Gwendolyn A. Sowa - Publications

Affiliations: 
Bioengineering University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Biomedical Engineering, Biomechanics Biophysics, Molecular Biology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wang D, Hartman R, Han C, Zhou CM, Couch B, Malkamaki M, Roginskaya V, Van Houten B, Mullett SJ, Wendell SG, Jurczak MJ, Kang J, Lee J, Sowa G, Vo N. Lactate oxidative phosphorylation by annulus fibrosus cells: evidence for lactate-dependent metabolic symbiosis in intervertebral discs. Arthritis Research & Therapy. 23: 145. PMID 34020698 DOI: 10.1186/s13075-021-02501-2  0.599
2020 Han Y, Zhou CM, Shen H, Tan J, Dong Q, Zhang L, McGowan SJ, Zhao J, Sowa GA, Kang JD, Niedernhofer LJ, Robbins PD, Vo NN. Attenuation of ataxia telangiectasia mutated signalling mitigates age-associated intervertebral disc degeneration. Aging Cell. PMID 32567210 DOI: 10.1111/Acel.13162  0.323
2019 Tisherman R, Hartman R, Hariharan K, Vaudreuil N, Sowa G, Schneider M, Timko M, Bell K. Biomechanical contribution of the alar ligaments to upper cervical stability. Journal of Biomechanics. 109508. PMID 31813563 DOI: 10.1016/J.Jbiomech.2019.109508  0.614
2019 Huang W, Kabbani N, Brannan T, Lin MK, Theiss M, Hamilton J, Ecklund J, Conley YP, Vodovotz Y, Brienza D, Wagner AK, Robbins EA, Sowa GA, Lipsky R. Association of a functional polymorphism in the CHRFAM7A gene with inflammatory response mediators and neuropathic pain after spinal cord injury. Journal of Neurotrauma. PMID 30924722 DOI: 10.1089/Neu.2018.6200  0.306
2019 Patil P, Dong Q, Wang D, Chang J, Wiley C, Demaria M, Lee J, Kang J, Niedernhofer LJ, Robbins PD, Sowa G, Campisi J, Zhou D, Vo N. Systemic clearance of p16 -positive senescent cells mitigates age-associated intervertebral disc degeneration. Aging Cell. e12927. PMID 30900385 DOI: 10.1111/Acel.12927  0.304
2019 Yurube T, Buchser WJ, Moon HJ, Hartman RA, Takayama K, Kawakami Y, Nishida K, Kurosaka M, Vo NV, Kang JD, Lotze MT, Sowa GA. Serum and nutrient deprivation increase autophagic flux in intervertebral disc annulus fibrosus cells: an in vitro experimental study. European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. PMID 30847707 DOI: 10.1007/S00586-019-05910-9  0.631
2017 Ngo K, Patil P, McGowan SJ, Niedernhofer LJ, Robbins PD, Kang J, Sowa G, Vo N. Senescent intervertebral disc cells exhibit perturbed matrix homeostasis phenotype. Mechanisms of Ageing and Development. PMID 28830687 DOI: 10.1016/J.Mad.2017.08.007  0.361
2017 Vaudreuil N, Kadow T, Yurube T, Hartman R, Ngo K, Dong Q, Pohl P, Coelho JP, Kang J, Vo N, Sowa G. NSAID use in intervertebral disc degeneration: what are the effects on matrix homeostasis in vivo? The Spine Journal : Official Journal of the North American Spine Society. PMID 28416438 DOI: 10.1016/J.Spinee.2017.04.012  0.648
2017 Russo F, Hartman RA, Bell KM, Vo N, Sowa GA, Kang JD, Vadalà G, Denaro V. Biomechanical Evaluation of Transpedicular Nucleotomy With Intact Annulus Fibrosus. Spine. 42: E193-E201. PMID 28207656 DOI: 10.1097/Brs.0000000000001762  0.617
2016 Russo F, Hartman RA, Bell KM, Vo N, Sowa GA, Kang JD, Vadalà G, Denaro V. Biomechanical Evaluation of Transpedicular Nucleotomy with Intact Annulus Fibrosus. Spine. PMID 27390913 DOI: 10.1097/BRS.0000000000001762  0.588
