Vassilis Pachnis - Publications

Affiliations: 
NIMR 
Area:
Develoment
Website:
http://www.nimr.mrc.ac.uk/molneurobiol/

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Laddach A, Chng SH, Lasrado R, Progatzky F, Shapiro M, Erickson A, Sampedro Castaneda M, Artemov AV, Bon-Frauches AC, Amaniti EM, Kleinjung J, Boeing S, Ultanir S, Adameyko I, Pachnis V. A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia. Nature Communications. 14: 5904. PMID 37737269 DOI: 10.1038/s41467-023-41492-3  0.352
2022 Natarajan D, McCann C, Dattani J, Pachnis V, Thapar N. Multiple Roles of Ret Signalling During Enteric Neurogenesis. Frontiers in Molecular Neuroscience. 15: 832317. PMID 35694443 DOI: 10.3389/fnmol.2022.832317  0.367
2020 McCallum S, Obata Y, Fourli E, Boeing S, Peddie CJ, Xu Q, Horswell S, Kelsh R, Collinson L, Wilkinson D, Pin C, Pachnis V, Heanue TA. Enteric glia as a source of neural progenitors in adult zebrafish. Elife. 9. PMID 32851974 DOI: 10.7554/Elife.56086  0.453
2020 Obata Y, Pachnis V. Linking neurons to immunity: Lessons from . Proceedings of the National Academy of Sciences of the United States of America. 117: 19624-19626. PMID 32759220 DOI: 10.1073/pnas.2011637117  0.366
2020 Chng SH, Pachnis V. Enteric Nervous System: lessons from neurogenesis for reverse engineering and disease modelling and treatment. Current Opinion in Pharmacology. 50: 100-106. PMID 32240931 DOI: 10.1016/j.coph.2020.02.001  0.338
2020 Obata Y, Castaño Á, Boeing S, Bon-Frauches AC, Fung C, Fallesen T, de Agüero MG, Yilmaz B, Lopes R, Huseynova A, Horswell S, Maradana MR, Boesmans W, Vanden Berghe P, Murray AJ, ... ... Pachnis V, et al. Neuronal programming by microbiota regulates intestinal physiology. Nature. PMID 32025031 DOI: 10.1038/S41586-020-1975-8  0.438
2019 Denaxa M, Neves G, Burrone J, Pachnis V. Transplantation of Chemogenetically Engineered Cortical Interneuron Progenitors into Early Postnatal Mouse Brains. Journal of Visualized Experiments : Jove. PMID 31498303 DOI: 10.3791/59568  0.406
2019 Boesmans W, Hao MM, Fung C, Li Z, Van den Haute C, Tack J, Pachnis V, Vanden Berghe P. Structurally defined signaling in neuro-glia units in the enteric nervous system. Glia. PMID 30730592 DOI: 10.1002/glia.23596  0.42
2018 Denaxa M, Neves G, Burrone J, Pachnis V. Homeostatic Regulation of Interneuron Apoptosis During Cortical Development. Journal of Experimental Neuroscience. 12: 1179069518784277. PMID 30013387 DOI: 10.1177/1179069518784277  0.391
2018 Denaxa M, Neves G, Rabinowitz A, Kemlo S, Liodis P, Burrone J, Pachnis V. Modulation of Apoptosis Controls Inhibitory Interneuron Number in the Cortex. Cell Reports. 22: 1710-1721. PMID 29444425 DOI: 10.1016/J.Celrep.2018.01.064  0.35
2017 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundström E, Pachnis V, Marklund U. Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. PMID 29031500 DOI: 10.1053/J.Gastro.2017.10.005  0.47
2017 Lasrado R, Boesmans W, Kleinjung J, Pin C, Bell D, Bhaw L, McCallum S, Zong H, Luo L, Clevers H, Vanden Berghe P, Pachnis V. Lineage-dependent spatial and functional organization of the mammalian enteric nervous system. Science (New York, N.Y.). 356: 722-726. PMID 28522527 DOI: 10.1126/Science.Aam7511  0.417
2017 Veiga-Fernandes H, Pachnis V. Neuroimmune regulation during intestinal development and homeostasis. Nature Immunology. 18: 116-122. PMID 28092371 DOI: 10.1038/ni.3634  0.383
2017 Memic F, Knoflach V, Sadler R, Laranjeira C, Lefebvre V, Hjerling-Leffler J, Sundström E, Pachnis V, Marklund U. Sox6, a regulatory gene in the specification of gastric dopaminergic neurons Mechanisms of Development. 145: S122. DOI: 10.1016/J.Mod.2017.04.332  0.354
