Hideyuki Okano - Publications

Affiliations: 
Keio University School of Medicine, Shinjuku-ku, Tōkyō-to, Japan 

375 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Chen Y, Sakurai K, Maeda S, Masui T, Okano H, Dewender J, Seltmann S, Kurtz A, Masuya H, Nakamura Y, Sheldon M, Schneider J, Stacey GN, Panina Y, Fujibuchi W. Integrated Collection of Stem Cell Bank Data, a Data Portal for Standardized Stem Cell Information. Stem Cell Reports. PMID 33740463 DOI: 10.1016/j.stemcr.2021.02.014  0.445
2020 Saito K, Michon F, Yamada A, Inuzuka H, Yamaguchi S, Fukumoto E, Yoshizaki K, Nakamura T, Arakaki M, Chiba Y, Ishikawa M, Okano H, Thesleff I, Fukumoto S. Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ. Iscience. 23: 101329. PMID 32674056 DOI: 10.1016/J.Isci.2020.101329  0.344
2020 Teratani T, Mikami Y, Nakamoto N, Suzuki T, Harada Y, Okabayashi K, Hagihara Y, Taniki N, Kohno K, Sibata S, Miyamoto K, Ishigame H, Chu PS, Sujino T, Suda W, ... ... Okano H, et al. The liver-brain-gut neural arc maintains the T cell niche in the gut. Nature. PMID 32526765 DOI: 10.1038/S41586-020-2425-3  0.337
2020 Popovitchenko T, Park Y, Page NF, Luo X, Krsnik Z, Liu Y, Salamon I, Stephenson JD, Kraushar ML, Volk NL, Patel SM, Wijeratne HRS, Li D, Suthar KS, Wach A, ... ... Okano H, et al. Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development. Nature Communications. 11: 1674. PMID 32245946 DOI: 10.1038/S41467-020-15412-8  0.329
2020 Adams A, Albin S, Amunts K, Asakawa T, Bernard A, Bjaalie JG, Chakli K, Deshler JO, Koninck YD, Ebell CJ, Egan G, Hale ME, Häusser M, Jeong SJ, Illes J, ... ... Okano H, et al. Erratum: International Brain Initiative: An Innovative Framework for Coordinated Global Brain Research Efforts (Neuron (2020) 105(2) (212–216), (S0896627320300027), (10.1016/j.neuron.2020.01.002)) Neuron. 105. PMID 32135092 DOI: 10.1016/J.Neuron.2020.02.022  0.322
2020 Ishikawa M, Aoyama T, Shibata S, Sone T, Miyoshi H, Watanabe H, Nakamura M, Morota S, Uchino H, Yoo AS, Okano H. miRNA-Based Rapid Differentiation of Purified Neurons from hPSCs Advancestowards Quick Screening for Neuronal Disease Phenotypes In Vitro. Cells. 9. PMID 32106535 DOI: 10.3390/Cells9030532  0.358
2020 Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, Furuse T, Shibuya H, Yasuda Y, Yamamori H, Fujimoto M, Nagayasu K, Yamamoto K, Kitagawa K, Miura H, ... ... Okano H, et al. Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes. Nature Communications. 11: 859. PMID 32103003 DOI: 10.1038/S41467-020-14697-Z  0.306
2020 Tamura R, Miyoshi H, Morimoto Y, Oishi Y, Sampetrean O, Iwasawa C, Mine Y, Saya H, Yoshida K, Okano H, Toda M. Gene Therapy Using Neural Stem/Progenitor Cells Derived from Human Induced Pluripotent Stem Cells: Visualization of Migration and Bystander Killing Effect. Human Gene Therapy. PMID 32075424 DOI: 10.1089/Hum.2019.326  0.374
2020 Onodera K, Shimojo D, Ishihara Y, Yano M, Miya F, Banno H, Kuzumaki N, Ito T, Okada R, de Araújo Herculano B, Ohyama M, Yoshida M, Tsunoda T, Katsuno M, Doyu M, ... ... Okano H, et al. Unveiling synapse pathology in spinal bulbar muscular atrophy by genome-wide transcriptome analysis of purified motor neurons derived from disease specific iPSCs. Molecular Brain. 13: 18. PMID 32070397 DOI: 10.1186/S13041-020-0561-1  0.325
2020 Tanimoto Y, Yamasaki T, Nagoshi N, Nishiyama Y, Nori S, Nishimura S, Iida T, Ozaki M, Tsuji O, Ji B, Aoki I, Jinzaki M, Matsumoto M, Fujibayashi Y, Zhang MR, ... ... Okano H, et al. In vivo monitoring of remnant undifferentiated neural cells following human iPS cell-derived neural stem/progenitor cells transplantation. Stem Cells Translational Medicine. PMID 31904914 DOI: 10.1002/Sctm.19-0150  0.371
2019 Tamura R, Miyoshi H, Yoshida K, Okano H, Toda M. Recent progress in the research of suicide gene therapy for malignant glioma. Neurosurgical Review. PMID 31781985 DOI: 10.1007/S10143-019-01203-3  0.315
2019 Kinoshita M, Fujimoto C, Iwasaki S, Kashio A, Kikkawa YS, Kondo K, Okano H, Yamasoba T. Alteration of Musashi1 Intra-cellular Distribution During Regeneration Following Gentamicin-Induced Hair Cell Loss in the Guinea Pig Crista Ampullaris. Frontiers in Cellular Neuroscience. 13: 481. PMID 31708751 DOI: 10.3389/Fncel.2019.00481  0.334
2019 Arai Y, Cwetsch AW, Coppola E, Cipriani S, Nishihara H, Kanki H, Saillour Y, Freret-Hodara B, Dutriaux A, Okada N, Okano H, Dehay C, Nardelli J, Gressens P, Shimogori T, et al. Evolutionary Gain of Dbx1 Expression Drives Subplate Identity in the Cerebral Cortex. Cell Reports. 29: 645-658.e5. PMID 31618633 DOI: 10.1016/J.Celrep.2019.09.007  0.367
2019 Nakamura M, Shiozawa S, Tsuboi D, Amano M, Watanabe H, Maeda S, Kimura T, Yoshimatsu S, Kisa F, Karch CM, Miyasaka T, Takashima A, Sahara N, Hisanaga SI, Ikeuchi T, ... ... Okano H, et al. Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs. Stem Cell Reports. PMID 31543469 DOI: 10.1016/J.Stemcr.2019.08.011  0.304
2019 Cheng YF, Chan YH, Hu CJ, Lu YC, Saeki T, Hosoya M, Saegusa C, Fujioka M, Okano H, Weng SM, Hsu CJ, Chang KH, Wu CC. Generation of a human iPS cell line (CGMH.SLC26A4919-2) from a Pendred syndrome patient carrying SLC26A4 c.919-2A>G splice-site mutation. Stem Cell Research. 40: 101524. PMID 31415960 DOI: 10.1016/J.Scr.2019.101524  0.315
2019 Kuzumaki N, Suda Y, Iwasawa C, Narita M, Sone T, Watanabe M, Maekawa A, Matsumoto T, Akamatsu W, Igarashi K, Tamura H, Takeshima H, Tawfik VL, Ushijima T, Hattori N, ... Okano H, et al. Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease. Brain : a Journal of Neurology. 142: 1675-1689. PMID 31135049 DOI: 10.1093/Brain/Awz084  0.348
2019 Tamura R, Miyoshi H, Sampetrean O, Shinozaki M, Morimoto Y, Iwasawa C, Fukaya R, Mine Y, Masuda H, Maruyama T, Narita M, Saya H, Yoshida K, Okano H, Toda M. Visualization of spatiotemporal dynamics of human glioma stem cell invasion. Molecular Brain. 12: 45. PMID 31060588 DOI: 10.1186/S13041-019-0462-3  0.31
2019 Iwasawa C, Tamura R, Sugiura Y, Suzuki S, Kuzumaki N, Narita M, Suematsu M, Nakamura M, Yoshida K, Toda M, Okano H, Miyoshi H. Increased Cytotoxicity of Herpes Simplex Virus Thymidine Kinase Expression in Human Induced Pluripotent Stem Cells. International Journal of Molecular Sciences. 20. PMID 30769780 DOI: 10.3390/Ijms20040810  0.34
2019 Yoshimatsu S, Okahara J, Sone T, Takeda Y, Nakamura M, Sasaki E, Kishi N, Shiozawa S, Okano H. Robust and efficient knock-in in embryonic stem cells and early-stage embryos of the common marmoset using the CRISPR-Cas9 system. Scientific Reports. 9: 1528. PMID 30728412 DOI: 10.1038/S41598-018-37990-W  0.324
2019 Nishihara K, Shiga T, Nakamura E, Akiyama T, Sasaki T, Suzuki S, Ko MSH, Tada N, Okano H, Akamatsu W. Induced Pluripotent Stem Cells Reprogrammed with Three Inhibitors Show Accelerated Differentiation Potentials with High Levels of 2-Cell Stage Marker Expression. Stem Cell Reports. PMID 30713040 DOI: 10.1016/J.Stemcr.2018.12.018  0.367
2018 Kojima K, Miyoshi H, Nagoshi N, Kohyama J, Itakura G, Kawabata S, Ozaki M, Iida T, Sugai K, Ito S, Fukuzawa R, Yasutake K, Renault-Mihara F, Shibata S, Matsumoto M, ... ... Okano H, et al. Selective Ablation of Tumorigenic Cells Following Human Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cell Transplantation in Spinal Cord Injury. Stem Cells Translational Medicine. PMID 30485733 DOI: 10.1002/Sctm.18-0096  0.351
2018 Tsuji O, Sugai K, Yamaguchi R, Tashiro S, Nagoshi N, Kohyama J, Iida T, Ohkubo T, Itakura G, Isoda M, Shinozaki M, Fujiyoshi K, Kanemura Y, Yamanaka S, Nakamura M, ... Okano H, et al. Laying the groundwork for a first-in-human study of an iPSC-based intervention for spinal cord injury. Stem Cells (Dayton, Ohio). PMID 30371964 DOI: 10.1002/Stem.2926  0.314
2018 Takata N, Sugiura Y, Yoshida K, Koizumi M, Hiroshi N, Honda K, Yano R, Komaki Y, Matsui K, Suematsu M, Mimura M, Okano H, Tanaka KF. Optogenetic astrocyte activation evokes BOLD fMRI response with oxygen consumption without neuronal activity modulation. Glia. PMID 29845643 DOI: 10.1002/Glia.23454  0.319
2018 Iwano S, Sugiyama M, Hama H, Watakabe A, Hasegawa N, Kuchimaru T, Tanaka KZ, Takahashi M, Ishida Y, Hata J, Shimozono S, Namiki K, Fukano T, Kiyama M, Okano H, et al. Single-cell bioluminescence imaging of deep tissue in freely moving animals. Science (New York, N.Y.). 359: 935-939. PMID 29472486 DOI: 10.1126/Science.Aaq1067  0.327
2018 Suda Y, Kuzumaki N, Sone T, Narita M, Tanaka K, Hamada Y, Iwasawa C, Shibasaki M, Maekawa A, Matsuo M, Akamatsu W, Hattori N, Okano H, Narita M. Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson's disease-like motor dysfunction. Molecular Brain. 11: 6. PMID 29458391 DOI: 10.1186/S13041-018-0349-8  0.326
2018 Chai M, Sanosaka T, Okuno H, Zhou Z, Koya I, Banno S, Andoh-Noda T, Tabata Y, Shimamura R, Hayashi T, Ebisawa M, Sasagawa Y, Nikaido I, Okano H, Kohyama J. Chromatin remodeler CHD7 regulates the stem cell identity of human neural progenitors. Genes & Development. PMID 29440260 DOI: 10.1101/Gad.301887.117  0.36
2018 Ogawa Y, Kakumoto K, Yoshida T, Kuwako KI, Miyazaki T, Yamaguchi J, Konno A, Hata J, Uchiyama Y, Hirai H, Watanabe M, Darnell RB, Okano H, Okano HJ. Elavl3 is essential for the maintenance of Purkinje neuron axons. Scientific Reports. 8: 2722. PMID 29426875 DOI: 10.1038/S41598-018-21130-5  0.333
2017 Tateno H, Hiemori K, Hirayasu K, Sougawa N, Fukuda M, Warashina M, Amano M, Funakoshi T, Sadamura Y, Miyagawa S, Saito A, Sawa Y, Shofuda T, Sumida M, Kanemura Y, ... ... Okano H, et al. Development of a practical sandwich assay to detect human pluripotent stem cells using cell culture media. Regenerative Therapy. 6: 1-8. PMID 30271833 DOI: 10.1016/J.Reth.2016.12.002  0.351
2017 Bamba Y, Nonaka M, Sasaki N, Shofuda T, Kanematsu D, Suemizu H, Higuchi Y, Pooh RK, Kanemura Y, Okano H, Yamasaki M. Generation of Induced Pluripotent Stem Cells and Neural Stem/Progenitor Cells from Newborns with Spina Bifida Aperta. Asian Spine Journal. 11: 870-879. PMID 29279741 DOI: 10.4184/Asj.2017.11.6.870  0.344
2017 Okuno H, Renault Mihara F, Ohta S, Fukuda K, Kurosawa K, Akamatsu W, Sanosaka T, Kohyama J, Hayashi K, Nakajima K, Takahashi T, Wysocka J, Kosaki K, Okano H. CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations. Elife. 6. PMID 29179815 DOI: 10.7554/Elife.21114  0.31
2017 Shimogori T, Abe A, Go Y, Hashikawa T, Kishi N, Kikuchi SS, Kita Y, Niimi K, Nishibe H, Okuno M, Saga K, Sakurai M, Sato M, Serizawa T, Suzuki S, ... ... Okano H, et al. Digital gene atlas of neonate common marmoset brain. Neuroscience Research. PMID 29111135 DOI: 10.1016/J.Neures.2017.10.009  0.303
2017 Fukuhara S, Masaoka T, Nishimura S, Nakamura M, Matsuzaki J, Tsugawa H, Miyoshi S, Mori H, Kawase S, Shibata S, Okano H, Kanai T, Suzuki H. Enteric Glial Dysfunction Evoked by Apolipoprotein E Deficiency Contributes to Delayed Gastric Emptying. Digestive Diseases and Sciences. PMID 29098550 DOI: 10.1007/S10620-017-4820-7  0.304
2017 Hayakawa-Yano Y, Suyama S, Nogami M, Yugami M, Koya I, Furukawa T, Zhou L, Abe M, Sakimura K, Takebayashi H, Nakanishi A, Okano H, Yano M. An RNA-binding protein, Qki5, regulates embryonic neural stem cells through pre-mRNA processing in cell adhesion signaling. Genes & Development. PMID 29021239 DOI: 10.1101/Gad.300822.117  0.404
2017 Kodo K, Shibata S, Miyagawa-Tomita S, Ong SG, Takahashi H, Kume T, Okano H, Matsuoka R, Yamagishi H. Regulation of Sema3c and the Interaction between Cardiac Neural Crest and Second Heart Field during Outflow Tract Development. Scientific Reports. 7: 6771. PMID 28754980 DOI: 10.1038/S41598-017-06964-9  0.332
2017 Morizawa YM, Hirayama Y, Ohno N, Shibata S, Shigetomi E, Sui Y, Nabekura J, Sato K, Okajima F, Takebayashi H, Okano H, Koizumi S. Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway. Nature Communications. 8: 28. PMID 28642575 DOI: 10.1038/S41467-017-00037-1  0.306
2017 Itakura G, Kawabata S, Ando M, Nishiyama Y, Sugai K, Ozaki M, Iida T, Ookubo T, Kojima K, Kashiwagi R, Yasutake K, Nakauchi H, Miyoshi H, Nagoshi N, Kohyama J, ... ... Okano H, et al. Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives. Stem Cell Reports. PMID 28262544 DOI: 10.1016/J.Stemcr.2017.02.003  0.337
2017 Tsutsui-Kimura I, Takiue H, Yoshida K, Xu M, Yano R, Ohta H, Nishida H, Bouchekioua Y, Okano H, Uchigashima M, Watanabe M, Takata N, Drew MR, Sano H, Mimura M, et al. Dysfunction of ventrolateral striatal dopamine receptor type 2-expressing medium spiny neurons impairs instrumental motivation. Nature Communications. 8: 14304. PMID 28145402 DOI: 10.1038/Ncomms14304  0.302
2017 Takayama Y, Wakabayashi T, Kushige H, Saito Y, Shibuya Y, Shibata S, Akamatsu W, Okano H, Kida YS. Brief Exposure to Small Molecules Allows Induction of Mouse Embryonic Fibroblasts into Neural Crest-Like Precursors. Febs Letters. PMID 28129669 DOI: 10.1002/1873-3468.12572  0.396
2016 Nakazawa T, Kikuchi M, Ishikawa M, Yamamori H, Nagayasu K, Matsumoto T, Fujimoto M, Yasuda Y, Fujiwara M, Okada S, Matsumura K, Kasai A, Hayata-Takano A, Shintani N, Numata S, ... ... Okano H, et al. Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine. Schizophrenia Research. PMID 28277309 DOI: 10.1016/J.Schres.2016.10.012  0.302
2016 Yamazaki K, Fukushima K, Sugawara M, Tabata Y, Imaizumi Y, Ishihara Y, Ito M, Tsukahara K, Kohyama J, Okano H. Functional Comparison of Neuronal Cells Differentiated from Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells under Different Oxygen and Medium Conditions. Journal of Biomolecular Screening. 21: 1054-1064. PMID 28139961 DOI: 10.1177/1087057116661291  0.36
2016 Ohta S, Yaguchi T, Okuno H, Chneiweiss H, Kawakami Y, Okano H. CHD7 promotes proliferation of neural stem cells mediated by MIF. Molecular Brain. 9: 96. PMID 27955690 DOI: 10.1186/S13041-016-0275-6  0.416
2016 Toyoshima M, Akamatsu W, Okada Y, Ohnishi T, Balan S, Hisano Y, Iwayama Y, Toyota T, Matsumoto T, Itasaka N, Sugiyama S, Tanaka M, Yano M, Dean B, Okano H, et al. Analysis of induced pluripotent stem cells carrying 22q11.2 deletion. Translational Psychiatry. 6: e934. PMID 27801899 DOI: 10.1038/Tp.2016.206  0.318
