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Jeffery S. Tessem, Ph.D. - Publications

Affiliations: 
2000-2007 Biochemistry and Molecular Biology University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
 2007-2013 Sarah W. Stedman Center for Nutrition and Metabolism Duke Medical School, Durham, NC, United States 
Area:
Molecular Biology, Immunology
Website:
tessemlab.byu.edu
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Krueger ES, Griffin LE, Beales JL, Lloyd TS, Brown NJ, Elison WS, Kay CD, Neilson AP, Tessem JS. Bioavailable Microbial Metabolites of Flavanols Demonstrate Highly Individualized Bioactivity on In Vitro β-Cell Functions Critical for Metabolic Health. Metabolites. 13. PMID 37512508 DOI: 10.3390/metabo13070801  0.8
2022 Racine KC, Iglesias-Carres L, Herring JA, Ferruzzi MG, Kay CD, Tessem JS, Neilson AP. Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study. Biochemical and Biophysical Research Communications. 626: 205-210. PMID 35994831 DOI: 10.1016/j.bbrc.2022.08.018  0.748
2022 Allen JG, Tessem JS. Ca Sensors Assemble: Function of the MCU Complex in the Pancreatic Beta Cell. Cells. 11. PMID 35805078 DOI: 10.3390/cells11131993  0.321
2022 Iglesias-Carres L, Krueger ES, Herring JA, Tessem JS, Neilson AP. Potential of Phenolic Compounds and Their Gut Microbiota-Derived Metabolites to Reduce TMA Formation: Application of an Fermentation High-Throughput Screening Model. Journal of Agricultural and Food Chemistry. PMID 35235743 DOI: 10.1021/acs.jafc.2c00247  0.728
2021 Krueger ES, Beales JL, Russon KB, Elison WS, Davis JR, Hansen JM, Neilson AP, Hansen JM, Tessem JS. Gut Metabolite Trimethylamine N-Oxide Protects INS-1 β-Cell and Rat Islet Function under Diabetic Glucolipotoxic Conditions. Biomolecules. 11. PMID 34944536 DOI: 10.3390/biom11121892  0.829
2021 Aitken TJ, Crabtree JE, Jensen DM, Hess KH, Leininger BR, Tessem JS. Decreased proliferation of aged rat beta cells corresponds with enhanced expression of the cell cycle inhibitor p27. Biology of the Cell. PMID 34523154 DOI: 10.1111/boc.202100035  0.701
2021 Simonett SP, Shin S, Herring JA, Bacher R, Smith LA, Dong C, Rabaglia ME, Stapleton DS, Schueler KL, Choi J, Bernstein MN, Turkewitz DR, Perez-Cervantes C, Spaeth J, Stein R, ... Tessem JS, et al. Identification of direct transcriptional targets of NFATC2 that promote β-cell proliferation. The Journal of Clinical Investigation. PMID 34491912 DOI: 10.1172/JCI144833  0.786
2021 Krueger ES, Lloyd TS, Tessem JS. The Accumulation and Molecular Effects of Trimethylamine N-Oxide on Metabolic Tissues: It's Not All Bad. Nutrients. 13. PMID 34445033 DOI: 10.3390/nu13082873  0.774
2020 Jensen DM, Hendricks KV, Mason AT, Tessem JS. Good Cop, Bad Cop: The Opposing Effects of Macrophage Activation State on Maintaining or Damaging Functional β-Cell Mass. Metabolites. 10. PMID 33256225 DOI: 10.3390/metabo10120485  0.343
2020 Chen T, Hill JT, Moore TM, Cheung ECK, Olsen ZE, Piorczynski TB, Marriott TD, Tessem JS, Walton CM, Bikman BT, Hansen JM, Thomson DM. Lack of skeletal muscle liver kinase B1 alters gene expression, mitochondrial content, inflammation and oxidative stress without affecting high-fat diet-induced obesity or insulin resistance. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165805. PMID 32339642 DOI: 10.1016/J.Bbadis.2020.165805  0.358
2020 DELEYE Y, HERRING J, HESS KH, LEININGER B, MCGARRAH RW, TESSEM JS, WHITE PJ. 2120-P: The Protein Phosphatase M1K Connects Glucose Sensing to Protein Translation in Pancreatic Beta Cells Diabetes. 69: 2120-P. DOI: 10.2337/Db20-2120-P  0.759
