Carmen Vale - Publications

Affiliations: 
Universidad de Santiago de Compostela, Santiago de Compostela, Galicia, Spain 

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Martín V, Vale C, Rubiolo JA, Roel M, Hirama M, Yamashita S, Vieytes MR, Botana LM. Chronic Ciguatoxin Treatment Induces Synaptic Scaling through Voltage Gated Sodium Channels in Cortical Neurons. Chemical Research in Toxicology. 28: 1109-19. PMID 25945544 DOI: 10.1021/tx500506q  1
2015 Martín V, Vale C, Hirama M, Yamashita S, Rubiolo JA, Vieytes MR, Botana LM. Synthetic Ciguatoxin CTX 3C Induces a Rapid Imbalance in Neuronal Excitability. Chemical Research in Toxicology. 28: 1095-108. PMID 25945403 DOI: 10.1021/tx500503d  1
2015 Rubiolo JA, Vale C, Martín V, Fuwa H, Sasaki M, Botana LM. Potassium currents inhibition by gambierol analogs prevents human T lymphocyte activation. Archives of Toxicology. 89: 1119-34. PMID 25155189 DOI: 10.1007/s00204-014-1299-2  1
2014 Audoin C, Sánchez JA, Genta-Jouve G, Alfonso A, Rios L, Vale C, Thomas OP, Botana LM. Autumnalamide, a prenylated cyclic peptide from the cyanobacterium Phormidium autumnale, acts on SH-SY5Y cells at the mitochondrial level. Journal of Natural Products. 77: 2196-205. PMID 25265024 DOI: 10.1021/np500374a  1
2014 Martin V, Vale C, Antelo A, Hirama M, Yamashita S, Vieytes MR, Botana LM. Differential effects of ciguatoxin and maitotoxin in primary cultures of cortical neurons. Chemical Research in Toxicology. 27: 1387-400. PMID 24999537 DOI: 10.1021/tx5000969  1
2014 Botana LM, Alfonso A, Vale C, Vilariño N, Rubiolo J, Alonso E, Cagide E. The mechanistic complexities of phycotoxins: Toxicology of Azaspiracids and Yessotoxins Advances in Molecular Toxicology. 8: 1-33. DOI: 10.1016/B978-0-444-63406-1.00001-5  1
2013 Alonso E, Vale C, Vieytes MR, Botana LM. Translocation of PKC by yessotoxin in an in vitro model of Alzheimer's disease with improvement of tau and β-amyloid pathology. Acs Chemical Neuroscience. 4: 1062-70. PMID 23527608 DOI: 10.1021/cn400018y  1
2013 Martín V, Vale C, Bondu S, Thomas OP, Vieytes MR, Botana LM. Differential effects of crambescins and crambescidin 816 in voltage-gated sodium, potassium and calcium channels in neurons. Chemical Research in Toxicology. 26: 169-78. PMID 23270282 DOI: 10.1021/tx3004483  1
2013 Alonso E, Otero P, Vale C, Alfonso A, Antelo A, Giménez-Llort L, Chabaud L, Guillou C, Botana LM. Benefit of 13-desmethyl spirolide C treatment in triple transgenic mouse model of Alzheimer disease: beta-amyloid and neuronal markers improvement. Current Alzheimer Research. 10: 279-89. PMID 23036025 DOI: 10.2174/1567205011310030007  1
2012 Pérez S, Vale C, Alonso E, Fuwa H, Sasaki M, Konno Y, Goto T, Suga Y, Vieytes MR, Botana LM. Effect of gambierol and its tetracyclic and heptacyclic analogues in cultured cerebellar neurons: a structure-activity relationships study. Chemical Research in Toxicology. 25: 1929-37. PMID 22894724 DOI: 10.1021/tx300242m  1
2012 Alonso E, Fuwa H, Vale C, Suga Y, Goto T, Konno Y, Sasaki M, LaFerla FM, Vieytes MR, Giménez-Llort L, Botana LM. Design and synthesis of skeletal analogues of gambierol: attenuation of amyloid-β and tau pathology with voltage-gated potassium channel and N-methyl-D-aspartate receptor implications. Journal of the American Chemical Society. 134: 7467-79. PMID 22475455 DOI: 10.1021/ja300565t  1
2012 Bondu S, Genta-Jouve G, Leiròs M, Vale C, Guigonis JM, Botana LM, Thomas OP. Additional bioactive guanidine alkaloids from the Mediterranean sponge Crambe crambe Rsc Advances. 2: 2828-2835. DOI: 10.1039/c2ra00045h  1