2017 Memic F, Knoflach V, Sadler R, Sundström E, Guillemot F, Pachnis V, Marklund U. Regulation of neural diversity by Ascl1 indicates strong intrinsic control of subtype specification in enteric progenitors during early bowel development Mechanisms of Development. 145: S121. DOI: 10.1016/j.mod.2017.04.329  0.369
2017 Knoflach V, Memic F, Sadler R, Pieters L, Laranjeira C, Sundström E, Pachnis V, Marklund U. Novel regulatory genes during neuronal diversification in the developing enteric nervous system Mechanisms of Development. 145: S119. DOI: 10.1016/j.mod.2017.04.322  0.418
2016 Heanue TA, Boesmans W, Bell DM, Kawakami K, Vanden Berghe P, Pachnis V. A Novel Zebrafish ret Heterozygous Model of Hirschsprung Disease Identifies a Functional Role for mapk10 as a Modifier of Enteric Nervous System Phenotype Severity. Plos Genetics. 12: e1006439. PMID 27902697 DOI: 10.1371/Journal.Pgen.1006439  0.434
2016 Konstantinidou C, Taraviras S, Pachnis V. Geminin prevents DNA damage in vagal neural crest cells to ensure normal enteric neurogenesis. Bmc Biology. 14: 94. PMID 27776507 DOI: 10.1186/s12915-016-0314-x  0.432
2016 Obata Y, Pachnis V. The Effect of Microbiota and the Immune System on the Development and Organization of the Enteric Nervous System. Gastroenterology. PMID 27521479 DOI: 10.1053/j.gastro.2016.07.044  0.352
2016 Kaucka M, Ivashkin E, Gyllborg D, Zikmund T, Tesarova M, Kaiser J, Xie M, Petersen J, Pachnis V, Nicolis SK, Yu T, Sharpe P, Arenas E, Brismar H, Blom H, et al. Analysis of neural crest-derived clones reveals novel aspects of facial development. Science Advances. 2: e1600060. PMID 27493992 DOI: 10.1126/Sciadv.1600060  0.372
2016 Uesaka T, Young HM, Pachnis V, Enomoto H. Development of the intrinsic and extrinsic innervation of the gut. Developmental Biology. PMID 27112528 DOI: 10.1016/j.ydbio.2016.04.016  0.443
2016 Memic F, Knoflach V, Sadler R, Tegerstedt G, Sundström E, Guillemot F, Pachnis V, Marklund U. Ascl1 Is Required for the Development of Specific Neuronal Subtypes in the Enteric Nervous System. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 4339-50. PMID 27076429 DOI: 10.1523/JNEUROSCI.0202-16.2016  0.483
2016 Burns AJ, Goldstein AM, Newgreen DF, Stamp L, Schafer KH, Metzger M, Hotta R, Young HM, Andrews PW, Thapar N, Belkind-Gerson J, Bondurand N, Bornstein JC, Chan WY, Cheah K, ... ... Pachnis V, et al. White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies. Developmental Biology. PMID 27059883 DOI: 10.1016/J.Ydbio.2016.04.001  0.331
2015 Stathopoulou A, Natarajan D, Nikolopoulou P, Patmanidi AL, Lygerou Z, Pachnis V, Taraviras S. Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis. Developmental Biology. PMID 26658318 DOI: 10.1016/j.ydbio.2015.11.023  0.419
2015 Kabouridis PS, Lasrado R, McCallum S, Chng SH, Snippert HJ, Clevers H, Pettersson S, Pachnis V. The gut microbiota keeps enteric glial cells on the move; prospective roles of the gut epithelium and immune system. Gut Microbes. 0. PMID 26558327 DOI: 10.1080/19490976.2015.1109767  0.335
2015 Ren Y, Suzuki H, Jagarlamudi K, Golnoski K, McGuire M, Lopes R, Pachnis V, Rajkovic A. Lhx8 regulates primordial follicle activation and postnatal folliculogenesis. Bmc Biology. 13: 39. PMID 26076587 DOI: 10.1186/s12915-015-0151-3  0.337
