Leonard L. Howell - Publications

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116 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Curry DW, Berro LF, Belkoff AR, Sulima A, Rice KC, Howell LL. Sensitization to the prosocial effects of 3,4-methylenedioxymethamphetamine (MDMA). Neuropharmacology. PMID 30922893 DOI: 10.1016/j.neuropharm.2019.03.017  0.88
2019 Maltbie EA, Gopinath KS, Howell LL. Effects of ketamine treatment on cocaine-induced reinstatement and disruption of functional connectivity in unanesthetized rhesus monkeys. Psychopharmacology. PMID 30879118 DOI: 10.1007/s00213-019-05204-4  0.4
2019 Odabas-Geldiay M, Shields H, Berro LF, Rice KC, Howell LL. Effects of acute treatments with the serotonin 2A antagonist M100907 alone or in combination with the serotonin 2C agonist WAY163909 on methamphetamine self-administration in rhesus monkeys. Drug and Alcohol Dependence. 194: 252-256. PMID 30469095 DOI: 10.1016/j.drugalcdep.2018.10.018  0.88
2018 Diaz MP, Wilson ME, Howell LL. Effects of long-term high-fat food or methamphetamine intake and serotonin 2C receptors on reversal learning in female rhesus macaques. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30188516 DOI: 10.1038/s41386-018-0200-z  0.36
2018 Berro LF, Shields H, Odabas-Geldiay M, Rothbaum BO, Andersen ML, Howell LL. Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) and R(-) MDMA on actigraphy-based daytime activity and sleep parameters in rhesus monkeys. Experimental and Clinical Psychopharmacology. PMID 29939048 DOI: 10.1037/pha0000196  0.8
2018 Young MB, Howell LL, Hopkins L, Moshfegh C, Yu Z, Clubb L, Seidenberg J, Park J, Swiercz AP, Marvar PJ. A peripheral immune response to remembering trauma contributes to the maintenance of fear memory in mice. Psychoneuroendocrinology. 94: 143-151. PMID 29783162 DOI: 10.1016/j.psyneuen.2018.05.012  0.68
2017 Curry DW, Young MB, Tran AN, Daoud GE, Howell LL. Separating the agony from ecstasy: R(-)-3,4 methylenedioxymethamphetamine has prosocial and therapeutic-like effects without signs of neurotoxicity in mice. Neuropharmacology. PMID 28993129 DOI: 10.1016/j.neuropharm.2017.10.003  0.68
2017 Young MB, Norrholm SD, Khoury LM, Jovanovic T, Rauch SAM, Reiff CM, Dunlop BW, Rothbaum BO, Howell LL. Inhibition of serotonin transporters disrupts the enhancement of fear memory extinction by 3,4-methylenedioxymethamphetamine (MDMA). Psychopharmacology. PMID 28741031 DOI: 10.1007/s00213-017-4684-8  0.68
2017 Berro LF, Andersen ML, Howell LL. Assessment of tolerance to the effects of methamphetamine on daytime and nighttime activity evaluated with actigraphy in rhesus monkeys. Psychopharmacology. PMID 28589263 DOI: 10.1007/s00213-017-4654-1  0.8
2017 Berro LF, Perez Diaz M, Maltbie E, Howell LL. Effects of the serotonin 2C receptor agonist WAY163909 on the abuse-related effects and mesolimbic dopamine neurochemistry induced by abused stimulants in rhesus monkeys. Psychopharmacology. PMID 28584928 DOI: 10.1007/s00213-017-4653-2  0.68
2017 Berro LF, Andersen ML, Tufik S, Howell LL. GABAA receptor positive allosteric modulators modify the abuse-related behavioral and neurochemical effects of methamphetamine in rhesus monkeys. Neuropharmacology. PMID 28495376 DOI: 10.1016/j.neuropharm.2017.05.010  0.8
2017 Pitts EG, Minerva AR, Oliver EB, Kohn JN, Logun MT, Sulima A, Rice KC, Howell LL. 3,4-Methylenedioxymethamphetamine Increases Affiliative Behaviors in Squirrel Monkeys in a Serotonin 2A Receptor-Dependent Manner. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28425496 DOI: 10.1038/npp.2017.80  0.88
2016 Perez Diaz M, Andersen ML, Rice KC, Howell LL. Effects of a Serotonin 2C Agonist and a 2A Antagonist on Actigraphy-Based Sleep Parameters Disrupted by Methamphetamine Self-Administration in Rhesus Monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27986974 DOI: 10.1038/npp.2016.280  0.88