2016 Fujimori K, Tezuka T, Ishiura H, Mitsui J, Doi K, Yoshimura J, Tada H, Matsumoto T, Isoda M, Hashimoto R, Hattori N, Takahashi T, Morishita S, Tsuji S, Akamatsu W, ... Okano H, et al. Modeling neurological diseases with induced pluripotent cells reprogrammed from immortalized lymphoblastoid cell lines. Molecular Brain. 9: 88. PMID 27716287 DOI: 10.1186/S13041-016-0267-6  0.319
2016 Imamura T, Fujita K, Tagawa K, Ikura T, Chen X, Homma H, Tamura T, Mao Y, Taniguchi JB, Motoki K, Nakabayashi M, Ito N, Yamada K, Tomii K, Okano H, et al. Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries. Scientific Reports. 6: 33861. PMID 27653664 DOI: 10.1038/Srep33861  0.302
2016 Sugai K, Fukuzawa R, Shofuda T, Fukusumi H, Kawabata S, Nishiyama Y, Higuchi Y, Kawai K, Isoda M, Kanematsu D, Hashimoto-Tamaoki T, Kohyama J, Iwanami A, Suemizu H, Ikeda E, ... ... Okano H, et al. Pathological classification of human iPSC-derived neural stem/progenitor cells towards safety assessment of transplantation therapy for CNS diseases. Molecular Brain. 9: 85. PMID 27642008 DOI: 10.1186/S13041-016-0265-8  0.348
2016 Bamba Y, Shofuda T, Kato M, Pooh RK, Tateishi Y, Takanashi J, Utsunomiya H, Sumida M, Kanematsu D, Suemizu H, Higuchi Y, Akamatsu W, Gallagher D, Miller FD, Yamasaki M, ... ... Okano H, et al. In vitro characterization of neurite extension using induced pluripotent stem cells derived from lissencephaly patients with TUBA1A missense mutations. Molecular Brain. 9: 70. PMID 27431206 DOI: 10.1186/S13041-016-0246-Y  0.331
2016 Suzuki N, Hosoya M, Oishi N, Okano H, Fujioka M, Ogawa K. Expression pattern of wolframin, the WFS1 (Wolfram syndrome-1 gene) product, in common marmoset (Callithrix jacchus) cochlea. Neuroreport. PMID 27341211 DOI: 10.1097/Wnr.0000000000000624  0.333
2016 Kunitomi A, Yuasa S, Sugiyama F, Saito Y, Seki T, Kusumoto D, Kashimura S, Takei M, Tohyama S, Hashimoto H, Egashira T, Tanimoto Y, Mizuno S, Tanaka S, Okuno H, ... ... Okano H, et al. H1foo Has a Pivotal Role in Qualifying Induced Pluripotent Stem Cells. Stem Cell Reports. PMID 27237376 DOI: 10.1016/J.Stemcr.2016.04.015  0.344
2016 Miyawaki S, Kawamura Y, Oiwa Y, Shimizu A, Hachiya T, Bono H, Koya I, Okada Y, Kimura T, Tsuchiya Y, Suzuki S, Onishi N, Kuzumaki N, Matsuzaki Y, Narita M, ... ... Okano H, et al. Tumour resistance in induced pluripotent stem cells derived from naked mole-rats. Nature Communications. 7: 11471. PMID 27161380 DOI: 10.1038/Ncomms11471  0.328
2016 Isoda M, Kohyama J, Iwanami A, Sanosaka T, Sugai K, Yamaguchi R, Matsumoto T, Nakamura M, Okano H. Robust production of human neural cells by establishing neuroepithelial-like stem cells from peripheral blood mononuclear cell-derived feeder-free iPSCs under xeno-free conditions. Neuroscience Research. PMID 27083781 DOI: 10.1016/J.Neures.2016.04.003  0.375
2016 Ichiyanagi N, Fujimori K, Yano M, Ishihara-Fujisaki C, Sone T, Akiyama T, Okada Y, Akamatsu W, Matsumoto T, Ishikawa M, Nishimoto Y, Ishihara Y, Sakuma T, Yamamoto T, Tsuiji H, ... ... Okano H, et al. Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells. Stem Cell Reports. PMID 26997647 DOI: 10.1016/J.Stemcr.2016.02.011  0.343
2016 Fukaya R, Ohta S, Yaguchi T, Matsuzaki Y, Sugihara E, Okano H, Saya H, Kawakami Y, Kawase T, Yoshida K, Toda M. MIF maintains the tumorigenic capacity of brain tumor-initiating cells by directly inhibiting p53. Cancer Research. PMID 26980763 DOI: 10.1158/0008-5472.Can-15-1011  0.352
2016 Matsumoto T, Fujimori K, Andoh-Noda T, Ando T, Kuzumaki N, Toyoshima M, Tada H, Imaizumi K, Ishikawa M, Yamaguchi R, Isoda M, Zhou Z, Sato S, Kobayashi T, Ohtaka M, ... ... Okano H, et al. Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells for Neurological Disease Modeling. Stem Cell Reports. PMID 26905201 DOI: 10.1016/J.Stemcr.2016.01.010  0.378
2016 Ogawa Y, Morikawa S, Okano H, Mabuchi Y, Suzuki S, Yaguchi T, Sato Y, Mukai S, Yaguchi S, Inaba T, Okamoto S, Kawakami Y, Tsubota K, Matsuzaki Y, Shimmura S. MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model. Elife. 5. PMID 26809474 DOI: 10.7554/Elife.09394  0.31
2016 Nishiyama Y, Iwanami A, Kohyama J, Itakura G, Kawabata S, Sugai K, Nishimura S, Kashiwagi R, Yasutake K, Isoda M, Matsumoto M, Nakamura M, Okano H. Safe and efficient method for cryopreservation of human induced pluripotent stem cell-derived neural stem and progenitor cells by a programmed freezer with a magnetic field. Neuroscience Research. PMID 26804710 DOI: 10.1016/J.Neures.2015.11.011  0.366
2015 Kawabata S, Takano M, Numasawa-Kuroiwa Y, Itakura G, Kobayashi Y, Nishiyama Y, Sugai K, Nishimura S, Iwai H, Isoda M, Shibata S, Kohyama J, Iwanami A, Toyama Y, Matsumoto M, ... ... Okano H, et al. Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury. Stem Cell Reports. PMID 26724902 DOI: 10.1016/J.Stemcr.2015.11.013  0.343
2015 Grants JM, Ying LT, Yoda A, You CC, Okano H, Sawa H, Taubert S. The Mediator Kinase Module Restrains Epidermal Growth Factor Receptor Signaling and Represses Vulval Cell Fate Specification in Caenorhabditis elegans. Genetics. PMID 26715664 DOI: 10.1534/Genetics.115.180265  0.336
2015 Shimojo D, Onodera K, Doi-Torii Y, Ishihara Y, Hattori C, Miwa Y, Tanaka S, Okada R, Ohyama M, Shoji M, Nakanishi A, Doyu M, Okano H, Okada Y. Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells. Molecular Brain. 8: 79. PMID 26626025 DOI: 10.1186/S13041-015-0172-4  0.336
2015 Imaizumi K, Sone T, Ibata K, Fujimori K, Yuzaki M, Akamatsu W, Okano H. Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes. Stem Cell Reports. PMID 26549851 DOI: 10.1016/J.Stemcr.2015.10.005  0.32
2015 Maekawa M, Iwayama Y, Ohnishi T, Toyoshima M, Shimamoto C, Hisano Y, Toyota T, Balan S, Matsuzaki H, Iwata Y, Takagai S, Yamada K, Ota M, Fukuchi S, Okada Y, ... ... Okano H, et al. Investigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism. Scientific Reports. 5: 16239. PMID 26548558 DOI: 10.1038/Srep16239  0.339
2015 Yasui T, Mabuchi Y, Toriumi H, Ebine T, Niibe K, Houlihan DD, Morikawa S, Onizawa K, Kawana H, Akazawa C, Suzuki N, Nakagawa T, Okano H, Matsuzaki Y. Purified Human Dental Pulp Stem Cells Promote Osteogenic Regeneration. Journal of Dental Research. PMID 26494655 DOI: 10.1177/0022034515610748  0.377
2015 Kohro Y, Sakaguchi E, Tashima R, Tozaki-Saitoh H, Okano H, Inoue K, Tsuda M. A new minimally-invasive method for microinjection into the mouse spinal dorsal horn. Scientific Reports. 5: 14306. PMID 26387932 DOI: 10.1038/Srep14306  0.329
2015 Masuda H, Maruyama T, Gargett CE, Miyazaki K, Matsuzaki Y, Okano H, Tanaka M. Endometrial Side Population Cells: Potential Adult Stem/Progenitor Cells in Endometrium. Biology of Reproduction. 93: 84. PMID 26316062 DOI: 10.1095/Biolreprod.115.131490  0.36
2015 Yokota K, Kobayakawa K, Kubota K, Miyawaki A, Okano H, Ohkawa Y, Iwamoto Y, Okada S. Engrafted Neural Stem/Progenitor Cells Promote Functional Recovery through Synapse Reorganization with Spared Host Neurons after Spinal Cord Injury. Stem Cell Reports. 5: 264-77. PMID 26190527 DOI: 10.1016/J.Stemcr.2015.06.004  0.325
2015 Ono M, Kajitani T, Uchida H, Arase T, Oda H, Uchida S, Ota K, Nagashima T, Masuda H, Miyazaki K, Asada H, Hida N, Mabuchi Y, Morikawa S, Ito M, ... ... Okano H, et al. CD34 and CD49f Double-Positive and Lineage Marker-Negative Cells Isolated from Human Myometrium Exhibit Stem Cell-Like Properties Involved in Pregnancy-Induced Uterine Remodeling. Biology of Reproduction. PMID 26108791 DOI: 10.1095/Biolreprod.114.127126  0.318
2015 Ohta E, Nihira T, Uchino A, Imaizumi Y, Okada Y, Akamatsu W, Takahashi K, Hayakawa H, Nagai M, Ohyama M, Ryo M, Ogino M, Murayama S, Takashima A, Nishiyama K, ... ... Okano H, et al. I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway. Human Molecular Genetics. PMID 26056228 DOI: 10.1093/Hmg/Ddv212  0.322
2015 Ishii K, Suzuki N, Mabuchi Y, Ito N, Kikura N, Fukada S, Okano H, Takeda S, Akazawa C. Muscle Satellite Cell Protein Teneurin-4 Regulates Differentiation During Muscle Regeneration. Stem Cells (Dayton, Ohio). 33: 3017-27. PMID 26013034 DOI: 10.1002/Stem.2058  0.314
2015 Andoh-Noda T, Akamatsu W, Miyake K, Matsumoto T, Yamaguchi R, Sanosaka T, Okada Y, Kobayashi T, Ohyama M, Nakashima K, Kurosawa H, Kubota T, Okano H. Differentiation of multipotent neural stem cells derived from Rett syndrome patients is biased toward the astrocytic lineage. Molecular Brain. 8: 31. PMID 26012557 DOI: 10.1186/S13041-015-0121-2  0.413
2015 Izpisua Belmonte JC, Callaway EM, Caddick SJ, Churchland P, Feng G, Homanics GE, Lee KF, Leopold DA, Miller CT, Mitchell JF, Mitalipov S, Moutri AR, Movshon JA, Okano H, Reynolds JH, et al. Brains, genes, and primates. Neuron. 86: 617-31. PMID 25950631 DOI: 10.1016/J.Neuron.2015.03.021  0.337
2015 Takata N, Yoshida K, Komaki Y, Xu M, Sakai Y, Hikishima K, Mimura M, Okano H, Tanaka KF. Optogenetic activation of CA1 pyramidal neurons at the dorsal and ventral hippocampus evokes distinct brain-wide responses revealed by mouse fMRI. Plos One. 10: e0121417. PMID 25793741 DOI: 10.1371/Journal.Pone.0121417  0.303
2015 Kano S, Yuan M, Cardarelli RA, Maegawa G, Higurashi N, Gaval-Cruz M, Wilson AM, Tristan C, Kondo MA, Chen Y, Koga M, Obie C, Ishizuka K, Seshadri S, Srivastava R, ... ... Okano H, et al. Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy. Current Molecular Medicine. 15: 138-45. PMID 25732146 DOI: 10.2174/1566524015666150303110300  0.352
2015 Lin ZY, Hirano T, Shibata S, Seki NM, Kitajima R, Sedohara A, Siomi MC, Sasaki E, Siomi H, Imamura M, Okano H. Gene expression ontogeny of spermatogenesis in the marmoset uncovers primate characteristics during testicular development. Developmental Biology. 400: 43-58. PMID 25624265 DOI: 10.1016/J.Ydbio.2015.01.014  0.381
2015 Shibata S, Komaki Y, Seki F, Inouye MO, Nagai T, Okano H. Connectomics: comprehensive approaches for whole-brain mapping. Microscopy (Oxford, England). 64: 57-67. PMID 25527636 DOI: 10.1093/Jmicro/Dfu103  0.301
2015 Nishikawa R, Hotta R, Shimojima N, Shibata S, Nagoshi N, Nakamura M, Matsuzaki Y, Okano HJ, Kuroda T, Okano H, Morikawa Y. Migration and differentiation of transplanted enteric neural crest-derived cells in murine model of Hirschsprung's disease. Cytotechnology. 67: 661-70. PMID 25230796 DOI: 10.1007/S10616-014-9754-8  0.395
2015 Ogawa Y, Morikawa S, Okano H, Mabuchi Y, Suzuki S, Yaguchi T, Sato Y, Mukai S, Yaguchi S, Inaba T, Okamoto S, Kawakami Y, Tsubota K, Matsuzaki Y, Shimmura S. Author response: MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model Elife. DOI: 10.7554/Elife.09394.034  0.312
2015 Belmonte JCI, Callaway EM, Caddick SJ, Churchland P, Feng G, Homanics GE, Lee KF, Leopold DA, Miller CT, Mitchell JF, Mitalipov S, Moutri AR, Movshon JA, Okano H, Reynolds JH, et al. Corrigendum to Brains, Genes, and Primates [Neuron 86, 617-631; May 6, 2015] Neuron. 87: 671. DOI: 10.1016/J.Neuron.2015.07.021  0.318
2014 Kawase S, Kuwako K, Imai T, Renault-Mihara F, Yaguchi K, Itohara S, Okano H. Regulatory factor X transcription factors control Musashi1 transcription in mouse neural stem/progenitor cells. Stem Cells and Development. 23: 2250-61. PMID 25058468 DOI: 10.1089/Scd.2014.0219  0.384
2014 Yoshida T, Ozawa Y, Suzuki K, Yuki K, Ohyama M, Akamatsu W, Matsuzaki Y, Shimmura S, Mitani K, Tsubota K, Okano H. The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa. Molecular Brain. 7: 45. PMID 24935155 DOI: 10.1186/1756-6606-7-45  0.325
2014 Sakurai M, Kunimoto H, Watanabe N, Fukuchi Y, Yuasa S, Yamazaki S, Nishimura T, Sadahira K, Fukuda K, Okano H, Nakauchi H, Morita Y, Matsumura I, Kudo K, Ito E, et al. Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients. Leukemia. 28: 2344-54. PMID 24732596 DOI: 10.1038/Leu.2014.136  0.332
2014 Zhou Z, Kohda K, Ibata K, Kohyama J, Akamatsu W, Yuzaki M, Okano HJ, Sasaki E, Okano H. Reprogramming non-human primate somatic cells into functional neuronal cells by defined factors. Molecular Brain. 7: 24. PMID 24694048 DOI: 10.1186/1756-6606-7-24  0.381
2014 Itaba N, Wairagu PM, Aramaki N, Yasui T, Matsumi Y, Kono Y, Phan AN, Otsu M, Kunisada T, Nakamura Y, Okano H, Jeong Y, Shiota G. Nuclear receptor gene alteration in human induced pluripotent stem cells with hepatic differentiation propensity. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 44: E408-19. PMID 24636009 DOI: 10.1111/Hepr.12329  0.536
2014 DeBoer EM, Azevedo R, Vega TA, Brodkin J, Akamatsu W, Okano H, Wagner GC, Rasin MR. Prenatal deletion of the RNA-binding protein HuD disrupts postnatal cortical circuit maturation and behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3674-86. PMID 24599466 DOI: 10.1523/Jneurosci.3703-13.2014  0.334
2014 Bae BI, Tietjen I, Atabay KD, Evrony GD, Johnson MB, Asare E, Wang PP, Murayama AY, Im K, Lisgo SN, Overman L, Šestan N, Chang BS, Barkovich AJ, Grant PE, ... ... Okano H, et al. Evolutionarily dynamic alternative splicing of GPR56 regulates regional cerebral cortical patterning. Science (New York, N.Y.). 343: 764-8. PMID 24531968 DOI: 10.1126/Science.1244392  0.345
2014 Yamaguchi S, Marumoto T, Nii T, Kawano H, Liao J, Nagai Y, Okada M, Takahashi A, Inoue H, Sasaki E, Fujii H, Okano S, Ebise H, Sato T, Suyama M, ... Okano H, et al. Characterization of common marmoset dysgerminoma-like tumor induced by the lentiviral expression of reprogramming factors. Cancer Science. 105: 402-8. PMID 24521492 DOI: 10.1111/Cas.12367  0.31
2014 Kim C, Kim W, Lee H, Ji E, Choe YJ, Martindale JL, Akamatsu W, Okano H, Kim HS, Nam SW, Gorospe M, Lee EK. The RNA-binding protein HuD regulates autophagosome formation in pancreatic β cells by promoting autophagy-related gene 5 expression. The Journal of Biological Chemistry. 289: 112-21. PMID 24275661 DOI: 10.1074/Jbc.M113.474700  0.337
