Stephen V. Desiderio - Publications

Molecular Biology and Genetics Johns Hopkins University School of Medicine, Baltimore, MD, United States 
Development of Immune System

83 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Lu C, Ward A, Bettridge J, Liu Y, Desiderio S. An autoregulatory mechanism imposes allosteric control on the V(D)J recombinase by histone H3 methylation. Cell Reports. 10: 29-38. PMID 25543141 DOI: 10.1016/j.celrep.2014.12.001  0.64
2013 Halper-Stromberg E, Steranka J, Giraldo-Castillo N, Fuller T, Desiderio S, Burns KH. Fine mapping of V(D)J recombinase mediated rearrangements in human lymphoid malignancies Bmc Genomics. 14. PMID 23957733 DOI: 10.1186/1471-2164-14-565  0.64
2013 Rybanska-Spaeder I, Reynolds TL, Chou J, Prakash M, Jefferson T, Huso DL, Desiderio S, Franco S. 53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation. Molecular Cancer Research : McR. 11: 1223-34. PMID 23858098 DOI: 10.1158/1541-7786.MCR-13-0252-T  0.64
2013 Lee J, Baldwin WM, Lee CY, Desiderio S. Stat3β mitigates development of atherosclerosis in apolipoprotein E-deficient mice Journal of Molecular Medicine. 91: 965-976. PMID 23619910 DOI: 10.1007/s00109-013-1013-5  0.64
2013 Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M, Clark HM, Hu S, Hwang W, Jeong JS, Wu G, Lin J, Gao X, ... ... Desiderio S, et al. Construction of human activity-based phosphorylation networks. Molecular Systems Biology. 9: 655. PMID 23549483 DOI: 10.1038/msb.2013.12  0.64
2013 Thapa P, Das J, McWilliams D, Shapiro M, Sundsbak R, Nelson-Holte M, Tangen S, Anderson J, Desiderio S, Hiebert S, Sant'angelo DB, Shapiro VS. The transcriptional repressor NKAP is required for the development of iNKT cells. Nature Communications. 4: 1582. PMID 23481390 DOI: 10.1038/ncomms2580  0.64
2012 Cooper CL, Hardy RR, Reth M, Desiderio S. Non-cell-autonomous hedgehog signaling promotes murine B lymphopoiesis from hematopoietic progenitors. Blood. 119: 5438-48. PMID 22517907 DOI: 10.1182/blood-2011-12-397976  0.64
2012 Greenblatt S, Li L, Slape C, Nguyen B, Novak R, Duffield A, Huso D, Desiderio S, Borowitz MJ, Aplan P, Small D. Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model. Blood. 119: 2883-94. PMID 22323452 DOI: 10.1182/blood-2011-10-382283  0.64
2011 Zhang L, Reynolds TL, Shan X, Desiderio S. Coupling of V(D)J recombination to the cell cycle suppresses genomic instability and lymphoid tumorigenesis. Immunity. 34: 163-74. PMID 21349429 DOI: 10.1016/j.immuni.2011.02.003  0.64
2011 Li L, Zhang L, Fan J, Greenberg K, Desiderio S, Rassool FV, Small D. Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice. Blood. 117: 3131-9. PMID 21228325 DOI: 10.1182/blood-2010-05-286070  0.64
2010 Desiderio S. Temporal and spatial regulatory functions of the V(D)J recombinase Seminars in Immunology. 22: 362-369. PMID 21036059 DOI: 10.1016/j.smim.2010.09.001  0.64
2010 Kandasamy K, Mohan SS, Raju R, Keerthikumar S, Kumar GS, Venugopal AK, Telikicherla D, Navarro JD, Mathivanan S, Pecquet C, Gollapudi SK, Tattikota SG, Mohan S, Padhukasahasram H, Subbannayya Y, ... ... Desiderio S, et al. NetPath: a public resource of curated signal transduction pathways. Genome Biology. 11: R3. PMID 20067622 DOI: 10.1186/gb-2010-11-1-r3  0.64
2009 Liu Y, Zhang L, Desiderio S. Temporal and spatial regulation of V(D)J recombination: Interactions of extrinsic factors with the RAG complex Advances in Experimental Medicine and Biology. 650: 157-165. PMID 19731809 DOI: 10.1007/978-1-4419-0296-2_13  0.64
2009 Zachos NC, van Rossum DB, Li X, Caraveo G, Sarker R, Cha B, Mohan S, Desiderio S, Patterson RL, Donowitz M. Phospholipase C-gamma binds directly to the Na+/H+ exchanger 3 and is required for calcium regulation of exchange activity. The Journal of Biological Chemistry. 284: 19437-44. PMID 19473983 DOI: 10.1074/jbc.M109.006098  0.64
