Paul Cumming - Publications

Affiliations: 
Biological Psychiatry Ludwig Maximilians University, München, Bayern, Germany 
Area:
Dopamine, Imaging

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Cumming P, Gallinat J. Invited commentary: mapping the alteration in glutamate with GluCEST MRI in a mouse model of dopamine deficiency: An Editorial Highlight for 'Mapping the alterations in glutamate with GluCEST MRI in a mouse model of dopamine deficiency'. Journal of Neurochemistry. PMID 27747879 DOI: 10.1111/jnc.13759  1
2016 Ilhan H, Wang H, Gildehaus FJ, Wängler C, Herrler T, Todica A, Schlichtiger J, Cumming P, Bartenstein P, Hacker M, Haug AR. Nephroprotective effects of enalapril after [177Lu]-DOTATATE therapy using serial renal scintigraphies in a murine model of radiation-induced nephropathy. Ejnmmi Research. 6: 64. PMID 27515447 DOI: 10.1186/s13550-016-0219-2  1
2016 Adam A, Ibrahim Z, Mokhtar N, Shapiai MI, Cumming P, Mubin M. Evaluation of different time domain peak models using extreme learning machine-based peak detection for EEG signal. Springerplus. 5: 1036. PMID 27462484 DOI: 10.1186/s40064-016-2697-0  1
2016 Deutschländer A, la Fougère C, Boetzel K, Albert NL, Gildehaus FJ, Bartenstein P, Xiong G, Cumming P. Occupancy of pramipexole (Sifrol) at cerebral dopamine D2/3 receptors in Parkinson's disease patients. Neuroimage. Clinical. 12: 41-6. PMID 27408789 DOI: 10.1016/j.nicl.2016.06.007  1
2016 Olberg DE, Bauer N, Andressen KW, Hjørnevik T, Cumming P, Levy FO, Klaveness J, Haraldsen I, Sutcliffe JL. Brain penetrant small molecule (18)F-GnRH receptor (GnRH-R) antagonists: Synthesis and preliminary positron emission tomography imaging in rats. Nuclear Medicine and Biology. 43: 478-489. PMID 27236283 DOI: 10.1016/j.nucmedbio.2016.05.003  1
2016 Cumming P, Gryglewski G, Kranz GS, Lanzenberger R. Commentary: The serotonin transporter in depression: Meta-analysis of in vivo and post mortem findings and implications for understanding and treating depression. Journal of Affective Disorders. 199: 21-22. PMID 27057649 DOI: 10.1016/j.jad.2016.03.058  1
2015 Rademacher L, Prinz S, Winz O, Henkel K, Dietrich CA, Schmaljohann J, Mohammadkhani Shali S, Schabram I, Stoppe C, Cumming P, Hilgers RD, Kumakura Y, Coburn M, Mottaghy FM, Gründer G, et al. Effects of Smoking Cessation on Presynaptic Dopamine Function of Addicted Male Smokers. Biological Psychiatry. PMID 26803340 DOI: 10.1016/j.biopsych.2015.11.009  1
2015 Schlüter T, Winz O, Henkel K, Eggermann T, Mohammadkhani-Shali S, Dietrich C, Heinzel A, Decker M, Cumming P, Zerres K, Piel M, Mottaghy FM, Vernaleken I. MAOA-VNTR polymorphism modulates context-dependent dopamine release and aggressive behavior in males. Neuroimage. 125: 378-385. PMID 26481676 DOI: 10.1016/j.neuroimage.2015.10.031  1
2015 Vafaee MS, Gjedde A, Imamirad N, Vang K, Chakravarty MM, Lerch JP, Cumming P. Smoking normalizes cerebral blood flow and oxygen consumption after 12-hour abstention. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 699-705. PMID 25605288 DOI: 10.1038/jcbfm.2014.246  1
2015 Veselinovi? T, Vernaleken I, Janouschek H, Kellermann T, Paulzen M, Cumming P, Gründer G. Effects of anticholinergic challenge on psychopathology and cognition in drug-free patients with schizophrenia and healthy volunteers. Psychopharmacology. 232: 1607-17. PMID 25373869 DOI: 10.1007/s00213-014-3794-9  1
2014 Schabram I, Henkel K, Mohammadkhani Shali S, Dietrich C, Schmaljohann J, Winz O, Prinz S, Rademacher L, Neumaier B, Felzen M, Kumakura Y, Cumming P, Mottaghy FM, Gründer G, Vernaleken I. Acute and sustained effects of methylphenidate on cognition and presynaptic dopamine metabolism: an [18F]FDOPA PET study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14769-76. PMID 25355228 DOI: 10.1523/JNEUROSCI.1560-14.2014  1
2012 Nielsen MS, Andersen F, Cumming P, Møller A, Gjedde A, Sørensen JC, Bjarkam CR. Subthalamic high-frequency deep brain stimulation evaluated by positron emission tomography in a porcine Parkinson model Deep Brain Stimulation: New Developments, Procedures and Applications. 141-157.  1
2012 Nielsen MS, Andersen F, Cumming P, Møller A, Gjedde A, Sørensen JC, Bjarkam CR. Subthalamic high-frequency deep brain stimulation evaluated by positron emission tomography in a porcine Parkinson model Deep Brain Stimulation: New Developments, Procedures and Applications. 141-157.  1