2015 Jiang Q, Arnold S, Heanue T, Kilambi KP, Doan B, Kapoor A, Ling AY, Sosa MX, Guy M, Jiang Q, Burzynski G, West K, Bessling S, Griseri P, Amiel J, ... ... Pachnis V, et al. Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability. American Journal of Human Genetics. 96: 581-96. PMID 25839327 DOI: 10.1016/J.Ajhg.2015.02.014  0.414
2015 Kabouridis PS, Pachnis V. Emerging roles of gut microbiota and the immune system in the development of the enteric nervous system. The Journal of Clinical Investigation. 125: 956-64. PMID 25729852 DOI: 10.1172/JCI76308  0.434
2015 Kabouridis PS, Lasrado R, McCallum S, Chng SH, Snippert HJ, Clevers H, Pettersson S, Pachnis V. Microbiota controls the homeostasis of glial cells in the gut lamina propria. Neuron. 85: 289-95. PMID 25578362 DOI: 10.1016/J.Neuron.2014.12.037  0.414
2015 Boesmans W, Lasrado R, Vanden Berghe P, Pachnis V. Heterogeneity and phenotypic plasticity of glial cells in the mammalian enteric nervous system. Glia. 63: 229-41. PMID 25161129 DOI: 10.1002/glia.22746  0.439
2014 Xu Q, Heanue T, Pachnis V. Travelling within the fetal gut: simple rules for an arduous journey. Bmc Biology. 12: 50. PMID 25184534 DOI: 10.1186/s12915-014-0050-z  0.348
2014 Kaukua N, Shahidi MK, Konstantinidou C, Dyachuk V, Kaucka M, Furlan A, An Z, Wang L, Hultman I, Ahrlund-Richter L, Blom H, Brismar H, Lopes NA, Pachnis V, Suter U, et al. Glial origin of mesenchymal stem cells in a tooth model system. Nature. 513: 551-4. PMID 25079316 DOI: 10.1038/Nature13536  0.34
2014 Dyachuk V, Furlan A, Shahidi MK, Giovenco M, Kaukua N, Konstantinidou C, Pachnis V, Memic F, Marklund U, Müller T, Birchmeier C, Fried K, Ernfors P, Adameyko I. Neurodevelopment. Parasympathetic neurons originate from nerve-associated peripheral glial progenitors. Science (New York, N.Y.). 345: 82-7. PMID 24925909 DOI: 10.1126/Science.1253281  0.444
2014 Tivodar S, Kalemaki K, Kounoupa Z, Vidaki M, Theodorakis K, Denaxa M, Kessaris N, de Curtis I, Pachnis V, Karagogeos D. Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons. Cerebral Cortex (New York, N.Y. : 1991). PMID 24626607 DOI: 10.1093/Cercor/Bhu037  0.391
2013 Sasselli V, Boesmans W, Vanden Berghe P, Tissir F, Goffinet AM, Pachnis V. Planar cell polarity genes control the connectivity of enteric neurons. The Journal of Clinical Investigation. 123: 1763-72. PMID 23478408 DOI: 10.1172/JCI66759  0.446
2013 Neves G, Shah MM, Liodis P, Achimastou A, Denaxa M, Roalfe G, Sesay A, Walker MC, Pachnis V. The LIM homeodomain protein Lhx6 regulates maturation of interneurons and network excitability in the mammalian cortex. Cerebral Cortex (New York, N.Y. : 1991). 23: 1811-23. PMID 22710612 DOI: 10.1093/Cercor/Bhs159  0.423
2012 Almeida AR, Arroz-Madeira S, Fonseca-Pereira D, Ribeiro H, Lasrado R, Pachnis V, Veiga-Fernandes H. RET/GFRα signals are dispensable for thymic T cell development in vivo. Plos One. 7: e52949. PMID 23300832 DOI: 10.1371/journal.pone.0052949  0.409
2012 Denaxa M, Kalaitzidou M, Garefalaki A, Achimastou A, Lasrado R, Maes T, Pachnis V. Maturation-promoting activity of SATB1 in MGE-derived cortical interneurons. Cell Reports. 2: 1351-62. PMID 23142661 DOI: 10.1016/j.celrep.2012.10.003  0.392
2012 Patel A, Harker N, Moreira-Santos L, Ferreira M, Alden K, Timmis J, Foster K, Garefalaki A, Pachnis P, Andrews P, Enomoto H, Milbrandt J, Pachnis V, Coles MC, Kioussis D, et al. Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems. Science Signaling. 5: ra55. PMID 22855506 DOI: 10.1126/Scisignal.2002734  0.417
2012 Lopes R, Verhey van Wijk N, Neves G, Pachnis V. Transcription factor LIM homeobox 7 (Lhx7) maintains subtype identity of cholinergic interneurons in the mammalian striatum. Proceedings of the National Academy of Sciences of the United States of America. 109: 3119-24. PMID 22315402 DOI: 10.1073/Pnas.1109251109  0.467
