Year |
Citation |
Score |
2014 |
Moldthan HL, Hirko AC, Thinschmidt JS, Grant MB, Li Z, Peris J, Lu Y, Elshikha AS, King MA, Hughes JA, Song S. Alpha 1-antitrypsin therapy mitigated ischemic stroke damage in rats. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 23: e355-63. PMID 24582784 DOI: 10.1016/J.Jstrokecerebrovasdis.2013.12.029 |
0.745 |
|
2011 |
Le HT, Hirko AC, Thinschmidt JS, Grant M, Li Z, Peris J, King MA, Hughes JA, Song S. The protective effects of plasma gelsolin on stroke outcome in rats. Experimental & Translational Stroke Medicine. 3: 13. PMID 22047744 DOI: 10.1186/2040-7378-3-13 |
0.75 |
|
2011 |
Niu G, Driessen WH, Sullivan SM, Hughes JA. In vivo anti-tumor effect of expressing p14ARF-TAT using a FGF2-targeted cationic lipid vector. Pharmaceutical Research. 28: 720-30. PMID 21246396 DOI: 10.1007/S11095-010-0353-X |
0.408 |
|
2010 |
Le HT, Rao GA, Hirko AC, Hughes JA. Polymeric nanoparticles containing conjugated phospholipase A2 for nonviral gene delivery. Molecular Pharmaceutics. 7: 1090-7. PMID 20459116 DOI: 10.1021/Mp900192P |
0.798 |
|
2010 |
Niu G, Cogburn B, Hughes J. Preparation and characterization of doxorubicin liposomes. Methods of Molecular Biology. 624: 211-219. PMID 20217598 DOI: 10.1007/978-1-60761-609-2_14 |
0.316 |
|
2010 |
Hughes J, Yadava P, Mesaros R. Liposomal siRNA delivery. Methods in Molecular Biology (Clifton, N.J.). 605: 445-59. PMID 20072900 DOI: 10.1007/978-1-60327-360-2_31 |
0.785 |
|
2008 |
Yadava P, Gibbs M, Castro C, Hughes JA. Effect of lyophilization and freeze-thawing on the stability of siRNA-liposome complexes. Aaps Pharmscitech. 9: 335-41. PMID 18431646 DOI: 10.1208/S12249-007-9000-1 |
0.787 |
|
2008 |
Terrell J, Yadava P, Castro C, Hughes J. Liposome fluidity alters interactions between the ganglioside GM1 and cholera toxin B subunit Journal of Liposome Research. 18: 21-29. PMID 18348069 DOI: 10.1080/08982100801893929 |
0.763 |
|
2008 |
Rao GA, Tsai R, Roura D, Hughes JA. Evaluation of the transfection property of a peptide ligand for the fibroblast growth factor receptor as part of PEGylated polyethylenimine polyplex. Journal of Drug Targeting. 16: 79-89. PMID 18172824 DOI: 10.1080/10611860701733328 |
0.311 |
|
2007 |
Yadava P, Roura D, Hughes JA. Evaluation of two cationic delivery systems for siRNA. Oligonucleotides. 17: 213-22. PMID 17638525 DOI: 10.1089/Oli.2006.0062 |
0.794 |
|
2007 |
Hirko AC, Meyer EM, King MA, Hughes JA. Peripheral transgene expression of plasma gelsolin reduces amyloid in transgenic mouse models of Alzheimer's disease Molecular Therapy. 15: 1623-1629. PMID 17609655 DOI: 10.1038/sj.mt.6300253 |
0.758 |
|
2007 |
Rao G, Yadava P, Hughes J. Rationally Designed Synthetic Vectors for Gene Delivery The Open Drug Delivery Journal. 1: 7-19. DOI: 10.2174/1874126600701010007 |
0.784 |
|
2006 |
Zhang C, Yadava P, Sun J, Hughes JA. A gene delivery approach for antimicrobials: expression of defensins. Journal of Drug Targeting. 14: 646-51. PMID 17090400 DOI: 10.1080/10611860600907767 |
0.771 |
|
2006 |
Yadava P, Zhang C, Sun J, Hughes JA. Antimicrobial activities of human beta-defensins against Bacillus species. International Journal of Antimicrobial Agents. 28: 132-7. PMID 16797165 DOI: 10.1016/J.Ijantimicag.2006.02.021 |
0.758 |
|
2006 |