2010 Kumakura Y, Vernaleken I, Buchholz HG, Borghammer P, Danielsen E, Gründer G, Heinz A, Bartenstein P, Cumming P. Age-dependent decline of steady state dopamine storage capacity of human brain: an FDOPA PET study. Neurobiology of Aging. 31: 447-63. PMID 18541344 DOI: 10.1016/j.neurobiolaging.2008.05.005  1
2008 Vernaleken I, Cumming P, Gründer G. Imaging studies - differential action of typical and atypical antipsychotics in a network perspective. Pharmacopsychiatry. 41: S60-9. PMID 18756422 DOI: 10.1055/s-0028-1082058  1
2008 Jensen SB, Di Santo R, Olsen AK, Pedersen K, Costi R, Cirilli R, Cumming P. Synthesis and cerebral uptake of 1-(1-[(11)C]methyl-1H-pyrrol-2-yl)-2-phenyl-2-(1-pyrrolidinyl)ethanone, a novel tracer for positron emission tomography studies of monoamine oxidase type A. Journal of Medicinal Chemistry. 51: 1617-22. PMID 18307289 DOI: 10.1021/jm701378e  1
2008 Borghammer P, Jonsdottir KY, Cumming P, Ostergaard K, Vang K, Ashkanian M, Vafaee M, Iversen P, Gjedde A. Normalization in PET group comparison studies--the importance of a valid reference region. Neuroimage. 40: 529-40. PMID 18258457 DOI: 10.1016/j.neuroimage.2007.12.057  1
2008 Kienast T, Siessmeier T, Wrase J, Braus DF, Smolka MN, Buchholz HG, Rapp M, Schreckenberger M, Rösch F, Cumming P, Gruender G, Mann K, Bartenstein P, Heinz A. Ratio of dopamine synthesis capacity to D2 receptor availability in ventral striatum correlates with central processing of affective stimuli. European Journal of Nuclear Medicine and Molecular Imaging. 35: 1147-58. PMID 18202844 DOI: 10.1007/s00259-007-0683-z  1
2008 Borghammer P, Vafaee M, Ostergaard K, Rodell A, Bailey C, Cumming P. Effect of memantine on CBF and CMRO2 in patients with early Parkinson's disease. Acta Neurologica Scandinavica. 117: 317-23. PMID 17927800 DOI: 10.1111/j.1600-0404.2007.00943.x  1
2008 Landvogt C, Mengel E, Bartenstein P, Buchholz HG, Schreckenberger M, Siessmeier T, Scheurich A, Feldmann R, Weglage J, Cumming P, Zepp F, Ullrich K. Reduced cerebral fluoro-L-dopamine uptake in adult patients suffering from phenylketonuria (Journal of Cerebral Blood Flow and Metabolism (2008) 28 (824-831) DOI: doi: 10.1038/sj.jcbfm.9600571) Journal of Cerebral Blood Flow and Metabolism. 28: 1070. DOI: 10.1038/sj.jcbfm.9600588  1
2007 Gramsbergen JB, Cumming P. Serotonin mediates rapid changes of striatal glucose and lactate metabolism after systemic 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") administration in awake rats. Neurochemistry International. 51: 8-15. PMID 17475367 DOI: 10.1016/j.neuint.2007.03.004  1
2007 Lind NM, Moustgaard A, Jelsing J, Vajta G, Cumming P, Hansen AK. The use of pigs in neuroscience: modeling brain disorders. Neuroscience and Biobehavioral Reviews. 31: 728-51. PMID 17445892 DOI: 10.1016/j.neubiorev.2007.02.003  1
2007 Pedersen K, Simonsen M, Østergaard SD, Munk OL, Rosa-Neto P, Olsen AK, Jensen SB, Møller A, Cumming P. Mapping the amphetamine-evoked changes in [11C]raclopride binding in living rat using small animal PET: modulation by MAO-inhibition. Neuroimage. 35: 38-46. PMID 17223363 DOI: 10.1016/j.neuroimage.2006.11.038  1
2007 Vernaleken I, Buchholz HG, Kumakura Y, Siessmeier T, Stoeter P, Bartenstein P, Cumming P, Gründer G. 'Prefrontal' cognitive performance of healthy subjects positively correlates with cerebral FDOPA influx: an exploratory [18F]-fluoro-L-DOPA-PET investigation. Human Brain Mapping. 28: 931-9. PMID 17133402 DOI: 10.1002/hbm.20325  1
2007 Watanabe H, Sakoh M, Andersen F, Rodell A, Sørensen JC, Østergaard L, Mouridsen K, Cumming P. Statistical mapping of effects of middle cerebral artery occlusion (MCAO) on blood flow and oxygen consumption in porcine brain. Journal of Neuroscience Methods. 160: 109-15. PMID 17129609 DOI: 10.1016/j.jneumeth.2006.08.016  1
2007 Vafaee MS, Borghammer P, Aanerud J, Cumming P, Gjedde A. Cerebral blood flow, cerebral oxygen metabolism, and atrophy in healthy aging Journal of Cerebral Blood Flow and Metabolism. 27: BP31-04W.  1
2006 Jakobsen S, Pedersen K, Smith DF, Jensen SB, Munk OL, Cumming P. Detection of alpha2-adrenergic receptors in brain of living pig with 11C-yohimbine. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 47: 2008-15. PMID 17138744  1