2014 Tomioka T, Shimazaki T, Yamauchi T, Oki T, Ohgoh M, Okano H. LIM homeobox 8 (Lhx8) is a key regulator of the cholinergic neuronal function via a tropomyosin receptor kinase A (TrkA)-mediated positive feedback loop. The Journal of Biological Chemistry. 289: 1000-10. PMID 24265310 DOI: 10.1074/Jbc.M113.494385  0.344
2014 Morizane R, Monkawa T, Fujii S, Yamaguchi S, Homma K, Matsuzaki Y, Okano H, Itoh H. Kidney specific protein-positive cells derived from embryonic stem cells reproduce tubular structures in vitro and differentiate into renal tubular cells. Plos One. 8: e64843. PMID 23755150 DOI: 10.1371/Journal.Pone.0064843  0.359
2014 Fukuhara S, Suzuki H, Masaoka T, Matsuzaki J, Tsugawa H, Okada S, Mori H, Nishimura S, Kawase S, Nakamura M, Okano H, Kanai T. 66 Neural Stem Cell Transplantation Restored the Delayed Gastric Emptying in Apolipoprotein E-Knockout Mice Gastroenterology. 146: S-19. DOI: 10.1016/S0016-5085(14)60066-4  0.301
2013 Shofuda T, Kanematsu D, Fukusumi H, Yamamoto A, Bamba Y, Yoshitatsu S, Suemizu H, Nakamura M, Sugimoto Y, Furue MK, Kohara A, Akamatsu W, Okada Y, Okano H, Yamasaki M, et al. Human Decidua-Derived Mesenchymal Cells Are a Promising Source for the Generation and Cell Banking of Human Induced Pluripotent Stem Cells. Cell Medicine. 4: 125-47. PMID 26858858 DOI: 10.3727/215517912X658918  0.373
2013 Horiuchi Y, Kano S, Ishizuka K, Cascella NG, Ishii S, Talbot CC, Jaffe AE, Okano H, Pevsner J, Colantuoni C, Sawa A. Olfactory cells via nasal biopsy reflect the developing brain in gene expression profiles: utility and limitation of the surrogate tissues in research for brain disorders. Neuroscience Research. 77: 247-50. PMID 24120685 DOI: 10.1016/J.Neures.2013.09.010  0.381
2013 Ohta S, Misawa A, Lefebvre V, Okano H, Kawakami Y, Toda M. Sox6 up-regulation by macrophage migration inhibitory factor promotes survival and maintenance of mouse neural stem/progenitor cells. Plos One. 8: e74315. PMID 24066135 DOI: 10.1371/Journal.Pone.0074315  0.397
2013 Sato H, Shibata M, Shimizu T, Shibata S, Toriumi H, Ebine T, Kuroi T, Iwashita T, Funakubo M, Kayama Y, Akazawa C, Wajima K, Nakagawa T, Okano H, Suzuki N. Differential cellular localization of antioxidant enzymes in the trigeminal ganglion. Neuroscience. 248: 345-58. PMID 23774632 DOI: 10.1016/J.Neuroscience.2013.06.010  0.334
2013 Natsume A, Ito M, Katsushima K, Ohka F, Hatanaka A, Shinjo K, Sato S, Takahashi S, Ishikawa Y, Takeuchi I, Shimogawa H, Uesugi M, Okano H, Kim SU, Wakabayashi T, et al. Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma. Cancer Research. 73: 4559-70. PMID 23720055 DOI: 10.1158/0008-5472.Can-13-0109  0.345
2013 Lin CH, Lee HT, Lee SD, Lee W, Cho CW, Lin SZ, Wang HJ, Okano H, Su CY, Yu YL, Hsu CY, Shyu WC. Role of HIF-1α-activated Epac1 on HSC-mediated neuroplasticity in stroke model. Neurobiology of Disease. 58: 76-91. PMID 23702312 DOI: 10.1016/J.Nbd.2013.05.006  0.334
2013 Higurashi N, Uchida T, Lossin C, Misumi Y, Okada Y, Akamatsu W, Imaizumi Y, Zhang B, Nabeshima K, Mori MX, Katsurabayashi S, Shirasaka Y, Okano H, Hirose S. A human Dravet syndrome model from patient induced pluripotent stem cells. Molecular Brain. 6: 19. PMID 23639079 DOI: 10.1186/1756-6606-6-19  0.318
2013 Ohta S, Imaizumi Y, Akamatsu W, Okano H, Kawakami Y. Generation of human melanocytes from induced pluripotent stem cells. Methods in Molecular Biology (Clifton, N.J.). 989: 193-215. PMID 23483397 DOI: 10.1007/978-1-62703-330-5_16  0.356
2013 Kanda H, Nguyen A, Chen L, Okano H, Hariharan IK. The Drosophila ortholog of MLL3 and MLL4, trithorax related, functions as a negative regulator of tissue growth. Molecular and Cellular Biology. 33: 1702-10. PMID 23459941 DOI: 10.1128/Mcb.01585-12  0.338
2013 Okano H, Nakamura M, Yoshida K, Okada Y, Tsuji O, Nori S, Ikeda E, Yamanaka S, Miura K. Steps toward safe cell therapy using induced pluripotent stem cells. Circulation Research. 112: 523-33. PMID 23371901 DOI: 10.1161/Circresaha.111.256149  0.347
2013 Nihei Y, Ito D, Okada Y, Akamatsu W, Yagi T, Yoshizaki T, Okano H, Suzuki N. Enhanced aggregation of androgen receptor in induced pluripotent stem cell-derived neurons from spinal and bulbar muscular atrophy. The Journal of Biological Chemistry. 288: 8043-52. PMID 23364790 DOI: 10.1074/Jbc.M112.408211  0.351
2013 Mizutari K, Fujioka M, Hosoya M, Bramhall N, Okano HJ, Okano H, Edge AS. Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma. Neuron. 77: 58-69. PMID 23312516 DOI: 10.1016/J.Neuron.2012.10.032  0.363
2013 Hirata A, Utikal J, Yamashita S, Aoki H, Watanabe A, Yamamoto T, Okano H, Bardeesy N, Kunisada T, Ushijima T, Hara A, Jaenisch R, Hochedlinger K, Yamada Y. Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium. Development (Cambridge, England). 140: 66-75. PMID 23222438 DOI: 10.1242/Jcs.130047  0.366
2013 Hatou S, Yoshida S, Higa K, Miyashita H, Inagaki E, Okano H, Tsubota K, Shimmura S. Functional corneal endothelium derived from corneal stroma stem cells of neural crest origin by retinoic acid and Wnt/β-catenin signaling. Stem Cells and Development. 22: 828-39. PMID 22974347 DOI: 10.1089/Scd.2012.0286  0.366
2013 Nishimoto Y, Okano HJ, Imai T, Poole AJ, Suzuki N, Keirstead HS, Okano H. Cellular toxicity induced by the 26-kDa fragment and amyotrophic lateral sclerosis-associated mutant forms of TAR DNA-binding protein 43 in human embryonic stem cell-derived motor neurons Neurology and Clinical Neuroscience. 1: 24-31. DOI: 10.1002/Ncn3.2  0.325
2012 Sakai D, Nakamura Y, Nakai T, Mishima T, Kato S, Grad S, Alini M, Risbud MV, Chan D, Cheah KS, Yamamura K, Masuda K, Okano H, Ando K, Mochida J. Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc. Nature Communications. 3: 1264. PMID 23232394 DOI: 10.1038/Ncomms2226  0.32
2012 Shimada H, Okada Y, Ibata K, Ebise H, Ota S, Tomioka I, Nomura T, Maeda T, Kohda K, Yuzaki M, Sasaki E, Nakamura M, Okano H. Efficient derivation of multipotent neural stem/progenitor cells from non-human primate embryonic stem cells. Plos One. 7: e49469. PMID 23166679 DOI: 10.1371/Journal.Pone.0049469  0.377
2012 Kuzumaki N, Suzuki A, Narita M, Hosoya T, Nagasawa A, Imai S, Yamamizu K, Morita H, Suzuki T, Okada Y, Okano HJ, Yamashita JK, Okano H, Narita M. Multiple analyses of G-protein coupled receptor (GPCR) expression in the development of gefitinib-resistance in transforming non-small-cell lung cancer. Plos One. 7: e44368. PMID 23144692 DOI: 10.1371/Journal.Pone.0044368  0.323
2012 Kumamaru H, Ohkawa Y, Saiwai H, Yamada H, Kubota K, Kobayakawa K, Akashi K, Okano H, Iwamoto Y, Okada S. Direct isolation and RNA-seq reveal environment-dependent properties of engrafted neural stem/progenitor cells. Nature Communications. 3: 1140. PMID 23072808 DOI: 10.1038/Ncomms2132  0.34
2012 Imaizumi Y, Okada Y, Akamatsu W, Koike M, Kuzumaki N, Hayakawa H, Nihira T, Kobayashi T, Ohyama M, Sato S, Takanashi M, Funayama M, Hirayama A, Soga T, Hishiki T, ... ... Okano H, et al. Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Molecular Brain. 5: 35. PMID 23039195 DOI: 10.1186/1756-6606-5-35  0.322
2012 Ince-Dunn G, Okano HJ, Jensen KB, Park WY, Zhong R, Ule J, Mele A, Fak JJ, Yang C, Zhang C, Yoo J, Herre M, Okano H, Noebels JL, Darnell RB. Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability. Neuron. 75: 1067-80. PMID 22998874 DOI: 10.1016/J.Neuron.2012.07.009  0.337
2012 Ito D, Okano H, Suzuki N. Accelerating progress in induced pluripotent stem cell research for neurological diseases. Annals of Neurology. 72: 167-74. PMID 22926850 DOI: 10.1002/Ana.23596  0.322
2012 Imamura M, Okuno H, Tomioka I, Kawamura Y, Lin ZY, Nakajima R, Akamatsu W, Okano HJ, Matsuzaki Y, Sasaki E, Okano H. Derivation of induced pluripotent stem cells by retroviral gene transduction in mammalian species. Methods in Molecular Biology (Clifton, N.J.). 925: 21-48. PMID 22907488 DOI: 10.1007/978-1-62703-011-3_2  0.358
2012 Yagi T, Kosakai A, Ito D, Okada Y, Akamatsu W, Nihei Y, Nabetani A, Ishikawa F, Arai Y, Hirose N, Okano H, Suzuki N. Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research. Plos One. 7: e41572. PMID 22848530 DOI: 10.1371/Journal.Pone.0041572  0.331
2012 Mukai A, Yamamoto-Hino M, Komada M, Okano H, Goto S. Balanced ubiquitination determines cellular responsiveness to extracellular stimuli. Cellular and Molecular Life Sciences : Cmls. PMID 22825661 DOI: 10.1007/S00018-012-1084-4  0.325
2012 Suyama S, Sunabori T, Kanki H, Sawamoto K, Gachet C, Koizumi S, Okano H. Purinergic signaling promotes proliferation of adult mouse subventricular zone cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9238-47. PMID 22764232 DOI: 10.1523/Jneurosci.4001-11.2012  0.734
2012 Mochizuki S, Soejima K, Shimoda M, Abe H, Sasaki A, Okano HJ, Okano H, Okada Y. Effect of ADAM28 on carcinoma cell metastasis by cleavage of von Willebrand factor. Journal of the National Cancer Institute. 104: 906-22. PMID 22636800 DOI: 10.1093/Jnci/Djs232  0.307
2012 Hirota Y, Sawada M, Kida YS, Huang SH, Yamada O, Sakaguchi M, Ogura T, Okano H, Sawamoto K. Roles of planar cell polarity signaling in maturation of neuronal precursor cells in the postnatal mouse olfactory bulb. Stem Cells (Dayton, Ohio). 30: 1726-33. PMID 22628050 DOI: 10.1002/Stem.1137  0.777
2012 Seko Y, Azuma N, Kaneda M, Nakatani K, Miyagawa Y, Noshiro Y, Kurokawa R, Okano H, Umezawa A. Derivation of human differential photoreceptor-like cells from the iris by defined combinations of CRX, RX and NEUROD. Plos One. 7: e35611. PMID 22558175 DOI: 10.1371/Journal.Pone.0035611  0.378
2012 Mashiko H, Yoshida AC, Kikuchi SS, Niimi K, Takahashi E, Aruga J, Okano H, Shimogori T. Comparative anatomy of marmoset and mouse cortex from genomic expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5039-53. PMID 22496550 DOI: 10.1523/Jneurosci.4788-11.2012  0.322
2012 Sakaguchi M, Okano H. Neural stem cells, adult neurogenesis, and galectin-1: from bench to bedside. Developmental Neurobiology. 72: 1059-67. PMID 22488739 DOI: 10.1002/Dneu.22023  0.557
2012 Ohta S, Misawa A, Fukaya R, Inoue S, Kanemura Y, Okano H, Kawakami Y, Toda M. Macrophage migration inhibitory factor (MIF) promotes cell survival and proliferation of neural stem/progenitor cells. Journal of Cell Science. 125: 3210-20. PMID 22454509 DOI: 10.1242/Dev.088658  0.383
2012 Shibata S, Umei M, Kawahara H, Yano M, Makino S, Okano H. Characterization of the RNA-binding protein Musashi1 in zebrafish. Brain Research. 1462: 162-73. PMID 22429745 DOI: 10.1016/J.Brainres.2012.01.068  0.389
2012 Muto J, Imai T, Ogawa D, Nishimoto Y, Okada Y, Mabuchi Y, Kawase T, Iwanami A, Mischel PS, Saya H, Yoshida K, Matsuzaki Y, Okano H. RNA-binding protein Musashi1 modulates glioma cell growth through the post-transcriptional regulation of Notch and PI3 kinase/Akt signaling pathways. Plos One. 7: e33431. PMID 22428049 DOI: 10.1371/Journal.Pone.0033431  0.38
2012 Lin ZY, Imamura M, Sano C, Nakajima R, Suzuki T, Yamadera R, Takehara Y, Okano HJ, Sasaki E, Okano H. Molecular signatures to define spermatogenic cells in common marmoset (Callithrix jacchus). Reproduction (Cambridge, England). 143: 597-609. PMID 22323619 DOI: 10.1530/Rep-11-0215  0.379
2012 Kelava I, Reillo I, Murayama AY, Kalinka AT, Stenzel D, Tomancak P, Matsuzaki F, Lebrand C, Sasaki E, Schwamborn JC, Okano H, Huttner WB, Borrell V. Abundant occurrence of basal radial glia in the subventricular zone of embryonic neocortex of a lissencephalic primate, the common marmoset Callithrix jacchus. Cerebral Cortex (New York, N.Y. : 1991). 22: 469-81. PMID 22114084 DOI: 10.1093/Cercor/Bhr301  0.38
2012 Yaguchi S, Shimmura S, Inaba T, Matsuzaki Y, Okamoto S, Kawakami Y, Ogawa Y, Morikawa S, Okano H, Mabuchi Y, Suzuki S, Tsubota K, Yaguchi T. Donor mesenchymal stem cells trigger chronic graft-versus-host disease following minor antigen-mismatched bone marrow transplantation Nature Precedings. 7: 1-1. DOI: 10.1038/Npre.2012.6843.1  0.302
2011 Yoshida S, Yasuda M, Miyashita H, Ogawa Y, Yoshida T, Matsuzaki Y, Tsubota K, Okano H, Shimmura S. Generation of stratified squamous epithelial progenitor cells from mouse induced pluripotent stem cells. Plos One. 6: e28856. PMID 22174914 DOI: 10.1371/Journal.Pone.0028856  0.353
2011 Yamasaki T, Kawasaki H, Arakawa S, Shimizu K, Shimizu S, Reiner O, Okano H, Nishina S, Azuma N, Penninger JM, Katada T, Nishina H. Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16872-83. PMID 22090513 DOI: 10.1523/Jneurosci.1111-11.2011  0.341
2011 Yamane J, Ishibashi S, Sakaguchi M, Kuroiwa T, Kanemura Y, Nakamura M, Miyoshi H, Sawamoto K, Toyama Y, Mizusawa H, Okano H. Transplantation of human neural stem/progenitor cells overexpressing galectin-1 improves functional recovery from focal brain ischemia in the Mongolian gerbil. Molecular Brain. 4: 35. PMID 21951913 DOI: 10.1186/1756-6606-4-35  0.728
2011 Katoh H, Shibata S, Fukuda K, Sato M, Satoh E, Nagoshi N, Minematsu T, Matsuzaki Y, Akazawa C, Toyama Y, Nakamura M, Okano H. The dual origin of the peripheral olfactory system: placode and neural crest. Molecular Brain. 4: 34. PMID 21943152 DOI: 10.1186/1756-6606-4-34  0.363
2011 Yagi T, Ito D, Okada Y, Akamatsu W, Nihei Y, Yoshizaki T, Yamanaka S, Okano H, Suzuki N. Modeling familial Alzheimer's disease with induced pluripotent stem cells. Human Molecular Genetics. 20: 4530-9. PMID 21900357 DOI: 10.1093/Hmg/Ddr394  0.326
2011 Sakaguchi M, Arruda-Carvalho M, Kang NH, Imaizumi Y, Poirier F, Okano H, Frankland PW. Impaired spatial and contextual memory formation in galectin-1 deficient mice. Molecular Brain. 4: 33. PMID 21884595 DOI: 10.1186/1756-6606-4-33  0.659
2011 Nakamura M, Tsuji O, Bregman BS, Toyama Y, Okano H. Mimicking the neurotrophic factor profile of embryonic spinal cord controls the differentiation potential of spinal progenitors into neuronal cells. Plos One. 6: e20717. PMID 21698095 DOI: 10.1371/Journal.Pone.0020717  0.37
2011 Tabuse M, Ohta S, Ohashi Y, Fukaya R, Misawa A, Yoshida K, Kawase T, Saya H, Thirant C, Chneiweiss H, Matsuzaki Y, Okano H, Kawakami Y, Toda M. Functional analysis of HOXD9 in human gliomas and glioma cancer stem cells. Molecular Cancer. 10: 60. PMID 21600039 DOI: 10.1186/1476-4598-10-60  0.397