2008 Desiderio S. Along Came a Spider: AID Escapes a MicroRNA Web Immunity. 28: 596-598. PMID 18482561 DOI: 10.1016/j.immuni.2008.04.012  0.64
2008 Marton HA, Desiderio S. The Paf1 complex promotes displacement of histones upon rapid induction of transcription by RNA polymerase II Bmc Molecular Biology. 9. PMID 18194564 DOI: 10.1186/1471-2199-9-4  0.64
2007 Liu Y, Subrahmanyam R, Chakraborty T, Sen R, Desiderio S. A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement. Immunity. 27: 561-71. PMID 17936034 DOI: 10.1016/j.immuni.2007.09.005  0.64
2007 Youn MY, Yoo HS, Kim MJ, Hwang SY, Choi Y, Desiderio SV, Yoo JY. hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions. The Journal of Biological Chemistry. 282: 34727-34. PMID 17911113 DOI: 10.1074/jbc.M705411200  0.64
2006 Caraveo G, van Rossum DB, Patterson RL, Snyder SH, Desiderio S. Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry. Science (New York, N.Y.). 314: 122-5. PMID 17023658 DOI: 10.1126/science.1127815  0.64
2005 Jiang H, Chang FC, Ross AE, Lee J, Nakayama K, Desiderio S. Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle Molecular Cell. 18: 699-709. PMID 15949444 DOI: 10.1016/j.molcel.2005.05.011  0.64
2005 Jackson TA, Taylor HE, Sharma D, Desiderio S, Danoff SK. Vascular endothelial growth factor receptor-2: counter-regulation by the transcription factors, TFII-I and TFII-IRD1. The Journal of Biological Chemistry. 280: 29856-63. PMID 15941713 DOI: 10.1074/jbc.M500335200  0.64
2004 Danoff SK, Taylor HE, Blackshaw S, Desiderio S. TFII-I, a candidate gene for Williams syndrome cognitive profile: parallels between regional expression in mouse brain and human phenotype. Neuroscience. 123: 931-8. PMID 14751286 DOI: 10.1016/j.neuroscience.2003.08.038  0.64
2004 Jiang H, Ross AE, Desiderio S. Cycle-dependent Accumulation in Vivo of Transposition-competent Complexes between Recombination Signal Ends and Full-length RAG Proiteins Journal of Biological Chemistry. 279: 8478-8486. PMID 14660558 DOI: 10.1074/jbc.M311219200  0.64
2003 Tretter T, Ross AE, Dordai DI, Desiderio S. Mimicry of Pre-B Cell Receptor Signaling by Activation of the Tyrosine Kinase Blk Journal of Experimental Medicine. 198: 1863-1873. PMID 14662906 DOI: 10.1084/jem.20030729  0.64
2003 Ross AE, Vuica M, Desiderio S. Overlapping signals for protein degradation and nuclear localization define a role for intrinsic RAG-2 nuclear uptake in dividing cells Molecular and Cellular Biology. 23: 5308-5319. PMID 12861017 DOI: 10.1128/MCB.23.15.5308-5319.2003  0.64
2003 Desiderio S, Yoo JY. A genome-wide analysis of the acute-phase response and its regulation by Stat3β Annals of the New York Academy of Sciences. 987: 280-284. PMID 12727653  0.64
2003 Yoo JY, Desiderio S. Innate and acquired immunity intersect in a global view of the acute-phase response Proceedings of the National Academy of Sciences of the United States of America. 100: 1157-1162. PMID 12540827 DOI: 10.1073/pnas.0336385100  0.64
2002 Casteel DE, Zhuang S, Gudi T, Tang J, Vuica M, Desiderio S, Pilz RB. cGMP-dependent protein kinase Iβ physically and functionally interacts with the transcriptional regulator TFII-I Journal of Biological Chemistry. 277: 32003-32014. PMID 12082086 DOI: 10.1074/jbc.M112332200  0.64
2002 Yoo JY, Huso DL, Nathans D, Desiderio S. Specific ablation of Stat3beta distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock. Cell. 108: 331-44. PMID 11853668 DOI: 10.1016/S0092-8674(02)00636-0  0.64
2001 Egloff AM, Desiderio S. Identification of Phosphorylation Sites for Bruton's Tyrosine Kinase within the Transcriptional Regulator BAP/TFII-I Journal of Biological Chemistry. 276: 27806-27815. PMID 11373296 DOI: 10.1074/jbc.M103692200  0.64