2006 Pedersen MD, Minuzzi L, Wirenfeldt M, Meldgaard M, Slidsborg C, Cumming P, Finsen B. Up-regulation of PK11195 binding in areas of axonal degeneration coincides with early microglial activation in mouse brain. The European Journal of Neuroscience. 24: 991-1000. PMID 16930426 DOI: 10.1111/j.1460-9568.2006.04975.x  1
2006 Siessmeier T, Kienast T, Wrase J, Larsen JL, Braus DF, Smolka MN, Buchholz HG, Schreckenberger M, Rösch F, Cumming P, Mann K, Bartenstein P, Heinz A. Net influx of plasma 6-[18F]fluoro-L-DOPA (FDOPA) to the ventral striatum correlates with prefrontal processing of affective stimuli. The European Journal of Neuroscience. 24: 305-13. PMID 16882026 DOI: 10.1111/j.1460-9568.2006.04903.x  1
2006 Jakobsen S, Kodahl GM, Olsen AK, Cumming P. Synthesis, radiolabeling and in vivo evaluation of [11C]RAL-01, a potential phosphodiesterase 5 radioligand. Nuclear Medicine and Biology. 33: 593-7. PMID 16843833 DOI: 10.1016/j.nucmedbio.2006.04.006  1
2006 Smith DF, Dyve S, Minuzzi L, Jakobsen S, Munk OL, Marthi K, Cumming P. Inhibition of [11C]mirtazapine binding by alpha2-adrenoceptor antagonists studied by positron emission tomography in living porcine brain. Synapse (New York, N.Y.). 59: 463-71. PMID 16565964 DOI: 10.1002/syn.20262  1
2006 Iversen P, Hansen DA, Bender D, Rodell A, Munk OL, Cumming P, Keiding S. Peripheral benzodiazepine receptors in the brain of cirrhosis patients with manifest hepatic encephalopathy. European Journal of Nuclear Medicine and Molecular Imaging. 33: 810-6. PMID 16550382 DOI: 10.1007/s00259-005-0052-8  1
2006 Cumming P, Pedersen MD, Minuzzi L, Mezzomo K, Danielsen EH, Iversen P, Aagaard D, Keiding S, Munk OL, Finsen B. Distribution of PK11195 binding sites in porcine brain studied by autoradiography in vitro and by positron emission tomography. Synapse (New York, N.Y.). 59: 418-26. PMID 16485266 DOI: 10.1002/syn.20257  1
2006 Jensen SB, Olsen AK, Pedersen K, Cumming P. Effect of monoamine oxidase inhibition on amphetamine-evoked changes in dopamine receptor availability in the living pig: a dual tracer PET study with [11C]harmine and [11C]raclopride. Synapse (New York, N.Y.). 59: 427-34. PMID 16485265 DOI: 10.1002/syn.20258  1
2006 Vernaleken I, Kumakura Y, Cumming P, Buchholz HG, Siessmeier T, Stoeter P, Müller MJ, Bartenstein P, Gründer G. Modulation of [18F]fluorodopa (FDOPA) kinetics in the brain of healthy volunteers after acute haloperidol challenge. Neuroimage. 30: 1332-9. PMID 16439159 DOI: 10.1016/j.neuroimage.2005.11.014  1
2006 Minuzzi L, Olsen AK, Bender D, Arnfred S, Grant R, Danielsen EH, Cumming P. Quantitative autoradiography of ligands for dopamine receptors and transporters in brain of Göttingen minipig: comparison with results in vivo. Synapse (New York, N.Y.). 59: 211-9. PMID 16385509 DOI: 10.1002/syn.20234  1
2006 Doudet DJ, Rosa-Neto P, Munk OL, Ruth TJ, Jivan S, Cumming P. Effect of age on markers for monoaminergic neurons of normal and MPTP-lesioned rhesus monkeys: a multi-tracer PET study. Neuroimage. 30: 26-35. PMID 16378735 DOI: 10.1016/j.neuroimage.2005.09.044  1
2006 Smith DF, Marthi K, Munk OL, Cumming P, Hansen SB, Jakobsen S. PET neuroimaging of [11C]mirtazapine enantiomers in pigs. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 16: 350-7. PMID 16361085 DOI: 10.1016/j.euroneuro.2005.10.008  1
2006 Kumakura Y, Gjedde A, Danielsen EH, Christensen S, Cumming P. Dopamine storage capacity in caudate and putamen of patients with early Parkinson's disease: correlation with asymmetry of motor symptoms. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 358-70. PMID 16079784 DOI: 10.1038/sj.jcbfm.9600202  1
2005 Borghammer P, Kumakura Y, Cumming P. Fluorodopa F 18 positron emission tomography and the progression of Parkinson disease. Archives of Neurology. 62: 1480; author reply 1. PMID 16157762 DOI: 10.1001/archneur.62.9.1480-a  1
2005 Heinz A, Siessmeier T, Wrase J, Buchholz HG, Gründer G, Kumakura Y, Cumming P, Schreckenberger M, Smolka MN, Rösch F, Mann K, Bartenstein P. Correlation of alcohol craving with striatal dopamine synthesis capacity and D2/3 receptor availability: a combined [18F]DOPA and [18F]DMFP PET study in detoxified alcoholic patients. The American Journal of Psychiatry. 162: 1515-20. PMID 16055774 DOI: 10.1176/appi.ajp.162.8.1515  1
