Jean-Pierre Changeux - Related publications

Institut Pasteur, Paris, Paris, France 
Molecular Neurobiology
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Papke RL, Brunzell DH, De Biasi M. Cholinergic Receptors and Addiction. Current Topics in Behavioral Neurosciences. PMID 32451953 DOI: 10.1007/7854_2020_139   
2020 Ghimire M, Cai R, Ling L, Hackett TA, Caspary DM. Nicotinic Receptor Subunit Distribution in Auditory Cortex: Impact of Aging on Receptor Number and Function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32541068 DOI: 10.1523/JNEUROSCI.0093-20.2020   
2020 Becerra GP, Rojas-Rodríguez F, Ramírez D, Loaiza AE, Tobar-Tosse F, Mejía SM, González J. Structural and functional computational analysis of nicotine analogs as potential neuroprotective compounds in Parkinson disease. Computational Biology and Chemistry. 86: 107266. PMID 32388154 DOI: 10.1016/j.compbiolchem.2020.107266   
2020 Marcovich I, Moglie MJ, Carpaneto Freixas AE, Trigila AP, Franchini LF, Plazas PV, Lipovsek M, Elgoyhen AB. Distinct Evolutionary Trajectories of Neuronal and Hair Cell Nicotinic Acetylcholine Receptors. Molecular Biology and Evolution. 37: 1070-1089. PMID 31821508 DOI: 10.1093/molbev/msz290   
2020 Johnson K, Yin J, In JG, Kulkarni S, Pasricha P, Tse M, Donowitz M. Cholinergic-induced anion secretion in murine jejunal enteroids involves synergy between muscarinic and nicotinic pathways. American Journal of Physiology. Cell Physiology. PMID 32551856 DOI: 10.1152/ajpcell.00179.2020   
2020 Muldoon PP, Akinola LS, Schlosburg JE, Lichtman AH, Sim-Selley LJ, Mahadevan A, Cravatt BF, Damaj MI. Inhibition of monoacylglycerol lipase reduces nicotine reward in the conditioned place preference test in male mice. Neuropharmacology. 108170. PMID 32479813 DOI: 10.1016/j.neuropharm.2020.108170   
2020 Bertrand D, Wallace TL. A Review of the Cholinergic System and Therapeutic Approaches to Treat Brain Disorders. Current Topics in Behavioral Neurosciences. PMID 32451956 DOI: 10.1007/7854_2020_141   
2020 McHugh M, Williams P, Verma S, Powell-Coffman JA, Robertson AP, Martin RJ. Cholinergic receptors on intestine cells of Ascaris suum and activation of nAChRs by levamisole. International Journal For Parasitology. Drugs and Drug Resistance. 13: 38-50. PMID 32470835 DOI: 10.1016/j.ijpddr.2020.04.002   
2020 Tsetlin VI. Acetylcholine and Acetylcholine Receptors: Textbook Knowledge and New Data. Biomolecules. 10. PMID 32503306 DOI: 10.3390/biom10060852   
2020 Fujii N, McGarr GW, Ghassa R, Schmidt MD, McCormick JJ, Nishiyasu T, Kenny GP. Sex-differences in cholinergic, nicotinic, and β-adrenergic cutaneous vasodilation: Roles of nitric oxide synthase, cyclooxygenase, and K channels. Microvascular Research. 131: 104030. PMID 32531353 DOI: 10.1016/j.mvr.2020.104030   
2020 Wang X, Bell IM, Uslaner JM. Activators of α7 nAChR as Potential Therapeutics for Cognitive Impairment. Current Topics in Behavioral Neurosciences. PMID 32451955 DOI: 10.1007/7854_2020_140   
2020 Antonio-Tolentino K, Hopkins CR. Selective α7 nicotinic receptor agonists and positive allosteric modulators for the treatment of schizophrenia - a review. Expert Opinion On Investigational Drugs. 1-7. PMID 32396418 DOI: 10.1080/13543784.2020.1764938   