2016 Berro LF, Andersen ML, Tufik S, Howell LL. Actigraphy-Based Sleep Parameters During the Reinstatement of Methamphetamine Self-Administration in Rhesus Monkeys. Experimental and Clinical Psychopharmacology. PMID 26882419 DOI: 10.1037/pha0000064  1
2015 Young MB, Andero R, Ressler KJ, Howell LL. 3,4-Methylenedioxymethamphetamine facilitates fear extinction learning. Translational Psychiatry. 5: e634. PMID 26371762 DOI: 10.1038/tp.2015.138  1
2015 Zhang X, Tong F, Li CX, Yan Y, Kempf D, Nair G, Wang S, Muly EC, Zola S, Howell L. Temporal evolution of ischemic lesions in nonhuman primates: a diffusion and perfusion MRI study. Plos One. 10: e0117290. PMID 25659092 DOI: 10.1371/journal.pone.0117290  0.32
2015 Murnane KS, Gopinath KS, Maltbie E, Daunais JB, Telesford QK, Howell LL. Functional connectivity in frontal-striatal brain networks and cocaine self-administration in female rhesus monkeys. Psychopharmacology. 232: 745-54. PMID 25138647 DOI: 10.1007/s00213-014-3709-9  1
2015 Maltbie E, Gopinath K, Urushino N, Kempf D, Howell L. Ketamine-induced brain activation in awake female nonhuman primates: a translational functional imaging model Psychopharmacology. 1-12. DOI: 10.1007/s00213-015-4175-8  1
2014 Howell LL, Nye JA, Stehouwer JS, Voll RJ, Mun J, Narasimhan D, Nichols J, Sunahara R, Goodman MM, Carroll FI, Woods JH. A thermostable bacterial cocaine esterase rapidly eliminates cocaine from brain in nonhuman primates. Translational Psychiatry. 4: e407. PMID 24984194 DOI: 10.1038/tp.2014.48  1
2014 Cooper DA, Kimmel HL, Manvich DF, Schmidt KT, Weinshenker D, Howell LL. Effects of pharmacologic dopamine β-hydroxylase inhibition on cocaine-induced reinstatement and dopamine neurochemistry in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 350: 144-52. PMID 24817036 DOI: 10.1124/jpet.113.212357  1
2014 Howell LL, Negus SS. Monoamine transporter inhibitors and substrates as treatments for stimulant abuse. Advances in Pharmacology (San Diego, Calif.). 69: 129-76. PMID 24484977 DOI: 10.1016/B978-0-12-420118-7.00004-4  1
2013 McIntosh S, Howell L, Hemby SE. Dopaminergic dysregulation in prefrontal cortex of rhesus monkeys following cocaine self-administration. Frontiers in Psychiatry. 4: 88. PMID 23970867 DOI: 10.3389/fpsyt.2013.00088  1
2013 Murnane KS, Winschel J, Schmidt KT, Stewart LM, Rose SJ, Cheng K, Rice KC, Howell LL. Serotonin 2A receptors differentially contribute to abuse-related effects of cocaine and cocaine-induced nigrostriatal and mesolimbic dopamine overflow in nonhuman primates. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13367-74. PMID 23946394 DOI: 10.1523/JNEUROSCI.1437-13.2013  1
2013 Murnane KS, Andersen ML, Rice KC, Howell LL. Selective serotonin 2A receptor antagonism attenuates the effects of amphetamine on arousal and dopamine overflow in non-human primates. Journal of Sleep Research. 22: 581-8. PMID 23879373 DOI: 10.1111/jsr.12045  1
2013 Howell L. Reply to Dr. Kawada's letter Psychopharmacology. 228: 511. PMID 23779258 DOI: 10.1007/s00213-013-3171-0  1
2013 Chen J, Repunte-Canonigo V, Kawamura T, Lefebvre C, Shin W, Howell LL, Hemby SE, Harvey BK, Califano A, Morales M, Koob GF, Sanna PP. Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor. Nature Communications. 4: 1955. PMID 23736082 DOI: 10.1038/ncomms2955  1
2013 Felger JC, Mun J, Kimmel HL, Nye JA, Drake DF, Hernandez CR, Freeman AA, Rye DB, Goodman MM, Howell LL, Miller AH. Chronic interferon-α decreases dopamine 2 receptor binding and striatal dopamine release in association with anhedonia-like behavior in nonhuman primates. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2179-87. PMID 23657438 DOI: 10.1038/npp.2013.115  1