2005 Lind NM, Gjedde A, Moustgaard A, Olsen AK, Jensen SB, Jakobsen S, Arnfred SM, Hansen AK, Hemmingsen RP, Cumming P. Behavioral response to novelty correlates with dopamine receptor availability in striatum of Göttingen minipigs. Behavioural Brain Research. 164: 172-7. PMID 16043240 DOI: 10.1016/j.bbr.2005.06.008  1
2005 Siessmeier T, Zhou Y, Buchholz HG, Landvogt C, Vernaleken I, Piel M, Schirrmacher R, Rösch F, Schreckenberger M, Wong DF, Cumming P, Gründer G, Bartenstein P. Parametric mapping of binding in human brain of D2 receptor ligands of different affinities. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 46: 964-72. PMID 15937307  1
2005 Sørensen M, Horsman MR, Cumming P, Munk OL, Keiding S. Effect of intratumoral heterogeneity in oxygenation status on FMISO PET, autoradiography, and electrode Po2 measurements in murine tumors. International Journal of Radiation Oncology, Biology, Physics. 62: 854-61. PMID 15936570 DOI: 10.1016/j.ijrobp.2005.02.044  1
2005 Andersen F, Watanabe H, Bjarkam C, Danielsen EH, Cumming P. Pig brain stereotaxic standard space: mapping of cerebral blood flow normative values and effect of MPTP-lesioning. Brain Research Bulletin. 66: 17-29. PMID 15925140 DOI: 10.1016/j.brainresbull.2005.02.033  1
2005 Rosa-Neto P, Lou HC, Cumming P, Pryds O, Karrebaek H, Lunding J, Gjedde A. Methylphenidate-evoked changes in striatal dopamine correlate with inattention and impulsivity in adolescents with attention deficit hyperactivity disorder. Neuroimage. 25: 868-76. PMID 15808987 DOI: 10.1016/j.neuroimage.2004.11.031  1
2005 Minuzzi L, Nomikos GG, Wade MR, Jensen SB, Olsen AK, Cumming P. Interaction between LSD and dopamine D2/3 binding sites in pig brain. Synapse (New York, N.Y.). 56: 198-204. PMID 15803496 DOI: 10.1002/syn.20141  1
2005 Gjedde A, Wong DF, Rosa-Neto P, Cumming P. Mapping neuroreceptors at work: on the definition and interpretation of binding potentials after 20 years of progress. International Review of Neurobiology. 63: 1-20. PMID 15797463 DOI: 10.1016/S0074-7742(05)63001-2  1
2005 Lind NM, Olsen AK, Moustgaard A, Jensen SB, Jakobsen S, Hansen AK, Arnfred SM, Hemmingsen RP, Gjedde A, Cumming P. Mapping the amphetamine-evoked dopamine release in the brain of the Göttingen minipig. Brain Research Bulletin. 65: 1-9. PMID 15680539 DOI: 10.1016/j.brainresbull.2004.08.007  1
2005 Jelsing J, Olsen AK, Cumming P, Gjedde A, Hansen AK, Arnfred S, Hemmingsen R, Pakkenberg B. A volumetric screening procedure for the Göttingen minipig brain. Experimental Brain Research. 162: 428-35. PMID 15668795 DOI: 10.1007/s00221-004-2026-7  1
2004 Rosa-Neto P, Gjedde A, Olsen AK, Jensen SB, Munk OL, Watanabe H, Cumming P. MDMA-evoked changes in [11C]raclopride and [11C]NMSP binding in living pig brain. Synapse (New York, N.Y.). 53: 222-33. PMID 15266554 DOI: 10.1002/syn.20053  1
2004 Bender D, Olsen AK, Marthi MK, Smith DF, Cumming P. PET evaluation of the uptake of N-[11C]methyl CP-643,051, an NK1 receptor antagonist, in the living porcine brain. Nuclear Medicine and Biology. 31: 699-704. PMID 15246360 DOI: 10.1016/j.nucmedbio.2004.03.005  1
2004 Rosa-Neto P, Doudet DJ, Cumming P. Gradients of dopamine D1- and D2/3-binding sites in the basal ganglia of pig and monkey measured by PET. Neuroimage. 22: 1076-83. PMID 15219579 DOI: 10.1016/j.neuroimage.2004.03.004  1
2004 Vafaee MS, ØStergaard K, Sunde N, Gjedde A, Dupont E, Cumming P. Focal changes of oxygen consumption in cerebral cortex of patients with Parkinson's disease during subthalamic stimulation. Neuroimage. 22: 966-74. PMID 15193628 DOI: 10.1016/j.neuroimage.2004.02.019  1
2004 Lou HC, Rosa P, Pryds O, Karrebaek H, Lunding J, Cumming P, Gjedde A. ADHD: increased dopamine receptor availability linked to attention deficit and low neonatal cerebral blood flow. Developmental Medicine and Child Neurology. 46: 179-83. PMID 14995087 DOI: 10.1017/S0012162204000313  1
2003 Kretzschmar M, Brust P, Zessin J, Cumming P, Bergmann R, Johannsen B. Autoradiographic imaging of the serotonin transporter in the brain of rats and pigs using S-([18F]fluoromethyl)-(+)-McN5652. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 13: 387-97. PMID 12957338 DOI: 10.1016/S0924-977X(03)00039-7  1