2011 Alonso E, Vale C, Vieytes MR, Laferla FM, Giménez-Llort L, Botana LM. 13-Desmethyl spirolide-C is neuroprotective and reduces intracellular Aβ and hyperphosphorylated tau in vitro. Neurochemistry International. 59: 1056-65. PMID 21907746 DOI: 10.1016/j.neuint.2011.08.013  1
2011 Alonso E, Vale C, Vieytes MR, Laferla FM, Giménez-Llort L, Botana LM. The cholinergic antagonist gymnodimine improves Aβ and tau neuropathology in an in vitro model of Alzheimer disease. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 27: 783-94. PMID 21691095 DOI: 10.1159/000330086  1
2011 Perez S, Vale C, Botana AM, Alonso E, Vieytes MR, Botana LM. Determination of toxicity equivalent factors for paralytic shellfish toxins by electrophysiological measurements in cultured neurons. Chemical Research in Toxicology. 24: 1153-7. PMID 21619049 DOI: 10.1021/tx200173d  1
2011 Pérez S, Vale C, Alonso E, Alfonso C, Rodríguez P, Otero P, Alfonso A, Vale P, Hirama M, Vieytes MR, Botana LM. A comparative study of the effect of ciguatoxins on voltage-dependent Na+ and K+ channels in cerebellar neurons. Chemical Research in Toxicology. 24: 587-96. PMID 21351754 DOI: 10.1021/tx200043j  1
2011 Coelho LS, Felicio LP, Miranda CT, da Silva EM, Vale CR, Lima DC, Duarte SR, Ferreira HD, Chen Chen L, Carvalho S. Modulatory effects of Duguetia furfuracea (A. St. Hil) Benth. and Hook. f. in Drosophila melanogaster somatic and germinative cells. Genetics and Molecular Research : Gmr. 10: 75-85. PMID 21264818 DOI: 10.4238/vol10-1gmr983  1
2011 Felício LP, Silva EM, Ribeiro V, Miranda CT, Vieira IL, Passos DC, Ferreira AK, Vale CR, Lima DC, Carvalho S, Nunes WB. Mutagenic potential and modulatory effects of the medicinal plant Luehea divaricata (Malvaceae) in somatic cells of Drosophila melanogaster: SMART/wing. Genetics and Molecular Research : Gmr. 10: 16-24. PMID 21218382 DOI: 10.4238/vol10-1gmr982  1
2010 Passos DC, Ferreira HD, Vieira IL, Nunes WB, Felício LP, Silva EM, Vale CR, Duarte SR, Silva ES, Carvalho S. Modulatory effect of Palicourea coriacea (Rubiaceae) against damage induced by doxorubicin in somatic cells of Drosophila melanogaster. Genetics and Molecular Research : Gmr. 9: 1153-62. PMID 20568060 DOI: 10.4238/vol9-2gmr801  1
2010 Otero P, Pérez S, Alfonso A, Vale C, Rodríguez P, Gouveia NN, Gouveia N, Delgado J, Vale P, Hirama M, Ishihara Y, Molgó J, Botana LM. First toxin profile of ciguateric fish in Madeira Arquipelago (Europe). Analytical Chemistry. 82: 6032-9. PMID 20557036 DOI: 10.1021/ac100516q  1
2010 Alonso E, Vale C, Sasaki M, Fuwa H, Konno Y, Perez S, Vieytes MR, Botana LM. Calcium oscillations induced by gambierol in cerebellar granule cells. Journal of Cellular Biochemistry. 110: 497-508. PMID 20336695 DOI: 10.1002/jcb.22566  1
2010 Vale C, Alonso E, Rubiolo JA, Vieytes MR, LaFerla FM, Giménez-Llort L, Botana LM. Profile for amyloid-beta and tau expression in primary cortical cultures from 3xTg-AD mice. Cellular and Molecular Neurobiology. 30: 577-90. PMID 19943189 DOI: 10.1007/s10571-009-9482-3  1
2010 Vale C, Nicolaou KC, Frederick MO, Vieytes MR, Botana LM. Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons. Toxicological Sciences : An Official Journal of the Society of Toxicology. 113: 158-68. PMID 19815690 DOI: 10.1093/toxsci/kfp246  1
2010 Vale C, Botana LM. Response: The complexity of the cellular effects of azaspiracid prevents to highlight only one candidate as the target of the toxin Toxicological Sciences. 115: 611. DOI: 10.1093/toxsci/kfq065  1
2010 Botana LM, Vilariño N, Alfonso A, Vale C, Louzao C, Elliott CT, Campbell K, Botana AM. The problem of toxicity equivalent factors in developing alternative methods to animal bioassays for marine-toxin detection Trac - Trends in Analytical Chemistry. 29: 1316-1325. DOI: 10.1016/j.trac.2010.09.004  1