2013 Andersen ML, Diaz MP, Murnane KS, Howell LL. Effects of methamphetamine self-administration on actigraphy-based sleep parameters in rhesus monkeys. Psychopharmacology. 227: 101-7. PMID 23263461 DOI: 10.1007/s00213-012-2943-2  1
2012 Manvich DF, Kimmel HL, Cooper DA, Howell LL. The serotonin 2C receptor antagonist SB 242084 exhibits abuse-related effects typical of stimulants in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 342: 761-9. PMID 22685342 DOI: 10.1124/jpet.112.195156  1
2012 Sawyer EK, Mun J, Nye JA, Kimmel HL, Voll RJ, Stehouwer JS, Rice KC, Goodman MM, Howell LL. Neurobiological changes mediating the effects of chronic fluoxetine on cocaine use. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1816-24. PMID 22434223 DOI: 10.1038/npp.2012.29  1
2012 Manvich DF, Kimmel HL, Howell LL. Effects of serotonin 2C receptor agonists on the behavioral and neurochemical effects of cocaine in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 341: 424-34. PMID 22328576 DOI: 10.1124/jpet.111.186981  1
2012 Bauzo RM, Kimmel HL, Howell LL. The cystine-glutamate transporter enhancer N-acetyl-L-cysteine attenuates cocaine-induced changes in striatal dopamine but not self-administration in squirrel monkeys. Pharmacology, Biochemistry, and Behavior. 101: 288-96. PMID 22244740 DOI: 10.1016/j.pbb.2011.12.018  1
2012 Kimmel HL, Nye JA, Voll R, Mun J, Stehouwer J, Goodman MM, Votaw JR, Carroll FI, Howell LL. Simultaneous measurement of extracellular dopamine and dopamine transporter occupancy by cocaine analogs in squirrel monkeys. Synapse (New York, N.Y.). 66: 501-8. PMID 22237864 DOI: 10.1002/syn.21536  1
2012 Muly EC, Votaw JR, Ritchie J, Howell LL. Relationship between dose, drug levels, and D2 receptor occupancy for the atypical antipsychotics risperidone and paliperidone. The Journal of Pharmacology and Experimental Therapeutics. 341: 81-9. PMID 22214649 DOI: 10.1124/jpet.111.189076  1
2012 Murnane KS, Kimmel HL, Rice KC, Howell LL. The neuropharmacology of prolactin secretion elicited by 3,4-methylenedioxymethamphetamine ("ecstasy"): a concurrent microdialysis and plasma analysis study. Hormones and Behavior. 61: 181-90. PMID 22197270 DOI: 10.1016/j.yhbeh.2011.10.012  1
2012 Andersen ML, Sawyer EK, Carroll FI, Howell LL. Influence of chronic dopamine transporter inhibition by RTI-336 on motor behavior, sleep, and hormone levels in rhesus monkeys. Experimental and Clinical Psychopharmacology. 20: 77-83. PMID 22023668 DOI: 10.1037/a0026034  1
2012 Murnane KS, Perrine SA, Finton BJ, Galloway MP, Howell LL, Fantegrossi WE. Effects of exposure to amphetamine derivatives on passive avoidance performance and the central levels of monoamines and their metabolites in mice: correlations between behavior and neurochemistry. Psychopharmacology. 220: 495-508. PMID 21993877 DOI: 10.1007/s00213-011-2504-0  1
2012 Andersen ML, Sawyer EK, Howell LL. Contributions of neuroimaging to understanding sex differences in cocaine abuse. Experimental and Clinical Psychopharmacology. 20: 2-15. PMID 21875225 DOI: 10.1037/a0025219  1
2011 Sawyer EK, Howell LL. Pharmacokinetics of fluoxetine in rhesus macaques following multiple routes of administration. Pharmacology. 88: 44-9. PMID 21757974 DOI: 10.1159/000329417  1
2011 Murnane KS, Howell LL. Neuroimaging and drug taking in primates. Psychopharmacology. 216: 153-71. PMID 21360099 DOI: 10.1007/s00213-011-2222-7  1
2011 Howell LL, Murnane KS. Nonhuman primate positron emission tomography neuroimaging in drug abuse research. The Journal of Pharmacology and Experimental Therapeutics. 337: 324-34. PMID 21317354 DOI: 10.1124/jpet.108.136689  1