2003 Cumming P, Rosa-Neto P, Watanabe H, Smith D, Bender D, Clarke PB, Gjedde A. Effects of acute nicotine on hemodynamics and binding of [11C]raclopride to dopamine D2,3 receptors in pig brain. Neuroimage. 19: 1127-36. PMID 12880838 DOI: 10.1016/S1053-8119(03)00079-X  1
2003 Cumming P, Gillings NM, Jensen SB, Bjarkam C, Gjedde A. Kinetics of the uptake and distribution of the dopamine D(2,3) agonist (R)-N-[1-(11)C]n-propylnorapomorphine in brain of healthy and MPTP-treated Göttingen miniature pigs. Nuclear Medicine and Biology. 30: 547-53. PMID 12831994 DOI: 10.1016/S0969-8051(02)00448-1  1
2003 Jensen SB, Smith DF, Bender D, Jakobsen S, Peters D, Nielsen EØ, Olsen GM, Scheel-Krüger J, Wilson A, Cumming P. [11C]-NS 4194 versus [11C]-DASB for PET imaging of serotonin transporters in living porcine brain. Synapse (New York, N.Y.). 49: 170-7. PMID 12774301 DOI: 10.1002/syn.10222  1
2003 Gründer G, Vernaleken I, Müller MJ, Davids E, Heydari N, Buchholz HG, Bartenstein P, Munk OL, Stoeter P, Wong DF, Gjedde A, Cumming P. Subchronic haloperidol downregulates dopamine synthesis capacity in the brain of schizophrenic patients in vivo. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 787-94. PMID 12655326 DOI: 10.1038/sj.npp.1300103  1
2003 Audrain H, Bender D, Scheel-Krüger J, Nielsen E, Olsen GM, Peters D, Cumming P. Synthesis of the serotonin transporter ligand (±)-10-methyl 3-[6-nitro-(2-quinolinyl)]-3,10-diazabicyclo-[4.3.1]-decane ([ 11C-methyl]NS 2495) and first in vivo results Journal of Labelled Compounds and Radiopharmaceuticals. 46: 873-882. DOI: 10.1002/jlcr.726  1
2002 Cumming P, Wong DF, Dannals RF, Gillings N, Hilton J, Scheffel U, Gjedde A. The competition between endogenous dopamine and radioligands for specific binding to dopamine receptors. Annals of the New York Academy of Sciences. 965: 440-50. PMID 12105119  1
2002 Rosa Neto P, Lou H, Cumming P, Pryds O, Gjedde A. Methylphenidate-evoked potentiation of extracellular dopamine in the brain of adolescents with premature birth: correlation with attentional deficit. Annals of the New York Academy of Sciences. 965: 434-9. PMID 12105118  1
2002 Cumming P, Wong DF, Gillings N, Hilton J, Scheffel U, Gjedde A. Specific binding of [(11)C]raclopride and N-[(3)H]propyl-norapomorphine to dopamine receptors in living mouse striatum: occupancy by endogenous dopamine and guanosine triphosphate-free G protein. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 596-604. PMID 11973432 DOI: 10.1097/00004647-200205000-00011  1
2001 Watanabe H, Andersen F, Simonsen CZ, Evans SM, Gjedde A, Cumming P. MR-based statistical atlas of the Göttingen minipig brain. Neuroimage. 14: 1089-96. PMID 11697940 DOI: 10.1006/nimg.2001.0910  1
2001 Dagher A, Bleicher C, Aston JA, Gunn RN, Clarke PB, Cumming P. Reduced dopamine D1 receptor binding in the ventral striatum of cigarette smokers. Synapse (New York, N.Y.). 42: 48-53. PMID 11668590 DOI: 10.1002/syn.1098  1
2001 Danielsen EH, Smith DF, Andersen F, Gee AD, Bender D, Hansen SB, Hermansen F, Østergaard L, Cumming P, Gjedde A. FDOPA metabolism in the adult porcine brain: influence of tracer circulation time and VOI selection on estimates of striatal DOPA decarboxylation. Journal of Neuroscience Methods. 111: 157-68. PMID 11595282 DOI: 10.1016/S0165-0270(01)00453-8  1
2001 Hume S, Hirani E, Opacka-Juffry J, Myers R, Townsend C, Pike V, Grasby P. Effect of 5-HT on binding of [(11)C] WAY 100635 to 5-HT(IA) receptors in rat brain, assessed using in vivo microdialysis nd PET after fenfluramine. Synapse (New York, N.Y.). 41: 150-9. PMID 11400181 DOI: 10.1002/syn.1069  1
2001 Cumming P, Munk OL, Doudet D. Loss of metabolites from monkey striatum during PET with FDOPA. Synapse (New York, N.Y.). 41: 212-8. PMID 11391782 DOI: 10.1002/syn.1077  1
2001 Cumming P, Danielsen EH, Vafaee M, Falborg L, Steffensen E, Sørensen JC, Gillings N, Bender D, Marthi K, Andersen F, Munk O, Smith D, Møller A, Gjedde A. Normalization of markers for dopamine innervation in striatum of MPTP-lesioned miniature pigs with intrastriatal grafts. Acta Neurologica Scandinavica. 103: 309-15. PMID 11328207 DOI: 10.1034/j.1600-0404.2001.103005309.x  1