2011 Fujioka M, Tokano H, Fujioka KS, Okano H, Edge AS. Generating mouse models of degenerative diseases using Cre/lox-mediated in vivo mosaic cell ablation. The Journal of Clinical Investigation. 121: 2462-9. PMID 21576819 DOI: 10.1172/Jci45081  0.343
2011 Kawase S, Imai T, Miyauchi-Hara C, Yaguchi K, Nishimoto Y, Fukami S, Matsuzaki Y, Miyawaki A, Itohara S, Okano H. Identification of a novel intronic enhancer responsible for the transcriptional regulation of musashi1 in neural stem/progenitor cells. Molecular Brain. 4: 14. PMID 21486496 DOI: 10.1186/1756-6606-4-14  0.419
2011 Ishizuka K, Kamiya A, Oh EC, Kanki H, Seshadri S, Robinson JF, Murdoch H, Dunlop AJ, Kubo K, Furukori K, Huang B, Zeledon M, Hayashi-Takagi A, Okano H, Nakajima K, et al. DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature. 473: 92-6. PMID 21471969 DOI: 10.1038/Nature09859  0.37
2011 Cucchiaroni ML, Freestone PS, Berretta N, Viscomi MT, Bisicchia E, Okano H, Molinari M, Bernardi G, Lipski J, Mercuri NB, Guatteo E. Properties of dopaminergic neurons in organotypic mesencephalic-striatal co-cultures--evidence for a facilitatory effect of dopamine on the glutamatergic input mediated by α-1 adrenergic receptors. The European Journal of Neuroscience. 33: 1622-36. PMID 21453288 DOI: 10.1111/J.1460-9568.2011.07659.X  0.307
2011 Kawahara H, Okada Y, Imai T, Iwanami A, Mischel PS, Okano H. Musashi1 cooperates in abnormal cell lineage protein 28 (Lin28)-mediated let-7 family microRNA biogenesis in early neural differentiation. The Journal of Biological Chemistry. 286: 16121-30. PMID 21378162 DOI: 10.1074/Jbc.M110.199166  0.337
2011 Imaizumi Y, Sakaguchi M, Morishita T, Ito M, Poirier F, Sawamoto K, Okano H. Galectin-1 is expressed in early-type neural progenitor cells and down-regulates neurogenesis in the adult hippocampus. Molecular Brain. 4: 7. PMID 21269521 DOI: 10.1016/J.Neures.2010.07.1619  0.775
2011 Ohta S, Imaizumi Y, Okada Y, Akamatsu W, Kuwahara R, Ohyama M, Amagai M, Matsuzaki Y, Yamanaka S, Okano H, Kawakami Y. Generation of human melanocytes from induced pluripotent stem cells. Plos One. 6: e16182. PMID 21249204 DOI: 10.1371/Journal.Pone.0016182  0.373
2011 Sawamoto K, Hirota Y, Alfaro-Cervello C, Soriano-Navarro M, He X, Hayakawa-Yano Y, Yamada M, Hikishima K, Tabata H, Iwanami A, Nakajima K, Toyama Y, Itoh T, Alvarez-Buylla A, Garcia-Verdugo JM, ... Okano H, et al. Cellular composition and organization of the subventricular zone and rostral migratory stream in the adult and neonatal common marmoset brain. The Journal of Comparative Neurology. 519: 690-713. PMID 21246550 DOI: 10.1002/Cne.22543  0.71
2011 Tamura Y, Matsumura K, Sano M, Tabata H, Kimura K, Ieda M, Arai T, Ohno Y, Kanazawa H, Yuasa S, Kaneda R, Makino S, Nakajima K, Okano H, Fukuda K. Neural crest-derived stem cells migrate and differentiate into cardiomyocytes after myocardial infarction. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 582-9. PMID 21212399 DOI: 10.1161/Atvbaha.110.214726  0.353
2011 Igaki T, Kanda H, Okano H, Xu T, Miura M. Eiger and wengen: the Drosophila orthologs of TNF/TNFR. Advances in Experimental Medicine and Biology. 691: 45-50. PMID 21153308 DOI: 10.1007/978-1-4419-6612-4_5  0.341
2011 Ohta S, Misawa A, Okuno H, Fukuda K, Akamatsu W, Kawakami Y, Okano H. Generation of neural crest progenitor cells from human induced pluripotent stem cells by a simple method Neuroscience Research. 71: e127. DOI: 10.1016/J.Neures.2011.07.541  0.356
2011 Hara K, Inoue S, Muto J, Kaneko N, Toyoda F, Hikishima K, Itoh T, Sawamoto K, Yoshida K, Kawase T, Okano H. Development and analysis of less invasive transient middle cerebral artery occlusion model on non-human primate Neuroscience Research. 71: e403-e404. DOI: 10.1016/J.Neures.2011.07.1768  0.628
2011 Nakaguchi K, Kaneko N, Aoyama M, Okada Y, Asai K, Okano H, Sawamoto K. Directional migration of new neurons generated by transplanted human iPS cell-derived neural stem cells in the striatum of a mouse stroke model Neuroscience Research. 71: e338. DOI: 10.1016/J.Neures.2011.07.1483  0.702
2011 Ishii S, Okada Y, Miya F, Tsunoda T, Shimazaki T, Okano H. Efficient generation and developmental analysis of basal forebrain cholinergic neurons from mouse embryonic stem cells Neuroscience Research. 71: e332. DOI: 10.1016/J.Neures.2011.07.1451  0.371
2011 Tsuboi D, Iizuka Y, Taya S, Shiina N, Okano H, Mikoshiba K, Kaibuchi K. Disrupted-in-Schizoprenia-1 regulates transport of neuronal mRNA for neural plasticity Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.1412  0.338
2010 Horisawa K, Imai T, Okano H, Yanagawa H. The Musashi family RNA-binding proteins in stem cells. Biomolecular Concepts. 1: 59-66. PMID 25961986 DOI: 10.1515/Bmc.2010.005  0.391
2010 Shibata S, Yasuda A, Renault-Mihara F, Suyama S, Katoh H, Inoue T, Inoue YU, Nagoshi N, Sato M, Nakamura M, Akazawa C, Okano H. Sox10-Venus mice: a new tool for real-time labeling of neural crest lineage cells and oligodendrocytes. Molecular Brain. 3: 31. PMID 21034515 DOI: 10.1186/1756-6606-3-31  0.384
2010 Ellis J, Baum C, Benvenisty N, Mostoslavsky G, Okano H, Stanford WL, Porteus M, Sadelain M. Benefits of utilizing gene-modified iPSCs for clinical applications. Cell Stem Cell. 7: 429-30. PMID 20887948 DOI: 10.1016/J.Stem.2010.09.010  0.333
2010 Ikeda M, Hirota Y, Sakaguchi M, Yamada O, Kida YS, Ogura T, Otsuka T, Okano H, Sawamoto K. Expression and proliferation-promoting role of Diversin in the neuronally committed precursor cells migrating in the adult mouse brain. Stem Cells (Dayton, Ohio). 28: 2017-26. PMID 20827749 DOI: 10.1002/Stem.516  0.773
2010 Wang XY, Penalva LO, Yuan H, Linnoila RI, Lu J, Okano H, Glazer RI. Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival. Molecular Cancer. 9: 221. PMID 20727204 DOI: 10.1186/1476-4598-9-221  0.306
2010 Aihara Y, Hayashi Y, Hirata M, Ariki N, Shibata S, Nagoshi N, Nakanishi M, Ohnuma K, Warashina M, Michiue T, Uchiyama H, Okano H, Asashima M, Furue MK. Induction of neural crest cells from mouse embryonic stem cells in a serum-free monolayer culture. The International Journal of Developmental Biology. 54: 1287-94. PMID 20711997 DOI: 10.1387/Ijdb.103173Ya  0.384
2010 Kuwako K, Kakumoto K, Imai T, Igarashi M, Hamakubo T, Sakakibara S, Tessier-Lavigne M, Okano HJ, Okano H. Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression. Neuron. 67: 407-21. PMID 20696379 DOI: 10.1016/J.Neuron.2010.07.005  0.344
2010 Hirota Y, Meunier A, Huang S, Shimozawa T, Yamada O, Kida YS, Inoue M, Ito T, Kato H, Sakaguchi M, Sunabori T, Nakaya MA, Nonaka S, Ogura T, Higuchi H, ... Okano H, et al. Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II. Development (Cambridge, England). 137: 3037-46. PMID 20685736 DOI: 10.1242/Dev.050120  0.739
2010 Kaneko N, Marín O, Koike M, Hirota Y, Uchiyama Y, Wu JY, Lu Q, Tessier-Lavigne M, Alvarez-Buylla A, Okano H, Rubenstein JL, Sawamoto K. New neurons clear the path of astrocytic processes for their rapid migration in the adult brain. Neuron. 67: 213-23. PMID 20670830 DOI: 10.1016/J.Neuron.2010.06.018  0.698
2010 Sato T, Shimazaki T, Naka H, Fukami S, Satoh Y, Okano H, Lax I, Schlessinger J, Gotoh N. FRS2α regulates Erk levels to control a self-renewal target Hes1 and proliferation of FGF-responsive neural stem/progenitor cells. Stem Cells (Dayton, Ohio). 28: 1661-73. PMID 20652960 DOI: 10.1002/Stem.488  0.341
2010 Tsuji O, Miura K, Okada Y, Fujiyoshi K, Mukaino M, Nagoshi N, Kitamura K, Kumagai G, Nishino M, Tomisato S, Higashi H, Nagai T, Katoh H, Kohda K, Matsuzaki Y, ... ... Okano H, et al. Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury. Proceedings of the National Academy of Sciences of the United States of America. 107: 12704-9. PMID 20615974 DOI: 10.1073/Pnas.0910106107  0.353
2010 Mukaino M, Nakamura M, Yamada O, Okada S, Morikawa S, Renault-Mihara F, Iwanami A, Ikegami T, Ohsugi Y, Tsuji O, Katoh H, Matsuzaki Y, Toyama Y, Liu M, Okano H. Anti-IL-6-receptor antibody promotes repair of spinal cord injury by inducing microglia-dominant inflammation. Experimental Neurology. 224: 403-14. PMID 20478301 DOI: 10.1016/J.Expneurol.2010.04.020  0.3
2010 Contini M, Lin B, Kobayashi K, Okano H, Masland RH, Raviola E. Synaptic input of ON-bipolar cells onto the dopaminergic neurons of the mouse retina. The Journal of Comparative Neurology. 518: 2035-50. PMID 20394057 DOI: 10.1002/Cne.22320  0.325
2010 Kurihara T, Kubota Y, Ozawa Y, Takubo K, Noda K, Simon MC, Johnson RS, Suematsu M, Tsubota K, Ishida S, Goda N, Suda T, Okano H. von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina. Development (Cambridge, England). 137: 1563-71. PMID 20388654 DOI: 10.1242/Dev.049015  0.301
2010 Sakaguchi M, Imaizumi Y, Shingo T, Tada H, Hayama K, Yamada O, Morishita T, Kadoya T, Uchiyama N, Shimazaki T, Kuno A, Poirier F, Hirabayashi J, Sawamoto K, Okano H. Regulation of adult neural progenitor cells by Galectin-1/beta1 Integrin interaction. Journal of Neurochemistry. 113: 1516-24. PMID 20367753 DOI: 10.1111/J.1471-4159.2010.06712.X  0.752
2010 Yamane J, Nakamura M, Iwanami A, Sakaguchi M, Katoh H, Yamada M, Momoshima S, Miyao S, Ishii K, Tamaoki N, Nomura T, Okano HJ, Kanemura Y, Toyama Y, Okano H. Transplantation of galectin-1-expressing human neural stem cells into the injured spinal cord of adult common marmosets. Journal of Neuroscience Research. 88: 1394-405. PMID 20091712 DOI: 10.1002/Jnr.22322  0.531
2010 Kiyokage E, Pan YZ, Shao Z, Kobayashi K, Szabo G, Yanagawa Y, Obata K, Okano H, Toida K, Puche AC, Shipley MT. Molecular identity of periglomerular and short axon cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1185-96. PMID 20089927 DOI: 10.1523/Jneurosci.3497-09.2010  0.35
2010 Kojima T, Hirota Y, Ema M, Takahashi S, Miyoshi I, Okano H, Sawamoto K. Subventricular zone-derived neural progenitor cells migrate along a blood vessel scaffold toward the post-stroke striatum. Stem Cells (Dayton, Ohio). 28: 545-54. PMID 20073084 DOI: 10.1002/Stem.306  0.687
2010 Oki K, Kaneko N, Kanki H, Imai T, Suzuki N, Sawamoto K, Okano H. Musashi1 as a marker of reactive astrocytes after transient focal brain ischemia. Neuroscience Research. 66: 390-5. PMID 20036290 DOI: 10.1016/J.Neures.2009.12.013  0.707
2010 Ishii S, Okada Y, Kadoya T, Matsuzaki Y, Shimazaki T, Okano H. Stromal cell-secreted factors promote the survival of embryonic stem cell-derived early neural stem/progenitor cells via the activation of MAPK and PI3K-Akt pathways. Journal of Neuroscience Research. 88: 722-34. PMID 19798745 DOI: 10.1002/Jnr.22250  0.384
2010 Tao O, Shimazaki T, Okada Y, Naka H, Kohda K, Yuzaki M, Mizusawa H, Okano H. Efficient generation of mature cerebellar Purkinje cells from mouse embryonic stem cells. Journal of Neuroscience Research. 88: 234-47. PMID 19705453 DOI: 10.1002/Jnr.22208  0.361
2010 Suzuki A, Kuzumaki N, Narita M, Imai S, Okada Y, Okano JH, Okano H, Suzuki T, Narita M. Analysis of molecular mechanism underlying the control of ES cell differentiation by the stimulation of dopamine receptors located on embryonic stem cells Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.2166  0.343
2010 Kuzumaki N, Suzuki A, Narita M, Imai S, Okada Y, Okano JH, Okano H, Suzuki T, Narita M. Role of G-protein coupled receptors in the neural differentiation from embryonic stem cells Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.2165  0.354
2010 Kaneko N, Marin O, Koike M, Hirota Y, Uchiyama Y, Wu JY, Lu Q, Tessier-Lavigne M, Alvarez-Buylla A, Okano H, Rubenstein JL, Sawamoto K. New neurons form and maintain their path of astrocytic processes for rapid migration in the adult brain Neuroscience Research. 68: e93. DOI: 10.1016/J.Neures.2010.07.175  0.686
2010 Hirota Y, Meunier A, Huang S, Shimozawa T, Kida YS, Inoue M, Ito T, Kato H, Nakaya M, Nonaka S, Ogura T, Higuchi H, Okano H, Spassky N, Sawamoto K. Planar cell polarity of multiciliated ependymal cells regulated by non-muscle myosin II Neuroscience Research. 68: e364. DOI: 10.1016/J.Neures.2010.07.1614  0.67
2010 Hara K, Muto J, Kaneko N, Adachi K, Toyota F, Hikishima K, Itoh T, Sawamoto K, Kawase T, Yoshida K, Okano H. Development and analysis of less invasive transient middle cerebral artery occlusion model on Common Marmoset Neuroscience Research. 68: e320. DOI: 10.1016/J.Neures.2010.07.1418  0.628
2010 Ohta S, Kawakami Y, Okano H, Toda M. Functional analysis of macrophage migration inhibitory factor (MIF) in the mouse neural stem/progenitor cells Neuroscience Research. 68: e245-e246. DOI: 10.1016/J.Neures.2010.07.1088  0.351
2010 Ohta S, Kawakami Y, Okano H, Toda M. P45. Functional analysis of macrophage migration inhibitory factor (MIF) in the mouse neural stem/progenitor cells Differentiation. 80: S32. DOI: 10.1016/J.Diff.2010.09.051  0.363
2009 Nakashima K, Kohyama J, Namihira M, Gage FH, Okano H, Sawamoto K. [Epigenetic mechanisms regulating neural cell fate determination]. No to Hattatsu. Brain and Development. 41: 411-4. PMID 19928537  0.72
2009 Kumagai G, Okada Y, Yamane J, Nagoshi N, Kitamura K, Mukaino M, Tsuji O, Fujiyoshi K, Katoh H, Okada S, Shibata S, Matsuzaki Y, Toh S, Toyama Y, Nakamura M, ... Okano H, et al. Roles of ES cell-derived gliogenic neural stem/progenitor cells in functional recovery after spinal cord injury. Plos One. 4: e7706. PMID 19893739 DOI: 10.1371/Journal.Pone.0007706  0.336
2009 Tamase A, Muraguchi T, Naka K, Tanaka S, Kinoshita M, Hoshii T, Ohmura M, Shugo H, Ooshio T, Nakada M, Sawamoto K, Onodera M, Matsumoto K, Oshima M, Asano M, ... ... Okano H, et al. Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin. Proceedings of the National Academy of Sciences of the United States of America. 106: 17163-8. PMID 19805150 DOI: 10.1073/Pnas.0905016106  0.681