2010 Masilamoni G, Votaw J, Howell L, Villalba RM, Goodman M, Voll RJ, Stehouwer J, Wichmann T, Smith Y. (18)F-FECNT: validation as PET dopamine transporter ligand in parkinsonism. Experimental Neurology. 226: 265-73. PMID 20832405 DOI: 10.1016/j.expneurol.2010.08.024  1
2010 Henry PK, Murnane KS, Votaw JR, Howell LL. Acute brain metabolic effects of cocaine in rhesus monkeys with a history of cocaine use. Brain Imaging and Behavior. 4: 212-9. PMID 20680706 DOI: 10.1007/s11682-010-9100-5  1
2010 Stehouwer JS, Daniel LM, Chen P, Voll RJ, Williams L, Plott SJ, Votaw JR, Owens MJ, Howell L, Goodman MM. Synthesis, fluorine-18 radiolabeling, and biological evaluation of N-((E)-4-fluorobut-2-en-1-yl)-2beta-carbomethoxy-3beta-(4'-halophenyl)nortropanes: candidate radioligands for in vivo imaging of the brain dopamine transporter with positron emission tomography. Journal of Medicinal Chemistry. 53: 5549-57. PMID 20597489 DOI: 10.1021/jm100269c  1
2010 Murnane KS, Howell LL. Development of an apparatus and methodology for conducting functional magnetic resonance imaging (fMRI) with pharmacological stimuli in conscious rhesus monkeys. Journal of Neuroscience Methods. 191: 11-20. PMID 20566353 DOI: 10.1016/j.jneumeth.2010.06.001  1
2010 Murnane KS, Fantegrossi WE, Godfrey JR, Banks ML, Howell LL. Endocrine and neurochemical effects of 3,4-methylenedioxymethamphetamine and its stereoisomers in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 334: 642-50. PMID 20466795 DOI: 10.1124/jpet.110.166595  1
2010 Andersen ML, Kessler E, Murnane KS, McClung JC, Tufik S, Howell LL. Dopamine transporter-related effects of modafinil in rhesus monkeys. Psychopharmacology. 210: 439-48. PMID 20386883 DOI: 10.1007/s00213-010-1839-2  1
2010 McClung J, Fantegrossi W, Howell LL. Reinstatement of extinguished amphetamine self-administration by 3,4-methylenedioxymethamphetamine (MDMA) and its enantiomers in rhesus monkeys. Psychopharmacology. 210: 75-83. PMID 20309529 DOI: 10.1007/s00213-010-1818-7  1
2010 Ewing Corcoran SB, Howell LL. Impact of early life stress on the reinforcing and behavioral-stimulant effects of psychostimulants in rhesus monkeys. Behavioural Pharmacology. 21: 69-76. PMID 20016373 DOI: 10.1097/FBP.0b013e3283359f53  1
2010 Howell LL, Votaw JR, Goodman MM, Lindsey KP. Cortical activation during cocaine use and extinction in rhesus monkeys. Psychopharmacology. 208: 191-9. PMID 19924404 DOI: 10.1007/s00213-009-1720-3  1
2010 Tannu NS, Howell LL, Hemby SE. Integrative proteomic analysis of the nucleus accumbens in rhesus monkeys following cocaine self-administration. Molecular Psychiatry. 15: 185-203. PMID 18504425 DOI: 10.1038/mp.2008.53  1
2009 Kimmel HL, Manvich DF, Blough BE, Negus SS, Howell LL. Behavioral and neurochemical effects of amphetamine analogs that release monoamines in the squirrel monkey. Pharmacology, Biochemistry, and Behavior. 94: 278-84. PMID 19766133 DOI: 10.1016/j.pbb.2009.09.007  1
2009 Bauzo RM, Kimmel HL, Howell LL. Interactions between the mGluR2/3 agonist, LY379268, and cocaine on in vivo neurochemistry and behavior in squirrel monkeys. Pharmacology, Biochemistry, and Behavior. 94: 204-10. PMID 19703487 DOI: 10.1016/j.pbb.2009.08.011  1
2009 Murnane KS, Murai N, Howell LL, Fantegrossi WE. Discriminative stimulus effects of psychostimulants and hallucinogens in S(+)-3,4-methylenedioxymethamphetamine (MDMA) and R(-)-MDMA trained mice. The Journal of Pharmacology and Experimental Therapeutics. 331: 717-23. PMID 19684254 DOI: 10.1124/jpet.109.156174  1
2009 Banks ML, Andersen ML, Murnane KS, Meyer RC, Howell LL. Behavioral and neurochemical effects of cocaine and diphenhydramine combinations in rhesus monkeys. Psychopharmacology. 205: 467-74. PMID 19430765 DOI: 10.1007/s00213-009-1555-y  1
