Robert Stanley Sherwin - Publications

Affiliations: 
Internal Medicine Yale University School of Medicine, New Haven, CT 
Area:
Diabetes

219 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Hwang JJ, Jiang L, Rangel ES, Fan X, Ding Y, Lam W, Leventhal J, Dai F, Rothman DL, Mason GF, Sherwin RS. Glycemic Variability and Brain Glucose Levels in T1DM. Diabetes. PMID 30327383 DOI: 10.2337/db18-0722  0.48
2015 Hwang JJ, Johnson A, Cline G, Belfort-DeAguiar R, Snegovskikh D, Khokhar B, Han CS, Sherwin RS. Fructose levels are markedly elevated in cerebrospinal fluid compared to plasma in pregnant women. Plos One. 10: e0128582. PMID 26035307 DOI: 10.1371/journal.pone.0128582  1
2014 Chan O, Sherwin RS. Is there cross talk between portal and hypothalamic glucose-sensing circuits? Diabetes. 63: 2617-9. PMID 25060894 DOI: 10.2337/db14-0755  1
2014 Belfort-Deaguiar R, Constable RT, Sherwin RS. Functional MRI signal fluctuations: a preclinical biomarker for cognitive impairment in type 2 diabetes? Diabetes. 63: 396-8. PMID 24464717 DOI: 10.2337/db13-1685  1
2014 Szepietowska B, Horvath TL, Sherwin RS. Role of synaptic plasticity and EphA5-ephrinA5 interaction within the ventromedial hypothalamus in response to recurrent hypoglycemia. Diabetes. 63: 1140-7. PMID 24222347 DOI: 10.2337/db13-1259  1
2013 Chan O, Sherwin R. Influence of VMH fuel sensing on hypoglycemic responses Trends in Endocrinology and Metabolism. 24: 616-624. PMID 24063974 DOI: 10.1016/j.tem.2013.08.005  1
2013 Li J, Qi D, Cheng H, Hu X, Miller EJ, Wu X, Russell KS, Mikush N, Zhang J, Xiao L, Sherwin RS, Young LH. Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart. Proceedings of the National Academy of Sciences of the United States of America. 110: 16133-8. PMID 24043794 DOI: 10.1073/pnas.1312775110  1
2013 Chan O, Paranjape SA, Horblitt A, Zhu W, Sherwin RS. Lactate-induced release of GABA in the ventromedial hypothalamus contributes to counterregulatory failure in recurrent hypoglycemia and diabetes. Diabetes. 62: 4239-46. PMID 23939392 DOI: 10.2337/db13-0770  1
2013 Szepietowska B, Zhu W, Sherwin RS. β2-Adrenergic receptor agonist administration promotes counter-regulatory responses and recovery from hypoglycaemia in rats. Diabetologia. 56: 2517-23. PMID 23933834 DOI: 10.1007/s00125-013-3009-7  1
2013 Gurr W, Shaw M, Herzog RI, Li Y, Sherwin R. Vaccination with single chain antigen receptors for islet-derived peptides presented on I-A(g7) delays diabetes in NOD mice by inducing anergy in self-reactiveT-cells. Plos One. 8: e69464. PMID 23894487 DOI: 10.1371/journal.pone.0069464  1
2013 Gulanski BI, De Feyter HM, Page KA, Belfort-DeAguiar R, Mason GF, Rothman DL, Sherwin RS. Increased brain transport and metabolism of acetate in hypoglycemia unawareness. The Journal of Clinical Endocrinology and Metabolism. 98: 3811-20. PMID 23796565 DOI: 10.1210/jc.2013-1701  0.32
2013 Beall C, Haythorne E, Fan X, Du Q, Jovanovic S, Sherwin RS, Ashford ML, McCrimmon RJ. Continuous hypothalamic K(ATP) activation blunts glucose counter-regulation in vivo in rats and suppresses K(ATP) conductance in vitro. Diabetologia. 56: 2088-92. PMID 23793715 DOI: 10.1007/s00125-013-2970-5  1
2013 Paranjape SA, Chan O, Zhu W, Acharya NK, Rogers AM, Hajnal A, Sherwin RS. Improvement in hepatic insulin sensitivity after Roux-en-Y gastric bypass in a rat model of obesity is partially mediated via hypothalamic insulin action. Diabetologia. 56: 2055-8. PMID 23783353 DOI: 10.1007/s00125-013-2952-7  1
2013 Page KA, Sinha R, Sherwin RS. Differential effects of fructose and glucose on cerebral blood flow--reply. Jama. 309: 1769. PMID 23632711 DOI: 10.1001/jama.2013.3367  1
2013 Reis SE, Patterson PD, Fitzgerald GA, Ford D, Sherwin RS, Solway J, Evanoff BA. The sharing partnership for innovative research in translation (SPIRiT) consortium: a model for collaboration across CTSA sites. Clinical and Translational Science. 6: 85-7. PMID 23601335 DOI: 10.1111/cts.12039  1
2013 Herzog RI, Jiang L, Herman P, Zhao C, Sanganahalli BG, Mason GF, Hyder F, Rothman DL, Sherwin RS, Behar KL. Lactate preserves neuronal metabolism and function following antecedent recurrent hypoglycemia. The Journal of Clinical Investigation. 123: 1988-98. PMID 23543056 DOI: 10.1172/JCI65105  1
2013 Singh R, De Aguiar RB, Naik S, Mani S, Ostadsharif K, Wencker D, Sotoudeh M, Malekzadeh R, Sherwin RS, Mani A. LRP6 enhances glucose metabolism by promoting TCF7L2-dependent insulin receptor expression and IGF receptor stabilization in humans. Cell Metabolism. 17: 197-209. PMID 23395167 DOI: 10.1016/j.cmet.2013.01.009  1
2013 Page KA, Chan O, Arora J, Belfort-Deaguiar R, Dzuira J, Roehmholdt B, Cline GW, Naik S, Sinha R, Constable RT, Sherwin RS. Effects of fructose vs glucose on regional cerebral blood flow in brain regions involved with appetite and reward pathways. Jama. 309: 63-70. PMID 23280226 DOI: 10.1001/jama.2012.116975  1
2013 Szepietowska B, Zhu W, Czyzyk J, Eid T, Sherwin RS. EphA5-EphrinA5 interactions within the ventromedial hypothalamus influence counterregulatory hormone release and local glutamine/glutamate balance during hypoglycemia. Diabetes. 62: 1282-8. PMID 23274893 DOI: 10.2337/db12-0982  1
2013 McNay EC, Teske JA, Kotz CM, Dunn-Meynell A, Levin BE, McCrimmon RJ, Sherwin RS. Long-term, intermittent, insulin-induced hypoglycemia produces marked obesity without hyperphagia or insulin resistance: a model for weight gain with intensive insulin therapy. American Journal of Physiology. Endocrinology and Metabolism. 304: E131-8. PMID 23169787 DOI: 10.1152/ajpendo.00262.2012  1
2013 Jastreboff AM, Sinha R, Lacadie C, Small DM, Sherwin RS, Potenza MN. Neural correlates of stress- and food cue-induced food craving in obesity: association with insulin levels. Diabetes Care. 36: 394-402. PMID 23069840 DOI: 10.2337/dc12-1112  1
2012 Sherwin R, Slayman C, Rockwell S, Herold K, Williams K, Carson R, Mane S, Seow H, Max J, Johnson T. Yale Center for Clinical Investigation: leveraging industry partnerships and research cores. Clinical and Translational Science. 5: 435-6. PMID 23253663 DOI: 10.1111/cts.12016  1
2012 Sherwin R, Jastreboff AM. Year in diabetes 2012: The diabetes tsunami Journal of Clinical Endocrinology and Metabolism. 97: 4293-4301. PMID 23185035 DOI: 10.1210/jc.2012-3487  1
2012 Lin SF, Fan X, Yeckel CW, Weinzimmer D, Mulnix T, Gallezot JD, Carson RE, Sherwin RS, Ding YS. Ex vivo and in vivo evaluation of the norepinephrine transporter ligand [11C]MRB for brown adipose tissue imaging. Nuclear Medicine and Biology. 39: 1081-6. PMID 22595487 DOI: 10.1016/j.nucmedbio.2012.04.005  1
2012 Chan O, Sherwin RS. Hypothalamic regulation of glucose-stimulated insulin secretion. Diabetes. 61: 564-5. PMID 22354931 DOI: 10.2337/db11-1846  1
2012 Yang L, Isoda F, Yen K, Kleopoulos SP, Janssen W, Fan X, Mastaitis J, Dunn-Meynell A, Levin B, McCrimmon R, Sherwin R, Musatov S, Mobbs CV. Hypothalamic Fkbp51 is induced by fasting, and elevated hypothalamic expression promotes obese phenotypes. American Journal of Physiology. Endocrinology and Metabolism. 302: E987-91. PMID 22318949 DOI: 10.1152/ajpendo.00474.2011  1
