David Malcolm MacLean, PhD - Publications

Affiliations: 
2017- Pharmacology and Physiology University of Rochester Medical Center, Rochester, NY, United States 
Area:
Biophysics of iGluRs and ASICs, pharmacology
Website:
macleanlab.net

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Carrillo E, Shaikh SA, Berka V, Durham RJ, Litwin DB, Lee G, MacLean DM, Nowak LM, Jayaraman V. Mechanism of modulation of AMPA receptors by TARP-γ8. The Journal of General Physiology. PMID 31748249 DOI: 10.1085/jgp.201912451  1
2018 MacLean DM, Durham RJ, Jayaraman V. Mapping the Conformational Landscape of Glutamate Receptors Using Single Molecule FRET. Trends in Neurosciences. PMID 30385052 DOI: 10.1016/j.tins.2018.10.003  1
2018 Chen J, Li L, Chen SR, Chen H, Xie JD, Sirrieh RE, MacLean DM, Zhang Y, Zhou MH, Jayaraman V, Pan HL. The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions. Cell Reports. 22: 2307-2321. PMID 29490268 DOI: 10.1016/j.celrep.2018.02.021  1
2017 Dolino DM, Chatterjee S, MacLean DM, Flatebo C, Bishop LDC, Shaikh SA, Landes CF, Jayaraman V. The structure-energy landscape of NMDA receptor gating. Nature Chemical Biology. PMID 28991238 DOI: 10.1038/nchembio.2487  1
2017 Coombs ID, MacLean DM, Jayaraman V, Farrant M, Cull-Candy SG. Dual Effects of TARP γ-2 on Glutamate Efficacy Can Account for AMPA Receptor Autoinactivation. Cell Reports. 20: 1123-1135. PMID 28768197 DOI: 10.1016/j.celrep.2017.07.014  1
2017 MacLean DM, Jayaraman V. Deactivation kinetics of acid-sensing ion channel 1a are strongly pH-sensitive. Proceedings of the National Academy of Sciences of the United States of America. PMID 28265090 DOI: 10.1073/pnas.1620508114  1
2016 Vitrac H, MacLean DM, Karlstaedt A, Taegtmeyer H, Jayaraman V, Bogdanov M, Dowhan W. Dynamic lipid-dependent modulation of protein topology by post-translational phosphorylation. The Journal of Biological Chemistry. PMID 27974465 DOI: 10.1074/jbc.M116.765719  1
2016 Shaikh SA, Dolino DM, Lee G, Chatterjee S, MacLean DM, Flatebo C, Landes CF, Jayaraman V. Stargazin Modulation of AMPA Receptors. Cell Reports. 17: 328-335. PMID 27705782 DOI: 10.1016/j.celrep.2016.09.014  1
2016 MacLean DM, Jayaraman V. Acid sensing ion channels are tuned to follow high frequency stimuli. The Journal of Physiology. PMID 26931316 DOI: 10.1113/JP271915  1
2016 Maclean DM. Constructing a rapid solution exchange system Neuromethods. 106: 165-183. DOI: 10.1007/978-1-4939-2812-5_12  1
2015 Vitrac H, MacLean DM, Jayaraman V, Bogdanov M, Dowhan W. Dynamic membrane protein topological switching upon changes in phospholipid environment. Proceedings of the National Academy of Sciences of the United States of America. PMID 26512118 DOI: 10.1073/pnas.1512994112  1
2015 Sirrieh RE, MacLean DM, Jayaraman V. A conserved structural mechanism of NMDA receptor inhibition: A comparison of ifenprodil and zinc. The Journal of General Physiology. PMID 26170175 DOI: 10.1085/jgp.201511422  1
2015 Sirrieh RE, MacLean DM, Jayaraman V. Subtype-dependent N-methyl-D-aspartate receptor amino-terminal domain conformations and modulation by spermine. The Journal of Biological Chemistry. 290: 12812-20. PMID 25829490 DOI: 10.1074/jbc.M115.649723  1
2014 MacLean DM, Ramaswamy SS, Du M, Howe JR, Jayaraman V. Stargazin promotes closure of the AMPA receptor ligand-binding domain. The Journal of General Physiology. 144: 503-12. PMID 25422502 DOI: 10.1085/jgp.201411287  1
2014 Lee G, MacLean DM, Ulrich H, Zhao X, Aronowski J, Jayaraman V. RNA based antagonist of NMDA receptors. Acs Chemical Neuroscience. 5: 559-67. PMID 24708087 DOI: 10.1021/cn500041k  1
2013 Ramaswamy SS, MacLean DM, Gorfe AA, Jayaraman V. Proton-mediated conformational changes in an acid-sensing ion channel. The Journal of Biological Chemistry. 288: 35896-903. PMID 24196950 DOI: 10.1074/jbc.M113.478982  1
2013 Sirrieh RE, MacLean DM, Jayaraman V. Amino-terminal domain tetramer organization and structural effects of zinc binding in the N-methyl-D-aspartate (NMDA) receptor. The Journal of Biological Chemistry. 288: 22555-64. PMID 23792960 DOI: 10.1074/jbc.M113.482356  1
2013 MacLean DM. CrossTalk opposing view: TARPs modulate AMPA receptor conformations before the gating transitions. The Journal of Physiology. 591: 1585-6; discussion 1. PMID 23547187 DOI: 10.1113/jphysiol.2012.247726  1
2013 Maclean DM. Rebuttal from David M. MacLean Journal of Physiology. 591: 1589. DOI: 10.1113/jphysiol.2013.251520  1
2012 Ramaswamy S, Cooper D, Poddar N, MacLean DM, Rambhadran A, Taylor JN, Uhm H, Landes CF, Jayaraman V. Role of conformational dynamics in α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor partial agonism. The Journal of Biological Chemistry. 287: 43557-64. PMID 23115239 DOI: 10.1074/jbc.M112.371815  1
2011 Maclean DM, Bowie D. Transmembrane AMPA receptor regulatory protein regulation of competitive antagonism: a problem of interpretation. The Journal of Physiology. 589: 5383-90. PMID 21969453 DOI: 10.1113/jphysiol.2011.219485  1
2011 Maclean DM, Wong AY, Fay AM, Bowie D. Cations but not anions regulate the responsiveness of kainate receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2136-44. PMID 21307250 DOI: 10.1523/JNEUROSCI.4314-10.2011  1
2009 MacLean DM. The delta2 glutamate-like receptor undergoes similar conformational changes as other ionotropic glutamate receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6767-8. PMID 19474303 DOI: 10.1523/JNEUROSCI.1456-09.2009  1
2007 Wong AY, MacLean DM, Bowie D. Na+/Cl- dipole couples agonist binding to kainate receptor activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6800-9. PMID 17581967 DOI: 10.1523/JNEUROSCI.0284-07.2007  1
2006 Kuang D, Yao Y, Maclean D, Wang M, Hampson DR, Chang BS. Ancestral reconstruction of the ligand-binding pocket of Family C G protein-coupled receptors. Proceedings of the National Academy of Sciences of the United States of America. 103: 14050-5. PMID 16966606 DOI: 10.1073/pnas.0604717103  1
Show low-probability matches.