2001 Li W, Chang FC, Desiderio S. RAG-1 mutations associated with B-Cell-negative SCID dissociate the nicking and transesterification steps of V(D)J recombination Molecular and Cellular Biology. 21: 3935-3946. PMID 11359901 DOI: 10.1128/MCB.21.12.3935-3946.2001  0.64
2001 Yoo JY, Wang W, Desiderio S, Nathans D. Synergistic activity of STAT3 and c-Jun at a specific array of DNA elements in the alpha 2-macroglobulin promoter. The Journal of Biological Chemistry. 276: 26421-9. PMID 11319221 DOI: 10.1074/jbc.M009935200  0.64
2000 Desiderio S. Somatic evolution of antibody specificity: Setting the clock forward Nature Immunology. 1: 463-464. PMID 11101864  0.64
2000 Texido G, Su IH, Mecklenbräuker I, Saijo K, Malek SN, Desiderio S, Rajewsky K, Tarakhovsky A. The B-cell-specific Src-family kinase Blk is dispensable for B-cell development and activation. Molecular and Cellular Biology. 20: 1227-33. PMID 10648608 DOI: 10.1128/MCB.20.4.1227-1233.2000  0.64
1999 Lee J, Desiderio S. Cyclin A/CDK2 regulates V(D)J recombination by coordinating RAG-2 accumulation and DNA repair Immunity. 11: 771-781. PMID 10626899  0.64
1999 Desiderio S, Lee J. Signaling pathways that control V(D)J recombination Current Topics in Microbiology and Immunology. 245: 31-56. PMID 10533317  0.64
1999 Swanson PC, Desiderio S. RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex Molecular and Cellular Biology. 19: 3674-3683. PMID 10207091  0.64
1998 Swanson PC, Desiderio S. V(D)J recombination signal recognition: Distinct, overlapping DNA- protein contacts in complexes containing RAG1 with and without RAG2 Immunity. 9: 115-125. PMID 9697841 DOI: 10.1016/S1074-7613(00)80593-2  0.64
1998 Malek SN, Dordai DI, Reim J, Dintzis H, Desiderio S. Malignant transformation of early lymphoid progenitors in mice expressing an activated Blk tyrosine kinase Proceedings of the National Academy of Sciences of the United States of America. 95: 7351-7356. PMID 9636152 DOI: 10.1073/pnas.95.13.7351  0.64
1997 Li W, Swanson P, Desiderio S. RAG-1- and RAG-2-dependent assembly of functional complexes with V(D)J recombination substrates in solution Molecular and Cellular Biology. 17: 6932-6939. PMID 9372925  0.64
1997 Desiderio S. Role of Btk in B cell development and signaling Current Opinion in Immunology. 9: 534-540. PMID 9287186 DOI: 10.1016/S0952-7915(97)80107-0  0.64
1997 Vuica M, Desiderio S, Schneck JP. Differential effects of B cell receptor and B cell receptor-FcγRIIB1 engagement on docking of Csk to GTPase-activating protein (GAP)-associated p62 Journal of Experimental Medicine. 186: 259-267. PMID 9221755 DOI: 10.1084/jem.186.2.259  0.64
1997 Zwollo P, Arrieta H, Ede K, Molinder K, Desiderio S, Pollock R. The Pax-5 gene is alternatively spliced during B-cell development Journal of Biological Chemistry. 272: 10160-10168. PMID 9092562 DOI: 10.1074/jbc.272.15.10160  0.64
1997 Yang W, Desiderio S. Bap-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement Proceedings of the National Academy of Sciences of the United States of America. 94: 604-609. PMID 9012831 DOI: 10.1073/pnas.94.2.604  0.64
1996 Li Z, Dordai DI, Lee J, Desiderio S. A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle Immunity. 5: 575-589. PMID 8986717 DOI: 10.1016/S1074-7613(00)80272-1  0.64
1996 Schwarz K, Gauss GH, Ludwig L, Pannicke U, Li Z, Lindner D, Friedrich W, Seger RA, Hansen-Hagge TE, Desiderio S, Lieber MR, Bartram CR. RAG mutations in human B cell-negative SCID. Science (New York, N.Y.). 274: 97-9. PMID 8810255 DOI: 10.1126/science.274.5284.97  0.64
1996 Desiderio S, Lin WC, Li Z. The cell cycle and V(D)J recombination Current Topics in Microbiology and Immunology. 217: 45-59. PMID 8787617  0.64