2020 Yang H, Herring J, Wynn A, Elison W, Walton C, Good L, Marchant E, Marchant N, Bikman B, Tessem JS. Full body loss of the nuclear hormone receptor Nr4a3 results induces obesity and glucose intolerance. The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05965  0.752
2020 Krueger E, Austin M, Ekpo I, Beales J, Yang H, Nielson A, Tessem JS. Screening Phytochemicals for Alternative Diabetes Treatments The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05911  0.751
2020 Crabtree J, Littlefield C, Tessem JS. Why Does Nkx6.1 Fail to Increase Functional Beta‐cell Mass in Aged Islets? The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05831  0.606
2020 Lloyd T, Griffin L, Krueger E, Beales J, Barlow A, Sheets J, Ekpo I, Ross M, Chandra P, Rathore A, Kay C, Neilson A, Tessem JS. Supplemental treatment options for diabetes: how flavanol metabolites improve β‐cell function The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05762  0.762
2019 Herring JA, Elison WS, Tessem JS. Function of Nr4a Orphan Nuclear Receptors in Proliferation, Apoptosis and Fuel Utilization Across Tissues. Cells. 8. PMID 31683815 DOI: 10.3390/Cells8111373  0.745
2019 DELEYE Y, HERRING J, HESS KH, LEININGER BR, HANNOU SA, ASTAPOVA I, HERMAN MA, TESSEM JS, WHITE PJ. 2191-P: PPM1K Regulates ß-Cell Proliferation, Insulin Content, and GSIS Diabetes. 68: 2191-P. DOI: 10.2337/DB19-2191-P  0.776
2019 TESSEM JS, HERRING J, SMITH CJ, AUSTIN MC, WYNN AG. 2190-P: Sex-Based Differences in Nr4a1 Beta-Cell Activity Diabetes. 68: 2190-P. DOI: 10.2337/Db19-2190-P  0.792
2019 Herring JA, Smith CJ, Kener KB, Wynn AG, Austin MC, Tessem JS. Gender specific effects of Nr4a1 on functional β‐cell mass The Faseb Journal. 33. DOI: 10.1096/Fasebj.2019.33.1_Supplement.487.7  0.742
2018 Draney C, Austin MC, Leifer AH, Smith CJ, Kener KB, Aitken TJ, Hess KH, Haines AC, Lett LA, Hernandez-Carretero A, Fueger PT, Arlotto M, Tessem JS. HDAC1 Overexpression Enhances β-cell proliferation by Downregulating Cdkn1b/p27. The Biochemical Journal. PMID 30322885 DOI: 10.1042/Bcj20180465  0.808
2018 Bitner BF, Ray JD, Kener KB, Herring JA, Tueller JA, Johnson DK, Tellez Freitas CM, Fausnacht DW, Allen ME, Thomson AH, Weber KS, McMillan RP, Hulver MW, Brown DA, Tessem JS, et al. Common gut microbial metabolites of dietary flavonoids exert potent protective activities in β-cells and skeletal muscle cells. The Journal of Nutritional Biochemistry. 62: 95-107. PMID 30286378 DOI: 10.1016/J.Jnutbio.2018.09.004  0.819
2018 Parker BA, Walton CM, Carr ST, Andrus JL, Cheung ECK, Duplisea MJ, Wilson EK, Draney C, Lathen DR, Kenner KB, Thomson DM, Tessem JS, Bikman BT. β-Hydroxybutyrate Elicits Favorable Mitochondrial Changes in Skeletal Muscle. International Journal of Molecular Sciences. 19. PMID 30071599 DOI: 10.3390/Ijms19082247  0.771
2018 Kener KB, Munk DJ, Hancock CR, Tessem JS. High-resolution Respirometry to Measure Mitochondrial Function of Intact Beta Cells in the Presence of Natural Compounds. Journal of Visualized Experiments : Jove. PMID 29443067 DOI: 10.3791/57053  0.425
2018 SMITH CJ, KENER KB, TESSEM JS. Nr4a1 and Nr4a3 Knock Out Mice Have Impaired Glucose Clearance and Beta-Cell Function under High-Fat Feeding Diabetes. 67: 2040-P. DOI: 10.2337/Db18-2040-P  0.398
2017 Rowley TJ, Bitner BF, Ray JD, Lathen DR, Smithson AT, Dallon BW, Plowman CJ, Bikman BT, Hansen JM, Dorenkott MR, Goodrich KM, Ye L, O'Keefe SF, Neilson AP, Tessem JS. Monomeric cocoa catechins enhance β-cell function by increasing mitochondrial respiration. The Journal of Nutritional Biochemistry. 49: 30-41. PMID 28863367 DOI: 10.1016/J.Jnutbio.2017.07.015  0.827