2009 Fantegrossi WE, Bauzo RM, Manvich DM, Morales JC, Votaw JR, Goodman MM, Howell LL. Role of dopamine transporters in the behavioral effects of 3,4-methylenedioxymethamphetamine (MDMA) in nonhuman primates. Psychopharmacology. 205: 337-47. PMID 19421742 DOI: 10.1007/s00213-009-1545-0  1
2009 Kirkland Henry P, Davis M, Howell LL. Effects of cocaine self-administration history under limited and extended access conditions on in vivo striatal dopamine neurochemistry and acoustic startle in rhesus monkeys. Psychopharmacology. 205: 237-47. PMID 19365621 DOI: 10.1007/s00213-009-1534-3  1
2009 Henry PK, Howell LL. Cocaine-induced reinstatement during limited and extended drug access conditions in rhesus monkeys. Psychopharmacology. 204: 523-9. PMID 19221719 DOI: 10.1007/s00213-009-1485-8  1
2009 Banks ML, Manvich DF, Bauzo RM, Howell LL. Effects of histamine H(3) receptor activation on the behavioral-stimulant effects of methamphetamine and cocaine in mice and squirrel monkeys. Pharmacology. 83: 164-9. PMID 19145102 DOI: 10.1159/000191473  1
2009 Zeng F, Mun J, Jarkas N, Stehouwer JS, Voll RJ, Tamagnan GD, Howell L, Votaw JR, Kilts CD, Nemeroff CB, Goodman MM. Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 labeled reboxetine analogues: potential positron emission tomography radioligands for in vivo imaging of the norepinephrine transporter. Journal of Medicinal Chemistry. 52: 62-73. PMID 19067522 DOI: 10.1021/jm800817h  1
2009 Negus SS, Mello NK, Kimmel HL, Howell LL, Carroll FI. Effects of the monoamine uptake inhibitors RTI-112 and RTI-113 on cocaine- and food-maintained responding in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 91: 333-8. PMID 18755212 DOI: 10.1016/j.pbb.2008.08.002  1
2008 Howell LL. Nonhuman primate neuroimaging and cocaine medication development. Experimental and Clinical Psychopharmacology. 16: 446-57. PMID 19086766 DOI: 10.1037/a0014196  1
2008 Stehouwer JS, Jarkas N, Zeng F, Voll RJ, Williams L, Camp VM, Malveaux EJ, Votaw JR, Howell L, Owens MJ, Goodman MM. Synthesis, radiosynthesis, and biological evaluation of fluorine-18-labeled 2beta-carbo(fluoroalkoxy)-3beta-(3'-((Z)-2-haloethenyl)phenyl)nortropanes: candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomography. Journal of Medicinal Chemistry. 51: 7788-99. PMID 19053782 DOI: 10.1021/jm800781a  1
2008 Howell LL, Murnane KS. Nonhuman primate neuroimaging and the neurobiology of psychostimulant addiction. Annals of the New York Academy of Sciences. 1141: 176-94. PMID 18991958 DOI: 10.1196/annals.1441.023  1
2008 Kimmel HL, Negus SS, Wilcox KM, Ewing SB, Stehouwer J, Goodman MM, Votaw JR, Mello NK, Carroll FI, Howell LL. Relationship between rate of drug uptake in brain and behavioral pharmacology of monoamine transporter inhibitors in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 90: 453-62. PMID 18468667 DOI: 10.1016/j.pbb.2008.03.032  1
2008 Howell LL, Kimmel HL. Monoamine transporters and psychostimulant addiction. Biochemical Pharmacology. 75: 196-217. PMID 17825265 DOI: 10.1016/j.bcp.2007.08.003  1
2008 Carroll FI, Howard JL, Howell LL, Fox BS, Kuhar MJ. Development of the dopamine transporter selective RTI-336 as a pharmacotherapy for cocaine abuse Drug Addiction: From Basic Research to Therapy. 179-191. DOI: 10.1007/978-0-387-76678-2_12  1
2007 Plisson C, Stehouwer JS, Voll RJ, Howell L, Votaw JR, Owens MJ, Goodman MM. Synthesis and in vivo evaluation of fluorine-18 and iodine-123 labeled 2beta-carbo(2-fluoroethoxy)-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane as a candidate serotonin transporter imaging agent. Journal of Medicinal Chemistry. 50: 4553-60. PMID 17705359 DOI: 10.1021/jm061303s  1
2007 Kimmel HL, O'Connor JA, Carroll FI, Howell LL. Faster onset and dopamine transporter selectivity predict stimulant and reinforcing effects of cocaine analogs in squirrel monkeys. Pharmacology, Biochemistry, and Behavior. 86: 45-54. PMID 17258302 DOI: 10.1016/j.pbb.2006.12.006  1
