Year |
Citation |
Score |
2023 |
Talvio K, Wagner VA, Minkeviciene R, Kirkwood JS, Kulinich AO, Umemori J, Bhatia A, Hur M, Käkelä R, Ethell IM, Castrén ML. An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis. Communications Biology. 6: 789. PMID 37516746 DOI: 10.1038/s42003-023-05147-9 |
0.738 |
|
2022 |
Dennys C, Baggio C, Rodrigo R, Roussel F, Kulinich A, Heintzman S, Fox A, Kolb SJ, Shaw PJ, Ethell IM, Pellecchia M, Meyer KC. EphA4 targeting agents protect motor neurons from cell death induced by amyotrophic lateral sclerosis -astrocytes. Iscience. 25: 104877. PMID 36034213 DOI: 10.1016/j.isci.2022.104877 |
0.739 |
|
2021 |
Rais M, Lovelace JW, Shuai XS, Woodard W, Bishay S, Estrada L, Sharma AR, Nguy A, Kulinich A, Pirbhoy PS, Palacios AR, Nelson DL, Razak KA, Ethell IM. Functional consequences of postnatal interventions in a mouse model of Fragile X syndrome. Neurobiology of Disease. 162: 105577. PMID 34871737 DOI: 10.1016/j.nbd.2021.105577 |
0.786 |
|
2021 |
Razak KA, Binder DK, Ethell IM. Neural Correlates of Auditory Hypersensitivity in Fragile X Syndrome. Frontiers in Psychiatry. 12: 720752. PMID 34690832 DOI: 10.3389/fpsyt.2021.720752 |
0.744 |
|
2021 |
Pirbhoy PS, Jonak CR, Syed R, Argueta DA, Perez PA, Wiley MB, Hessamian K, Lovelace JW, Razak KA, DiPatrizio NV, Ethell IM, Binder DK. Increased 2-arachidonoyl-sn-glycerol levels normalize cortical responses to sound and improve behaviors in Fmr1 KO mice. Journal of Neurodevelopmental Disorders. 13: 47. PMID 34645383 DOI: 10.1186/s11689-021-09394-x |
0.813 |
|
2021 |
Peteri UK, Pitkonen J, de Toma I, Nieminen O, Utami KH, Strandin TM, Corcoran P, Roybon L, Vaheri A, Ethell I, Casarotto P, Pouladi MA, Castrén ML. Urokinase plasminogen activator mediates changes in human astrocytes modeling fragile X syndrome. Glia. PMID 34427356 DOI: 10.1002/glia.24080 |
0.306 |
|
2021 |
Baggio C, Kulinich A, Dennys CN, Rodrigo R, Meyer K, Ethell I, Pellecchia M. NMR-Guided Design of Potent and Selective EphA4 Agonistic Ligands. Journal of Medicinal Chemistry. PMID 34293864 DOI: 10.1021/acs.jmedchem.1c00608 |
0.729 |
|
2020 |
Lovelace JW, Ethell IM, Binder DK, Razak KA. Minocycline Treatment Reverses Sound Evoked EEG Abnormalities in a Mouse Model of Fragile X Syndrome. Frontiers in Neuroscience. 14: 771. PMID 32848552 DOI: 10.3389/Fnins.2020.00771 |
0.735 |
|
2020 |
Nguyen AQ, Sutley S, Koeppen J, Mina K, Woodruff S, Hanna S, Vengala A, Hickmott PW, Obenaus A, Ethell IM. Astrocytic Ephrin-B1 Controls Excitatory-Inhibitory Balance in Developing Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 40: 6854-6871. PMID 32801156 DOI: 10.1523/Jneurosci.0413-20.2020 |
0.806 |
|
2020 |
Pirbhoy PS, Rais M, Lovelace JW, Woodard W, Razak KA, Binder DK, Ethell IM. Acute pharmacological inhibition of matrix metalloproteinase-9 activity during development restores perineuronal net formation and normalizes auditory processing in Fmr1 KO mice. Journal of Neurochemistry. PMID 32374912 DOI: 10.1111/Jnc.15037 |
0.807 |
|
2020 |
Nguyen AO, Binder DK, Ethell IM, Razak KA. Abnormal development of auditory responses in the inferior colliculus of a mouse model of Fragile X Syndrome. Journal of Neurophysiology. PMID 32319849 DOI: 10.1152/Jn.00706.2019 |
