| Year |
Citation |
Score |
| 2023 |
Im E, Jiang Y, Stavrides PH, Darji S, Erdjument-Bromage H, Neubert TA, Choi JY, Wegiel J, Lee JH, Nixon RA. Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr-phosphorylated APP βCTF. Science Advances. 9: eadg1925. PMID 37494443 DOI: 10.1126/sciadv.adg1925 |
0.539 |
|
| 2022 |
Rao MV, Darji S, Stavrides PH, Goulbourne CN, Kumar A, Yang DS, Yoo L, Peddy J, Lee JH, Yuan A, Nixon RA. Autophagy is a novel pathway for neurofilament protein degradation . Autophagy. 1-16. PMID 36131358 DOI: 10.1080/15548627.2022.2124500 |
0.471 |
|
| 2022 |
Lee JH, Nixon RA. Autolysosomal acidification failure as a primary driver of Alzheimer disease pathogenesis. Autophagy. 1-2. PMID 35947489 DOI: 10.1080/15548627.2022.2110729 |
0.572 |
|
| 2022 |
Lee JH, Yang DS, Goulbourne CN, Im E, Stavrides P, Pensalfini A, Chan H, Bouchet-Marquis C, Bleiwas C, Berg MJ, Huo C, Peddy J, Pawlik M, Levy E, Rao M, et al. Faulty autolysosome acidification in Alzheimer's disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques. Nature Neuroscience. 25: 688-701. PMID 35654956 DOI: 10.1038/s41593-022-01084-8 |
0.578 |
|
| 2022 |
Lie PPY, Yoo L, Goulbourne CN, Berg MJ, Stavrides P, Huo C, Lee JH, Nixon RA. Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca efflux and disrupted by PSEN1 loss of function. Science Advances. 8: eabj5716. PMID 35486730 DOI: 10.1126/sciadv.abj5716 |
0.493 |
|
| 2020 |
Pensalfini A, Kim S, Subbanna S, Bleiwas C, Goulbourne CN, Stavrides PH, Jiang Y, Lee JH, Darji S, Pawlik M, Huo C, Peddy J, Berg MJ, Smiley JF, Basavarajappa BS, et al. Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease. Cell Reports. 33: 108420. PMID 33238112 DOI: 10.1016/j.celrep.2020.108420 |
0.723 |
|
| 2020 |
Lee JH, Wolfe DM, Darji S, McBrayer MK, Colacurcio DJ, Kumar A, Stavrides P, Mohan PS, Nixon RA. β2-adrenergic agonists rescue lysosome acidification and function in PSEN1 deficiency by reversing defective ER to lysosome delivery of ClC-7. Journal of Molecular Biology. PMID 32105735 DOI: 10.1016/J.Jmb.2020.02.021 |
0.564 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Lee JK, ... ... Lee J, ... ... Lee JH, ... ... Lee JH, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886 |
0.447 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... Lee JK, ... Lee J, ... Lee JH, ... Lee JH, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.51 |
|
| 2015 |
Lee JH, McBrayer MK, Wolfe DM, Haslett LJ, Kumar A, Sato Y, Lie PP, Mohan P, Coffey EE, Kompella U, Mitchell CH, Lloyd-Evans E, Nixon RA. Presenilin 1 Maintains Lysosomal Ca(2+) Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification. Cell Reports. PMID 26299959 DOI: 10.1016/J.Celrep.2015.07.050 |
0.536 |
|
| 2015 |
Yuan A, Sershen H, Veeranna, Basavarajappa BS, Kumar A, Hashim A, Berg M, Lee JH, Sato Y, Rao MV, Mohan PS, Dyakin V, Julien JP, Lee VM, Nixon RA. Neurofilament subunits are integral components of synapses and modulate neurotransmission and behavior in vivo. Molecular Psychiatry. PMID 25869803 DOI: 10.1038/Mp.2015.45 |
0.426 |
|
| 2013 |
Wolfe DM, Lee JH, Kumar A, Lee S, Orenstein SJ, Nixon RA. Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification. The European Journal of Neuroscience. 37: 1949-61. PMID 23773064 DOI: 10.1111/Ejn.12169 |
0.584 |
|
| 2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Lee J, ... ... Lee JH, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.488 |
|
| 2011 |
Veeranna, Yang DS, Lee JH, Vinod KY, Stavrides P, Amin ND, Pant HC, Nixon RA. Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments. Neurobiology of Aging. 32: 2016-29. PMID 20031277 DOI: 10.1016/J.Neurobiolaging.2009.12.001 |
0.522 |
|
| 2010 |
Lee JH, Yu WH, Kumar A, Lee S, Mohan PS, Peterhoff CM, Wolfe DM, Martinez-Vicente M, Massey AC, Sovak G, Uchiyama Y, Westaway D, Cuervo AM, Nixon RA. Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations. Cell. 141: 1146-58. PMID 20541250 DOI: 10.1016/J.Cell.2010.05.008 |
