sorscher N, Park HJ, Tronche F, Palmiter RD, Xia Z. Genetic reduction of mitochondrial complex I function does not lead to loss of dopamine neurons in vivo. Neurobiology of Aging. PMID 26070241 DOI: 10.1016/J.Neurobiolaging.2015.05.008  0.765
2015 Wang W, Lu S, Li T, Pan YW, Zou J, Abel GM, Xu L, Storm DR, Xia Z. Inducible activation of ERK5 MAP kinase enhances adult neurogenesis in the olfactory bulb and improves olfactory function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 7833-49. PMID 25995470 DOI: 10.1523/Jneurosci.3745-14.2015  0.605
2015 Engstrom A, Wang H, Xia Z. Lead decreases cell survival, proliferation, and neuronal differentiation of primary cultured adult neural precursor cells through activation of the JNK and p38 MAP kinases. Toxicology in Vitro : An International Journal Published in Association With Bibra. 29: 1146-55. PMID 25967738 DOI: 10.1016/J.Tiv.2015.05.001  0.51
2015 Luo J, Chen X, Pan YW, Lu S, Xia Z, Storm DR. The type 3 adenylyl cyclase is required for the survival and maturation of newly generated granule cells in the olfactory bulb. Plos One. 10: e0122057. PMID 25807252 DOI: 10.1371/Journal.Pone.0122057  0.552
2015 Zou J, Wang W, Pan YW, Lu S, Xia Z. Methods to measure olfactory behavior in mice. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. 63: 11.18.1-11.18.21. PMID 25645244 DOI: 10.1002/0471140856.Tx1118S63  0.48
2015 Choi WS, Kim HW, Xia Z. JNK inhibition of VMAT2 contributes to rotenone-induced oxidative stress and dopamine neuron death. Toxicology. 328: 75-81. PMID 25496994 DOI: 10.1016/J.Tox.2014.12.005  0.523
2015 Engstrom A, Wang H, Xia Z. Lead decreases cell survival, proliferation, and neuronal differentiation of primary cultured adult neural precursor cells through activation of the JNK and p38 MAP kinases Toxicology in Vitro. 29: 1146-1155. DOI: 10.1016/j.tiv.2015.05.001  0.411
2014 Choi WS, Xia Z. Maneb-induced dopaminergic neuronal death is not affected by loss of mitochondrial complex I activity: results from primary mesencephalic dopaminergic neurons cultured from individual Ndufs4+/+ and Ndufs4-/- mouse embryos. Neuroreport. 25: 1350-5. PMID 25275677 DOI: 10.1097/Wnr.0000000000000271  0.476
2014 Wang W, Pan YW, Zou J, Li T, Abel GM, Palmiter RD, Storm DR, Xia Z. Genetic activation of ERK5 MAP kinase enhances adult neurogenesis and extends hippocampus-dependent long-term memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2130-47. PMID 24501354 DOI: 10.1523/Jneurosci.3324-13.2014  0.588
2013 Zou J, Storm DR, Xia Z. Conditional deletion of ERK5 MAP kinase in the nervous system impairs pheromone information processing and pheromone-evoked behaviors. Plos One. 8: e76901. PMID 24130808 DOI: 10.1371/Journal.Pone.0076901  0.384
2013 Pan YW, Storm DR, Xia Z. Role of adult neurogenesis in hippocampus-dependent memory, contextual fear extinction and remote contextual memory: new insights from ERK5 MAP kinase. Neurobiology of Learning and Memory. 105: 81-92. PMID 23871742 DOI: 10.1016/J.Nlm.2013.07.011  0.572
2013 Choi WS, Kim HW, Xia Z. Preparation of primary cultured dopaminergic neurons from mouse brain. Methods in Molecular Biology (Clifton, N.J.). 1018: 61-9. PMID 23681617 DOI: 10.1007/978-1-62703-444-9_6  0.486
