Marek Mlodzik - Publications

Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Developmental genetics/drosophila retina/planar polarity

145 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Koca Y, Housden BE, Gault WJ, Bray SJ, Mlodzik M. Notch signaling coordinates ommatidial rotation in the Drosophila eye via transcriptional regulation of the EGF-Receptor ligand Argos. Scientific Reports. 9: 18628. PMID 31819141 DOI: 10.1038/S41598-019-55203-W  0.36
2019 Domingos PM, Jenny A, Combie KF, Del Alamo D, Mlodzik M, Steller H, Mollereau B. Regulation of Numb during planar cell polarity establishment in the Drosophila eye. Mechanisms of Development. 103583. PMID 31678471 DOI: 10.1016/J.Mod.2019.103583  0.56
2018 Collu GM, Jenny A, Gaengel K, Mirkovic I, Chin ML, Weber U, Smith MJ, Mlodzik M. Prickle is phosphorylated by Nemo and targeted for degradation to maintain Prickle/Spiny-legs isoform balance during planar cell polarity establishment. Plos Genetics. 14: e1007391. PMID 29758044 DOI: 10.1371/Journal.Pgen.1007391  0.56
2016 Carvajal-Gonzalez JM, Roman AC, Mlodzik M. Positioning of centrioles is a conserved readout of Frizzled planar cell polarity signalling. Nature Communications. 7: 11135. PMID 27021213 DOI: 10.1038/ncomms11135  1
2015 Yang Y, Mlodzik M. Wnt-Frizzled/Planar Cell Polarity Signaling: Cellular Orientation by Facing the Wind (Wnt). Annual Review of Cell and Developmental Biology. 31: 623-646. PMID 26566118 DOI: 10.1146/Annurev-Cellbio-100814-125315  1
2015 Collu GM, Mlodzik M. Planar polarity: converting a morphogen gradient into cellular polarity. Current Biology : Cb. 25: R372-4. PMID 25942551 DOI: 10.1016/j.cub.2015.03.011  1
2015 Carvajal-Gonzalez JM, Balmer S, Mendoza M, Dussert A, Collu G, Roman AC, Weber U, Ciruna B, Mlodzik M. The clathrin adaptor AP-1 complex and Arf1 regulate planar cell polarity in vivo. Nature Communications. 6: 6751. PMID 25849195 DOI: 10.1038/Ncomms7751  1
2015 Mlodzik M. The Dishevelled Protein Family: Still Rather a Mystery After Over 20 Years of Molecular Studies Current Topics in Developmental Biology. DOI: 10.1016/bs.ctdb.2015.11.027  1
2014 Carvajal-Gonzalez JM, Mlodzik M. Mechanisms of planar cell polarity establishment in Drosophila. F1000prime Reports. 6: 98. PMID 25580252 DOI: 10.12703/P6-98  1
2014 Mlodzik M, Halder G. Walter J. Gehring (1939-2014). Developmental Biology. 395: 1-3. PMID 25419555 DOI: 10.1016/J.Ydbio.2014.09.007  1
2014 Mlodzik M, Halder G. Walter J Gehring (1939-2014). The Embo Journal. 33: 1615-6. PMID 25006173 DOI: 10.15252/embj.201489291  1
2014 Weber U, Rodriguez E, Martignetti J, Mlodzik M. Luna, a Drosophila KLF6/KLF7, is maternally required for synchronized nuclear and centrosome cycles in the preblastoderm embryo. Plos One. 9: e96933. PMID 24915236 DOI: 10.1371/Journal.Pone.0096933  1
2014 Serysheva E, Mlodzik M, Jenny A. WNKs in Wnt/β-catenin signaling. Cell Cycle (Georgetown, Tex.). 13: 173-4. PMID 24241206 DOI: 10.4161/Cc.27038  1
2014 Balmer S, Dussert A, Collu GM, Benitez E, Iomini C, Mlodzik M. Components of Intraflagellar Transport Complex A Function Independently of the Cilium to Regulate Canonical Wnt Signaling in Drosophila Developmental Cell. DOI: 10.1016/j.devcel.2015.07.016  1
2013 Chin ML, Mlodzik M. The Drosophila selectin furrowed mediates intercellular planar cell polarity interactions via frizzled stabilization. Developmental Cell. 26: 455-68. PMID 23973164 DOI: 10.1016/j.devcel.2013.07.006  1
2013 Grumolato L, Liu G, Haremaki T, Mungamuri SK, Mong P, Akiri G, Lopez-Bergami P, Arita A, Anouar Y, Mlodzik M, Ronai ZA, Brody J, Weinstein DC, Aaronson SA. β-Catenin-independent activation of TCF1/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors. Plos Genetics. 9: e1003603. PMID 23966864 DOI: 10.1371/Journal.Pgen.1003603  1
2013 Wu J, Roman AC, Carvajal-Gonzalez JM, Mlodzik M. Wg and Wnt4 provide long-range directional input to planar cell polarity orientation in Drosophila. Nature Cell Biology. 15: 1045-55. PMID 23912125 DOI: 10.1038/ncb2806  1
2013 Serysheva E, Berhane H, Grumolato L, Demir K, Balmer S, Bodak M, Boutros M, Aaronson S, Mlodzik M, Jenny A. Wnk kinases are positive regulators of canonical Wnt/β-catenin signalling. Embo Reports. 14: 718-25. PMID 23797875 DOI: 10.1038/Embor.2013.136  1
