Nadeen O. Chahine, Ph.D. - Publications

Affiliations: 
2006 Columbia University, New York, NY 
Area:
Biomedical Engineering

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kenawy HM, Nuñez MI, Morales X, Lisiewski LE, Burt KG, Kim MKM, Campos L, Kiridly N, Hung CT, Chahine NO. Sex differences in the biomechanical and biochemical responses of caudal rat intervertebral discs to injury. Jor Spine. 6: e1299. PMID 38156061 DOI: 10.1002/jsp2.1299  0.425
2023 Basatvat S, Bach FC, Barcellona MN, Binch AL, Buckley CT, Bueno B, Chahine NO, Chee A, Creemers LB, Dudli S, Fearing B, Ferguson SJ, Gansau J, Gantenbein B, Gawri R, et al. Harmonization and standardization of nucleus pulposus cell extraction and culture methods. Jor Spine. 6: e1238. PMID 36994456 DOI: 10.1002/jsp2.1238  0.639
2023 Kenawy HM, Marshall SL, Rogot J, Lee AJ, Hung CT, Chahine NO. Blocking toll-like receptor 4 mitigates static loading induced pro-inflammatory expression in intervertebral disc motion segments. Journal of Biomechanics. 150: 111491. PMID 36870259 DOI: 10.1016/j.jbiomech.2023.111491  0.513
2023 Pellicore MJ, Gangi LR, Murphy LA, Lee AJ, Jacobsen T, Kenawy HM, Shah RP, Chahine NO, Ateshian GA, Hung CT. Toward defining the role of the synovium in mitigating normal articular cartilage wear and tear. Journal of Biomechanics. 148: 111472. PMID 36753853 DOI: 10.1016/j.jbiomech.2023.111472  0.743
2021 Marshall SL, Jacobsen TD, Emsbo E, Murali A, Anton K, Liu JZ, Lu HH, Chahine NO. Three-Dimensional-Printed Flexible Scaffolds Have Tunable Biomimetic Mechanical Properties for Intervertebral Disc Tissue Engineering. Acs Biomaterials Science & Engineering. PMID 34843224 DOI: 10.1021/acsbiomaterials.1c01326  0.619
2021 Forrester LA, Fang F, Jacobsen T, Hu Y, Kurtaliaj I, Roye BD, Edward Guo X, Chahine NO, Thomopoulos S. Transient Neonatal Shoulder Paralysis Causes Early Osteoarthritis in a Mouse Model. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 34812543 DOI: 10.1002/jor.25225  0.553
2020 Hernandez PA, Jacobsen TD, Barati Z, Chahine NO. Confocal scanning of intervertebral disc cells in 3D: Inside alginate beads and in native microenvironment. Jor Spine. 3: e1106. PMID 33392446 DOI: 10.1002/jsp2.1106  0.742
2020 Hernandez PA, Jacobsen TD, Chahine NO. Actomyosin contractility confers mechanoprotection against TNFα-induced disruption of the intervertebral disc. Science Advances. 6. PMID 32937340 DOI: 10.1126/sciadv.aba2368  0.678
2020 Hernandez PA, Jacobsen TD, Chahine NO. Actomyosin contractility confers mechanoprotection against TNFα-induced disruption of the intervertebral disc. Science Advances. 6: eaba2368. PMID 32875103 DOI: 10.1126/Sciadv.Aba2368  0.767
2020 Wagner EK, Vedadghavami A, Jacobsen TD, Goel SA, Chahine NO, Bajpayee AG. Avidin grafted dextran nanostructure enables a month-long intra-discal retention. Scientific Reports. 10: 12017. PMID 32694557 DOI: 10.1038/S41598-020-68351-1  0.612
2020 Chahine N, Leung E, Cerpa M, Vulapalli M, Boddapati V, Jacobsen T, Lehman RA. 88. Cell stiffness decreases with severity of disc degeneration and inflammatory stimulation The Spine Journal. 20. DOI: 10.1016/J.Spinee.2020.05.191  0.659
2018 Fearing BV, Hernandez PA, Setton LA, Chahine NO. Mechanotransduction and cell biomechanics of the intervertebral disc. Jor Spine. 1. PMID 30569032 DOI: 10.1002/jsp2.1026  0.693
2018 Coury JR, Nixon R, Collins M, Schwartz J, Chahine NO, Grande DA. Oral Administration of a Chemically Modified Curcumin, TRB-N0224, Reduced Inflammatory Cytokines and Cartilage Erosion in a Rabbit ACL Transection Injury Model. Cartilage. 1947603518815263. PMID 30486657 DOI: 10.1177/1947603518815263  0.302
2018 Shah BS, Burt KG, Jacobsen T, Fernandes TD, Alipui DO, Weber KT, Levine M, Chavan SS, Yang H, Tracey KJ, Chahine NO. High mobility group box-1 induces pro-inflammatory signaling in human Nucleus Pulposus cells via Toll-like receptor 4-dependent pathway. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 30273982 DOI: 10.1002/Jor.24154  0.765