2012 Schafer RJ, Page KA, Arora J, Sherwin R, Constable RT. BOLD response to semantic and syntactic processing during hypoglycemia is load-dependent. Brain and Language. 120: 1-14. PMID 22000597 DOI: 10.1016/j.bandl.2011.07.003  1
2011 Herzog RI, Sherwin RS. Diabetes. Can tight glycemic control in diabetes benefit cognition? Nature Reviews. Neurology. 8: 124-6. PMID 22290574 DOI: 10.1038/nrneurol.2012.10  1
2011 Szepietowska B, Zhu W, Chan O, Horblitt A, Dziura J, Sherwin RS. Modulation of β-adrenergic receptors in the ventromedial hypothalamus influences counterregulatory responses to hypoglycemia. Diabetes. 60: 3154-8. PMID 22013013 DOI: 10.2337/db11-0432  1
2011 Page KA, Seo D, Belfort-DeAguiar R, Lacadie C, Dzuira J, Naik S, Amarnath S, Constable RT, Sherwin RS, Sinha R. Circulating glucose levels modulate neural control of desire for high-calorie foods in humans. The Journal of Clinical Investigation. 121: 4161-9. PMID 21926468 DOI: 10.1172/JCI57873  1
2011 Levin BE, Sherwin RS. Peripheral glucose homeostasis: does brain insulin matter? The Journal of Clinical Investigation. 121: 3392-5. PMID 21865650 DOI: 10.1172/JCI59653  1
2011 Paranjape SA, Chan O, Zhu W, Horblitt AM, Grillo CA, Wilson S, Reagan L, Sherwin RS. Chronic reduction of insulin receptors in the ventromedial hypothalamus produces glucose intolerance and islet dysfunction in the absence of weight gain. American Journal of Physiology. Endocrinology and Metabolism. 301: E978-83. PMID 21828334 DOI: 10.1152/ajpendo.00304.2011  1
2011 Herzog RI, Sherwin RS, Rothman DL. Insulin-induced hypoglycemia and its effect on the brain: unraveling metabolism by in vivo nuclear magnetic resonance. Diabetes. 60: 1856-8. PMID 21709281 DOI: 10.2337/db11-0498  1
2011 Tai N, Yasuda H, Xiang Y, Zhang L, Rodriguez-Pinto D, Yokono K, Sherwin R, Wong FS, Nagata M, Wen L. IL-10-conditioned dendritic cells prevent autoimmune diabetes in NOD and humanized HLA-DQ8/RIP-B7.1 mice Clinical Immunology. 139: 336-349. PMID 21458378 DOI: 10.1016/j.clim.2011.03.003  1
2011 Chan O, Paranjape S, Czyzyk D, Horblitt A, Zhu W, Ding Y, Fan X, Seashore M, Sherwin R. Increased GABAergic output in the ventromedial hypothalamus contributes to impaired hypoglycemic counterregulation in diabetic rats Diabetes. 60: 1582-1589. PMID 21411513 DOI: 10.2337/db10-1579  1
2011 Jastreboff AM, Potenza MN, Lacadie C, Hong KA, Sherwin RS, Sinha R. Body mass index, metabolic factors, and striatal activation during stressful and neutral-relaxing states: an FMRI study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 627-37. PMID 21048702 DOI: 10.1038/npp.2010.194  1
2011 Inzucchi SE, Sherwin RS. Type 2 Diabetes Mellitus Goldman's Cecil Medicine: Twenty Fourth Edition. 2: 1489-1499. DOI: 10.1016/B978-1-4377-1604-7.00237-2  1
2010 McCrimmon RJ, Sherwin RS. Hypoglycemia in type 1 diabetes. Diabetes. 59: 2333-9. PMID 20876723 DOI: 10.2337/db10-0103  1
2010 Huszarik K, Wright B, Keller C, Nikoopour E, Krougly O, Lee-Chan E, Qin HY, Cameron MJ, Gurr WK, Hill DJ, Sherwin RS, Kelvin DJ, Singh B. Adjuvant immunotherapy increases beta cell regenerative factor Reg2 in the pancreas of diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 185: 5120-9. PMID 20876350 DOI: 10.4049/jimmunol.1001596  1
2010 Sherwin RS, Weed MA. Volunteer caregivers and the management of a total blind/brittle type 1 diabetic student and researcher at yale. Diabetes Care. 33: e113. PMID 20668148 DOI: 10.2337/dc10-0880  1
2010 Zhu W, Czyzyk D, Paranjape SA, Zhou L, Horblitt A, Szabó G, Seashore MR, Sherwin RS, Chan O. Glucose prevents the fall in ventromedial hypothalamic GABA that is required for full activation of glucose counterregulatory responses during hypoglycemia. American Journal of Physiology. Endocrinology and Metabolism. 298: E971-7. PMID 20304763 DOI: 10.1152/ajpendo.00749.2009  1
2010 Paranjape SA, Chan O, Zhu W, Horblitt AM, McNay EC, Cresswell JA, Bogan JS, McCrimmon RJ, Sherwin RS. Influence of insulin in the ventromedial hypothalamus on pancreatic glucagon secretion in vivo. Diabetes. 59: 1521-7. PMID 20299468 DOI: 10.2337/db10-0014  1
2010 Osundiji MA, Zhou L, Shaw J, Moore SP, Yueh CY, Sherwin R, Heisler LK, Evans ML. Brain glucosamine boosts protective glucoprivic feeding. Endocrinology. 151: 1499-508. PMID 20179264 DOI: 10.1210/en.2009-0989  1
2010 McNay EC, Ong CT, McCrimmon RJ, Cresswell J, Bogan JS, Sherwin RS. Hippocampal memory processes are modulated by insulin and high-fat-induced insulin resistance. Neurobiology of Learning and Memory. 93: 546-53. PMID 20176121 DOI: 10.1016/j.nlm.2010.02.002  1
2010 Drucker DJ, Sherman SI, Gorelick FS, Bergenstal RM, Sherwin RS, Buse JB. Incretin-based therapies for the treatment of type 2 diabetes: evaluation of the risks and benefits. Diabetes Care. 33: 428-33. PMID 20103558 DOI: 10.2337/dc09-1499  1
2009 Hirshberg B, Qiu M, Cali AM, Sherwin R, Constable T, Calle RA, Tal MG. Pancreatic perfusion of healthy individuals and type 1 diabetic patients as assessed by magnetic resonance perfusion imaging. Diabetologia. 52: 1561-5. PMID 19488737 DOI: 10.1007/s00125-009-1406-8  1
2009 Fan X, Ding Y, Brown S, Zhou L, Shaw M, Vella MC, Cheng H, McNay EC, Sherwin RS, McCrimmon RJ. Hypothalamic AMP-activated protein kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of type 1 diabetes. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R1702-8. PMID 19357294 DOI: 10.1152/ajpregu.90600.2008  1
2009 Jiang L, Herzog RI, Mason GF, de Graaf RA, Rothman DL, Sherwin RS, Behar KL. Recurrent antecedent hypoglycemia alters neuronal oxidative metabolism in vivo. Diabetes. 58: 1266-74. PMID 19276443 DOI: 10.2337/db08-1664  1
2009 Page KA, Williamson A, Yu N, McNay EC, Dzuira J, McCrimmon RJ, Sherwin RS. Medium-chain fatty acids improve cognitive function in intensively treated type 1 diabetic patients and support in vitro synaptic transmission during acute hypoglycemia. Diabetes. 58: 1237-44. PMID 19223595 DOI: 10.2337/db08-1557  1
2009 Yeckel CW, Gulanski B, Zgorski ML, Dziura J, Parish R, Sherwin RS. Simple exercise recovery index for sympathetic overactivity is linked to insulin resistance. Medicine and Science in Sports and Exercise. 41: 505-15. PMID 19204601 DOI: 10.1249/MSS.0b013e31818afa2f  1
2009 Skyler JS, Bergenstal R, Bonow RO, Buse J, Deedwania P, Gale EA, Howard BV, Kirkman MS, Kosiborod M, Reaven P, Sherwin RS. Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA Diabetes Trials: a position statement of the American Diabetes Association and a Scientific Statement of the American College of Cardiology Foundation and the American Heart Association. Journal of the American College of Cardiology. 53: 298-304. PMID 19147051 DOI: 10.1016/j.jacc.2008.10.008  1
2009 Skyler JS, Bergenstal R, Bonow RO, Buse J, Deedwania P, Gale EA, Howard BV, Kirkman MS, Kosiborod M, Reaven P, Sherwin RS. Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA diabetes trials: a position statement of the American Diabetes Association and a scientific statement of the American College of Cardiology Foundation and the American Heart Association. Circulation. 119: 351-7. PMID 19095622 DOI: 10.1161/CIRCULATIONAHA.108.191305  1