2009 Miura K, Okada Y, Aoi T, Okada A, Takahashi K, Okita K, Nakagawa M, Koyanagi M, Tanabe K, Ohnuki M, Ogawa D, Ikeda E, Okano H, Yamanaka S. Variation in the safety of induced pluripotent stem cell lines. Nature Biotechnology. 27: 743-5. PMID 19590502 DOI: 10.1038/Nbt.1554  0.362
2009 Horisawa K, Imai T, Okano H, Yanagawa H. 3'-Untranslated region of doublecortin mRNA is a binding target of the Musashi1 RNA-binding protein. Febs Letters. 583: 2429-34. PMID 19573529 DOI: 10.1016/J.Febslet.2009.06.045  0.311
2009 Oishia K, Watatani K, Itoh Y, Okano H, Guillemot F, Nakajima K, Gotoh Y. Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1 Proceedings of the National Academy of Sciences of the United States of America. 106: 13064-13069. PMID 19549840 DOI: 10.1073/Pnas.0808400106  0.37
2009 Tatsumi K, Tsuji S, Miwa H, Morisaku T, Nuriya M, Orihara M, Kaneko K, Okano H, Yasui M. Drosophila big brain does not act as a water channel, but mediates cell adhesion. Febs Letters. 583: 2077-82. PMID 19467350 DOI: 10.1016/J.Febslet.2009.05.035  0.35
2009 Okano H, Temple S. Cell types to order: temporal specification of CNS stem cells. Current Opinion in Neurobiology. 19: 112-9. PMID 19427192 DOI: 10.1016/J.Conb.2009.04.003  0.389
2009 Taura D, Noguchi M, Sone M, Hosoda K, Mori E, Okada Y, Takahashi K, Homma K, Oyamada N, Inuzuka M, Sonoyama T, Ebihara K, Tamura N, Itoh H, Suemori H, ... ... Okano H, et al. Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells. Febs Letters. 583: 1029-33. PMID 19250937 DOI: 10.1016/J.Febslet.2009.02.031  0.347
2009 Akamatsu W, DeVeale B, Okano H, Cooney AJ, van der Kooy D. Suppression of Oct4 by germ cell nuclear factor restricts pluripotency and promotes neural stem cell development in the early neural lineage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2113-24. PMID 19228964 DOI: 10.1523/Jneurosci.4527-08.2009  0.368
2009 Ogawa D, Okada Y, Nakamura M, Kanemura Y, Okano HJ, Matsuzaki Y, Shimazaki T, Ito M, Ikeda E, Tamiya T, Nagao S, Okano H. Evaluation of human fetal neural stem/progenitor cells as a source for cell replacement therapy for neurological disorders: properties and tumorigenicity after long-term in vitro maintenance. Journal of Neuroscience Research. 87: 307-17. PMID 18972448 DOI: 10.1002/Jnr.21843  0.332
2009 Yajima M, Kuzumaki N, Narita M, Narita M, Imai S, Okada Y, Okano JH, Okano H, Suzuki T. P2-a15Promotion of the neural differentiation from embryonic stem cells activated by dopamine D3 receptors Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.677  0.325
2009 Kuzumaki N, Narita M, Yajima M, Narita M, Imai S, Furuta S, Okada Y, Okano JH, Okano H, Suzuki T. Possible implication of μ-opioid receptors in the neural differentiation from embryonic stem cells Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.676  0.33
2009 Ohta S, Kawakami Y, Okano H, Kawase T, Toda M. Macrophage migration inhibitory factor (MIF) promotes proliferation and cell survival of neural stem/progenitor cells Neuroscience Research. 65: S91. DOI: 10.1016/J.Neures.2009.09.375  0.359
2009 Ikeda M, Hirota Y, Sakaguchi M, Yamada O, Kida Y, Ogura T, Otsuka T, Okano H, Sawamoto K. Role of Diversin as a possible switch of distinct Wnt pathways regulating multiple steps of adult neurogenesis Neuroscience Research. 65: S54. DOI: 10.1016/J.Neures.2009.09.129  0.728
2009 Hirota Y, Huang S, Yamada O, Kida Y, Ogura T, Spassky N, Nonaka S, Okano H, Sawamoto K. Planar polarity decisions for directional beating of ependymal cilia and fluid flow in the adult mouse lateral ventricles Neuroscience Research. 65: S54. DOI: 10.1016/J.Neures.2009.09.127  0.645
2008 Naka H, Nakamura S, Shimazaki T, Okano H. Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development. Nature Neuroscience. 11: 1014-23. PMID 19160499 DOI: 10.1038/Nn.2168  0.411
2008 Kohyama J, Kojima T, Takatsuka E, Yamashita T, Namiki J, Hsieh J, Gage FH, Namihira M, Okano H, Sawamoto K, Nakashima K. Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain. Proceedings of the National Academy of Sciences of the United States of America. 105: 18012-7. PMID 19004774 DOI: 10.1073/Pnas.0808417105  0.746
2008 Okada Y, Matsumoto A, Shimazaki T, Enoki R, Koizumi A, Ishii S, Itoyama Y, Sobue G, Okano H. Spatiotemporal recapitulation of central nervous system development by murine embryonic stem cell-derived neural stem/progenitor cells. Stem Cells (Dayton, Ohio). 26: 3086-98. PMID 18757299 DOI: 10.1634/Stemcells.2008-0293  0.405
2008 Miyagi S, Masui S, Niwa H, Saito T, Shimazaki T, Okano H, Nishimoto M, Muramatsu M, Iwama A, Okuda A. Consequence of the loss of Sox2 in the developing brain of the mouse. Febs Letters. 582: 2811-5. PMID 18638478 DOI: 10.1016/J.Febslet.2008.07.011  0.383
2008 Valentin-Vega YA, Okano H, Lozano G. The intestinal epithelium compensates for p53-mediated cell death and guarantees organismal survival. Cell Death and Differentiation. 15: 1772-81. PMID 18636077 DOI: 10.1038/Cdd.2008.109  0.34
2008 Ozawa Y, Nakao K, Kurihara T, Shimazaki T, Shimmura S, Ishida S, Yoshimura A, Tsubota K, Okano H. Roles of STAT3/SOCS3 pathway in regulating the visual function and ubiquitin-proteasome-dependent degradation of rhodopsin during retinal inflammation. The Journal of Biological Chemistry. 283: 24561-70. PMID 18614536 DOI: 10.1074/Jbc.M802238200  0.313
2008 Kanaya T, Miyazawa K, Takakura I, Itani W, Watanabe K, Ohwada S, Kitazawa H, Rose MT, McConochie HR, Okano H, Yamaguchi T, Aso H. Differentiation of a murine intestinal epithelial cell line (MIE) toward the M cell lineage. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G273-84. PMID 18556421 DOI: 10.1152/Ajpgi.00378.2007  0.324
2008 Sato Y, Watanabe T, Saito D, Takahashi T, Yoshida S, Kohyama J, Ohata E, Okano H, Takahashi Y. Notch mediates the segmental specification of angioblasts in somites and their directed migration toward the dorsal aorta in avian embryos. Developmental Cell. 14: 890-901. PMID 18539117 DOI: 10.1016/J.Devcel.2008.03.024  0.357
2008 Deguchi K, Clewing JM, Elizondo LI, Hirano R, Huang C, Choi K, Sloan EA, Lücke T, Marwedel KM, Powell RD, Santa Cruz K, Willaime-Morawek S, Inoue K, Lou S, Northrop JL, ... ... Okano H, et al. Neurologic phenotype of Schimke immuno-osseous dysplasia and neurodevelopmental expression of SMARCAL1. Journal of Neuropathology and Experimental Neurology. 67: 565-77. PMID 18520775 DOI: 10.1097/Nen.0B013E3181772777  0.359
2008 Kawahara H, Imai T, Imataka H, Tsujimoto M, Matsumoto K, Okano H. Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP. The Journal of Cell Biology. 181: 639-53. PMID 18490513 DOI: 10.1083/Jcb.200708004  0.331
2008 Nagoshi N, Shibata S, Kubota Y, Nakamura M, Nagai Y, Satoh E, Morikawa S, Okada Y, Mabuchi Y, Katoh H, Okada S, Fukuda K, Suda T, Matsuzaki Y, Toyama Y, ... Okano H, et al. Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad. Cell Stem Cell. 2: 392-403. PMID 18397758 DOI: 10.1016/J.Stem.2008.03.005  0.393
2008 Wang XY, Yin Y, Yuan H, Sakamaki T, Okano H, Glazer RI. Musashi1 modulates mammary progenitor cell expansion through proliferin-mediated activation of the Wnt and Notch pathways. Molecular and Cellular Biology. 28: 3589-99. PMID 18362162 DOI: 10.1128/Mcb.00040-08  0.389
2008 Sunabori T, Tokunaga A, Nagai T, Sawamoto K, Okabe M, Miyawaki A, Matsuzaki Y, Miyata T, Okano H. Cell-cycle-specific nestin expression coordinates with morphological changes in embryonic cortical neural progenitors. Journal of Cell Science. 121: 1204-12. PMID 18349072 DOI: 10.1242/Jcs.025064  0.779
2008 Okano H, Sawamoto K. Neural stem cells: involvement in adult neurogenesis and CNS repair. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 363: 2111-22. PMID 18339601 DOI: 10.1098/Rstb.2008.2264  0.723
2008 Ma D, Lu L, Boneva NB, Warashina S, Kaplamadzhiev DB, Mori Y, Nakaya MA, Kikuchi M, Tonchev AB, Okano H, Yamashima T. Expression of free fatty acid receptor GPR40 in the neurogenic niche of adult monkey hippocampus. Hippocampus. 18: 326-33. PMID 18064707 DOI: 10.1002/Hipo.20393  0.377
2008 Ohta S, Ueda Y, Yaguchi M, Matsuzaki Y, Nakamura M, Toyama Y, Tanioka Y, Tamaoki N, Nomura T, Okano H, Kawakami Y, Toda M. Isolation and characterization of dendritic cells from common marmosets for preclinical cell therapy studies. Immunology. 123: 566-74. PMID 18005037 DOI: 10.1111/J.1365-2567.2007.02727.X  0.306
2008 Murata H, Tsuji S, Tsujii M, Nakamura T, Fu HY, Eguchi H, Asahi K, Okano H, Kawano S, Hayashi N. Helicobacter pylori infection induces candidate stem cell marker Musashi-1 in the human gastric epithelium. Digestive Diseases and Sciences. 53: 363-9. PMID 17549630 DOI: 10.1007/S10620-007-9858-5  0.344
2007 Hirota Y, Ohshima T, Kaneko N, Ikeda M, Iwasato T, Kulkarni AB, Mikoshiba K, Okano H, Sawamoto K. Cyclin-dependent kinase 5 is required for control of neuroblast migration in the postnatal subventricular zone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12829-38. PMID 18032654 DOI: 10.1523/Jneurosci.1014-07.2007  0.7
2007 Hattori Y, Ohta S, Hamada K, Yamada-Okabe H, Kanemura Y, Matsuzaki Y, Okano H, Kawakami Y, Toda M. Identification of a neuron-specific human gene, KIAA1110, that is a guanine nucleotide exchange factor for ARF1. Biochemical and Biophysical Research Communications. 364: 737-42. PMID 17981261 DOI: 10.1016/J.Bbrc.2007.10.041  0.398
2007 Ishibashi S, Kuroiwa T, Sakaguchi M, Sun L, Kadoya T, Okano H, Mizusawa H. Galectin-1 regulates neurogenesis in the subventricular zone and promotes functional recovery after stroke. Experimental Neurology. 207: 302-13. PMID 17706645 DOI: 10.1016/J.Expneurol.2007.06.024  0.574
2007 Okano H, Sakaguchi M, Ohki K, Suzuki N, Sawamoto K. Regeneration of the central nervous system using endogenous repair mechanisms. Journal of Neurochemistry. 102: 1459-65. PMID 17697047 DOI: 10.1111/J.1471-4159.2007.04674.X  0.761
2007 Adachi K, Mirzadeh Z, Sakaguchi M, Yamashita T, Nikolcheva T, Gotoh Y, Peltz G, Gong L, Kawase T, Alvarez-Buylla A, Okano H, Sawamoto K. Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone. Stem Cells (Dayton, Ohio). 25: 2827-36. PMID 17673525 DOI: 10.1634/Stemcells.2007-0177  0.772
2007 Imai N, Hishikawa K, Marumo T, Hirahashi J, Inowa T, Matsuzaki Y, Okano H, Kitamura T, Salant D, Fujita T. Inhibition of histone deacetylase activates side population cells in kidney and partially reverses chronic renal injury. Stem Cells (Dayton, Ohio). 25: 2469-75. PMID 17641247 DOI: 10.1634/Stemcells.2007-0049  0.307
2007 Bolognani F, Tanner DC, Nixon S, Okano HJ, Okano H, Perrone-Bizzozero NI. Coordinated expression of HuD and GAP-43 in hippocampal dentate granule cells during developmental and adult plasticity. Neurochemical Research. 32: 2142-51. PMID 17577668 DOI: 10.1007/S11064-007-9388-8  0.342
2007 Iijima T, Ogura H, Takatsuki K, Kawahara S, Wakabayashi K, Nakayama D, Fujioka M, Kimura Y, Bernstein A, Okano HJ, Kirino Y, Okano H. Impaired motor functions in mice lacking the RNA-binding protein Hzf. Neuroscience Research. 58: 183-9. PMID 17383763 DOI: 10.1016/J.Neures.2007.02.013  0.328
2007 Sakaguchi M, Imaizumi Y, Okano H. Expression and function of galectin-1 in adult neural stem cells. Cellular and Molecular Life Sciences : Cmls. 64: 1254-8. PMID 17364145 DOI: 10.1007/S00018-007-6476-5  0.576
2007 Hayakawa-Yano Y, Nishida K, Fukami S, Gotoh Y, Hirano T, Nakagawa T, Shimazaki T, Okano H. Epidermal growth factor signaling mediated by grb2 associated binder1 is required for the spatiotemporally regulated proliferation of olig2-expressing progenitors in the embryonic spinal cord. Stem Cells (Dayton, Ohio). 25: 1410-22. PMID 17332510 DOI: 10.1634/Stemcells.2006-0584  0.336
2007 Kohno D, Nakata M, Maekawa F, Fujiwara K, Maejima Y, Kuramochi M, Shimazaki T, Okano H, Onaka T, Yada T. Leptin suppresses ghrelin-induced activation of neuropeptide Y neurons in the arcuate nucleus via phosphatidylinositol 3-kinase- and phosphodiesterase 3-mediated pathway. Endocrinology. 148: 2251-63. PMID 17303662 DOI: 10.1210/En.2006-1240  0.312
2007 Masuda H, Maruyama T, Hiratsu E, Yamane J, Iwanami A, Nagashima T, Ono M, Miyoshi H, Okano HJ, Ito M, Tamaoki N, Nomura T, Okano H, Matsuzaki Y, Yoshimura Y. Noninvasive and real-time assessment of reconstructed functional human endometrium in NOD/SCID/gamma c(null) immunodeficient mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 1925-30. PMID 17261813 DOI: 10.1073/Pnas.0604310104  0.323
2007 Kanai R, Tomita H, Hirose Y, Ohba S, Goldman S, Okano H, Kawase T, Yazaki T. Augmented therapeutic efficacy of an oncolytic herpes simplex virus type 1 mutant expressing ICP34.5 under the transcriptional control of musashi1 promoter in the treatment of malignant glioma. Human Gene Therapy. 18: 63-73. PMID 17238803 DOI: 10.1089/Hum.2006.107  0.315
2007 Ozawa Y, Nakao K, Shimazaki T, Shimmura S, Kurihara T, Ishida S, Yoshimura A, Tsubota K, Okano H. SOCS3 is required to temporally fine-tune photoreceptor cell differentiation. Developmental Biology. 303: 591-600. PMID 17198696 DOI: 10.1016/J.Ydbio.2006.11.032  0.356
2007 Ohta S, Okano H, Kawase T, Toda M. Sox6 is expressed in mouse embryonic neural stem/progenitor cells (NSPCs) and contributes to their maintenance and/or survival Neuroscience Research. 58: S199. DOI: 10.1016/J.Neures.2007.06.896  0.369
2007 Nakashima K, Takatsuka E, Yamashita T, Hsieh J, Gage FH, Namihira M, Okano H, Sawamoto K, Kohyama J. Epigenetic mechanism regulating fate specification and plasticity of neural cells Neuroscience Research. 58. DOI: 10.1016/J.Neures.2007.06.108  0.703
2006 Yamashita T, Deguchi K, Sawamoto K, Okano H, Kamiya T, Abe K. Neuroprotection and neurosupplementation in ischaemic brain. Biochemical Society Transactions. 34: 1310-2. PMID 17073809 DOI: 10.1042/Bst0341310  0.691
2006 Ishii K, Nakamura M, Dai H, Finn TP, Okano H, Toyama Y, Bregman BS. Neutralization of ciliary neurotrophic factor reduces astrocyte production from transplanted neural stem cells and promotes regeneration of corticospinal tract fibers in spinal cord injury. Journal of Neuroscience Research. 84: 1669-81. PMID 17044031 DOI: 10.1002/Jnr.21079  0.326