2013 Muñoz-Soriano V, Ruiz C, Pérez-Alonso M, Mlodzik M, Paricio N. Nemo regulates cell dynamics and represses the expression of miple, a midkine/pleiotrophin cytokine, during ommatidial rotation. Developmental Biology. 377: 113-25. PMID 23428616 DOI: 10.1016/j.ydbio.2013.02.006  1
2012 Singh J, Mlodzik M. Planar cell polarity signaling: coordination of cellular orientation across tissues. Wiley Interdisciplinary Reviews. Developmental Biology. 1: 479-99. PMID 23066429 DOI: 10.1002/Wdev.32  1
2012 Singh J, Mlodzik M. Hibris, a Drosophila nephrin homolog, is required for presenilin-mediated Notch and APP-like cleavages. Developmental Cell. 23: 82-96. PMID 22814602 DOI: 10.1016/J.Devcel.2012.04.021  1
2012 Weber U, Gault WJ, Olguin P, Serysheva E, Mlodzik M. Novel regulators of planar cell polarity: a genetic analysis in Drosophila. Genetics. 191: 145-62. PMID 22391484 DOI: 10.1534/Genetics.111.137190  1
2012 Gault WJ, Olguin P, Weber U, Mlodzik M. Drosophila CK1-γ, gilgamesh, controls PCP-mediated morphogenesis through regulation of vesicle trafficking. The Journal of Cell Biology. 196: 605-21. PMID 22391037 DOI: 10.1083/Jcb.201107137  1
2012 Wong JS, Iorns E, Rheault MN, Ward TM, Rashmi P, Weber U, Lippman ME, Faul C, Mlodzik M, Mundel P. Rescue of tropomyosin deficiency in Drosophila and human cancer cells by synaptopodin reveals a role of tropomyosin α in RhoA stabilization. The Embo Journal. 31: 1028-40. PMID 22157816 DOI: 10.1038/Emboj.2011.464  1
2011 Yanfeng WA, Berhane H, Mola M, Singh J, Jenny A, Mlodzik M. Functional dissection of phosphorylation of Disheveled in Drosophila. Developmental Biology. 360: 132-42. PMID 21963539 DOI: 10.1016/J.Ydbio.2011.09.017  1
2011 Mirkovic I, Gault WJ, Rahnama M, Jenny A, Gaengel K, Bessette D, Gottardi CJ, Verheyen EM, Mlodzik M. Nemo kinase phosphorylates β-catenin to promote ommatidial rotation and connects core PCP factors to E-cadherin-β-catenin. Nature Structural & Molecular Biology. 18: 665-72. PMID 21552260 DOI: 10.1038/Nsmb.2049  1
2011 Grumolato L, Weber U, Mlodzik M. A new piece to the unsolved planar cell polarity puzzle. Developmental Cell. 20: 146-7. PMID 21316583 DOI: 10.1016/j.devcel.2011.01.013  1
2011 Blitzer AL, Panagis L, Gusella GL, Danias J, Mlodzik M, Iomini C. Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium. Proceedings of the National Academy of Sciences of the United States of America. 108: 2819-24. PMID 21285373 DOI: 10.1073/Pnas.1016702108  1
2011 Olguín P, Glavic A, Mlodzik M. Intertissue mechanical stress affects Frizzled-mediated planar cell polarity in the Drosophila notum epidermis. Current Biology : Cb. 21: 236-42. PMID 21276726 DOI: 10.1016/j.cub.2011.01.001  1
2010 Song JK, Kannan R, Merdes G, Singh J, Mlodzik M, Giniger E. Disabled is a bona fide component of the Abl signaling network. Development (Cambridge, England). 137: 3719-27. PMID 20940230 DOI: 10.1242/Jcs.082412  1
2010 Singh J, Yanfeng WA, Grumolato L, Aaronson SA, Mlodzik M. Abelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylation. Genes & Development. 24: 2157-68. PMID 20837657 DOI: 10.1101/Gad.1961010  1
2010 Olguin P, Mlodzik M. A new spin on planar cell polarity. Cell. 142: 674-6. PMID 20813254 DOI: 10.1016/j.cell.2010.08.025  1
2010 Djiane A, Mlodzik M. The Drosophila GIPC homologue can modulate myosin based processes and planar cell polarity but is not essential for development. Plos One. 5: e11228. PMID 20574526 DOI: 10.1371/journal.pone.0011228  1
2010 Singh J, Aaronson SA, Mlodzik M. Drosophila Abelson kinase mediates cell invasion and proliferation through two distinct MAPK pathways. Oncogene. 29: 4033-45. PMID 20453880 DOI: 10.1038/Onc.2010.155  1
2009 Itoh K, Jenny A, Mlodzik M, Sokol SY. Centrosomal localization of Diversin and its relevance to Wnt signaling. Journal of Cell Science. 122: 3791-8. PMID 19789178 DOI: 10.1242/Jcs.057067  1
2009 Courbard JR, Djiane A, Wu J, Mlodzik M. The apical/basal-polarity determinant Scribble cooperates with the PCP core factor Stbm/Vang and functions as one of its effectors. Developmental Biology. 333: 67-77. PMID 19563796 DOI: 10.1016/j.ydbio.2009.06.024  1