2020 Patel RN, Richards DP, Duce IR, Birkett MA, Sattelle DB, Mellor IR. Actions on mammalian and insect nicotinic acetylcholine receptors of harmonine-containing alkaloid extracts from the harlequin ladybird Harmonia axyridis. Pesticide Biochemistry and Physiology. 166: 104561. PMID 32448416 DOI: 10.1016/j.pestbp.2020.104561   
2020 Prevost MS, Bouchenaki H, Barilone N, Gielen M, Corringer PJ. Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors. Cellular and Molecular Life Sciences : Cmls. PMID 32472188 DOI: 10.1007/s00018-020-03558-z   
2020 Ihara M, Furutani S, Shigetou S, Shimada S, Niki K, Komori Y, Kamiya M, Koizumi W, Magara L, Hikida M, Noguchi A, Okuhara D, Yoshinari Y, Kondo S, Tanimoto H, et al. Cofactor-enabled functional expression of fruit fly, honeybee, and bumblebee nicotinic receptors reveals picomolar neonicotinoid actions. Proceedings of the National Academy of Sciences of the United States of America. PMID 32611810 DOI: 10.1073/pnas.2003667117   
2020 Eom S, Kim C, Yeom HD, Lee J, Lee S, Baek YB, Na J, Park SI, Kim GY, Lee CM, Lee JH. Molecular Regulation of α3β4 Nicotinic Acetylcholine Receptors by Lupeol in Cardiovascular System. International Journal of Molecular Sciences. 21. PMID 32570692 DOI: 10.3390/ijms21124329   
2020 Gillet C, Kurth S, Kuenzel T. Muscarinic modulation of M and h currents in gerbil spherical bushy cells. Plos One. 15: e0226954. PMID 31940388 DOI: 10.1371/journal.pone.0226954   
2020 Butler K, Le Foll B. Novel therapeutic and drug development strategies for tobacco use disorder: endocannabinoid modulation. Expert Opinion On Drug Discovery. 1-16. PMID 32425077 DOI: 10.1080/17460441.2020.1767581   
2020 Zheng N, Christensen S, Blakely A, Dowell C, Purushottam L, McIntosh JM, Chou DH. Development of Conformationally Constrained α-RgIA Analogues as Stable Peptide Antagonists of Human α9α10 Nicotinic Acetylcholine Receptors. Journal of Medicinal Chemistry. PMID 32597184 DOI: 10.1021/acs.jmedchem.0c00613   
2020 Liu JYH, Du P, Rudd JA. Acetylcholine Exerts Inhibitory and Excitatory Actions on Mouse Ileal Pacemaker Activity: The Role of Muscarinic versus Nicotinic Receptors. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 32475128 DOI: 10.1152/ajpgi.00003.2020   
2020 Homem RA, Buttery B, Richardson EE, Tan Y, Field LM, Williamson MS, Davies TGE. Evolutionary trade-offs of insecticide resistance - the fitness costs associated with target-site mutations in the nAChR of Drosophila melanogaster. Molecular Ecology. PMID 32510730 DOI: 10.1111/mec.15503   
2020 Pandey T, Smita SS, Mishra A, Sammi SR, Pandey R. Swertiamarin, a secoiridoid glycoside modulates nAChR and AChE activity. Experimental Gerontology. 111010. PMID 32590127 DOI: 10.1016/j.exger.2020.111010   
2020 Olander ER, Janzen D, Villmann C, Jensen AA. Comparison of biophysical properties of α1β2 and α3β2 GABAA receptors in whole-cell patch-clamp electrophysiological recordings. Plos One. 15: e0234080. PMID 32479525 DOI: 10.1371/journal.pone.0234080   
2020 Salazar H, Mischke S, Plested AJR. Measurements of the Timescale and Conformational Space of AMPA Receptor Desensitization. Biophysical Journal. PMID 32559412 DOI: 10.1016/j.bpj.2020.05.029   