2007 Howell LL, Carroll FI, Votaw JR, Goodman MM, Kimmel HL. Effects of combined dopamine and serotonin transporter inhibitors on cocaine self-administration in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 320: 757-65. PMID 17105829 DOI: 10.1124/jpet.106.108324  1
2006 Carroll FI, Howard JL, Howell LL, Fox BS, Kuhar MJ. Development of the dopamine transporter selective RTI-336 as a pharmacotherapy for cocaine abuse. The Aaps Journal. 8: E196-203. PMID 16584128 DOI: 10.1208/aapsj080124  1
2006 Plisson C, Jarkas N, McConathy J, Voll RJ, Votaw J, Williams L, Howell LL, Kilts CD, Goodman MM. Evaluation of carbon-11-labeled 2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)phenyl]nortropane as a potential radioligand for imaging the serotonin transporter by PET. Journal of Medicinal Chemistry. 49: 942-6. PMID 16451060 DOI: 10.1021/jm050799v  1
2006 Howell LL, Wilcox KM, Lindsey KP, Kimmel HL. Olanzapine-induced suppression of cocaine self-administration in rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 585-93. PMID 16052248 DOI: 10.1038/sj.npp.1300828  1
2005 Hemby SE, Tang W, Muly EC, Kuhar MJ, Howell L, Mash DC. Cocaine-induced alterations in nucleus accumbens ionotropic glutamate receptor subunits in human and non-human primates. Journal of Neurochemistry. 95: 1785-93. PMID 16363995 DOI: 10.1111/j.1471-4159.2005.03517.x  1
2005 Wilcox KM, Kimmel HL, Lindsey KP, Votaw JR, Goodman MM, Howell LL. In vivo comparison of the reinforcing and dopamine transporter effects of local anesthetics in rhesus monkeys. Synapse (New York, N.Y.). 58: 220-8. PMID 16206183 DOI: 10.1002/syn.20199  1
2005 Carroll FI, Blough BE, Nie Z, Kuhar MJ, Howell LL, Navarro HA. Synthesis and monoamine transporter binding properties of 3beta-(3',4'-disubstituted phenyl)tropane-2beta-carboxylic acid methyl esters. Journal of Medicinal Chemistry. 48: 2767-71. PMID 15828814 DOI: 10.1021/jm040185a  1
2005 Kimmel HL, Ginsburg BC, Howell LL. Changes in extracellular dopamine during cocaine self-administration in squirrel monkeys. Synapse (New York, N.Y.). 56: 129-34. PMID 15765537 DOI: 10.1002/syn.20135  1
2005 Ginsburg BC, Kimmel HL, Carroll FI, Goodman MM, Howell LL. Interaction of cocaine and dopamine transporter inhibitors on behavior and neurochemistry in monkeys. Pharmacology, Biochemistry, and Behavior. 80: 481-91. PMID 15740791 DOI: 10.1016/j.pbb.2005.01.004  1
2004 Lindsey KP, Wilcox KM, Votaw JR, Goodman MM, Plisson C, Carroll FI, Rice KC, Howell LL. Effects of dopamine transporter inhibitors on cocaine self-administration in rhesus monkeys: relationship to transporter occupancy determined by positron emission tomography neuroimaging. The Journal of Pharmacology and Experimental Therapeutics. 309: 959-69. PMID 14982963 DOI: 10.1124/jpet.103.060293  1
2003 Goodman MM, Chen P, Plisson C, Martarello L, Galt J, Votaw JR, Kilts CD, Malveaux G, Camp VM, Shi B, Ely TD, Howell L, McConathy J, Nemeroff CB. Synthesis and characterization of iodine-123 labeled 2beta-carbomethoxy-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane. A ligand for in vivo imaging of serotonin transporters by single-photon-emission tomography. Journal of Medicinal Chemistry. 46: 925-35. PMID 12620070 DOI: 10.1021/jm0100180  1
2002 Howell LL, Wilcox KM. Functional imaging and neurochemical correlates of stimulant self-administration in primates. Psychopharmacology. 163: 352-61. PMID 12373436 DOI: 10.1007/s00213-002-1207-y  1
2002 Votaw JR, Howell LL, Martarello L, Hoffman JM, Kilts CD, Lindsey KP, Goodman MM. Measurement of dopamine transporter occupancy for multiple injections of cocaine using a single injection of [F-18]FECNT. Synapse (New York, N.Y.). 44: 203-10. PMID 11984856 DOI: 10.1002/syn.10068  1