2009 Wu J, Mlodzik M. A quest for the mechanism regulating global planar cell polarity of tissues. Trends in Cell Biology. 19: 295-305. PMID 19560358 DOI: 10.1016/j.tcb.2009.04.003  1
2009 Skouloudaki K, Puetz M, Simons M, Courbard JR, Boehlke C, Hartleben B, Engel C, Moeller MJ, Englert C, Bollig F, Schäfer T, Ramachandran H, Mlodzik M, Huber TB, Kuehn EW, et al. Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development. Proceedings of the National Academy of Sciences of the United States of America. 106: 8579-84. PMID 19439659 DOI: 10.1073/pnas.0811691106  1
2009 Mlodzik M. Ubiquitin connects with planar cell polarity. Cell. 137: 209-11. PMID 19379687 DOI: 10.1016/j.cell.2009.04.002  1
2009 Simons M, Gault WJ, Gotthardt D, Rohatgi R, Klein TJ, Shao Y, Lee HJ, Wu AL, Fang Y, Satlin LM, Dow JT, Chen J, Zheng J, Boutros M, Mlodzik M. Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization. Nature Cell Biology. 11: 286-94. PMID 19234454 DOI: 10.1038/Ncb1836  1
2009 Oishi K, Zhang H, Gault WJ, Wang CJ, Tan CC, Kim IK, Ying H, Rahman T, Pica N, Tartaglia M, Mlodzik M, Gelb BD. Phosphatase-defective LEOPARD syndrome mutations in PTPN11 gene have gain-of-function effects during Drosophila development. Human Molecular Genetics. 18: 193-201. PMID 18849586 DOI: 10.1093/Hmg/Ddn336  1
2008 Wu J, Mlodzik M. The frizzled extracellular domain is a ligand for Van Gogh/Stbm during nonautonomous planar cell polarity signaling. Developmental Cell. 15: 462-9. PMID 18804440 DOI: 10.1016/j.devcel.2008.08.004  1
2008 Simons M, Mlodzik M. Planar cell polarity signaling: from fly development to human disease. Annual Review of Genetics. 42: 517-40. PMID 18710302 DOI: 10.1146/annurev.genet.42.110807.091432  1
2008 del Alamo D, Mlodzik M. Self-modulation of Notch signaling during ommatidial development via the Roughened eye transcriptional repressor. Development (Cambridge, England). 135: 2895-904. PMID 18653560 DOI: 10.1242/dev.022194  1
2008 Gaengel K, Mlodzik M. Microscopic analysis of the adult Drosophila retina using semithin plastic sections. Methods in Molecular Biology (Clifton, N.J.). 420: 277-87. PMID 18641954 DOI: 10.1007/978-1-59745-583-1_17  1
2008 Jenny A, Mlodzik M. Modified vectors for the two-step directional cloning of inverted repeats for RNA interference in Drosophila. Biotechniques. 44: 335-9. PMID 18361787 DOI: 10.2144/000112720  1
2008 Weber U, Pataki C, Mihaly J, Mlodzik M. Combinatorial signaling by the Frizzled/PCP and Egfr pathways during planar cell polarity establishment in the Drosophila eye. Developmental Biology. 316: 110-23. PMID 18291359 DOI: 10.1016/j.ydbio.2008.01.016  1
2008 Wu J, Jenny A, Mirkovic I, Mlodzik M. Frizzled-Dishevelled signaling specificity outcome can be modulated by Diego in Drosophila. Mechanisms of Development. 125: 30-42. PMID 18065209 DOI: 10.1016/J.Mod.2007.10.006  1
2007 Montrasio S, Mlodzik M, Fanto M. A new allele uncovers the role of echinus in the control of ommatidial rotation in the Drosophila eye. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 236: 2936-42. PMID 17879315 DOI: 10.1002/dvdy.21328  1
2007 Muñoz-Descalzo S, Gómez-Cabrero A, Mlodzik M, Paricio N. Analysis of the role of the Rac/Cdc42 GTPases during planar cell polarity generation in Drosophila. The International Journal of Developmental Biology. 51: 379-87. PMID 17616927 DOI: 10.1387/ijdb.062250sm  1
2007 Curtiss J, Burnett M, Mlodzik M. distal antenna and distal antenna-related function in the retinal determination network during eye development in Drosophila. Developmental Biology. 306: 685-702. PMID 17493605 DOI: 10.1016/j.ydbio.2007.04.006  1
2007 Seifert JR, Mlodzik M. Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility. Nature Reviews. Genetics. 8: 126-38. PMID 17230199 DOI: 10.1038/nrg2042  1
2006 Delaney JR, Mlodzik M. TGF-beta activated kinase-1: new insights into the diverse roles of TAK1 in development and immunity. Cell Cycle (Georgetown, Tex.). 5: 2852-5. PMID 17218788 DOI: 10.4161/Cc.5.24.3558  1