2006 Kaneko N, Okano H, Sawamoto K. Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 11: 1145-59. PMID 16999735 DOI: 10.1111/J.1365-2443.2006.01010.X  0.709
2006 Yamashima T, Popivanova BK, Guo J, Kotani S, Wakayama T, Iseki S, Sawamoto K, Okano H, Fujii C, Mukaida N, Tonchev AB. Implication of "Down syndrome cell adhesion molecule" in the hippocampal neurogenesis of ischemic monkeys. Hippocampus. 16: 924-35. PMID 16983647 DOI: 10.1002/Hipo.20223  0.731
2006 Sasaki T, Kitagawa K, Yagita Y, Sugiura S, Omura-Matsuoka E, Tanaka S, Matsushita K, Okano H, Tsujimoto Y, Hori M. Bcl2 enhances survival of newborn neurons in the normal and ischemic hippocampus. Journal of Neuroscience Research. 84: 1187-96. PMID 16941650 DOI: 10.1002/Jnr.21036  0.345
2006 Arata Y, Kouike H, Zhang Y, Herman MA, Okano H, Sawa H. Wnt signaling and a Hox protein cooperatively regulate psa-3/Meis to determine daughter cell fate after asymmetric cell division in C. elegans. Developmental Cell. 11: 105-15. PMID 16824957 DOI: 10.1016/J.Devcel.2006.04.020  0.38
2006 Okada S, Nakamura M, Katoh H, Miyao T, Shimazaki T, Ishii K, Yamane J, Yoshimura A, Iwamoto Y, Toyama Y, Okano H. Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury. Nature Medicine. 12: 829-34. PMID 16783372 DOI: 10.1038/Nm1425  0.317
2006 Chan C, Moore BE, Cotman CW, Okano H, Tavares R, Hovanesian V, Pinar H, Johanson CE, Svendsen CN, Stopa EG. Musashi1 antigen expression in human fetal germinal matrix development. Experimental Neurology. 201: 515-8. PMID 16777095 DOI: 10.1016/J.Expneurol.2006.04.023  0.383
2006 Yamashita T, Ninomiya M, Hernández Acosta P, García-Verdugo JM, Sunabori T, Sakaguchi M, Adachi K, Kojima T, Hirota Y, Kawase T, Araki N, Abe K, Okano H, Sawamoto K. Subventricular zone-derived neuroblasts migrate and differentiate into mature neurons in the post-stroke adult striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6627-36. PMID 16775151 DOI: 10.1523/Jneurosci.0149-06.2006  0.779
2006 Ninomiya M, Yamashita T, Araki N, Okano H, Sawamoto K. Enhanced neurogenesis in the ischemic striatum following EGF-induced expansion of transit-amplifying cells in the subventricular zone. Neuroscience Letters. 403: 63-7. PMID 16701951 DOI: 10.1016/J.Neulet.2006.04.039  0.717
2006 Sakaguchi M, Shingo T, Shimazaki T, Okano HJ, Shiwa M, Ishibashi S, Oguro H, Ninomiya M, Kadoya T, Horie H, Shibuya A, Mizusawa H, Poirier F, Nakauchi H, Sawamoto K, ... Okano H, et al. A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 7112-7. PMID 16636291 DOI: 10.1073/Pnas.0508793103  0.771
2006 Tonchev AB, Yamashima T, Sawamoto K, Okano H. Transcription factor protein expression patterns by neural or neuronal progenitor cells of adult monkey subventricular zone. Neuroscience. 139: 1355-67. PMID 16580139 DOI: 10.1016/J.Neuroscience.2006.01.053  0.748
2006 Miyagi S, Nishimoto M, Saito T, Ninomiya M, Sawamoto K, Okano H, Muramatsu M, Oguro H, Iwama A, Okuda A. The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon. The Journal of Biological Chemistry. 281: 13374-81. PMID 16547000 DOI: 10.1074/Jbc.M512669200  0.726
2006 Rawal N, Castelo-Branco G, Sousa KM, Kele J, Kobayashi K, Okano H, Arenas E. Dynamic temporal and cell type-specific expression of Wnt signaling components in the developing midbrain. Experimental Cell Research. 312: 1626-36. PMID 16510140 DOI: 10.1016/J.Yexcr.2006.01.032  0.376
2006 Toriya M, Tokunaga A, Sawamoto K, Nakao K, Okano H. Distinct functions of human numb isoforms revealed by misexpression in the neural stem cell lineage in the Drosophila larval brain. Developmental Neuroscience. 28: 142-55. PMID 16508311 DOI: 10.1159/000090760  0.747
2006 Sawamoto K, Wichterle H, Gonzalez-Perez O, Cholfin JA, Yamada M, Spassky N, Murcia NS, Garcia-Verdugo JM, Marin O, Rubenstein JL, Tessier-Lavigne M, Okano H, Alvarez-Buylla A. New neurons follow the flow of cerebrospinal fluid in the adult brain. Science (New York, N.Y.). 311: 629-32. PMID 16410488 DOI: 10.1126/Science.1119133  0.689
2006 Fukuhara Y, Li XK, Kitazawa Y, Inagaki M, Matsuoka K, Kosuga M, Kosaki R, Shimazaki T, Endo H, Umezawa A, Okano H, Takahashi T, Okuyama T. Histopathological and behavioral improvement of murine mucopolysaccharidosis type VII by intracerebral transplantation of neural stem cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 548-55. PMID 16316785 DOI: 10.1016/J.Ymthe.2005.09.020  0.339
2005 Ikegami T, Nakamura M, Yamane J, Katoh H, Okada S, Iwanami A, Watanabe K, Ishii K, Kato F, Fujita H, Takahashi T, Okano HJ, Toyama Y, Okano H. Chondroitinase ABC combined with neural stem/progenitor cell transplantation enhances graft cell migration and outgrowth of growth-associated protein-43-positive fibers after rat spinal cord injury. The European Journal of Neuroscience. 22: 3036-46. PMID 16367770 DOI: 10.1111/J.1460-9568.2005.04492.X  0.301
2005 Asai R, Okano H, Yasugi S. Correlation between Musashi-1 and c-hairy-1 expression and cell proliferation activity in the developing intestine and stomach of both chicken and mouse. Development, Growth & Differentiation. 47: 501-10. PMID 16287482 DOI: 10.1111/J.1440-169X.2005.00825.X  0.384
2005 Kanuka H, Hiratou T, Igaki T, Kanda H, Kuranaga E, Sawamoto K, Aigaki T, Okano H, Miura M. Gain-of-function screen identifies a role of the Sec61alpha translocon in Drosophila postmitotic neurotoxicity. Biochimica Et Biophysica Acta. 1726: 225-37. PMID 16243437 DOI: 10.1016/J.Bbagen.2005.06.020  0.726
2005 Yamamoto S, Yoshino I, Shimazaki T, Murohashi M, Hevner RF, Lax I, Okano H, Shibuya M, Schlessinger J, Gotoh N. Essential role of Shp2-binding sites on FRS2alpha for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 15983-8. PMID 16239343 DOI: 10.1073/Pnas.0507961102  0.449
2005 Suzuki T, Izumoto S, Wada K, Fujimoto Y, Maruno M, Yamasaki M, Kanemura Y, Shimazaki T, Okano H, Yoshimine T. Inhibition of glioma cell proliferation by neural stem cell factor. Journal of Neuro-Oncology. 74: 233-9. PMID 16187020 DOI: 10.1007/S11060-004-7118-5  0.374
2005 Tomita Y, Matsumura K, Wakamatsu Y, Matsuzaki Y, Shibuya I, Kawaguchi H, Ieda M, Kanakubo S, Shimazaki T, Ogawa S, Osumi N, Okano H, Fukuda K. Cardiac neural crest cells contribute to the dormant multipotent stem cell in the mammalian heart. The Journal of Cell Biology. 170: 1135-46. PMID 16186259 DOI: 10.1083/Jcb.200504061  0.397
2005 Kohyama J, Tokunaga A, Fujita Y, Miyoshi H, Nagai T, Miyawaki A, Nakao K, Matsuzaki Y, Okano H. Visualization of spatiotemporal activation of Notch signaling: live monitoring and significance in neural development. Developmental Biology. 286: 311-25. PMID 16153632 DOI: 10.1016/J.Ydbio.2005.08.003  0.36
2005 Okada S, Ishii K, Yamane J, Iwanami A, Ikegami T, Katoh H, Iwamoto Y, Nakamura M, Miyoshi H, Okano HJ, Contag CH, Toyama Y, Okano H. In vivo imaging of engrafted neural stem cells: its application in evaluating the optimal timing of transplantation for spinal cord injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1839-41. PMID 16141363 DOI: 10.1096/Fj.05-4082Fje  0.316
2005 Sasaki E, Hanazawa K, Kurita R, Akatsuka A, Yoshizaki T, Ishii H, Tanioka Y, Ohnishi Y, Suemizu H, Sugawara A, Tamaoki N, Izawa K, Nakazaki Y, Hamada H, Suemori H, ... ... Okano H, et al. Establishment of novel embryonic stem cell lines derived from the common marmoset (Callithrix jacchus). Stem Cells (Dayton, Ohio). 23: 1304-13. PMID 16109758 DOI: 10.1634/Stemcells.2004-0366  0.329
2005 Tonchev AB, Yamashima T, Sawamoto K, Okano H. Enhanced proliferation of progenitor cells in the subventricular zone and limited neuronal production in the striatum and neocortex of adult macaque monkeys after global cerebral ischemia. Journal of Neuroscience Research. 81: 776-88. PMID 16047371 DOI: 10.1002/Jnr.20604  0.728
2005 Crespel A, Rigau V, Coubes P, Rousset MC, de Bock F, Okano H, Baldy-Moulinier M, Bockaert J, Lerner-Natoli M. Increased number of neural progenitors in human temporal lobe epilepsy. Neurobiology of Disease. 19: 436-50. PMID 16023586 DOI: 10.1016/J.Nbd.2005.01.020  0.378
2005 Yamashita T, Sawamoto K, Suzuki S, Suzuki N, Adachi K, Kawase T, Mihara M, Ohsugi Y, Abe K, Okano H. Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons. Journal of Neurochemistry. 94: 459-68. PMID 15998296 DOI: 10.1111/J.1471-4159.2005.03227.X  0.654
2005 Hishikawa K, Marumo T, Miura S, Nakanishi A, Matsuzaki Y, Shibata K, Ichiyanagi T, Kohike H, Komori T, Takahashi I, Takase O, Imai N, Yoshikawa M, Inowa T, Hayashi M, ... ... Okano H, et al. Musculin/MyoR is expressed in kidney side population cells and can regulate their function. The Journal of Cell Biology. 169: 921-8. PMID 15967813 DOI: 10.1083/Jcb.200412167  0.335
2005 Jomphe C, Bourque MJ, Fortin GD, St-Gelais F, Okano H, Kobayashi K, Trudeau LE. Use of TH-EGFP transgenic mice as a source of identified dopaminergic neurons for physiological studies in postnatal cell culture. Journal of Neuroscience Methods. 146: 1-12. PMID 15935217 DOI: 10.1016/J.Jneumeth.2005.01.014  0.373
2005 Uchida K, Momiyama T, Okano H, Yuzaki M, Koizumi A, Mine Y, Kawase T. Potential functional neural repair with grafted neural stem cells of early embryonic neuroepithelial origin. Neuroscience Research. 52: 276-86. PMID 15927727 DOI: 10.1016/J.Neures.2005.03.015  0.385
2005 Okano H, Kawahara H, Toriya M, Nakao K, Shibata S, Imai T. Function of RNA-binding protein Musashi-1 in stem cells. Experimental Cell Research. 306: 349-56. PMID 15925591 DOI: 10.1016/J.Yexcr.2005.02.021  0.391
2005 Yoshimi K, Ren YR, Seki T, Yamada M, Ooizumi H, Onodera M, Saito Y, Murayama S, Okano H, Mizuno Y, Mochizuki H. Possibility for neurogenesis in substantia nigra of parkinsonian brain. Annals of Neurology. 58: 31-40. PMID 15912513 DOI: 10.1002/Ana.20506  0.347
2005 Yuasa S, Itabashi Y, Koshimizu U, Tanaka T, Sugimura K, Kinoshita M, Hattori F, Fukami S, Shimazaki T, Ogawa S, Okano H, Fukuda K. Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells. Nature Biotechnology. 23: 607-11. PMID 15867910 DOI: 10.1038/Nbt1093  0.364
2005 Kambara H, Okano H, Chiocca EA, Saeki Y. An oncolytic HSV-1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals even when symptomatic from a brain tumor. Cancer Research. 65: 2832-9. PMID 15805284 DOI: 10.1158/0008-5472.Can-04-3227  0.325
2005 Nagato M, Heike T, Kato T, Yamanaka Y, Yoshimoto M, Shimazaki T, Okano H, Nakahata T. Prospective characterization of neural stem cells by flow cytometry analysis using a combination of surface markers. Journal of Neuroscience Research. 80: 456-66. PMID 15795928 DOI: 10.1002/Jnr.20442  0.394
2005 Suzuki S, Yamashita T, Tanaka K, Hattori H, Sawamoto K, Okano H, Suzuki N. Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 685-93. PMID 15716858 DOI: 10.1038/Sj.Jcbfm.9600061  0.66
2005 Kitagawa A, Nakayama T, Takenaga M, Matsumoto K, Tokura Y, Ohta Y, Ichinohe M, Yamaguchi Y, Suzuki N, Okano H, Igarashi R. Lecithinized brain-derived neurotrophic factor promotes the differentiation of embryonic stem cells in vitro and in vivo. Biochemical and Biophysical Research Communications. 328: 1051-7. PMID 15707984 DOI: 10.1016/J.Bbrc.2005.01.063  0.348
2005 Uemura O, Okada Y, Ando H, Guedj M, Higashijima S, Shimazaki T, Chino N, Okano H, Okamoto H. Comparative functional genomics revealed conservation and diversification of three enhancers of the isl1 gene for motor and sensory neuron-specific expression. Developmental Biology. 278: 587-606. PMID 15680372 DOI: 10.1016/J.Ydbio.2004.11.031  0.339
2005 Suzuki K, Fukui H, Kayahara T, Sawada M, Seno H, Hiai H, Kageyama R, Okano H, Chiba T. Hes1-deficient mice show precocious differentiation of Paneth cells in the small intestine. Biochemical and Biophysical Research Communications. 328: 348-52. PMID 15670790 DOI: 10.1016/J.Bbrc.2004.12.174  0.337
2005 Hishikawa K, Marumo T, Miura S, Nakanishi A, Matsuzaki Y, Shibata K, Kohike H, Komori T, Hayashi M, Nakaki T, Nakauchi H, Okano H, Fujita T. Leukemia inhibitory factor induces multi-lineage differentiation of adult stem-like cells in kidney via kidney-specific cadherin 16. Biochemical and Biophysical Research Communications. 328: 288-91. PMID 15670782 DOI: 10.1016/J.Bbrc.2004.12.167  0.353
2005 Hirota Y, Sawamoto K, Takahashi K, Ueda R, Okano H. The transmembrane protein, Tincar, is involved in the development of the compound eye in Drosophila melanogaster. Development Genes and Evolution. 215: 90-6. PMID 15654626 DOI: 10.1007/S00427-004-0452-Y  0.703
2005 Clarke RB, Spence K, Anderson E, Howell A, Okano H, Potten CS. A putative human breast stem cell population is enriched for steroid receptor-positive cells Developmental Biology. 277: 443-456. PMID 15617686 DOI: 10.1016/J.Ydbio.2004.07.044  0.361
2005 Sakaguchi M, Sawamoto K, Shimazaki T, Kitamura T, Shibuya A, Okano H. A method for gene transfer, single isolation and in vitro assay for neural stem cells Ensho Saisei. 25: 50-54. DOI: 10.2492/Jsir.25.50  0.748
2004 Hori K, Fostier M, Ito M, Fuwa TJ, Go MJ, Okano H, Baron M, Matsuno K. Drosophila deltex mediates suppressor of Hairless-independent and late-endosomal activation of Notch signaling. Development (Cambridge, England). 131: 5527-37. PMID 15496440 DOI: 10.1242/Dev.01448  0.763
2004 Okada Y, Shimazaki T, Sobue G, Okano H. Retinoic-acid-concentration-dependent acquisition of neural cell identity during in vitro differentiation of mouse embryonic stem cells. Developmental Biology. 275: 124-42. PMID 15464577 DOI: 10.1016/J.Ydbio.2004.07.038  0.338
2004 Yamashima T, Tonchev AB, Vachkov IH, Popivanova BK, Seki T, Sawamoto K, Okano H. Vascular adventitia generates neuronal progenitors in the monkey hippocampus after ischemia. Hippocampus. 14: 861-75. PMID 15382256 DOI: 10.1002/Hipo.20001  0.715
2004 Ishibashi S, Sakaguchi M, Kuroiwa T, Yamasaki M, Kanemura Y, Shizuko I, Shimazaki T, Onodera M, Okano H, Mizusawa H. Human neural stem/progenitor cells, expanded in long-term neurosphere culture, promote functional recovery after focal ischemia in Mongolian gerbils. Journal of Neuroscience Research. 78: 215-23. PMID 15378509 DOI: 10.1002/Jnr.20246  0.556