2020 Lü S, Jiang M, Tian X, Hong S, Zhang J, Zhang Y. Characterization of an A-Type Muscarinic Acetylcholine Receptor and Its Possible Non-neuronal Role in the Oriental Armyworm, Walker (Lepidoptera: Noctuidae). Frontiers in Physiology. 11: 400. PMID 32425811 DOI: 10.3389/fphys.2020.00400   
2020 Chou TH, Tajima N, Romero-Hernandez A, Furukawa H. Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell. PMID 32610085 DOI: 10.1016/j.cell.2020.05.052   
2020 Perszyk RE, Myers SJ, Yuan H, Gibb AJ, Furukawa H, Sobolevsky AI, Traynelis SF. Hodgkin-huxley-katz prize lecture: genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif. The Journal of Physiology. PMID 32468591 DOI: 10.1113/JP278086   
2020 Bolchi C, Bavo F, Appiani R, Roda G, Pallavicini M. 1,4-Benzodioxane, an evergreen, versatile scaffold in medicinal chemistry: A review of its recent applications in drug design. European Journal of Medicinal Chemistry. 200: 112419. PMID 32502862 DOI: 10.1016/j.ejmech.2020.112419   
2020 Datta S, Singh S, Govindarajan R. Retrospective Analysis of Eculizumab in Patients with Acetylcholine Receptor Antibody-Negative Myasthenia Gravis: A Case Series. Journal of Neuromuscular Diseases. PMID 32444555 DOI: 10.3233/JND-190464   
2020 Wydra K, Gawliński D, Gawlińska K, Frankowska M, Borroto-Escuela DO, Fuxe K, Filip M. Adenosine AReceptors in Substance Use Disorders: A Focus on Cocaine. Cells. 9. PMID 32492952 DOI: 10.3390/cells9061372   
2020 Albazli K, Kaminski HJ, Howard JF. Complement Inhibitor Therapy for Myasthenia Gravis. Frontiers in Immunology. 11: 917. PMID 32582144 DOI: 10.3389/fimmu.2020.00917   
2020 Sato K. Why is prepulse inhibition disrupted in schizophrenia? Medical Hypotheses. 143: 109901. PMID 32502900 DOI: 10.1016/j.mehy.2020.109901   
2020 Breitinger U, Breitinger HG. Modulators of the inhibitory glycine receptor. Acs Chemical Neuroscience. PMID 32391682 DOI: 10.1021/acschemneuro.0c00054   
2020 Soto P, Gaete PS, Fuentes C, Lozano B, Naulin PA, Figueroa XF, Barrera NP. Function of P2X4 Receptors Is Directly Modulated by a 1:1 Stoichiometric Interaction With 5-HTA Receptors. Frontiers in Cellular Neuroscience. 14: 106. PMID 32431598 DOI: 10.3389/fncel.2020.00106   
2020 Fichtner ML, Jiang R, Bourke A, Nowak RJ, O'Connor KC. Autoimmune Pathology in Myasthenia Gravis Disease Subtypes Is Governed by Divergent Mechanisms of Immunopathology. Frontiers in Immunology. 11: 776. PMID 32547535 DOI: 10.3389/fimmu.2020.00776   
2020 Sun HS, Yang QR, Bai YY, Hu NW, Liu DX, Qin CY. Gene testing for osteonecrosis of the femoral head in systemic lupus erythematosus using targeted next-generation sequencing: A pilot study. World Journal of Clinical Cases. 8: 2530-2541. PMID 32607330 DOI: 10.12998/wjcc.v8.i12.2530   
2020 Sadanandan SM, Kreko-Pierce T, Khatri SN, Pugh JR. Cannabinoid type 2 receptors inhibit GABAA receptor-mediated currents in cerebellar Purkinje cells of juvenile mice. Plos One. 15: e0233020. PMID 32437355 DOI: 10.1371/journal.pone.0233020   
2020 Brimson JM, Akula KK, Abbas H, Ferry DR, Kulkarni SK, Russell ST, Tisdale MJ, Tencomnao T, Safrany ST. Simple ammonium salts acting on sigma-1 receptors yield potential treatments for cancer and depression. Scientific Reports. 10: 9251. PMID 32514120 DOI: 10.1038/s41598-020-65849-6   