2017 Banks CJ, Rodriguez NW, Gashler KR, Pandya R, Mortenson JB, Whited MD, Soderblom EJ, Thompson JW, Moseley MA, Reddi AR, Tessem JS, Torres MP, Bikman BT, Andersen JL. Acylation of Superoxide Dismutase 1 (SOD1) at K122 Governs SOD1-mediated Inhibition of Mitochondrial Respiration. Molecular and Cellular Biology. PMID 28739857 DOI: 10.1128/Mcb.00354-17  0.313
2017 Sampson M, Lathen DR, Dallon BW, Draney C, Ray JD, Kener KB, Parker BA, Gibbs JL, Gropp JS, Tessem JS, Bikman BT. β-Hydroxybutyrate improves β-cell mitochondrial function and survival Journal of Insulin Resistance. 1. DOI: 10.4102/JIR.V2I1.25  0.818
2016 Strat KM, Rowley TJ, Smithson AT, Tessem JS, Hulver MW, Liu D, Davy BM, Davy KP, Neilson AP. Mechanisms by which cocoa flavanols improve metabolic syndrome and related disorders. The Journal of Nutritional Biochemistry. 35: 1-21. PMID 27560446 DOI: 10.1016/J.Jnutbio.2015.12.008  0.769
2016 Reynolds MS, Hancock CR, Ray JD, Kener KB, Draney C, Garland K, Hardman J, Bikman BT, Tessem JS. β-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00022.2016. PMID 27221116 DOI: 10.1152/Ajpendo.00022.2016  0.805
2016 Ray JD, Kener KB, Bitner BF, Wright B, Ballard M, Barrett EJ, Hill JT, Moss LG, Tessem JS. Nkx6.1-mediated insulin secretion and β-cell proliferation is dependent on upregulation of c-Fos. Febs Letters. PMID 27164028 DOI: 10.1002/1873-3468.12208  0.511
2016 Draney C, Hobson AE, Grover SG, Jack BO, Tessem JS. Cdk5r1 Overexpression Induces Primary β-Cell Proliferation. Journal of Diabetes Research. 2016: 6375804. PMID 26788519 DOI: 10.1155/2016/6375804  0.812
2015 Hobson A, Draney C, Stratford A, Becker TC, Lu D, Arlotto M, Tessem JS. Aurora Kinase A is critical for the Nkx6.1 mediated β-cell proliferation pathway. Islets. 7: e1027854. PMID 26030060 DOI: 10.1080/19382014.2015.1027854  0.803
2014 Tessem JS, Moss LG, Chao LC, Arlotto M, Lu D, Jensen MV, Stephens SB, Tontonoz P, Hohmeier HE, Newgard CB. Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors. Proceedings of the National Academy of Sciences of the United States of America. 111: 5242-7. PMID 24706823 DOI: 10.1073/Pnas.1320953111  0.658
2008 Tessem JS, Jensen JN, Pelli H, Dai XM, Zong XH, Stanley ER, Jensen J, DeGregori J. Critical roles for macrophages in islet angiogenesis and maintenance during pancreatic degeneration. Diabetes. 57: 1605-17. PMID 18375440 DOI: 10.2337/Db07-1577  0.601
2008 Schisler JC, Fueger PT, Babu DA, Hohmeier HE, Tessem JS, Lu D, Becker TC, Naziruddin B, Levy M, Mirmira RG, Newgard CB. Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1. Molecular and Cellular Biology. 28: 3465-76. PMID 18347054 DOI: 10.1128/Mcb.01791-07  0.59
2007 Tessem JS, Pelli H, Dai X, Zong X, Stanley ER, Jensen J, Jensen JN, DeGregori J. A CRITICAL ROLE FOR MACROPHAGES IN PREVENTING PANCREATITIS ASSOCIATED DIABETES Pancreas. 35: 431. DOI: 10.1097/01.Mpa.0000297798.65422.79  0.556
2004 Tessem JS, DeGregori J. Roles for bone-marrow-derived cells in beta-cell maintenance. Trends in Molecular Medicine. 10: 558-64. PMID 15519282 DOI: 10.1016/J.Molmed.2004.09.002  0.579
2003 Li FX, Zhu JW, Tessem JS, Beilke J, Varella-Garcia M, Jensen J, Hogan CJ, DeGregori J. The development of diabetes in E2f1/E2f2 mutant mice reveals important roles for bone marrow-derived cells in preventing islet cell loss. Proceedings of the National Academy of Sciences of the United States of America. 100: 12935-40. PMID 14566047 DOI: 10.1073/Pnas.2231861100  0.608
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