0.76 |
|
2020 |
Nguyen AQ, Koeppen J, Woodruff S, Mina K, Figueroa Z, Ethell IM. Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory. Frontiers in Synaptic Neuroscience. 12: 10. PMID 32256333 DOI: 10.3389/Fnsyn.2020.00010 |
0.785 |
|
2020 |
Jonak CR, Lovelace JW, Ethell IM, Razak KA, Binder DK. Multielectrode array analysis of EEG biomarkers in a mouse model of Fragile X Syndrome. Neurobiology of Disease. 104794. PMID 32036032 DOI: 10.1016/J.Nbd.2020.104794 |
0.722 |
|
2019 |
Kulinich AO, Reinhard SM, Rais M, Lovelace JW, Scott V, Binder DK, Razak KA, Ethell IM. Beneficial effects of sound exposure on auditory cortex development in a mouse model of Fragile X Syndrome. Neurobiology of Disease. 104622. PMID 31698054 DOI: 10.1016/J.Nbd.2019.104622 |
0.802 |
|
2019 |
Lovelace JW, Rais M, Palacios AR, Shuai XS, Bishay S, Popa O, Pirbhoy PS, Binder DK, Nelson DL, Ethell IM, Razak KA. Deletion of Fmr1 from Forebrain Excitatory Neurons Triggers Abnormal Cellular, EEG, and Behavioral Phenotypes in the Auditory Cortex of a Mouse Model of Fragile X Syndrome. Cerebral Cortex (New York, N.Y. : 1991). PMID 31364704 DOI: 10.1093/Cercor/Bhz141 |
0.822 |
|
2019 |
Reinhard SM, Rais M, Afroz S, Hanania Y, Pendi K, Espinoza K, Rosenthal R, Binder DK, Ethell IM, Razak KA. Reduced perineuronal net expression in Fmr1 KO mice auditory cortex and amygdala is linked to impaired fear -associated memory. Neurobiology of Learning and Memory. 107042. PMID 31326533 DOI: 10.1016/J.Nlm.2019.107042 |
0.808 |
|
2019 |
Toledo MA, Wen TH, Binder DK, Ethell IM, Razak KA. Reversal of ultrasonic vocalization deficits in a mouse model of Fragile X Syndrome with minocycline treatment or genetic reduction of MMP-9. Behavioural Brain Research. 372: 112068. PMID 31271818 DOI: 10.1016/J.Bbr.2019.112068 |
0.813 |
|
2019 |
Kokash J, Alderson EM, Reinhard SM, Crawford CA, Binder DK, Ethell IM, Razak KA. Genetic reduction of MMP-9 in the Fmr1 KO mouse partially rescues prepulse inhibition of acoustic startle response. Brain Research. PMID 31128097 DOI: 10.1016/J.Brainres.2019.05.029 |
0.755 |
|
2018 |
Wen TH, Lovelace JW, Ethell IM, Binder DK, Razak KA. Developmental Changes in EEG Phenotypes in a Mouse Model of Fragile X Syndrome. Neuroscience. PMID 30528856 DOI: 10.1016/J.Neuroscience.2018.11.047 |
0.809 |
|
2018 |
Jonak CR, Lovelace JW, Ethell IM, Razak KA, Binder DK. Reusable Multielectrode Array Technique for Electroencephalography in Awake Freely Moving Mice. Frontiers in Integrative Neuroscience. 12: 53. PMID 30416434 DOI: 10.3389/Fnint.2018.00053 |
0.691 |
|
2018 |
Rais M, Binder DK, Razak KA, Ethell IM. Sensory Processing Phenotypes in Fragile X Syndrome. Asn Neuro. 10: 1759091418801092. PMID 30231625 DOI: 10.1177/1759091418801092 |
0.806 |
|
2018 |
Wen TH, Binder DK, Ethell IM, Razak KA. The Perineuronal 'Safety' Net? Perineuronal Net Abnormalities in Neurological Disorders. Frontiers in Molecular Neuroscience. 11: 270. PMID 30123106 DOI: 10.3389/Fnmol.2018.00270 |
0.809 |
|
2018 |
Koeppen J, Nguyen AQ, Nikolakopoulou AM, Garcia M, Hanna S, Woodruff S, Figueroa Z, Obenaus A, Ethell IM. Functional consequences of synapse remodeling following astrocyte-specific regulation of ephrin-B1 in the adult hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29793972 DOI: 10.1523/Jneurosci.3618-17.2018 |