2004 Unezaki S, Nishizawa M, Okuda-Ashitaka E, Masu Y, Mukai M, Kobayashi S, Sawamoto K, Okano H, Ito S. Characterization of the isoforms of MOVO zinc finger protein, a mouse homologue of Drosophila Ovo, as transcription factors. Gene. 336: 47-58. PMID 15225875 DOI: 10.1016/J.Gene.2004.03.013  0.677
2004 Ozawa Y, Nakao K, Shimazaki T, Takeda J, Akira S, Ishihara K, Hirano T, Oguchi Y, Okano H. Downregulation of STAT3 activation is required for presumptive rod photoreceptor cells to differentiate in the postnatal retina. Molecular and Cellular Neurosciences. 26: 258-70. PMID 15207851 DOI: 10.2492/Jsir.25.118  0.331
2004 Tokunaga A, Kohyama J, Yoshida T, Nakao K, Sawamoto K, Okano H. Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain. Journal of Neurochemistry. 90: 142-54. PMID 15198674 DOI: 10.1111/J.1471-4159.2004.02470.X  0.72
2004 Yoshizaki T, Inaji M, Kouike H, Shimazaki T, Sawamoto K, Ando K, Date I, Kobayashi K, Suhara T, Uchiyama Y, Okano H. Isolation and transplantation of dopaminergic neurons generated from mouse embryonic stem cells. Neuroscience Letters. 363: 33-7. PMID 15157991 DOI: 10.1016/J.Neulet.2004.03.074  0.72
2004 Mikami Y, Okano H, Sakaguchi M, Nakamura M, Shimazaki T, Okano HJ, Kawakami Y, Toyama Y, Toda M. Implantation of dendritic cells in injured adult spinal cord results in activation of endogenous neural stem/progenitor cells leading to de novo neurogenesis and functional recovery. Journal of Neuroscience Research. 76: 453-65. PMID 15114617 DOI: 10.1002/Jnr.20086  0.528
2004 Ieda M, Fukuda K, Hisaka Y, Kimura K, Kawaguchi H, Fujita J, Shimoda K, Takeshita E, Okano H, Kurihara Y, Kurihara H, Ishida J, Fukamizu A, Federoff HJ, Ogawa S. Endothelin-1 regulates cardiac sympathetic innervation in the rodent heart by controlling nerve growth factor expression. The Journal of Clinical Investigation. 113: 876-84. PMID 15067320 DOI: 10.1172/Jci19480  0.306
2004 Okada S, Nakamura M, Mikami Y, Shimazaki T, Mihara M, Ohsugi Y, Iwamoto Y, Yoshizaki K, Kishimoto T, Toyama Y, Okano H. Blockade of interleukin-6 receptor suppresses reactive astrogliosis and ameliorates functional recovery in experimental spinal cord injury. Journal of Neuroscience Research. 76: 265-76. PMID 15048924 DOI: 10.1002/Jnr.20044  0.309
2004 Ohba H, Chiyoda T, Endo E, Yano M, Hayakawa Y, Sakaguchi M, Darnell RB, Okano HJ, Okano H. Sox21 is a repressor of neuronal differentiation and is antagonized by YB-1. Neuroscience Letters. 358: 157-60. PMID 15039105 DOI: 10.1016/J.Neulet.2004.01.026  0.589
2004 Matsuzaki Y, Kinjo K, Mulligan RC, Okano H. Unexpectedly efficient homing capacity of purified murine hematopoietic stem cells. Immunity. 20: 87-93. PMID 14738767 DOI: 10.1016/S1074-7613(03)00354-6  0.336
2004 Kambara H, Okano H, Chiocca EA, Saeki Y. 624. Effect of an Oncolytic HSV Mutant Expressing ICP34.5 under Control of a Nestin Promoter for Brain Tumor Therapy Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.548  0.36
2003 Hu QD, Ang BT, Karsak M, Hu WP, Cui XY, Duka T, Takeda Y, Chia W, Sankar N, Ng YK, Ling EA, Maciag T, Small D, Trifonova R, Kopan R, ... Okano H, et al. F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation. Cell. 115: 163-75. PMID 14567914 DOI: 10.1016/S0092-8674(03)00810-9  0.329
2003 Kokuzawa J, Yoshimura S, Kitajima H, Shinoda J, Kaku Y, Iwama T, Morishita R, Shimazaki T, Okano H, Kunisada T, Sakai N. Hepatocyte growth factor promotes proliferation and neuronal differentiation of neural stem cells from mouse embryos. Molecular and Cellular Neurosciences. 24: 190-7. PMID 14550779 DOI: 10.1016/S1044-7431(03)00160-X  0.413
2003 Kanuka H, Kuranaga E, Hiratou T, Igaki T, Nelson B, Okano H, Miura M. Cytosol-endoplasmic reticulum interplay by Sec61alpha translocon in polyglutamine-mediated neurotoxicity in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 100: 11723-8. PMID 14504396 DOI: 10.1073/Pnas.1934748100  0.339
2003 Tonchev AB, Yamashima T, Zhao L, Okano HJ, Okano H. Proliferation of neural and neuronal progenitors after global brain ischemia in young adult macaque monkeys. Molecular and Cellular Neurosciences. 23: 292-301. PMID 12812760 DOI: 10.1016/S1044-7431(03)00058-7  0.394
2003 Ishizuya-Oka A, Shimizu K, Sakakibara S, Okano H, Ueda S. Thyroid hormone-upregulated expression of Musashi-1 is specific for progenitor cells of the adult epithelium during amphibian gastrointestinal remodeling. Journal of Cell Science. 116: 3157-64. PMID 12799417 DOI: 10.1242/Jcs.00616  0.394
2003 Sasaki T, Kitagawa K, Sugiura S, Omura-Matsuoka E, Tanaka S, Yagita Y, Okano H, Matsumoto M, Hori M. Implication of cyclooxygenase-2 on enhanced proliferation of neural progenitor cells in the adult mouse hippocampus after ischemia. Journal of Neuroscience Research. 72: 461-71. PMID 12704808 DOI: 10.1002/Jnr.10595  0.393
2003 Yuasa Y, Okabe M, Yoshikawa S, Tabuchi K, Xiong WC, Hiromi Y, Okano H. Drosophila homeodomain protein REPO controls glial differentiation by cooperating with ETS and BTB transcription factors. Development (Cambridge, England). 130: 2419-28. PMID 12702656 DOI: 10.1242/Dev.00468  0.723
2003 Nakamura Y, Yamamoto M, Oda E, Yamamoto A, Kanemura Y, Hara M, Suzuki A, Yamasaki M, Okano H. Expression of tubulin beta II in neural stem/progenitor cells and radial fibers during human fetal brain development. Laboratory Investigation; a Journal of Technical Methods and Pathology. 83: 479-89. PMID 12695551 DOI: 10.1097/01.Lab.0000063930.75913.B3  0.358
2003 Tonchev AB, Yamashima T, Zhao L, Okano H. Differential proliferative response in the postischemic hippocampus, temporal cortex, and olfactory bulb of young adult macaque monkeys. Glia. 42: 209-24. PMID 12673828 DOI: 10.1002/Glia.10209  0.389
2003 Kuo HC, Pau KY, Yeoman RR, Mitalipov SM, Okano H, Wolf DP. Differentiation of monkey embryonic stem cells into neural lineages. Biology of Reproduction. 68: 1727-35. PMID 12606331 DOI: 10.1095/Biolreprod.102.012195  0.418
2003 Kayahara T, Sawada M, Takaishi S, Fukui H, Seno H, Fukuzawa H, Suzuki K, Hiai H, Kageyama R, Okano H, Chiba T. Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine. Febs Letters. 535: 131-5. PMID 12560091 DOI: 10.1016/S0014-5793(02)03896-6  0.389
2003 Potten CS, Booth C, Tudor GL, Booth D, Brady G, Hurley P, Ashton G, Clarke R, Sakakibara S, Okano H. Identification of a putative intestinal stem cell and early lineage marker; musashi-1. Differentiation; Research in Biological Diversity. 71: 28-41. PMID 12558601 DOI: 10.1046/J.1432-0436.2003.700603.X  0.37
2002 Hirota Y, Sawamoto K, Okano H. tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila. Mechanisms of Development. 119: S279-83. PMID 14516698 DOI: 10.1016/S0925-4773(03)00129-1  0.686
2002 Hirota Y, Sawamoto K, Okano H. tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila. Gene Expression Patterns : Gep. 2: 323-7. PMID 12617821 DOI: 10.1016/S0925-4773(02)00387-8  0.686
2002 Sakakibara S, Nakamura Y, Yoshida T, Shibata S, Koike M, Takano H, Ueda S, Uchiyama Y, Noda T, Okano H. RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation. Proceedings of the National Academy of Sciences of the United States of America. 99: 15194-9. PMID 12407178 DOI: 10.1073/Pnas.232087499  0.398
2002 Okano H, Yoshizaki T, Shimazaki T, Sawamoto K. Isolation and transplantation of dopaminergic neurons and neural stem cells. Parkinsonism & Related Disorders. 9: 23-8. PMID 12217619 DOI: 10.1016/S1353-8020(02)00041-X  0.69
2002 Ogawa Y, Sawamoto K, Miyata T, Miyao S, Watanabe M, Nakamura M, Bregman BS, Koike M, Uchiyama Y, Toyama Y, Okano H. Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats. Journal of Neuroscience Research. 69: 925-33. PMID 12205685 DOI: 10.1002/Jnr.10341  0.67
2002 Murayama A, Matsuzaki Y, Kawaguchi A, Shimazaki T, Okano H. Flow cytometric analysis of neural stem cells in the developing and adult mouse brain. Journal of Neuroscience Research. 69: 837-47. PMID 12205677 DOI: 10.1002/Jnr.10339  0.376
2002 Yagita Y, Kitagawa K, Sasaki T, Miyata T, Okano H, Hori M, Matsumoto M. Differential expression of Musashi1 and nestin in the adult rat hippocampus after ischemia. Journal of Neuroscience Research. 69: 750-6. PMID 12205668 DOI: 10.1002/Jnr.10342  0.389
2002 Kuranaga E, Kanuka H, Igaki T, Sawamoto K, Ichijo H, Okano H, Miura M. Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila. Nature Cell Biology. 4: 705-10. PMID 12198495 DOI: 10.1038/Ncb842  0.691
2002 Cuadrado A, García-Fernández LF, Imai T, Okano H, Muñoz A. Regulation of tau RNA maturation by thyroid hormone is mediated by the neural RNA-binding protein musashi-1. Molecular and Cellular Neurosciences. 20: 198-210. PMID 12093154 DOI: 10.1006/Mcne.2002.1131  0.318
2002 Okano H, Imai T, Okabe M. Musashi: a translational regulator of cell fate. Journal of Cell Science. 115: 1355-9. PMID 11896183  0.567
2002 Takasawa K, Kitagawa K, Yagita Y, Sasaki T, Tanaka S, Matsushita K, Ohstuki T, Miyata T, Okano H, Hori M, Matsumoto M. Increased proliferation of neural progenitor cells but reduced survival of newborn cells in the contralateral hippocampus after focal cerebral ischemia in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 299-307. PMID 11891435 DOI: 10.1097/00004647-200203000-00007  0.393
2002 Matsuno K, Ito M, Hori K, Miyashita F, Suzuki S, Kishi N, Artavanis-Tsakonas S, Okano H. Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling. Development (Cambridge, England). 129: 1049-59. PMID 11861487  0.78
2002 Uchida M, Hanai S, Uematsu N, Sawamoto K, Okano H, Miwa M, Uchida K. Overexpression of poly(ADP-ribose) polymerase disrupts organization of cytoskeletal F-actin and tissue polarity in Drosophila. The Journal of Biological Chemistry. 277: 6696-702. PMID 11744702 DOI: 10.1074/Jbc.M109826200  0.71
2002 Toda M, Okano H. Neural stem cell and regeneration of central nervous system Ensho Saisei. 22: 469-473. DOI: 10.2492/Jsir.22.469  0.402
2001 Kohyama J, Abe H, Shimazaki T, Koizumi A, Nakashima K, Gojo S, Taga T, Okano H, Hata J, Umezawa A. Brain from bone: efficient "meta-differentiation" of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent. Differentiation; Research in Biological Diversity. 68: 235-44. PMID 11776476 DOI: 10.1046/J.1432-0436.2001.680411.X  0.414
2001 Yamamoto N, Yamamoto S, Inagaki F, Kawaichi M, Fukamizu A, Kishi N, Matsuno K, Nakamura K, Weinmaster G, Okano H, Nakafuku M. Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor. The Journal of Biological Chemistry. 276: 45031-40. PMID 11564735 DOI: 10.1074/Jbc.M105245200  0.655
2001 Keyoung HM, Roy NS, Benraiss A, Louissaint A, Suzuki A, Hashimoto M, Rashbaum WK, Okano H, Goldman SA. High-yield selection and extraction of two promoter-defined phenotypes of neural stem cells from the fetal human brain. Nature Biotechnology. 19: 843-50. PMID 11533643 DOI: 10.1038/Nbt0901-843  0.4
2001 Sawamoto K, Yamamoto A, Kawaguchi A, Yamaguchi M, Mori K, Goldman SA, Okano H. Direct isolation of committed neuronal progenitor cells from transgenic mice coexpressing spectrally distinct fluorescent proteins regulated by stage-specific neural promoters. Journal of Neuroscience Research. 65: 220-7. PMID 11494356 DOI: 10.1002/Jnr.1145  0.742
2001 Uchida M, Hanai S, Uematsu N, Sawamoto K, Okano H, Miwa M, Uchida K. Genetic and functional analysis of PARP, a DNA strand break-binding enzyme. Mutation Research. 477: 89-96. PMID 11376690 DOI: 10.1016/S0027-5107(01)00110-5  0.695
2001 Imai T, Tokunaga A, Yoshida T, Hashimoto M, Mikoshiba K, Weinmaster G, Nakafuku M, Okano H. The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA. Molecular and Cellular Biology. 21: 3888-900. PMID 11359897 DOI: 10.1128/Mcb.21.12.3888-3900.2001  0.328
2001 Sawamoto K, Nakao N, Kakishita K, Ogawa Y, Toyama Y, Yamamoto A, Yamaguchi M, Mori K, Goldman SA, Itakura T, Okano H. Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3895-903. PMID 11356877  0.71
2001 Sawamoto K, Nakao N, Kobayashi K, Matsushita N, Takahashi H, Kakishita K, Yamamoto A, Yoshizaki T, Terashima T, Murakami F, Itakura T, Okano H. Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 98: 6423-8. PMID 11353855 DOI: 10.1073/Pnas.111152398  0.706
2001 Okabe M, Imai T, Kurusu M, Hiromi Y, Okano H. Translational repression determines a neuronal potential in Drosophila asymmetric cell division. Nature. 411: 94-8. PMID 11333984 DOI: 10.1038/35075094  0.645
2001 Toda M, Iizuka Y, Yu W, Imai T, Ikeda E, Yoshida K, Kawase T, Kawakami Y, Okano H, Uyemura K. Expression of the neural RNA-binding protein Musashi1 in human gliomas. Glia. 34: 1-7. PMID 11284014 DOI: 10.1002/Glia.1034  0.375
2001 Kishi N, Tang Z, Maeda Y, Hirai A, Mo R, Ito M, Suzuki S, Nakao K, Kinoshita T, Kadesch T, Hui C, Artavanis-Tsakonas S, Okano H, Matsuno K. Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 19: 21-35. PMID 11226752 DOI: 10.1016/S0736-5748(00)00071-X  0.762
2001 Kawaguchi A, Miyata T, Sawamoto K, Takashita N, Murayama A, Akamatsu W, Ogawa M, Okabe M, Tano Y, Goldman SA, Okano H. Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells. Molecular and Cellular Neurosciences. 17: 259-73. PMID 11178865 DOI: 10.1006/Mcne.2000.0925  0.774
2001 Sawamoto K, Nakao N, Kakishita K, Ogawa Y, Toyama Y, Yamamoto A, Yamaguchi M, Mori K, Goldman SA, Itakura T, Okano H. Generation of Dopaminergic Neurons in the Adult Brain from Mesencephalic Precursor Cells Labeled with a nestin-GFP Transgene The Journal of Neuroscience. 21: 3895-3903. DOI: 10.1523/Jneurosci.21-11-03895.2001  0.732
2000 Kawashima T, Murakami AR, Ogasawara M, Tanaka KJ, Isoda R, Sasakura Y, Nishikata T, Okano H, Makabe KW. Expression patterns of musashi homologs of the ascidians, Halocynthia roretzi and Ciona intestinalis Development Genes and Evolution. 210: 162-165. PMID 11180818 DOI: 10.1007/S004270050024  0.306