Gong Y, Meyer EM, Meyers CA, Klein RL, King MA, Hughes JA. Memory-related deficits following selective hippocampal expression of Swedish mutation amyloid precursor protein in the rat. Experimental Neurology. 200: 371-7. PMID 16780838 DOI: 10.1016/J.Expneurol.2006.02.136 |
0.336 |
|
2006 |
Yadava P, Buethe D, Hughes JA. Nonviral gene therapy with surfactants Acs Symposium Series. 923: 198-216. |
0.339 |
|
2005 |
Wu K, Meyer EM, Bennett JA, Meyers CA, Hughes JA, King MA. AAV2/5-mediated NGF gene delivery protects septal cholinergic neurons following axotomy. Brain Research. 1061: 107-13. PMID 16226726 DOI: 10.1016/J.Brainres.2005.08.056 |
0.349 |
|
2004 |
Fuchs S, Buethe D, Khanna A, Yadava P, Hughes J. Sulfhydryl based cationic surfactants and the impact of polyanions on disulfide bond formation: implications for gene transfer vectors. Journal of Drug Targeting. 12: 347-53. PMID 15545084 DOI: 10.1080/10611860400000649 |
0.776 |
|
2004 |
Gong Y, Chen S, Sonntag CF, Sumners C, Klein RL, King MA, Hughes JA, Meyer EM. Recombinant adeno-associated virus serotype 2 effectively transduces primary rat brain astrocytes and microglia. Brain Research. Brain Research Protocols. 14: 18-24. PMID 15519948 DOI: 10.1016/J.Brainresprot.2004.08.001 |
0.329 |
|
2004 |
Coulen H, Hughes J, Talton J, Hochhaus G. A novel method for polymer coating of plasmid DNA: initial investigations into the use of pulse laser deposition and gene delivery. Journal of Drug Targeting. 12: 237-41. PMID 15506172 DOI: 10.1080/10611860410001723108 |
0.314 |
|
2004 |
Wu K, Meyers CA, Bennett JA, King MA, Meyer EM, Hughes JA. Polyethylenimine-mediated NGF gene delivery protects transected septal cholinergic neurons. Brain Research. 1008: 284-7. PMID 15145767 DOI: 10.1016/J.Brainres.2004.02.051 |
0.358 |
|
2004 |
Zhang C, Yadava P, Hughes J. Polyethylenimine strategies for plasmid delivery to brain-derived cells. Methods (San Diego, Calif.). 33: 144-50. PMID 15121169 DOI: 10.1016/J.Ymeth.2003.11.004 |
0.786 |
|
2003 |
Chancham P, van Ijperen T, McDoom I, Hughes JA. Nucleic acid-matrix attachment recognition regions--as facilitators in plasmid transfer. Journal of Drug Targeting. 11: 205-13. PMID 14578107 DOI: 10.1080/10611860310001603823 |
0.782 |
|
2003 |
Wu K, Klein RL, Meyers CA, King MA, Hughes JA, Millard WJ, Meyer EM. Long-term neuronal effects and disposition of ectopic preproNGF gene transfer into the rat septum. Human Gene Therapy. 14: 1463-72. PMID 14577926 DOI: 10.1089/104303403769211673 |
0.335 |
|
2003 |
Xiao W, Scott TM, Feng L, Yu Z, Wang L, Hughes JA, Liu H. Acetylated low-density lipoprotein-encapsulated cholesteryl 1,3-diiopanoate glyceryl ether for the detection of atherosclerosis in rabbits. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 44: 770-3. PMID 12732679 |
0.588 |
|
2003 |
Hirko A, Tang F, Hughes JA. Cationic lipid vectors for plasmid DNA delivery. Current Medicinal Chemistry. 10: 1185-93. PMID 12678793 DOI: 10.2174/0929867033457412 |
0.79 |
|
2002 |
Hirko AC, Buethe DD, Meyer EM, Hughes JA. Plasmid delivery in the rat brain Bioscience Reports. 22: 297-308. PMID 12428906 DOI: 10.1023/A:1020194807665 |
0.802 |
|
2002 |
Xiao W, Warrington KH, Hearing P, Hughes J, Muzyczka N. Adenovirus-facilitated nuclear translocation of adeno-associated virus type 2. Journal of Virology. 76: 11505-17. PMID 12388712 DOI: 10.1128/Jvi.76.22.11505-11517.2002 |