2013 Pan YW, Wang W, Xia Z. Assessment of adult neurogenesis in mice. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit12.20. PMID 23670864 DOI: 10.1002/0471140856.Tx1220S56  0.556
2013 Li T, Pan YW, Wang W, Abel G, Zou J, Xu L, Storm DR, Xia Z. Targeted deletion of the ERK5 MAP kinase impairs neuronal differentiation, migration, and survival during adult neurogenesis in the olfactory bulb. Plos One. 8: e61948. PMID 23630619 DOI: 10.1371/Journal.Pone.0061948  0.653
2013 Li T, Wang W, Pan YW, Xu L, Xia Z. A hydroxylated metabolite of flame-retardant PBDE-47 decreases the survival, proliferation, and neuronal differentiation of primary cultured adult neural stem cells and interferes with signaling of ERK5 MAP kinase and neurotrophin 3. Toxicological Sciences : An Official Journal of the Society of Toxicology. 134: 111-24. PMID 23564643 DOI: 10.1093/Toxsci/Kft083  0.632
2013 Wang W, Pan YW, Wietecha T, Zou J, Abel GM, Kuo CT, Xia Z. Extracellular signal-regulated kinase 5 (ERK5) mediates prolactin-stimulated adult neurogenesis in the subventricular zone and olfactory bulb. The Journal of Biological Chemistry. 288: 2623-31. PMID 23223235 DOI: 10.1074/Jbc.M112.401091  0.618
2012 Pan YW, Storm DR, Xia Z. The maintenance of established remote contextual fear memory requires ERK5 MAP kinase and ongoing adult neurogenesis in the hippocampus. Plos One. 7: e50455. PMID 23189204 DOI: 10.1371/Journal.Pone.0050455  0.523
2012 Pan YW, Kuo CT, Storm DR, Xia Z. Inducible and targeted deletion of the ERK5 MAP kinase in adult neurogenic regions impairs adult neurogenesis in the olfactory bulb and several forms of olfactory behavior. Plos One. 7: e49622. PMID 23185386 DOI: 10.1371/Journal.Pone.0049622  0.582
2012 Xia Z, Storm DR. Role of signal transduction crosstalk between adenylyl cyclase and MAP kinase in hippocampus-dependent memory. Learning & Memory (Cold Spring Harbor, N.Y.). 19: 369-74. PMID 22904367 DOI: 10.1101/Lm.027128.112  0.402
2012 Pan YW, Zou J, Wang W, Sakagami H, Garelick MG, Abel G, Kuo CT, Storm DR, Xia Z. Inducible and conditional deletion of extracellular signal-regulated kinase 5 disrupts adult hippocampal neurogenesis. The Journal of Biological Chemistry. 287: 23306-17. PMID 22645146 DOI: 10.1074/Jbc.M112.344762  0.683
2012 Pan YW, Chan GC, Kuo CT, Storm DR, Xia Z. Inhibition of adult neurogenesis by inducible and targeted deletion of ERK5 mitogen-activated protein kinase specifically in adult neurogenic regions impairs contextual fear extinction and remote fear memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6444-55. PMID 22573667 DOI: 10.1523/Jneurosci.6076-11.2012  0.565
2012 Zou J, Pan YW, Wang Z, Chang SY, Wang W, Wang X, Tournier C, Storm DR, Xia Z. Targeted deletion of ERK5 MAP kinase in the developing nervous system impairs development of GABAergic interneurons in the main olfactory bulb and behavioral discrimination between structurally similar odorants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4118-32. PMID 22442076 DOI: 10.1523/Jneurosci.6260-11.2012  0.613
2011 Choi WS, Klintworth HM, Xia Z. JNK3-mediated apoptotic cell death in primary dopaminergic neurons. Methods in Molecular Biology (Clifton, N.J.). 758: 279-92. PMID 21815073 DOI: 10.1007/978-1-61779-170-3_19  0.826