2001 Smith DF, Bender D, Marthi K, Cumming P, Hansen SB, Peters D, Nielsen EO, Scheel-Krüger J, Gjedde A. Synthesis and evaluation of racemic [(11)C]NS2456 and enantiomers as selective serotonin reuptake radiotracers for PET. Nuclear Medicine and Biology. 28: 265-70. PMID 11323236 DOI: 10.1016/S0969-8051(00)00175-X  1
2001 Gillings NM, Bender D, Falborg L, Marthi K, Munk OL, Cumming P. Kinetics of the metabolism of four PET radioligands in living minipigs. Nuclear Medicine and Biology. 28: 97-104. PMID 11182570 DOI: 10.1016/S0969-8051(00)00187-6  1
2001 Cumming P, Kretzschmar M, Brust P, Smith DF. Quantitative radioluminography of serotonin uptake sites in the porcine brain. Synapse (New York, N.Y.). 39: 351-5. PMID 11169786 DOI: 10.1002/1098-2396(20010315)39:4<351::AID-SYN1019>3.0.CO;2-M  1
2000 Ishizu K, Smith DF, Bender D, Danielsen E, Hansen SB, Wong DF, Cumming P, Gjedde A. Positron emission tomography of radioligand binding in porcine striatum in vivo: haloperidol inhibition linked to endogenous ligand release. Synapse (New York, N.Y.). 38: 87-101. PMID 10941144 DOI: 10.1002/1098-2396(200010)38:1<87::AID-SYN10>3.0.CO;2-C  1
2000 Rousset OG, Deep P, Kuwabara H, Evans AC, Gjedde AH, Cumming P. Effect of partial volume correction on estimates of the influx and cerebral metabolism of 6-[(18)F]fluoro-L-dopa studied with PET in normal control and Parkinson's disease subjects. Synapse (New York, N.Y.). 37: 81-9. PMID 10881028 DOI: 10.1002/1098-2396(200008)37:2<81::AID-SYN1>3.0.CO;2-#  1
2000 Danielsen EH, Cumming P, Andersen F, Bender D, Brevig T, Falborg L, Gee A, Gillings NM, Hansen SB, Hermansen F, Johansen J, Johansen TE, Dahl-Jørgensen A, Jørgensen HA, Meyer M, et al. The DaNeX study of embryonic mesencephalic, dopaminergic tissue grafted to a minipig model of Parkinson's disease: preliminary findings of effect of MPTP poisoning on striatal dopaminergic markers. Cell Transplantation. 9: 247-59. PMID 10811397  1
2000 Danielsen E, Smith D, Hermansen F, Gjedde A, Cumming P. Stimulation of DOPA decarboxylase in porcine brain with acute neuroleptics: An [ 18F]fluorodopa/PET study Neuroimage. 11: S39.  1
1999 Deep P, Dagher A, Sadikot A, Gjedde A, Cumming P. Stimulation of dopa decarboxylase activity in striatum of healthy human brain secondary to NMDA receptor antagonism with a low dose of amantadine. Synapse (New York, N.Y.). 34: 313-8. PMID 10529725 DOI: 10.1002/(SICI)1098-2396(19991215)34:4<313::AID-SYN7>3.0.CO;2-1  1
1999 Cumming P, Hermansen F, Gjedde A. Cerebral dopamine concentrations during levodopa treatment. Neurology. 53: 1374-5. PMID 10522916  1
1999 Cumming P, Yokoi F, Chen A, Deep P, Dagher A, Reutens D, Kapczinski F, Wong DF, Gjedde A. Pharmacokinetics of radiotracers in human plasma during positron emission tomography. Synapse (New York, N.Y.). 34: 124-34. PMID 10502311 DOI: 10.1002/(SICI)1098-2396(199911)34:2<124::AID-SYN5>3.0.CO;2-O  1
1999 Danielsen EH, Smith DF, Gee AD, Venkatachalam TK, Hansen SB, Hermansen F, Gjedde A, Cumming P. Cerebral 6-[(18)F]fluoro-L-DOPA (FDOPA) metabolism in pig studied by positron emission tomography. Synapse (New York, N.Y.). 33: 247-58. PMID 10421705 DOI: 10.1002/(SICI)1098-2396(19990915)33:4<247::AID-SYN1>3.0.CO;2-6  1
1999 Borbely K, Brooks RA, Wong DF, Burns RS, Cumming P, Gjedde A, Di Chiro G. NMSP binding to dopamine and serotonin receptors in MPTP-induced parkinsonism: relation to dopa therapy. Acta Neurologica Scandinavica. 100: 42-52. PMID 10416511  1
1999 Cumming P, Reith J, Gjedde A. Cocaine withdrawal and the cerebral influx of [18F]fluoro-L-DOPA (FDOPA) Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 395-8. PMID 10088142 DOI: 10.1016/S0893-133X(98)00096-7  1
1999 Thompson CJ, Sciascia P, Murthy K, Kecani S, Nikkinen L, del Campo E, Corbett JF, Bercier Y, Diksic M, Cumming P. 'ANIPET' a versatile PET scanner for imaging small animals Ieee Nuclear Science Symposium and Medical Imaging Conference. 2: 1264-1267.  1
1998 Léger G, Gjedde A, Kuwabara H, Guttman M, Cumming P. Effect of catechol-O-methyltransferase inhibition on brain uptake of [18F]fluorodopa: implications for compartmental modelling and clinical usefulness. Synapse (New York, N.Y.). 30: 351-61. PMID 9826227 DOI: 10.1002/(SICI)1098-2396(199812)30:4<351::AID-SYN2>3.0.CO;2-2  1