2009 Skyler JS, Bergenstal R, Bonow RO, Buse J, Deedwania P, Gale EA, Howard BV, Kirkman MS, Kosiborod M, Reaven P, Sherwin RS. Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA diabetes trials: a position statement of the American Diabetes Association and a scientific statement of the American College of Cardiology Foundation and the American Heart Association. Diabetes Care. 32: 187-92. PMID 19092168 DOI: 10.2337/dc08-9026  1
2009 Page KA, Arora J, Qiu M, Relwani R, Constable RT, Sherwin RS. Small decrements in systemic glucose provoke increases in hypothalamic blood flow prior to the release of counterregulatory hormones. Diabetes. 58: 448-52. PMID 19017765 DOI: 10.2337/db08-1224  1
2009 Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, Zinman B. Medical management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy Diabetes Care. 32: 193-203. PMID 18945920 DOI: 10.2337/dc08-9025  1
2009 Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, Zinman B. Medical management of hyperglycaemia in type 2 diabetes mellitus: A consensus algorithm for the initiation and adjustment of therapy : Aonsensus statement from the American Diabetes Association and the European Association for the Study of Diabetes Diabetologia. 52: 17-30. PMID 18941734 DOI: 10.1007/s00125-008-1157-y  1
2009 Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, Zinman B. Medical management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy - A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes Clinical Diabetes. 27: 4-16. DOI: 10.2337/diaclin.27.1.4  1
2008 Fan X, Ding Y, Cheng H, Gram DX, Sherwin RS, McCrimmon RJ. Amplified hormonal counterregulatory responses to hypoglycemia in rats after systemic delivery of a SUR-1-selective K(+) channel opener? Diabetes. 57: 3327-34. PMID 18776135 DOI: 10.2337/db08-0793  1
2008 Sherwin RS. Bringing light to the dark side of insulin: a journey across the blood-brain barrier. Diabetes. 57: 2259-68. PMID 18753671 DOI: 10.2337/db08-9023  1
2008 Chan O, Cheng H, Herzog R, Czyzyk D, Zhu W, Wang A, McCrimmon RJ, Seashore MR, Sherwin RS. Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory responses after antecedent hypoglycemia. Diabetes. 57: 1363-70. PMID 18375441 DOI: 10.2337/db07-1559  1
2008 Herzog RI, Chan O, Yu S, Dziura J, McNay EC, Sherwin RS. Effect of acute and recurrent hypoglycemia on changes in brain glycogen concentration. Endocrinology. 149: 1499-504. PMID 18187548 DOI: 10.1210/en.2007-1252  1
2008 Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, Zinman B. Management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy: Update regarding thiazolidinediones: A consensus statement from the American Diabetes Association and the European Association for the study of diabetes Diabetes Care. 31: 173-175. PMID 18165348 DOI: 10.2337/dc08-9016  1
2008 Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, Zinman B. Management of hyperglycaemia in type 2 diabetes mellitus: A consensus algorithm for the initiation and adjustment of therapy - Update regarding the thiazolidinediones Diabetologia. 51: 8-11. PMID 18026926 DOI: 10.1007/s00125-007-0873-z  1
2008 McCrimmon RJ, Shaw M, Fan X, Cheng H, Ding Y, Vella MC, Zhou L, McNay EC, Sherwin RS. Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia. Diabetes. 57: 444-50. PMID 17977955 DOI: 10.2337/db07-0837  1
2008 Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, Zinman B. Management of hyperglycaemia in type 2 diabetes mellitus: A consensus algorithm for the initiation and adjustment of therapy: Update regarding the thiazolidinediones (Diabetologia DOI: 10.1007/s00125-007-0873-z) Diabetologia. 51: 522. DOI: 10.1007/s00125-007-0917-4  1
2007 Cheng H, Zhou L, Zhu W, Wang A, Tang C, Chan O, Sherwin RS, McCrimmon RJ. Type 1 corticotropin-releasing factor receptors in the ventromedial hypothalamus promote hypoglycemia-induced hormonal counterregulation. American Journal of Physiology. Endocrinology and Metabolism. 293: E705-12. PMID 17578887 DOI: 10.1152/ajpendo.00136.2007  1
2007 Tong Q, Ye C, McCrimmon RJ, Dhillon H, Choi B, Kramer MD, Yu J, Yang Z, Christiansen LM, Lee CE, Choi CS, Zigman JM, Shulman GI, Sherwin RS, Elmquist JK, et al. Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia. Cell Metabolism. 5: 383-93. PMID 17488640 DOI: 10.1016/j.cmet.2007.04.001  1
2007 Shaw MM, Gurr WK, McCrimmon RJ, Schorderet DF, Sherwin RS. 5'AMP-activated protein kinase alpha deficiency enhances stress-induced apoptosis in BHK and PC12 cells. Journal of Cellular and Molecular Medicine. 11: 286-98. PMID 17488477 DOI: 10.1111/j.1582-4934.2007.00023.x  1
2007 Kim S, Millet I, Kim HS, Kim JY, Han MS, Lee MK, Kim KW, Sherwin RS, Karin M, Lee MS. NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 1913-8. PMID 17267600 DOI: 10.1073/pnas.0610690104  1
2007 Kerr D, Cheyne E, Thomas P, Sherwin R. Influence of acute alcohol ingestion on the hormonal responses to modest hypoglycaemia in patients with Type 1 diabetes Diabetic Medicine. 24: 312-316. PMID 17263767 DOI: 10.1111/j.1464-5491.2006.02054.x  1
2007 Chan O, Lawson M, Zhu W, Beverly JL, Sherwin RS. ATP-sensitive K(+) channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia. Diabetes. 56: 1120-6. PMID 17251273 DOI: 10.2337/db06-1102  1
2007 Gurr W, Shaw M, Li Y, Sherwin R. RegII is a beta-cell protein and autoantigen in diabetes of NOD mice. Diabetes. 56: 34-40. PMID 17192462 DOI: 10.2337/db06-0669  1
2007 Driesen NR, Goldberg PA, Anderson AW, Tang L, Flanagan DE, Sherwin RS, Gore JC. Hypoglycemia reduces the blood-oxygenation level dependent signal in primary auditory and visual cortex: a functional magnetic resonance imaging study. Journal of Neuroscience Research. 85: 575-82. PMID 17154420 DOI: 10.1002/jnr.21146  1
2006 Nathan DM, Buse JB, Davidson MB, Heine RJ, Holman RR, Sherwin R, Zinman B. Management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy. A consensus statement from the American diabetes association and the European association for the study of diabetes Diabetes Care. 29: 1963-1972. PMID 16873813 DOI: 10.2337/dc06-9912  1
2006 Anderson AW, Heptulla RA, Driesen N, Flanagan D, Goldberg PA, Jones TW, Rife F, Sarofin H, Tamborlane W, Sherwin R, Gore JC. Effects of hypoglycemia on human brain activation measured with fMRI. Magnetic Resonance Imaging. 24: 693-7. PMID 16824963 DOI: 10.1016/j.mri.2006.03.013  1
2006 Nathan DM, Buse JB, Davidson MB, Heine RJ, Holman RR, Sherwin R, Zinman B. Management of hyperglycaemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy - A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes Diabetologia. 49: 1711-1721. PMID 16802130 DOI: 10.1007/s00125-006-0316-2  1
2006 McCrimmon RJ, Song Z, Cheng H, McNay EC, Weikart-Yeckel C, Fan X, Routh VH, Sherwin RS. Corticotrophin-releasing factor receptors within the ventromedial hypothalamus regulate hypoglycemia-induced hormonal counterregulation. The Journal of Clinical Investigation. 116: 1723-30. PMID 16741581 DOI: 10.1172/JCI27775  1