2009 Botana LM, Alfonso A, Botana A, Vieytes MR, Vale C, Vilariño N, Louzao C. Functional assays for marine toxins as an alternative, high-throughput-screening solution to animal tests Trac - Trends in Analytical Chemistry. 28: 603-611. DOI: 10.1016/j.trac.2009.02.014  1
2008 Alfonso C, Rehmann N, Hess P, Alfonso A, Wandscheer CB, Abuín M, Vale C, Otero P, Vieytes MR, Botana LM. Evaluation of various pH and temperature conditions on the stability of azaspiracids and their importance in preparative isolation and toxicological studies. Analytical Chemistry. 80: 9672-80. PMID 19072271 DOI: 10.1021/ac801506d  1
2008 Vale C, Botana LM. Marine toxins and the cytoskeleton: okadaic acid and dinophysistoxins. The Febs Journal. 275: 6060-6. PMID 19016863 DOI: 10.1111/j.1742-4658.2008.06711.x  1
2008 Rodriguez P, Alfonso A, Vale C, Alfonso C, Vale P, Tellez A, Botana LM. First toxicity report of tetrodotoxin and 5,6,11-trideoxyTTX in the trumpet shell Charonia lampas lampas in Europe. Analytical Chemistry. 80: 5622-9. PMID 18558725 DOI: 10.1021/ac800769e  1
2008 Vale C, Wandscheer C, Nicolaou KC, Frederick MO, Alfonso C, Vieytes MR, Botana LM. Cytotoxic effect of azaspiracid-2 and azaspiracid-2-methyl ester in cultured neurons: involvement of the c-Jun N-terminal kinase. Journal of Neuroscience Research. 86: 2952-62. PMID 18500761 DOI: 10.1002/jnr.21731  1
2008 Vale C, Alfonso A, Vieytes MR, Romarís XM, Arévalo F, Botana AM, Botana LM. In vitro and in vivo evaluation of paralytic shellfish poisoning toxin potency and the influence of the pH of extraction. Analytical Chemistry. 80: 1770-6. PMID 18232710 DOI: 10.1021/ac7022266  1
2007 Vale C, Gómez-Limia B, Nicolaou KC, Frederick MO, Vieytes MR, Botana LM. The c-Jun-N-terminal kinase is involved in the neurotoxic effect of azaspiracid-1. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 20: 957-66. PMID 17982278 DOI: 10.1159/000110456  1
2007 Vale C, Gómez-Limia B, Vieytes MR, Botana LM. Mitogen-activated protein kinases regulate palytoxin-induced calcium influx and cytotoxicity in cultured neurons. British Journal of Pharmacology. 152: 256-66. PMID 17641674 DOI: 10.1038/sj.bjp.0707389  1
2007 Martinez-Galan JR, Caminos E, Vale C, Juiz JM. Auditory nerve input is not an absolute requirement for the expression, distribution and calcium permeability of AMPA receptors in the adult rat ventral cochlear nucleus. Brain Research. 1138: 21-9. PMID 17276419 DOI: 10.1016/j.brainres.2006.12.015  1
2007 Vale C, Nicolaou KC, Frederick MO, Gómez-Limia B, Alfonso A, Vieytes MR, Botana LM. Effects of azaspiracid-1, a potent cytotoxic agent, on primary neuronal cultures. A structure-activity relationship study. Journal of Medicinal Chemistry. 50: 356-63. PMID 17228878 DOI: 10.1021/jm061063g  1
2007 Vale C, Ares IR. Biochemistry of Palytoxins and Ostreocins Phycotoxins: Chemistry and Biochemistry. 95-118. DOI: 10.1002/9780470277874.ch6  1
2007 Suñol C, Babot Z, García DA, Vale C. The neuronal GABAA receptor as target for therapeutic and toxic chemical compounds. in vitro studies using cultured cortical neurons Afinidad. 64: 372-377.  1
2006 Vale C, Alfonso A, Suñol C, Vieytes MR, Botana LM. Modulation of calcium entry and glutamate release in cultured cerebellar granule cells by palytoxin. Journal of Neuroscience Research. 83: 1393-406. PMID 16547972 DOI: 10.1002/jnr.20841  1
2006 García DA, Bujons J, Vale C, Suñol C. Allosteric positive interaction of thymol with the GABAA receptor in primary cultures of mouse cortical neurons. Neuropharmacology. 50: 25-35. PMID 16185724 DOI: 10.1016/j.neuropharm.2005.07.009  1