1996 Malek SN, Yang CH, Earnshaw WC, Kozak CA, Desiderio S. p150TSP, a conserved nuclear phosphoprotein that contains multiple tetratricopeptide repeats and binds specifically to SH2 domains. The Journal of Biological Chemistry. 271: 6952-62. PMID 8636124  0.64
1995 Lin WC, Desiderio S. V(D)J recombination and the cell cycle Immunology Today. 16: 279-289. PMID 7662097 DOI: 10.1016/0167-5699(95)80182-0  0.64
1995 Yang W, Malek SN, Desiderio S. An SH3-binding site conserved in Bruton's tyrosine kinase and related tyrosine kinases mediates specific protein interactions in vitro and in vivo Journal of Biological Chemistry. 270: 20832-20840. PMID 7657668 DOI: 10.1074/jbc.270.35.20832  0.64
1995 Desiderio S. Lymphopoiesis: Transcription factors controlling B-cell development Current Biology. 5: 605-608. PMID 7552167 DOI: 10.1016/S0960-9822(95)00121-7  0.64
1994 Zwollo P, Desiderio S. Specific recognition of the blk promoter by the B-lymphoid transcription factor B-cell-specific activator protein Journal of Biological Chemistry. 269: 15310-15317. PMID 8195169  0.64
1994 Lin WC, Desiderio S. Cell cycle regulation of V(D)J recombination-activating protein RAG-2 Proceedings of the National Academy of Sciences of the United States of America. 91: 2733-2737. PMID 8146183  0.64
1994 Desiderio S. The B cell antigen receptor in B-cell development Current Opinion in Immunology. 6: 248-256. PMID 8011209 DOI: 10.1016/0952-7915(94)90098-1  0.64
1994 Desiderio S, Siliciano JD. The Itk/Btk/Tec family of protein-tyrosine kinases Chemical Immunology. 59: 191-210. PMID 7945928  0.64
1994 Janis EM, Siliciano JD, Isaac DD, Griffin CA, Hawkins AL, Kozak CA, Desiderio S. Mapping of the gene for the tyrosine kinase Itk to a region of conserved synteny between mouse chromosome 11 and human chromosome 5q. Genomics. 23: 269-71. PMID 7829087 DOI: 10.1006/geno.1994.1492  0.64
1994 Malek SN, Desiderio S. A Cyclin-dependent Kinase Homologue, p130PITSLRE, Is a Phosphotyrosine-independent SH2 Ligand Journal of Biological Chemistry. 269: 33009-33020. PMID 7528743  0.64
1994 Amzel LM, Garcia KC, Desiderio S. Do antiidiotypic antibodies mimic antigen? Research in Immunology. 145: 53-55. PMID 7516565 DOI: 10.1016/S0923-2494(94)80044-8  0.64
1993 Lin WC, Desiderio S. Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation Science. 260: 953-959. PMID 8493533  0.64
1993 Klages S, Adam D, Eiseman E, Fargnoli J, Dymecki SM, Desiderio SV, Bolen JB. Molecular cloning and analysis of cDNA encoding the murine c-yes tyrosine protein kinase. Oncogene. 8: 713-9. PMID 8437854  0.64
1993 Oltz EM, Alt FW, Lin WC, Chen J, Taccioli G, Desiderio S, Rathbun G. A V(D)J recombinase-inducible B-cell line: role of transcriptional enhancer elements in directing V(D)J recombination. Molecular and Cellular Biology. 13: 6223-30. PMID 8413222  0.64
1993 Wange RL, Malek SN, Desiderio S, Samelson LE. Tandem SH2 domains of ZAP-70 bind to T cell antigen receptor ζ and CD3∈ from activated Jurkat T cells Journal of Biological Chemistry. 268: 19797-19801. PMID 8366117  0.64
1993 Malek SN, Desiderio S. SH2 domains of the protein-tyrosine kinases Blk, Lyn, and Fyn(T) bind distinct sets of phosphoproteins from B lymphocytes Journal of Biological Chemistry. 268: 22557-22565. PMID 8226767  0.64
1993 Desiderio S. Becoming B cells Nature. 361: 202-203. PMID 7678697  0.64
1992 Garcia KC, Desiderio SV, Ronco PM, Verroust PJ, Amzel LM. Recognition of angiotensin II: antibodies at different levels of an idiotypic network are superimposable. Science (New York, N.Y.). 257: 528-31. PMID 1636087  0.64
1992 Dymecki SM, Zwollo P, Zeller K, Kuhajda FP, Desiderio SV. Structure and developmental regulation of the B-lymphoid tyrosine kinase gene blk. The Journal of Biological Chemistry. 267: 4815-23. PMID 1537861  0.64