2006 del Alamo D, Mlodzik M. Frizzled/PCP-dependent asymmetric neuralized expression determines R3/R4 fates in the Drosophila eye. Developmental Cell. 11: 887-94. PMID 17141162 DOI: 10.1016/j.devcel.2006.09.016  1
2006 Moeller H, Jenny A, Schaeffer HJ, Schwarz-Romond T, Mlodzik M, Hammerschmidt M, Birchmeier W. Diversin regulates heart formation and gastrulation movements in development. Proceedings of the National Academy of Sciences of the United States of America. 103: 15900-5. PMID 17032765 DOI: 10.1073/Pnas.0603808103  1
2006 Jenny A, Mlodzik M. Planar cell polarity signaling: a common mechanism for cellular polarization. The Mount Sinai Journal of Medicine, New York. 73: 738-50. PMID 17008934  1
2006 Mirkovic I, Mlodzik M. Cooperative activities of drosophila DE-cadherin and DN-cadherin regulate the cell motility process of ommatidial rotation. Development (Cambridge, England). 133: 3283-93. PMID 16887833 DOI: 10.1242/Dev.02468  1
2006 Mlodzik M. A GAP in convergent extension scores PAR. Developmental Cell. 11: 2-4. PMID 16824946 DOI: 10.1016/j.devcel.2006.06.010  1
2006 Klein TJ, Jenny A, Djiane A, Mlodzik M. CKIepsilon/discs overgrown promotes both Wnt-Fz/beta-catenin and Fz/PCP signaling in Drosophila. Current Biology : Cb. 16: 1337-43. PMID 16824922 DOI: 10.1016/J.Cub.2006.06.030  1
2006 Delaney JR, Stöven S, Uvell H, Anderson KV, Engström Y, Mlodzik M. Cooperative control of Drosophila immune responses by the JNK and NF-kappaB signaling pathways. The Embo Journal. 25: 3068-77. PMID 16763552 DOI: 10.1038/sj.emboj.7601182  1
2006 Matusek T, Djiane A, Jankovics F, Brunner D, Mlodzik M, Mihály J. The Drosophila formin DAAM regulates the tracheal cuticle pattern through organizing the actin cytoskeleton. Development (Cambridge, England). 133: 957-66. PMID 16469972 DOI: 10.1242/Dev.02266  1
2006 Ciruna B, Jenny A, Lee D, Mlodzik M, Schier AF. Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature. 439: 220-4. PMID 16407953 DOI: 10.1038/Nature04375  1
2006 Oishi K, Gaengel K, Krishnamoorthy S, Kamiya K, Kim IK, Ying H, Weber U, Perkins LA, Tartaglia M, Mlodzik M, Pick L, Gelb BD. Transgenic Drosophila models of Noonan syndrome causing PTPN11 gain-of-function mutations. Human Molecular Genetics. 15: 543-53. PMID 16399795 DOI: 10.1093/Hmg/Ddi471  1
2005 Dollar GL, Weber U, Mlodzik M, Sokol SY. Regulation of Lethal giant larvae by Dishevelled. Nature. 437: 1376-80. PMID 16251968 DOI: 10.1038/nature04116  1
2005 Klein TJ, Mlodzik M. Planar cell polarization: an emerging model points in the right direction. Annual Review of Cell and Developmental Biology. 21: 155-76. PMID 16212491 DOI: 10.1146/Annurev.Cellbio.21.012704.132806  1
2005 Reynolds-Kenneally J, Mlodzik M. Notch signaling controls proliferation through cell-autonomous and non-autonomous mechanisms in the Drosophila eye. Developmental Biology. 285: 38-48. PMID 16039641 DOI: 10.1016/J.Ydbio.2005.05.038  1
2005 Jenny A, Reynolds-Kenneally J, Das G, Burnett M, Mlodzik M. Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding. Nature Cell Biology. 7: 691-7. PMID 15937478 DOI: 10.1038/Ncb1271  1
2005 Djiane A, Yogev S, Mlodzik M. The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye. Cell. 121: 621-31. PMID 15907474 DOI: 10.1016/j.cell.2005.03.014  1
2005 Simons M, Gloy J, Ganner A, Bullerkotte A, Bashkurov M, Krönig C, Schermer B, Benzing T, Cabello OA, Jenny A, Mlodzik M, Polok B, Driever W, Obara T, Walz G. Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nature Genetics. 37: 537-43. PMID 15852005 DOI: 10.1038/Ng1552  1
2005 Mlodzik M. Planar cell polarity in the Drosophila eye: Cell fate and organization Advances in Developmental Biology. 14: 15-38. DOI: 10.1016/S1574-3349(05)14002-2  1
2004 Domingos PM, Mlodzik M, Mendes CS, Brown S, Steller H, Mollereau B. Spalt transcription factors are required for R3/R4 specification and establishment of planar cell polarity in the Drosophila eye. Development (Cambridge, England). 131: 5695-702. PMID 15509769 DOI: 10.1242/Dev.01443  1
2004 Das G, Jenny A, Klein TJ, Eaton S, Mlodzik M. Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes. Development (Cambridge, England). 131: 4467-76. PMID 15306567 DOI: 10.1242/Dev.01317  1