0.798 |
|
2018 |
Lovelace JW, Ethell IM, Binder DK, Razak KA. Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome. Neurobiology of Disease. PMID 29605426 DOI: 10.1016/J.Nbd.2018.03.012 |
0.748 |
|
2017 |
Wen TH, Afroz S, Reinhard SM, Palacios AR, Tapia K, Binder DK, Razak KA, Ethell IM. Genetic Reduction of Matrix Metalloproteinase-9 Promotes Formation of Perineuronal Nets Around Parvalbumin-Expressing Interneurons and Normalizes Auditory Cortex Responses in Developing Fmr1 Knock-Out Mice. Cerebral Cortex (New York, N.Y. : 1991). 1-14. PMID 29040407 DOI: 10.1093/Cercor/Bhx258 |
0.83 |
|
2017 |
On V, Zahedi A, Ethell IM, Bhanu B. Automated spatio-temporal analysis of dendritic spines and related protein dynamics. Plos One. 12: e0182958. PMID 28827828 DOI: 10.1371/Journal.Pone.0182958 |
0.32 |
|
2017 |
Wu B, De SK, Kulinich A, Salem AF, Koeppen J, Wang R, Barile E, Wang S, Zhang D, Ethell I, Pellecchia M. Potent and Selective EphA4 Agonists for the Treatment of ALS. Cell Chemical Biology. PMID 28196613 DOI: 10.1016/J.Chembiol.2017.01.006 |
0.76 |
|
2016 |
David CN, Frias ES, Szu JI, Vieira PA, Hubbard JA, Lovelace J, Michael M, Worth D, McGovern KE, Ethell IM, Stanley BG, Korzus E, Fiacco TA, Binder DK, Wilson EH. GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii. Plos Pathogens. 12: e1005643. PMID 27281462 DOI: 10.1371/Journal.Ppat.1005643 |
0.579 |
|
2016 |
Nikolakopoulou AM, Koeppen J, Garcia M, Leish J, Obenaus A, Ethell IM. Astrocytic Ephrin-B1 Regulates Synapse Remodeling Following Traumatic Brain Injury. Asn Neuro. 8. PMID 26928051 DOI: 10.1177/1759091416630220 |
0.791 |
|
2016 |
Lovelace JW, Wen TH, Reinhard S, Hsu MS, Sidhu H, Ethell IM, Binder DK, Razak KA. Matrix metalloproteinase-9 deletion rescues auditory evoked potential habituation deficit in a mouse model of Fragile X Syndrome. Neurobiology of Disease. PMID 26850918 DOI: 10.1016/J.Nbd.2016.02.002 |
0.822 |
|
2015 |
Reinhard SM, Razak K, Ethell IM. A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders. Frontiers in Cellular Neuroscience. 9: 280. PMID 26283917 DOI: 10.3389/Fncel.2015.00280 |
0.643 |
|
2014 |
Sidhu H, Dansie LE, Hickmott PW, Ethell DW, Ethell IM. Genetic removal of matrix metalloproteinase 9 rescues the symptoms of fragile X syndrome in a mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9867-79. PMID 25057190 DOI: 10.1523/Jneurosci.1162-14.2014 |
0.812 |
|
2013 |
Dansie LE, Phommahaxay K, Okusanya AG, Uwadia J, Huang M, Rotschafer SE, Razak KA, Ethell DW, Ethell IM. Long-lasting effects of minocycline on behavior in young but not adult Fragile X mice. Neuroscience. 246: 186-98. PMID 23660195 DOI: 10.1016/J.Neuroscience.2013.04.058 |
0.806 |
|
2013 |
Zahedi A, DeFea K, Ethell I. Optogenetics to target actin-mediated synaptic loss in Alzheimer's Proceedings of Spie. 8586. DOI: 10.1117/12.2000480 |
0.352 |
|
2012 |
Pontrello CG, Sun MY, Lin A, Fiacco TA, DeFea KA, Ethell IM. Cofilin under control of β-arrestin-2 in NMDA-dependent dendritic spine plasticity, long-term depression (LTD), and learning. Proceedings of the National Academy of Sciences of the United States of America. 109: E442-51. PMID 22308427 DOI: 10.1073/Pnas.1118803109 |