2018 Stefani RM, Halder SS, Estell EG, Lee AJ, Silverstein AM, Sobczak E, Chahine NO, Ateshian GA, Shah RP, Hung CT. A Functional Tissue Engineered Synovium Model to Study Osteoarthritis Progression and Treatment. Tissue Engineering. Part A. PMID 30203722 DOI: 10.1089/Ten.Tea.2018.0142  0.661
2017 Khan AN, Jacobsen HE, Khan J, Filippi CG, Levine M, Lehman RA, Riew KD, Lenke LG, Chahine NO. Inflammatory biomarkers of low back pain and disc degeneration: a review. Annals of the New York Academy of Sciences. 1410: 68-84. PMID 29265416 DOI: 10.1111/Nyas.13551  0.592
2017 Shah B, Chahine N. Optimization of Hydrostatic Pressure Loading on Nucleus Pulposus Cells using a High-throughput Bioreactor. Journal of Biomechanical Engineering. PMID 29247254 DOI: 10.1115/1.4038758  0.787
2017 Nguyen QT, Jacobsen TD, Chahine NO. Effects of Inflammation on Multiscale Biomechanical Properties of Cartilaginous Cells and Tissues. Acs Biomaterials Science & Engineering. 3: 2644-2656. PMID 29152560 DOI: 10.1021/Acsbiomaterials.6B00671  0.663
2017 Nguyen QT, Norelli JB, Graver A, Ekstein C, Schwartz J, Chowdhury F, Drakos MC, Grande DA, Chahine NO. Therapeutic Effects of Doxycycline on the Quality of Repaired and Unrepaired Achilles Tendons. The American Journal of Sports Medicine. 363546517716637. PMID 28759732 DOI: 10.1177/0363546517716637  0.585
2016 Maidhof R, Rafiuddin A, Chowdhury F, Jacobsen T, Chahine NO. Timing of mesenchymal stem cell delivery impacts the fate and therapeutic potential in intervertebral disc repair. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 27334230 DOI: 10.1002/Jor.23350  0.767
2016 Jacobsen T, Chahine N. Anti-Inflammatory Agents Prevent Intervertebral Disc Cell Mechanobiological Alterations Global Spine Journal. 6: s-0036-1582599-s-003. DOI: 10.1055/S-0036-1582599  0.591
2015 Weber KT, Jacobsen TD, Maidhof R, Virojanapa J, Overby C, Bloom O, Quraishi S, Levine M, Chahine NO. Developments in intervertebral disc disease research: pathophysiology, mechanobiology, and therapeutics. Current Reviews in Musculoskeletal Medicine. 8: 18-31. PMID 25694233 DOI: 10.1007/S12178-014-9253-8  0.765
2014 Maidhof R, Jacobsen T, Papatheodorou A, Chahine NO. Inflammation induces irreversible biophysical changes in isolated nucleus pulposus cells. Plos One. 9: e99621. PMID 24936787 DOI: 10.1371/Journal.Pone.0099621  0.784
2014 Chahine NO, Collette NM, Thomas CB, Genetos DC, Loots GG. Nanocomposite scaffold for chondrocyte growth and cartilage tissue engineering: effects of carbon nanotube surface functionalization. Tissue Engineering. Part A. 20: 2305-15. PMID 24593020 DOI: 10.1089/Ten.Tea.2013.0328  0.382
2014 Kessler MW, Barr J, Greenwald R, Lane LB, Dines JS, Dines DM, Drakos MC, Grande DA, Chahine NO. Enhancement of Achilles tendon repair mediated by matrix metalloproteinase inhibition via systemic administration of doxycycline. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 32: 500-6. PMID 24346815 DOI: 10.1002/Jor.22564  0.34
2013 Grande DA, Schwartz JA, Brandel E, Chahine NO, Sgaglione N. Articular Cartilage Repair: Where We Have Been, Where We Are Now, and Where We Are Headed. Cartilage. 4: 281-5. PMID 26069673 DOI: 10.1177/1947603513494402  0.328
2013 Chahine NO, Blanchette C, Thomas CB, Lu J, Haudenschild D, Loots GG. Effect of age and cytoskeletal elements on the indentation-dependent mechanical properties of chondrocytes. Plos One. 8: e61651. PMID 23613892 DOI: 10.1371/Journal.Pone.0061651  0.363
2013 Shah V, Bendele A, Dines JS, Kestler HK, Hollinger JO, Chahine NO, Hee CK. Dose-response effect of an intra-tendon application of recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in a rat Achilles tendinopathy model. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 31: 413-20. PMID 22933269 DOI: 10.1002/Jor.22222  0.341