2012 Sasselli V, Pachnis V, Burns AJ. The enteric nervous system. Developmental Biology. 366: 64-73. PMID 22290331 DOI: 10.1016/j.ydbio.2012.01.012  0.469
2012 Vidaki M, Tivodar S, Doulgeraki K, Tybulewicz V, Kessaris N, Pachnis V, Karagogeos D. Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex. Cerebral Cortex (New York, N.Y. : 1991). 22: 680-92. PMID 21690261 DOI: 10.1093/Cercor/Bhr145  0.367
2011 Laranjeira C, Sandgren K, Kessaris N, Richardson W, Potocnik A, Vanden Berghe P, Pachnis V. Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury. The Journal of Clinical Investigation. 121: 3412-24. PMID 21865647 DOI: 10.1172/JCI58200  0.475
2011 Spella M, Kyrousi C, Kritikou E, Stathopoulou A, Guillemot F, Kioussis D, Pachnis V, Lygerou Z, Taraviras S. Geminin regulates cortical progenitor proliferation and differentiation. Stem Cells (Dayton, Ohio). 29: 1269-82. PMID 21681860 DOI: 10.1002/stem.678  0.461
2011 Heanue TA, Pachnis V. Prospective identification and isolation of enteric nervous system progenitors using Sox2. Stem Cells (Dayton, Ohio). 29: 128-40. PMID 21280162 DOI: 10.1002/stem.557  0.447
2010 Karamitros D, Kotantaki P, Lygerou Z, Veiga-Fernandes H, Pachnis V, Kioussis D, Taraviras S. Life without geminin. Cell Cycle (Georgetown, Tex.). 9: 3181-5. PMID 20697201 DOI: 10.4161/cc.9.16.12554  0.43
2010 Karamitros D, Kotantaki P, Lygerou Z, Veiga-Fernandes H, Pachnis V, Kioussis D, Taraviras S. Differential geminin requirement for proliferation of thymocytes and mature T cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 2432-41. PMID 20107189 DOI: 10.4049/jimmunol.0901983  0.372
2010 Lopes R, Pachnis V. [P1.76]: LHX7 is required in mouse striatal cholinergic interneurons to maintain neuronal subtype identity International Journal of Developmental Neuroscience. 28: 680-680. DOI: 10.1016/j.ijdevneu.2010.07.116  0.38
2009 Fragkouli A, van Wijk NV, Lopes R, Kessaris N, Pachnis V. LIM homeodomain transcription factor-dependent specification of bipotential MGE progenitors into cholinergic and GABAergic striatal interneurons. Development (Cambridge, England). 136: 3841-51. PMID 19855026 DOI: 10.1242/dev.038083  0.443
2009 Kioussis D, Pachnis V. Immune and nervous systems: more than just a superficial similarity? Immunity. 31: 705-10. PMID 19836266 DOI: 10.1016/j.immuni.2009.09.009  0.303
2009 Laranjeira C, Pachnis V. Enteric nervous system development: Recent progress and future challenges. Autonomic Neuroscience : Basic & Clinical. 151: 61-9. PMID 19783483 DOI: 10.1016/j.autneu.2009.09.001  0.341
2009 Batista-Brito R, Rossignol E, Hjerling-Leffler J, Denaxa M, Wegner M, Lefebvre V, Pachnis V, Fishell G. The cell-intrinsic requirement of Sox6 for cortical interneuron development. Neuron. 63: 466-81. PMID 19709629 DOI: 10.1016/J.Neuron.2009.08.005  0.447
2009 Denaxa M, Sharpe PT, Pachnis V. The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition. Developmental Biology. 333: 324-36. PMID 19591819 DOI: 10.1016/j.ydbio.2009.07.001  0.408
2009 Skuntz S, Mankoo B, Nguyen MT, Hustert E, Nakayama A, Tournier-Lasserve E, Wright CV, Pachnis V, Bharti K, Arnheiter H. Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton. Developmental Biology. 332: 383-95. PMID 19520072 DOI: 10.1016/j.ydbio.2009.06.006  0.382
2009 Burns AJ, Pachnis V. Development of the enteric nervous system: bringing together cells, signals and genes. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 21: 100-2. PMID 19215587 DOI: 10.1111/j.1365-2982.2008.01255.x  0.482