2002 Howell LL, Hoffman JM, Votaw JR, Landrum AM, Wilcox KM, Lindsey KP. Cocaine-induced brain activation determined by positron emission tomography neuroimaging in conscious rhesus monkeys. Psychopharmacology. 159: 154-60. PMID 11862343 DOI: 10.1007/s002130100911  1
2002 Czoty PW, Ginsburg BC, Howell LL. Serotonergic attenuation of the reinforcing and neurochemical effects of cocaine in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 300: 831-7. PMID 11861788 DOI: 10.1124/jpet.300.3.831  1
2002 Wilcox KM, Lindsey KP, Votaw JR, Goodman MM, Martarello L, Carroll FI, Howell LL. Self-administration of cocaine and the cocaine analog RTI-113: relationship to dopamine transporter occupancy determined by PET neuroimaging in rhesus monkeys. Synapse (New York, N.Y.). 43: 78-85. PMID 11746736 DOI: 10.1002/syn.10018  1
2001 Howell LL, Wilcox KM. The dopamine transporter and cocaine medication development: drug self-administration in nonhuman primates. The Journal of Pharmacology and Experimental Therapeutics. 298: 1-6. PMID 11408518  1
2001 Howell LL, Schama KF, Ellis JE, Grimley PJ, Kitchens AJ, Byrd LD. Fetal development in rhesus monkeys exposed prenatally to cocaine. Neurotoxicology and Teratology. 23: 133-40. PMID 11348830 DOI: 10.1016/S0892-0362(01)00121-0  1
2001 Howell LL, Hoffman JM, Votaw JR, Landrum AM, Jordan JF. An apparatus and behavioral training protocol to conduct positron emission tomography (PET) neuroimaging in conscious rhesus monkeys. Journal of Neuroscience Methods. 106: 161-9. PMID 11325436 DOI: 10.1016/S0165-0270(01)00345-4  1
2000 Howell LL, Byrd LD, Mcdonough AM, Iuvone PM, Bakay RAE. Behavioral Evaluation of Hemiparkinsonian MPTP Monkeys following Dopamine Pharmacological Manipulation and Adrenal Co-Graft Transplantation. Cell Transplantation. 9: 609-622. PMID 28880666 DOI: 10.1177/096368970000900506  0.76
2000 Howel LL, Byrd LD, McDonough AM, Iuvone PM, Bakay RA. Behavioral evaluation of hemiparkinsonian MPTP monkeys following dopamine pharmacological manipulation and adrenal co-graft transplantation. Cell Transplantation. 9: 609-22. PMID 11144958  1
2000 Czoty PW, Howell LL. Behavioral effects of AMI-193, a 5-HT(2A)- and dopamine D(2)-receptor antagonist, in the squirrel monkey. Pharmacology, Biochemistry, and Behavior. 67: 257-64. PMID 11124389 DOI: 10.1016/S0091-3057(00)00321-X  1
2000 Czoty PW, Justice JB, Howell LL. Cocaine-induced changes in extracellular dopamine determined by microdialysis in awake squirrel monkeys. Psychopharmacology. 148: 299-306. PMID 10755743  1
2000 Howell LL, Czoty PW, Kuhar MJ, Carrol FI. Comparative behavioral pharmacology of cocaine and the selective dopamine uptake inhibitor RTI-113 in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 292: 521-9. PMID 10640288  1
1999 Carroll FI, Howell LL, Kuhar MJ. Pharmacotherapies for treatment of cocaine abuse: preclinical aspects. Journal of Medicinal Chemistry. 42: 2721-36. PMID 10425082 DOI: 10.1021/jm9706729  1
1997 Howell LL, Landrum AM. Effects of chronic caffeine administration on respiration and schedule-controlled behavior in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 283: 190-9. PMID 9336324  1
1997 Schama KF, Howell LL, Byrd LD. Serotonergic modulation of the discriminative-stimulus effects of cocaine in squirrel monkeys. Psychopharmacology. 132: 27-34. PMID 9272756 DOI: 10.1007/s002130050316  1
1997 Howell LL, Czoty PW, Byrd LD. Pharmacological interactions between serotonin and dopamine on behavior in the squirrel monkey. Psychopharmacology. 131: 40-8. PMID 9181634 DOI: 10.1007/s002130050263  1
