Year |
Citation |
Score |
2019 |
Strainic MG, Pohlmann E, Valley CC, Sammeta A, Hussain W, Lidke DS, Medof ME. RTK signaling requires C3ar1/C5ar1 and IL-6R joint signaling to repress dominant PTEN, SOCS1/3 and PHLPP restraint. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 31908021 DOI: 10.1096/Fj.201900677R |
0.354 |
|
2018 |
Brandsma AM, Schwartz SL, Wester MJ, Valley CC, Blezer GLA, Vidarsson G, Lidke KA, Ten Broeke T, Lidke DS, Leusen JHW. Mechanisms of inside-out signaling of the high-affinity IgG receptor FcγRI. Science Signaling. 11. PMID 30042128 DOI: 10.1126/Scisignal.Aaq0891 |
0.423 |
|
2017 |
Freed DM, Bessman NJ, Kiyatkin A, Salazar-Cavazos E, Byrne PO, Moore JO, Valley CC, Ferguson KM, Leahy DJ, Lidke DS, Lemmon MA. EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics. Cell. PMID 28988771 DOI: 10.1016/J.Cell.2017.09.017 |
0.494 |
|
2017 |
Valley CC, Lewis AK, Sachs JN. Piecing it together: Unraveling the elusive structure-function relationship in single-pass membrane receptors. Biochimica Et Biophysica Acta. PMID 28089689 DOI: 10.1016/J.Bbamem.2017.01.016 |
0.782 |
|
2016 |
Lewis AK, Valley CC, Peery SL, Brummel B, Braun AR, Karim C, Sachs JN. Death Receptor 5 Networks Require Membrane Cholesterol for Proper Structure and Function. Journal of Molecular Biology. PMID 27720987 DOI: 10.1016/J.Jmb.2016.10.001 |
0.794 |
|
2016 |
Lewis AK, Dunleavy KM, Senkow TL, Her C, Horn BT, Jersett MA, Mahling R, McCarthy MR, Perell GT, Valley CC, Karim CB, Gao J, Pomerantz WC, Thomas DD, Cembran A, et al. Oxidation increases the strength of the methionine-aromatic interaction. Nature Chemical Biology. PMID 27547920 DOI: 10.1038/Nchembio.2159 |
0.71 |
|
2015 |
Valley CC, Arndt-Jovin DJ, Karedla N, Steinkamp MP, Chizhik AI, Hlavacek WS, Wilson BS, Lidke KA, Lidke DS. Enhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancer. Molecular Biology of the Cell. 26: 4087-99. PMID 26337388 DOI: 10.1091/Mbc.E15-05-0269 |
0.428 |
|
2015 |
Valley CC, Arndt-Jovin DJ, Jovin TM, Steinkamp MP, Chizhik AI, Karedla N, Hlavacek WS, Wilson BS, Lidke KA, Lidke DS. Inside-Out Signaling of Oncogenic EGFR Mutants Promotes Ligand-Independent Dimerization Biophysical Journal. 108: 351a. DOI: 10.1016/J.Bpj.2014.11.1921 |
0.493 |
|
2014 |
Valley CC, Lidke KA, Lidke DS. The spatiotemporal organization of ErbB receptors: insights from microscopy. Cold Spring Harbor Perspectives in Biology. 6. PMID 24370847 DOI: 10.1101/Cshperspect.A020735 |
0.485 |
|
2014 |
Valley CC, Low-Nam ST, Steinkamp MP, Wilson BS, Lidke KA, Lidke DS. Single Molecule Imaging Reveals that Activating Kinase Domain Mutations Reduce EGFR Mobility and Enhance Dimerization Biophysical Journal. 106: 102a. DOI: 10.1016/J.Bpj.2013.11.633 |
0.468 |
|
2014 |
Lewis AK, Valley CC, Braun AR, Sachs JN. Quantitative Analysis of Ligand-Induced Supramolecular Clustering of Death Receptor 5 in Jurkat Cells Biophysical Journal. 106: 715a. DOI: 10.1016/J.Bpj.2013.11.3953 |
0.805 |
|
2012 |