2009 Fragkouli A, Pachnis V, Stylianopoulou F. Sex differences in water maze performance and cortical neurotrophin levels of LHX7 null mutant mice. Neuroscience. 158: 1224-33. PMID 19095044 DOI: 10.1016/j.neuroscience.2008.11.026  0.336
2009 Laranjeira C, Kessaris N, Pachnis V. 17-P015 Temporal regulation of neurogenesis in the enteric nervous system Mechanisms of Development. 126: S275. DOI: 10.1016/j.mod.2009.06.736  0.302
2009 Heanue T, Pachnis V. 14-P001 SOX2 expression provides a means to identify and isolate ENS progenitors Mechanisms of Development. 126: S239. DOI: 10.1016/j.mod.2009.06.620  0.303
2009 Lopes R, Tye A, Evans S, Lovell-Badge R, Pachnis V. 12-P010 Role of LIM homedomain transcription factors LHX7 and ISL1 in the specification of mouse basal forebrain cholinergic neurons Mechanisms of Development. 126: S192. DOI: 10.1016/J.Mod.2009.06.464  0.451
2008 Bogni S, Trainor P, Natarajan D, Krumlauf R, Pachnis V. Non-cell-autonomous effects of Ret deletion in early enteric neurogenesis. Development (Cambridge, England). 135: 3007-11. PMID 18684739 DOI: 10.1242/Dev.025163  0.429
2008 Heanue TA, Pachnis V. Ret isoform function and marker gene expression in the enteric nervous system is conserved across diverse vertebrate species. Mechanisms of Development. 125: 687-99. PMID 18565740 DOI: 10.1016/j.mod.2008.04.006  0.478
2008 Foster K, Sheridan J, Veiga-Fernandes H, Roderick K, Pachnis V, Adams R, Blackburn C, Kioussis D, Coles M. Contribution of neural crest-derived cells in the embryonic and adult thymus. Journal of Immunology (Baltimore, Md. : 1950). 180: 3183-9. PMID 18292542 DOI: 10.4049/Jimmunol.180.5.3183  0.401
2007 Fogarty M, Grist M, Gelman D, Marín O, Pachnis V, Kessaris N. Spatial genetic patterning of the embryonic neuroepithelium generates GABAergic interneuron diversity in the adult cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10935-46. PMID 17928435 DOI: 10.1523/Jneurosci.1629-07.2007  0.385
2007 Heanue TA, Pachnis V. Enteric nervous system development and Hirschsprung's disease: advances in genetic and stem cell studies. Nature Reviews. Neuroscience. 8: 466-79. PMID 17514199 DOI: 10.1038/nrn2137  0.338
2007 Liodis P, Denaxa M, Grigoriou M, Akufo-Addo C, Yanagawa Y, Pachnis V. Lhx6 activity is required for the normal migration and specification of cortical interneuron subtypes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3078-89. PMID 17376969 DOI: 10.1523/Jneurosci.3055-06.2007  0.385
2007 Veiga-Fernandes H, Coles MC, Foster KE, Patel A, Williams A, Natarajan D, Barlow A, Pachnis V, Kioussis D. Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis. Nature. 446: 547-51. PMID 17322904 DOI: 10.1038/nature05597  0.392
2007 Heanue TA, Pachnis V. WITHDRAWN: Expression profiling the developing mammalian enteric nervous system identifies novel markers and candidate Hirschsprung disease genes Developmental Biology. 306: 420. DOI: 10.1016/J.Ydbio.2007.03.307  0.356
2006 Asai N, Fukuda T, Wu Z, Enomoto A, Pachnis V, Takahashi M, Costantini F. Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells. Development (Cambridge, England). 133: 4507-16. PMID 17050626 DOI: 10.1242/Dev.02616  0.365
2006 Stanchina L, Baral V, Robert F, Pingault V, Lemort N, Pachnis V, Goossens M, Bondurand N. Interactions between Sox10, Edn3 and Ednrb during enteric nervous system and melanocyte development. Developmental Biology. 295: 232-49. PMID 16650841 DOI: 10.1016/j.ydbio.2006.03.031  0.447