2006 McCrimmon RJ, Fan X, Cheng H, McNay E, Chan O, Shaw M, Ding Y, Zhu W, Sherwin RS. Activation of AMP-activated protein kinase within the ventromedial hypothalamus amplifies counterregulatory hormone responses in rats with defective counterregulation. Diabetes. 55: 1755-60. PMID 16731839 DOI: 10.2337/db05-1359  1
2006 Du W, Wong FS, Li MO, Peng J, Qi H, Flavell RA, Sherwin R, Wen L. TGF-β signaling is required for the function of insulin-reactive T regulatory cells Journal of Clinical Investigation. 116: 1360-1370. PMID 16670772 DOI: 10.1172/JCI27030  1
2006 Goldberg PA, Weiss R, McCrimmon RJ, Hintz EV, Dziura JD, Sherwin RS. Antecedent hypercortisolemia is not primarily responsible for generating hypoglycemia-associated autonomic failure. Diabetes. 55: 1121-6. PMID 16567537 DOI: 10.2337/diabetes.55.04.06.db05-1169  1
2006 McNay EC, Williamson A, McCrimmon RJ, Sherwin RS. Cognitive and neural hippocampal effects of long-term moderate recurrent hypoglycemia. Diabetes. 55: 1088-95. PMID 16567533 DOI: 10.2337/diabetes.55.04.06.db05-1314  1
2006 Chan O, Zhu W, Ding Y, McCrimmon RJ, Sherwin RS. Blockade of GABA(A) receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia. Diabetes. 55: 1080-7. PMID 16567532 DOI: 10.2337/diabetes.55.04.06.db05-0958  1
2006 Diano S, Farr SA, Benoit SC, McNay EC, da Silva I, Horvath B, Gaskin FS, Nonaka N, Jaeger LB, Banks WA, Morley JE, Pinto S, Sherwin RS, Xu L, Yamada KA, et al. Ghrelin controls hippocampal spine synapse density and memory performance. Nature Neuroscience. 9: 381-8. PMID 16491079 DOI: 10.1038/nn1656  1
2006 McNay EC, Canal CE, Sherwin RS, Gold PE. Modulation of memory with septal injections of morphine and glucose: effects on extracellular glucose levels in the hippocampus. Physiology & Behavior. 87: 298-303. PMID 16343563 DOI: 10.1016/j.physbeh.2005.10.016  1
2006 Millet I, Wong FS, Gurr W, Wen L, Zawalich W, Green EA, Flavell RA, Sherwin RS. Targeted expression of the anti-apoptotic gene CrmA to NOD pancreatic islets protects from autoimmune diabetes. Journal of Autoimmunity. 26: 7-15. PMID 16338119 DOI: 10.1016/j.jaut.2005.10.005  1
2005 McCrimmon RJ, Evans ML, Fan X, McNay EC, Chan O, Ding Y, Zhu W, Gram DX, Sherwin RS. Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats. Diabetes. 54: 3169-74. PMID 16249441 DOI: 10.2337/diabetes.54.11.3169  1
2005 Inzucchi SE, Sherwin RS. The prevention of type 2 diabetes mellitus. Endocrinology and Metabolism Clinics of North America. 34: 199-219, viii. PMID 15752928 DOI: 10.1016/j.ecl.2004.11.008  1
2005 Cavus I, Kasoff WS, Cassaday MP, Jacob R, Gueorguieva R, Sherwin RS, Krystal JH, Spencer DD, Abi-Saab WM. Extracellular metabolites in the cortex and hippocampus of epileptic patients. Annals of Neurology. 57: 226-35. PMID 15668975 DOI: 10.1002/ana.20380  1
2005 Yeckel CW, Taksali SE, Dziura J, Weiss R, Burgert TS, Sherwin RS, Tamborlane WV, Caprio S. The normal glucose tolerance continuum in obese youth: evidence for impairment in beta-cell function independent of insulin resistance. The Journal of Clinical Endocrinology and Metabolism. 90: 747-54. PMID 15522932 DOI: 10.1210/jc.2004-1258  1
2004 Evans ML, McCrimmon RJ, Flanagan DE, Keshavarz T, Fan X, McNay EC, Jacob RJ, Sherwin RS. Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses. Diabetes. 53: 2542-51. PMID 15448082 DOI: 10.2337/diabetes.53.10.2542  1
2004 Qvisth V, Hagström-Toft E, Enoksson S, Sherwin RS, Sjöberg S, Bolinder J. Combined hyperinsulinemia and hyperglycemia, but not hyperinsulinemia alone, suppress human skeletal muscle lipolytic activity in vivo. The Journal of Clinical Endocrinology and Metabolism. 89: 4693-700. PMID 15356082 DOI: 10.1210/jc.2003-030656  1
2004 McCrimmon RJ, Fan X, Ding Y, Zhu W, Jacob RJ, Sherwin RS. Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus. Diabetes. 53: 1953-8. PMID 15277372 DOI: 10.2337/diabetes.53.8.1953  1
2004 Goldberg PA, Siegel MD, Russell RR, Sherwin RS, Halickman JI, Cooper DA, Dziura JD, Inzucchi SE. Experience with the continuous glucose monitoring system in a medical intensive care unit. Diabetes Technology & Therapeutics. 6: 339-47. PMID 15198837 DOI: 10.1089/152091504774198034  1
2004 Weiss R, Dziura J, Burgert TS, Tamborlane WV, Taksali SE, Yeckel CW, Allen K, Lopes M, Savoye M, Morrison J, Sherwin RS, Caprio S. Obesity and the metabolic syndrome in children and adolescents. The New England Journal of Medicine. 350: 2362-74. PMID 15175438 DOI: 10.1056/NEJMoa031049  1
2004 Cheyne EH, Sherwin RS, Lunt MJ, Cavan DA, Thomas PW, Kerr D. Influence of alcohol on cognitive performance during mild hypoglycaemia; implications for Type 1 diabetes. Diabetic Medicine : a Journal of the British Diabetic Association. 21: 230-7. PMID 15008832 DOI: 10.1111/j.1464-5491.2004.01154.x  1
2004 Stiles B, Wang Y, Stahl A, Bassilian S, Lee WP, Kim YJ, Sherwin R, Devaskar S, Lesche R, Magnuson MA, Wu H. Live-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity Proceedings of the National Academy of Sciences of the United States of America. 101: 2082-2087. PMID 14769918 DOI: 10.1073/pnas.0308617100  1
2004 McNay EC, Sherwin RS. Effect of recurrent hypoglycemia on spatial cognition and cognitive metabolism in normal and diabetic rats. Diabetes. 53: 418-25. PMID 14747293 DOI: 10.2337/diabetes.53.2.418  1
2004 Goldberg PA, Siegel MD, Sherwin RS, Halickman JI, Lee M, Bailey VA, Lee SL, Dziura JD, Inzucchi SE. Implementation of a safe and effective insulin infusion protocol in a medical intensive care unit. Diabetes Care. 27: 461-7. PMID 14747229 DOI: 10.2337/diacare.27.2.461  1
2004 McNay EC, Sherwin RS. From artificial cerebro-spinal fluid (aCSF) to artificial extracellular fluid (aECF): microdialysis perfusate composition effects on in vivo brain ECF glucose measurements. Journal of Neuroscience Methods. 132: 35-43. PMID 14687673 DOI: 10.1016/j.jneumeth.2003.08.014  1
2003 McCrimmon RJ, Jacob RJ, Fan X, McNay EC, Sherwin RS. Effects of recurrent antecedent hypoglycaemia and chronic hyperglycaemia on brainstem extra-cellular glucose concentrations during acute hypoglycaemia in conscious diabetic BB rats. Diabetologia. 46: 1658-61. PMID 14600813 DOI: 10.1007/s00125-003-1231-4  1
2003 Heptulla RA, Stewart A, Enocksson S, Rife F, Ma TY, Sherwin RS, Tamborlane WV, Caprio S. In situ evidence that peripheral insulin resistance in adolescents with poorly controlled type 1 diabetes is associated with impaired suppression of lipolysis: a microdialysis study. Pediatric Research. 53: 830-5. PMID 12702748 DOI: 10.1203/01.PDR.0000059552.08913.B7  1
2003 Enoksson S, Caprio SK, Rife F, Shulman GI, Tamborlane WV, Sherwin RS. Defective activation of skeletal muscle and adipose tissue lipolysis in type 1 diabetes mellitus during hypoglycemia. The Journal of Clinical Endocrinology and Metabolism. 88: 1503-11. PMID 12679430 DOI: 10.1210/jc.2002-021013  1
2003 Watson JM, Sherwin RS, Deary IJ, Scott L, Kerr D. Dissociation of augmented physiological, hormonal and cognitive responses to hypoglycaemia with sustained caffeine use. Clinical Science (London, England : 1979). 104: 447-54. PMID 12653691 DOI: 10.1042/  1
2003 Borg MA, Tamborlane WV, Shulman GI, Sherwin RS. Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation. Diabetes. 52: 663-6. PMID 12606506 DOI: 10.2337/diabetes.52.3.663  1