Valley CC, Cembran A, Perlmutter JD, Lewis AK, Labello NP, Gao J, Sachs JN. The methionine-aromatic motif plays a unique role in stabilizing protein structure. The Journal of Biological Chemistry. 287: 34979-91. PMID 22859300 DOI: 10.1074/Jbc.M112.374504 |
0.747 |
|
2012 |
Lewis AK, Valley CC, Sachs JN. TNFR1 signaling is associated with backbone conformational changes of receptor dimers consistent with overactivation in the R92Q TRAPS mutant. Biochemistry. 51: 6545-55. PMID 22799488 DOI: 10.1021/Bi3006626 |
0.788 |
|
2012 |
Pineda DM, Rittenhouse DW, Valley CC, Cozzitorto JA, Burkhart RA, Leiby B, Winter JM, Weber MC, Londin ER, Rigoutsos I, Yeo CJ, Gorospe M, Witkiewicz AK, Sachs JN, Brody JR. HuR's post-transcriptional regulation of Death Receptor 5 in pancreatic cancer cells. Cancer Biology & Therapy. 13: 946-55. PMID 22785201 DOI: 10.4161/Cbt.20952 |
0.674 |
|
2012 |
Valley CC, Lewis AK, Mudaliar DJ, Perlmutter JD, Braun AR, Karim CB, Thomas DD, Brody JR, Sachs JN. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor 5 networks that are highly organized. The Journal of Biological Chemistry. 287: 21265-78. PMID 22496450 DOI: 10.1074/Jbc.M111.306480 |
0.755 |
|
2012 |
Valley CC, Lewis AK, Mudaliar D, Sachs JN. Signaling in the Tumor Necrosis Factor Superfamily is Driven by Formation of Receptor Networks: Unraveling the Structural and Dynamic Paradigm Biophysical Journal. 102: 430a. DOI: 10.1016/J.Bpj.2011.11.2355 |
0.792 |
|
2011 |
Valley CC, Perlmutter JD, Braun AR, Sachs JN. NaCl interactions with phosphatidylcholine bilayers do not alter membrane structure but induce long-range ordering of ions and water. The Journal of Membrane Biology. 244: 35-42. PMID 22015614 DOI: 10.1007/S00232-011-9395-1 |
0.716 |
|
2011 |
Rittenhouse DW, Valley C, Cozzitorto JA, Richards NG, Talbott VA, Yeo CJ, Sachs JN, Witkiewicz AK, Brody JR. Abstract 4100: HuR regulates death receptor-5 (DR5, TRAIL-R2)-targeted treatment of pancreatic cancer cells Cancer Research. 71: 4100-4100. DOI: 10.1158/1538-7445.Am2011-4100 |
0.634 |
|
2011 |
Valley CC, Braun AR, Sachs JN. Pre-Ligand Assembly of TNF Receptors Through Covalent and Non-Covalent Interactions Biophysical Journal. 100: 419a-420a. DOI: 10.1016/J.Bpj.2010.12.2485 |
0.785 |
|
2009 |
Valley C, Sachs J. Stabilizing Interactions In TNF Ligand-receptor Binding Biophysical Journal. 96: 446a. DOI: 10.1016/J.Bpj.2008.12.2292 |
0.749 |
|
2008 |
Valley CC, Solodin NM, Powers GL, Ellison SJ, Alarid ET. Temporal variation in estrogen receptor-alpha protein turnover in the presence of estrogen. Journal of Molecular Endocrinology. 40: 23-34. PMID 18096994 DOI: 10.1677/Jme-07-0067 |
0.454 |
|
2006 |
Fowler AM, Solodin NM, Valley CC, Alarid ET. Altered target gene regulation controlled by estrogen receptor-alpha concentration. Molecular Endocrinology (Baltimore, Md.). 20: 291-301. PMID 16179380 DOI: 10.1210/Me.2005-0288 |
0.441 |
|
2005 |
Valley CC, Métivier R, Solodin NM, Fowler AM, Mashek MT, Hill L, Alarid ET. Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor alpha N terminus. Molecular and Cellular Biology. 25: 5417-28. PMID 15964799 DOI: 10.1128/Mcb.25.13.5417-5428.2005 |
0.407 |
|
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