2005 Caminos E, Vale C, Lujan R, Martinez-Galan JR, Juiz JM. Developmental regulation and adult maintenance of potassium channel proteins (Kv 1.1 and Kv 1.2) in the cochlear nucleus of the rat. Brain Research. 1056: 118-31. PMID 16122713 DOI: 10.1016/j.brainres.2005.07.031  1
2005 Vale C, Caminos E, Martinez-Galán JR, Juiz JM. Expression and developmental regulation of the K+-Cl- cotransporter KCC2 in the cochlear nucleus. Hearing Research. 206: 107-15. PMID 16081002 DOI: 10.1016/j.heares.2005.03.012  1
2004 Vale C, Juíz JM, Moore DR, Sanes DH. Unilateral cochlear ablation produces greater loss of inhibition in the contralateral inferior colliculus. The European Journal of Neuroscience. 20: 2133-40. PMID 15450092 DOI: 10.1111/j.1460-9568.2004.03679.x  1
2003 Vale C, Schoorlemmer J, Sanes DH. Deafness disrupts chloride transporter function and inhibitory synaptic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7516-24. PMID 12930790  1
2003 Vale C, Fonfría E, Bujons J, Messeguer A, Rodríguez-Farré E, Suñol C. The organochlorine pesticides gamma-hexachlorocyclohexane (lindane), alpha-endosulfan and dieldrin differentially interact with GABA(A) and glycine-gated chloride channels in primary cultures of cerebellar granule cells. Neuroscience. 117: 397-403. PMID 12614680 DOI: 10.1016/S0306-4522(02)00875-8  1
2002 Vale C, Sanes DH. The effect of bilateral deafness on excitatory and inhibitory synaptic strength in the inferior colliculus. The European Journal of Neuroscience. 16: 2394-404. PMID 12492434 DOI: 10.1046/j.1460-9568.2002.02302.x  1
2000 Vale C, Sanes DH. Afferent regulation of inhibitory synaptic transmission in the developing auditory midbrain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 1912-21. PMID 10684892  1
1999 Vale C, Vilaró MT, Rodríguez-Farré E, Suñol C. Effects of the conformationally restricted GABA analogues, cis- and trans-4-aminocrotonic acid, on GABA neurotransmission in primary neuronal cultures. Journal of Neuroscience Research. 57: 95-105. PMID 10397639 DOI: 10.1002/(SICI)1097-4547(19990701)57:1<95::AID-JNR10>3.0.CO;2-N  1
1998 Suñol C, Vale C, Rodríguez-Farré E. Polychlorocycloalkane insecticide action on GABA-and glycine-dependent chloride flux. Neurotoxicology. 19: 573-80. PMID 9745914  1
1998 Vale C, Damgaard I, Suñol C, Rodríguez-Farré E, Schousboe A. Cytotoxic action of lindane in cerebellar granule neurons is mediated by interaction with inducible GABA(B) receptors. Journal of Neuroscience Research. 52: 286-94. PMID 9590437 DOI: 10.1002/(SICI)1097-4547(19980501)52:3<286::AID-JNR5>3.0.CO;2-9  1
1998 Vale C, Damgaard I, Suñol C, Rodríguez-Farré E, Schousboe A. Cytotoxic action of lindane in neocortical GABAergic neurons is primarily mediated by interaction with flunitrazepam-sensitive GABA(A) receptors. Journal of Neuroscience Research. 52: 276-85. PMID 9590436 DOI: 10.1002/(SICI)1097-4547(19980501)52:3<276::AID-JNR4>3.0.CO;2-A  1
1998 Suñol C, Vale C. γ-Aminobutyric acid (GABA) and glutamate neurotransmission during epileptiform activity in in vitro neural models Expert Opinion On Therapeutic Targets. 2: 53-56. DOI: 10.1517/14728222.2.1.53  1
1997 Vale C, Pomés A, Rodríguez-Farré E, Suñol C. Allosteric interactions between gamma-aminobutyric acid, benzodiazepine and picrotoxinin binding sites in primary cultures of cerebellar granule cells. Differential effects induced by gamma- and delta-hexachlorocyclohexane. European Journal of Pharmacology. 319: 343-53. PMID 9042610 DOI: 10.1016/S0014-2999(96)00866-7  1
Show low-probability matches.