0.657 |
|
2002 |
Klein RL, Hamby ME, Gong Y, Hirko AC, Wang S, Hughes JA, King MA, Meyer EM. Dose and promoter effects of adeno-associated viral vector for green fluorescent protein expression in the rat brain. Experimental Neurology. 176: 66-74. PMID 12093083 DOI: 10.1006/Exnr.2002.7942 |
0.78 |
|
2001 |
Tang F, Hughes JA. Use of disulfide cationic lipids in plasmid DNA delivery. Methods in Molecular Medicine. 65: 79-88. PMID 21318746 DOI: 10.1385/1-59259-139-6:79 |
0.752 |
|
2001 |
Chancham P, Hughes JA. Relationship between plasmid DNA topological forms and in vitro transfection. Journal of Liposome Research. 11: 139-52. PMID 19530929 DOI: 10.1081/Lpr-100108458 |
0.793 |
|
2001 |
Ajmani PS, Wang W, Tang F, King MA, Meyer EM, Hughes JA. Transgene delivery with a cationic lipid in the presence of amyloid β (βAP) peptide Neurochemical Research. 26: 195-202. PMID 11495542 DOI: 10.1023/A:1010956231321 |
0.732 |
|
2001 |
Liang Y, Belford S, Tang F, Prokai L, Simpkins JW, Hughes JA. Membrane fluidity effects of estratrienes. Brain Research Bulletin. 54: 661-8. PMID 11403993 DOI: 10.1016/S0361-9230(01)00483-X |
0.694 |
|
2001 |
Houk BE, Martin R, Hochhaus G, Hughes JA. Pharmacokinetics of plasmid DNA in the rat. Pharmaceutical Research. 18: 67-74. PMID 11336355 DOI: 10.1023/A:1011078711008 |
0.73 |
|
2001 |
Chancham P, Hughes JA. Relationship between plasmid DNA topological forms and in vitro transfection Journal of Liposome Research. 11: 139-152. DOI: 10.1081/LPR-100108458 |
0.794 |
|
2001 |
Tang F, Hughes JA. Synthesis and evaluation of a quaternary amino disulfide cationic lipid in plasmid DNA delivery S.T.P. Pharma Sciences. 11: 83-90. |
0.323 |
|
2000 |
Liang E, Rosenblatt MN, Ajmani PS, Hughes JA. Biodegradable pH-sensitive surfactants (BPS) in liposome-mediated nucleic acid cellular uptake and distribution. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 11: 199-205. PMID 11042225 DOI: 10.1016/S0928-0987(00)00101-9 |
0.345 |
|
2000 |
Wu P, Xiao W, Conlon T, Hughes J, Agbandje-McKenna M, Ferkol T, Flotte T, Muzyczka N. Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism. Journal of Virology. 74: 8635-47. PMID 10954565 DOI: 10.1128/Jvi.74.18.8635-8647.2000 |
0.657 |
|
2000 |
Ismail FA, Napaporn J, Hughes JA, Brazeau GA. In situ gel formulations for gene delivery: release and myotoxicity studies. Pharmaceutical Development and Technology. 5: 391-7. PMID 10934739 DOI: 10.1081/Pdt-100100555 |
0.356 |
|
2000 |
Wang S, Bui V, Hughes JA, King MA, Meyer EM. Adeno-associated virus mediated gene transfer into primary rat brain neuronal and glial cultures: Enhancement with the pH-sensitive surfactant dodecyl 2-(1'-imidazolyl) propionate Neurochemistry International. 37: 1-6. PMID 10781840 DOI: 10.1016/S0197-0186(00)00007-3 |
0.407 |
|
2000 |
Poxon SW, Hughes JA. The effect of lyophilization on plasmid DNA activity Pharmaceutical Development and Technology. 5: 115-122. PMID 10669925 DOI: 10.1081/Pdt-100100526 |
0.398 |
|
2000 |
Hughes J, Astriab A, Yoo H, Alahari S, Liang E, Sergueev D, Shaw BR, Juliano RL. In vitro transport and delivery of antisense oligonucleotides. Methods in Enzymology. 313: 342-58. PMID 10595365 DOI: 10.1016/S0076-6879(00)13021-6 |
0.347 |
|
1999 |