2003 Flanagan DE, Keshavarz T, Evans ML, Flanagan S, Fan X, Jacob RJ, Sherwin RS. Role of corticotrophin-releasing hormone in the impairment of counterregulatory responses to hypoglycemia. Diabetes. 52: 605-13. PMID 12606499 DOI: 10.2337/diabetes.52.3.605  1
2003 Flanagan DE, Evans ML, Monsod TP, Rife F, Heptulla RA, Tamborlane WV, Sherwin RS. The influence of insulin on circulating ghrelin. American Journal of Physiology. Endocrinology and Metabolism. 284: E313-6. PMID 12531744 DOI: 10.1152/ajpendo.00569.2001  1
2003 Sherwin RS, Anderson RM, Buse JB, Chin MH, Eddy D, Fradkin J, Ganiats TG, Ginsberg H, Kahn R, Nwankwo R, Rewers M, Schlessinger L, Stern M, Vinicor F, Zinman B, et al. The prevention or delay of type 2 diabetes. Diabetes Care. 26: S62-9. PMID 12502620  1
2002 Evans ML, Sherwin RS. Blood glucose and the brain in diabetes: between a rock and a hard place? Current Diabetes Reports. 2: 101-2. PMID 12643129  1
2002 Evans ML, Sherwin RS. Brain glucose metabolism and hypoglycaemia. Diabetes, Nutrition & Metabolism. 15: 294-6; discussion 29. PMID 12625472  1
2002 Jacob RJ, Fan X, Evans ML, Dziura J, Sherwin RS. Brain glucose levels are elevated in chronically hyperglycemic diabetic rats: no evidence for protective adaptation by the blood brain barrier. Metabolism: Clinical and Experimental. 51: 1522-4. PMID 12489061 DOI: 10.1053/meta.2002.36347  1
2002 McCrimmon RJ, Evans ML, Jacob RJ, Fan X, Zhu Y, Shulman GI, Sherwin RS. AICAR and phlorizin reverse the hypoglycemia-specific defect in glucagon secretion in the diabetic BB rat. American Journal of Physiology. Endocrinology and Metabolism. 283: E1076-83. PMID 12376337 DOI: 10.1152/ajpendo.00195.2002  1
2002 Jun HS, Chung YH, Han J, Kim A, Yoo SS, Sherwin RS, Yoon JW. Prevention of autoimmune diabetes by immunogene therapy using recombinant vaccinia virus expressing glutamic acid decarboxylase. Diabetologia. 45: 668-76. PMID 12107747 DOI: 10.1007/s00125-002-0806-9  1
2002 Monsod TP, Flanagan DE, Rife F, Saenz R, Caprio S, Sherwin RS, Tamborlane WV. Do sensor glucose levels accurately predict plasma glucose concentrations during hypoglycemia and hyperinsulinemia? Diabetes Care. 25: 889-93. PMID 11978686 DOI: 10.2337/diacare.25.5.889  1
2002 Sherwin RS, Anderson RM, Buse JB, Chin MH, Eddy D, Fradkin J, Ganiats TG, Ginsberg HN, Kahn R, Nwankwo R, Rewers M, Schlessinger L, Stem M, Vinicor F, Zinman B. The prevention or delay of type 2 diabetes: American Diabetes Association and National Institute of Diabetes, Digestive and Kidney Diseases Diabetes Care. 25: 742-749. PMID 11919135 DOI: 10.2337/diacare.25.4.742  1
2002 Sinha R, Fisch G, Teague B, Tamborlane WV, Banyas B, Allen K, Savoye M, Rieger V, Taksali S, Barbetta G, Sherwin RS, Caprio S. Prevalence of impaired glucose tolerance among children and adolescents with marked obesity. The New England Journal of Medicine. 346: 802-10. PMID 11893791 DOI: 10.1056/NEJMoa012578  1
2002 Abi-Saab WM, Maggs DG, Jones T, Jacob R, Srihari V, Thompson J, Kerr D, Leone P, Krystal JH, Spencer DD, During MJ, Sherwin RS. Striking differences in glucose and lactate levels between brain extracellular fluid and plasma in conscious human subjects: effects of hyperglycemia and hypoglycemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 271-9. PMID 11891432 DOI: 10.1097/00004647-200203000-00004  1
2002 Gurr W, Yavari R, Wen L, Shaw M, Mora C, Christa L, Sherwin RS. A Reg family protein is overexpressed in islets from a patient with new-onset type 1 diabetes and acts as T-cell autoantigen in NOD mice. Diabetes. 51: 339-46. PMID 11812740  1
2001 Turner BC, Jenkins E, Kerr D, Sherwin RS, Cavan DA. The effect of evening alcohol consumption on next-morning glucose control in type 1 diabetes. Diabetes Care. 24: 1888-93. PMID 11679452  1
2001 Russell RR, Chyun D, Song S, Sherwin RS, Tamborlane WV, Lee FA, Pfeifer MA, Rife F, Wackers FJ, Young LH. Cardiac responses to insulin-induced hypoglycemia in nondiabetic and intensively treated type 1 diabetic patients. American Journal of Physiology. Endocrinology and Metabolism. 281: E1029-36. PMID 11595660  1
2001 Heptulla RA, Tamborlane WV, Ma TY, Rife F, Sherwin RS. Oral glucose augments the counterregulatory hormone response during insulin-induced hypoglycemia in humans. The Journal of Clinical Endocrinology and Metabolism. 86: 645-8. PMID 11158023 DOI: 10.1210/jcem.86.2.7198  1
2001 Alavi A, Chamberlain J, Cherrington AD, Convit A, Craft S, Cryer PE, Davis SN, Davison S, De Leon M, DeRosa M, Drucker D, Albert M, Evans M, Feldman E, Fischbach GD, ... ... Sherwin RS, et al. Workshop on hypoglycemia and the brain Diabetes Technology and Therapeutics. 3: 469-516. DOI: 10.1089/15209150152607259  1
2000 Enoksson S, Talbot M, Rife F, Tamborlane WV, Sherwin RS, Caprio S. Impaired in vivo stimulation of lipolysis in adipose tissue by selective beta2-adrenergic agonist in obese adolescent girls. Diabetes. 49: 2149-53. PMID 11118019  1
2000 Yoon JW, Sherwin RS, Kwon H, Jun HS. Has GAD a central role in type 1 diabetes? Journal of Autoimmunity. 15: 273-8. PMID 11040067 DOI: 10.1006/jaut.2000.0442  1
2000 Kennan RP, Jacob RJ, Sherwin RS, Gore JC. Effects of hypoglycemia on functional magnetic resonance imaging response to median nerve stimulation in the rat brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 1352-9. PMID 10994857 DOI: 10.1097/00004647-200009000-00010  1
2000 Heptulla RA, Tamborlane WV, Cavaghan M, Bronson M, Limb C, Ma YZ, Sherwin RS, Caprio S. Augmentation of alimentary insulin secretion despite similar gastric inhibitory peptide (GIP) responses in juvenile obesity. Pediatric Research. 47: 628-33. PMID 10813588  1
2000 Millet I, Phillips RJ, Sherwin RS, Ghosh S, Voll RE, Flavell RA, Vignery A, Rincón M. Inhibition of NF-kappaB activity and enhancement of apoptosis by the neuropeptide calcitonin gene-related peptide. The Journal of Biological Chemistry. 275: 15114-21. PMID 10809748  1
2000 Borg WP, Sherwin RS. Classification of diabetes mellitus. Advances in Internal Medicine. 45: 279-95. PMID 10635052  1
1999 McCrimmon RJ, Sherwin RS. Effect of pancreatic transplantation on counterregulatory hormonal responses to hypoglycaemia. Acta Diabetologica. 36: 11-20. PMID 10436247  1
1999 Attia N, Caprio S, Jones TW, Heptulla R, Holcombe J, Silver D, Sherwin RS, Tamborlane WV. Changes in free insulin-like growth factor-1 and leptin concentrations during acute metabolic decompensation in insulin withdrawn patients with type 1 diabetes. The Journal of Clinical Endocrinology and Metabolism. 84: 2324-8. PMID 10404797 DOI: 10.1210/jcem.84.7.5861  1
1999 Yoon JW, Yoon CS, Lim HW, Huang QQ, Kang Y, Pyun KH, Hirasawa K, Sherwin RS, Jun HS. Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells. Science (New York, N.Y.). 284: 1183-7. PMID 10325232 DOI: 10.1126/science.284.5417.1183  1
1999 Borg MA, Borg WP, Tamborlane WV, Brines ML, Shulman GI, Sherwin RS. Chronic hypoglycemia and diabetes impair counterregulation induced by localized 2-deoxy-glucose perfusion of the ventromedial hypothalamus in rats. Diabetes. 48: 584-7. PMID 10078560  1