2011 Choi WS, Palmiter RD, Xia Z. Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model. The Journal of Cell Biology. 192: 873-82. PMID 21383081 DOI: 10.1083/Jcb.201009132  0.444
2010 Choi WS, Abel G, Klintworth H, Flavell RA, Xia Z. JNK3 mediates paraquat- and rotenone-induced dopaminergic neuron death. Journal of Neuropathology and Experimental Neurology. 69: 511-20. PMID 20418776 DOI: 10.1097/Nen.0B013E3181Db8100  0.825
2009 Klintworth H, Garden G, Xia Z. Rotenone and paraquat do not directly activate microglia or induce inflammatory cytokine release. Neuroscience Letters. 462: 1-5. PMID 19559752 DOI: 10.1016/J.Neulet.2009.06.065  0.777
2009 Cundiff P, Liu L, Wang Y, Zou J, Pan YW, Abel G, Duan X, Ming GL, Englund C, Hevner R, Xia Z. ERK5 MAP kinase regulates neurogenin1 during cortical neurogenesis. Plos One. 4: e5204. PMID 19365559 DOI: 10.1371/Journal.Pone.0005204  0.806
2008 Choi WS, Kruse SE, Palmiter RD, Xia Z. Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat. Proceedings of the National Academy of Sciences of the United States of America. 105: 15136-41. PMID 18812510 DOI: 10.1073/Pnas.0807581105  0.504
2008 Faigle R, Liu L, Cundiff P, Funa K, Xia Z. Opposing effects of retinoid signaling on astrogliogenesis in embryonic day 13 and 17 cortical progenitor cells. Journal of Neurochemistry. 106: 1681-98. PMID 18564368 DOI: 10.1111/J.1471-4159.2008.05525.X  0.753
2008 Cai B, Xia Z. p38 MAP kinase mediates arsenite-induced apoptosis through FOXO3a activation and induction of Bim transcription. Apoptosis : An International Journal On Programmed Cell Death. 13: 803-10. PMID 18465250 DOI: 10.1007/S10495-008-0218-5  0.615
2007 Wang Y, Liu L, Xia Z. Brain-derived neurotrophic factor stimulates the transcriptional and neuroprotective activity of myocyte-enhancer factor 2C through an ERK1/2-RSK2 signaling cascade. Journal of Neurochemistry. 102: 957-66. PMID 17630987 DOI: 10.1111/J.1471-4159.2007.04606.X  0.672
2007 Cude K, Wang Y, Choi HJ, Hsuan SL, Zhang H, Wang CY, Xia Z. Regulation of the G2-M cell cycle progression by the ERK5-NFkappaB signaling pathway. The Journal of Cell Biology. 177: 253-64. PMID 17452529 DOI: 10.1083/Jcb.200609166  0.753
2007 Klintworth H, Newhouse K, Li T, Choi WS, Faigle R, Xia Z. Activation of c-Jun N-terminal protein kinase is a common mechanism underlying paraquat- and rotenone-induced dopaminergic cell apoptosis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 97: 149-62. PMID 17324951 DOI: 10.1093/Toxsci/Kfm029  0.814
2006 Wang Y, Su B, Xia Z. Brain-derived neurotrophic factor activates ERK5 in cortical neurons via a Rap1-MEKK2 signaling cascade. The Journal of Biological Chemistry. 281: 35965-74. PMID 17003042 DOI: 10.1074/Jbc.M605503200  0.688
2006 Cai B, Chang SH, Becker EB, Bonni A, Xia Z. p38 MAP kinase mediates apoptosis through phosphorylation of BimEL at Ser-65. The Journal of Biological Chemistry. 281: 25215-22. PMID 16818494 DOI: 10.1074/Jbc.M512627200  0.633
2006 Liu L, Cundiff P, Abel G, Wang Y, Faigle R, Sakagami H, Xu M, Xia Z. Extracellular signal-regulated kinase (ERK) 5 is necessary and sufficient to specify cortical neuronal fate. Proceedings of the National Academy of Sciences of the United States of America. 103: 9697-702. PMID 16766652 DOI: 10.1073/Pnas.0603373103  0.827