2006 Heanue TA, Pachnis V. Expression profiling the developing mammalian enteric nervous system identifies marker and candidate Hirschsprung disease genes. Proceedings of the National Academy of Sciences of the United States of America. 103: 6919-24. PMID 16632597 DOI: 10.1016/j.ydbio.2007.03.653  0.407
2006 Bondurand N, Natarajan D, Barlow A, Thapar N, Pachnis V. Maintenance of mammalian enteric nervous system progenitors by SOX10 and endothelin 3 signalling. Development (Cambridge, England). 133: 2075-86. PMID 16624853 DOI: 10.1242/dev.02375  0.453
2006 Cassiman D, Barlow A, Vander Borght S, Libbrecht L, Pachnis V. Hepatic stellate cells do not derive from the neural crest. Journal of Hepatology. 44: 1098-104. PMID 16458991 DOI: 10.1016/j.jhep.2005.09.023  0.401
2006 Fragkouli A, Stamatakis A, Zographos E, Pachnis V, Stylianopoulou F. Sexually dimorphic effects of the Lhx7 null mutation on forebrain cholinergic function. Neuroscience. 137: 1153-64. PMID 16338089 DOI: 10.1016/j.neuroscience.2005.10.037  0.375
2005 Viemari JC, Maussion G, Bévengut M, Burnet H, Pequignot JM, Népote V, Pachnis V, Simonneau M, Hilaire G. Ret deficiency in mice impairs the development of A5 and A6 neurons and the functional maturation of the respiratory rhythm. The European Journal of Neuroscience. 22: 2403-12. PMID 16307583 DOI: 10.1111/J.1460-9568.2005.04441.X  0.348
2005 Jukkola T, Trokovic R, Maj P, Lamberg A, Mankoo B, Pachnis V, Savilahti H, Partanen J. Meox1Cre: a mouse line expressing Cre recombinase in somitic mesoderm. Genesis (New York, N.Y. : 2000). 43: 148-53. PMID 16267823 DOI: 10.1002/Gene.20163  0.39
2005 Wong A, Bogni S, Kotka P, de Graaff E, D'Agati V, Costantini F, Pachnis V. Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform. Molecular and Cellular Biology. 25: 9661-73. PMID 16227613 DOI: 10.1128/Mcb.25.21.9661-9673.2005  0.401
2005 Fragkouli A, Hearn C, Errington M, Cooke S, Grigoriou M, Bliss T, Stylianopoulou F, Pachnis V. Loss of forebrain cholinergic neurons and impairment in spatial learning and memory in LHX7-deficient mice. The European Journal of Neuroscience. 21: 2923-38. PMID 15978004 DOI: 10.1111/j.1460-9568.2005.04141.x  0.413
2004 Fu M, Lui VC, Sham MH, Pachnis V, Tam PK. Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest cells in gut. The Journal of Cell Biology. 166: 673-84. PMID 15337776 DOI: 10.1083/jcb.200401077  0.466
2004 Xouri G, Lygerou Z, Nishitani H, Pachnis V, Nurse P, Taraviras S. Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines. European Journal of Biochemistry / Febs. 271: 3368-78. PMID 15291814 DOI: 10.1111/J.1432-1033.2004.04271.X  0.35
2004 Kapur RP, Gershon MD, Milla PJ, Pachnis V. The influence of Hox genes and three intercellular signalling pathways on enteric neuromuscular development. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 16: 8-13. PMID 15065997 DOI: 10.1111/J.1743-3150.2004.00467.X  0.388
2003 Barlow A, de Graaff E, Pachnis V. Enteric nervous system progenitors are coordinately controlled by the G protein-coupled receptor EDNRB and the receptor tyrosine kinase RET. Neuron. 40: 905-16. PMID 14659090 DOI: 10.1016/S0896-6273(03)00730-X  0.339
2003 Bondurand N, Natarajan D, Thapar N, Atkins C, Pachnis V. Neuron and glia generating progenitors of the mammalian enteric nervous system isolated from foetal and postnatal gut cultures. Development (Cambridge, England). 130: 6387-400. PMID 14623827 DOI: 10.1242/dev.00857  0.434