1999 Jacob RJ, Dziura J, Blumberg M, Morgen JP, Sherwin RS. Effects of recurrent hypoglycemia on brainstem function in diabetic BB rats: protective adaptation during acute hypoglycemia. Diabetes. 48: 141-5. PMID 9892235 DOI: 10.2337/diabetes.48.1.141  1
1999 Young LH, Renfu Y, Hu X, Chong S, Hasan S, Jacob R, Sherwin RS. Insulin-like growth factor I stimulates cardiac myosin heavy chain and actin synthesis in the awake rat. The American Journal of Physiology. 276: E143-50. PMID 9886960  1
1998 Diamond MP, Grainger D, Diamond MC, Sherwin RS, Defronzo RA. Effects of methyltestosterone on insulin secretion and sensitivity in women. The Journal of Clinical Endocrinology and Metabolism. 83: 4420-5. PMID 9851788 DOI: 10.1210/jcem.83.12.5333  1
1998 During MJ, Xu R, Young D, Kaplitt MG, Sherwin RS, Leone P. Peroral gene therapy of lactose intolerance using an adeno-associated virus vector. Nature Medicine. 4: 1131-5. PMID 9771745 DOI: 10.1038/2625  1
1998 Wen L, Wong FS, Burkly L, Altieri M, Mamalaki C, Kioussis D, Flavell RA, Sherwin RS. Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice. The Journal of Clinical Investigation. 102: 947-57. PMID 9727063 DOI: 10.1172/JCI2723  1
1998 Geng L, Solimena M, Flavell RA, Sherwin RS, Hayday AC. Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate disease. Proceedings of the National Academy of Sciences of the United States of America. 95: 10055-60. PMID 9707599 DOI: 10.1073/pnas.95.17.10055  1
1998 Jones TW, Porter P, Sherwin RS, Davis EA, O'Leary P, Frazer F, Byrne G, Stick S, Tamborlane WV. Decreased epinephrine responses to hypoglycemia during sleep. The New England Journal of Medicine. 338: 1657-62. PMID 9614256 DOI: 10.1056/NEJM199806043382303  1
1998 Attia N, Tamborlane WV, Heptulla R, Maggs D, Grozman A, Sherwin RS, Caprio S. The metabolic syndrome and insulin-like growth factor I regulation in adolescent obesity. The Journal of Clinical Endocrinology and Metabolism. 83: 1467-71. PMID 9589640 DOI: 10.1210/jcem.83.5.4827  1
1998 Robinson C, Tamborlane WV, Maggs DG, Enoksson S, Sherwin RS, Silver D, Shulman GI, Caprio S. Effect of insulin on glycerol production in obese adolescents. The American Journal of Physiology. 274: E737-43. PMID 9575836  1
1998 Zekzer D, Wong FS, Ayalon O, Millet I, Altieri M, Shintani S, Solimena M, Sherwin RS. GAD-reactive CD4+ Th1 cells induce diabetes in NOD/SCID mice. The Journal of Clinical Investigation. 101: 68-73. PMID 9421467 DOI: 10.1172/JCI119878  1
1998 Maggs DG, Sherwin RS. Mechanisms of the sympathoadrenal response to hypoglycemia. Advances in Pharmacology (San Diego, Calif.). 42: 622-6. PMID 9327979 DOI: 10.1016/S1054-3589(08)60828-5  1
1997 Petersen KF, Jacob R, West AB, Sherwin RS, Shulman GI. Effects of insulin-like growth factor I on glucose metabolism in rats with liver cirrhosis. The American Journal of Physiology. 273: E1189-93. PMID 9435535  1
1997 Heptulla RA, Boulware SD, Caprio S, Silver D, Sherwin RS, Tamborlane WV. Decreased insulin sensitivity and compensatory hyperinsulinemia after hormone treatment in children with short stature. The Journal of Clinical Endocrinology and Metabolism. 82: 3234-8. PMID 9329345 DOI: 10.1210/jcem.82.10.4302  1
1997 Maggs DG, Borg WP, Sherwin RS. Microdialysis techniques in the study of brain and skeletal muscle. Diabetologia. 40: S75-82. PMID 9248705 DOI: 10.1007/s001250051410  1
1997 Zekzer D, Wong FS, Wen L, Altieri M, Gurlo T, von Grafenstein H, Sherwin RS. Inhibition of diabetes by an insulin-reactive CD4 T-cell clone in the nonobese diabetic mouse. Diabetes. 46: 1124-32. PMID 9200646  1
1997 Jones TW, Borg WP, Borg MA, Boulware SD, McCarthy G, Silver D, Tamborlane WV, Sherwin RS. Resistance to neuroglycopenia: an adaptive response during intensive insulin treatment of diabetes. The Journal of Clinical Endocrinology and Metabolism. 82: 1713-8. PMID 9177369 DOI: 10.1210/jcem.82.6.3993  1
1997 Thomas M, Sherwin RS, Murphy J, Kerr D. Importance of cerebral blood flow to the recognition of and physiological responses to hypoglycemia. Diabetes. 46: 829-33. PMID 9133551  1
1997 Limb C, Tamborlane WV, Sherwin RS, Pederson R, Caprio S. Acute incretin response to oral glucose is associated with stimulation of gastric inhibitory polypeptide, not glucagon-like peptide in young subjects. Pediatric Research. 41: 364-7. PMID 9078536 DOI: 10.1203/00006450-199703000-00010  1
1997 Borg MA, Sherwin RS, Borg WP, Tamborlane WV, Shulman GI. Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats. The Journal of Clinical Investigation. 99: 361-5. PMID 9006005 DOI: 10.1172/JCI119165  1
1997 Jacob RJ, Dziura J, Medwick MB, Leone P, Caprio S, During M, Shulman GI, Sherwin RS. The effect of leptin is enhanced by microinjection into the ventromedial hypothalamus. Diabetes. 46: 150-2. PMID 8971096  1
1997 Maggs DG, Jacob R, Rife F, Caprio S, Tamborlane WV, Sherwin RS. Counterregulation in peripheral tissues: effect of systemic hypoglycemia on levels of substrates and catecholamines in human skeletal muscle and adipose tissue. Diabetes. 46: 70-6. PMID 8971084  1
1996 Caprio S, Bronson M, Sherwin RS, Rife F, Tamborlane WV. Co-existence of severe insulin resistance and hyperinsulinaemia in pre-adolescent obese children. Diabetologia. 39: 1489-97. PMID 8960831 DOI: 10.1007/s001250050603  1
1996 Jacob RJ, Dziura J, Morgen JP, Shulman GI, Sherwin RS. Time course of the defective alpha-cell response to hypoglycemia in diabetic BB rats. Metabolism: Clinical and Experimental. 45: 1422-6. PMID 8931649 DOI: 10.1016/S0026-0495(96)90125-0  1
1996 McInerney MF, Flynn JC, Goldblatt PJ, Najjar SM, Sherwin RS, Janeway CA. High density insulin receptor-positive T lymphocytes from nonobese diabetic mice transfer insulitis and diabetes. Journal of Immunology (Baltimore, Md. : 1950). 157: 3716-26. PMID 8871675  1
1996 Caprio S, Tamborlane WV, Silver D, Robinson C, Leibel R, McCarthy S, Grozman A, Belous A, Maggs D, Sherwin RS. Hyperleptinemia: an early sign of juvenile obesity. Relations to body fat depots and insulin concentrations. The American Journal of Physiology. 271: E626-30. PMID 8843759  1
1996 Jacob R, Hu X, Niederstock D, Hasan S, McNulty PH, Sherwin RS, Young LH. IGF-I stimulation of muscle protein synthesis in the awake rat: permissive role of insulin and amino acids. The American Journal of Physiology. 270: E60-6. PMID 8772474  1
1996 Debrah K, Sherwin RS, Murphy J, Kerr D. Effect of caffeine on recognition of and physiological responses to hypoglycaemia in insulin-dependent diabetes. Lancet. 347: 19-24. PMID 8531542 DOI: 10.1016/S0140-6736(96)91557-3  1
1995 Diamond MP, Thornton K, Connolly-Diamond M, Sherwin RS, DeFronzo RA. Reciprocal variations in insulin-stimulated glucose uptake and pancreatic insulin secretion in women with normal glucose tolerance. Journal of the Society For Gynecologic Investigation. 2: 708-15. PMID 9420879  1
1995 Thornton KL, DeFronzo RA, Sherwin RS, Diamond MP. Micronized estradiol and progesterone: effects on carbohydrate metabolism in reproductive-age women. Journal of the Society For Gynecologic Investigation. 2: 643-52. PMID 9420871  1