2006 Hsuan SL, Klintworth HM, Xia Z. Basic fibroblast growth factor protects against rotenone-induced dopaminergic cell death through activation of extracellular signal-regulated kinases 1/2 and phosphatidylinositol-3 kinase pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4481-91. PMID 16641227 DOI: 10.1523/Jneurosci.4922-05.2006  0.829
2005 Tang X, Wang X, Gong X, Tong M, Park D, Xia Z, Mao Z. Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4823-34. PMID 15888658 DOI: 10.1523/Jneurosci.1331-05.2005  0.555
2004 Chang SH, Poser S, Xia Z. A novel role for serum response factor in neuronal survival. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2277-85. PMID 14999078 DOI: 10.1523/Jneurosci.4868-03.2004  0.56
2004 Newhouse K, Hsuan SL, Chang SH, Cai B, Wang Y, Xia Z. Rotenone-induced apoptosis is mediated by p38 and JNK MAP kinases in human dopaminergic SH-SY5Y cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 79: 137-46. PMID 14976342 DOI: 10.1093/Toxsci/Kfh089  0.748
2004 Caughlan A, Newhouse K, Namgung U, Xia Z. Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases. Toxicological Sciences : An Official Journal of the Society of Toxicology. 78: 125-34. PMID 14691213 DOI: 10.1093/Toxsci/Kfh038  0.532
2003 Liu L, Cavanaugh JE, Wang Y, Sakagami H, Mao Z, Xia Z. ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons. Proceedings of the National Academy of Sciences of the United States of America. 100: 8532-7. PMID 12826611 DOI: 10.1073/Pnas.1332804100  0.699
2003 Poser S, Impey S, Xia Z, Storm DR. Brain-derived neurotrophic factor protection of cortical neurons from serum withdrawal-induced apoptosis is inhibited by cAMP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4420-7. PMID 12805282 DOI: 10.1523/Jneurosci.23-11-04420.2003  0.565
2003 Namgung U, Kim DH, Lim SR, Xia Z. Blockade of calcium entry accelerates arsenite-mediated apoptosis in rat cerebellar granule cells. Molecules and Cells. 15: 256-61. PMID 12803490  0.368
2003 Poser S, Impey S, Xia Z, Storm DR. Brain-Derived Neurotrophic Factor Protection of Cortical Neurons from Serum Withdrawal-Induced Apoptosis Is Inhibited by cAMP The Journal of Neuroscience. 23: 4420-4427. DOI: 10.1523/JNEUROSCI.23-11-04420.2003  0.369
2002 Hetman M, Hsuan SL, Habas A, Higgins MJ, Xia Z. ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons. The Journal of Biological Chemistry. 277: 49577-84. PMID 12393899 DOI: 10.1074/Jbc.M111227200  0.591
2002 Ghahremani MH, Keramaris E, Shree T, Xia Z, Davis RJ, Flavell R, Slack RS, Park DS. Interaction of the c-Jun/JNK pathway and cyclin-dependent kinases in death of embryonic cortical neurons evoked by DNA damage. The Journal of Biological Chemistry. 277: 35586-96. PMID 12091388 DOI: 10.1074/Jbc.M204362200  0.502
2002 Kornhauser JM, Cowan CW, Shaywitz AJ, Dolmetsch RE, Griffith EC, Hu LS, Haddad C, Xia Z, Greenberg ME. CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphorylation events. Neuron. 34: 221-33. PMID 11970864 DOI: 10.1016/S0896-6273(02)00655-4  0.465
2002 Zhu Y, Mao XO, Sun Y, Xia Z, Greenberg DA. p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 and p53 in neurons. The Journal of Biological Chemistry. 277: 22909-14. PMID 11948180 DOI: 10.1074/jbc.M200042200  0.381