2004 Wu J, Klein TJ, Mlodzik M. Subcellular localization of frizzled receptors, mediated by their cytoplasmic tails, regulates signaling pathway specificity. Plos Biology. 2: E158. PMID 15252441 DOI: 10.1371/Journal.Pbio.0020158  1
2004 Klein TJ, Mlodzik M. A conserved signaling cassette regulates hair patterning from Drosophila to man. Proceedings of the National Academy of Sciences of the United States of America. 101: 9173-4. PMID 15199187 DOI: 10.1073/Pnas.0403301101  1
2003 Wong HC, Bourdelas A, Krauss A, Lee HJ, Shao Y, Wu D, Mlodzik M, Shi DL, Zheng J. Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled. Molecular Cell. 12: 1251-60. PMID 14636582 DOI: 10.1016/S1097-2765(03)00427-1  1
2003 Weber U, Eroglu C, Mlodzik M. Phospholipid membrane composition affects EGF receptor and Notch signaling through effects on endocytosis during Drosophila development. Developmental Cell. 5: 559-70. PMID 14536058 DOI: 10.1016/S1534-5807(03)00273-9  1
2003 De Graeve F, Smaldone S, Laub F, Mlodzik M, Bhat M, Ramirez F. Identification of the Drosophila progenitor of mammalian Krüppel-like factors 6 and 7 and a determinant of fly development. Gene. 314: 55-62. PMID 14527717 DOI: 10.1016/S0378-1119(03)00720-0  1
2003 Gaengel K, Mlodzik M. Egfr signaling regulates ommatidial rotation and cell motility in the Drosophila eye via MAPK/Pnt signaling and the Ras effector Canoe/AF6. Development (Cambridge, England). 130: 5413-23. PMID 14507782 DOI: 10.1242/dev.00759  1
2003 Kenyon KL, Ranade SS, Curtiss J, Mlodzik M, Pignoni F. Coordinating proliferation and tissue specification to promote regional identity in the Drosophila head. Developmental Cell. 5: 403-14. PMID 12967560 DOI: 10.1016/S1534-5807(03)00243-0  1
2003 Jenny A, Darken RS, Wilson PA, Mlodzik M. Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling. The Embo Journal. 22: 4409-20. PMID 12941693 DOI: 10.1093/Emboj/Cdg424  1
2003 Emerald BS, Curtiss J, Mlodzik M, Cohen SM. Distal antenna and distal antenna related encode nuclear proteins containing pipsqueak motifs involved in antenna development in Drosophila. Development (Cambridge, England). 130: 1171-80. PMID 12571108 DOI: 10.1242/dev.00323  1
2002 Mlodzik M. Tissue polarity in the retina. Results and Problems in Cell Differentiation. 37: 89-106. PMID 25707071 DOI: 10.1007/978-3-540-45398-7_7  1
2002 Mlodzik M. Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation? Trends in Genetics : Tig. 18: 564-71. PMID 12414186 DOI: 10.1016/S0168-9525(02)02770-1  1
2002 Das G, Reynolds-Kenneally J, Mlodzik M. The atypical cadherin Flamingo links Frizzled and Notch signaling in planar polarity establishment in the Drosophila eye. Developmental Cell. 2: 655-66. PMID 12015972 DOI: 10.1016/S1534-5807(02)00147-8  1
2002 Curtiss J, Halder G, Mlodzik M. Selector and signalling molecules cooperate in organ patterning. Nature Cell Biology. 4: E48-51. PMID 11875444 DOI: 10.1038/ncb0302-e48  1
2002 Darken RS, Scola AM, Rakeman AS, Das G, Mlodzik M, Wilson PA. The planar polarity gene strabismus regulates convergent extension movements in Xenopus. The Embo Journal. 21: 976-85. PMID 11867525 DOI: 10.1093/emboj/21.5.976  1
2001 Feiguin F, Hannus M, Mlodzik M, Eaton S. The ankyrin repeat protein Diego mediates Frizzled-dependent planar polarization. Developmental Cell. 1: 93-101. PMID 11703927 DOI: 10.1016/S1534-5807(01)00010-7  1
2001 Ciapponi L, Jackson DB, Mlodzik M, Bohmann D. Drosophila Fos mediates ERK and JNK signals via distinct phosphorylation sites. Genes & Development. 15: 1540-53. PMID 11410534 DOI: 10.1101/Gad.886301  1
2001 Mihaly J, Kockel L, Gaengel K, Weber U, Bohmann D, Mlodzik M. The role of the Drosophila TAK homologue dTAK during development. Mechanisms of Development. 102: 67-79. PMID 11287182 DOI: 10.1016/S0925-4773(01)00285-4  1
2000 Fanto M, Weber U, Strutt DI, Mlodzik M. Nuclear signaling by Rac and Rho GTPases is required in the establishment of epithelial planar polarity in the Drosophila eye. Current Biology : Cb. 10: 979-88. PMID 10985385 DOI: 10.1016/S0960-9822(00)00645-X  1
2000 Weber U, Paricio N, Mlodzik M. Jun mediates Frizzled-induced R3/R4 cell fate distinction and planar polarity determination in the Drosophila eye. Development (Cambridge, England). 127: 3619-29. PMID 10903185  1