2016 Pohl PH, Lozito TP, Cuperman T, Yurube T, Moon HJ, Ngo K, Tuan RS, Croix CS, Sowa GA, Rodrigues LM, Kang JD, Vo NV. Catabolic effects of endothelial cell-derived microparticles on disc cells: Implications in intervertebral disc neovascularization and degeneration. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 27246627 DOI: 10.1002/Jor.23298  0.324
2016 Hartman RA, Tisherman RE, Wang C, Bell KM, Lee JY, Sowa GA, Kang JD. Mechanical role of the posterior column components in the cervical spine. European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. PMID 27052405 DOI: 10.1007/S00586-016-4541-1  0.605
2016 Vo NV, Hartman RA, Patil PR, Risbud MV, Kletsas D, Iatridis JC, Hoyland JA, Le Maitre CL, Sowa GA, Kang JD. Molecular mechanisms of biological aging in intervertebral discs. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 26890203 DOI: 10.1002/Jor.23195  0.615
2016 Russo F, Vadalà G, Hartman RA, Bell KM, Sowa GA, Vo N, Kang JD, Denaro V. Biomechanical Evaluation of the Transpedicular Nucleotomy with Intact Anulus Fibrosus Global Spine Journal. 6. DOI: 10.1055/S-0036-1582887  0.601
2016 Vaudreuil NJ, Vo NV, Sowa GA. Biologic Treatments in Intervertebral Disc Degeneration: Protein-Based and Cell-Based Therapies Operative Techniques in Orthopaedics. 26: 189-197. DOI: 10.1053/J.Oto.2016.06.009  0.323
2015 Ziraldo C, Solovyev A, Allegretti A, Krishnan S, Henzel MK, Sowa GA, Brienza D, An G, Mi Q, Vodovotz Y. A Computational, Tissue-Realistic Model of Pressure Ulcer Formation in Individuals with Spinal Cord Injury. Plos Computational Biology. 11: e1004309. PMID 26111346 DOI: 10.1016/J.Jcrc.2012.10.061  0.306
2015 Hartman RA, Yurube T, Ngo K, Merzlak NE, Debski RE, Brown BN, Kang JD, Sowa GA. Biological responses to flexion/extension in spinal segments ex-vivo. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 1255-64. PMID 25865090 DOI: 10.1002/Jor.22900  0.645
2015 Hartman RA, Bell KM, Quan B, Nuzhao Y, Sowa GA, Kang JD. Needle puncture in rabbit functional spinal units alters rotational biomechanics. Journal of Spinal Disorders & Techniques. 28: E146-53. PMID 25370985 DOI: 10.1097/Bsd.0000000000000196  0.591
2015 Ouyang Z, Han Y, Richman AH, Dong Q, Huang W, Tang Y, Wang B, Vo N, Sowa G, Kamg JD. 616. Disc Gene Therapy: Development of a Novel Inducible System To Regulate Expression of the Therapeutic Transgene TIMP1 Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34225-3  0.333
2015 Hartman RA, Tisherman RT, Hariharan K, Schneider MJ, Sowa GA, Kang JD. Robotic Simulation of Clinical Exams: Describing the Mechanical Effect of Alar Ligament Injury The Spine Journal. 15: S182. DOI: 10.1016/J.Spinee.2015.07.229  0.595
2014 Moon HJ, Yurube T, Lozito TP, Pohl P, Hartman RA, Sowa GA, Kang JD, Vo NV. Effects of secreted factors in culture medium of annulus fibrosus cells on microvascular endothelial cells: elucidating the possible pathomechanisms of matrix degradation and nerve in-growth in disc degeneration. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 22: 344-54. PMID 24361793 DOI: 10.1016/J.Joca.2013.12.008  0.626
2014 Henrikson KJ, Pohl P, Lin H, Hartman RA, Tuan RS, Kang JD, Vo N, Sowa GA. Nucleous Pulposus Tissue Engineering Using a Novel Photopolymerizable Hydrogel and Minimally Invasive Delivery The Spine Journal. 14: S173. DOI: 10.1016/J.Spinee.2014.08.416  0.598