2002 Xia Z, Storm DR. CaRF: a neuronal transcription factor that CaREs. Neuron. 33: 315-6. PMID 11832218 DOI: 10.1016/S0896-6273(02)00578-0  0.36
2001 Mabuchi T, Kitagawa K, Kuwabara K, Takasawa K, Ohtsuki T, Xia Z, Storm D, Yanagihara T, Hori M, Matsumoto M. Phosphorylation of cAMP response element-binding protein in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9204-13. PMID 11717354 DOI: 10.1523/Jneurosci.21-23-09204.2001  0.509
2001 Namgung U, Xia Z. Arsenic induces apoptosis in rat cerebellar neurons via activation of JNK3 and p38 MAP kinases Toxicology and Applied Pharmacology. 174: 130-138. PMID 11446828 DOI: 10.1006/Taap.2001.9200  0.546
2001 Figueroa-Masot XA, Hetman M, Higgins MJ, Kokot N, Xia Z. Taxol induces apoptosis in cortical neurons by a mechanism independent of Bcl-2 phosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 4657-67. PMID 11425893 DOI: 10.1523/Jneurosci.21-13-04657.2001  0.821
2001 Chan GC, Lernmark U, Xia Z, Storm DR. DNA elements of the type 1 adenylyl cyclase gene locus enhance reporter gene expression in neurons and pinealocytes. The European Journal of Neuroscience. 13: 2054-66. PMID 11422446 DOI: 10.1046/J.0953-816X.2001.01578.X  0.381
2001 Cavanaugh JE, Ham J, Hetman M, Poser S, Yan C, Xia Z. Differential regulation of mitogen-activated protein kinases ERK1/2 and ERK5 by neurotrophins, neuronal activity, and cAMP in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 434-43. PMID 11160424 DOI: 10.1523/Jneurosci.21-02-00434.2001  0.599
2001 Figueroa-Masot XA, Hetman M, Higgins MJ, Kokot N, Xia Z. Taxol Induces Apoptosis in Cortical Neurons by a Mechanism Independent of Bcl-2 Phosphorylation The Journal of Neuroscience. 21: 4657-4667. DOI: 10.1523/JNEUROSCI.21-13-04657.2001  0.433
2001 Cavanaugh JE, Ham J, Hetman M, Poser S, Yan C, Xia Z. Differential Regulation of Mitogen-Activated Protein Kinases ERK1/2 and ERK5 by Neurotrophins, Neuronal Activity, and cAMP in Neurons The Journal of Neuroscience. 21: 434-443. DOI: 10.1523/JNEUROSCI.21-02-00434.2001  0.471
2000 Wong ST, Trinh K, Hacker B, Chan GC, Lowe G, Gaggar A, Xia Z, Gold GH, Storm DR. Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice. Neuron. 27: 487-97. PMID 11055432 DOI: 10.1016/S0896-6273(00)00060-X  0.322
2000 Poser S, Impey S, Trinh K, Xia Z, Storm DR. SRF-dependent gene expression is required for PI3-kinase-regulated cell proliferation. The Embo Journal. 19: 4955-66. PMID 10990459 DOI: 10.1093/Emboj/19.18.4955  0.437
2000 Ghatan S, Larner S, Kinoshita Y, Hetman M, Patel L, Xia Z, Youle RJ, Morrison RS. p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons. The Journal of Cell Biology. 150: 335-47. PMID 10908576 DOI: 10.1083/Jcb.150.2.335  0.553
2000 Namgung U, Xia Z. Arsenite-Induced Apoptosis in Cortical Neurons Is Mediated by c-Jun N-Terminal Protein Kinase 3 and p38 Mitogen-Activated Protein Kinase The Journal of Neuroscience. 20: 6442-6451. DOI: 10.1523/Jneurosci.20-17-06442.2000  0.545
2000 Hetman M, Cavanaugh JE, Kimelman D, Xia Z. Role of Glycogen Synthase Kinase-3β in Neuronal Apoptosis Induced by Trophic Withdrawal The Journal of Neuroscience. 20: 2567-2574. DOI: 10.1523/Jneurosci.20-07-02567.2000  0.574