2000 Boutros M, Mihaly J, Bouwmeester T, Mlodzik M. Signaling specificity by Frizzled receptors in Drosophila. Science (New York, N.Y.). 288: 1825-8. PMID 10846164 DOI: 10.1126/science.288.5472.1825  1
2000 Blaumueller CM, Mlodzik M. The Drosophila tumor suppressor expanded regulates growth, apoptosis, and patterning during development. Mechanisms of Development. 92: 251-62. PMID 10727863 DOI: 10.1016/S0925-4773(00)00246-X  1
2000 Pazman C, Mayes CA, Fanto M, Haynes SR, Mlodzik M. Rasputin, the Drosophila homologue of the RasGAP SH3 binding protein, functions in ras- and Rho-mediated signaling. Development (Cambridge, England). 127: 1715-25. PMID 10725247  1
2000 Mlodzik M. Spiny legs and prickled bodies: new insights and complexities in planar polarity establishment. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 22: 311-5. PMID 10723028 DOI: 10.1002/(SICI)1521-1878(200004)22:4<311::AID-BIES1>3.0.CO;2-J  1
2000 Curtiss J, Mlodzik M. Morphogenetic furrow initiation and progression during eye development in Drosophila: the roles of decapentaplegic, hedgehog and eyes absent. Development (Cambridge, England). 127: 1325-36. PMID 10683184  1
1999 Goberdhan DC, Paricio N, Goodman EC, Mlodzik M, Wilson C. Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway. Genes & Development. 13: 3244-58. PMID 10617573 DOI: 10.1101/gad.13.24.3244  1
1999 Mlodzik M. Planar polarity in the Drosophila eye: a multifaceted view of signaling specificity and cross-talk. The Embo Journal. 18: 6873-9. PMID 10601009 DOI: 10.1093/emboj/18.24.6873  1
1999 Valcárcel R, Weber U, Jackson DB, Benes V, Ansorge W, Bohmann D, Mlodzik M. Sec61beta, a subunit of the protein translocation channel, is required during Drosophila development. Journal of Cell Science. 112: 4389-96. PMID 10564656  1
1999 Boutros M, Mlodzik M. Dishevelled: at the crossroads of divergent intracellular signaling pathways. Mechanisms of Development. 83: 27-37. PMID 10507837 DOI: 10.1016/S0925-4773(99)00046-5  1
1999 Luo H, Asha H, Kockel L, Parke T, Mlodzik M, Dearolf CR. The Drosophila Jak kinase hopscotch is required for multiple developmental processes in the eye. Developmental Biology. 213: 432-41. PMID 10479459 DOI: 10.1006/dbio.1999.9390  1
1999 Paricio N, Feiguin F, Boutros M, Eaton S, Mlodzik M. The Drosophila STE20-like kinase misshapen is required downstream of the Frizzled receptor in planar polarity signaling. The Embo Journal. 18: 4669-78. PMID 10469646 DOI: 10.1093/emboj/18.17.4669  1
1999 Seo HC, Curtiss J, Mlodzik M, Fjose A. Six class homeobox genes in drosophila belong to three distinct families and are involved in head development. Mechanisms of Development. 83: 127-39. PMID 10381573 DOI: 10.1016/S0925-4773(99)00045-3  1
1999 Fanto M, Mlodzik M. Asymmetric Notch activation specifies photoreceptors R3 and R4 and planar polarity in the Drosophila eye. Nature. 397: 523-6. PMID 10028968 DOI: 10.1038/17389  1
1999 Valcárcel R, Weber U, Jackson DB, Benes V, Ansorge W, Bohmann D, Mlodzik M. Sec61β, a subunit of the protein translocation channel, is required during Drosophila development Journal of Cell Science. 112: 4389-4396.  1
1998 Lee EC, Yu SY, Hu X, Mlodzik M, Baker NE. Functional analysis of the fibrinogen-related scabrous gene from Drosophila melanogaster identifies potential effector and stimulatory protein domains. Genetics. 150: 663-73. PMID 9755198  1
1998 Boutros M, Paricio N, Strutt DI, Mlodzik M. Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling. Cell. 94: 109-18. PMID 9674432 DOI: 10.1016/S0092-8674(00)81226-X  1
1998 Fanto M, Mayes CA, Mlodzik M. Linking cell-fate specification to planar polarity: determination of the R3/R4 photoreceptors is a prerequisite for the interpretation of the Frizzled mediated polarity signal. Mechanisms of Development. 74: 51-8. PMID 9651479 DOI: 10.1016/S0925-4773(98)00063-X  1
1998 Artero R, Prokop A, Paricio N, Begemann G, Pueyo I, Mlodzik M, Perez-Alonso M, Baylies MK. The muscleblind gene participates in the organization of Z-bands and epidermal attachments of Drosophila muscles and is regulated by Dmef2. Developmental Biology. 195: 131-43. PMID 9520330 DOI: 10.1006/Dbio.1997.8833  1