1997 Howell LL, Coffin VL, Spealman RD. Behavioral and physiological effects of xanthines in nonhuman primates. Psychopharmacology. 129: 1-14. PMID 9122357 DOI: 10.1007/s002130050155  1
1997 Howell LL, Landrum AM. Effects of chronic caffeine administration on respiration and schedule- controlled behavior in rhesus monkeys Journal of Pharmacology and Experimental Therapeutics. 283: 190-199.  1
1995 Howell LL, Byrd LD. Serotonergic modulation of the behavioral effects of cocaine in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 275: 1551-9. PMID 8531128  1
1995 Howell LL. Effects of caffeine on ventilation during acute and chronic nicotine administration in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 273: 1085-94. PMID 7791079  1
1995 Howell LL, Landrum AM. Attenuation of hypoxia-induced increases in ventilation by adenosine antagonists in rhesus monkeys. Life Sciences. 57: 773-83. PMID 7637551 DOI: 10.1016/0024-3205(95)02005-4  1
1994 Howell LL, Landrum AM. Behavioral and pharmacological modulation of respiration in rhesus monkeys. Journal of the Experimental Analysis of Behavior. 62: 57-72. PMID 8064213 DOI: 10.1901/jeab.1994.62-57  1
1993 Howell LL. Effects of adenosine agonists on ventilation during hypercapnia, hypoxia and hyperoxia in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 265: 971-8. PMID 8496837  1
1993 Howell LL, Byrd LD. Effects of CGS 15943, a nonxanthine adenosine antagonist, on behavior in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 267: 432-9. PMID 8229772  1
1993 Howell LL. Comparative effects of caffeine and selective phosphodiesterase inhibitors on respiration and behavior in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 266: 894-903. PMID 7689104  1
1992 Howell LL, Byrd LD. Enhanced sensitivity to the behavioral effects of cocaine after chronic administration of D2-selective dopamine antagonists in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 262: 907-15. PMID 1388204  1
1991 Howell LL, Byrd LD. Characterization of the effects of cocaine and GBR 12909, a dopamine uptake inhibitor, on behavior in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 258: 178-85. PMID 1677037  1
1990 Howell LL, Morse WH, Spealman RD. Respiratory effects of xanthines and adenosine analogs in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 254: 786-91. PMID 2395111  1
1989 Howell LL, Morse WH. Behavioral effects of chronically administered cocaine in squirrel monkeys. Psychopharmacology. 97: 12-6. PMID 2496417 DOI: 10.1007/BF00443405  1
1988 Howell LL, Byrd LD, Marr MJ. Differential effects of cocaine and pentobarbital on fixed-interval and random-interval performance. Journal of the Experimental Analysis of Behavior. 49: 411-28. PMID 3385354 DOI: 10.1901/jeab.1988.49-411  1
1988 Howell LL, Bergman J, Morse WH. Effects of levorphanol and several kappa-selective opioids on respiration and behavior in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 245: 364-72. PMID 2834543  1
1987 Byrd LD, Standish LJ, Howell LL. Behavioral effects of phencyclidine and ketamine alone and in combination with other drugs. European Journal of Pharmacology. 144: 331-41. PMID 3440479 DOI: 10.1016/0014-2999(87)90386-4  1
1986 Howell LL, Byrd LD, Marr MJ. Similarities in the rate-altering effects of white noise and cocaine. Journal of the Experimental Analysis of Behavior. 46: 381-94. PMID 3805977 DOI: 10.1901/jeab.1986.46-381  1
1984 Howell LL, Standish LJ, Byrd LD. Behavioral effects of PCP and ketamine in combination with several antagonists Federation Proceedings. 43: no. 3909.  1
1983 Howell LL, Byrd LD, Marr MJ. An interresponse-time analysis of responding maintained by schedules of response-produced electric shock. Journal of the Experimental Analysis of Behavior. 40: 165-77. PMID 16812341  0.76
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