0.804 |
|
2012 |
Rotschafer SE, Trujillo MS, Dansie LE, Ethell IM, Razak KA. Minocycline treatment reverses ultrasonic vocalization production deficit in a mouse model of Fragile X Syndrome. Brain Research. 1439: 7-14. PMID 22265702 DOI: 10.1016/J.Brainres.2011.12.041 |
0.8 |
|
2012 |
Sloniowski S, Ethell IM. Looking forward to EphB signaling in synapses. Seminars in Cell & Developmental Biology. 23: 75-82. PMID 22040917 DOI: 10.1016/J.Semcdb.2011.10.020 |
0.776 |
|
2011 |
Dansie LE, Ethell IM. Casting a net on dendritic spines: the extracellular matrix and its receptors. Developmental Neurobiology. 71: 956-81. PMID 21834084 DOI: 10.1002/Dneu.20963 |
0.8 |
|
2011 |
Cesa R, Premoselli F, Renna A, Ethell IM, Pasquale EB, Strata P. Eph receptors are involved in the activity-dependent synaptic wiring in the mouse cerebellar cortex. Plos One. 6: e19160. PMID 21559471 DOI: 10.1371/Journal.Pone.0019160 |
0.406 |
|
2010 |
Paribello C, Tao L, Folino A, Berry-Kravis E, Tranfaglia M, Ethell IM, Ethell DW. Open-label add-on treatment trial of minocycline in fragile X syndrome. Bmc Neurology. 10: 91. PMID 20937127 DOI: 10.1186/1471-2377-10-91 |
0.388 |
|
2010 |
Utari A, Chonchaiya W, Rivera SM, Schneider A, Hagerman RJ, Faradz SM, Ethell IM, Nguyen DV. Side effects of minocycline treatment in patients with fragile X syndrome and exploration of outcome measures. American Journal On Intellectual and Developmental Disabilities. 115: 433-43. PMID 20687826 DOI: 10.1352/1944-7558-115.5.433 |
0.33 |
|
2010 |
Yang NY, Lopez-Bergami P, Goydos JS, Yip D, Walker AM, Pasquale EB, Ethell IM. The EphB4 receptor promotes the growth of melanoma cells expressing the ephrin-B2 ligand. Pigment Cell & Melanoma Research. 23: 684-7. PMID 20649938 DOI: 10.1111/J.1755-148X.2010.00745.X |
0.573 |
|
2009 |
Pontrello CG, Ethell IM. Accelerators, Brakes, and Gears of Actin Dynamics in Dendritic Spines. The Open Neuroscience Journal. 3: 67-86. PMID 20463852 DOI: 10.2174/1874082000903020067 |
0.79 |
|
2009 |
Shi Y, Pontrello CG, DeFea KA, Reichardt LF, Ethell IM. Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8129-42. PMID 19553453 DOI: 10.1523/Jneurosci.4681-08.2009 |
0.796 |
|
2009 |
Bilousova TV, Dansie L, Ngo M, Aye J, Charles JR, Ethell DW, Ethell IM. Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model. Journal of Medical Genetics. 46: 94-102. PMID 18835858 DOI: 10.1136/Jmg.2008.061796 |
0.786 |
|
2008 |
Lin KT, Sloniowski S, Ethell DW, Ethell IM. Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion. The Journal of Biological Chemistry. 283: 28969-79. PMID 18713744 DOI: 10.1074/Jbc.M804401200 |
0.782 |
|
2007 |
Carson MJ, Bilousova TV, Puntambekar SS, Melchior B, Doose JM, Ethell IM. A rose by any other name? The potential consequences of microglial heterogeneity during CNS health and disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 4: 571-9. PMID 17920538 DOI: 10.1016/J.Nurt.2007.07.002 |
0.677 |
|
2007 |
Ethell IM, Ethell DW. Matrix metalloproteinases in brain development and remodeling: synaptic functions and targets. Journal of Neuroscience Research. 85: 2813-23. PMID 17387691 DOI: 10.1002/Jnr.21273 |
0.458 |
|
2006 |