1997 Isaksson A, Peverali FA, Kockel L, Mlodzik M, Bohmann D. The deubiquitination enzyme fat facets negatively regulates RTK/Ras/MAPK signalling during Drosophila eye development. Mechanisms of Development. 68: 59-67. PMID 9431804 DOI: 10.1016/S0925-4773(97)00126-3  1
1997 Zeitlinger J, Kockel L, Peverali FA, Jackson DB, Mlodzik M, Bohmann D. Defective dorsal closure and loss of epidermal decapentaplegic expression in Drosophila fos mutants. The Embo Journal. 16: 7393-401. PMID 9405368 DOI: 10.1093/Emboj/16.24.7393  1
1997 Zeidler MP, Mlodzik M. six-banded, a novel Drosophila gene, is expressed in 6 segmental stripes during embryonic development and in the eye imaginal disc. Biological Chemistry. 378: 1119-24. PMID 9372180 DOI: 10.1515/Bchm.1997.378.10.1119  1
1997 Begemann G, Paricio N, Artero R, Kiss I, Pérez-Alonso M, Mlodzik M. muscleblind, a gene required for photoreceptor differentiation in Drosophila, encodes novel nuclear Cys3His-type zinc-finger-containing proteins. Development (Cambridge, England). 124: 4321-31. PMID 9334280  1
1997 Strutt DI, Mlodzik M. Hedgehog is an indirect regulator of morphogenetic furrow progression in the Drosophila eye disc. Development (Cambridge, England). 124: 3233-40. PMID 9310318  1
1997 Kockel L, Zeitlinger J, Staszewski LM, Mlodzik M, Bohmann D. Jun in Drosophila development: redundant and nonredundant functions and regulation by two MAPK signal transduction pathways. Genes & Development. 11: 1748-58. PMID 9224723 DOI: 10.1101/Gad.11.13.1748  1
1997 Kockel L, Vorbrüggen G, Jäckle H, Mlodzik M, Bohmann D. Requirement for Drosophila 14-3-3 zeta in Raf-dependent photoreceptor development. Genes & Development. 11: 1140-7. PMID 9159395 DOI: 10.1101/Gad.11.9.1140  1
1997 Strutt DI, Weber U, Mlodzik M. The role of RhoA in tissue polarity and Frizzled signalling. Nature. 387: 292-5. PMID 9153394 DOI: 10.1038/387292a0  1
1997 Yuan YP, Schultz J, Mlodzik M, Bork P. Secreted fringe-like signaling molecules may be glycosyltransferases. Cell. 88: 9-11. PMID 9019410 DOI: 10.1016/S0092-8674(00)81852-8  1
1996 Strutt DI, Mlodzik M. The regulation of hedgehog and decapentaplegic during Drosophila eye imaginal disc development. Mechanisms of Development. 58: 39-50. PMID 8887315 DOI: 10.1016/S0925-4773(96)00555-2  1
1996 Derynck R, Gelbart WM, Harland RM, Heldin CH, Kern SE, Massagué J, Melton DA, Mlodzik M, Padgett RW, Roberts AB, Smith J, Thomsen GH, Vogelstein B, Wang XF. Nomenclature: vertebrate mediators of TGFbeta family signals. Cell. 87: 173. PMID 8861901 DOI: 10.1016/S0092-8674(00)81335-5  1
1996 Wiersdorff V, Lecuit T, Cohen SM, Mlodzik M. Mad acts downstream of Dpp receptors, revealing a differential requirement for dpp signaling in initiation and propagation of morphogenesis in the Drosophila eye. Development (Cambridge, England). 122: 2153-62. PMID 8681796  1
1996 Peverali FA, Isaksson A, Papavassiliou AG, Plastina P, Staszewski LM, Mlodzik M, Bohmann D. Phosphorylation of Drosophila Jun by the MAP kinase rolled regulates photoreceptor differentiation. The Embo Journal. 15: 3943-50. PMID 8670899 DOI: 10.1002/J.1460-2075.1996.Tb00768.X  1
1996 Zeidler MP, Yokomori K, Tjian R, Mlodzik M. Drosophila TFIIA-S is up-regulated and required during Ras-mediated photoreceptor determination. Genes & Development. 10: 50-9. PMID 8557194 DOI: 10.1101/Gad.10.1.50  1
1995 Strutt DI, Mlodzik M. Ommatidial polarity in the Drosophila eye is determined by the direction of furrow progression and local interactions. Development (Cambridge, England). 121: 4247-56. PMID 8575324  1
1995 Rogge R, Green PJ, Urano J, Horn-Saban S, Mlodzik M, Shilo BZ, Hartenstein V, Banerjee U. The role of yan in mediating the choice between cell division and differentiation. Development (Cambridge, England). 121: 3947-58. PMID 8575295  1
1995 Weber U, Siegel V, Mlodzik M. pipsqueak encodes a novel nuclear protein required downstream of seven-up for the development of photoreceptors R3 and R4. The Embo Journal. 14: 6247-57. PMID 8557044 DOI: 10.1002/J.1460-2075.1995.Tb00315.X  1