1998 Finnegan AP, Cumming PA, Piper ME. Critical incident stress debriefing following the terrorist bombing at Army Headquarters Northern Ireland. Journal of the Royal Army Medical Corps. 144: 5-10. PMID 9694008  1
1998 Cumming P, Ase A, Kuwabara H, Gjedde A. [3H]DOPA formed from [3H]tyrosine in living rat brain is not committed to dopamine synthesis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 491-9. PMID 9591841 DOI: 10.1097/00004647-199805000-00004  1
1998 Reith J, Cumming P, Gjedde A. Enhanced [3H]DOPA and [3H]dopamine turnover in striatum and frontal cortex in vivo linked to glutamate receptor antagonism. Journal of Neurochemistry. 70: 1979-85. PMID 9572282  1
1998 Cumming P, Gjedde A. Compartmental analysis of dopa decarboxylation in living brain from dynamic positron emission tomograms. Synapse (New York, N.Y.). 29: 37-61. PMID 9552174 DOI: 10.1002/(SICI)1098-2396(199805)29:1<37::AID-SYN4>3.0.CO;2-C  1
1997 Cumming P, Deep P, Rousset O, Evans A, Gjedde A. On the rate of decarboxylation of dopa to dopamine in living mammalian brain. Annals of the New York Academy of Sciences. 835: 274-308. PMID 9616781 DOI: 10.1111/j.1749-6632.1997.tb48637.x  1
1997 Deep P, Kuwabara H, Gjedde A, Cumming P. The kinetic behaviour of [3H]DOPA in living rat brain investigated by compartmental modelling of static autoradiograms. Journal of Neuroscience Methods. 78: 157-68. PMID 9497012 DOI: 10.1016/S0165-0270(97)00147-7  1
1997 Cumming P, Ase A, Laliberté C, Kuwabara H, Gjedde A. In vivo regulation of DOPA decarboxylase by dopamine receptors in rat brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 1254-60. PMID 9390657 DOI: 10.1097/00004647-199711000-00014  1
1997 Deep P, Gjedde A, Cumming P. On the accuracy of an [18F]FDOPA compartmental model: evidence for vesicular storage of [18F]fluorodopamine in vivo. Journal of Neuroscience Methods. 76: 157-65. PMID 9350967 DOI: 10.1016/S0165-0270(97)00094-0  1
1997 Cumming P, Gjedde A, Reith J. Controversies arising from recent FDOPA articles. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 38: 1267-71. PMID 9255163  1
1997 Cumming P, Ljubic-Thibal V, Laliberté C, Diksic M. The effect of unilateral neurotoxic lesions to serotonin fibres in the medial forebrain bundle on the metabolism of [3H]DOPA in the telencephalon of the living rat. Brain Research. 747: 60-9. PMID 9042528 DOI: 10.1016/S0006-8993(96)01227-9  1
1996 Li BY, Nalwalk JW, Barker LA, Cumming P, Parsons ME, Hough LB. Characterization of the antinociceptive properties of cimetidine and a structural analog. The Journal of Pharmacology and Experimental Therapeutics. 276: 500-8. PMID 8632315  1
1995 Kuwabara H, Cumming P, Yasuhara Y, Léger GC, Guttman M, Diksic M, Evans AC, Gjedde A. Regional striatal DOPA transport and decarboxylase activity in Parkinson's disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 36: 1226-31. PMID 7790948  1
1995 Cumming P, Kuwabara H, Ase A, Gjedde A. Regulation of DOPA decarboxylase activity in brain of living rat. Journal of Neurochemistry. 65: 1381-90. PMID 7643116  1
1995 Cumming P, Ase A, Diksic M, Harrison J, Jolly D, Kuwabara H, Laliberté C, Gjedde A. Metabolism and blood-brain clearance of L-3,4-dihydroxy-[3H]phenylalanine ([3H]DOPA) and 6-[18F]fluoro-L-DOPA in the rat. Biochemical Pharmacology. 50: 943-6. PMID 7575677 DOI: 10.1016/0006-2952(95)00216-M  1
1994 Cumming P, Gjedde A. Subclasses of histamine H3 antagonist binding sites in rat brain. Brain Research. 641: 203-7. PMID 8012822 DOI: 10.1016/0006-8993(94)90147-3  1
1994 Cumming P, Gjedde A, Vincent S. Histamine H3 binding sites in rat brain: localization in the nucleus of the solitary tract. Brain Research. 641: 198-202. PMID 8012821 DOI: 10.1016/0006-8993(94)90146-5  1
1994 Reith J, Benkelfat C, Sherwin A, Yasuhara Y, Kuwabara H, Andermann F, Bachneff S, Cumming P, Diksic M, Dyve SE, Etienne P, Evans AC, Lal S, Shevell M, Savard G, et al. Elevated dopa decarboxylase activity in living brain of patients with psychosis. Proceedings of the National Academy of Sciences of the United States of America. 91: 11651-4. PMID 7972118 DOI: 10.1073/pnas.91.24.11651  1
1994 Cumming P, Kuwabara H, Gjedde A. A kinetic analysis of 6-[18F]fluoro-L-dihydroxyphenylalanine metabolism in the rat. Journal of Neurochemistry. 63: 1675-82. PMID 7931323  1