0.579 |
|
| 2010 |
Lee J, Yu WH, Kumar A, Lee S, Mohan PS, Peterhoff CM, Martinez-Vicente M, Massey AC, Sovak G, Uchiyama Y, Westaway D, Sisodia SS, Cuervo AM, Nixon RA. P2-271: Presenilin 1 (PS1) is required for lysosome acidification: FAD mutations of PS1 cause loss of protein turnover by autophagy Alzheimer's & Dementia. 6: S393-S394. DOI: 10.1016/J.Jalz.2010.05.1321 |
0.508 |
|
| 2009 |
Yang DS, Lee JH, Nixon RA. Monitoring autophagy in Alzheimer's disease and related neurodegenerative diseases. Methods in Enzymology. 453: 111-44. PMID 19216904 DOI: 10.1016/S0076-6879(08)04006-8 |
0.528 |
|
| 2008 |
Veeranna, Lee JH, Pareek TK, Jaffee H, Boland B, Vinod KY, Amin N, Kulkarni AB, Pant HC, Nixon RA. Neurofilament tail phosphorylation: identity of the RT-97 phosphoepitope and regulation in neurons by cross-talk among proline-directed kinases. Journal of Neurochemistry. 107: 35-49. PMID 18715269 DOI: 10.1111/J.1471-4159.2008.05547.X |
0.501 |
|
| 2008 |
Nixon RA, Yang DS, Lee JH. Neurodegenerative lysosomal disorders: a continuum from development to late age. Autophagy. 4: 590-9. PMID 18497567 DOI: 10.4161/Auto.6259 |
0.566 |
|
| 2006 |
Yu WH, Lee J, Massey A, Peterhoff C, Kumar A, Mohan P, Cuervo AM, Nixon RA. O3-03-07: Presenilin-1 is required for macroautophagy: PS1 mutations causing AD confer loss of macroautophagy function Alzheimer's & Dementia. 2: S58-S58. DOI: 10.1016/J.Jalz.2006.05.211 |
0.519 |
|
| 2005 |
Yu WH, Cuervo AM, Kumar A, Peterhoff CM, Schmidt SD, Lee JH, Mohan PS, Mercken M, Farmery MR, Tjernberg LO, Jiang Y, Duff K, Uchiyama Y, Näslund J, Mathews PM, et al. Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease. The Journal of Cell Biology. 171: 87-98. PMID 16203860 DOI: 10.1083/Jcb.200505082 |
0.663 |
|
| 2004 |
Lee JH, Lau KF, Perkinton MS, Standen CL, Rogelj B, Falinska A, McLoughlin DM, Miller CC. The neuronal adaptor protein X11beta reduces amyloid beta-protein levels and amyloid plaque formation in the brains of transgenic mice. The Journal of Biological Chemistry. 279: 49099-104. PMID 15347685 DOI: 10.1074/Jbc.M405602200 |
0.66 |
|
| 2003 |
Lee JH, Lau KF, Perkinton MS, Standen CL, Shemilt SJ, Mercken L, Cooper JD, McLoughlin DM, Miller CC. The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice. The Journal of Biological Chemistry. 278: 47025-9. PMID 12970358 DOI: 10.1074/Jbc.M300503200 |
0.627 |
|
| 2000 |
Shin HJ, Lee EK, Lee JH, Lee D, Chang CS, Kim YS, Paik SR. Eosin interaction of alpha-synuclein leading to protein self-oligomerization. Biochimica Et Biophysica Acta. 1481: 139-46. PMID 11004584 DOI: 10.1016/S0167-4838(00)00106-0 |
0.434 |
|
| 2000 |
Paik SR, Shin HJ, Lee JH. Metal-catalyzed oxidation of alpha-synuclein in the presence of Copper(II) and hydrogen peroxide. Archives of Biochemistry and Biophysics. 378: 269-77. PMID 10860544 DOI: 10.1006/abbi.2000.1822 |
0.483 |
|
| 1999 |
PAIK SR, SHIN H, LEE J, CHANG C, KIM J. Copper(II)-induced self-oligomerization of α-synuclein Biochemical Journal. 340: 821. DOI: 10.1042/0264-6021:3400821 |
0.416 |
|
| 1998 |
Lee JH, Shin HJ, Chang CS, Paik SR. Comparisons of the NACP self-oligomerizations induced by Abeta25-35 in the presence of dicyclohexylcarbodiimide and N-(ethoxycarbonyl)-2-ethoxy-1,2-dihydroquinoline. Neurochemical Research. 23: 1427-34. PMID 9814554 DOI: 10.1023/A:1020711025418 |
0.558 |
|
| 1998 |
Paik SR, Lee JH, Kim DH, Chang CS, Kim YS. Self-oligomerization of NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer's disease amyloid, observed in the presence of a C-terminal A beta fragment (residues 25-35). Febs Letters. 421: 73-6. PMID 9462843 DOI: 10.1016/S0014-5793(97)01537-8 |
0.504 |
|
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