1995 Fjose A, Weber U, Mlodzik M. A novel vertebrate svp-related nuclear receptor is expressed as a step gradient in developing rhombomeres and is affected by retinoic acid. Mechanisms of Development. 52: 233-46. PMID 8541212 DOI: 10.1016/0925-4773(95)00404-O  1
1995 Treier M, Bohmann D, Mlodzik M. JUN cooperates with the ETS domain protein pointed to induce photoreceptor R7 fate in the Drosophila eye. Cell. 83: 753-60. PMID 8521492 DOI: 10.1016/0092-8674(95)90188-4  1
1995 Begemann G, Michon AM, vd Voorn L, Wepf R, Mlodzik M. The Drosophila orphan nuclear receptor seven-up requires the Ras pathway for its function in photoreceptor determination. Development (Cambridge, England). 121: 225-35. PMID 7867504  1
1995 Strutt DI, Wiersdorff V, Mlodzik M. Regulation of furrow progression in the Drosophila eye by cAMP-dependent protein kinase A. Nature. 373: 705-9. PMID 7854454 DOI: 10.1038/373705a0  1
1994 Yokomori K, Zeidler MP, Chen JL, Verrijzer CP, Mlodzik M, Tjian R. Drosophila TFIIA directs cooperative DNA binding with TBP and mediates transcriptional activation. Genes & Development. 8: 2313-23. PMID 7958898 DOI: 10.1101/Gad.8.19.2313  1
1994 Ellis MC, Weber U, Wiersdorff V, Mlodzik M. Confrontation of scabrous expressing and non-expressing cells is essential for normal ommatidial spacing in the Drosophila eye. Development (Cambridge, England). 120: 1959-69. PMID 7925001  1
1994 Bohmann D, Ellis MC, Staszewski LM, Mlodzik M. Drosophila Jun mediates Ras-dependent photoreceptor determination. Cell. 78: 973-86. PMID 7923366 DOI: 10.1016/0092-8674(94)90273-9  1
1993 Fjose A, Nornes S, Weber U, Mlodzik M. Functional conservation of vertebrate seven-up related genes in neurogenesis and eye development. The Embo Journal. 12: 1403-14. PMID 8467797 DOI: 10.1002/J.1460-2075.1993.Tb05784.X  1
1993 Hiromi Y, Mlodzik M, West SR, Rubin GM, Goodman CS. Ectopic expression of seven-up causes cell fate changes during ommatidial assembly. Development (Cambridge, England). 118: 1123-35. PMID 8269843  1
1992 Mlodzik M, Hiromi Y, Goodman CS, Rubin GM. The presumptive R7 cell of the developing Drosophila eye receives positional information independent of sevenless, boss and sina. Mechanisms of Development. 37: 37-42. PMID 1606018 DOI: 10.1016/0925-4773(92)90013-A  1
1992 Mlodzik M, Hiromi Y. Enhancer Trap Method in Drosophila: Its Application to Neurobiology Methods in Neurosciences. 9: 397-414. DOI: 10.1016/B978-0-12-185267-2.50030-1  0.4
1991 Heberlein U, Mlodzik M, Rubin GM. Cell-fate determination in the developing Drosophila eye: role of the rough gene. Development (Cambridge, England). 112: 703-12. PMID 1682125  1
1990 Baker NE, Mlodzik M, Rubin GM. Spacing differentiation in the developing Drosophila eye: a fibrinogen-related lateral inhibitor encoded by scabrous. Science (New York, N.Y.). 250: 1370-7. PMID 2175046 DOI: 10.1126/Science.2175046  1
1990 Mlodzik M, Baker NE, Rubin GM. Isolation and expression of scabrous, a gene regulating neurogenesis in Drosophila. Genes & Development. 4: 1848-61. PMID 2125959 DOI: 10.1101/Gad.4.11.1848  1
1990 Mlodzik M, Hiromi Y, Weber U, Goodman CS, Rubin GM. The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates. Cell. 60: 211-24. PMID 2105166 DOI: 10.1016/0092-8674(90)90737-Y  1
1990 Mlodzik M, Gibson G, Gehring WJ. Effects of ectopic expression of caudal during Drosophila development. Development (Cambridge, England). 109: 271-7. PMID 1976085  1
1988 Mlodzik M, Fjose A, Gehring WJ. Molecular structure and spatial expression of a homeobox gene from the labial region of the Antennapedia-complex. The Embo Journal. 7: 2569-78. PMID 2461299 DOI: 10.1002/J.1460-2075.1988.Tb03106.X  1
1987 Mlodzik M, Gehring WJ. Expression of the caudal gene in the germ line of Drosophila: formation of an RNA and protein gradient during early embryogenesis. Cell. 48: 465-78. PMID 2433048 DOI: 10.1016/0092-8674(87)90197-8  1
1987 Mlodzik M, Gehring WJ. Hierarchy of the genetic interactions that specify the anteroposterior segmentation pattern of the Drosophila embryo as monitored by caudal protein expression Development. 101: 421-435.  1
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