1994 Cumming P, Venkatachalam TK, Rajagopal S, Diksic M, Gjedde A. Brain uptake of alpha-[14C]methyl-para-tyrosine in the rat. Synapse (New York, N.Y.). 17: 125-8. PMID 7916491 DOI: 10.1002/syn.890170208  1
1994 Cumming P, Laliberté C, Gjedde A. Distribution of histamine H3 binding in forebrain of mouse and guinea pig. Brain Research. 664: 276-9. PMID 7895042 DOI: 10.1016/0006-8993(94)91985-2  1
1993 Hoshi H, Kuwabara H, Léger G, Cumming P, Guttman M, Gjedde A. 6-[18F]fluoro-L-dopa metabolism in living human brain: a comparison of six analytical methods. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 13: 57-69. PMID 8417011 DOI: 10.1038/jcbfm.1993.8  1
1993 Cumming P, Vincent SR. Altered histamine H3 binding in rat forebrain after reserpine treatment. Brain Research. 602: 53-6. PMID 8383572 DOI: 10.1016/0006-8993(93)90240-N  1
1992 Cumming P, Vincent SR. Inhibition of histamine-N-methyltransferase (HNMT) by fragments of 9-amino-1,2,3,4-tetrahydroacridine (tacrine) and by beta-carbolines. Biochemical Pharmacology. 44: 989-92. PMID 1530666 DOI: 10.1016/0006-2952(92)90133-4  1
1992 Cumming P, Brown E, Damsma G, Fibiger H. Formation and clearance of interstitial metabolites of dopamine and serotonin in the rat striatum: an in vivo microdialysis study. Journal of Neurochemistry. 59: 1905-14. PMID 1383428 DOI: 10.1111/j.1471-4159.1992.tb11026.x  1
1991 Brown EE, Damsma G, Cumming P, Fibiger HC. Interstitial 3-methoxytyramine reflects striatal dopamine release: an in vivo microdialysis study. Journal of Neurochemistry. 57: 701-7. PMID 1906527 DOI: 10.1111/j.1471-4159.1991.tb03802.x  1
1991 Cumming P, Damsma G, Fibiger HC, Vincent SR. Characterization of extracellular histamine in the striatum and bed nucleus of the stria terminalis of the rat: an in vivo microdialysis study. Journal of Neurochemistry. 56: 1797-803. PMID 1707442  1
1991 Cumming P, Shaw C, Vincent SR. High affinity histamine binding site is the H3 receptor: characterization and autoradiographic localization in rat brain. Synapse (New York, N.Y.). 8: 144-51. PMID 1652795 DOI: 10.1002/syn.890080208  1
1990 Cumming P, Reiner PB, Vincent SR. Inhibition of rat brain histamine-N-methyltransferase by 9-amino-1,2,3,4-tetrahydroacridine (THA). Biochemical Pharmacology. 40: 1345-50. PMID 2403387 DOI: 10.1016/0006-2952(90)90402-7  1
1989 Cumming P, Jakubovic A, Vincent SR. Cerebral histamine levels are unaffected by MPTP administration in the mouse. European Journal of Pharmacology. 166: 299-301. PMID 2792195 DOI: 10.1016/0014-2999(89)90071-X  1
1988 Cumming P, Häusser M, Martin WR, Grierson J, Adam MJ, Ruth TJ, McGeer EG. Kinetics of in vitro decarboxylation and the in vivo metabolism of 2-18F- and 6-18F-fluorodopa in the hooded rat. Biochemical Pharmacology. 37: 247-50. PMID 3124856 DOI: 10.1016/0006-2952(88)90725-3  1
1987 Cumming P, Boyes BE, Martin WR, Adam M, Ruth TJ, McGeer EG. Altered metabolism of [18F]-6-fluorodopa in the hooded rat following inhibition of catechol-O-methyltransferase with U-0521. Biochemical Pharmacology. 36: 2527-31. PMID 3111485 DOI: 10.1016/0006-2952(87)90526-0  1
1987 Cumming P, Boyes BE, Martin WR, Adam M, Grierson J, Ruth T, McGeer EG. The metabolism of [18F]6-fluoro-L-3,4-dihydroxyphenylalanine in the hooded rat. Journal of Neurochemistry. 48: 601-8. PMID 3098920  1
1987 Cumming P, Kamo H, McGeer EG, McGeer PL. Toxicity of p-methoxyphenol to dopamine neurons in the rat substantia nigra. Neuropharmacology. 26: 1795-7. PMID 2893988  0.36
1987 Radke JM, Cumming P, Vincent SR. Effects of MPTP poisoning on central somatostatin and substance P levels in the mouse. European Journal of Pharmacology. 134: 105-8. PMID 2435563 DOI: 10.1016/0014-2999(87)90137-3  1
1986 Boyes BE, Cumming P, Martin WR, McGeer EG. Determination of plasma [18F]-6-fluorodopa during positron emission tomography: elimination and metabolism in carbidopa treated subjects. Life Sciences. 39: 2243-52. PMID 3097437 DOI: 10.1016/0024-3205(86)90403-0  1
1986 Cumming P, Von Krosigk M, Reiner PB, McGeer EG, Vincent SR. Absence of adrenaline neurons in the guinea pig brain: a combined immunohistochemical and high-performance liquid chromatography study. Neuroscience Letters. 63: 125-30. PMID 2869455 DOI: 10.1016/0304-3940(86)90048-0  1
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