1999 Hetman M, Kanning K, Cavanaugh JE, Xia Z. Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. The Journal of Biological Chemistry. 274: 22569-80. PMID 10428835 DOI: 10.1074/Jbc.274.32.22569  0.574
1999 Yue TL, Ni J, Romanic AM, Gu JL, Keller P, Wang C, Kumar S, Yu GL, Hart TK, Wang X, Xia Z, DeWolf WE, Feuerstein GZ. TL1, a novel tumor necrosis factor-like cytokine, induces apoptosis in endothelial cells. Involvement of activation of stress protein kinases (stress-activated protein kinase and p38 mitogen-activated protein kinase) and caspase-3-like protease. The Journal of Biological Chemistry. 274: 1479-86. PMID 9880523 DOI: 10.1074/Jbc.274.3.1479  0.452
1998 Xing J, Kornhauser JM, Xia Z, Thiele EA, Greenberg ME. Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation. Molecular and Cellular Biology. 18: 1946-55. PMID 9528766 DOI: 10.1128/Mcb.18.4.1946  0.459
1997 Dickens M, Rogers JS, Cavanagh J, Raitano A, Xia Z, Halpern JR, Greenberg ME, Sawyers CL, Davis RJ. A cytoplasmic inhibitor of the JNK signal transduction pathway. Science (New York, N.Y.). 277: 693-6. PMID 9235893 DOI: 10.1126/Science.277.5326.693  0.449
1997 Xia Z, Storm DR. Calmodulin-regulated adenylyl cyclases and neuromodulation. Current Opinion in Neurobiology. 7: 391-6. PMID 9232797 DOI: 10.1016/S0959-4388(97)80068-2  0.309
1996 Xia Z, Dudek H, Miranti CK, Greenberg ME. Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 5425-36. PMID 8757255 DOI: 10.1523/Jneurosci.16-17-05425.1996  0.519
1995 Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science (New York, N.Y.). 270: 1326-31. PMID 7481820 DOI: 10.1126/Science.270.5240.1326  0.525
1995 Xia Z, Choi EJ, Storm DR, Blazynski C. Do the calmodulin-stimulated adenylyl cyclases play a role in neuroplasticity? Behavioral and Brain Sciences. 18: 429-440. DOI: 10.1017/S0140525X00039194  0.361
1993 Choi EJ, Xia Z, Villacres EC, Storm DR. The regulatory diversity of the mammalian adenylyl cyclases. Current Opinion in Cell Biology. 5: 269-73. PMID 8507499 DOI: 10.1016/0955-0674(93)90115-7  0.326
1992 Xia Z, Choi EJ, Wang F, Storm DR. The type III calcium/calmodulin-sensitive adenylyl cyclase is not specific to olfactory sensory neurons. Neuroscience Letters. 144: 169-73. PMID 1436697 DOI: 10.1016/0304-3940(92)90742-P  0.306
Low-probability matches (unlikely to be authored by this person)
2012 Chen X, Xia Z, Storm DR. Stimulation of electro-olfactogram responses in the main olfactory epithelia by airflow depends on the type 3 adenylyl cyclase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15769-78. PMID 23136416 DOI: 10.1523/Jneurosci.2180-12.2012  0.296
2019 Zhang L, Wang H, Abel GM, Storm DR, Xia Z. The Effects of Gene-Environment Interactions Between Cadmium Exposure and Apolipoprotein E4 on Memory in a Mouse Model of Alzheimer's Disease. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31626305 DOI: 10.1093/Toxsci/Kfz218  0.296
1995 Xia Z, Storm DR. Evidence that the type I adenylyl cyclase may be important for neuroplasticity: Mutant mice deficient in the gene for type I adenylyl cyclase show altered behavior and LTP Behavioral and Brain Sciences. 18: 498-500. DOI: 10.1017/S0140525X0003956X  0.293