2013 Rajan NE, Bloom O, Maidhof R, Stetson N, Sherry B, Levine M, Chahine NO. Toll-Like Receptor 4 (TLR4) expression and stimulation in a model of intervertebral disc inflammation and degeneration. Spine. 38: 1343-51. PMID 22850250 DOI: 10.1097/Brs.0B013E31826B71F4  0.681
2012 Maidhof R, Alipui DO, Rafiuddin A, Levine M, Grande DA, Chahine NO. Emerging trends in biological therapy for intervertebral disc degeneration. Discovery Medicine. 14: 401-11. PMID 23272692  0.71
2012 O'Connell GD, Lima EG, Bian L, Chahine NO, Albro MB, Cook JL, Ateshian GA, Hung CT. Toward engineering a biological joint replacement. The Journal of Knee Surgery. 25: 187-96. PMID 23057137 DOI: 10.1055/S-0032-1319783  0.758
2012 Ghorayeb SR, Shah NV, Edobor-Osula F, Lane LB, Razzano P, Chahine N, Grande DA. Ultrasonic assessment of extracellular matrix content in healing Achilles tendon. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. 59: 694-702. PMID 22547280 DOI: 10.1109/Tuffc.2012.2247  0.326
2012 Rajan N, Stetson N, Maidhof R, Levine M, Chahine N. In vivo administration of an inflammatory stimulant can trigger loss of biomechanical and biochemical properties of the intervertebral disc Asme 2012 Summer Bioengineering Conference, Sbc 2012. 277-278. DOI: 10.1115/SBC2012-80495  0.667
2012 Maidhof R, Rajan N, Chahine NO. Effect of inflammation on the osmotic response of nucleus pulposus cells Asme 2012 Summer Bioengineering Conference, Sbc 2012. 399-400. DOI: 10.1115/SBC2012-80358  0.677
2009 Daher RJ, Chahine NO, Greenberg AS, Sgaglione NA, Grande DA. New methods to diagnose and treat cartilage degeneration. Nature Reviews. Rheumatology. 5: 599-607. PMID 19786989 DOI: 10.1038/Nrrheum.2009.204  0.364
2009 Chahine NO, Albro MB, Lima EG, Wei VI, Dubois CR, Hung CT, Ateshian GA. Effect of dynamic loading on the transport of solutes into agarose hydrogels. Biophysical Journal. 97: 968-75. PMID 19686643 DOI: 10.1016/J.Bpj.2009.05.047  0.789
2009 Ateshian GA, Rajan V, Chahine NO, Canal CE, Hung CT. Modeling the matrix of articular cartilage using a continuous fiber angular distribution predicts many observed phenomena. Journal of Biomechanical Engineering. 131: 061003. PMID 19449957 DOI: 10.1115/1.3118773  0.657
2009 Ateshian GA, Rajan V, Chahine NO, Guterl CC, Hung CT. Modeling the matrix of articular cartilage using a continuous fiber angular distribution predicts many observed phenomena Proceedings of the Asme Summer Bioengineering Conference 2009, Sbc2009. 283-284. DOI: 10.1115/SBC2009-206408  0.742
2008 Albro MB, Chahine NO, Li R, Yeager K, Hung CT, Ateshian GA. Dynamic loading of deformable porous media can induce active solute transport. Journal of Biomechanics. 41: 3152-7. PMID 18922531 DOI: 10.1016/J.Jbiomech.2008.08.023  0.781
2008 Moffat KL, Sun WH, Pena PE, Chahine NO, Doty SB, Ateshian GA, Hung CT, Lu HH. Characterization of the structure-function relationship at the ligament-to-bone interface. Proceedings of the National Academy of Sciences of the United States of America. 105: 7947-52. PMID 18541916 DOI: 10.1073/Pnas.0712150105  0.632
2007 Albro MB, Chahine NO, Caligaris M, Wei VI, Likhitpanichkul M, Ng KW, Hung CT, Ateshian GA. Osmotic loading of spherical gels: a biomimetic study of hindered transport in the cell protoplasm. Journal of Biomechanical Engineering. 129: 503-10. PMID 17655471 DOI: 10.1115/1.2746371  0.777
2007 Chahine NO, Hung CT, Ateshian GA. In-situ measurements of chondrocyte deformation under transient loading. European Cells & Materials. 13: 100-11; discussion 1. PMID 17538899 DOI: 10.22203/Ecm.V013A11  0.674
2007 Basalo IM, Chahine NO, Kaplun M, Chen FH, Hung CT, Ateshian GA. Chondroitin sulfate reduces the friction coefficient of articular cartilage. Journal of Biomechanics. 40: 1847-54. PMID 17084404 DOI: 10.1016/J.Jbiomech.2006.07.007  0.616
2007 Chahine NO, Ateshian GA, Hung CT. The effect of finite compressive strain on chondrocyte viability in statically loaded bovine articular cartilage. Biomechanics and Modeling in Mechanobiology. 6: 103-11. PMID 16821016 DOI: 10.1007/S10237-006-0041-2  0.661