1995 Borg WP, Sherwin RS, During MJ, Borg MA, Shulman GI. Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release. Diabetes. 44: 180-4. PMID 7859938  1
1995 Jones TW, Borg WP, Boulware SD, McCarthy G, Sherwin RS, Tamborlane WV. Enhanced adrenomedullary response and increased susceptibility to neuroglycopenia: mechanisms underlying the adverse effects of sugar ingestion in healthy children. The Journal of Pediatrics. 126: 171-7. PMID 7844661 DOI: 10.1016/S0022-3476(95)70541-4  1
1995 Fryburg DA, Gelfand RA, Jahn LA, Oliveras D, Sherwin RS, Sacca L, Barrett EJ. Effects of epinephrine on human muscle glucose and protein metabolism. The American Journal of Physiology. 268: E55-9. PMID 7840182  1
1995 Dirkx R, Thomas A, Li L, Lernmark A, Sherwin RS, De Camilli P, Solimena M. Targeting of the 67-kDa isoform of glutamic acid decarboxylase to intracellular organelles is mediated by its interaction with the NH2-terminal region of the 65-kDa isoform of glutamic acid decarboxylase. The Journal of Biological Chemistry. 270: 2241-6. PMID 7836456  1
1995 During MJ, Leone P, Davis KE, Kerr D, Sherwin RS. Glucose modulates rat substantia nigra GABA release in vivo via ATP-sensitive potassium channels. The Journal of Clinical Investigation. 95: 2403-8. PMID 7738204 DOI: 10.1172/JCI117935  1
1995 Caprio S, Hyman LD, Limb C, McCarthy S, Lange R, Sherwin RS, Shulman G, Tamborlane WV. Central adiposity and its metabolic correlates in obese adolescent girls. The American Journal of Physiology. 269: E118-26. PMID 7631766  1
1995 Jacob RJ, Weber AB, Dziura J, Morgen J, Sherwin RS. Brainstem dysfunction is provoked by a less pronounced hypoglycemic stimulus in diabetic BB rats. Diabetes. 44: 900-5. PMID 7621994  1
1995 Maggs DG, Jacob R, Rife F, Lange R, Leone P, During MJ, Tamborlane WV, Sherwin RS. Interstitial fluid concentrations of glycerol, glucose, and amino acids in human quadricep muscle and adipose tissue. Evidence for significant lipolysis in skeletal muscle. The Journal of Clinical Investigation. 96: 370-7. PMID 7615807 DOI: 10.1172/JCI118043  1
1995 Boulware SD, Tamborlane WV, Sherwin RS. Effects of IGF-I on carbohydrate and lipid metabolism Diabetes Reviews. 3: 196-205.  1
1994 Borg WP, During MJ, Sherwin RS, Borg MA, Brines ML, Shulman GI. Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia. The Journal of Clinical Investigation. 93: 1677-82. PMID 8163668 DOI: 10.1172/JCI117150  1
1994 Boulware SD, Tamborlane WV, Rennert NJ, Gesundheit N, Sherwin RS. Comparison of the metabolic effects of recombinant human insulin-like growth factor-I and insulin. Dose-response relationships in healthy young and middle-aged adults. The Journal of Clinical Investigation. 93: 1131-9. PMID 8132753 DOI: 10.1172/JCI117065  1
1994 Sherwin RS, Borg WP, Boulware SD. Metabolic effects of insulin-like growth factor I in normal humans. Hormone Research. 41: 97-101; discussion 1. PMID 8088711 DOI: 10.1159/000183968  1
1994 Louard RJ, Bhushan R, Gelfand RA, Barrett EJ, Sherwin RS. Glucocorticoids antagonize insulin's antiproteolytic action on skeletal muscle in humans. The Journal of Clinical Endocrinology and Metabolism. 79: 278-84. PMID 8027242 DOI: 10.1210/jcem.79.1.8027242  1
1994 Caprio S, Cline G, Boulware S, Permanente C, Shulman GI, Sherwin RS, Tamborlane WV. Effects of puberty and diabetes on metabolism of insulin-sensitive fuels. The American Journal of Physiology. 266: E885-91. PMID 8023918  1
1994 Weber AB, Jacob RJ, Stuart P, Davis J, Sherwin RS. Moderate hypoglycemia impairs the function of the inferior colliculus in the awake rat. Metabolism: Clinical and Experimental. 43: 1329-31. PMID 7968585 DOI: 10.1016/0026-0495(94)90023-X  1
1993 Jones TW, Boulware SD, Caprio S, Merkel P, Amiel SA, Pearson HA, Sherwin RS, Tamborlane WV. Correction of hyperinsulinemia by glyburide treatment in nondiabetic patients with thalassemia major. Pediatric Research. 33: 497-500. PMID 8511023 DOI: 10.1203/00006450-199305000-00015  1
1993 Caprio S, Tamborlane WV, Zych K, Gerow K, Sherwin RS. Loss of potentiating effect of hypoglycemia on the glucagon response to hyperaminoacidemia in IDDM. Diabetes. 42: 550-5. PMID 8454105  1
1993 Rennert NJ, Caprio S, Sherwin RS. Insulin-like growth factor I inhibits glucose-stimulated insulin secretion but does not impair glucose metabolism in normal humans. The Journal of Clinical Endocrinology and Metabolism. 76: 804-6. PMID 8445040 DOI: 10.1210/jcem.76.3.8445040  1
1993 Kerr D, Tamborlane WV, Rife F, Sherwin RS. Effect of insulin-like growth factor-1 on the responses to and recognition of hypoglycemia in humans. A comparison with insulin. The Journal of Clinical Investigation. 91: 141-7. PMID 8423214 DOI: 10.1172/JCI116163  1
1993 Kerr D, Diamond MP, Tamborlane WV, Kerr S, Sherwin RS. Influence of counterregulatory hormones, independently of hypoglycaemia, on cognitive function, warning symptoms and glucose kinetics. Clinical Science (London, England : 1979). 85: 197-202. PMID 8403788  1
1993 Kerr D, Sherwin RS, Pavalkis F, Fayad PB, Sikorski L, Rife F, Tamborlane WV, During MJ. Effect of caffeine on the recognition of and responses to hypoglycemia in humans. Annals of Internal Medicine. 119: 799-804. PMID 8379601  1
1993 Rossi G, Lapaczewski P, Diamond MP, Jacob RJ, Shulman GI, Sherwin RS. Inhibitory effect of pregnancy on counterregulatory hormone responses to hypoglycemia in awake rat. Diabetes. 42: 1440-5. PMID 8375583  1
1993 Rossi G, Sherwin RS, Penzias AS, Lapaczewski P, Jacob RJ, Shulman GI, Diamond MP. Temporal changes in insulin resistance and secretion in 24-h-fasted conscious pregnant rats. The American Journal of Physiology. 265: E845-51. PMID 8279539  1
1993 Powell AM, Sherwin RS, Shulman GI. Impaired hormonal responses to hypoglycemia in spontaneously diabetic and recurrently hypoglycemic rats. Reversibility and stimulus specificity of the deficits. The Journal of Clinical Investigation. 92: 2667-74. PMID 8254023 DOI: 10.1172/JCI116883  1
1993 Diamond MP, Jones T, Caprio S, Hallarman L, Diamond MC, Addabbo M, Tamborlane WV, Sherwin RS. Gender influences counterregulatory hormone responses to hypoglycemia. Metabolism: Clinical and Experimental. 42: 1568-72. PMID 8246771 DOI: 10.1016/0026-0495(93)90152-E  1
1993 Diamond MP, Grainger DA, Rossi G, Connolly-Diamond M, Sherwin RS. Counter-regulatory response to hypoglycemia in the follicular and luteal phases of the menstrual cycle. Fertility and Sterility. 60: 988-93. PMID 8243705  1
1993 Sherwin RS. Evaluation of hypoglycemic counterregulation using a modification of the Andres glucose clamp. Experimental Gerontology. 28: 371-80. PMID 8224035 DOI: 10.1016/0531-5565(93)90064-K  1
1993 Rashba EJ, Reich EP, Janeway CA, Sherwin RS. Type 1 diabetes mellitus: an imbalance between effector and regulatory T cells? Acta Diabetologica. 30: 61-9. PMID 8219259 DOI: 10.1016/B978-1-4377-1604-7.00236-0  1
1993 Rennert NJ, Boulware SD, Kerr D, Caprio S, Tamborlane WV, Sherwin RS. Metabolic effects of rhIGF-1 in normal human subjects. Advances in Experimental Medicine and Biology. 343: 311-8. PMID 8184741  1