2000 Roy NS, Wang S, Jiang L, Kang J, Benraiss A, Harrison-Restelli C, Fraser RA, Couldwell WT, Kawaguchi A, Okano H, Nedergaard M, Goldman SA. In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus. Nature Medicine. 6: 271-7. PMID 10700228 DOI: 10.1038/73119  0.385
2000 Jin MH, Sawamoto K, Ito M, Okano H. The interaction between the Drosophila secreted protein argos and the epidermal growth factor receptor inhibits dimerization of the receptor and binding of secreted spitz to the receptor. Molecular and Cellular Biology. 20: 2098-107. PMID 10688656 DOI: 10.1128/Mcb.20.6.2098-2107.2000  0.665
2000 Roy NS, Benraiss A, Wang S, Fraser RA, Goodman R, Couldwell WT, Nedergaard M, Kawaguchi A, Okano H, Goldman SA. Promoter-targeted selection and isolation of neural progenitor cells from the adult human ventricular zone. Journal of Neuroscience Research. 59: 321-31. PMID 10679767 DOI: 10.1002/(Sici)1097-4547(20000201)59:3<321::Aid-Jnr5>3.0.Co;2-9  0.414
2000 Tabuchi K, Sawamoto K, Suzuki E, Ozaki K, Sone M, Hama C, Tanifuji-Morimoto T, Yuasa Y, Yoshihara Y, Nose A, Okano H. GAL4/UAS-WGA system as a powerful tool for tracing Drosophila transsynaptic neural pathways. Journal of Neuroscience Research. 59: 94-9. PMID 10658189 DOI: 10.1002/(Sici)1097-4547(20000101)59:1<94::Aid-Jnr11>3.0.Co;2-Q  0.713
2000 Kaneko Y, Sakakibara S, Imai T, Suzuki A, Nakamura Y, Sawamoto K, Ogawa Y, Toyama Y, Miyata T, Okano H. Musashi1: an evolutionally conserved marker for CNS progenitor cells including neural stem cells. Developmental Neuroscience. 22: 139-53. PMID 10657706 DOI: 10.1159/000017435  0.738
2000 Igaki T, Kanuka H, Inohara N, Sawamoto K, Núñez G, Okano H, Miura M. Drob-1, a Drosophila member of the Bcl-2/CED-9 family that promotes cell death. Proceedings of the National Academy of Sciences of the United States of America. 97: 662-7. PMID 10639136 DOI: 10.1073/Pnas.97.2.662  0.679
2000 Nakamura Y, Sakakibara S, Miyata T, Ogawa M, Shimazaki T, Weiss S, Kageyama R, Okano H. The bHLH GeneHes1as a Repressor of the Neuronal Commitment of CNS Stem Cells The Journal of Neuroscience. 20: 283-293. DOI: 10.1523/Jneurosci.20-01-00283.2000  0.39
1999 Kanuka H, Sawamoto K, Inohara N, Matsuno K, Okano H, Miura M. Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator. Molecular Cell. 4: 757-69. PMID 10619023 DOI: 10.1016/S1097-2765(00)80386-X  0.761
1999 Fujimoto J, Sawamoto K, Okabe M, Takagi Y, Tezuka T, Yoshikawa S, Ryo H, Okano H, Yamamoto T. Cloning and characterization of Dfak56, a homolog of focal adhesion kinase, in Drosophila melanogaster. The Journal of Biological Chemistry. 274: 29196-201. PMID 10506176 DOI: 10.1074/Jbc.274.41.29196  0.74
1999 Hirota Y, Okabe M, Imai T, Kurusu M, Yamamoto A, Miyao S, Nakamura M, Sawamoto K, Okano H. Musashi and seven in absentia downregulate Tramtrack through distinct mechanisms in Drosophila eye development. Mechanisms of Development. 87: 93-101. PMID 10495274 DOI: 10.1016/S0925-4773(99)00143-4  0.771
1999 Akamatsu W, Okano HJ, Osumi N, Inoue T, Nakamura S, Sakakibara S, Miura M, Matsuo N, Darnell RB, Okano H. Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems. Proceedings of the National Academy of Sciences of the United States of America. 96: 9885-90. PMID 10449789 DOI: 10.1073/Pnas.96.17.9885  0.417
1999 Sawamoto K, Winge P, Koyama S, Hirota Y, Yamada C, Miyao S, Yoshikawa S, Jin MH, Kikuchi A, Okano H. The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH(2)-terminal kinase pathway. The Journal of Cell Biology. 146: 361-72. PMID 10427090 DOI: 10.1083/Jcb.146.2.361  0.702
1999 Rocheleau CE, Yasuda J, Shin TH, Lin R, Sawa H, Okano H, Priess JR, Davis RJ, Mello CC. WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans. Cell. 97: 717-26. PMID 10380924 DOI: 10.1016/S0092-8674(00)80784-9  0.336
1999 Sawamoto K, Yamada C, Kishida S, Hirota Y, Taguchi A, Kikuchi A, Okano H. Ectopic expression of constitutively activated Ral GTPase inhibits cell shape changes during Drosophila eye development. Oncogene. 18: 1967-74. PMID 10208418 DOI: 10.1038/Sj.Onc.1202522  0.706
1999 Yoshihara Y, Mizuno T, Nakahira M, Kawasaki M, Watanabe Y, Kagamiyama H, Jishage Ki, Ueda O, Suzuki H, Tabuchi K, Sawamoto K, Okano H, Noda T, Mori K. A genetic approach to visualization neurotechnique of multisynaptic neural pathways using plant lectin transgene Neuron. 22: 33-41. PMID 10027287 DOI: 10.1016/S0896-6273(00)80676-5  0.693
1999 Kanuka H, Hisahara S, Sawamoto K, Shoji SI, Okano H, Miura M. Proapoptotic activity of Caenorhabditis elegans CED-4 protein in Drosophila: Implicated mechanisms for caspase activation Proceedings of the National Academy of Sciences of the United States of America. 96: 145-150. PMID 9874786 DOI: 10.1073/Pnas.96.1.145  0.684
1998 Sawamoto K, Taguchi A, Hirota Y, Yamada C, Jin MH, Okano H. Argos induces programmed cell death in the developing Drosophila eye by inhibition of the Ras pathway Cell Death and Differentiation. 5: 262-270. PMID 10200472 DOI: 10.1038/Sj.Cdd.4400342  0.694
1998 Tabuchi K, Yoshikawa S, Yuasa Y, Sawamoto K, Okano H. A novel Drosophila paired-like homeobox gene related to Caenorhabditis elegans unc-4 is expressed in subsets of postmitotic neurons and epidermal cells Neuroscience Letters. 257: 49-52. PMID 9857963 DOI: 10.1016/S0304-3940(98)00799-X  0.719
1998 Saito T, Sawamoto K, Okano H, Anderson DJ, Mikoshiba K. Mammalian BarH homologue is a potential regulator of neural bHLH genes Developmental Biology. 199: 216-225. PMID 9698441 DOI: 10.1006/Dbio.1998.8889  0.728
1998 Pincus DW, Keyoung HM, Harrison-Restelli C, Goodman RR, Fraser RA, Edgar M, Sakakibara S, Okano H, Nedergaard M, Goldman SA. Fibroblast growth factor-2/brain-derived neurotrophic factor-associated maturation of new neurons generated from adult human subependymal cells. Annals of Neurology. 43: 576-85. PMID 9585351 DOI: 10.1002/Ana.410430505  0.362
1998 Okano H, Sawamoto K, Kanuka H, Taguchi A, Hisahara S, Miura M. Molecular genetic studies of Drosophila programmed cell death Neuroscience Research. 31: S52. DOI: 10.1016/S0168-0102(98)81802-6  0.654
1997 Okano H, Okabe M, Taguchi A, Sawamoto K. Evolutionarily conserved mechanisms regulating neural development: lessons from the development of Drosophila peripheral nervous systems. Human Cell. 10: 139-50. PMID 9436033  0.746
1997 Okabe M, Sawamoto K, Imai T, Sakakibara S, Yoshikawa S, Okano H. Intrinsic and extrinsic determinants regulating cell fate decision in developing nervous system. Developmental Neuroscience. 19: 9-16. PMID 9078426 DOI: 10.1159/000111178  0.774
1997 Okabe M, Okano H. Two-step induction of chordotonal organ precursors in Drosophila embryogenesis. Development (Cambridge, England). 124: 1045-53. PMID 9056779  0.551
1996 Sawamoto K, Okano H. Cell-cell interactions during neural development: Multiple types of lateral inhibitions involved in Drosophila eye development Neuroscience Research. 26: 205-214. PMID 9121731 DOI: 10.1016/S0168-0102(96)01110-8  0.716
1996 Sawamoto K, Okabe M, Tanimura T, Hayashi S, Mikoshiba K, Okano H. argos Is required for projection of photoreceptor axons during optic lobe development in Drosophila. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 205: 162-71. PMID 8834476 DOI: 10.1002/(Sici)1097-0177(199602)205:2<162::Aid-Aja7>3.0.Co;2-G  0.74
1996 Sawamoto K, Okabe M, Tanimura T, Mikoshiba K, Nishida Y, Okano H. The Drosophila secreted protein Argos regulates signal transduction in the Ras/MAPK pathway. Developmental Biology. 178: 13-22. PMID 8812105 DOI: 10.1006/Dbio.1996.0194  0.74
1996 Sakakibara S, Imai T, Hamaguchi K, Okabe M, Aruga J, Nakajima K, Yasutomi D, Nagata T, Kurihara Y, Uesugi S, Miyata T, Ogawa M, Mikoshiba K, Okano H. Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell. Developmental Biology. 176: 230-42. PMID 8660864 DOI: 10.1006/Dbio.1996.0130  0.605
1996 Okabe M, Sawamoto K, Okano H. The function of the Drosophila argos gene product in the development of embryonic chordotonal organs. Developmental Biology. 175: 37-49. PMID 8608867 DOI: 10.1006/Dbio.1996.0093  0.725
1996 Matsumoto M, Nakagawa T, Inoue T, Nagata E, Tanaka K, Takano H, Minowa O, Kuno J, Sakakibara S, Yamada M, Yoneshima H, Miyawaki A, Fukuuchi Y, Furuichi T, Okano H, et al. Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor. Nature. 379: 168-71. PMID 8538767 DOI: 10.1038/379168A0  0.318
1996 Okano H, Sawamoto K, Okabe M, Imai T, Sakakibara S, Yoshikawa S. S1-1 Role of intrinsic and extrinsic determinants in cell fate decision during neural development Neuroscience Research. 25: S2. DOI: 10.1016/0168-0102(96)88559-2  0.739
1995 Mikoshiba K, Okano H, Miyawaki A, Furuichi T, Ikenaka K. Molecular genetic analyses of myelin deficiency and cerebellar ataxia. Progress in Brain Research. 105: 23-41. PMID 7568881 DOI: 10.1016/S0079-6123(08)63281-1  0.35
1994 Nakamura M, Okano H, Blendy JA, Montell C. Musashi, a neural RNA-binding protein required for Drosophila adult external sensory organ development. Neuron. 13: 67-81. PMID 8043282 DOI: 10.1016/0896-6273(94)90460-X  0.69
1994 Sawamoto K, Okano H, Kobayakawa Y, Hayashi S, Mikoshiba K, Tanimura T. The function of argos in regulating cell fate decisions during Drosophila eye and wing vein development Developmental Biology. 164: 267-276. PMID 8026629 DOI: 10.1006/Dbio.1994.1197  0.723
1994 Okano H, Yoshikawa S, Suzuki A, Ueno N, Kaizu M, Okabe M, Takahashi T, Matsumoto M, Sawamoto K, Mikoshiba K. Cloning of a Drosophila melanogaster homologue of the mouse type-I bone morphogenetic proteins-2/-4 receptor: a potential decapentaplegic receptor. Gene. 148: 203-9. PMID 7958946  0.479
1994 Xiong WC, Okano H, Patel NH, Blendy JA, Montell C. repo encodes a glial-specific homeo domain protein required in the Drosophila nervous system. Genes & Development. 8: 981-94. PMID 7926782 DOI: 10.1101/Gad.8.8.981  0.707
1994 Kagawa T, Ikenaka K, Inoue Y, Kuriyama S, Tsujii T, Nakao J, Nakajima K, Aruga J, Okano H, Mikoshiba K. Glial cell degeneration and hypomyelination caused by overexpression of myelin proteolipid protein gene. Neuron. 13: 427-42. PMID 7520255 DOI: 10.1016/0896-6273(94)90358-1  0.339
1994 Sawamoto K, Okabe M, Yoshikawa S, Mikoshiba K, Okano H. The role of strawberry in optic lobe development and projection of photoreceptor axons Neuroscience Research Supplements. 19: S94. DOI: 10.1016/0921-8696(94)92527-5  0.695
1994 Okabe M, Okano H, Sawamoto K, Yoshikawa S, Mikoshiba K. The molecular genetic dissection of strawberry gene function in drosophila embryonic development Neuroscience Research Supplements. 19: S94. DOI: 10.1016/0921-8696(94)92526-7  0.722
1993 Okano H, Yoshikawa S, Sawamoto K, Sakakibara S, Mikoshiba K. S4-1 Analyses of neural development using drosophila melanogaster Neuroscience Research Supplements. 18: S8. DOI: 10.1016/S0921-8696(05)80693-0  0.662
1992 Okano H, Hayashi S, Tanimura T, Sawamoto K, Yoshikawa S, Watanabe J, Iwasaki M, Hirose S, Mikoshiba K, Montell C. Regulation of Drosophila neural development by a putative secreted protein. Differentiation; Research in Biological Diversity. 52: 1-11. PMID 1286772 DOI: 10.1111/J.1432-0436.1992.Tb00494.X  0.771
1992 Okano H, Sakakibara S, Nakamura M, Blendy J, Montell C, Mikoshiba K. Spike, a novel drosophila phototransduction mutant identified by P-element insertion mutagenesis Neuroscience Research Supplements. 17: 140. DOI: 10.1016/0921-8696(92)90916-O  0.614
1992 Okano H, Sawamoto K, Yoshikawa S, Hayashi S, Tanimura T, Watanabe J, Hirose S, Iwasaki M, Montell C, Mikoshiba K. The strawberry gene encodes a novel secreted protein with an EGF motif regulating a neuronal cell differentiation and axonal guidance Neuroscience Research Supplements. 17: 140. DOI: 10.1016/0921-8696(92)90915-N  0.771
1991 Turnley AM, Morahan G, Okano H, Bernard O, Mikoshiba K, Allison J, Bartlett PF, Miller JF. Dysmyelination in transgenic mice resulting from expression of class I histocompatibility molecules in oligodendrocytes. Nature. 353: 566-9. PMID 1717849 DOI: 10.1038/353566A0  0.304
1987 Mikoshiba K, Okano H, Inoue Y, Fujishiro M, Takamatsu K, Lachapelle F, Baumann N, Tsukada Y. Immunohistochemical, biochemical and electron microscopic analysis of myelin formation in the central nervous system of myelin deficient (mld) mutant mice. Brain Research. 432: 111-21. PMID 2443219 DOI: 10.1016/0165-3806(87)90013-7  0.449
1987 Okano H, Miura M, Moriguchi A, Ikenaka K, Tsukada Y, Mikoshiba K. Inefficient transcription of the myelin basic protein gene possibly causes hypomyelination in myelin-deficient mutant mice. Journal of Neurochemistry. 48: 470-6. PMID 2432182 DOI: 10.1111/J.1471-4159.1987.Tb04116.X  0.486
1986 Mikoshiba K, Yokoyama M, Terashima H, Nishimura Y, Inoue Y, Okano H, Takamatsu K, Nomura T, Tsukada Y. Studies on the development and growth of the mammalian nervous system by aggregation chimeras: analysis of corticohistogenesis in the cerebrum by reeler mutant mice. Progress in Clinical and Biological Research. 217: 137-40. PMID 3749172  0.375
1985 Mikoshiba K, Okano H, Tsukada Y. P400 protein characteristic to Purkinje cells and related proteins in cerebella from neuropathological mutant mice: autoradiographic study by 14C-leucine and phosphorylation. Developmental Neuroscience. 7: 179-87. PMID 4076002 DOI: 10.1159/000112286  0.469
1985 Mikoshiba K, Fujishiro M, Kohsaka S, Okano H, Takamatsu K, Tsukada Y. Disorders in myelination in the twitcher mutant: immunohistochemical and biochemical studies. Neurochemical Research. 10: 1129-41. PMID 2414681 DOI: 10.1007/Bf00965887  0.467
1985 Mikoshiba K, Okano H, Fujishiro M, Tsukada Y. Immunohistochemical studies and 2-dimensional gel electrophoretic analysis on the cerebellum from the staggerer mutant mouse Neuroscience Research. 3: S33. DOI: 10.1016/S0921-8696(85)80063-3  0.449
1985 Mikoshiba K, Okano H, Fujishiro M, Tsukada Y. Immunohistochemical studies and 2-dimensional gel electrophoretic analysis on the cerebellum from the staggerer mutant mouse Neuroscience Research Supplements. 1: S33. DOI: 10.1016/S0921-8696(85)80063-3  0.373
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