1995 Wu ZL, Thomas SA, Villacres EC, Xia Z, Simmons ML, Chavkin C, Palmiter RD, Storm DR. Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 92: 220-4. PMID 7816821 DOI: 10.1073/Pnas.92.1.220  0.291
2001 Mabuchi T, Kitagawa K, Kuwabara K, Takasawa K, Ohtsuki T, Xia Z, Storm D, Yanagihara T, Hori M, Matsumoto M. Phosphorylation of cAMP Response Element-Binding Protein in Hippocampal Neurons as a Protective Response after Exposure to GlutamateIn Vitroand IschemiaIn Vivo The Journal of Neuroscience. 21: 9204-9213. DOI: 10.1523/JNEUROSCI.21-23-09204.2001  0.287
2015 Yu AK, Song L, Murray KD, van der List D, Sun C, Shen Y, Xia Z, Cortopassi GA. Mitochondrial complex I deficiency leads to inflammation and retinal ganglion cell death in the Ndufs4 mouse. Human Molecular Genetics. 24: 2848-60. PMID 25652399 DOI: 10.1093/Hmg/Ddv045  0.285
1993 Xia Z, Choi EJ, Wang F, Blazynski C, Storm DR. Type I calmodulin-sensitive adenylyl cyclase is neural specific. Journal of Neurochemistry. 60: 305-11. PMID 8417150 DOI: 10.1111/J.1471-4159.1993.Tb05852.X  0.285
1991 Xia ZG, Refsdal CD, Merchant KM, Dorsa DM, Storm DR. Distribution of mRNA for the calmodulin-sensitive adenylate cyclase in rat brain: expression in areas associated with learning and memory. Neuron. 6: 431-43. PMID 2001286 DOI: 10.1016/0896-6273(91)90251-T  0.284
1992 Choi EJ, Xia Z, Storm DR. Stimulation of the type III olfactory adenylyl cyclase by calcium and calmodulin. Biochemistry. 31: 6492-8. PMID 1633161 DOI: 10.1021/Bi00143A019  0.267
1993 Villacres EC, Xia Z, Bookbinder LH, Edelhoff S, Disteche CM, Storm DR. Cloning, chromosomal mapping, and expression of human fetal brain type I adenylyl cyclase. Genomics. 16: 473-8. PMID 8314585 DOI: 10.1006/Geno.1993.1213  0.264
2009 Wang Z, Li V, Chan GC, Phan T, Nudelman AS, Xia Z, Storm DR. Adult type 3 adenylyl cyclase-deficient mice are obese. Plos One. 4: e6979. PMID 19750222 DOI: 10.1371/Journal.Pone.0006979  0.259
2005 Xia Z, Storm DR. The role of calmodulin as a signal integrator for synaptic plasticity. Nature Reviews. Neuroscience. 6: 267-76. PMID 15803158 DOI: 10.1038/Nrn1647  0.255
2017 Engstrom AK, Snyder JM, Maeda N, Xia Z. Gene-environment interaction between lead and Apolipoprotein E4 causes cognitive behavior deficits in mice. Molecular Neurodegeneration. 12: 14. PMID 28173832 DOI: 10.1186/S13024-017-0155-2  0.233
2017 Engstrom AK, Snyder JM, Maeda N, Xia Z. Correction to: Gene-environment interaction between lead and Apolipoprotein E4 causes cognitive behavior deficits in mice. Molecular Neurodegeneration. 12: 81. PMID 29100536 DOI: 10.1186/S13024-017-0223-7  0.227
2017 Wang H, Zhang L, Abel GM, Storm DR, Xia Z. Cadmium exposure impairs cognition and olfactory memory in male C57BL/6 mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29029324 DOI: 10.1093/Toxsci/Kfx202  0.223
2007 DiRocco DP, Xia Z. Alpha males win again. Nature Neuroscience. 10: 938-40. PMID 17657234 DOI: 10.1038/Nn0807-938  0.221
2023 Matsushita MT, Wang H, Abel GM, Xia Z. Inducible and Conditional Activation of Adult Neurogenesis Rescues Cadmium-Induced Hippocampus-Dependent Memory Deficits in ApoE4-KI Mice. International Journal of Molecular Sciences. 24. PMID 37298071 DOI: 10.3390/ijms24119118  0.217