1992 Caprio S, Boulware SD, Press M, Sherwin RS, Rubin K, Carpenter TO, Plewe G, Tamborlane WV. Effect of growth hormone treatment on hyperinsulinemia associated with Turner syndrome. The Journal of Pediatrics. 120: 238-43. PMID 1735819 DOI: 10.1016/S0022-3476(05)80434-2  1
1992 Boulware SD, Tamborlane WV, Matthews LS, Sherwin RS. Diverse effects of insulin-like growth factor I on glucose, lipid, and amino acid metabolism. The American Journal of Physiology. 262: E130-3. PMID 1733244  1
1992 Diamond MP, Reece EA, Caprio S, Jones TW, Amiel S, DeGennaro N, Laudano A, Addabbo M, Sherwin RS, Tamborlane WV. Impairment of counterregulatory hormone responses to hypoglycemia in pregnant women with insulin-dependent diabetes mellitus. American Journal of Obstetrics and Gynecology. 166: 70-7. PMID 1733221 DOI: 10.1016/0002-9378(92)91832-U  1
1992 Press M, Caprio S, Tamborlane WV, Bhushan R, Thorner M, Vale W, Rivier J, Sherwin RS. Pituitary response to growth hormone-releasing hormone in IDDM. Abnormal responses to insulin and hyperglycemia. Diabetes. 41: 17-21. PMID 1727733  1
1992 Jacob RJ, Sherwin RS, Greenawalt K, Shulman GI. Simultaneous insulinlike growth factor I and insulin resistance in obese Zucker rats. Diabetes. 41: 691-7. PMID 1587396  1
1992 Caprio S, Napoli R, Saccà L, Tamborlane WV, Sherwin RS. Impaired stimulation of gluconeogenesis during prolonged hypoglycemia in intensively treated insulin-dependent diabetic subjects. The Journal of Clinical Endocrinology and Metabolism. 75: 1076-80. PMID 1400874 DOI: 10.1210/jcem.75.4.1400874  1
1991 Caprio S, Gerety G, Tamborlane WV, Jones T, Diamond M, Jacob R, Sherwin RS. Opiate blockade enhances hypoglycemic counterregulation in normal and insulin-dependent diabetic subjects. The American Journal of Physiology. 260: E852-8. PMID 2058661  1
1991 Diamond MP, Hallarman L, Starick-Zych K, Jones TW, Connolly-Howard M, Tamborlane WV, Sherwin RS. Suppression of counterregulatory hormone response to hypoglycemia by insulin per se. The Journal of Clinical Endocrinology and Metabolism. 72: 1388-90. PMID 2026760 DOI: 10.1210/jcem-72-6-1388  1
1991 Caprio S, Boulware S, Diamond M, Sherwin RS, Carpenter TO, Rubin K, Amiel S, Press M, Tamborlane WV. Insulin resistance: an early metabolic defect of Turner's syndrome. The Journal of Clinical Endocrinology and Metabolism. 72: 832-6. PMID 2005209 DOI: 10.1210/jcem-72-4-832  1
1991 Jones TW, Boulware SD, Kraemer DT, Caprio S, Sherwin RS, Tamborlane WV. Independent effects of youth and poor diabetes control on responses to hypoglycemia in children. Diabetes. 40: 358-63. PMID 1999278  1
1991 Jacob RJ, Sherwin RS, Bowen L, Fryburg D, Fagin KD, Tamborlane WV, Shulman GI. Metabolic effects of IGF-I and insulin in spontaneously diabetic BB/w rats. The American Journal of Physiology. 260: E262-8. PMID 1996629  1
1991 Amiel SA, Caprio S, Sherwin RS, Plewe G, Haymond MW, Tamborlane WV. Insulin resistance of puberty: a defect restricted to peripheral glucose metabolism. The Journal of Clinical Endocrinology and Metabolism. 72: 277-82. PMID 1991798 DOI: 10.1210/jcem-72-2-277  1
1991 Jones TW, Caprio S, Diamond MP, Hallarman L, Boulware SD, Sherwin RS, Tamborlane WV. Does insulin species modify counterregulatory hormone response to hypoglycemia? Diabetes Care. 14: 728-31. PMID 1954809  1
1991 Reece EA, Coustan DR, Sherwin RS, Tuck S, Bates S, O'Connor T, Tamborlane WV. Does intensive glycemic control in diabetic pregnancies result in normalization of other metabolic fuels? American Journal of Obstetrics and Gynecology. 165: 126-30. PMID 1853889 DOI: 10.1016/0002-9378(91)90240-R  1
1990 Jones TW, McCarthy G, Tamborlane WV, Caprio S, Roessler E, Kraemer D, Starick-Zych K, Allison T, Boulware SD, Sherwin RS. Mild hypoglycemia and impairment of brain stem and cortical evoked potentials in healthy subjects. Diabetes. 39: 1550-5. PMID 2245879  1
1990 Caprio S, Amiel S, Tamborlane WV, Gelfand RA, Sherwin RS. Defective free-fatty acid and oxidative glucose metabolism in IDDM during hypoglycemia. Influence of glycemic control. Diabetes. 39: 134-41. PMID 2227120  1
1989 Cryer PE, Binder C, Bolli GB, Cherrington AD, Gale EA, Gerich JE, Sherwin RS. Hypoglycemia in IDDM. Diabetes. 38: 1193-9. PMID 2767340  1
1989 Reich EP, Scaringe D, Yagi J, Sherwin RS, Janeway CA. Prevention of diabetes in NOD mice by injection of autoreactive T-lymphocytes. Diabetes. 38: 1647-51. PMID 2684716  1
1989 Jacob R, Barrett E, Plewe G, Fagin KD, Sherwin RS. Acute effects of insulin-like growth factor I on glucose and amino acid metabolism in the awake fasted rat. Comparison with insulin. The Journal of Clinical Investigation. 83: 1717-23. PMID 2651479 DOI: 10.1172/JCI114072  1
1989 Caprio S, Gelfand RA, Tamborlane WV, Sherwin RS. Oxidative fuel metabolism during mild hypoglycemia: critical role of free fatty acids. The American Journal of Physiology. 256: E413-9. PMID 2646946  1
1989 Caprio S, Plewe G, Diamond MP, Simonson DC, Boulware SD, Sherwin RS, Tamborlane WV. Increased insulin secretion in puberty: a compensatory response to reductions in insulin sensitivity. The Journal of Pediatrics. 114: 963-7. PMID 2524556 DOI: 10.1016/S0022-3476(89)80438-X  1
1989 Reich EP, Sherwin RS, Kanagawa O, Janeway CA. An explanation for the protective effect of the MHC class II I-E molecule in murine diabetes. Nature. 341: 326-8. PMID 2507922 DOI: 10.1038/341326a0  1
1988 Amiel SA, Sherwin RS, Simonson DC, Tamborlane WV. Effect of intensive insulin therapy on glycemic thresholds for counterregulatory hormone release. Diabetes. 37: 901-7. PMID 3290007  1
1988 Merkel PA, Simonson DC, Amiel SA, Plewe G, Sherwin RS, Pearson HA, Tamborlane WV. Insulin resistance and hyperinsulinemia in patients with thalassemia major treated by hypertransfusion. The New England Journal of Medicine. 318: 809-14. PMID 3281000 DOI: 10.1056/NEJM198803313181303  1
1988 Caprio S, Saccà L, Tamborlane WV, Sherwin RS. Relationship between changes in glucose production and gluconeogenesis during mild hypoglycemia in humans. Metabolism: Clinical and Experimental. 37: 707-10. PMID 3043143 DOI: 10.1016/0026-0495(88)90001-7  1
1982 Dharmsathaphorn K, Gorelick FS, Sherwin RS, Cataland S, Dobbins JW. Somatostatin decreases diarrhea in patients with the short-bowel syndrome. Journal of Clinical Gastroenterology. 4: 521-4. PMID 6131090  1
1980 Dharmsathaphorn K, Sherwin RS, Dobbins JW. Somatostatin inhibits fluid secretion in the rat jejunum. Gastroenterology. 78: 1554-8. PMID 6102948  1
1975 Insel PA, Liljenquist JE, Tobin JD, Sherwin RS, Watkins P, Andres R, Berman M. Insulin control of glucose metabolism in man: a new kinetic analysis. The Journal of Clinical Investigation. 55: 1057-66. PMID 15959962 DOI: 10.1172/JCI108006  1
1974 Sherwin RS, Kramer KJ, Tobin JD, Insel PA, Liljenquist JE, Berman M, Andres R. A model of the kinetics of insulin in man. The Journal of Clinical Investigation. 53: 1481-92. PMID 4856884 DOI: 10.1172/JCI107697  1
1974 Insel PA, Kramer KJ, Sherwin RS, Liljenquist JE, Tobin JD, Andres R, Berman M. Modeling the insulin-glucose system in man. Federation Proceedings. 33: 1865-8. PMID 4834190  1
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