Houk BE, Hochhaus G, Hughes JA. Kinetic modeling of plasmid DNA degradation in rat plasma Aaps Pharmsci [Electronic Resource]. 1. PMID 11741205 DOI: 10.1208/Ps010309 |
0.718 |
|
1999 |
Wang W, Ajmani PS, Meyer EM, Simpkins JW, Hughes JA. Pre-exposure of cells to cationic lipids enhances transgene delivery and expression in a tissue culture cell line. Journal of Drug Targeting. 7: 207-11. PMID 10680976 DOI: 10.3109/10611869909085503 |
0.424 |
|
1999 |
Ajmani PS, Tang F, Krishnaswami S, Meyer EM, Sumners C, Hughes JA. Enhanced transgene expression in rat brain cell cultures with a disulfide-containing cationic lipid Neuroscience Letters. 277: 141-144. PMID 10626833 DOI: 10.1016/S0304-3940(99)00856-3 |
0.747 |
|
1999 |
Tang F, Hughes JA. Synthesis of a single-tailed cationic lipid and investigation of its transfection Journal of Controlled Release. 62: 345-358. PMID 10528072 DOI: 10.1016/S0168-3659(99)00158-3 |
0.75 |
|
1999 |
Tang F, Hughes JA. Use of dithiodiglycolic acid as a tether for cationic lipids decreases the cytotoxicity and increases transgene expression of plasmid DNA in vitro Bioconjugate Chemistry. 10: 791-796. PMID 10502344 DOI: 10.1021/Bc990016I |
0.735 |
|
1999 |
Ajmani PS, Hughes JA. 3β [N-(N′, N′-dimethylaminoethane)-carbamoyl] cholesterol (DC-chol)-mediated gene delivery to primary rat neurons: Characterization and mechanism Neurochemical Research. 24: 699-703. PMID 10344600 DOI: 10.1023/A:1021012727796 |
0.365 |
|
1999 |
Poxon SW, Hughes JA. Characterization of endotoxin and cationic liposome interaction Pharmaceutical Development and Technology. 4: 135-143. PMID 10231875 DOI: 10.1081/PDT-100101348 |
0.31 |
|
1999 |
Tang F, Wang W, Hughes JA. Cationic liposomes containing disulfide bonds in delivery of plasmid DNA Journal of Liposome Research. 9: 331-347. DOI: 10.3109/08982109909018654 |
0.778 |
|
1998 |
Brazeau GA, Attia S, Poxon S, Hughes JA. In Vitro Myotoxicity of Selected Cationic Macromolecules Used in Non-Viral Gene Delivery Pharmaceutical Research. 15: 680-684. PMID 9619774 DOI: 10.1023/A:1011954516233 |
0.447 |
|
1998 |
Aronsohn AI, Hughes JA. Nuclear localization signal peptides enhance cationic liposome-mediated gene therapy Journal of Drug Targeting. 5: 163-169. PMID 9606006 DOI: 10.3109/10611869808995871 |
0.422 |
|
1998 |
Liang E, Hughes J. Characterization Of A Ph-Sensitive Surfactant, Dodecyl-2-(1'-Imidazolyl) Propionate (Dip), And Preliminary Studies In Liposome Mediated Gene Transfer Biochimica Et Biophysica Acta. 1369: 39-50. PMID 9528672 DOI: 10.1016/S0005-2736(97)00172-7 |
0.435 |
|
1998 |
Weissig V, Lasch J, Erdos G, Meyer HW, Rowe TC, Hughes J. DQAsomes: a novel potential drug and gene delivery system made from Dequalinium. Pharmaceutical Research. 15: 334-337. PMID 9523323 DOI: 10.1023/A:1011991307631 |
0.362 |
|
1998 |
Tang F, Hughes JA. Introduction of a disulfide bond into a cationic lipid enhances transgene expression of plasmid DNA Biochemical and Biophysical Research Communications. 242: 141-145. PMID 9439625 DOI: 10.1006/Bbrc.1997.7923 |
0.757 |
|
1996 |
Hughes JA, Aronsohn AI, Avrutskaya AV, Juliano RL. Evaluation of adjuvants that enhance the effectiveness of antisense oligodeoxynucleotides Pharmaceutical Research. 13: 404-410. PMID 8692733 DOI: 10.1023/A:1016044609972 |
0.368 |
|
Show low-probability matches. |