2020 Yuan S, Roos PM, Larsson SC. IL-1 Receptor Antagonist, IL-2 Receptor Alpha Subunit and Amyotrophic Lateral Sclerosis. European Journal of Neurology. PMID 32441415 DOI: 10.1111/ene.14338   
2020 Ladurner A, Linder T, Wang L, Hiebl V, Schuster D, Schnürch M, Mihovilovic MD, Atanasov AG, Dirsch VM. Characterization of a Structural Leoligin Analog as Farnesoid X Receptor Agonist and Modulator of Cholesterol Transport. Planta Medica. PMID 32485752 DOI: 10.1055/a-1171-8357   
2020 Fischer JP, Els-Heindl S, Beck-Sickinger AG. Adrenomedullin - Current Perspective on a Peptide Hormone with Significant Therapeutic Potential. Peptides. 170347. PMID 32569606 DOI: 10.1016/j.peptides.2020.170347   
2020 Luo S, Hou Y, Zhang Y, Ma T, Shao W, Xiao C. Adenosine A Receptor Agonist PSB-0777 Modulates Synaptic Proteins and AMPA Receptor Expression in A Dose- and Time-Dependent Manner in Rat Primary Cortical Neurons. Biological & Pharmaceutical Bulletin. PMID 32448843 DOI: 10.1248/bpb.b19-01007   
2020 Riad A, Lengyel-Zhand Z, Zeng C, Weng CC, Lee VM, Trojanowski JQ, Mach RH. The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor Complex Are Responsible for the Cellular Uptake of Aβ42 and Its Protein Aggregates. Molecular Neurobiology. PMID 32572762 DOI: 10.1007/s12035-020-01988-1   
2020 Lindemann M, Moldovan RP, Hinz S, Deuther-Conrad W, Gündel D, Dukic-Stefanovic S, Toussaint M, Teodoro R, Juhl C, Steinbach J, Brust P, Müller CE, Wenzel B. Development of a Radiofluorinated Adenosine A Receptor Antagonist as Potential Ligand for PET Imaging. International Journal of Molecular Sciences. 21. PMID 32366046 DOI: 10.3390/ijms21093197   
2020 Magno AL, Leatherbarrow KM, Brown SJ, Wilson SG, Walsh JP, Ward BK. Functional Analysis of Calcium-Sensing Receptor Variants Identified in Families Provisionally Diagnosed with Familial Hypocalciuric Hypercalcaemia. Calcified Tissue International. PMID 32638038 DOI: 10.1007/s00223-020-00715-1   
2020 Liu X, Kaindl J, Korczynska M, Stößel A, Dengler D, Stanek M, Hübner H, Clark MJ, Mahoney J, Matt RA, Xu X, Hirata K, Shoichet BK, Sunahara RK, Kobilka BK, et al. An allosteric modulator binds to a conformational hub in the β adrenergic receptor. Nature Chemical Biology. PMID 32483378 DOI: 10.1038/s41589-020-0549-2   
2020 Neumann A, Engel V, Mahardhika AB, Schoeder CT, Namasivayam V, Kieć-Kononowicz K, Müller CE. Computational Investigations on the Binding Mode of Ligands for the Cannabinoid-Activated G Protein-Coupled Receptor GPR18. Biomolecules. 10. PMID 32365486 DOI: 10.3390/biom10050686   
2020 Grimes L, Griffiths J, Pasqualetto G, Brancale A, Kemp PJ, Young MT, van der Goes van Naters W. Drosophila taste neurons as an agonist-screening platform for P2X receptors. Scientific Reports. 10: 8292. PMID 32427920 DOI: 10.1038/s41598-020-65169-9   
2020 Burada AP, Vinnakota R, Kumar J. The Architecture of GluD2 Ionotropic Delta Glutamate Receptor Elucidated by cryo-EM. Journal of Structural Biology. 107546. PMID 32512155 DOI: 10.1016/j.jsb.2020.107546   
2020 Rauschenberger V, Wardenburg NV, Schaefer N, Ogino K, Hirata H, Lillesaar C, Kluck CJ, Meinck HM, Borrmann M, Weishaupt A, Doppler K, Wickel J, Geis C, Sommer C, Villmann C. GlyR autoantibodies impair receptor function and induce motor dysfunction. Annals of Neurology. PMID 32588476 DOI: 10.1002/ana.25832