2003 Mankoo BS, Skuntz S, Harrigan I, Grigorieva E, Candia A, Wright CV, Arnheiter H, Pachnis V. The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites. Development (Cambridge, England). 130: 4655-64. PMID 12925591 DOI: 10.1242/dev.00687  0.382
2003 Holmes FE, Bacon A, Pope RJ, Vanderplank PA, Kerr NC, Sukumaran M, Pachnis V, Wynick D. Transgenic overexpression of galanin in the dorsal root ganglia modulates pain-related behavior. Proceedings of the National Academy of Sciences of the United States of America. 100: 6180-5. PMID 12721371 DOI: 10.1073/Pnas.0937087100  0.714
2002 Natarajan D, Marcos-Gutierrez C, Pachnis V, de Graaff E. Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis. Development (Cambridge, England). 129: 5151-60. PMID 12399307  0.347
2002 Aizenfisz S, Dauger S, Durand E, Vardon G, Levacher B, Simonneau M, Pachnis V, Gaultier C, Gallego J. Ventilatory responses to hypercapnia and hypoxia in heterozygous c-ret newborn mice. Respiratory Physiology & Neurobiology. 131: 213-22. PMID 12126922 DOI: 10.1016/S1569-9048(02)00031-9  0.338
2001 Sukumaran M, Waxman SG, Wood JN, Pachnis V. Flanking regulatory sequences of the locus encoding the murine GDNF receptor, c-ret, directs lac Z (beta-galactosidase) expression in developing somatosensory system. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 222: 389-402. PMID 11747074 DOI: 10.1002/dvdy.1192  0.416
2001 de Graaff E, Srinivas S, Kilkenny C, D'Agati V, Mankoo BS, Costantini F, Pachnis V. Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis. Genes & Development. 15: 2433-44. PMID 11562352 DOI: 10.1101/Gad.205001  0.384
2001 Stamataki D, Kastrinaki M, Mankoo BS, Pachnis V, Karagogeos D. Homeodomain proteins Mox1 and Mox2 associate with Pax1 and Pax3 transcription factors. Febs Letters. 499: 274-8. PMID 11423130 DOI: 10.1016/S0014-5793(01)02556-X  0.315
2000 Holmes FE, Mahoney S, King VR, Bacon A, Kerr NC, Pachnis V, Curtis R, Priestley JV, Wynick D. Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity. Proceedings of the National Academy of Sciences of the United States of America. 97: 11563-8. PMID 11016970 DOI: 10.1073/Pnas.210221897  0.737
2000 Parnavelas JG, Anderson SA, Lavdas AA, Grigoriou M, Pachnis V, Rubenstein JL. The contribution of the ganglionic eminence to the neuronal cell types of the cerebral cortex. Novartis Foundation Symposium. 228: 129-39; discussion 1. PMID 10929320 DOI: 10.1002/0470846631.Ch10  0.406
1999 Lavdas AA, Grigoriou M, Pachnis V, Parnavelas JG. The medial ganglionic eminence gives rise to a population of early neurons in the developing cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 7881-8. PMID 10479690 DOI: 10.1523/Jneurosci.19-18-07881.1999  0.437
1999 Mankoo BS, Collins NS, Ashby P, Grigorieva E, Pevny LH, Candia A, Wright CV, Rigby PW, Pachnis V. Mox2 is a component of the genetic hierarchy controlling limb muscle development. Nature. 400: 69-73. PMID 10403250 DOI: 10.1038/21892  0.323
1999 Taraviras S, Pachnis V. Development of the mammalian enteric nervous system. Current Opinion in Genetics & Development. 9: 321-7. PMID 10377293 DOI: 10.1016/S0959-437X(99)80048-3  0.374
1999 Taraviras S, Marcos-Gutierrez CV, Durbec P, Jani H, Grigoriou M, Sukumaran M, Wang LC, Hynes M, Raisman G, Pachnis V. Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system. Development (Cambridge, England). 126: 2785-97. PMID 10331988  0.344
1999 Natarajan D, Grigoriou M, Marcos-Gutierrez CV, Atkins C, Pachnis V. Multipotential progenitors of the mammalian enteric nervous system capable of colonising aganglionic bowel in organ culture. Development (Cambridge, England). 126: 157-68. PMID 9834195  0.316