2020 Wang H, Matsushita MT, Abel GM, Storm DR, Xia Z. Inducible and conditional activation of ERK5 MAP Kinase rescues mice from cadmium-induced olfactory memory deficits. Neurotoxicology. PMID 33039505 DOI: 10.1016/j.neuro.2020.09.038  0.204
1998 Xia Z, Kam CM, Huang C, Powers JC, Mandle RJ, Stevens RL, Lieberman J. Expression and purification of enzymatically active recombinant granzyme B in a baculovirus system. Biochemical and Biophysical Research Communications. 243: 384-9. PMID 9480818 DOI: 10.1006/Bbrc.1998.8102  0.184
1997 Xia Z, Depierre JW, Nässberger L. The tricyclic antidepressants clomipramine and citalopram induce apoptosis in cultured human lymphocytes. The Journal of Pharmacy and Pharmacology. 48: 115-6. PMID 8722508 DOI: 10.1111/j.2042-7158.1996.tb05889.x  0.181
2012 Hansson AL, Xia Z, Berglund MC, Bergstrand A, Depierre JW, Nässberger L. Reduced cell survival and morphological alterations induced by three tricyclic antidepressants in human peripheral monocytes and lymphocytes and in cell lines derived from these cell types. Toxicology in Vitro : An International Journal Published in Association With Bibra. 11: 21-31. PMID 20654293 DOI: 10.1016/S0887-2333(97)00003-9  0.169
1996 Xia Z, Ghildyal N, Austen KF, Stevens RL. Post-transcriptional regulation of chymase expression in mast cells. A cytokine-dependent mechanism for controlling the expression of granule neutral proteases of hematopoietic cells. The Journal of Biological Chemistry. 271: 8747-53. PMID 8621509 DOI: 10.1074/jbc.271.15.8747  0.159
2021 Wang H, Abel GM, Storm DR, Xia Z. Adolescent cadmium exposure impairs cognition and hippocampal neurogenesis in C57BL/6 mice. Environmental Toxicology. PMID 34741586 DOI: 10.1002/tox.23402  0.145
2021 Zhang A, Matsushita M, Zhang L, Wang H, Shi X, Gu H, Xia Z, Cui JY. Cadmium exposure modulates the gut-liver axis in an Alzheimer's disease mouse model. Communications Biology. 4: 1398. PMID 34912029 DOI: 10.1038/s42003-021-02898-1  0.138
2013 Chen X, Xia Z, Storm DR. Electroolfactogram (EOG) Recording in the Mouse Main Olfactory Epithelium. Bio-Protocol. 3. PMID 27430002  0.109
2022 Wang H, Zhang L, Xia Z, Cui JY. Effects of chronic cadmium exposure on brain and liver transporters and drug-metabolizing enzymes in male and female mice genetically predisposed to Alzheimer's disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 35878927 DOI: 10.1124/dmd.121.000453  0.076
2014 Luo X, Tai W, Sun L, Xia Z, Chung KS, Cheung CW. Central administration of CXCR4 antagonist prevents the development of peripheral neuropathic pain and modulates the spinal expression of neuropeptides and pro-inflammatory cytokines in mice European Journal of Anaesthesiology. 31: 143. DOI: 10.1097/00003643-201406001-00404  0.071
2005 Munsat T, Mazzucato E, Park H, Domier C, Johnson M, Luhmann N, Wang J, Xia Z, Classen I, Donne A, van de Pol M. 2-D imaging of electron temperature in Tokamak plasmas Ieee Transactions On Plasma Science. 33: 466-467. DOI: 10.1109/Tps.2005.845948  0.03
2006 Fredrickson CK, Xia Z, Das C, Ferguson R, Tavares FT, Fan ZH. Effects of fabrication process parameters on the properties of cyclic olefin copolymer microfluidic devices Journal of Microelectromechanical Systems. 15: 1060-1068. DOI: 10.1109/Jmems.2006.880352  0.024
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