2014 Pohl P, Lozito TP, Cuperman T, Yurube T, Ngo K, Tuan RS, Sowa GA, Rodriques LMR, Kang JD, Vo N. Harmful Effects of Endothelial Cell-Derived Microparticles on Matrix Metabolism by Intervertebral Disc Cells The Spine Journal. 14: S161-S162. DOI: 10.1016/J.Spinee.2014.08.390  0.31
2013 Nasto LA, Robinson AR, Ngo K, Clauson CL, Dong Q, St Croix C, Sowa G, Pola E, Robbins PD, Kang J, Niedernhofer LJ, Wipf P, Vo NV. Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 31: 1150-7. PMID 23389888 DOI: 10.1002/Jor.22320  0.305
2013 Leckie SK, Sowa GA, Bechara BP, Hartman RA, Coelho JP, Witt WT, Dong QD, Bowman BW, Bell KM, Vo NV, Kramer BC, Kang JD. Injection of human umbilical tissue-derived cells into the nucleus pulposus alters the course of intervertebral disc degeneration in vivo. The Spine Journal : Official Journal of the North American Spine Society. 13: 263-72. PMID 23384411 DOI: 10.1016/J.Spinee.2012.12.004  0.64
2013 Vo NV, Hartman RA, Yurube T, Jacobs LJ, Sowa GA, Kang JD. Expression and regulation of metalloproteinases and their inhibitors in intervertebral disc aging and degeneration. The Spine Journal : Official Journal of the North American Spine Society. 13: 331-41. PMID 23369495 DOI: 10.1016/J.Spinee.2012.02.027  0.636
2013 Jacobs L, Vo N, Coelho JP, Dong Q, Bechara B, Woods B, Hempen E, Hartman R, Preuss H, Balk J, Kang J, Sowa G. Glucosamine supplementation demonstrates a negative effect on intervertebral disc matrix in an animal model of disc degeneration. Spine. 38: 984-90. PMID 23324939 DOI: 10.1097/Brs.0B013E318286B31E  0.64
2012 Sowa GA, Coelho JP, Vo NV, Pacek C, Westrick E, Kang JD. Cells from degenerative intervertebral discs demonstrate unfavorable responses to mechanical and inflammatory stimuli: a pilot study. American Journal of Physical Medicine & Rehabilitation / Association of Academic Physiatrists. 91: 846-55. PMID 22760106 DOI: 10.1097/Phm.0B013E31825F145A  0.323
2012 Hartman RA, Bell KM, Debski RE, Kang JD, Sowa GA. Novel ex-vivo mechanobiological intervertebral disc culture system. Journal of Biomechanics. 45: 382-5. PMID 22099147 DOI: 10.1016/J.Jbiomech.2011.10.036  0.643
2012 Leckie SK, Bechara BP, Hartman RA, Sowa GA, Woods BI, Coelho JP, Witt WT, Dong QD, Bowman BW, Bell KM, Vo NV, Wang B, Kang JD. Injection of AAV2-BMP2 and AAV2-TIMP1 into the nucleus pulposus slows the course of intervertebral disc degeneration in an in vivo rabbit model. The Spine Journal : Official Journal of the North American Spine Society. 12: 7-20. PMID 22023960 DOI: 10.1016/J.Spinee.2011.09.011  0.633
2012 Vadalà G, Sowa G, Hubert M, Gilbertson LG, Denaro V, Kang JD. Mesenchymal stem cells injection in degenerated intervertebral disc: cell leakage may induce osteophyte formation. Journal of Tissue Engineering and Regenerative Medicine. 6: 348-55. PMID 21671407 DOI: 10.1002/Term.433  0.314
2012 Vo N, Sowa GA, Kang JD, Studer R. COX-2 Inhibition Mitigates Cytokine-Mediated Suppression of Matrix Proteoglycan and Collagen Syntheses in Human Disc Cells The Spine Journal. 12. DOI: 10.1016/J.Spinee.2012.08.291  0.327
2011 Wang D, Vo NV, Sowa GA, Hartman RA, Ngo K, Choe SR, Witt WT, Dong Q, Lee JY, Niedernhofer LJ, Kang JD. Bupivacaine decreases cell viability and matrix protein synthesis in an intervertebral disc organ model system. The Spine Journal : Official Journal of the North American Spine Society. 11: 139-46. PMID 21296298 DOI: 10.1016/J.Spinee.2010.11.017  0.654