1992 Desiderio SV. B-cell activation. Current Opinion in Immunology. 4: 252-6. PMID 1418702 DOI: 10.1016/0952-7915(92)90073-N  0.64
1992 Siliciano JD, Morrow TA, Desiderio SV. itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2. Proceedings of the National Academy of Sciences of the United States of America. 89: 11194-8. PMID 1280821  0.64
1991 Kozak CA, Dymecki SM, Niederhuber JE, Desiderio SV. Genetic mapping of the gene for a novel tyrosine kinase, Blk, to mouse chromosome 14. Genomics. 9: 762-4. PMID 2037301 DOI: 10.1016/0888-7543(91)90372-L  0.64
1991 Wilson RB, Kiledjian M, Shen CP, Benezra R, Zwollo P, Dymecki SM, Desiderio SV, Kadesch T. Repression of immunoglobulin enhancers by the helix-loop-helix protein Id: implications for B-lymphoid-cell development. Molecular and Cellular Biology. 11: 6185-91. PMID 1944284  0.64
1991 Alessandrini A, Desiderio SV. Coordination of immunoglobulin DJH transcription and D-to-JH rearrangement by promoter-enhancer approximation. Molecular and Cellular Biology. 11: 2096-107. PMID 1900920  0.64
1990 Dymecki SM, Niederhuber JE, Desiderio SV. Specific expression of a tyrosine kinase gene, blk, in B lymphoid cells. Science (New York, N.Y.). 247: 332-6. PMID 2404338  0.64
1989 Li M, Morzycka-Wroblewska E, Desiderio SV. NBP, a protein that specifically binds an enhancer of immunoglobulin gene rearrangement: purification and characterization. Genes & Development. 3: 1801-13. PMID 2606349  0.64
1988 Morzycka-Wroblewska E, Lee FE, Desiderio SV. Unusual immunoglobulin gene rearrangement leads to replacement of recombinational signal sequences. Science (New York, N.Y.). 242: 261-3. PMID 3140378  0.64
1988 Desiderio SV, Wolff KR. Rearrangement of exogenous immunoglobulin VH and DJH gene segments after retroviral transduction into immature lymphoid cell lines. The Journal of Experimental Medicine. 167: 372-88. PMID 2831291  0.64
1987 Alessandrini A, Pierce JH, Baltimore D, Desiderio SV. Continuing rearrangement of immunoglobulin and T-cell receptor genes in a Ha-ras-transformed lymphoid progenitor cell line. Proceedings of the National Academy of Sciences of the United States of America. 84: 1799-803. PMID 3470759  0.64
1987 Halligan BD, Desiderio SV. Identification of a DNA binding protein that recognizes the nonamer recombinational signal sequence of immunoglobulin genes. Proceedings of the National Academy of Sciences of the United States of America. 84: 7019-23. PMID 3118358  0.64
1984 Desiderio S, Baltimore D. Double-stranded cleavage by cell extracts near recombinational signal sequences of immunoglobulin genes Nature. 308: 860-862. PMID 6325923 DOI: 10.1038/308860a0  0.64
1984 Desiderio SV, Yancopoulos GD, Paskind M, Thomas E, Boss MA, Landau N, Alt FW, Baltimore D. Insertion of N regions into heavy-chain genes is correlated with expression of terminal deoxytransferase in B cells. Nature. 311: 752-5. PMID 6092963 DOI: 10.1038/311752a0  0.64
1984 Yancopoulos GD, Desiderio SV, Paskind M, Kearney JF, Baltimore D, Alt FW. Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines. Nature. 311: 727-33. PMID 6092962 DOI: 10.1038/311727a0  0.64
1981 Desiderio SV, Kelly TJ. Structure of the linkage between adenovirus DNA and the 55,000 molecular weight terminal protein. Journal of Molecular Biology. 145: 319-37. PMID 7265205 DOI: 10.1016/0022-2836(81)90208-4  0.64
1980 Challberg MD, Desiderio SV, Kelly TJ. Adenovirus DNA replication in vitro: characterization of a protein covalently linked to nascent DNA strands. Proceedings of the National Academy of Sciences of the United States of America. 77: 5105-9. PMID 6933548  0.64
1978 Desiderio S, Boyer S. Arber, Smith and Nathans: Nobel laureates in medicine and physiology, 1978 Johns Hopkins Medical Journal. 143: IX-X. PMID 364154  0.64
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