1998 Wynick D, Small CJ, Bloom SR, Pachnis V. Targeted disruption of the murine galanin gene. Annals of the New York Academy of Sciences. 863: 22-47. PMID 9928157 DOI: 10.1111/J.1749-6632.1998.Tb10681.X  0.671
1998 Attié-Bitach T, Abitbol M, Gérard M, Delezoide AL, Augé J, Pelet A, Amiel J, Pachnis V, Munnich A, Lyonnet S, Vekemans M. Expression of the RET proto-oncogene in human embryos. American Journal of Medical Genetics. 80: 481-6. PMID 9880212 DOI: 10.1002/(Sici)1096-8628(19981228)80:5<481::Aid-Ajmg8>3.0.Co;2-6  0.41
1998 Wynick D, Small CJ, Bacon A, Holmes FE, Norman M, Ormandy CJ, Kilic E, Kerr NC, Ghatei M, Talamantes F, Bloom SR, Pachnis V. Galanin regulates prolactin release and lactotroph proliferation. Proceedings of the National Academy of Sciences of the United States of America. 95: 12671-6. PMID 9770544 DOI: 10.1073/Pnas.95.21.12671  0.709
1998 Pachnis V, Durbec P, Taraviras S, Grigoriou M, Natarajan D. III. Role Of the RET signal transduction pathway in development of the mammalian enteric nervous system. The American Journal of Physiology. 275: G183-6. PMID 9688643 DOI: 10.1152/Ajpgi.1998.275.2.G183  0.39
1997 Burton MD, Kawashima A, Brayer JA, Kazemi H, Shannon DC, Schuchardt A, Costantini F, Pachnis V, Kinane TB. RET proto-oncogene is important for the development of respiratory CO2 sensitivity. Journal of the Autonomic Nervous System. 63: 137-43. PMID 9138245 DOI: 10.1016/S0165-1838(97)00002-7  0.332
1997 Marcos-Gutiérrez CV, Wilson SW, Holder N, Pachnis V. The zebrafish homologue of the ret receptor and its pattern of expression during embryogenesis. Oncogene. 14: 879-89. PMID 9050987 DOI: 10.1038/Sj.Onc.1201048  0.456
1996 Rothman TP, Chen J, Howard MJ, Costantini F, Schuchardt A, Pachnis V, Gershon MD. Increased expression of laminin-1 and collagen (IV) subunits in the aganglionic bowel of ls/ls, but not c-ret -/- mice. Developmental Biology. 178: 498-513. PMID 8812145 DOI: 10.1006/Dbio.1996.0234  0.354
1996 Durbec P, Marcos-Gutierrez CV, Kilkenny C, Grigoriou M, Wartiowaara K, Suvanto P, Smith D, Ponder B, Costantini F, Saarma M, Sariola H, Pachnis V. GDNF signalling through the Ret receptor tyrosine kinase Nature. 381: 789-793. PMID 8657282 DOI: 10.1038/381789A0  0.41
1996 Trupp M, Arenas E, Fainzilber M, Nilsson AS, Sieber BA, Grigoriou M, Kilkenny C, Salazar-Grueso E, Pachnis V, Arumäe U. Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature. 381: 785-9. PMID 8657281 DOI: 10.1038/381785A0  0.399
1996 Durbec PL, Larsson-Blomberg LB, Schuchardt A, Costantini F, Pachnis V. Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts. Development (Cambridge, England). 122: 349-58. PMID 8565847  0.322
1995 Schuchardt A, D'Agati V, Larsson-Blomberg L, Costantini F, Pachnis V. RET-deficient mice: an animal model for Hirschsprung's disease and renal agenesis. Journal of Internal Medicine. 238: 327-32. PMID 7595168 DOI: 10.1111/J.1365-2796.1995.Tb01206.X  0.349
1994 Schuchardt A, D'Agati V, Larsson-Blomberg L, Costantini F, Pachnis V. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature. 367: 380-3. PMID 8114940 DOI: 10.1038/367380A0  0.419
1988 Pachnis V, Brannan CI, Tilghman SM. The structure and expression of a novel gene activated in early mouse embryogenesis. The Embo Journal. 7: 673-81. PMID 3396539 DOI: 10.1002/J.1460-2075.1988.Tb02862.X  0.328
1988 Yoo-Warren H, Pachnis V, Ingram RS, Tilghman SM. Two regulatory domains flank the mouse H19 gene. Molecular and Cellular Biology. 8: 4707-15. PMID 2463463 DOI: 10.1128/MCB.8.11.4707  0.335
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