2006 Moffat KL, Sun WH, Chahine NO, Pena PE, Doty SB, Hung CT, Ateshian GA, Lu HH. Characterization of the mechanical properties and mineral distribution of the anterior cruciate ligament-to-bone insertion site. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 2366-9. PMID 17946954 DOI: 10.1109/IEMBS.2006.259299  0.588
2006 Ateshian G, Chahine N, Wei V, Albro M, Hung C. Computational methods for solute transport in soft tissues and tissue constructs under static and dynamic loading Journal of Biomechanics. 39: S407. DOI: 10.1016/S0021-9290(06)84650-6  0.749
2006 Chahine NO, Hung CT, Ateshian GA. Experimental and finite element analysis of strain fields in chondrocytes and the extracellular matrix of cartilage under physiological loading European Cells and Materials. 12: 18.  0.606
2005 Chahine NO, Chen FH, Hung CT, Ateshian GA. Direct measurement of osmotic pressure of glycosaminoglycan solutions by membrane osmometry at room temperature. Biophysical Journal. 89: 1543-50. PMID 15980166 DOI: 10.1529/Biophysj.104.057315  0.63
2005 Ng KW, Wang CC, Mauck RL, Kelly TA, Chahine NO, Costa KD, Ateshian GA, Hung CT. A layered agarose approach to fabricate depth-dependent inhomogeneity in chondrocyte-seeded constructs. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 23: 134-41. PMID 15607885 DOI: 10.1016/J.Orthres.2004.05.015  0.741
2005 Chahine NO, Lima EG, Wei VI, Hung CT, Ateshian GA. Effect of simultaneous application of direct perfusion and dynamic loading on the transport of dextran into agarose hydrogels Proceedings of the 2005 Summer Bioengineering Conference. 2005: 793-794.  0.68
2005 Canal CE, Chahine NO, Chorney ET, Ateshian GA. Optical measurement of in situ strain fields within bovine humeral head articular layer Proceedings of the 2005 Summer Bioengineering Conference. 2005: 627-628.  0.388
2005 Chahine NO, Chen FH, Hung CT, Ateshian GA. The contribution of osmotic pressure to the effective compressive aggregate modulus of bovine articular cartilage Proceedings of the 2005 Summer Bioengineering Conference. 2005: 759-760.  0.587
2005 Moffat KL, Chahine NO, Hung CT, Ateshian GA, Lu HH. Characterization of the mechanical properties of the ACL-bone insertion site Proceedings of the 2005 Summer Bioengineering Conference. 2005: 1546-1547.  0.412
2004 Chahine NO, Wang CC, Hung CT, Ateshian GA. Anisotropic strain-dependent material properties of bovine articular cartilage in the transitional range from tension to compression. Journal of Biomechanics. 37: 1251-61. PMID 15212931 DOI: 10.1016/J.Jbiomech.2003.12.008  0.708
2004 Ateshian GA, Chahine NO, Basalo IM, Hung CT. The correspondence between equilibrium biphasic and triphasic material properties in mixture models of articular cartilage. Journal of Biomechanics. 37: 391-400. PMID 14757459 DOI: 10.1016/S0021-9290(03)00252-5  0.652
2004 Chahine NO, Hung CT, Lima EG, Ateshian GA. Effect of dynamic deformational loading on the transport of dextran molecules into agarose gels Advances in Bioengineering, Bed. 401-402.  0.684
2003 Wang CC, Chahine NO, Hung CT, Ateshian GA. Optical determination of anisotropic material properties of bovine articular cartilage in compression. Journal of Biomechanics. 36: 339-53. PMID 12594982 DOI: 10.1016/S0021-9290(02)00417-7  0.728
2002 Chahine NO, Wang CCB, Hung CT, Ateshian GA. Determination of poisson's ratios of bovine articular cartilage in tension and compression using osmotic and mechanical loading Asme International Mechanical Engineering Congress and Exposition, Proceedings. 203-204.  0.518
2001 Kelly TAN, Wang CCB, Chahine NO, Ateshian GA, Hung CT. Temporal development of material properties in free swelling chondrocyte-seeded agarose constructs American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 51: 289-290.  0.435
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