Yang NY, Pasquale EB, Owen LB, Ethell IM. The EphB4 receptor-tyrosine kinase promotes the migration of melanoma cells through Rho-mediated actin cytoskeleton reorganization. The Journal of Biological Chemistry. 281: 32574-86. PMID 16950769 DOI: 10.1074/Jbc.M604338200 |
0.602 |
|
2006 |
Bilousova TV, Rusakov DA, Ethell DW, Ethell IM. Matrix metalloproteinase-7 disrupts dendritic spines in hippocampal neurons through NMDA receptor activation. Journal of Neurochemistry. 97: 44-56. PMID 16515559 DOI: 10.1111/J.1471-4159.2006.03701.X |
0.744 |
|
2006 |
Shi Y, Ethell IM. Integrins control dendritic spine plasticity in hippocampal neurons through NMDA receptor and Ca2+/calmodulin-dependent protein kinase II-mediated actin reorganization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1813-22. PMID 16467530 DOI: 10.1523/Jneurosci.4091-05.2006 |
0.514 |
|
2006 |
Hickmott PW, Ethell IM. Dendritic plasticity in the adult neocortex. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 12: 16-28. PMID 16394190 DOI: 10.1177/1073858405282417 |
0.348 |
|
2006 |
Moeller ML, Shi Y, Reichardt LF, Ethell IM. EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activation. The Journal of Biological Chemistry. 281: 1587-98. PMID 16298995 DOI: 10.1074/Jbc.M511756200 |
0.73 |
|
2005 |
Hoogenraad CC, Milstein AD, Ethell IM, Henkemeyer M, Sheng M. GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking. Nature Neuroscience. 8: 906-15. PMID 15965473 DOI: 10.1038/Nn1487 |
0.377 |
|
2005 |
Ethell IM, Pasquale EB. Molecular mechanisms of dendritic spine development and remodeling. Progress in Neurobiology. 75: 161-205. PMID 15882774 DOI: 10.1016/J.Pneurobio.2005.02.003 |
0.346 |
|
2003 |
Henkemeyer M, Itkis OS, Ngo M, Hickmott PW, Ethell IM. Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus. The Journal of Cell Biology. 163: 1313-26. PMID 14691139 DOI: 10.1083/Jcb.200306033 |
0.417 |
|
2001 |
Ethell IM, Irie F, Kalo MS, Couchman JR, Pasquale EB, Yamaguchi Y. EphB/syndecan-2 signaling in dendritic spine morphogenesis. Neuron. 31: 1001-13. PMID 11580899 DOI: 10.1016/S0896-6273(01)00440-8 |
0.365 |
|
2001 |
Miura R, Ethell IM, Yamaguchi Y. Carbohydrate-protein interactions between HNK-1-reactive sulfoglucuronyl glycolipids and the proteoglycan lectin domain mediate neuronal cell adhesion and neurite outgrowth Journal of Neurochemistry. 76: 413-424. PMID 11208904 DOI: 10.1046/J.1471-4159.2001.00042.X |
0.32 |
|
2000 |
Ethell IM, Hagihara K, Miura Y, Irie F, Yamaguchi Y. Synbindin, a novel syndecan-2-binding protein in neuronal dendritic spines Journal of Cell Biology. 151: 53-67. PMID 11018053 DOI: 10.1083/Jcb.151.1.53 |
0.37 |
|
2000 |
Gärtner A, Shostak Y, Hackel N, Ethell IM, Thoenen H. Ultrastructural identification of storage compartments and localization of activity-dependent secretion of neurotrophin 6 in hippocampal neurons. Molecular and Cellular Neurosciences. 15: 215-34. PMID 10736200 DOI: 10.1006/Mcne.1999.0825 |
0.321 |
|
1999 |
Ethell IM, Yamaguchi Y. Cell surface heparan sulfate proteoglycan syndecan-2 induces the maturation of dendritic spines in rat hippocampal neurons Journal of Cell Biology. 144: 575-586. PMID 9971750 DOI: 10.1083/Jcb.144.3.575 |
0.367 |
|
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