2011 Sowa G, Westrick E, Pacek C, Coelho P, Patel D, Vadala G, Georgescu H, Vo N, Studer R, Kang J. In vitro and in vivo testing of a novel regulatory system for gene therapy for intervertebral disc degeneration. Spine. 36: E623-8. PMID 21224765 DOI: 10.1097/Brs.0B013E3181Ed11C1  0.307
2011 Sowa GA, Coelho JP, Bell KM, Zorn AS, Vo NV, Smolinski P, Niyonkuru C, Hartman R, Studer RK, Kang JD. Alterations in gene expression in response to compression of nucleus pulposus cells. The Spine Journal : Official Journal of the North American Spine Society. 11: 36-43. PMID 21056011 DOI: 10.1016/J.Spinee.2010.09.019  0.65
2011 Leckie S, Bechara B, Hartman R, Sowa G, Woods B, Coelho P, Witt W, Dong Q, Bowman B, Bell K, Vo N, Wang B, Kang J. Injection of AAV2-BMP2 and AAV2-TIMP1 into the Nucleus Pulposus Slows the Course of Intervertebral Disc Degeneration by MRI, Histological, Serum Biochemical, and Biomechanical Criteria The Spine Journal. 11: S26. DOI: 10.1016/J.Spinee.2011.08.074  0.621
2011 Sowa GA, Bell K, Coelho P, Debski RE, Hartman R, Kang JD, Vo NV, Witt W. Poster 125 Development of a Novel Ex Vivo Mechanobiological System to Examine the Biologic Effects of Loading on the Intervertebral Disk Pm&R. 3: S212-S212. DOI: 10.1016/J.Pmrj.2011.08.159  0.619
2010 Vo N, Seo HY, Robinson A, Sowa G, Bentley D, Taylor L, Studer R, Usas A, Huard J, Alber S, Watkins SC, Lee J, Coehlo P, Wang D, Loppini M, et al. Accelerated aging of intervertebral discs in a mouse model of progeria. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 28: 1600-7. PMID 20973062 DOI: 10.1002/Jor.21153  0.304
2010 Vo NV, Sowa GA, Kang JD, Seidel C, Studer RK. Prostaglandin E2 and prostaglandin F2α differentially modulate matrix metabolism of human nucleus pulposus cells. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 28: 1259-66. PMID 20839316 DOI: 10.1002/Jor.21157  0.35
2010 Lee H, Sowa G, Vo N, Vadala G, O'Connell S, Studer R, Kang J. Effect of bupivacaine on intervertebral disc cell viability. The Spine Journal : Official Journal of the North American Spine Society. 10: 159-66. PMID 19800297 DOI: 10.1016/J.Spinee.2009.08.445  0.337
2010 Woods BI, Sowa G, Vo N, Kang JD. A Change in Strategy: The Use of Regenerative Medicine and Tissue Engineering to Augment the Course of Intervertebral Disc Degeneration Operative Techniques in Orthopaedics. 20: 144-153. DOI: 10.1053/J.Oto.2009.10.009  0.322
2009 Kim JH, Deasy BM, Seo HY, Studer RK, Vo NV, Georgescu HI, Sowa GA, Kang JD. Differentiation of intervertebral notochordal cells through live automated cell imaging system in vitro. Spine. 34: 2486-93. PMID 19841610 DOI: 10.1097/Brs.0B013E3181B26Ed1  0.303
2009 Leckie S, Sowa G. Emerging Technologies for Degenerative Disk Disease: Potential Synergy Between Biochemical Signaling and Spinal Biomechanics Pm&R. 1: 466-470. PMID 19627934 DOI: 10.1016/J.Pmrj.2009.02.011  0.32
2008 Studer RK, Gilbertson LG, Georgescu H, Sowa G, Vo N, Kang JD. p38 MAPK inhibition modulates rabbit nucleus pulposus cell response to IL-1. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 26: 991-8. PMID 18302237 DOI: 10.1002/Jor.20604  0.301
2008 Vo N, Seidel C, Coelho P, Sowa G, Studer R, Lee J, Kang J. 198. Identification of Novel TNF-a Regulated Extracellular Matrix and Cell-matrix Adhesion Genes in Intervertebral Disc Cells: A Microarray Gene Profiling of Human Nucleus Pulposus Cells The Spine Journal. 8. DOI: 10.1016/J.Spinee.2008.06.237  0.331
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